CN115670952A - Oil-control anti-acne composition, skin care product and preparation method - Google Patents
Oil-control anti-acne composition, skin care product and preparation method Download PDFInfo
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- CN115670952A CN115670952A CN202211411133.9A CN202211411133A CN115670952A CN 115670952 A CN115670952 A CN 115670952A CN 202211411133 A CN202211411133 A CN 202211411133A CN 115670952 A CN115670952 A CN 115670952A
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Abstract
The invention discloses a composition for controlling oil and resisting acne, a skin care product and a preparation method thereof, wherein the composition comprises the following components: 1-8 parts of bioflavonoid, 0.1-30 parts of PCA zinc, 2-15 parts of olive leaf extract, 0.1-10 parts of ascorbic acid, 1-5 parts of bisabolol, 0.1-10 parts of ginger extract and 1-10 parts of jojoba seed oil; the skin care product comprises 0.53 to 16 percent of the composition, 1 to 14 percent of emulsifier, 1 to 10.5 percent of humectant, 0.2 to 1 percent of antioxidant and the balance of water; the method comprises the following steps: heating, stirring and mixing an antioxidant, water, a partial humectant and a partial emulsifier until the mixture is completely transparent; adding the rest part of emulsifier, homogenizing, stirring and cooling to 42-50 ℃ to obtain a mixture B; adding the composition and the rest of the humectant into the mixture B, and stirring thoroughly to obtain skin care product; the invention has good moisture retention while resisting acne and controlling oil.
Description
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to an oil-control and anti-acne composition, a skin care product and a preparation method of the skin care product.
Background
Oily skin is most commonly found in adolescence and some people with high androgen levels or androgen-sensitive receptors in the body, and nearly 40% of the people find hypersecretion of their skin oil. Therefore, the product with full of enamel for controlling oil and removing acne appears.
Most products in the market mostly use salicylic acid, tartaric acid and other components to dredge pores or use powerful disinfection and bacteriostasis components to kill skin flora so as to achieve the purposes of removing acnes and controlling oil. But the normal protective barrier stratum corneum, oil-water balance and microorganism balance of the skin are easily damaged, so that the phenomenon of repeated acne is caused in a short term and the phenomenon of repeated acne is caused in a long term. The existing acne removing technology is, for example, an anti-inflammatory acne removing skin care composition with the patent number of CN202011629478.2, and a preparation method and a using method thereof, wherein the anti-inflammatory acne removing skin care composition comprises the following components in percentage by total mass of 100 percent: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; in the anti-inflammatory acne-removing skin care composition, the aqueous phase comprises: salicylic acid 0.1-2%, fruit acid 0-6%, skin conditioner 0-10%, preservative 0.1-1%, and water in balance; in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 0.1 to 10 percent of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0 to 2.9 percent of other grease. The anti-inflammatory acne-removing skin care composition has the effects of resisting inflammation and removing acnes through the synergistic effect of the components in the oil phase and the water phase, is mild in skin effect, small in irritation, capable of softening and moisturizing the skin, capable of protecting skin barriers and avoiding the formation of oily sensitive skin. But the acid substances such as salicylic acid, composite fruit acid or nicotinamide and the like are adopted: the purposes of controlling oil and removing acnes are achieved by peeling off the cuticle, dredging pores, dissolving grease and promoting metabolism; it is too thin for the stratum corneum to be easily exposed to external stimuli and infections. In the prior art, the materials such as fomes fomentarius and mycelium extracts are as follows: more, the soothing effect is achieved, and the oil control and acne removing effects are not obvious.
In addition, most emulsion products on the market need to be heated to help melt grease and improve the emulsification effect, so that the whole production preparation period is long, and the main problems are that the heating time is long, the cooling speed is slow, and the active ingredients lose effectiveness due to the high-temperature stirring time and the homogenization for a long time.
Disclosure of Invention
The invention aims to solve the technical problems that the components adopted in the prior art are easy to damage the normal protective barrier stratum corneum of the skin, oil-water balance and microbial balance, and the acne is easy to explode repeatedly, and the active ingredients are ineffective due to long production and preparation period, long heating time, low cooling speed, high-temperature stirring time and long homogenization.
In order to solve the technical problems, the invention adopts the following technical scheme:
on one hand, the invention provides an oil-controlling and anti-acne composition, which comprises the following raw materials in parts by mass: 1 to 8 parts of bioflavonoid, 0.1 to 30 parts of PCA zinc, 2 to 15 parts of olive leaf extract, 0.1 to 10 parts of ascorbic acid, 1 to 5 parts of bisabolol, 0.1 to 10 parts of ginger extract and 1 to 10 parts of jojoba seed oil.
The bioflavonoid maintains the ecological balance angle between beneficial bacteria and harmful bacteria on the skin surface layer, so that the bioflavonoid can be propagated on the skin surface according to a normal physiological state, fatty acid can be stably secreted, the pH value of the epidermis can be stabilized, the PCA zinc can regulate the sebum secretion amount, reduce the activity of lipidase, and deeply and timely control oil; through reasonable proportioning of the compositions, the composition disclosed by the invention can achieve the effects of controlling oil secretion and controlling Vickers through advantageous combination. After the skin care product is smeared on the skin, the microbial flora on the surface of the skin can be balanced, the harmful bacteria flora is prevented from being excessively bred, and the survival of the beneficial bacteria flora is not influenced; the acne removing cream has the effects of removing acnes, relieving oil control, improving the resistance of skin to external stimulation, reducing the probability of microecological imbalance of skin, and effectively improving the capacity of resisting acnes relapse and preventing acnes for a long time.
The skin micro-ecology is optimized by inhibiting propionibacterium acnes through the bioflavonoids and the olive leaf extract, the balance group of the propionibacterium acnes is rebuilt, the inflammatory reaction is inhibited, the 5 alpha-reductase is blocked, the sebaceous gland cells are restored to the normal state, the anti-acne effect is achieved from the skin micro-ecology layer, and meanwhile, the effects of brightening the skin, fading the skin and preventing the acne marks from becoming dark are achieved.
The further technical scheme of the invention is as follows: the composition comprises the following raw materials in parts by mass: 3-6 parts of bioflavonoid, 10-20 parts of PCA zinc, 2-10 parts of olive leaf extract, 5-10 parts of ascorbic acid, 4-5 parts of bisabolol, 3-8 parts of ginger extract and 3-8 parts of jojoba seed oil.
The further technical scheme of the invention is as follows: the bioflavonoid is extracted from folium Broussonetiae.
The variety of biological 'flavonoids' is wide, and the flavonoid from the leaves of the broussonetia papyrifera is used in the invention.
On the other hand, the invention also provides an oil-controlling and anti-acne skin care product, which comprises 0.53-16% of the composition, 1-14% of an emulsifier, 1-10.5% of a humectant, 5-8% of an antioxidant and the balance of water by mass.
The invention further adopts the technical scheme that: the skin care product comprises the following components in percentage by mass based on 100% of the weight of the skin care product: 0.1 to 2.0 weight percent of hydrogenated polydecene, 0.2to 2.0 weight percent of tridecyl alcohol polyether-10, 0.1 to 5.0 weight percent of glycerol stearate citrate, 0.1 to 3.0 weight percent of sodium polyacryl dimethyl taurate and 0.5 to 2.0 weight percent of hydrogenated olive oil unsaponifiable matter.
The further technical scheme of the invention is as follows: the moisturizer comprises the following components in percentage by mass based on 100% of the weight of the skin care product: 0.1 to 3.0 weight percent of hydrogenated olive oil acid ethylhexyl ester, 0.1 to 3.0 weight percent of isononyl isononanoate, 0.2 to 1.0 weight percent of 1,2-hexanediol, 0.5 to 3.0 weight percent of glycerin and 2 to 3 weight percent of 1,3-propylene glycol.
The further technical scheme of the invention is as follows: the antioxidant comprises the following components in percentage by mass based on 100% of the weight of the skin care product: 1,3 butanediol 5wt% to 8wt%.
The invention mainly uses the biological flavonoid to maintain the ecological balance angle between beneficial bacteria and harmful bacteria on the surface layer of the skin, so that the skin surface can be propagated according to the normal physiological state, the skin surface can stably secrete fatty acid and stabilize the pH value of the skin, in addition, the glycerin can also carry out deep moisture preservation after supplementing the water lost by oily skin, so that the oil-water of the skin can be balanced, the survival condition more suitable for maintaining the microbial population on the skin is provided, and the natural state of the skin is restored; the zinc element of the PCA zinc can regulate sebum secretion, reduce the activity of lipidation ferment and deeply and timely control oil; the hydrogenated ethylhexyl olivate and isononyl isononanoate in the humectant provide a light water-in-oil emulsifying system, which is easier to apply and absorb and is the most suitable emulsifier for the oil skin.
On the other hand, the invention also provides a preparation method of the oil-control anti-acne skin care product, which is characterized by comprising the following steps:
the method comprises the following steps: weighing the humectant, the emulsifier, the composition and the antioxidant according to the corresponding mass percentage;
step two: mixing jojoba seed oil, antioxidant, water, part of humectant and part of emulsifier in the composition, and stirring to obtain mixture A;
step three: adding the rest of emulsifier, the rest of water, the rest of humectant and the rest of composition into the mixture A, homogenizing, and stirring to obtain the skin care product;
the partial emulsifier is calculated by taking the weight of the skin care product as 100 percent: 0.1 to 5.0 weight percent of glycerol stearate citrate and 0.5 to 2.0 weight percent of hydrogenated olive oil unsaponifiable matter; the remaining part of the emulsifiers were: 0.1 to 2.0 weight percent of hydrogenated polydecene, 100.2 to 2.0 weight percent of tridecyl alcohol polyether and 0.1 to 3.0 weight percent of sodium polyacryl dimethyl taurate;
the skin care product comprises the following components in part by weight of 100 percent: hydrogenated olive oil acid ethylhexyl ester 0.1wt% -3.0 wt%, isononyl isononanoate 0.1wt% -3.0 wt% and 1,2-hexanediol 0.2wt% -1.0 wt%; the remaining portion of the humectants was: 0.5wt% -3.0 wt% of glycerin and 1,3-propylene glycol 2wt% -3 wt%.
The further technical scheme of the invention is as follows: and in the step two, mixing and stirring are carried out for 15-60 min, and in the step three, homogenizing and stirring are carried out for 1-10 min.
In the preparation method of the skin care product, the composition, the humectant and the emulsifier are added in two groups in different steps, so that the solubility of active substances and grease is enhanced, high-temperature dissolution and excessive stirring are not needed, the preparation time can be effectively shortened, the active ingredients are prevented from being damaged, and the failure of the active ingredients caused by heating treatment and cooling treatment is avoided in the preparation of the skin care product.
Ingredients in the composition of the invention:
isononyl isononanoate: the emollient is commonly called silk oil, is light grease, is not sticky to skin and has good spreadability; and overcomes the problem of too sticky natural oil and solves the problem of poor air permeability of mineral oil and silicone oil, and is an ideal oil special for oil skins.
Hydrogenated olive oil unsaponifiables: the emollient can be used as a plant source substitute of silicone oil, is an oil skin-friendly skin care oil, and has stable odor, color and key indexes at high temperature.
Glyceryl stearate citrate: the emollient has excellent skin feeling, light weight and low irritation to mucous membranes such as eyes, and is a skin-friendly additive.
1,3 butanediol: the product is often used as an efficient solvent, can fully dissolve active ingredients with poor water solubility and water-insoluble grease, can also be used as a humectant and an antioxidant, and has an inhibiting effect on common germs.
1,2 hexanediol: the humectant has water locking and antibacterial effects.
1,3-propanediol: is commonly used as a solvent, can fully dissolve active ingredients with poor water solubility and water-insoluble grease, and also can be used as a penetrating agent and a humectant.
Olive leaf extract: has effect in inhibiting Propionibacterium acnes activity, and can be used for preventing and treating pox; meanwhile, the acne cream can also phagocytize melanin, brighten skin and fade black, and prevent acne marks from becoming dark.
Bioflavonoids: an active agent for controlling oil and maintaining microecology, optimizes skin microecology by inhibiting Propionibacterium acnes, reconstructs the balance group of Propionibacterium acnes, inhibits inflammatory reaction, blocks 5 alpha-reductase, and restores sebaceous gland cells to a precursor state.
Zinc PCA: the oil control active component, wherein the zinc element can regulate sebum secretion, reduce the activity of the lipidization ferment and deeply and timely control oil.
And other skin conditioners and other auxiliary materials are added, so that the use of the preparation product can be further ensured to fundamentally balance the micro-ecology of the skin surface and balance the oil-water ratio of the skin, and the effect of preventing the acne from recurring easily is achieved.
The invention has the beneficial effects that: the bioflavonoid and the olive leaf extract are adopted to optimize skin micro-ecology by inhibiting propionibacterium acnes, reconstruct a balanced group of propionibacterium acnes, inhibit inflammatory reaction, block 5 alpha-reductase and restore sebaceous gland cells to a normal state, achieve the anti-acne effect from the skin micro-ecology layer, and have the effects of brightening skin, fading black and preventing acne marks from becoming dark; the zinc PCA is matched to regulate sebum secretion, reduce the activity of lipidation ferment and control oil from a cell level to a deep layer in time; therefore, the micro-ecological layer of the epidermis is adjusted, the balance of micro-ecology is maintained, compared with the prior art, the micro-ecological layer does not damage the protective barrier stratum corneum, is also suitable for sensitive skin, can not explode acne repeatedly, and has good anti-acne effect; the anti-acne oil-control fabric has good moisture retention property;
according to the invention, the skin-friendly emulsifying wetting agent such as isononyl isononanoate, hydrogenated olive oil ethylhexyl oleate, hydrogenated olive oil unsaponifiable matter and the like is used, so that the lipid loss between skin cuticle plates is further reduced, and the skin feel is more refreshing and easier to apply compared with common oil control products on the market;
in the preparation method of the skin care product, the composition, the humectant and the emulsifier are added in two groups in different steps, so that the solubility of active substances and grease is enhanced, high-temperature dissolution and excessive stirring are not needed, the preparation time can be effectively shortened, and the active ingredients are prevented from being damaged, so that the failure of the active ingredients caused by heating treatment and cooling treatment is avoided in the preparation of the skin care product;
the preparation method is simple and easy to operate, is beneficial to production and industrial popularization, and has high economic value.
Drawings
FIG. 1 is a graph showing the relationship between bioflavonoids, skin oil growth rate and stratum corneum skin growth rate.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention.
It should be noted that the structures, ratios, sizes, and the like shown in the drawings attached to the present specification are only used for matching the disclosure of the present specification, so as to be understood and read by those skilled in the art, and are not used to limit the conditions of the present invention, so that the present invention has no technical essence, and any structural modification, ratio relationship change, or size adjustment should still fall within the scope of the present invention without affecting the efficacy and the achievable purpose of the present invention. In addition, the terms "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for clarity of description, and are not intended to limit the scope of the present invention, and the relative relationship between the terms and the terms is not to be construed as a scope of the present invention.
In the following examples and comparative examples bioflavonoids were extracted from the leaves of Broussonetia papyrifera, and zinc PCA was purchased from Oalli corporation, shanghai; hydrogenated olive oil ethylhexyl oleate, hydrogenated olive oil unsaponifiables are available from claine.
Example 1
The composition for controlling oil and resisting acne comprises the following components:
glyceryl stearate citrate 2.5g, isononyl isononanoate 1.5g, hydrogenated olive oil ethylhexyl oleate 1.0g, hydrogenated olive oil unsaponifiable matter 2.0g, glycerol 0.5g, 1,3-propanediol 3.0g, 1,2-hexanediol 0.6g, hydrogenated polydecene 0.6g, trideceth-10.4g, sodium polyacryloyldimethyltaurate 1.0g, bioflavonoid 3.0g, bisabolol 0.4g, ginger extract 0.3g, olive leaf extract 0.2g, 1,3-butanediol 8.0g, zinc PCA 0.1g, ascorbic acid 0.1g, jojoba oil 0.3g and water added to 100g.
The specific amounts of the above components are shown in Table 1 (unit is g)
A method of making a skin care product comprising the composition for controlling oil and combating acne of example 1, comprising the steps of:
step S-1, selecting jojoba seed oil, isononyl isononanoate, hydrogenated olive oil unsaponifiable matter, glyceryl stearate citrate, hydrogenated olive oil ethylhexyl oleate, tridecyl polyether-10, hydrogenated polydecene and 1,3-butanediol according to corresponding mass fractions, mixing, uniformly stirring, then adding partial water, diluting and stirring for 30min to obtain a mixed solution A;
and S-2, adding sodium polyacryl dimethyl taurate, residual water, glycerol, an olive leaf extract, bisabolol, bioflavonoids, a ginger root extract, ascorbic acid, PCA zinc and 1,3-propylene glycol into the mixed solution A, starting homogenizing for 3min, and finally fully and uniformly stirring to complete the preparation.
Example 2
A skin care product for controlling oil and resisting acne is different from the skin care product in example 1 only in that no bioflavonoid is added, and the dosage of the other components is kept consistent. See table 1 (units in g) for details.
Example 3
A skin care product for controlling oil and resisting acne is different from the skin care product in example 1 only in that the dosage of the bioflavonoid is 0.5g, and the dosages of the other components are kept consistent. See table 1 (units in g) for details.
Example 4
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that the dosage of the bioflavonoid is 1.0g, and the dosages of the other components are basically the same. See table 1 (units in g) for details.
Example 5
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that the dosage of the bioflavonoid is 2.0g, and the dosages of the other components are basically the same. See table 1 (units in g) for details.
Example 6
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that the dosage of the bioflavonoid is 4.0g, and the dosages of the other components are basically the same. See table 1 (units in g) for details.
Example 7
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that the dosage of the bioflavonoid is 5.0g, and the dosages of the other components are basically the same. See table 1 (units in g) for details.
Comparative example 1
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that olive leaf extract is not added, water with the same weight is used instead, and the using amount of the other components is basically the same.
Comparative example 2
An oil and acne control skin care product is different from the skin care product in example 1 only in that no zinc PCA is added, water with the same weight is used, and the amount of the other components is basically the same.
Comparative example 3
An oil-controlling and anti-acne skin care product is different from the skin care product in example 1 only in that zinc PCA and olive leaf extract are not added, water with the same weight is used instead, and the using amount of the other components is basically the same.
The formulation tables in examples 1-7 above, and comparative examples 1-3 are shown in Table 1:
table 1: prescription table for each case
Experiment of
Skin oil level test
1. Principle of experiment
The measurement of the skin oil content is mostly applied to the research of the efficacy of cosmetics and is one of the important indexes for evaluating the oil control efficacy, the anti-acne (anti-acne) effect and the like of the cosmetics. The oil spot photometer based on the principle works, a special extinction adhesive tape with the thickness of 0.1mm is pasted on the skin, after oil on the skin of a human body is absorbed, the adhesive tape becomes a semitransparent adhesive tape, and the light transmission quantity is correspondingly changed, so that the transparency is proportional to the oil quantity, the more the absorbed oil is, the larger the light transmission quantity is, and the oil content of the skin is measured by measuring the light transmission quantity of the adhesive tape.
2. Experimental protocol
100 volunteers 18-45 years old are selected as trial subjects, 100 volunteers are randomly divided into 10 groups (10 in each group, consisting of 4 males and 6 females) to test each embodiment and the proportion, and the skin of the test subject is healthy and meets the selection standard (the skin is determined to be oil skin, and the skin is more than 120 mu g/cm < 2 >). Instructions for use of the product are provided to the subject, after which the product is dispensed, and the subject uses the test sample as required, and the instrument tests are performed the same day as the subject and on day 28 after using the oil and pox control emulsion skin care product.
3. Test method
The volunteers use the oil-controlling anti-acne emulsion skin care product on the face in the morning and at the evening for 28 days, the test day arrives at a laboratory, the face is washed by clear water before the test, the test subjects take a rest for 30min at a constant temperature and humidity of 22 ℃ plus or minus 2 ℃ and 50 percent plus or minus 10 percent, then the instrument test is carried out, and a sebum probe and a skin moisture probe of a Sebumeter SM815 (German CK) are used for respectively and continuously testing for 3 times to obtain an average value.
The smaller the value of the sebum (unit: mu g/cm 2) parameter, the lower the skin oil content, and vice versa;
the smaller the value of the moisture (unit:%) parameter, the lower the skin moisture content and vice versa;
calculating the oil clearance rate and the skin moisture growth rate according to the test value of the day 28 on the test day;
the calculation method comprises the following steps:
fat removal rate = (D28 fat D0 fat)/D0 fat × 100%;
skin moisture growth rate = (D28 moisture-D moisture)/D0 moisture × 100%;
the test results are shown in Table 2.
Table 2: experimental data sheet
The following conclusions can be drawn by performing single factor analysis on the above data:
1. of the 100 volunteers, 92 showed significant oil control and 84 showed significant moisturizing in the test data.
2. The influence of the addition amount of bioflavonoids, the oil control effect and the water retention effect is detailed in figure 1: the conclusion is as follows:
(1) in the addition range of 0-5%, the higher the addition amount of the bioflavonoids, the better the oil control effect;
(2) when the addition amount of the bioflavonoids is more than 3 percent, the enhancement effect of the oil control capacity is not obvious;
(3) in the addition range of 0-3%, the higher the addition amount of the bioflavonoids, the higher the stratum corneum moisture growth rate;
(4) when the addition amount of the bioflavonoids is more than 3 percent, the moisture increase rate of the stratum corneum begins to decrease;
(5) considering the comprehensive cost and effect, the addition amount of 3 percent is preferably selected, so that the oil control effect and the moistening and moisturizing effect are both sufficient.
3. Oil control capability and water replenishing capability comparison table for different oil control combinations
| Oil control combination | Clearance rate of skin oil% | The moisture increase rate of skin% |
| 3% bioflavonoid + zinc PCA + olive leaf extract | 34.17 | 47.71 |
| 3% bioflavonoid + zinc PCA | 28.44 | 33.82 |
| 3% bioflavonoid + olive leaf extract | 20.72 | 32.3 |
| 3% bioflavonoid | 17.73 | 32.7 |
Therefore, the oil control and moisturizing effect of the combination of the bioflavonoids, the olive leaf extract and the PCA zinc is obviously superior to that of the combination of the bioflavonoids, the olive leaf extract and the PCA zinc and the use of the bioflavonoids alone compared with the combination of the bioflavonoids, the olive leaf extract and the PCA zinc and the use of the bioflavonoids alone; the corresponding preparation method of the skin care product is carried out at normal temperature, so that the heating step is reduced, the loss of active ingredients is avoided, and the oil control and moisture retention effects are obviously higher than those in the prior art.
The present invention is not limited to the above-described preferred embodiments, but includes all modifications, equivalents, and improvements within the spirit and scope of the present invention.
Claims (9)
1. A composition for controlling oil and resisting acne is characterized in that: the composition comprises the following raw materials in parts by mass: 1 to 8 parts of bioflavonoid, 0.1 to 30 parts of PCA zinc, 2 to 15 parts of olive leaf extract, 0.1 to 10 parts of ascorbic acid, 1 to 5 parts of bisabolol, 0.1 to 10 parts of ginger extract and 1 to 10 parts of jojoba seed oil.
2. The oil-control and anti-acne composition according to claim 1, characterized by comprising the following raw materials in parts by mass: 3-6 parts of bioflavonoid, 10-20 parts of PCA zinc, 2-10 parts of olive leaf extract, 5-10 parts of ascorbic acid, 4-5 parts of bisabolol, 3-8 parts of ginger extract and 3-8 parts of jojoba seed oil.
3. The composition of claim 1, wherein the bioflavonoids are derived from the extraction of the leaves of Broussonetia papyrifera.
4. A skin care product for controlling oil and resisting acne, which is characterized by comprising 0.53-16% of the composition as defined in any one of claims 1-3 by mass, 1-14% of an emulsifier, 1-10.5% of a humectant, 5-8% of an antioxidant and the balance of water.
5. The oil-control anti-acne skin care product according to claim 4, characterized in that the emulsifier comprises the following components in percentage by mass based on 100% of the weight of the skin care product: 0.1 to 2.0 weight percent of hydrogenated polydecene, 0.2to 2.0 weight percent of tridecyl alcohol polyether-10, 0.1 to 5.0 weight percent of glycerol stearate citrate, 0.1 to 3.0 weight percent of sodium polyacryl dimethyl taurate and 0.5 to 2.0 weight percent of hydrogenated olive oil unsaponifiable matter.
6. The oil-control and anti-acne skin care product according to claim 4, wherein the moisturizer comprises the following components in percentage by mass based on 100 percent of the weight of the skin care product: 0.1 to 3.0 weight percent of hydrogenated olive oil ethyl hexyl oleate, 0.1 to 3.0 weight percent of isononyl isononanoate, 0.2 to 1.0 weight percent of 1,2-hexanediol, 0.5 to 3.0 weight percent of glycerin and 2 to 3 weight percent of 1,3-propylene glycol.
7. The oil-control anti-acne skin care product according to claim 4, wherein the antioxidant comprises the following components in percentage by mass based on 100% of the weight of the skin care product: 1,3 butanediol 5wt% to 8wt%.
8. A method for preparing the oil-controlling and anti-acne skin care product of any one of claims 4 to 7, wherein the method for preparing the oil-controlling and anti-acne skin care product comprises the following steps:
the method comprises the following steps: weighing the humectant, the emulsifier, the composition and the antioxidant according to corresponding mass percentages;
step two: mixing jojoba seed oil, antioxidant, water, part of humectant and part of emulsifier in the composition, and stirring to obtain mixture A;
step three: adding the rest of emulsifier, the rest of water, the rest of humectant and the rest of composition into the mixture A, homogenizing, and stirring to obtain the skin care product;
the partial emulsifier is calculated by taking the weight of the skin care product as 100 percent: 0.1 to 5.0 weight percent of glycerol stearate citrate and 0.5 to 2.0 weight percent of hydrogenated olive oil unsaponifiable matter; the remaining part of the emulsifiers were: 0.1 to 2.0 weight percent of hydrogenated polydecene, 100.2 to 2.0 weight percent of tridecyl alcohol polyether and 0.1 to 3.0 weight percent of sodium polyacryl dimethyl taurate;
the skin care product comprises the following components in part by weight of 100 percent: hydrogenated olive oil acid ethylhexyl ester 0.1wt% -3.0 wt%, isononyl isononanoate 0.1wt% -3.0 wt% and 1,2-hexanediol 0.2wt% -1.0 wt%; the remaining portion of the humectants was: 0.5 to 3.0 weight percent of glycerin and 1,3-propanediol 2 to 3 weight percent.
9. The method for preparing the oil-controlling and anti-acne skin care product according to claim 8, characterized in that the mixing and stirring step in the second step is carried out for 15-60 min, and the homogenizing and stirring step in the third step is carried out for 1-10 min.
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| WO2004096169A1 (en) * | 2003-04-29 | 2004-11-11 | Provincia Italiana Della Congregazione Dei Figli Dell'immacolata Concezione - Istituto Dermopatico Dell'immacolata | Dermatological formulation |
| CN113425650A (en) * | 2021-08-16 | 2021-09-24 | 深圳八零赞电子商务有限公司 | Oil control composition containing plant active ingredients |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2004096169A1 (en) * | 2003-04-29 | 2004-11-11 | Provincia Italiana Della Congregazione Dei Figli Dell'immacolata Concezione - Istituto Dermopatico Dell'immacolata | Dermatological formulation |
| CN113425650A (en) * | 2021-08-16 | 2021-09-24 | 深圳八零赞电子商务有限公司 | Oil control composition containing plant active ingredients |
Non-Patent Citations (2)
| Title |
|---|
| 李小迪: "协同增效抗痘系列化妆品配方开发", 香料香精化妆品, no. 03, pages 40 - 45 * |
| 美际生物科技（上海）有限公司: "百植萃舒缓修红亮颜面膜", pages 1 - 3, Retrieved from the Internet <URL:https://hzpba.nmpa.gov.cn/gccx/chakan.html?prodId=1012390700106383360&gb=G> * |
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