CN115607821A - Linear plastic deformation radiation device - Google Patents

Abstract

The invention provides a linear plastic deformation radiation device, which comprises a memory alloy tube and a silver wire arranged in the memory alloy tube, wherein radioactive nuclide is plated on the silver wire. The linear plastic deformation radiation device has good conformability with the cavity, and overcomes the defects of complex operation, uneven dose distribution and the like of the matching use of the existing granular radiation source and the bracket.

Description

Linear plastic deformation radiation device

Technical Field

The invention relates to a linear plastic deformation radiation device.

Background

The late stage of malignant tumor of portal vein, biliary tract, esophagus, airway, urethra and other cavity system is mainly manifested as obstructive symptom, the curative effect of traditional radiotherapy and chemotherapy is not good enough, and at present, a stent is mostly adopted to solve the obstructive symptom. However, although the traditional stent implantation can quickly relieve obstruction symptoms, the traditional stent implantation has no treatment effect on tumors, and the restenosis rate is high along with the continuous growth of the tumors after the operation. Because the radioactive seeds are implanted in a close range for irradiation, the growth of tumors can be effectively controlled, in recent years, the radiation scheme of the radioactive seeds and the bracket implanted in the particle-bracket is applied to the treatment of malignant tumors of a cavity system, the effect of treating the tumors is achieved while obstruction symptoms are relieved, and the incidence rate of cavity restenosis is reduced.

At present, the internal irradiation mode of granular radioactive particles and bracket combined implantation is mainly adopted for clinically solving obstruction of a cavity system, and the internal irradiation mode mainly has three forms: particle strip combination support, support loading particle, particle support (carrying) ¹²⁵ The I particle source) + inner support bracket, three inner irradiation schemes are complex to operate, radioactive particles need to be filled by hands, a large-diameter sheath is usually needed when the bracket enters a cavity after assembly, the wound is large, the process at the current stage is rough, the adaptability and the controllability of the cavity are poor, the granular radioactive particles are large in displacement after the bracket is released, the space distribution and the dosage of the radioactive particles are uneven, and the serious influence is causedHas good therapeutic effect and limited clinical application.

Disclosure of Invention

The invention aims to provide a linear plastic deformation radiation device which has a memory and reshaping function, has good shape adaptability of a cavity and reasonable dose distribution, realizes good matching of the radiation device and a bracket and simplifies the operation process of an operation.

In order to realize the purpose, the technical scheme is as follows: the linear plastic deformation radiation device comprises a memory alloy tube and a silver wire arranged in the memory alloy tube, wherein the silver wire is plated with radionuclide.

Preferably, the material of the memory alloy tube is nickel titanium memory alloy.

Preferably, the memory alloy tube is a linear or spiral memory alloy tube.

Preferably, the radionuclide is distributed intermittently or continuously on the silver wire.

Preferably, the silver wire is provided with a shielding material, so that the radioactive nuclide is discontinuously distributed on the silver wire. Preferably, the radionuclide is distributed on the silver wire in a uniform discontinuous distribution.

Preferably, the shielding material is polyimide.

Preferably, the radionuclide is selected from iodine-125, palladium-103, holmium-166, cesium-131, and gold-198.

Preferably, both ends of the memory alloy tube are welded and sealed.

Has the advantages that:

1. improve the structural performance of the existing granular radioactive source: the invention provides a novel linear plastic deformation radiation device which can be deformed, is matched with a bracket after being deformed and well conforms to a cavity channel by directly filling radioactive nuclide in a nickel-titanium memory alloy tube by means of a physical material with memorability and conformability, and overcomes the defects of complex operation, uneven dose distribution and the like of the traditional internal irradiation bracket.

2. Optimizing the dose distribution of existing internal irradiation stents: due to the unique design of the linear plastic deformation radiation device, a doctor can deform the linear plastic deformation radiation device according to parameters such as the diameter of a cavity, a lesion part and the length, the three-dimensional dose distribution of a radiation source is accurately matched with the dose of a tumor target area, the accurate control of individual dose is realized, and the accurate internal irradiation of malignant tumors of the cavity is really realized.

Drawings

FIG. 1 is a schematic structural diagram of a linear plastic deformation radiation device according to the present invention.

FIG. 2 is a longitudinal cross-sectional view of the linear plastically deformable radiation device of the present invention.

FIG. 3 is a cross-sectional view of a linear plastically deformable radiation device in accordance with the invention.

Fig. 4 is a schematic view of the structure of the silver wire with radionuclide and a shielding material according to the present invention.

Fig. 5 is a longitudinal cross-sectional view of a silver wire with a radionuclide and a shielding material of the present invention.

FIG. 6 is a spiral deformation diagram of the linear plastic deformation radiation device of the present invention.

In the figure: 1. memory alloy pipe 2, hollow structure of the alloy pipe 3, silver wire 4, radioactive nuclide 5, shielding material 6 and welding seal point.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.

As shown in fig. 1-3, a linear plastic deformation radiation device comprises a memory alloy tube 1 and a silver wire 3 arranged in the memory alloy tube, wherein the silver wire 3 is positioned in a hollow structure 2 of the nickel-titanium alloy tube, and the silver wire 3 is plated with radionuclide 4. The nitinol tube 1 is preferably a shape memory alloy tube.

Furthermore, the material of the memory alloy tube 1 is nickel titanium memory alloy, and the memory alloy tube can be plastically deformed. Further, the radionuclide 4 is distributed on the silver wire 3 intermittently or continuously. As shown in fig. 4 and 5, the present invention provides a shielding material 5 on the silver wire 3, so that the radionuclide 4 is discontinuously distributed on the silver wire 3. Preferably, the radionuclide 4 is distributed on the silver wire 3 in a uniform discontinuous distribution. Preferably, the material of the shielding material 5 is Polyimide (abbreviated as PI). According to the invention, the shielding material 5 is discontinuously plated on the silver wire 3, then the radioactive nuclide 4 is plated on the silver wire 3, and the radioactive nuclide 4 on the silver wire 3 is positioned between the shielding materials 5 because the radioactive nuclide 4 cannot be plated on the shielding material 5. Further, the radionuclide 4 is selected from iodine-125, palladium-103, holmium-166, cesium-131 and gold-198.

Further, the two ends of the memory alloy tube 1 are sealed and welded. The silver wire 3 plated with the radioactive nuclide 4 is filled into the memory alloy tube 1, the two ends are sealed by welding, the end part of the memory alloy tube 1 is a welding point 6 to prevent the nuclide from leaking, and the linear plastic deformation radiation device is manufactured.

As shown in fig. 1-3, the memory alloy tube may be a linear memory alloy tube, and as shown in fig. 6, the memory alloy tube may also be deformed into a helical memory alloy tube.

The invention directly loads radioactive nuclide in the nickel-titanium alloy tube to prepare the linear radioactive source with discontinuously distributed nuclides, and does not use the existing commercial granular radioactive sources to arrange the radioactive sources into a linear or strip shape, thereby really realizing the controllable distribution of the radioactive sources.

When the linear plastic deformation radiation device is used in combination with a stent, the linear plastic deformation radiation device is bound, wound or woven into the stent and implanted into a diseased part of a human body cavity to generate the function of short-distance irradiation.

When used alone, the linear plastic deformation radiation device is pre-deformed into a spiral shape and implanted into a lesion part of a cavity of a human body, and simultaneously has the functions of supporting the cavity and irradiating at a short distance. The irradiation dose of the linear plastic deformation irradiation device can be adjusted by changing the distribution interval and activity of the radionuclides plated on the silver wire.

The length and the shape of the linear plastic deformation radiation device are different according to different implantation positions of cavities.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (9)

1. The linear plastic deformation radiation device is characterized by comprising a memory alloy tube and a silver wire arranged in the memory alloy tube, wherein radioactive nuclide is plated on the silver wire.

2. The plastically wire-deformed radiation device according to claim 1, wherein the memory alloy tube is made of nitinol.

3. The linear plastically deformable radiation device according to claim 1, wherein the memory alloy tube is a linear or helical memory alloy tube.

4. The linear plastically deformable radiation device according to claim 1, wherein the radionuclide is intermittently or continuously distributed on the silver wire.

5. The linear plastically deformable radiation device according to claim 1, wherein the silver wire is provided with a shielding material so that the radionuclide is discontinuously distributed on the silver wire.

6. The wire-like plastically deformable radiation source of claim 4, wherein said radionuclide is distributed on said silver wire in a uniform discontinuous distribution.

7. The linear plastically deformable radiation device according to claim 4, wherein the shielding material is polyimide.

8. The linear plastically deformable radiation source of claim 1, wherein said radionuclide is selected from the group consisting of iodine-125, palladium-103, holmium-166, cesium-131, and gold-198.

9. The linear plastically deformable radiation device according to claim 1, wherein both ends of the memory alloy tube are sealed by welding.

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