CN115605494A - 多聚体t细胞调节多肽及其使用方法 - Google Patents

多聚体t细胞调节多肽及其使用方法 Download PDF

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CN115605494A
CN115605494A CN202180033837.4A CN202180033837A CN115605494A CN 115605494 A CN115605494 A CN 115605494A CN 202180033837 A CN202180033837 A CN 202180033837A CN 115605494 A CN115605494 A CN 115605494A
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polypeptide
amino acid
immunomodulatory
tmmp
mhc
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李知炫
柳洙浄
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LG Chem Ltd
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LG Chem Ltd
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    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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CN202180033837.4A 2020-05-12 2021-05-11 多聚体t细胞调节多肽及其使用方法 Pending CN115605494A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063023840P 2020-05-12 2020-05-12
US63/023,840 2020-05-12
US202063041506P 2020-06-19 2020-06-19
US63/041,506 2020-06-19
PCT/KR2021/005913 WO2021230638A1 (en) 2020-05-12 2021-05-11 Multimeric t-cell modulatory polypeptides and methods of use thereof

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CN115605494A true CN115605494A (zh) 2023-01-13

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CN202180033837.4A Pending CN115605494A (zh) 2020-05-12 2021-05-11 多聚体t细胞调节多肽及其使用方法

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US (1) US20230241192A1 (https=)
EP (1) EP4149953A4 (https=)
JP (1) JP2023525822A (https=)
KR (1) KR20230009391A (https=)
CN (1) CN115605494A (https=)
AU (1) AU2021271778B2 (https=)
CA (1) CA3178427A1 (https=)
TW (1) TW202208396A (https=)
WO (1) WO2021230638A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150150975A1 (en) * 2012-07-02 2015-06-04 Sumitomo Dainippon Pharma Co., Ltd. Transdermal cancer antigen peptide preparation
TW201930337A (zh) * 2018-01-09 2019-08-01 美商信號生物製藥公司 多聚體ｔ細胞調節多肽及其使用方法
WO2020071551A1 (ja) * 2018-10-05 2020-04-09 株式会社癌免疫研究所 良性腫瘍の予防または治療薬

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106682A1 (ja) * 2002-06-12 2003-12-24 中外製薬株式会社 Ｈｌａ−ａ２４拘束性癌抗原ペプチド
WO2015195531A2 (en) * 2014-06-18 2015-12-23 Albert Einstein College Of Medicine, Inc. Syntac polypeptides and uses thereof
ES2805094T3 (es) * 2014-12-11 2021-02-10 Int Inst Cancer Immunology Inc Inmunoterapia WT1 para enfermedad angiogénica intraocular
CN107921106B (zh) * 2015-05-20 2023-09-08 住友制药株式会社 Wt1抗原肽和免疫调节剂的组合用途
EP3678691A4 (en) * 2017-09-07 2021-06-09 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
JP2020534352A (ja) * 2017-09-07 2020-11-26 キュー バイオファーマ，インコーポレーテッド コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法
TWI856047B (zh) * 2018-12-19 2024-09-21 美商信號生物製藥公司 多聚體ｔ細胞調節多肽及其使用方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150150975A1 (en) * 2012-07-02 2015-06-04 Sumitomo Dainippon Pharma Co., Ltd. Transdermal cancer antigen peptide preparation
TW201930337A (zh) * 2018-01-09 2019-08-01 美商信號生物製藥公司 多聚體ｔ細胞調節多肽及其使用方法
WO2020071551A1 (ja) * 2018-10-05 2020-04-09 株式会社癌免疫研究所 良性腫瘍の予防または治療薬

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CA3178427A1 (en) 2021-11-18
TW202208396A (zh) 2022-03-01
US20230241192A1 (en) 2023-08-03
EP4149953A4 (en) 2024-06-26
KR20230009391A (ko) 2023-01-17
JP2023525822A (ja) 2023-06-19
EP4149953A1 (en) 2023-03-22
AU2021271778B2 (en) 2025-10-23
AU2021271778A1 (en) 2022-12-08
WO2021230638A1 (en) 2021-11-18

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