CN115584313A - Detection kit for detecting infectious agent sample - Google Patents
Detection kit for detecting infectious agent sample Download PDFInfo
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- CN115584313A CN115584313A CN202211578042.4A CN202211578042A CN115584313A CN 115584313 A CN115584313 A CN 115584313A CN 202211578042 A CN202211578042 A CN 202211578042A CN 115584313 A CN115584313 A CN 115584313A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention discloses a detection kit for detecting an infectious agent sample, and belongs to the technical field of detection kits. A detection kit for detecting an infectious agent sample comprises a box body and a box cover connected to the box body through a hinge, wherein a support column is fixedly connected in the box body, the top of the support column is connected with a support plate, a detection disc is arranged on the support plate, an electric push rod is further arranged in the box body, the top of the electric push rod is connected with a positioning ring, a placing pipe which is uniformly distributed in the circumferential direction is arranged on the positioning ring, a reagent pipe is arranged in the placing pipe, a liquid source shell is rotatably arranged at the top of the box body, and a rotating pipe is movably arranged at the bottom of the liquid source shell; the invention is convenient to use, does not need to manually add reagents or transfer the reagents one by using a burette, reduces the labor intensity of operators, improves the detection efficiency, reduces the intervention of personnel, greatly reduces the probability of leakage or pollution of a detected sample, and further improves the accuracy of detection.
Description
Technical Field
The invention relates to the technical field of detection kits, in particular to a detection kit for detecting infectious pathogen samples.
Background
Intestinal diseases are diseases with high morbidity at present, infectious pathogens are easily generated in intestinal tracts, and if the intestinal diseases are not treated timely, the intestinal diseases not only easily harm the health of patients, but also easily harm the health of other people. With the development of medical and chemical industries, some detection kits which are convenient to use are rapidly popularized and used for detecting pathogen samples of infectious diseases.
The existing reagent kit generally needs to add reagents into test tubes located in the reagent kit one by one through manual operation of testers, the operation process is slow, then after a sample to be detected and the reagents are mixed in a reagent tube, the mixed reagents need to be transferred to detection test paper by adopting a pipettor or an injector for detection, when different reagents are extracted, the suction head of the pipettor needs to be replaced or the injector and the needle head need to be cleaned, the operation is complex, the time is wasted, and the detection efficiency is low; meanwhile, the process of transferring the detection sample from the reagent tube to the detection test paper requires manual operation, and if the operation is not proper, the conditions of sample leakage, sample cross contamination and the like can be generated, so that risks are brought to detection personnel and a safety belt of the detection sample, and the accuracy of the detection sample is reduced.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a detection kit for detecting an infectious agent sample.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a detect reagent box for infectious etiological agent sample detects, includes box body and the lid of hinged joint on the box body, fixedly connected with support column in the box body, the top of support column is connected with the backup pad, be provided with the detection dish in the backup pad, the inside electric putter that still is provided with of box body, electric putter's top is connected with the holding ring, be provided with on the holding ring and be circumference evenly distributed's the pipe of placing, it is provided with the reagent pipe to place the intraductal reagent pipe that is provided with, the top of box body is rotated and is set up the liquid source casing, the bottom activity of liquid source casing is provided with the rotating-tube, rotating-tube outside cover is equipped with the clear water casing, be provided with the liquid feeding pipeline between clear water casing and the reagent pipe.
Preferably, the top of box body is provided with first motor, the output of first motor passes the box body and links to each other with the liquid source casing, be connected with first connecting rod between clear water casing and the holding ring, set up the first shrinkage pool of matched with on liquid feeding pipeline and the liquid source casing, the reagent pipe is arranged in to the one end that the clear water casing was kept away from to the liquid feeding pipeline.
Preferably, the first connecting rod comprises two L-shaped rods, the two L-shaped rods are respectively connected with the clean water shell and the positioning ring, and a connecting pipe is arranged between the two L-shaped rods in a sliding mode.
Preferably, sliding connection has the piston board in the rotating tube, be formed with working cavity between the diapire of piston board and liquid source casing, be provided with feed liquor valve and the liquid valve of being connected with working cavity on rotating tube and the piston board respectively, liquid valve department is connected with flexible pipe, the upside of detection dish is arranged in to flexible pipe, set up a plurality of second shrinkage pools with feed liquor valve matched with on the clear water casing, second shrinkage pool and first shrinkage pool staggered distribution, and be circumference evenly distributed on the clear water casing.
Preferably, the supporting plate is connected with a positioning ring through a connecting rod, the positioning ring is fixedly connected with a telescopic pipe, the telescopic pipe comprises a sleeve fixedly connected with the positioning ring and a movable pipe fixedly connected with a piston plate, and the movable pipe is slidably connected in the sleeve.
Preferably, be provided with in the backup pad and be used for driving the rotatory actuating mechanism of rotating tube, actuating mechanism sets up the dwang in the backup pad including rotating, be connected with incomplete gear on the dwang, the meshing of incomplete gear outside is connected with first gear, be provided with first bull stick between first gear and the backup pad, the meshing of first gear outside is provided with first ring gear, first ring gear passes through branch and links to each other with the rotating tube, actuating mechanism is still including setting firmly the second motor in the backup pad, the output of second motor passes the backup pad and links to each other with the dwang.
Preferably, a liquid discharging mechanism is arranged in the rotating pipe and connected with a driving mechanism, the liquid discharging mechanism comprises a second rotating rod which is rotatably arranged on a supporting plate, a second gear which is meshed with the incomplete gear is arranged on the second rotating rod, a first bevel gear is arranged on the second rotating rod, a supporting plate is fixedly arranged on the supporting plate, a third rotating rod is rotatably connected onto the supporting plate, a second bevel gear which is meshed with the first bevel gear is connected onto the third rotating rod, a first connecting plate is connected onto the third rotating rod, a second connecting plate is rotatably connected onto the first connecting plate through a pin shaft, and one end, far away from the first connecting plate, of the second connecting plate is movably connected with the piston plate.
Preferably, the rotating rod is provided with a driving gear, the supporting plate is provided with a second gear ring in meshed connection with the driving gear, and the detection disc is arranged on the second gear ring.
Preferably, the detection disc is provided with a plurality of detection grooves and waste water grooves which are distributed in a circumferential staggered manner, the detection grooves are internally provided with detection test paper, and the detection grooves are provided with colorimetric marks.
Preferably, fixedly connected with shell on the holding ring, swing joint has universal ball in the shell, universal ball passes through the connecting rod and places the pipe and link to each other, the liquid source casing outside is provided with the second connecting rod, the one end that the liquid source casing was kept away from to the second connecting rod is connected with the swivel becket, be provided with a plurality of lugs that are circumference evenly distributed on the swivel becket, the lug offsets with placing the pipe activity.
Compared with the prior art, the invention provides a detection kit for detecting the pathogen sample of the infectious disease, which has the following beneficial effects:
1. this a detect reagent box for infectious agents sample detects, through making the intraductal reagent liquid source that evenly adds of every reagent, reagent and sample mix, control actuating mechanism and flowing back mechanism operation afterwards, extract one by one the reagent solution of mixing in the reagent pipe, and make it arrange in the test tray and detect, need not operating personnel and add or absorb the reagent with burette manual one by one, reduce operating personnel intensity of labour, improve detection efficiency, reduce personnel's intervention simultaneously, greatly reduced the probability that the detection sample leaks or pollutes, thereby the rate of accuracy of detection has been improved.
2. According to the detection kit for detecting the infectious etiologic agent sample, when the liquid inlet valve is aligned with the liquid adding pipeline, the piston plate is controlled to move downwards, so that the piston plate extracts the mixed reagent in the reagent tube through the liquid inlet valve and the liquid adding pipeline, the mixed reagent enters the working cavity, then the piston plate is controlled to move upwards, the mixed reagent entering the working cavity falls on the detection plate through the liquid outlet valve and the telescopic tube, and the mixed reagent is detected; when feed liquor valve and second shrinkage pool were aligned, the piston board move down can extract the inside clear water of clear water casing and get into the working chamber, when the piston board shifts up again, the clear water that gets into in the working chamber is discharged through going out the liquid valve to wash the reagent of flexible pipe inside adhesion before, avoid influencing the testing result of follow-up other sample reagents.
3. The detection kit for detecting the infectious etiologic agent sample is characterized in that when the rotating rod rotates, the driving tooth on the outer side is meshed with the second gear ring on the supporting plate, the second gear ring drives the detection plate to continuously rotate, so that the detection groove and the waste water groove which are arranged on the lower side of the telescopic pipe are automatically replaced, and the mixed reagent falling from the telescopic pipe and the waste water after the telescopic pipe is cleaned respectively enter the detection groove and the waste water groove.
4. This a detect reagent box for infectious agents sample detects, the rotation of liquid source casing can drive the swivel becket through the second connecting rod and rotate, the inboard lug that sets up during the swivel becket rotation offsets with placing the pipe, it swings on the holding ring through universal ball to place the pipe, when the lug no longer with place the pipe and offset, it resets automatically under the solution gravity of its inside reagent pipe to place the pipe, thereby rock when making the intraductal sample of reagent add the reagent, accelerate its mixing efficiency and the homogeneity of mixing, and then improve detection efficiency and the testing result to the sample.
Drawings
FIG. 1 is a first schematic structural diagram of the present invention;
FIG. 2 is a second schematic structural view of the present invention;
FIG. 3 is a first schematic structural diagram of the interior of the case according to the present invention;
FIG. 4 is a schematic cross-sectional view of the present invention;
FIG. 5 is an enlarged view of a portion A of FIG. 4 according to the present invention;
FIG. 6 is an enlarged view of the portion B of FIG. 4 according to the present invention;
FIG. 7 is a schematic sectional view of the clean water housing of the present invention;
FIG. 8 is a second schematic view of the inner structure of the case according to the present invention;
FIG. 9 is an external view of the support plate of the present invention;
FIG. 10 is a cross-sectional view of the support plate of the present invention;
fig. 11 is a schematic structural diagram of the detection tray of the present invention.
In the figure: 1. a case body; 101. a support pillar; 102. an electric push rod; 2. a box cover; 3. a support plate; 4. detecting a disc; 401. a detection tank; 402. a wastewater tank; 403. a colorimetric mark; 5. a positioning ring; 501. a housing; 502. a universal ball; 6. placing a tube; 7. a reagent tube; 8. a liquid source housing; 801. a first motor; 802. a first recess; 9. rotating the tube; 901. a liquid inlet valve; 902. a liquid outlet valve; 10. a clean water shell; 1001. a second recess; 11. a first link; 111. an L-shaped rod; 112. a connecting pipe; 12. a liquid feeding pipe; 13. a piston plate; 14. a telescopic pipe; 141. a sleeve; 142. a movable tube; 15. rotating the rod; 151. an incomplete gear; 152. a second motor; 153. a driving gear; 16. a first rotating lever; 161. a first gear; 17. a first ring gear; 18. a second rotating lever; 181. a second gear; 182. a first bevel gear; 19. a support plate; 191. a third rotating rod; 1911. a first connecting plate; 1912. a second connecting plate; 192. a second bevel gear; 20. a second ring gear; 21. positioning rings; 22. a rotating ring; 221. a second link; 222. and (4) a bump.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example 1:
referring to fig. 1, fig. 2, fig. 3, fig. 4, fig. 7, fig. 8 and fig. 11, a detection kit for detecting infectious etiologic agent samples, including a box body 1 and a box cover 2 hinged on the box body 1, a support column 101 is fixedly connected in the box body 1, a support plate 3 is connected to the top of the support column 101, a detection disc 4 is arranged on the support plate 3, an electric push rod 102 is further arranged inside the box body 1, a positioning ring 5 is connected to the top of the electric push rod 102, a placing tube 6 which is circumferentially and uniformly distributed is arranged on the positioning ring 5, a reagent tube 7 is arranged in the placing tube 6, a liquid source housing 8 is rotatably arranged at the top of the box body 1, a rotating tube 9 is movably arranged at the bottom of the liquid source housing 8, a clean water housing 10 is sleeved outside the rotating tube 9, and a liquid adding pipeline 12 is arranged between the clean water housing 10 and the reagent tube 7.
Specifically, there are different testing samples in a plurality of reagent pipes 7 in the box body 1, cooperate with liquid feeding pipeline 12 through control liquid source casing 8, make evenly add the reagent liquid source in every reagent pipe 7, reagent and sample mix, extract one by one the reagent solution of mixing in the reagent pipe 7 afterwards, and make it arrange in and detect in detecting tray 4 and detect, need not operating personnel and use burette manual joining one by one or absorb reagent, reduce operating personnel intensity of labour, improve detection efficiency, reduce personnel's intervention simultaneously, greatly reduced the probability that the testing sample leaked or polluted, thereby the accuracy of detection has been improved.
Example 2:
referring to fig. 2, fig. 3, fig. 4, fig. 5 and fig. 7, a detection kit for detecting an infectious agent sample, based on embodiment 1, further, a first motor 801 is disposed on a top of the box body 1, an output end of the first motor 801 passes through the box body 1 and is connected to the liquid source housing 8, a first connecting rod 11 is connected between the clean water housing 10 and the positioning ring 5, a first concave hole 802 matched with the liquid source housing 8 is disposed on the liquid feeding pipe 12, and an end of the liquid feeding pipe 12 away from the clean water housing 10 is disposed in the reagent tube 7.
Specifically, through controlling the operation of first motor 801, make the output of first motor 801 drive liquid source casing 8 at the internal rotation of box body 1, a first shrinkage pool 802 has been seted up to the inside of liquid source casing 8, a first shrinkage pool 802 has also been seted up in a plurality of liquid feeding pipeline 12 that set up on clear water casing 10, along with liquid source casing 8 at the uniform velocity rotation on clear water casing 10, reagent in the liquid source casing 8 falls through first shrinkage pool 802, and get into in every liquid feeding pipeline 12 one by one, finally fall into in reagent pipe 7 under the action of gravity, mix with the detection sample in the reagent pipe 7.
Example 3:
referring to fig. 3, 4, 5 and 8, in addition to embodiment 2, the first connecting rod 11 includes two L-shaped rods 111, the two L-shaped rods 111 are respectively connected to the clean water housing 10 and the positioning ring 5, and a connecting pipe 112 is slidably disposed between the two L-shaped rods 111.
Specifically, by controlling the electric push rod 102 to contract, the electric push rod 102 drives the positioning ring 5 to move downwards, so that the positioning ring 5 drives the placing pipe 6 and the reagent pipe 7 inside the placing pipe to move downwards, the height of the clear water shell 10 movably arranged with the liquid source shell 8 is kept unchanged, the first connecting rod 11 is automatically stretched, the reagent pipe 7 is conveniently kept away from the liquid adding pipeline 12, and the reagent pipe 7 is taken out and cleaned.
Example 4:
referring to fig. 2, 3, 4, 5, 7 and 9, in addition to embodiment 2, a piston plate 13 is slidably connected to the rotation tube 9, a working cavity is formed between the piston plate 13 and the bottom wall of the liquid source housing 8, a liquid inlet valve 901 and a liquid outlet valve 902 connected to the working cavity are respectively disposed on the rotation tube 9 and the piston plate 13, a telescopic tube 14 is connected to the liquid outlet valve 902, the telescopic tube 14 is disposed on the upper side of the detection plate 4, a plurality of second concave holes 1001 matching with the liquid inlet valve 901 are disposed on the clean water housing 10, the second concave holes 1001 and the first concave holes 802 are distributed in a staggered manner, and are circumferentially and uniformly distributed on the clean water housing 10.
Specifically, when the liquid inlet valve 901 is aligned with the liquid adding pipeline 12, the piston plate 13 is controlled to move downwards, so that the piston plate 13 extracts the mixed reagent in the reagent tube 7 through the liquid inlet valve 901 and the liquid adding pipeline 12, the mixed reagent enters the working cavity, and then the piston plate 13 is controlled to move upwards, so that the mixed reagent entering the working cavity falls on the detection disc 4 through the liquid outlet valve 902 and the telescopic tube 14, and the mixed reagent is detected; when the liquid inlet valve 901 is aligned with the second concave hole 1001, the downward movement of the piston plate 13 can draw the clean water in the clean water shell 10 into the working cavity, and when the piston plate 13 moves upward again, the clean water entering the working cavity is discharged through the liquid outlet valve 902, and the reagent adhered to the inside of the telescopic pipe 14 is washed, so that the subsequent detection results of other sample reagents are prevented from being influenced.
Example 5:
referring to fig. 4 and fig. 8, in addition to embodiment 4, a positioning ring 21 is connected to the supporting plate 3 through a connecting rod, the positioning ring 21 is fixedly connected to the telescopic tube 14, the telescopic tube 14 includes a sleeve 141 fixedly connected to the positioning ring 21 and a movable tube 142 fixedly connected to the piston plate 13, and the movable tube 142 is slidably connected to the sleeve 141.
Specifically, the sleeve 141 of the extension tube 14 is fixed by the positioning ring 21 as the piston plate 13 moves up and down, and the movable tube 142 slides in the sleeve 141 as the piston plate 13 moves up and down.
Example 6:
referring to fig. 2, 3, 4, 5, 6, 7, 8, 9 and 10, in embodiment 4, a driving mechanism for driving the rotation tube 9 to rotate is further disposed on the supporting plate 3, the driving mechanism includes a rotation rod 15 rotatably disposed on the supporting plate 3, an incomplete gear 151 is connected to the rotation rod 15, a first gear 161 is engaged and connected to an outer side of the incomplete gear 151, a first rotation rod 16 is disposed between the first gear 161 and the supporting plate 3, a first gear ring 17 is engaged and disposed on an outer side of the first gear 161, the first gear ring 17 is connected to the rotation tube 9 through a support rod, the driving mechanism further includes a second motor 152 fixedly disposed on the supporting plate 3, and an output end of the second motor 152 passes through the supporting plate 3 and is connected to the rotation rod 15.
Specifically, through controlling the operation of second motor 152, it is rotatory to make the output of second motor 152 drive dwang 15, it rotates to drive incomplete gear 151 when dwang 15 is rotatory, incomplete gear 151 rotates with first gear 161 intermittent type nature meshing on the first dwang 16 when rotating, make first gear 161 and 17 intermittent type nature meshing of first ring gear, it is rotatory to drive rotating tube 9 through branch when first ring gear 17 rotates, and then make the second shrinkage pool 1001 on the opening of feed liquor valve 901 on the rotating tube 9 and liquid feeding pipeline 12 or the clear water casing 10 align, be convenient for extract the use to mixed reagent or clear water.
Example 7:
referring to fig. 2, 3, 4, 5, 6, 7, 8, 9 and 10, in example 6, further, a liquid discharging mechanism is disposed in the rotating tube 9, the liquid discharging mechanism is connected to a driving mechanism, the liquid discharging mechanism includes a second rotating rod 18 rotatably disposed on the supporting plate 3, a second gear 181 engaged with the incomplete gear 151 is disposed on the second rotating rod 18, a first bevel gear 182 is disposed on the second rotating rod 18, a supporting plate 19 is fixedly disposed on the supporting plate 3, a third rotating rod 191 is rotatably connected to the supporting plate 19, a second bevel gear 192 engaged with the first bevel gear 182 is connected to the third rotating rod 191, a first connecting plate 1911 is connected to the third rotating rod 191, a second connecting plate 1912 is rotatably connected to the first connecting plate 1911 through a pin, and one end of the second connecting plate 1912, which is far away from the first connecting plate 1911, is movably connected to the piston plate 13.
Specifically, the incomplete gear 151 is driven to rotate when the rotating rod 15 rotates, after the incomplete gear 151 is completely meshed with the first gear 161 on the first rotating rod 16, the first gear 161 does not rotate any more, at this time, the incomplete gear 151 is meshed with the second gear 181 on the second rotating rod 18, the second gear 181 rotates to drive the second rotating rod 18 and the first bevel gear 182 outside to rotate, the first bevel gear 182 is meshed with the second bevel gear 192 on the third rotating rod 191, so that the second bevel gear 192 drives the third rotating rod 191 to rotate, the third rotating rod 191 drives the first connecting plate 1911 to rotate when rotating, the first connecting plate 1911 drives the second connecting plate 1912 to swing, and the second connecting plate 1912 further pulls the piston plate 13 to reciprocate up and down in the rotating tube 9.
Example 8:
referring to fig. 2, 3, 9, 10 and 11, in example 7, a driving gear 153 is provided on the rotating shaft 15, a second gear ring 20 engaged with the driving gear 153 is provided on the supporting plate 3, and a detection plate 4 is provided on the second gear ring 20.
Furthermore, a plurality of detection grooves 401 and waste water grooves 402 which are distributed in a circumferential staggered manner are formed in the detection disc 4, detection test paper is arranged in the detection grooves 401, and colorimetric marks 403 are arranged at the positions of the detection grooves 401.
Specifically, when the rotating rod 15 rotates, the driving gear 153 on the outer side is meshed with the second gear ring 20 on the supporting plate 3, the second gear ring 20 drives the detection disc 4 to continuously rotate, so that the mixed reagent falling from the telescopic tube 14 and the wastewater after cleaning the telescopic tube 14 respectively enter the detection groove 401 and the wastewater groove 402, the mixed reagent after entering the detection groove 401 contacts with the internal detection test paper, and the color of the mixed reagent is compared with the corresponding colorimetric mark 403 after changing the color, so that the use is convenient; it should be noted that the detection plate 4 may be composed of two semicircular plates, so that the detection plate 4 can be conveniently taken from or placed on the second ring gear 20.
Example 9:
referring to fig. 2, fig. 3, fig. 4 and fig. 8, in addition to embodiment 2, a casing 501 is fixedly connected to the positioning ring 5, a universal ball 502 is movably connected to the casing 501, the universal ball 502 is connected to the placing tube 6 through a connecting rod, a second connecting rod 221 is disposed outside the liquid source casing 8, a rotating ring 22 is connected to an end of the second connecting rod 221 away from the liquid source casing 8, a plurality of protrusions 222 are uniformly distributed on the rotating ring 22, and the protrusions 222 movably abut against the placing tube 6.
Specifically, when liquid source casing 8 evenly pours into reagent into every reagent pipe 7, liquid source casing 8's rotation can drive swivel 22 through second connecting rod 221 and rotate, inboard lug 222 that sets up when swivel 22 rotates offsets with placing pipe 6, it swings on holding ring 5 through universal ball 502 to place pipe 6, when lug 222 no longer with place pipe 6 and offset, place pipe 6 automatic re-setting under the solution gravity of its inside reagent pipe 7, thereby it rocks when reagent is added to the sample in reagent pipe 7, accelerate its mixing efficiency and the homogeneity of mixing, and then improve detection efficiency and the testing result to the sample, it needs to explain, it is less to place the range that pipe 6 atress rocked, can not collide with inside liquid feeding pipeline 12 when making reagent pipe 7 rock along with placing pipe 6, cause the damage of reagent pipe 7.
The working principle is as follows: different detection samples are stored in a plurality of reagent tubes 7 in the box body 1, a liquid source shell 8 is driven by an output end of a first motor 801 to rotate in the box body 1, a first concave hole 802 is formed in the liquid source shell 8, a first concave hole 802 is also formed in a plurality of liquid adding pipelines 12 arranged on the clean water shell 10, along with the uniform rotation of the liquid source shell 8 on the clean water shell 10, reagents in the liquid source shell 8 fall through the first concave hole 802 and enter each liquid adding pipeline 12 one by one, finally fall into the reagent tubes 7 under the action of gravity and are mixed with the detection samples in the reagent tubes 7, so that the reagent liquid sources are uniformly added into each reagent tube 7, in the process, the rotation of the liquid source shell 8 drives the rotating ring 22 to rotate through the second connecting rod 221, a lug 222 arranged on the inner side of the rotating ring 22 abuts against the placing tube 6 when the rotating ring 22 rotates, the placing tube 6 swings on the positioning ring 5 through the universal ball 502, so that the samples in the reagent tubes 7 swing when the reagents are added, the mixing efficiency and the mixing uniformity are accelerated, and the detection results of the samples are improved; then, the driving mechanism and the liquid discharging mechanism are controlled to work together, and it should be noted that at this time, the first concave hole 802 of the liquid source shell 8 is no longer opposite to the first concave hole 802 of the liquid feeding pipeline 12; by controlling the operation of the second motor 152, the output end of the second motor 152 drives the rotating rod 15 to rotate, the rotating rod 15 drives the incomplete gear 151 to rotate when rotating, the incomplete gear 151 intermittently engages with the first gear 161 on the first rotating rod 16 when rotating, so that the first gear 161 intermittently engages with the first gear ring 17, the first gear ring 17 drives the rotating tube 9 to rotate through the supporting rod when rotating, so that the liquid inlet valve 901 on the rotating tube 9 is aligned with the opening of the liquid adding pipeline 12, the incomplete gear 151 no longer engages with the first gear 161 with the continuous rotation of the rotating rod 15, at this time, the incomplete gear 151 engages with the second gear 181, so that the second rotating rod 18 and the first bevel gear 182 on the outer side are driven to rotate when rotating the second gear 181, the first bevel gear 182 engages with the second bevel gear 192 on the third rotating rod 191, so that the second bevel gear 192 drives the third rotating rod 191 to rotate, the first connecting plate 1911 drives the second connecting plate 1912 to swing, so that the second connecting plate 1912 pulls the piston plate 13 in the rotating rod 9 to move up and down, so that the piston plate moves to control the piston plate to enter the liquid adding and mixing chamber through the mixing valve 902, and the mixing chamber 401 to control the liquid adding reagent flowing through the mixing valve 401 and the mixing chamber 401; then, the incomplete gear 151 is meshed with the first gear 161 again, so that the rotating pipe 9 continuously rotates and is aligned with the second concave hole 1001 of the clean water housing 10 through the liquid inlet valve 901, then, the incomplete gear 151 is meshed with the second gear 181 again, the piston plate 13 is controlled to move up and down, the piston plate 13 moves down to pump clean water in the clean water housing 10 into the working cavity, when the piston plate 13 moves up again, the clean water in the working cavity is discharged through the liquid outlet valve 902, and the reagent adhered to the interior of the extension tube 14 is washed, so that the detection result of other subsequent sample reagents is prevented from being influenced, the driving gear 153 on the outer side is meshed with the second gear ring 20 on the support plate 3 when the rotating rod 15 rotates, the second gear ring 20 drives the detection disc 4 to continuously rotate, the detection groove 401 originally arranged on the lower side of the extension tube 14 is automatically replaced by the waste water groove 402, and the washed waste water falls into the waste water groove 402 from the extension tube 14. This application convenient operation need not operating personnel and adds or absorb reagent with buret manual one by one, reduces operating personnel intensity of labour, improves detection efficiency, reduces personnel's intervention simultaneously, has greatly reduced the probability that the sample detected leaks or pollutes to the rate of accuracy of detecting has been improved.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (10)
1. The utility model provides a detect reagent box for infectious etiological agent sample detects, includes box body (1) and box cover (2) of hinged joint on box body (1), its characterized in that, fixedly connected with support column (101) in box body (1), the top of support column (101) is connected with backup pad (3), be provided with on backup pad (3) and detect dish (4), box body (1) inside still is provided with electric putter (102), the top of electric putter (102) is connected with holding ring (5), be provided with on holding ring (5) and place pipe (6) that are circumference evenly distributed, it is provided with reagent pipe (7) in pipe (6) to place, the top of box body (1) is rotated and is set up liquid source casing (8), the bottom activity of liquid source casing (8) is provided with rotating tube (9), rotating tube (9) outside cover is equipped with clear water casing (10), be provided with liquid feeding pipeline (12) between clear water casing (10) and reagent pipe (7).
2. The detection kit for detecting the sample of the infectious etiologic agent according to claim 1, wherein a first motor (801) is disposed on the top of the case (1), an output end of the first motor (801) passes through the case (1) and is connected to the liquid source housing (8), a first connecting rod (11) is connected between the clean water housing (10) and the positioning ring (5), a first concave hole (802) matched with the liquid source housing (8) is formed in the liquid feeding pipeline (12), and one end of the liquid feeding pipeline (12) far away from the clean water housing (10) is disposed in the reagent tube (7).
3. The detection kit for the detection of an infectious agent sample according to claim 2, wherein the first connecting rod (11) comprises two L-shaped rods (111), the two L-shaped rods (111) are respectively connected with the clear water housing (10) and the positioning ring (5), and a connecting pipe (112) is slidably arranged between the two L-shaped rods (111).
4. The detection kit for detecting the pathogen samples according to claim 2, wherein a piston plate (13) is slidably connected to the rotation tube (9), a working cavity is formed between the piston plate (13) and the bottom wall of the liquid source housing (8), a liquid inlet valve (901) and a liquid outlet valve (902) connected to the working cavity are respectively disposed on the rotation tube (9) and the piston plate (13), a telescopic tube (14) is connected to the liquid outlet valve (902), the telescopic tube (14) is disposed on the upper side of the detection disc (4), a plurality of second concave holes (1001) matched with the liquid inlet valve (901) are disposed on the clean water housing (10), and the second concave holes (1001) and the first concave holes (802) are distributed in a staggered manner and are circumferentially and uniformly distributed on the clean water housing (10).
5. The detection kit for detecting the sample of the infectious etiologic agent according to claim 4, wherein said supporting plate (3) is connected with a positioning ring (21) through a connecting rod, said positioning ring (21) is fixedly connected with a telescopic tube (14), said telescopic tube (14) comprises a sleeve (141) fixedly connected with said positioning ring (21) and a movable tube (142) fixedly connected with said piston plate (13), said movable tube (142) is slidably connected in said sleeve (141).
6. The detection kit for detecting the pathogen sample of the infectious agent according to claim 4, wherein a driving mechanism for driving the rotation tube (9) to rotate is arranged on the support plate (3), the driving mechanism comprises a rotating rod (15) rotatably arranged on the support plate (3), an incomplete gear (151) is connected on the rotating rod (15), a first gear (161) is engaged and connected to the outer side of the incomplete gear (151), a first rotating rod (16) is arranged between the first gear (161) and the support plate (3), a first gear ring (17) is engaged and arranged on the outer side of the first gear (161), the first gear ring (17) is connected to the rotation tube (9) through a supporting rod, the driving mechanism further comprises a second motor (152) fixedly arranged on the support plate (3), and the output end of the second motor (152) passes through the support plate (3) and is connected to the rotating rod (15).
7. The detection kit for detecting the sample of the infectious etiologic agent according to claim 6, wherein a drainage mechanism is disposed in the rotating tube (9), the drainage mechanism is connected to the driving mechanism, the drainage mechanism comprises a second rotating rod (18) rotatably disposed on the supporting plate (3), a second gear (181) engaged with the incomplete gear (151) is disposed on the second rotating rod (18), a first bevel gear (182) is disposed on the second rotating rod (18), a supporting plate (19) is fixedly disposed on the supporting plate (3), a third rotating rod (191) is rotatably connected to the supporting plate (19), a second bevel gear (192) engaged with the first bevel gear (182) is connected to the third rotating rod (191), a first connecting plate (1911) is connected to the third rotating rod (191), a second connecting plate (1912) is rotatably connected to the first connecting plate (1911) through a pin shaft, and one end of the second connecting plate (1912) far away from the first connecting plate (1911) is movably connected to the piston plate (13).
8. The detection kit for detecting the sample of the infectious agent according to claim 7, wherein the rotating rod (15) is provided with a driving gear (153), the supporting plate (3) is provided with a second gear ring (20) engaged with the driving gear (153), and the detection plate (4) is disposed on the second gear ring (20).
9. The detection kit for detecting the infectious agent sample according to claim 8, wherein the detection tray (4) is provided with a plurality of detection grooves (401) and waste water grooves (402) which are circumferentially staggered, the detection grooves (401) are internally provided with detection test paper, and the detection grooves (401) are provided with colorimetric marks (403).
10. The detection kit for detecting the infectious agent sample according to claim 2, wherein a housing (501) is fixedly connected to the positioning ring (5), a universal ball (502) is movably connected to the housing (501), the universal ball (502) is connected to the placing tube (6) through a connecting rod, a second connecting rod (221) is arranged outside the liquid source housing (8), a rotating ring (22) is connected to one end of the second connecting rod (221) away from the liquid source housing (8), a plurality of protrusions (222) are uniformly distributed on the rotating ring (22), and the protrusions (222) are movably abutted against the placing tube (6).
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| CN202211578042.4A CN115584313B (en) | 2022-12-09 | 2022-12-09 | Detection kit for detecting infectious pathogen sample |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN118146932A (en) * | 2024-05-08 | 2024-06-07 | 山东大学齐鲁医院德州医院(德州市人民医院) | Lung cancer detection kit |
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| CN115584313B (en) | 2023-07-28 |
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