CN115581714A - Externally-applied ointment for treating whelk and preparation method thereof - Google Patents
Externally-applied ointment for treating whelk and preparation method thereof Download PDFInfo
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- CN115581714A CN115581714A CN202211495580.7A CN202211495580A CN115581714A CN 115581714 A CN115581714 A CN 115581714A CN 202211495580 A CN202211495580 A CN 202211495580A CN 115581714 A CN115581714 A CN 115581714A
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- 239000002674 ointment Substances 0.000 title claims abstract description 43
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 206
- 229940099259 vaseline Drugs 0.000 claims abstract description 37
- 235000012907 honey Nutrition 0.000 claims abstract description 26
- 239000002994 raw material Substances 0.000 claims abstract description 24
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 22
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229910021538 borax Inorganic materials 0.000 claims abstract description 21
- 239000004328 sodium tetraborate Substances 0.000 claims abstract description 21
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 21
- 206010004542 Bezoar Diseases 0.000 claims abstract description 18
- 238000000034 method Methods 0.000 claims abstract description 18
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 17
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 17
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 17
- 229940116229 borneol Drugs 0.000 claims abstract description 17
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229940105847 calamine Drugs 0.000 claims abstract description 17
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229910052864 hemimorphite Inorganic materials 0.000 claims abstract description 17
- 239000011787 zinc oxide Substances 0.000 claims abstract description 17
- 235000014692 zinc oxide Nutrition 0.000 claims abstract description 17
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 claims abstract description 17
- JHGWQSGWUPCKNT-UHFFFAOYSA-N 2-tert-butyl-4-methyl-1,3,5-trinitrobenzene Chemical compound CC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C(C(C)(C)C)=C1[N+]([O-])=O JHGWQSGWUPCKNT-UHFFFAOYSA-N 0.000 claims abstract description 16
- 208000002874 Acne Vulgaris Diseases 0.000 claims abstract description 16
- 241000270295 Serpentes Species 0.000 claims abstract description 16
- 206010000496 acne Diseases 0.000 claims abstract description 16
- 235000019270 ammonium chloride Nutrition 0.000 claims abstract description 16
- 230000001954 sterilising effect Effects 0.000 claims description 24
- 239000004166 Lanolin Substances 0.000 claims description 22
- 229940039717 lanolin Drugs 0.000 claims description 22
- 235000019388 lanolin Nutrition 0.000 claims description 22
- 239000011812 mixed powder Substances 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 20
- 239000003814 drug Substances 0.000 abstract description 15
- 238000010521 absorption reaction Methods 0.000 abstract description 9
- 239000008280 blood Substances 0.000 abstract description 7
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- 238000002156 mixing Methods 0.000 description 6
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- 244000293323 Cosmos caudatus Species 0.000 description 5
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- 244000153234 Hibiscus abelmoschus Species 0.000 description 5
- 235000003143 Panax notoginseng Nutrition 0.000 description 5
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- 238000010298 pulverizing process Methods 0.000 description 5
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- 230000002588 toxic effect Effects 0.000 description 4
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- 201000004624 Dermatitis Diseases 0.000 description 2
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 2
- 238000011047 acute toxicity test Methods 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
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- 241000402754 Erythranthe moschata Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
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- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
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- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
- A61K35/06—Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/02—Ammonia; Compounds thereof
-
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- A61K35/10—Peat; Amber; Turf; Humus
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K35/413—Gall bladder; Bile
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61P17/10—Anti-acne agents
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Abstract
The invention relates to the technical field of external medicines, and discloses an external ointment for treating whelk and a preparation method thereof, aiming at solving the problems of poor absorption effect and poor whelk treatment effect of the existing external ointment for treating whelk in use, wherein the external ointment for treating whelk comprises the following raw materials in parts by weight: vaseline, lanoline, honey, pseudo-ginseng powder, snake gall powder, artificial bezoar powder, artificial musk powder, calamine powder, amber powder, pearl powder, borax powder, sal ammoniac powder and borneol. The externally-applied ointment for treating the whelk prepared by the invention is easy to enter tissues through skin, the absorption rate is greatly improved, and the curative effect of the medicine is improved; the invention has simple process and low cost, has good curative effect on various skin inflammatory diseases such as heat-toxin and blood stasis acne and the like, and is suitable for industrial production.
Description
Technical Field
The invention relates to the technical field of external medicines, in particular to an external ointment for treating whelk and a preparation method thereof.
Background
The acne generally refers to acne, is a chronic inflammatory dermatosis of a pilosebaceous unit, is mainly better to be developed in teenagers, is closely related to factors such as excessive sebum secretion, blockage of pilosebaceous vessels, bacterial infection, inflammatory reaction and the like, and has the problems of poor absorption effect and poor acne treatment effect when the existing external ointment for treating the acne is used.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides an external ointment for treating whelk and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
an external ointment for treating whelk comprises the following raw materials in parts by weight: 800-900 parts of vaseline, 35-45 parts of lanolin, 45-55 parts of honey, 6-8 parts of pseudo-ginseng powder, 0.5-0.7 part of snake gall powder, 0.3-0.5 part of artificial bezoar powder, 0.3-0.5 part of artificial musk powder, 30-40 parts of calamine powder, 0.12-0.18 part of amber powder, 0.3-0.5 part of pearl powder, 0.5-1.5 parts of borax powder, 0.04-0.06 part of sal ammoniac powder and 12-18 parts of borneol.
Preferably, the feed comprises the following raw materials in parts by weight: 850 parts of vaseline, 40 parts of lanolin, 50 parts of honey, 7 parts of pseudo-ginseng powder, 0.6 part of snake gall powder, 0.4 part of artificial bezoar powder, 0.4 part of artificial musk powder, 35 parts of calamine powder, 0.15 part of amber powder, 0.4 part of pearl powder, 1 part of borax powder, 0.05 part of sal ammoniac powder and 15 parts of borneol.
Preferably, the feed comprises the following raw materials in parts by weight: 845-855 parts of vaseline, 38-42 parts of lanolin, 48-52 parts of honey, 6.5-7.5 parts of pseudo-ginseng powder, 0.55-0.65 part of snake gall powder, 0.35-0.45 part of artificial bezoar powder, 0.35-0.45 part of artificial musk powder, 34-36 parts of calamine powder, 0.14-0.16 part of amber powder, 0.38-0.42 part of pearl powder, 0.9-1.1 part of borax powder, 0.05 part of sal ammoniac powder and 14-17 parts of borneol.
The preparation method of the external ointment for treating the whelk comprises the following steps:
step 1: according to the weight parts of the raw materials, grinding and sieving pseudo-ginseng powder, snake gall powder, artificial bezoar powder, artificial musk powder, calamine powder, amber powder, pearl powder, borax powder, sal ammoniac powder and borneol, and uniformly mixing to obtain mixed powder;
step 2: further crushing the mixed powder to obtain raw material powder;
and 3, step 3: sterilizing Mel, lanoline and vaseline;
and 4, step 4: and (3) fully stirring the sterilized honey, lanolin and vaseline and the raw material powder obtained in the step (2) for 60-120 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
Preferably, in the step 1, the pseudo-ginseng powder, the snake gall powder, the artificial bezoar powder, the artificial musk powder, the calamine powder, the amber powder, the pearl powder, the borax powder, the sal ammoniac powder and the borneol are crushed and sieved by a 200-mesh sieve; and in the step 2, further crushing the mixed powder by using a jet mill.
Preferably, the honey sterilization method in the step 3 comprises the following steps: placing Mel in 130-180 deg.C environment, and sterilizing for 60-90 min.
Preferably, the sterilization method of the lanolin in the step 3 comprises the following steps: placing lanolin in 130-180 deg.C environment, and sterilizing for 60-90 min.
Preferably, the sterilization method of the vaseline in the step 3 comprises the following steps: placing vaseline in an environment with the temperature controlled at 130-180 ℃, and sterilizing for 60-90 minutes; stirring until vaseline is cooled to 60-80 ℃.
The invention has the beneficial effects that:
the invention adopts a micronization process with the medicine, solves the problem of difficult absorption of the mineral medicine, and the medicine easily enters tissues through skin, so that the absorption rate is greatly improved, and the curative effect of the medicine is improved.
The invention has simple process and low cost, has good curative effect on various skin inflammatory diseases such as heat-toxin and blood stasis type acne and the like, and is suitable for industrial production.
The invention has reasonable formula, wide distribution of each medicine in the formula, rich resources, mature technical process and easy control.
Pharmacological research shows that the external ointment for treating the acne prepared by the invention has remarkable efficacies of diminishing redness and swelling of skin inflammation, has strong antibacterial and anti-inflammatory effects in vivo and in vitro, can remarkably inhibit inflammatory swelling and increase of skin capillary permeability, can remarkably improve tolerance of pain stimulation, and has good analgesic effect. The combination of pharmacokinetic research shows that the externally applied ointment for treating whelk prepared by the invention has the effects of good absorption and high bioavailability, and long-term clinical evidence shows that the externally applied ointment for treating whelk prepared by the invention has the advantages of high action speed, clear medicinal action and effects of treating both principal and secondary aspects of a disease; acute toxicity tests are carried out on the externally-applied acne treatment ointment prepared by the invention, and the tests show that the externally-applied acne treatment ointment prepared by the invention has no obvious toxic or side effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Example 1
Weighing 800 parts of vaseline, 35 parts of lanoline, 45 parts of honey, 6 parts of pseudo-ginseng powder, 0.5 part of snake gall powder, 0.3 part of artificial bezoar powder, 0.3 part of artificial musk powder, 30 parts of calamine powder, 0.12 part of amber powder, 0.3 part of pearl powder, 0.5 part of borax powder, 0.04 part of sal ammoniac powder and 12 parts of borneol;
pulverizing Notoginseng radix powder, fel Serpentis powder, artificial calculus bovis powder, artificial Moschus powder, calamina powder, succinum powder, margarita powder, borax powder, sal Ammoniacus powder, and Borneolum Syntheticum, sieving with 200 mesh sieve, and mixing to obtain mixed powder; further crushing the mixed powder to obtain raw material powder; placing honey and lanolin in an environment with the temperature controlled at 130 ℃, and sterilizing for 60 minutes; placing vaseline in an environment with the temperature controlled at 130 ℃, and sterilizing for 60 minutes; stirring until the temperature of the vaseline is reduced to 60 ℃; and (3) fully stirring the sterilized honey, lanolin and vaseline and the raw material powder obtained in the step (2) for 60 minutes until the ointment is uniform, thus obtaining the external ointment for treating the acne.
Example 2
Weighing 900 parts of vaseline, 45 parts of lanoline, 55 parts of honey, 8 parts of pseudo-ginseng powder, 0.7 part of snake gall powder, 0.5 part of artificial bezoar powder, 0.5 part of artificial musk powder, 40 parts of calamine powder, 0.18 part of amber powder, 0.5 part of pearl powder, 1.5 parts of borax powder, 0.06 part of sal ammoniac powder and 18 parts of borneol;
pulverizing Notoginseng radix powder, fel Serpentis powder, artificial calculus bovis powder, artificial Moschus powder, calamina powder, succinum powder, margarita powder, borax powder, sal Ammoniacus powder, and Borneolum Syntheticum, sieving with 200 mesh sieve, and mixing to obtain mixed powder; further crushing the mixed powder to obtain raw material powder; putting honey and lanolin into an environment with the temperature controlled at 180 ℃, and sterilizing for 90 minutes; placing vaseline in an environment with the temperature controlled at 180 ℃, and sterilizing for 90 minutes; stirring until vaseline is cooled to 80 ℃; and (3) fully stirring the sterilized honey, the lanoline and the vaseline and the raw material powder obtained in the step (2) for 120 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
Example 3
Weighing 850 parts of vaseline, 40 parts of lanoline, 50 parts of honey, 7 parts of pseudo-ginseng powder, 0.6 part of snake gall powder, 0.4 part of artificial bezoar powder, 0.4 part of artificial musk powder, 35 parts of calamine powder, 0.15 part of amber powder, 0.4 part of pearl powder, 1 part of borax powder, 0.05 part of sal ammoniac powder and 15 parts of borneol;
pulverizing Notoginseng radix powder, fel Serpentis powder, artificial bezoar powder, artificial Moschus powder, calamina powder, succinum powder, margarita powder, borax powder, sal Ammoniacus powder, and Borneolum Syntheticum, sieving with 200 mesh sieve, and mixing to obtain mixed powder; further crushing the mixed powder to obtain raw material powder; placing honey and lanolin in an environment with the temperature controlled at 155 ℃, and sterilizing for 75 minutes; placing vaseline in an environment with the temperature controlled to 155 ℃, and sterilizing for 75 minutes; stirring until vaseline is cooled to 70 ℃; and (3) fully stirring the sterilized honey, the lanoline and the vaseline and the raw material powder obtained in the step (2) for 90 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
Example 4
Weighing 845 parts of vaseline, 38 parts of lanolin, 48 parts of honey, 6.5 parts of pseudo-ginseng powder, 0.55 part of snake gall powder, 0.35 part of artificial bezoar powder, 0.35 part of artificial musk powder, 34 parts of calamine powder, 0.14 part of amber powder, 0.38 part of pearl powder, 0.9 part of borax powder, 0.05 part of sal ammoniac powder and 14 parts of borneol;
pulverizing Notoginseng radix powder, fel Serpentis powder, artificial calculus bovis powder, artificial Moschus powder, calamina powder, succinum powder, margarita powder, borax powder, sal Ammoniacus powder, and Borneolum Syntheticum, sieving with 200 mesh sieve, and mixing to obtain mixed powder; further crushing the mixed powder to obtain raw material powder; putting honey and lanolin into an environment with the temperature controlled at 135 ℃, and sterilizing for 65 minutes; placing vaseline in an environment with the temperature controlled at 135 ℃, and sterilizing for 65 minutes; stirring until vaseline is cooled to 65 ℃; and (3) fully stirring the sterilized honey, the lanoline and the vaseline and the raw material powder obtained in the step (2) for 65 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
Example 5
Weighing 855 parts of vaseline, 42 parts of lanolin, 52 parts of honey, 7.5 parts of pseudo-ginseng powder, 0.65 part of snake gall powder, 0.45 part of artificial bezoar powder, 0.45 part of artificial musk powder, 36 parts of calamine powder, 0.16 part of amber powder, 0.42 part of pearl powder, 1.1 part of borax powder, 0.05 part of sal ammoniac powder and 17 parts of borneol;
pulverizing Notoginseng radix powder, fel Serpentis powder, artificial calculus bovis powder, artificial Moschus powder, calamina powder, succinum powder, margarita powder, borax powder, sal Ammoniacus powder, and Borneolum Syntheticum, sieving with 200 mesh sieve, and mixing to obtain mixed powder; further crushing the mixed powder to obtain raw material powder; placing honey and lanolin in an environment with the temperature controlled at 170 ℃, and sterilizing for 70 minutes; placing vaseline in an environment with the temperature controlled at 170 ℃, and sterilizing for 70 minutes; stirring until vaseline is cooled to 70 ℃; and (3) fully stirring the sterilized honey, lanolin and vaseline and the raw material powder obtained in the step (2) for 110 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
The pseudo-ginseng has the effects of dissipating blood, stopping bleeding, relieving swelling and pain, and is used for treating extravasated blood swelling and pain caused by extravasated blood internal resistance; the fel Serpentis has effects of clearing away heat and toxic materials, eliminating phlegm, relieving pain, benefiting liver, and improving eyesight; the musk has the effects of inducing resuscitation, refreshing mind, promoting blood circulation and relieving swelling, and is used for promoting qi of blood system, making fragrance flow, penetrating viscera, externally walking skin, passing twelve meridians and guiding medicine to directly reach the focus; the calamine powder can improve eyesight and promote tissue regeneration; borneol can induce resuscitation, clear heat and relieve pain, and can prevent corrosion and promote granulation when being externally used; bezoar has the effects of relieving spasm, inducing resuscitation, clearing away heat and toxic materials; pearl has the functions of tranquilizing and calming endogenous wind. The raw materials are sequentially subjected to three procedures of coarse powder, fine powder and airflow crushing, and the principle is that the medicines are driven by high-speed airflow to collide at sound velocity in a crushing chamber to be crushed.
The invention adopts a micronization process with the medicine, solves the problem of difficult absorption of the mineral medicine, ensures that the medicine easily enters tissues through skin, greatly improves the absorption rate and increases the curative effect of the medicine.
The invention has simple process and low cost, has good curative effect on various skin inflammatory diseases such as heat-toxin and blood stasis acne and the like, and is suitable for industrial production.
The invention has reasonable formula, wide distribution of each medicine in the formula, rich resources, mature technical process and easy control.
Pharmacological research shows that the external ointment for treating the acne prepared by the invention has remarkable efficacies of diminishing redness and swelling of skin inflammation, has strong antibacterial and anti-inflammatory effects in vivo and in vitro, can remarkably inhibit inflammatory swelling and increase of skin capillary permeability, can remarkably improve tolerance of pain stimulation, and has good analgesic effect. The combination of pharmacokinetic research shows that the externally applied ointment for treating whelk prepared by the invention has the effects of good absorption and high bioavailability, and long-term clinical evidence shows that the externally applied ointment for treating whelk prepared by the invention has the advantages of high action speed, clear medicinal action and effects of treating both principal and secondary aspects of a disease; acute toxicity tests are carried out on the externally-used acne treating ointment prepared by the invention, and tests show that the externally-used acne treating ointment prepared by the invention has no obvious toxic or side effect.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (8)
1. The external ointment for treating the whelk is characterized by comprising the following raw materials in parts by weight: 800-900 parts of vaseline, 35-45 parts of lanolin, 45-55 parts of honey, 6-8 parts of pseudo-ginseng powder, 0.5-0.7 part of snake gall powder, 0.3-0.5 part of artificial bezoar powder, 0.3-0.5 part of artificial musk powder, 30-40 parts of calamine powder, 0.12-0.18 part of amber powder, 0.3-0.5 part of pearl powder, 0.5-1.5 parts of borax powder, 0.04-0.06 part of sal ammoniac powder and 12-18 parts of borneol.
2. The externally-applied ointment for treating whelk of claim 1 is characterized by comprising the following raw materials in parts by weight: 850 parts of vaseline, 40 parts of lanolin, 50 parts of honey, 7 parts of pseudo-ginseng powder, 0.6 part of snake gall powder, 0.4 part of artificial bezoar powder, 0.4 part of artificial musk powder, 35 parts of calamine powder, 0.15 part of amber powder, 0.4 part of pearl powder, 1 part of borax powder, 0.05 part of sal ammoniac powder and 15 parts of borneol.
3. The externally-applied ointment for treating whelk of claim 1 is characterized by comprising the following raw materials in parts by weight: 845-855 parts of vaseline, 38-42 parts of lanolin, 48-52 parts of honey, 6.5-7.5 parts of pseudo-ginseng powder, 0.55-0.65 part of snake gall powder, 0.35-0.45 part of artificial bezoar powder, 0.35-0.45 part of artificial musk powder, 34-36 parts of calamine powder, 0.14-0.16 part of amber powder, 0.38-0.42 part of pearl powder, 0.9-1.1 part of borax powder, 0.05 part of sal ammoniac powder and 14-17 parts of borneol.
4. The method for preparing the external ointment for treating whelk according to any one of claims 1 to 3, which is characterized by comprising the following steps:
step 1: according to the weight parts of the raw materials, the pseudo-ginseng powder, the snake gall powder, the artificial bezoar powder, the artificial musk powder, the calamine powder, the amber powder, the pearl powder, the borax powder, the sal ammoniac powder and the borneol are ground, sieved and uniformly mixed to obtain mixed powder;
and 2, step: further crushing the mixed powder to obtain raw material powder;
and 3, step 3: sterilizing Mel, lanolin and vaseline;
and 4, step 4: and (3) fully stirring the sterilized honey, lanolin and vaseline and the raw material powder obtained in the step (2) for 60-120 minutes until the ointment is uniform, thus obtaining the external ointment for treating the whelk.
5. The method for preparing an externally-applied ointment for treating whelk according to claim 4, wherein in the step 1, pseudo-ginseng powder, snake gall powder, artificial bezoar powder, artificial musk powder, calamine powder, amber powder, pearl powder, borax powder, sal ammoniac powder and borneol are ground and sieved by a 200-mesh sieve;
and in the step 2, further crushing the mixed powder by using a jet mill.
6. The preparation method of the external ointment for treating acne according to claim 4, characterized in that the honey sterilization method in step 3 is as follows: placing Mel in 130-180 deg.C environment, and sterilizing for 60-90 min.
7. The method for preparing the external ointment for treating whelk according to claim 4, wherein the sterilization method of lanolin in the step 3 is as follows: placing lanolin in 130-180 deg.C environment, and sterilizing for 60-90 min.
8. The method for preparing an external ointment for treating whelk according to claim 4, wherein the method for sterilizing vaseline in step 3 comprises the following steps: placing vaseline in an environment with the temperature controlled at 130-180 ℃, and sterilizing for 60-90 minutes; stirring until vaseline is cooled to 60-80 ℃.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1403097A (en) * | 2002-10-18 | 2003-03-19 | 武汉马应龙药业集团股份有限公司 | Sore ulcer treating ointment and its prepn |
| CN105769728A (en) * | 2016-03-11 | 2016-07-20 | 福建片仔癀化妆品有限公司 | Production process of Pien Tze Huang-containing cosmetics |
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- 2022-11-27 CN CN202211495580.7A patent/CN115581714A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403097A (en) * | 2002-10-18 | 2003-03-19 | 武汉马应龙药业集团股份有限公司 | Sore ulcer treating ointment and its prepn |
| CN105769728A (en) * | 2016-03-11 | 2016-07-20 | 福建片仔癀化妆品有限公司 | Production process of Pien Tze Huang-containing cosmetics |
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| Title |
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| 林湘群;李为儒;: "红蓝光联合陈氏粉刺清治疗痤疮的疗效观察", 中国美容医学, vol. 20, no. 09, pages 1422 * |
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Application publication date: 20230110 |