CN112773822A

CN112773822A - Pharmaceutical formulation for wound healing

Info

Publication number: CN112773822A
Application number: CN202110115186.5A
Authority: CN
Inventors: 谢焕良
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-01-28
Filing date: 2021-01-28
Publication date: 2021-05-11

Abstract

The invention discloses a drug formula for wound healing, which consists of gypsum, borneol and cockroach, and the components by weight are as follows: 550g of gypsum, 35-45g of borneol and 25-35g of cockroach; the preparation method of the pharmaceutical formulation for wound healing is as follows: the method comprises the following steps: preparing materials: gypsum Fibrosum, Borneolum Syntheticum, cockroach, Os Draconis preparata, radix Angelicae Dahuricae, resina Draconis, its component is according to the weight: 550g of gypsum, 35-45g of borneol, 25-35g of cockroach, 80-100g of calcined keel, 70-90g of angelica dahurica and 40-50g of dragon's blood; step two: fermentation: the gypsum is festered and fermented by animal excreta, so that the gypsum absorbs the fine toxin; step three: ultra-fine grinding: putting the gypsum after absorbing the fine toxin, borneol, cockroach, calcined dragon bone, angelica dahurica and dragon blood into a pulverizer to perform ultrafine grinding; step four: ultrafine grinding and sieving; the invention has the beneficial effects that: the scar is better repaired, the wound is quickly healed, the pain is avoided, no side effect is caused, and other medicines are not rejected; the addition of calcined dragon bone, angelica dahurica and dragon's blood can make the curative effect obvious and further raise the efficiency of quick healing of wound.

Description

Pharmaceutical formulation for wound healing

Technical Field

The invention belongs to the technical field of medicine formulas, and particularly relates to a medicine formula for wound healing.

Background

In recent years, with the increasing incidence of disease, surgical patients have been increasing.

Wound healing refers to the healing process after the body is subjected to external force and the skin and other tissues are separated or damaged, and comprises the complex combination of regeneration of various tissues, granulation tissue proliferation and scar tissue formation, and the synergistic effect of various processes is shown. Wound healing can be divided into three types, i.e., first-stage healing, second-stage healing and third-stage healing, according to the degree of injury and whether infection exists.

In order to better repair scars, enable wounds to heal quickly and avoid rejection of other medicines caused by side effects, a medicine formula for healing the wounds is provided.

Disclosure of Invention

The invention aims to provide a medicine formula for wound healing, which can better repair scars, enable wounds to heal quickly and avoid rejection of other medicines caused by side effects.

In order to achieve the purpose, the invention provides the following technical scheme: a drug formula for wound healing comprises gypsum, borneol and cockroach, and the components by weight are as follows: 550g of gypsum, 35-45g of borneol and 25-35g of cockroach.

As a preferred technical scheme of the invention, the mortar also comprises 80-100g of calcined keel.

As a preferable technical scheme of the invention, the traditional Chinese medicine also comprises 70-90g of dahurian angelica root.

As a preferable technical proposal of the invention, the medicine also comprises 40 to 50g of dragon's blood.

A preparation method of a medicinal formula for wound healing comprises the following steps:

the method comprises the following steps: preparing materials: gypsum Fibrosum, Borneolum Syntheticum, cockroach, Os Draconis preparata, radix Angelicae Dahuricae, resina Draconis, its component is according to the weight: 550g of gypsum, 35-45g of borneol, 25-35g of cockroach, 80-100g of calcined keel, 70-90g of angelica dahurica and 40-50g of dragon's blood;

step two: fermentation: the gypsum is festered and fermented by animal excreta, so that the gypsum absorbs the fine toxin;

step three: ultra-fine grinding: putting the gypsum after absorbing the fine toxin, borneol, cockroach, calcined dragon bone, angelica dahurica and dragon blood into a pulverizer to perform ultrafine grinding;

step four: pulverizing into superfine powder, and sieving.

In a preferable technical scheme of the invention, in the second step, the time for the gypsum to be subjected to festering fermentation by the animal excrement is more than or equal to 3 years.

In the fourth step, the ultrafine powder is sieved by a standard sieve with 200 meshes.

A method for using the medicine for wound healing comprises the following steps:

the method comprises the following steps: cleaning the wound;

step two: the product is evenly smeared on the cleaned wound.

Compared with the prior art, the invention has the beneficial effects that:

(1) the scar is better repaired, the wound is quickly healed, the pain is avoided, no side effect is caused, and other medicines are not rejected;

(2) the addition of calcined dragon bone, angelica dahurica and dragon's blood can make the curative effect obvious and further raise the efficiency of quick healing of wound.

Drawings

FIG. 1 is a flow chart of a preparation method of the present invention;

FIG. 2 is a flow chart of a method of use of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

Referring to fig. 1 and fig. 2, the present invention provides a technical solution: a drug formula for wound healing comprises gypsum, borneol and cockroach, and the components by weight are as follows: 450g of gypsum, 35g of borneol and 25g of cockroach.

In this embodiment, it is preferable that 80g of forged keel is further included.

In this embodiment, preferably, 70g of radix angelicae dahuricae is further included.

In this embodiment, preferably, 40g of dragon's blood is further included.

the method comprises the following steps: preparing materials: gypsum Fibrosum, Borneolum Syntheticum, cockroach, Os Draconis preparata, radix Angelicae Dahuricae, resina Draconis, its component is according to the weight: 450g of gypsum, 35g of borneol, 25g of cockroach, 80g of calcined keel, 70g of angelica dahurica and 40g of dragon's blood;

step two: fermentation: the gypsum is festered and fermented for more than or equal to 3 years by animal excrement, so that the gypsum absorbs the fine toxicity;

step four: and (5) performing ultrafine grinding and then sieving by a standard sieve of 200 meshes.

the method comprises the following steps: cleaning the wound;

step two: the product is evenly smeared on the cleaned wound.

Gypsum is a mineral substance, has strong and cold nature, mainly enters lung channels and stomach channels according to the theory of meridians and collaterals, is used for skin diseases such as eczema and the like, has the effect of astringing dampness, is divided into gypsum and calcined gypsum, has the effects of clearing heat and purging fire, relieving restlessness and quenching thirst, and is calcined gypsum, namely calcined gypsum, has the effects of healing sore and promoting granulation, astringing dampness and stopping bleeding.

Borneol, other names: borneol, natural borneol, plum slice and plum slice, and the main components are as follows: the product is crystal obtained from resin and volatile oil of Borneolum, which is almost pure dextroborneol, and contains various terpenoids, except Borneolum, also contains sesquiterpene such as humulene, beta-elemene, caryophyllene, etc., oleanolic acid, hordenic acid, asiatic acid, Borneolum diol, cocadiol, etc.; the borneol has the following effects and effects:

the experiment shows that: the borneol has similar effect to the coronary storax pill on the anesthesia dog with acute myocardial infarction, can increase the blood flow of coronary sinus, slow down the heart rate and reduce the oxygen consumption of myocardium, and shows that: the borneol is beneficial to preventing and treating coronary spasm and can relieve myocardial damage caused by ischemia;

the borneol has a bidirectional regulation effect on central nervous excitability, and has the functions of tranquilizing and allaying excitement and restoring consciousness; the borneol has a protective effect on the brain, is beneficial to the recovery of encephaledema, protects the subsequent injury caused by cerebral ischemia and improves the damaged and awakening capability; borneol is an effective transdermal enhancer, and can promote the transdermal absorption of external corticoids, diclofenac sodium and other medicaments; the borneol can promote the medicine to penetrate through the cornea of the eye and improve the bioavailability of the medicine for the eye; the medicine is promoted to permeate through nasal mucosa, the speed of the medicine absorbed into the brain through nasal cavities is improved, the absorption amount of the medicine in brain tissues is increased, and the medicine is a quick-acting way for treating ischemic cerebrovascular insufficiency in the acute stage; the natural borneol can obviously inhibit the increase of the permeability of capillary vessels in the abdominal cavity of a mouse caused by acetic acid and has an anti-inflammatory effect; can obviously prolong the pain response time and the pain response of the mouse caused by thermal stimulation, and has the function of analgesia; the in vitro direct antiviral test shows that the compound has the function of inhibiting influenza virus; experiments show that: borneol can cause abortion of middle and late pregnant mice, and the pregnancy termination rates are respectively 100% and 91%; the borneol has anti-inflammatory and antibacterial effects, can reduce the infection of bacteria to the skin wound on the bowel and the face, and can promote the healing of the wound; borneol can increase granulation tissue structure and epidermal cell regeneration, repair skin accessory organs and has stronger wound healing effect.

The cockroach has the effects of detoxifying, dissipating blood stasis and resolving food stagnation, is mainly used for treating goiter, tumor, scrofula, abdominal mass, infantile food stagnation, sphagitis, tonsillitis, furuncle, pyogenic infection, mosquito bite and the like, is prepared into a Chinese patent medicine for application after being prepared and externally used or combined with other herbal medicines, and the Chinese patent medicine has the effects of resisting cancer, enhancing the immune function, activating non-specific immune cells, improving the immune function of a human body and strengthening the body after being prepared and used for treating cancer.

The calcined keel is a good medicinal material for relieving convulsion and calming mind, and parents can use the calcined keel to help children calm mind and calm mind if children are frightened by accident; the calcined keel is mainly calcium carbonate and calcium phosphate, contains iron, potassium, sodium, chlorine and sulfate radicals, is most viscous and astringent, has the strength of fluttering and collecting, and can astringe vigor, calm mind and play a certain role in insomnia; the calcined keel can treat the phenomenon that the ulcer is not closed for a long time, so that the wound is closed in the shortest time, and the effect is quick; the calcined keel can also treat severe palpitation amnesia, can help memory to be best preserved and restored, and solves various troubles caused by amnesia in life;

radix Angelicae Dahuricae is pungent and warm in property and is effective in dispelling pathogenic wind, relieving exterior syndrome and dispelling cold, and relieving pain, so it is commonly used for treating wind cold, headache and body pain, nasal obstruction and watery nasal discharge; radix Angelicae Dahuricae, radix Angelicae sinensis, radix Angelicae Dahuricae, radix; the angelica dahurica can expel wind, dispel cold and dry dampness, can promote lung qi, invigorate yang, improve eyesight, clear qi, dredge nasal orifices and relieve pain, so the angelica dahurica can be used for treating symptoms of stuffy nose, running nose and forehead pain in allergic rhinitis, nasosinusitis and other nasal diseases; radix Angelicae Dahuricae is pungent, warm, fragrant and dry, and good at eliminating dampness of yangming channel, eliminating dampness and stopping leukorrhagia, and can be used for treating leukorrhagia due to cold-dampness and leukorrhagia by combining with yang-warming, cold-dispelling, spleen-invigorating and dampness-removing medicines; it can be used with heat-clearing, dampness-eliminating and dampness-removing herbs to treat damp-heat invasion of lower energizer and yellow and red leucorrhea; the angelica dahurica can dispel wind and dry dampness, and the traditional Chinese medicine considers that skin pruritus is mainly caused by wind evil and dampness evil, so the angelica dahurica can be used for treating skin rheumatism pruritus symptoms; the angelica dahurica mainly contains coumarin components: imperatorin, isoimperatorin, alloimperatorin, oxypeucedanin and hydrated oxypeucedanin, and volatile oil component; radix Angelicae Dahuricae can resist central nervous system effect caused by snake venom; the decoction of radix Angelicae Dahuricae has certain inhibiting effect on Escherichia coli, Bacillus dysenteriae, Bacillus typhi, Pseudomonas aeruginosa, and Bacillus proteus; has antipyretic, antiinflammatory, analgesic, spasmolytic, and anticancer effects.

The dragon's blood has pungent and mild natured flavor, enters liver and heart meridians, has the effects of removing blood stasis and relieving pain, stopping bleeding and healing sore, is commonly used for traumatic injury or fracture and pain caused by blood stasis and stagnation, is often used together with frankincense and myrrh to enhance the effects of removing blood stasis and relieving pain, is also used for traumatic bleeding for fracture, can be used singly or together with cattail pollen for grinding and spreading on an affected part, and has the effects of healing sore for a long time and promoting tissue regeneration together with frankincense and myrrh.

The product is mainly used for treating poor wound healing and difficult wound healing after operation; when the product is used for scald, the scald ointment is needed to remove fire toxin and then the wound is closed by the traditional Chinese medicine.

Example 2

Referring to fig. 1 and fig. 2, the present invention provides a technical solution: a drug formula for wound healing comprises gypsum, borneol and cockroach, and the components by weight are as follows: 500g of gypsum, 40g of borneol and 30g of cockroach.

In this embodiment, it is preferable that the steel further includes 90g of forged keel.

In this embodiment, preferably, 80g of radix angelicae dahuricae is further included.

In this embodiment, preferably, 45g of dragon's blood is further included.

the method comprises the following steps: preparing materials: gypsum Fibrosum, Borneolum Syntheticum, cockroach, Os Draconis preparata, radix Angelicae Dahuricae, resina Draconis, its component is according to the weight: 500g of gypsum, 40g of borneol, 30g of cockroach, 90g of calcined keel, 80g of angelica dahurica and 45g of dragon's blood;

the method comprises the following steps: cleaning the wound;

step two: the product is evenly smeared on the cleaned wound.

Example 3

Referring to fig. 1 and fig. 2, the present invention provides a technical solution: a drug formula for wound healing comprises gypsum, borneol and cockroach, and the components by weight are as follows: 550g of gypsum, 45g of borneol and 35g of cockroach.

In this embodiment, preferably, the steel plate further comprises 100g of forged keel.

In this embodiment, preferably, 90g of radix angelicae dahuricae is further included.

In this embodiment, preferably, 50g of dragon's blood is further included.

the method comprises the following steps: preparing materials: gypsum Fibrosum, Borneolum Syntheticum, cockroach, Os Draconis preparata, radix Angelicae Dahuricae, resina Draconis, its component is according to the weight: 550g of gypsum, 45g of borneol, 35g of cockroach, 100g of calcined keel, 70-90g of angelica dahurica and 40-50g of dragon's blood;

In the second step, the time of the gypsum festering and fermenting through the animal excrement is more than or equal to 3 years.

In the fourth step, the mixture is sieved by a standard sieve of 200 meshes after being subjected to ultrafine grinding.

the method comprises the following steps: cleaning the wound;

step two: the product is evenly smeared on the cleaned wound.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A pharmaceutical formulation for wound healing, characterized by: the composition comprises gypsum, borneol and cockroach, and comprises the following components in parts by weight: 550g of gypsum, 35-45g of borneol and 25-35g of cockroach.

2. A pharmaceutical formulation for use in wound healing according to claim 1, wherein: also comprises 80-100g of calcined keel.

3. A pharmaceutical formulation for use in wound healing according to claim 1, wherein: 70-90g of radix angelicae dahuricae is also included.

4. A pharmaceutical formulation for use in wound healing according to claim 1, wherein: also comprises 40-50g of sanguis Draxonis.

5. A pharmaceutical formulation for use in wound healing according to any one of claims 1 to 4, wherein: the preparation method of the pharmaceutical formulation for wound healing is as follows:

step four: pulverizing into superfine powder, and sieving.

6. A pharmaceutical formulation for use in wound healing according to claim 5, wherein: in the second step, the time of the gypsum festering and fermenting through the animal excrement is more than or equal to 3 years.

7. A pharmaceutical formulation for use in wound healing according to claim 5, wherein: in the fourth step, the superfine powder is sieved by a standard sieve of 200 meshes.

8. A pharmaceutical formulation for use in wound healing according to any one of claims 1 to 7, wherein: the method of use of the drug for wound healing is as follows:

the method comprises the following steps: cleaning the wound;

step two: the product is evenly smeared on the cleaned wound.