CN115517266A - Chlorine dioxide effervescent pellet - Google Patents
Chlorine dioxide effervescent pellet Download PDFInfo
- Publication number
- CN115517266A CN115517266A CN202211387943.5A CN202211387943A CN115517266A CN 115517266 A CN115517266 A CN 115517266A CN 202211387943 A CN202211387943 A CN 202211387943A CN 115517266 A CN115517266 A CN 115517266A
- Authority
- CN
- China
- Prior art keywords
- chlorine dioxide
- mixture
- component
- effervescent
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 title claims abstract description 148
- 239000004155 Chlorine dioxide Substances 0.000 title claims abstract description 74
- 235000019398 chlorine dioxide Nutrition 0.000 title claims abstract description 74
- 239000008188 pellet Substances 0.000 title claims abstract description 22
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 48
- 239000000853 adhesive Substances 0.000 claims abstract description 36
- 230000001070 adhesive effect Effects 0.000 claims abstract description 36
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 31
- 239000008187 granular material Substances 0.000 claims abstract description 18
- 229910001919 chlorite Inorganic materials 0.000 claims abstract description 16
- 229910052619 chlorite group Inorganic materials 0.000 claims abstract description 16
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000002535 acidifier Substances 0.000 claims abstract description 12
- 239000004094 surface-active agent Substances 0.000 claims abstract description 12
- 230000003213 activating effect Effects 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims description 91
- 239000011257 shell material Substances 0.000 claims description 45
- 238000002156 mixing Methods 0.000 claims description 41
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 16
- 238000005520 cutting process Methods 0.000 claims description 15
- 238000004898 kneading Methods 0.000 claims description 14
- 238000010438 heat treatment Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 238000005303 weighing Methods 0.000 claims description 10
- 239000000645 desinfectant Substances 0.000 claims description 9
- 238000001125 extrusion Methods 0.000 claims description 9
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 8
- ROOXNKNUYICQNP-UHFFFAOYSA-N ammonium persulfate Chemical compound [NH4+].[NH4+].[O-]S(=O)(=O)OOS([O-])(=O)=O ROOXNKNUYICQNP-UHFFFAOYSA-N 0.000 claims description 8
- 238000005485 electric heating Methods 0.000 claims description 8
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 6
- 239000008118 PEG 6000 Substances 0.000 claims description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 6
- 229920001030 Polyethylene Glycol 4000 Polymers 0.000 claims description 6
- 229920002584 Polyethylene Glycol 6000 Polymers 0.000 claims description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
- -1 acetylene glycols Chemical class 0.000 claims description 6
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 6
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 5
- 239000001110 calcium chloride Substances 0.000 claims description 5
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 5
- 238000007906 compression Methods 0.000 claims description 5
- 230000006835 compression Effects 0.000 claims description 5
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 5
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 4
- 229910001870 ammonium persulfate Inorganic materials 0.000 claims description 4
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 4
- QXIKMJLSPJFYOI-UHFFFAOYSA-L calcium;dichlorite Chemical compound [Ca+2].[O-]Cl=O.[O-]Cl=O QXIKMJLSPJFYOI-UHFFFAOYSA-L 0.000 claims description 4
- 235000015165 citric acid Nutrition 0.000 claims description 4
- 239000001341 hydroxy propyl starch Substances 0.000 claims description 4
- 235000013828 hydroxypropyl starch Nutrition 0.000 claims description 4
- 235000006408 oxalic acid Nutrition 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical compound [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 claims description 4
- 229960002218 sodium chlorite Drugs 0.000 claims description 4
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims description 3
- LCPVQAHEFVXVKT-UHFFFAOYSA-N 2-(2,4-difluorophenoxy)pyridin-3-amine Chemical compound NC1=CC=CN=C1OC1=CC=C(F)C=C1F LCPVQAHEFVXVKT-UHFFFAOYSA-N 0.000 claims description 3
- 244000247812 Amorphophallus rivieri Species 0.000 claims description 3
- 235000001206 Amorphophallus rivieri Nutrition 0.000 claims description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 3
- 229920001661 Chitosan Polymers 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 3
- 229920002581 Glucomannan Polymers 0.000 claims description 3
- 229920002907 Guar gum Polymers 0.000 claims description 3
- 229920002752 Konjac Polymers 0.000 claims description 3
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims description 3
- 239000004373 Pullulan Substances 0.000 claims description 3
- 229920001218 Pullulan Polymers 0.000 claims description 3
- 229920002125 Sokalan® Polymers 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
- WOHVONCNVLIHKY-UHFFFAOYSA-L [Ba+2].[O-]Cl=O.[O-]Cl=O Chemical compound [Ba+2].[O-]Cl=O.[O-]Cl=O WOHVONCNVLIHKY-UHFFFAOYSA-L 0.000 claims description 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 claims description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 3
- 239000011230 binding agent Substances 0.000 claims description 3
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 3
- 235000010216 calcium carbonate Nutrition 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 3
- 229920002678 cellulose Polymers 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- 235000010980 cellulose Nutrition 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 239000008273 gelatin Substances 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 229940046240 glucomannan Drugs 0.000 claims description 3
- 238000005469 granulation Methods 0.000 claims description 3
- 230000003179 granulation Effects 0.000 claims description 3
- 239000000665 guar gum Substances 0.000 claims description 3
- 235000010417 guar gum Nutrition 0.000 claims description 3
- 229960002154 guar gum Drugs 0.000 claims description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 3
- 239000000252 konjac Substances 0.000 claims description 3
- 235000010485 konjac Nutrition 0.000 claims description 3
- 229940116298 l- malic acid Drugs 0.000 claims description 3
- 229910052744 lithium Inorganic materials 0.000 claims description 3
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 3
- 239000001095 magnesium carbonate Substances 0.000 claims description 3
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 3
- 235000014380 magnesium carbonate Nutrition 0.000 claims description 3
- 235000011090 malic acid Nutrition 0.000 claims description 3
- 229920000609 methyl cellulose Polymers 0.000 claims description 3
- 239000001923 methylcellulose Substances 0.000 claims description 3
- 235000010981 methylcellulose Nutrition 0.000 claims description 3
- 239000001814 pectin Substances 0.000 claims description 3
- 235000010987 pectin Nutrition 0.000 claims description 3
- 229920001277 pectin Polymers 0.000 claims description 3
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 claims description 3
- 125000000914 phenoxymethylpenicillanyl group Chemical group CC1(S[C@H]2N([C@H]1C(=O)*)C([C@H]2NC(COC2=CC=CC=C2)=O)=O)C 0.000 claims description 3
- 235000011007 phosphoric acid Nutrition 0.000 claims description 3
- 239000004584 polyacrylic acid Substances 0.000 claims description 3
- 239000011736 potassium bicarbonate Substances 0.000 claims description 3
- 229910000028 potassium bicarbonate Inorganic materials 0.000 claims description 3
- 235000015497 potassium bicarbonate Nutrition 0.000 claims description 3
- 229910000027 potassium carbonate Inorganic materials 0.000 claims description 3
- 235000011181 potassium carbonates Nutrition 0.000 claims description 3
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 claims description 3
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 claims description 3
- VISKNDGJUCDNMS-UHFFFAOYSA-M potassium;chlorite Chemical compound [K+].[O-]Cl=O VISKNDGJUCDNMS-UHFFFAOYSA-M 0.000 claims description 3
- 235000019423 pullulan Nutrition 0.000 claims description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 3
- 235000017550 sodium carbonate Nutrition 0.000 claims description 3
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 claims description 3
- CHQMHPLRPQMAMX-UHFFFAOYSA-L sodium persulfate Substances [Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O CHQMHPLRPQMAMX-UHFFFAOYSA-L 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000011975 tartaric acid Substances 0.000 claims description 3
- 235000002906 tartaric acid Nutrition 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 238000007599 discharging Methods 0.000 claims description 2
- 230000000087 stabilizing effect Effects 0.000 claims description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 abstract description 8
- 238000006243 chemical reaction Methods 0.000 abstract description 6
- 239000007938 effervescent tablet Substances 0.000 description 19
- 239000002245 particle Substances 0.000 description 16
- 238000012216 screening Methods 0.000 description 14
- 238000007873 sieving Methods 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 10
- 239000002994 raw material Substances 0.000 description 10
- 239000002893 slag Substances 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 238000001035 drying Methods 0.000 description 6
- 239000011148 porous material Substances 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 238000005429 filling process Methods 0.000 description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 238000011049 filling Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 238000000265 homogenisation Methods 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 238000007493 shaping process Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000004913 activation Effects 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 238000009924 canning Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 206010012504 Dermatophytosis Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241001460074 Microsporum distortum Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 229920001688 coating polymer Polymers 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 239000002274 desiccant Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 235000012438 extruded product Nutrition 0.000 description 1
- 239000011361 granulated particle Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
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- 230000003993 interaction Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
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- 231100000331 toxic Toxicity 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
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- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the technical field of chlorine dioxide disinfection, in particular to a chlorine dioxide effervescent pellet which comprises a chlorine dioxide disinfection tablet, wherein the outside of the chlorine dioxide disinfection tablet is wrapped by an outer shell, and the chlorine dioxide disinfection tablet comprises a component A and a component B; the component A comprises: 20-50 parts of chlorite, 0.5-5 parts of effervescent agent, 0.2-1 part of surfactant and A component adhesive; the component B comprises: 3-15 parts of an acidifying agent, 0.5-5 parts of an activating agent and 10-40 parts of a B-component adhesive, wherein the weight ratio of the A-component adhesive to the B-component adhesive is above. The product chlorine dioxide disinfection granule is divided into two components, the direct reaction between the two components is avoided, and the outer shell is wrapped outside the chlorine dioxide disinfection granule, so that the moisture absorption resistance of the product is effectively improved, the problem of product adhesion is effectively solved, and the product can be effectively stored for a long time when placed in chlorine dioxide disinfection equipment.
Description
Technical Field
The invention relates to the technical field of chlorine dioxide disinfection, in particular to a chlorine dioxide effervescent pellet.
Background
Chlorine dioxide has excellent bactericidal performance, has strong adsorption and penetration capacity on the cell wall of bacteria, can oxidize nucleic acid in the bacterial cell, and forcibly grabs electrons to lose the activity of the nucleic acid, thereby preventing anabolism of the bacteria, achieving the aims of disinfection, sterilization and deodorization, and having strong inactivation capacity on the bacteria, viruses and the like. Chlorine dioxide becomes the only A1 grade green sterilizing disinfectant approved by the agency certification of WHO (world health organization), FAO (food and agricultural organization of the United nations) and the like due to high efficiency and safety of the chlorine dioxide, and is widely applied to the sterilizing, sterilizing and deodorizing processes in the fields of food industry, medical treatment, pharmacy, livestock raising, aquaculture, food, drinking water and public environment. Under the ultralow concentration within the limit value, chlorine dioxide is safe to human bodies, and the dynamic space disinfection of the ultralow-concentration chlorine dioxide shows huge potential application requirements, so that the comprehensive disinfection without dead angles in all directions in a space range is realized. Chlorine dioxide effervescent tablet (CIO 2). The use does not need activation, the process of dissolving and releasing the chlorine dioxide of the product is not limited by water quantity, quantitative chlorine dioxide can be generated only by putting the tablet into water, the complicated activation operation can be thoroughly avoided, and meanwhile, the active ingredients are completely dissolved into the water. Safe transportation and storage, no toxic and side residue after use, and is an ideal disinfection solution for space low-concentration chlorine dioxide gas.
The chlorine dioxide effervescent tablet is applied to realize the safe disinfection atmosphere environment which is relatively fixed in disinfection time, action range and use dosage and coexists with people, and is the core technology of the disinfection machine which realizes human-machine coexistence and real-time no dead angle.
The man-machine interaction disinfection device can refer to the following patent documents applied by the applicant: a fresh air duct type air disinfection device disclosed in publication No. CN215723897U, a supplementary material air disinfection device disclosed in publication No. CN216448341U, and a supplementary material air disinfection device disclosed in publication No. CN216448341U
In the application process, in the environment with excessive humidity, wherein the environment comprises the air humidity around the equipment and the water vapor in the water tank in the machine equipment, the chlorine dioxide effervescent tablet can generate the problems of moisture absorption, adhesion and the like when absorbing the water vapor in the environment, and the use effect is seriously influenced. If the disinfection effect or the human-computer coexistence safety is affected by depending on manual feeding once or several times every day, such as missing feeding, wrong feeding, multiple feeding and the like of operators, a full-automatic program control feeding method is needed to ensure the maintenance of the timing, the fixed dose and the fixed concentration of the chlorine dioxide in a certain space atmosphere. Therefore, the original chlorine dioxide effervescent tablet needs to be upgraded by breaking through the anti-adhesion technology of the human-computer coexistence disinfection effervescent pellet.
A domestic granted patent CN 2008100545718-unitary solid chlorine dioxide effervescent tablet and a preparation method thereof; CN2011101305751- "instant chlorine dioxide effervescent tablet and its preparation method"; CN 2011101408245-a solid chlorine dioxide effervescent tablet and a preparation method thereof and a published patent CN 201410257459X-a chlorine dioxide effervescent tablet for killing dermatophytosis bacteria and fungi and a preparation method thereof; CN 2017107179853-A preparation method of chlorine dioxide effervescent tablet; CN 2021104311847-A chlorine dioxide effervescent tablet, its preparation method and application, etc. are the preparation methods of chlorine dioxide effervescent tablet, but the above-mentioned techniques can not meet the requirements of resisting moisture and preventing adhesion.
Disclosure of Invention
The invention aims to solve the defects that when chlorine dioxide effervescent tablets in the prior art absorb water vapor in the environment, the problems of moisture absorption, adhesion and the like are generated, and the using effect is seriously influenced.
In order to achieve the purpose, the invention adopts the following technical scheme:
a chlorine dioxide effervescent pellet comprises a chlorine dioxide disinfection granule, wherein the outside of the chlorine dioxide disinfection granule is wrapped by an outer shell, and the chlorine dioxide disinfection granule comprises a component A and a component B; the component A comprises: 20-50 parts of chlorite, 0.5-5 parts of effervescent agent, 0.2-1 part of surfactant and A component adhesive; the component B comprises: 3-15 parts of acidifying agent, 0.5-5 parts of activating agent and 10-40 parts of component B adhesive, wherein the weight ratio of the component A adhesive to the component B adhesive is above.
The chlorite is one or a mixture of more of sodium chlorite, potassium chlorite, calcium chlorite and barium chlorite.
The acidulant is one or a mixture of oxalic acid, succinic acid, citric acid, L-malic acid, phosphoric acid and tartaric acid.
The activating agent is one or a mixture of more of ammonium persulfate, lithium persulfate, potassium persulfate and sodium persulfate.
The effervescent agent is one or more of sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate and magnesium carbonate
The surfactant is one or a mixture of more of basic acetylene glycol, ethoxylated acetylene glycol, sodium dodecyl sulfate and sodium dodecyl benzene sulfonate
The component A adhesive is one or a mixture of more of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000 and PVA 1788; the B component adhesive is one or a mixture of more of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000, PVA1788, polyacrylic acid, pectin, water-soluble starch and guar gum.
The forming of the chlorine dioxide disinfection tablet comprises the following steps: weighing chlorite, effervescent agent, surfactant and A component adhesive in proportion and mixing to obtain a mixture A;
then, weighing the acidifying agent, the activating agent and the component B adhesive in proportion and mixing to obtain a mixture B;
and (3) mixing the mixture A, mixing the mixture B, and respectively adding the mixed mixture A and the mixed mixture B into a double-pipe feeding screw extruder for extrusion and granulation.
Adding calcium chloride micro powder into the mixture A and/or the mixture B and then extruding;
when the mixture A is mixed: the mixing temperature is 40-70 ℃, the feeding amount is 1-20Kg each time, the heating mode is electrical heating, the paddle is sigma type, the rotating speed N1 of the paddle is 15-25 revolutions per minute, the rotating speed N2 is 35-55 revolutions, and the materials are kneaded, discharged, cooled and crushed;
when the mixture B is mixed: the mixing temperature is 60-90 ℃, the feeding amount is 1-10Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 20-25 revolutions per minute, the rotating speed N2 is 40-50 revolutions, and the kneading, discharging, cooling and crushing are carried out;
the double-tube feeding screw extruder has the feeding section of room temperature, the compression section of 35-55 deg.c, the homogenizing section of 50-70 deg.c, the head and mouth mold section of 55-65 deg.c, water content in the material controlled to less than or equal to 0.025%, screw rotation speed of 10-20 (r/min), flow stabilizing and setting section of 60-120mm length, drawing ratio of 0.95-1.2, extruding mouth mold inside diameter of 0.5-2mm and cutting length of 0.5-2mm.
The outer shell material is one or a mixture of more of methylcellulose, carboxymethylcellulose, pullulan polysaccharide cellulose, hydroxypropyl methylcellulose, chitosan, konjac glucomannan, gelatin and hydroxypropyl starch;
outer shell includes public shell and female shell, public shell open end has the portion of inserting, female shell open end has the cover portion of establishing that supplies the portion of inserting to insert.
The chlorine dioxide effervescent pellet provided by the invention has the beneficial effects that: this product chlorine dioxide disinfection grain divide into two kinds of components, avoids direct emergence reaction each other to at the outer shell of chlorine dioxide disinfection grain outside parcel, effectively improve the anti moisture absorption ability of product, effectively solve the sticky problem of product, guarantee that this product can effectively be preserved for a long time in chlorine dioxide disinfection equipment.
Drawings
FIG. 1 is a process flow diagram of the present invention;
FIG. 2 is a schematic view of the construction of a double-tube feed screw extruder of the present invention;
FIG. 3 is an exploded view of a first embodiment of the effervescent pellet of the present invention;
FIG. 4 is a schematic combined structure of a first embodiment of the effervescent tablet of the present invention;
FIG. 5 is an exploded view of a second embodiment of the effervescent pellet of the present invention;
fig. 6 is a structural schematic diagram of a second embodiment of the effervescent bomb combined according to the invention.
In the figure: 1. a feed inlet of a mixture A, a feed inlet of a mixture B, a shell of a double-material extruder 3 and a screw of the double-material extruder 4.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
The first embodiment is as follows:
a chlorine dioxide effervescent pellet comprises a chlorine dioxide disinfection granule, wherein the outside of the chlorine dioxide disinfection granule is wrapped by an outer shell, and the chlorine dioxide disinfection granule comprises a component A and a component B; the component A comprises: 20-50 parts of chlorite, 0.5-5 parts of effervescent agent, 0.2-1 part of surfactant and A component adhesive; the component B comprises: 3-15 parts of an acidifying agent, 0.5-5 parts of an activating agent and 10-40 parts of a B-component adhesive, wherein the weight ratio of the A-component adhesive to the B-component adhesive is above.
This product chlorine dioxide disinfection grain divide into two kinds of components, avoids directly reacting each other to outer shell of outside parcel at chlorine dioxide disinfection grain effectively improves the anti moisture absorption ability of product, effectively solves the sticky problem of product, guarantees that this product is placed and can effectively preserve for a long time in chlorine dioxide disinfecting equipment.
Example two:
referring to fig. 1-6, a process for preparing a chlorine dioxide effervescent pellet comprises the following steps:
premixing ingredients: weighing chlorite, an effervescent agent, a surfactant and the component A adhesive to mix into a mixture A; weighing an acidifying agent, an activating agent and a B-component adhesive to mix into a mixture B; the two mixtures are respectively mixed on the premise of the raw materials, the effervescence reaction activity of the chlorine dioxide can be guaranteed without adding a drying agent and a release agent, the chlorite and the acidifier are respectively placed in the mixture A and the mixture B, the reaction rate of the chlorite and the acidifier can be respectively slowed down by adopting a separate mixing mode, and if the chlorite and the acidifier are directly mixed together for mixing, a great amount of reaction loss can be caused in the heating mixing process; this problem is not present after separate mixing, which in turn forms a complex with the binder, which greatly slows down the reaction rate (which may be by 5-10 orders of magnitude less), and only after the binder is dissolved away by the water during final use will the acidulant and chlorite be allowed to re-react at a high rate.
Drying materials: respectively drying the mixture A and the mixture B to reduce the water content in the raw materials;
mixing and kneading: adding the mixture A into a mixing kneader, mixing and kneading uniformly, and crushing after cooling a kneaded material; the mixture B is mixed and kneaded evenly in a mixing and kneading machine, and the mixture B is crushed after being kneaded, discharged and cooled; when the mixture a was kneaded: the mixing temperature is 40-70 ℃, the feeding amount is 1-20Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 15-25 revolutions per minute, and the rotating speed N2 of the paddle is 35-55 revolutions per minute; when the mixture B was kneaded: the mixing temperature is 60-90 ℃, the feeding amount is 1-10Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 20-25 revolutions per minute, and the rotating speed N2 of the paddle is 40-50 revolutions per minute;
the mixture A and the mixture B are mixed respectively, on one hand, modification of a polymer is realized, on the other hand, mixing is performed, the shelf life of a product can be prolonged, if raw materials are not mixed, the formed disinfectant particles can absorb moisture of an effervescent shell, so that even if the disinfectant particles are wrapped by a layer of effervescent shell, a serious moisture absorption problem can still be generated, and the problem of moisture absorption of the product can not be effectively solved.
Extruding and granulating: adding a forming agent into the mixture A or the mixture B, wherein the forming agent can assist the mixture A and the mixture B to be extruded together into a more regular shape, so that the metering and the loading of an outer shell of an effervescent bomb are facilitated, the mixture A and the mixture B are directly extruded and are not easy to form a regular shape when the forming agent is not used, the mixture A and the mixture B can be better kneaded and formed by adding the forming agent, the integrity and the compactness of an extruded product can be ensured by better kneading together, the moisture resistance effect can be improved, then the mixture A and the mixture B are respectively added into a double-tube feeding screw extruder, and the mixture A and the mixture B are extruded by the double-tube feeding screw extruder and then granulated; when the double-tube feeding screw extruder works: the temperature of the feeding section is room temperature, the temperature of the compression section is 35-55 ℃, the temperature of the homogenization section is 50-70 ℃, the temperature of the nose and mouth mold sections is 55-65 ℃, the water content in the raw materials is controlled to be less than or equal to 0.025%, the rotating speed of the screw is 10-20 (r/min), the length of the steady flow shaping section is 60-120mm, the traction ratio is 0.95-1.2, the inner diameter of the extrusion mouth mold is 0.5-2mm, and the cutting length is 0.5-2mm. Adopting a low-temperature double-tube feeding screw extrusion granulation process technology, preparing the mixture A subjected to bonding molding and the mixture B subjected to bonding molding and a forming agent into effervescent granule solids with specified shapes and sizes by a double-tube feeding screw extrusion technology, mixing, compressing and forming the mixture A and the mixture B after mixing by a double-tube feeding screw extruder, and then pelletizing to ensure the disinfection effect of disinfectant granules;
screening: screening the granulated particles to obtain disinfectant particles with proper size; the screening technology is secondary screening, and because the effervescent granules to be filled into the bomb are crisp, irregular broken slag is difficult to avoid during cutting, and accidental adhesive large granules can be generated due to uncooled phenomenon after cutting. If the shell is directly packed, the former can lead to the crisp shell and the seriously shortened shelf life. The latter can lead to jamming during casing, to crushing of the casing or to damage to the equipment, and must be screened
As an embodiment of the screening, the screening includes: first-stage sieving: setting the diameter of a sieve pore to be 0.2-0.4mm, sieving out the crushed slag with the diameter lower than the diameter, feeding the crushed slag into any material cylinder of the double-pipe feeding screw extruder for re-extrusion molding and cutting, and feeding the sieved particles into a secondary sieving;
and (4) secondary sieving: setting the diameter of a sieve pore to be 2mm, enabling the sieved particles to enter a shell filling process, returning the large particles left after sieving to any material cylinder of the double-tube feeding screw extruder, and extruding, molding and cutting again;
the screening is carried out by adopting vibration screening, the diameter of a screen hole arranged at the first stage is 0.2-0.4mm, the slag which is lower than the diameter is screened out, and the slag returns to the charging barrel for reshaping, extruding and cutting; and (4) feeding the rest particles into a second stage, setting the screen holes to be 2-3mm directly, feeding the screened particles into a shell filling process, and feeding the rest large particles back into the charging barrel for reshaping, extruding and cutting.
Shell installation: the screened disinfectant granules are filled into an effervescent shell.
The manufacturing process of the chlorine dioxide effervescent pellet comprises an inner layer separation and adhesion technology, a forming technology, a screening technology and an outer layer shell technology, so that the long-term storage of the chlorine dioxide effervescent pellet product is realized, the moisture absorption resistance of the product is effectively improved, the problem of product adhesion is effectively solved, and the product can be effectively stored for a long time when placed in chlorine dioxide disinfection equipment;
through the mixing step to modify the polymer and combining the shell-coated double-layer humidity control technology, the anti-adhesion effervescent tablet can solve the problem that the chlorine dioxide disinfection effervescent tablet is easy to adhere after being stored in a low-temperature medium-humidity environment (lower than 20 ℃ and 30-70% humidity);
the anti-adhesion effervescent pellet solves the problem that the chlorine dioxide disinfection effervescent tablets are easy to adhere within hours under a high-temperature and high-humidity environment (higher than 35 ℃ and higher than 90% humidity);
the coating polymer and the chlorine dioxide disinfection effervescent bullet anti-adhesion modified polymer with anti-adhesion property under high humidity are designed to have small influence on the reduction of the activity of chlorine dioxide (actually measured to be less than 10 percent in 28 days).
The raw materials comprise the following components in percentage by weight: 20-50 parts of chlorite, 3-15 parts of acidifier, 0.5-5 parts of activator, 10-40 parts of A-component adhesive and B-component adhesive, 0.5-5 parts of effervescent agent and 0.2-1 part of surfactant.
For example, 1-30 parts of the adhesive of the A component and 1-30 parts of the adhesive of the B component.
Example three:
a preparation process of a chlorine dioxide effervescent pellet comprises the following steps:
premixing ingredients: weighing 20-50 parts of chlorite, 0.5-5 parts of effervescent agent, 0.2-1 part of surfactant and the component A adhesive in proportion to mix into a mixture A; weighing 3-15 parts of acidifying agent, 0.5-5 parts of activating agent and B-component adhesive in proportion to mix into a mixture B, wherein the A-component adhesive and the B-component adhesive account for 10-40 parts in total, and the raw materials are in parts by weight;
wherein the chlorite is one or a mixture of more of sodium chlorite, potassium chlorite, calcium chlorite and barium chlorite;
the acidulant is one or more of oxalic acid, succinic acid, citric acid, L-malic acid, phosphoric acid, and tartaric acid;
the activating agent is one or a mixture of more of ammonium persulfate, lithium persulfate, potassium persulfate and sodium persulfate;
the adhesive of the component A is one or a mixture of more of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000 and PVA 1788;
the B component adhesive is one or a mixture of more of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000, PVA1788, polyacrylic acid, pectin, water-soluble starch and guar gum;
the effervescent shell material is one or more of methylcellulose, carboxymethylcellulose, pullulan polysaccharide cellulose, hydroxypropyl methylcellulose, chitosan, konjac glucomannan, gelatin and hydroxypropyl starch;
the effervescent is one or more of sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate and magnesium carbonate;
the forming agent is calcium chloride micro powder;
the surfactant is one or more of basic acetylene glycol, ethoxylated acetylene glycol, sodium dodecyl sulfate and sodium dodecyl benzene sulfonate.
Drying materials: drying all the raw materials of the formula at 70 ℃ for 12 hours respectively to remove moisture;
mixing and kneading: adding the mixture A into a mixing kneader, mixing and kneading uniformly, wherein the mixing temperature is 40-70 ℃, the feeding amount is 1-20Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 15-25 revolutions per minute, the rotating speed N2 of the paddle is 35-55 revolutions per minute, and the mixture is kneaded, discharged, cooled and crushed; then mixing and kneading the mixture B uniformly in a mixing kneader, wherein the mixing temperature is 60-90 ℃, the feeding amount is 1-10Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 20-25 revolutions per minute, the rotating speed N2 of the paddle is 40-50 revolutions per minute, and the mixture B is kneaded, discharged, cooled and crushed;
and (3) extruding and granulating: adding calcium chloride micropowder into the mixture A or the mixture B, then respectively adding the mixture A and the mixture B into a double-tube feeding screw extruder, wherein the feeding section is room temperature, the compression section is controlled to be 35-55 ℃, the homogenization section is controlled to be 50-70 ℃, the head and mouth mold sections are controlled to be 55-65 ℃, the water content in the raw materials is controlled to be less than or equal to 0.025 percent, the screw rotation speed is 10-20 (r/min), the length of the steady flow shaping section is 60-120mm, the traction ratio is 0.95-1.2, the inner diameter of the extrusion mouth mold is 0.5-2mm, and the cutting length is 0.5-2mm;
screening: first-stage sieving: setting the diameter of the sieve pores to be 0.2-0.4mm, sieving out the crushed slag with the diameter lower than the diameter, returning the sieved crushed slag to the material cylinder for reshaping, extruding and cutting; the screened particles enter a second stage;
and (4) secondary screening: setting the diameter of a sieve pore to be 2-3mm, feeding the sieved particles into a shell filling process, and feeding the large particles left after sieving back into a charging barrel for reshaping, extruding and cutting;
shell installation: filling the disinfectant granules subjected to secondary screening into an effervescent shell, and butting the male shell and the female shell to form a complete effervescent bullet;
canning of finished disinfection effervescent tablets: and (3) filling the disinfection effervescent bomb into a finished product tank, wherein the finished product tank is provided with an oblique angle mechanism and an elastic sheet, and automatically sliding down one disinfection effervescent bomb when the elastic sheet is pushed each time to finish automatic feeding.
Example four:
a preparation process of a chlorine dioxide effervescent pellet comprises the following steps:
premixing ingredients: weighing 10 parts of sodium chlorite, 20 parts of calcium chlorite, 0.5 part of sodium bicarbonate, 0.5 part of calcium carbonate, 0.2 part of butynediol, 0.4 part of sodium dodecyl sulfate, 1788-10 parts of PVA and 4000-5 parts of PEG to form a mixture A; weighing 3 parts of oxalic acid, 3 parts of citric acid, 1 part of ammonium persulfate, 1788-2 parts of PVA and 4000-1 parts of PEG to form a mixture B, wherein the weight ratio is shown in the specification;
drying materials: drying all the raw materials of the formula at 70 ℃ for 12 hours respectively to remove moisture;
mixing and kneading: adding the mixture A into a mixing kneader, mixing and kneading uniformly, wherein the mixing temperature is 45 ℃, the feeding amount is 4.5Kg each time, the heating mode is electric heating, the paddle is sigma-shaped, the rotating speed N1 of the paddle is 20 revolutions per minute, the rotating speed N2 is 48 revolutions, and the mixture A is kneaded, discharged and cooled and then crushed; mixing and kneading the mixture B uniformly in a mixing and kneading machine, wherein the mixing temperature is 70 ℃, the feeding amount is 1Kg each time, the heating mode is electric heating, the paddle is sigma-shaped, the rotating speed N1 of the paddle is 20 revolutions per minute, the rotating speed N2 of the paddle is 40 revolutions per minute, and the mixture B is kneaded, discharged and cooled and then crushed;
and (3) extruding and granulating: respectively adding the mixture A and the mixture B after mixing and kneading and 10 parts of forming agent calcium chloride micro powder into a double-pipe feeding screw extruder, wherein the feeding section is room temperature, the compression section is controlled to 40 ℃, the homogenization section is controlled to 60 ℃, the head and mouth mold sections are controlled to 65 ℃, the moisture in the raw materials is controlled to be less than or equal to 0.025%, the rotating speed of the screw is 12 (r/min), the length of the steady flow shaping section is 80mm, the traction ratio is 1.1, the inner diameter of the extrusion mouth mold is 1mm, and the cutting length is 1mm;
referring to fig. 2, a mixture a is added into a feed port 1 of a mixture a, a mixture B is added into a feed port 2 of a mixture B, a forming agent is added into the feed port 1 of the mixture a or the feed port 2 of the mixture B, and the three materials are mixed, compressed and extruded by a screw 4 of a double-material extruder in a shell 3 of the double-material extruder, and finally, granulated.
First-stage sieving: setting the diameter of the sieve pore to be 0.2-0.4mm, sieving out the crushed slag with the diameter lower than the diameter, returning the crushed slag into the charging barrel, and reshaping, extruding and cutting the crushed slag; the screened particles enter a second stage;
and (4) secondary sieving: setting the diameter of a sieve pore to be 2mm, enabling the sieved particles to enter a shell filling process, and returning the large particles left after sieving to the charging barrel for reshaping, extruding and cutting;
shell installation: filling the disinfectant granules subjected to secondary screening into an effervescent shell, wherein the shell is made of hydroxypropyl starch male and female shells which are butted to form a complete effervescent pellet;
referring to fig. 3-6, the effervescent shell is designed as a male shell and a female shell, the male shell half is provided with a protrusion, the female shell half is provided with a groove, and the effervescent tablet particles after molding and screening can be loaded to form a pill-shaped effervescent pellet or an elliptical capsule-shaped effervescent pellet.
Canning of finished disinfection effervescent tablets: pack the disinfection effervescent bomb into the finished product jar, the finished product jar sets up bevel mechanism and elastic sheet, and elastic sheet can regularly start under intelligent control system, and the automatic several disinfection effervescent bombs that slide down when pushing up the elastic sheet every time accomplish automatic feeding.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any technical solutions, concepts and designs obtained by equivalent substitutions or changes of the technical solutions and the inventive concepts of the present invention by those skilled in the art within the technical scope of the present invention shall be covered by the scope of the present invention.
Claims (10)
1. The chlorine dioxide effervescent bomb is characterized by comprising a chlorine dioxide disinfection granule, wherein the outside of the chlorine dioxide disinfection granule is wrapped by an outer shell, and the chlorine dioxide disinfection granule comprises a component A and a component B; the component A comprises: 20-50 parts of chlorite, 0.5-5 parts of effervescent agent, 0.2-1 part of surfactant and A component adhesive; the component B comprises: 3-15 parts of acidifying agent, 0.5-5 parts of activating agent and 10-40 parts of component B adhesive, wherein the weight ratio of the component A adhesive to the component B adhesive is above.
2. The chlorine dioxide effervescent bomb according to claim 1, wherein the chlorite is one or a mixture of sodium chlorite, potassium chlorite, calcium chlorite and barium chlorite.
3. A chlorine dioxide effervescent pellet as claimed in claim 1, wherein the acidulant is one or a mixture of oxalic acid, succinic acid, citric acid, L-malic acid, phosphoric acid and tartaric acid.
4. A chlorine dioxide effervescent bomb as claimed in claim 1, wherein the activating agent is one or more of ammonium persulfate, lithium persulfate, potassium persulfate and sodium persulfate.
5. A chlorine dioxide effervescent bomb as claimed in claim 1, which is characterized in that the effervescent agent is one or more of sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate and magnesium carbonate.
6. A chlorine dioxide effervescent pellet as claimed in claim 1, wherein the surfactant is one or more selected from basic acetylene glycols, ethoxylated acetylene glycols, sodium dodecyl sulfate and sodium dodecyl benzene sulfonate.
7. A chlorine dioxide effervescent bomb as claimed in any one of claims 1 to 6, wherein the A component binder is one or a mixture of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000 and PVA 1788; the B component adhesive is one or a mixture of more of PVA1788, PVA1799, PEG2000, PEG4000, PEG6000, PVA1788, polyacrylic acid, pectin, water-soluble starch and guar gum.
8. A chlorine dioxide effervescent pellet as claimed in claim 7, wherein the formation of the chlorine dioxide disinfectant tablet comprises the following steps: weighing chlorite, effervescent agent, surfactant and A component adhesive in proportion and mixing to obtain a mixture A;
then, weighing the acidifying agent, the activating agent and the component B adhesive in proportion and mixing to obtain a mixture B;
and (3) mixing the mixture A, mixing the mixture B, and respectively adding the mixed mixture A and the mixed mixture B into a double-pipe feeding screw extruder for extrusion and granulation.
9. The chlorine dioxide effervescent bomb according to claim 8, wherein calcium chloride micro powder is added into the mixture A and/or the mixture B and then extruded;
when the mixture a is kneaded: the mixing temperature is 40-70 ℃, the feeding amount is 1-20Kg each time, the heating mode is electrical heating, the paddle is sigma type, the rotating speed N1 of the paddle is 15-25 revolutions per minute, the rotating speed N2 is 35-55 revolutions, and the materials are kneaded, discharged, cooled and crushed;
when the mixture B is mixed: the mixing temperature is 60-90 ℃, the feeding amount is 1-10Kg each time, the heating mode is electric heating, the paddle is sigma type, the rotating speed N1 of the paddle is 20-25 revolutions per minute, the rotating speed N2 is 40-50 revolutions, and the kneading, discharging, cooling and crushing are carried out;
the double-tube feeding screw extruder has the feeding section of room temperature, the compression section of 35-55 deg.c, the homogenizing section of 50-70 deg.c, the head and mouth mold section of 55-65 deg.c, water content in the material controlled to be less than or equal to 0.025%, screw rotation speed of 10-20 (r/min), flow stabilizing and setting section of 60-120mm length, drawing ratio of 0.95-1.2, extrusion mouth mold inner diameter of 0.5-2mm and cutting length of 0.5-2mm.
10. A chlorine dioxide effervescent pellet as claimed in any one of claims 1 to 6 and 8 to 9, wherein the outer shell material is one or more of methylcellulose, carboxymethylcellulose, pullulan cellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, chitosan, konjac glucomannan, gelatin and hydroxypropyl starch;
the outer shell includes public shell and female shell, public shell open end has the portion of inserting, female shell open end has the portion of establishing that the cover that supplies the portion of inserting to insert.
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| CN115777723A (en) * | 2023-02-07 | 2023-03-14 | 山东华实药业有限公司 | Instant chlorine dioxide effervescent tablet and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115777723A (en) * | 2023-02-07 | 2023-03-14 | 山东华实药业有限公司 | Instant chlorine dioxide effervescent tablet and preparation method thereof |
| CN115777723B (en) * | 2023-02-07 | 2023-04-07 | 山东华实药业有限公司 | Instant chlorine dioxide effervescent tablet and preparation method thereof |
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| Publication number | Publication date |
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| CN115517266B (en) | 2024-03-22 |
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