CN115501327A - Sleeping paste with emotion relieving and sleeping aiding functions - Google Patents

Sleeping paste with emotion relieving and sleeping aiding functions Download PDF

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Publication number
CN115501327A
CN115501327A CN202211036017.3A CN202211036017A CN115501327A CN 115501327 A CN115501327 A CN 115501327A CN 202211036017 A CN202211036017 A CN 202211036017A CN 115501327 A CN115501327 A CN 115501327A
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parts
sleep
extract
layer
ethanol
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朱登攀
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract

The invention provides a sleeping paste with a function of relieving emotion and helping sleep, which comprises a bottom layer, a graphene layer for soaking sleep-helping medicines, a filling layer and a fabric layer which are sequentially arranged from bottom to top, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer; the sleep-aiding medicine comprises the following components in parts by weight: 6-8 parts of angelica sinensis, 6-7 parts of arillus longan, 3-5 parts of liquorice, 2-4 parts of agilawood essential oil, 7-9 parts of spina date seeds, 6-9 parts of polygala tenuifolia, 2-4 parts of gamma-aminobutyric acid, 2-6 parts of collagen peptides, 1-5 parts of whey protein hydrolysate, 3-7 parts of motherwort extract and 5-7 parts of chamomile extract. The nerve calming patch plays a role in reducing blood pressure and helping sleep through physical action and medicinal action, is convenient to carry, and effectively solves the problems of simple function, long acting time, short duration and the like in the prior art.

Description

Sleeping paste with emotion relieving and sleeping aiding functions
Technical Field
The invention belongs to the technical field of sleeping patches, and particularly relates to a sleeping patch with a mood-relieving and sleep-aiding function.
Background
One third of the life of a person is spent in sleeping, and five days of non-sleep can affect the survival of the person, so that sleeping is one of the important physiological requirements of the person. However, due to the reasons of accelerated pace of life, rapid increase of life pressure, long-term contradiction of thoughts or heavy mental burden, mental labor, improper work and rest combined with long-term treatment, weakness after illness and the like, a part of people have sleep problems which become global problems, and many people suffer from the sleep problems of insomnia, difficulty in falling asleep, shallow sleep, easy awakening and the like to different degrees, so that the life quality of people is greatly influenced. At present, no effective method and medicine for treating insomnia exist, most people relieve insomnia by using sleeping pills of western medicines, and long-time taking of the sleeping pills produces dependence on the medicines, causes many toxic and side effects and seriously harms the health of people. Compared with western medicine oral treatment, the treatment effect of the traditional Chinese medicine is more stable and ideal, and the side effect is small, but the existing traditional Chinese medicine treatment method is mostly oral administration, is not convenient to carry and use, and simultaneously has simple function, long effect taking time, short duration and incapability of generating stronger effect.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides the sleeping patch with the functions of relieving emotion and helping sleep, which has the functions of reducing blood pressure and helping sleep through physical action and medicinal action, is convenient to carry, and effectively solves the problems of simple function, long acting time, short duration and the like in the prior art.
In order to achieve the purpose, the technical scheme adopted by the invention for solving the technical problems is as follows: the utility model provides a soporific patch with the functions of relieving emotion and helping sleep, which comprises a bottom layer, a graphene layer for soaking sleep-helping medicines, a filling layer and a fabric layer which are arranged from bottom to top in sequence, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer;
the sleep-aiding medicine comprises the following components in parts by weight: 6-8 parts of angelica sinensis, 6-7 parts of arillus longan, 3-5 parts of liquorice, 2-4 parts of agilawood essential oil, 7-9 parts of spina date seeds, 6-9 parts of polygala tenuifolia, 2-4 parts of gamma-aminobutyric acid, 2-6 parts of collagen peptides, 1-5 parts of whey protein hydrolysate, 3-7 parts of motherwort extract and 5-7 parts of chamomile extract.
Further, the sleep-aiding medicine comprises the following components in parts by weight: 7 parts of angelica sinensis, 6 parts of arillus longan, 4 parts of liquorice, 3 parts of agilawood essential oil, 8 parts of spina date seeds, 7 parts of polygala tenuifolia, 3 parts of gamma-aminobutyric acid, 4 parts of collagen peptide, 3 parts of whey protein hydrolysate, 5 parts of motherwort extract and 6 parts of chamomile extract.
Further, the motherwort extract is prepared by the following method: pulverizing herba Leonuri, soaking in mixed solution of hydrochloric acid and ethanol for 20-30 hr, and filtering to obtain first ethanol extractive solution; adding the filtered motherwort into ethanol, soaking for 20-30h, and filtering to obtain a second glycol extract; and (3) combining the first alcohol extract and the second alcohol extract, distilling under reduced pressure, purifying by using macroporous adsorption resin, washing and drying to obtain the motherwort herb extract.
Furthermore, the mass ratio of the motherwort to the hydrochloric acid is 1:1-2, and the concentration of the ethanol is 70-75wt%.
Further, the chamomile extract is prepared by the following method: crushing chamomile, heating and stirring the crushed chamomile twice by using 50vt% ethanol at the mass-volume ratio of 1:4 and 1:7 respectively at the temperature of 75-85 ℃, extracting the mixture twice, merging filtrate, and recovering ethanol until the filtrate is dry to obtain filter residue; purifying the filter residue with macroporous adsorbent resin, washing to colorless, eluting with 50vt% ethanol, adding active carbon into the eluate, refluxing and decolorizing for 20-40min, filtering, concentrating the decolorized solution, and spray drying to obtain flos Matricariae Chamomillae extract.
Further, the graphene layer soaked with the sleep-aiding medicine is prepared by the following method: drying and crushing angelica sinensis, arillus longan, liquorice, spina date seed and polygala tenuifolia, then performing reflux extraction for 1-3 times by using 50vt% ethanol, combining concentrated solutions, then adding agilawood essential oil, gamma-aminobutyric acid, collagen peptide, whey protein hydrolysate, a motherwort extract and a chamomile extract, then soaking the graphene layer for 6-12 hours, taking out, and performing vacuum drying for 2-4 hours at the temperature of 60-80 ℃ to obtain the graphene layer soaked with the sleep-aiding medicine.
Further, adhesive layers are arranged on two sides of the bottom layer.
The setting of gluing layer is the paste of the subsides of sleeping easily, can paste everywhere at the human body, and convenient to use is swift, low cost.
Further, a plurality of air holes are arranged on the bottom layer.
The arrangement of the air holes facilitates the medicine to act on the skin at the position where the patch is stuck for promoting sleep, and the effects of reducing blood pressure and helping sleep are achieved.
Further, the magnetic coating is prepared by the following method: and coating the ultraviolet curing coating containing the oleophilic ferrite nano-particles on the fabric layer, and performing ultraviolet curing to obtain the magnetic coating.
In summary, the invention has the following advantages:
1. the invention plays roles of relieving pressure, anxiety and calming through the combined action of physical action and medicinal action, improves sleep quality, promotes the effects of reducing blood pressure and helping sleep, has the effect of helping sleep continuously and evening, promotes blood circulation, improves sleep condition, is convenient to carry, and effectively solves the problems of simple function, long onset time, short duration and the like in the prior art.
2. When the graphene layer soaked with the sleep-aiding medicine is used, the graphene layer can absorb heat naturally radiated by a human body, and releases infrared rays to accelerate blood flow and improve the blood circulation condition of the human body; the radiated heat can also promote the transfer and accelerated transportation of the sleep-aiding medicine, shorten the onset time of the sleep-aiding medicine, quickly act, promote the release of the medicine effect of the medicine, give full play to the medicine, improve the sleep problem, accelerate the sleep and relieve the pain caused by the insomnia of a user. The invention also forms a magnetic field by arranging the magnetic sheets and the magnetic coating, can adjust the nervous system and the blood circulation by acting on human tissues through the magnetic field, has the effects of easing pain and removing blood stasis, has long duration of the magnetic field, can act for a long time all night, promotes the blood circulation, improves the sleep condition, changes the direction, reduces the replacement frequency of the soporific patch and reduces the use cost.
3. The product of the hydrolyzed whey protein contains peptides which have the function of regulating physiological functions, can play the roles of anesthesia and analgesia, makes people comfortable for the whole body, and is beneficial to relieving fatigue and helping sleep; the whey protein active peptide in the whey protein hydrolysate also has ACE inhibitory activity and has certain health-care and curative effects on human bodies. The gamma-aminobutyric acid can inhibit or block the over excitation of nerve cells, so that nerves are relaxed thoroughly, people feel comfortable for the whole body, and the fatigue is relieved and the sleep is promoted. The collagen peptide is used as an auxiliary material, has a synergistic effect with gamma-aminobutyric acid, has the effects of relieving pressure, anxiety and sedation, and plays a role in improving sleep.
4. The motherwort extract has the functions of reducing blood pressure and blood fat, can reduce the blood pressure and blood fat of a user in the sleep aiding process, can relieve the conditions of hypertension, hyperlipidemia and the like of the user after being used for many times, promotes the health preservation and health care of the user, and has the functions of promoting blood circulation, regulating menstruation, removing blood stasis and promoting tissue regeneration. The chamomile extract can relieve nervous mood, relieve pressure, improve impatient mood, and play a role in relieving tension and assisting sleep, and the licorice extract can also harmonize the medicines, so that the effects of the raw materials are fully synergistic, and the effects of reducing pressure and assisting sleep are enhanced. The agilawood essential oil can increase the fragrance of the sleep-aiding medicine, a user can be always in a comfortable fragrance environment without greasy feeling, the volatile cost of the agilawood essential oil has the effects of tranquilizing and the like, the anxiety of the user can be relieved, and the effects of calming and aiding sleep are achieved.
5. The Chinese angelica, the arillus longan, the liquorice, the spina date seed, the polygala tenuifolia and other medicines can be directly absorbed by skin to play a role in calming nerves and helping sleep, and the motherwort extract, the chamomile extract, the gamma-aminobutyric acid, the collagen peptide and the whey protein hydrolysate are combined to play a role in reducing blood pressure and blood fat and promoting sleep, so that the Chinese angelica, the arillus longan, the liquorice, the spina date seed, the polygala tenuifolia and other medicines have various functions, can play a role quickly, are long in lasting time, and are convenient to carry and use quickly.
Drawings
Fig. 1 is a sectional view of a sleeping patch with functions of reducing blood pressure and helping sleep.
Detailed Description
Example 1
A sleeping plaster with the functions of relieving emotion and assisting sleep comprises a bottom layer, a graphene layer for soaking sleep-assisting medicines, a filling layer and a fabric layer which are sequentially arranged from bottom to top, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer; the bottom layer is provided with a plurality of air holes.
The sleep-aiding medicine comprises the following components in parts by weight: 6 parts of angelica sinensis, 6 parts of arillus longan, 3 parts of liquorice, 2 parts of agilawood essential oil, 7 parts of spina date seed, 6 parts of polygala tenuifolia, 2 parts of gamma-aminobutyric acid, 2 parts of collagen peptide, 1 part of whey protein hydrolysate, 3 parts of motherwort extract and 5 parts of chamomile extract.
The motherwort extract is prepared by the following method: pulverizing herba Leonuri, soaking in mixed solution of hydrochloric acid and ethanol for 20 hr, and filtering to obtain first ethanol extractive solution; adding the filtered motherwort into ethanol, soaking for 20 hours, and filtering to obtain a second glycol extract; and (3) combining the first alcohol extract and the second alcohol extract, distilling under reduced pressure, purifying by using macroporous adsorption resin, washing and drying to obtain the motherwort herb extract. Wherein, the mass ratio of the motherwort to the hydrochloric acid is 1:1, and the ethanol concentration is 70wt%.
The chamomile extract is prepared by the following method: crushing chamomile, heating and stirring the crushed chamomile twice by using 50vt% ethanol at the mass-volume ratio of 1:4 and 1:7 respectively at the temperature of 75 ℃, extracting the mixture twice, merging filtrate, and recovering ethanol until the filtrate is dry to obtain filter residue; purifying the filter residue with macroporous adsorbent resin, washing to colorless, eluting with 50vt% ethanol, adding active carbon into the eluate, refluxing and decolorizing for 20min, filtering, concentrating the decolorized solution, and spray drying to obtain flos Matricariae Chamomillae extract.
The graphene layer soaked with the sleep-aiding medicine is prepared by the following method: drying and crushing angelica sinensis, arillus longan, liquorice, spina date seed and polygala tenuifolia, then performing reflux extraction for 1 time by 50vt% ethanol, merging concentrated solutions, then adding agilawood essential oil, gamma-aminobutyric acid, collagen peptide, whey protein hydrolysate, motherwort extract and chamomile extract, then soaking the graphene layer for 6 hours, taking out the graphene layer, and performing vacuum drying for 2 hours at the temperature of 60 ℃ to obtain the graphene layer soaked with the sleep-aiding medicine.
The magnetic coating is prepared by the following method: and coating the ultraviolet curing coating containing the oleophilic ferrite nano-particles on the fabric layer, and performing ultraviolet curing to obtain the magnetic coating.
Example 2
A soporific patch with emotion relieving and sleep aiding functions comprises a bottom layer, a graphene layer for soaking sleep aiding medicines, a filling layer and a fabric layer which are sequentially arranged from bottom to top, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer; the bottom layer is provided with a plurality of air holes.
The sleep-aiding medicine comprises the following components in parts by weight: 7 parts of angelica sinensis, 6 parts of arillus longan, 4 parts of liquorice, 3 parts of agilawood essential oil, 8 parts of spina date seeds, 7 parts of polygala tenuifolia, 3 parts of gamma-aminobutyric acid, 4 parts of collagen peptide, 3 parts of whey protein hydrolysate, 5 parts of motherwort extract and 6 parts of chamomile extract.
The motherwort extract is prepared by the following method: pulverizing herba Leonuri, soaking in mixed solution of hydrochloric acid and ethanol for 25 hr, and filtering to obtain first ethanol extractive solution; adding the filtered motherwort into ethanol, soaking for 25 hours, and filtering to obtain a second glycol extract; and (3) combining the first alcohol extract and the second alcohol extract, distilling under reduced pressure, purifying by using macroporous adsorption resin, washing and drying to obtain the motherwort herb extract. Wherein, the mass ratio of the motherwort to the hydrochloric acid is 1:1, and the ethanol concentration is 73wt%.
The chamomile extract is prepared by the following method: crushing chamomile, heating and stirring the crushed chamomile twice by using 50vt% ethanol at the mass-volume ratio of 1:4 and 1:7 respectively at 80 ℃, extracting the mixture twice, merging filtrate, and recovering ethanol until the filtrate is dry to obtain filter residue; purifying the filter residue with macroporous adsorbent resin, washing to almost colorless, eluting with 50vt% ethanol, adding active carbon into the eluate, refluxing and decolorizing for 30min, filtering, concentrating decolorized solution, and spray drying to obtain flos Matricariae Chamomillae extract.
The graphene layer soaked with the sleep-aiding medicine is prepared by the following method: drying and crushing angelica sinensis, arillus longan, liquorice, spina date seed and polygala tenuifolia, then performing reflux extraction for 2 times by using 50vt% ethanol, merging concentrated solutions, then adding agilawood essential oil, gamma-aminobutyric acid, collagen peptide, whey protein hydrolysate, a motherwort herb extract and a chamomile extract, then soaking the graphene layer for 9 hours, taking out the graphene layer, and performing vacuum drying for 3 hours at the temperature of 70 ℃ to obtain the graphene layer soaked with the sleep-aiding medicine.
The magnetic coating is prepared by the following method: and coating the ultraviolet curing coating containing the oleophilic ferrite nano-particles on the fabric layer, and performing ultraviolet curing to obtain the magnetic coating.
Example 3
A soporific patch with emotion relieving and sleep aiding functions comprises a bottom layer, a graphene layer for soaking sleep aiding medicines, a filling layer and a fabric layer which are sequentially arranged from bottom to top, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer; the bottom layer is provided with a plurality of air holes.
The sleep-aiding medicine comprises the following components in parts by weight: 8 parts of angelica sinensis, 7 parts of arillus longan, 5 parts of liquorice, 4 parts of agilawood essential oil, 9 parts of spina date seeds, 9 parts of polygala tenuifolia, 4 parts of gamma-aminobutyric acid, 6 parts of collagen peptide, 5 parts of whey protein hydrolysate, 7 parts of motherwort herb extract and 7 parts of chamomile extract.
The motherwort extract is prepared by the following method: pulverizing herba Leonuri, soaking in mixed solution of hydrochloric acid and ethanol for 30h, and filtering to obtain first ethanol extractive solution; adding the filtered motherwort into ethanol, soaking for 30 hours, and filtering to obtain a second glycol extract; and (3) combining the first alcohol extract and the second alcohol extract, distilling under reduced pressure, purifying by using macroporous adsorption resin, washing and drying to obtain the motherwort herb extract. Wherein, the mass ratio of the motherwort to the hydrochloric acid is 1:2, and the concentration of the ethanol is 75wt%.
The chamomile extract is prepared by the following method: crushing chamomile, heating and stirring and extracting twice by using 50vt% ethanol at 85 ℃ according to mass-volume ratios of 1:4 and 1:7 respectively, merging filtrates, and recovering ethanol till dryness to obtain filter residue; purifying the filter residue with macroporous adsorbent resin, washing to almost colorless, eluting with 50vt% ethanol, adding active carbon into the eluate, refluxing and decolorizing for 40min, filtering, concentrating decolorized solution, and spray drying to obtain flos Matricariae Chamomillae extract.
The graphene layer soaked with the sleep-aiding medicine is prepared by the following method: drying and crushing angelica sinensis, arillus longan, liquorice, spina date seed and polygala tenuifolia, then performing reflux extraction for 3 times by using 50vt% ethanol, combining concentrated solutions, then adding agilawood essential oil, gamma-aminobutyric acid, collagen peptide, whey protein hydrolysate, a motherwort herb extract and a chamomile extract, then soaking the graphene layer for 12 hours, taking out the graphene layer, and performing vacuum drying for 4 hours at the temperature of 80 ℃ to obtain the graphene layer soaked with the sleep-aiding medicine.
The magnetic coating is prepared by the following method: and coating the ultraviolet curing coating containing the oleophilic ferrite nano-particles on the fabric layer, and performing ultraviolet curing to obtain the magnetic coating.
Comparative example 1
Comparative example 1 and example 2 differ in that no collagen peptide is contained.
Comparative example 2
Comparative example 2 differs from example 2 in that no whey protein hydrolysate is present.
Comparative example 3
Comparative example 3 is different from example 2 in that motherwort extract is not contained.
Comparative example 4
Comparative example 4 differs from example 2 in that it does not contain chamomile extract.
Examples of the experiments
1. Experimental case
The experimental cases are 280 outpatient cases from 8 months to 12 months in 2019, wherein 145 men, 135 women, 20-65 years old, 2-3 years old in course and 1 month of treatment period do not use related medicines.
2. Experimental methods
The 270 cases were divided into 7 groups of 40 persons, and there was no significant difference in sex, age, and course of disease among the groups. The sleeping patches of examples 1 to 3 of the present invention were used in experimental groups 1 to 3, respectively, and the sleeping patches of comparative examples 1 to 4 were used in control groups 1 to 4, respectively, and the sleeping patches were attached to the temple one at night and removed the morning the next day.
15 days are 1 course, and each group has 2 continuous courses.
3. Standard of therapeutic effect and standard of therapeutic effect of therapeutic result
Referring to an international standard unified sleep efficiency value formula: sleep rate = (actual time to fall asleep/total time to get up x 100%). Where the actual time to fall asleep corresponds to the duration of the insomnia indicator.
And (3) healing: the symptoms disappear, and the sleep rate reaches more than 75 percent (under the condition of stopping the treatment means).
The effect is shown: the symptoms are relieved, and the sleep rate reaches more than 65 percent (under the condition of stopping the treatment means).
The method has the following advantages: the symptoms are improved, and the sleep rate reaches more than 55 percent (under the condition of stopping the treatment means).
And (4) invalidation: the symptoms are as before, and the sleep rate is below 40%.
The therapeutic effect is shown in table 1.
TABLE 1 statistical table of treatment effect of experimental cases
Experimental group 1 Experimental group 2 Experimental group 3 Control group 1 Control group 2 Control group 3 Control group 4
Rate of recovery/%) 12.5 15 12.5 0 0 0 0
Significant efficiency/%) 25 30 27.5 7.5 10 10 7.5
Effective rate% 63 52.5 55 52.5 57.5 55 55
Non efficiency/%) 5 2.5 5 40 32.5 35 37.5
Total effective rate/%) 95 97.5 95 60 67.5 65 62.5
As can be seen from table 1, after the sedative patch of the present invention is used, the total effective rate is above 95%, the sedative patch has the effects of relieving stress, anxiety and sedation, improving sleep quality, promoting blood pressure reduction and sleep aid, and significantly improving sleep conditions. The contrast groups 1-4 lack corresponding key components, so the total quality effect is obviously inferior to that of the experimental groups 1-3, the maximum total effective rate is 67.5 percent, and the difference is about 30 percent from that of the experimental groups. The control groups 1-4 are not added with collagen peptide, whey protein hydrolysate, motherwort extract and chamomile extract respectively, the treatment effect is obviously poor, so that the corresponding components in the nerve soothing patch play a key role, the components are synergistic, the effects of reducing blood pressure and helping sleep are achieved, the effect is obvious, and the treatment effect of insomnia is improved; the nerve soothing patch is convenient to carry and use, and is favorable for popularization and use.
While the present invention has been described in detail with reference to the illustrated embodiments, it should not be construed as limited to the scope of the present patent. Various modifications and changes may be made by those skilled in the art without inventive step within the scope of the appended claims.

Claims (9)

1. A sleeping paste with functions of relieving emotion and helping sleep is characterized by comprising a bottom layer, a graphene layer for soaking sleep-helping medicines, a filling layer and a fabric layer which are sequentially arranged from bottom to top, wherein the fabric layer is coated with a magnetic coating, and a plurality of magnetic sheets are arranged in the filling layer;
the sleep-aiding medicine comprises the following components in parts by weight: 6-8 parts of angelica sinensis, 6-7 parts of arillus longan, 3-5 parts of liquorice, 2-4 parts of agilawood essential oil, 7-9 parts of spina date seeds, 6-9 parts of polygala tenuifolia, 2-4 parts of gamma-aminobutyric acid, 2-6 parts of collagen peptides, 1-5 parts of whey protein hydrolysate, 3-7 parts of motherwort extract and 5-7 parts of chamomile extract.
2. The patch with the functions of reducing blood pressure and helping sleep as claimed in claim 1, wherein the sleep-helping medicine comprises the following components in parts by weight: 7 parts of angelica sinensis, 6 parts of arillus longan, 4 parts of liquorice, 3 parts of agilawood essential oil, 8 parts of spina date seeds, 7 parts of polygala tenuifolia, 3 parts of gamma-aminobutyric acid, 4 parts of collagen peptide, 3 parts of whey protein hydrolysate, 5 parts of motherwort extract and 6 parts of chamomile extract.
3. A patch for promoting sleep and lowering blood pressure as claimed in claim 1 or 2, wherein the extract of motherwort is prepared by the following method: pulverizing herba Leonuri, soaking in mixed solution of hydrochloric acid and ethanol for 20-30 hr, and filtering to obtain first ethanol extractive solution; adding the filtered motherwort into ethanol, soaking for 20-30h, and filtering to obtain a second glycol extract; and (3) combining the first alcohol extract and the second alcohol extract, distilling under reduced pressure, purifying by using macroporous adsorption resin, washing and drying to obtain the motherwort herb extract.
4. A patch for promoting sleep and lowering blood pressure as claimed in claim 3, wherein the mass ratio of herba Leonuri to hydrochloric acid is 1:1-2, and the ethanol concentration is 70-75wt%.
5. A patch for improving sleep and lowering blood pressure according to claim 1 or 2, wherein the chamomile extract is prepared by the following method: crushing chamomile, heating and stirring the crushed chamomile twice by using 50vt% ethanol at the mass-volume ratio of 1:4 and 1:7 respectively at the temperature of 75-85 ℃, extracting the mixture twice, merging filtrate, and recovering ethanol until the filtrate is dry to obtain filter residue; purifying the filter residue with macroporous adsorbent resin, washing to colorless, eluting with 50vt% ethanol, adding active carbon into the eluate, refluxing and decolorizing for 20-40min, filtering, concentrating the decolorized solution, and spray drying to obtain flos Matricariae Chamomillae extract.
6. A patch for promoting sleep and lowering blood pressure as claimed in claim 1, wherein the graphene layer soaked with sleep-aid drug is prepared by the following method: drying and crushing angelica sinensis, arillus longan, liquorice, spina date seed and polygala tenuifolia, then performing reflux extraction for 1-3 times by using 50vt% ethanol, combining concentrated solutions, then adding agilawood essential oil, gamma-aminobutyric acid, collagen peptide, whey protein hydrolysate, a leonurus extract and a chamomile extract, then soaking graphene layers for 6-12 hours, taking out, and performing vacuum drying for 2-4 hours at the temperature of 60-80 ℃ to obtain the graphene layers soaked with the sleep-aiding medicine.
7. A patch for promoting sleep and lowering blood pressure as claimed in claim 1, wherein the bottom layer is provided with adhesive layers on both sides.
8. A patch for promoting sleep and lowering blood pressure as claimed in claim 1, wherein said bottom layer has a plurality of air holes.
9. A patch for promoting sleep and lowering blood pressure as claimed in claim 1, wherein said magnetic coating layer is prepared by the following method: and coating the ultraviolet curing coating containing the oleophilic ferrite nano-particles on the fabric layer, and performing ultraviolet curing to obtain the magnetic coating.
CN202211036017.3A 2022-08-27 2022-08-27 Sleeping paste with emotion relieving and sleeping aiding functions Pending CN115501327A (en)

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