CN115487126A - Blackhead-removing traditional Chinese medicine composition and application thereof - Google Patents

Blackhead-removing traditional Chinese medicine composition and application thereof Download PDF

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CN115487126A
CN115487126A CN202210779861.9A CN202210779861A CN115487126A CN 115487126 A CN115487126 A CN 115487126A CN 202210779861 A CN202210779861 A CN 202210779861A CN 115487126 A CN115487126 A CN 115487126A
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extract
traditional chinese
chinese medicine
ethanol
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刘宇
李俊慧
谢清华
孟琪
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Shandong Boke Medical Materials Co ltd
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Shandong Boke Medical Materials Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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Abstract

The invention belongs to the technical field of cosmetics, and relates to a blackhead removing traditional Chinese medicine composition and application thereof; the components of the traditional Chinese medicine composition for removing blackheads comprise cyperus rotundus extract, radix sileris extract, white peony root extract, astragalus extract, radix scrophulariae extract, 1, 3-butanediol, glycerol, sodium hyaluronate, arginine, carbomer, panthenol, betaine, dipotassium glycyrrhizinate and the like; cyperus rotundus for drying blackhead grease; the divaricate saposhnikovia root is pungent and dry, and can drain damp soil, can move channels and collaterals, and can dredge blocked skin channels and collaterals; white peony root is sour in flavor, has the same work and effect as brush acid, and can purge heat of skin nutrient and blood; astragalus root is good at restoring skin, tonifying lung qi, and accelerating dissolution and discharge of blackheads; the figwort is used for clearing away heat and replenishing water; cyperus rotundus and Ledebouriella root, radix Aconiti lateralis Preparata and Ledebouriella root, radix Saposhnikoviae, which are used together as monarch drugs, clear lung heat and dredge meridians. The radix paeoniae alba and the radix astragali are mainly used for solving the 'target' disease, the radix scrophulariae is used for assisting the cyperus rotundus, the radix paeoniae alba and the radix astragali are used as ministerial medicines, the traditional Chinese medicines are compounded and applied to cosmetics for external use of skin, and the effects of removing blackheads and moistening the skin are achieved cooperatively.

Description

Blackhead-removing traditional Chinese medicine composition and application thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a blackhead removing traditional Chinese medicine composition and application thereof.
Background
Modern people have become more and more common skin problems, especially blackheads, due to over-clean skin, improvement of living conditions, irregular daily work and rest and excessive secretion of sebaceous glands in bodies.
At present, the main methods for removing blackheads in the market comprise a suction tube method, a frosting method, a nose pasting method, an acid brushing method and the like, have certain effects, but are easy to stimulate, cause sensitive skin and have professional operation requirements.
The traditional Chinese medicine considers that the lung governs the skin, the occurrence of skin problems is closely related to the lung, in addition, the blockage of blackheads can cause the occurrence of skin grease excessive secretion, local redness and other inflammations, and the lung heat, blood heat and moisture excess belong to the traditional Chinese medicine, so the treatment mainly aims at eliminating dampness, clearing lung heat and nourishing blood heat.
The active ingredients of the traditional Chinese medicine can be exerted to a greater extent in the cosmetics, but the research on the similar traditional Chinese medicine ingredients for removing blackheads is less at present, and the traditional Chinese medicine ingredients are few in the field of external application.
Therefore, the problem to be solved at present is to find a blackhead-removing traditional Chinese medicine composition which exerts the traditional Chinese medicine value and realizes the application of the blackhead-removing traditional Chinese medicine composition in cosmetics external application.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine composition for removing blackheads, which is used for removing lung components in the chest and skin and hair components in the lung, and cyperus rotundus can remove heat and skin hair in the chest, has fragrant and dry smell, can dry blackhead grease, and can be used for radical direct attack; the divaricate saposhnikovia root is pungent and dry, can drain damp soil, can pass through channels and collaterals, dispels dampness, can dredge blocked skin channels and collaterals, and can also eliminate dampness to treat excess grease generated by blackhead blockage; the white peony root is sour in taste, is opposite to blackheads, has the wonderful effect of being different from that of brushing acid, can purge the heat of skin nutrient blood, can relieve the symptoms of local redness, and has the effect of diminishing inflammation; the astragalus membranaceus can well reach the skin, tonify lung qi and accelerate the dissolution and discharge of blackheads; figwort root, radix scrophulariae and radix scrophulariae, with the effects of clearing away heat from heart and chest, helps Cyperus rotundus clear lung heat; cyperus rotundus and Ledebouriella root, radix Ledebouriellae are monarch drugs for clearing lung-heat and dredging channels and collaterals. The radix paeoniae alba and the radix astragali are mainly used for solving secondary 'target' symptoms, the radix scrophulariae is used for assisting the rhizoma cyperi, the radix paeoniae alba, the radix astragali and the radix scrophulariae are used as ministerial drugs, the traditional Chinese medicines are compounded and applied to cosmetics for external use on the skin, and the effects of removing blackheads and moistening the skin are achieved in a synergistic mode.
In the invention, the composition of the cyperus rotundus extract, the divaricate saposhnikovia root extract, the white paeony root extract, the astragalus root extract and the figwort root extract is collectively called as the traditional Chinese medicine extract.
Specifically, the technical scheme of the invention is as follows:
a blackhead removing traditional Chinese medicine composition comprises the following components in percentage by weight: 1 to 1.5 percent of cyperus rotundus extract, 1 to 1.5 percent of divaricate saposhnikovia root extract, 0.8 to 1 percent of white paeony root extract, 1 to 1.5 percent of astragalus extract, 0.2 to 0.5 percent of figwort root extract, 1 to 2 percent of 1, 3-butanediol, 0.5 to 1 percent of glycerol, 0.1 to 0.2 percent of sodium hyaluronate, 0.1 to 0.2 percent of arginine, 0.1 to 0.2 percent of carbomer, 0.5 to 1 percent of panthenol, 0.3 to 0.5 percent of betaine, 0.1 to 0.15 percent of dipotassium glycyrrhizinate, 0.5 to 1 percent of preservative, and the balance of water added to 100 percent.
Further, the preparation method of the cyperus rotundus extract comprises the following steps: according to the weight percentage of ethanol: the preparation method comprises the following steps of (1) taking ethanol with the mass concentration of 50% as a solvent, heating and extracting the cyperus rotundus for 3-5 times, merging ethanol extract, cooling and precipitating for layering, and taking supernatant to obtain a cyperus rotundus extract;
further, the preparation method of the divaricate saposhnikovia root extract comprises the following steps: according to the weight percentage of ethanol: heating, extracting with ethanol with the mass concentration of 70% as a solvent according to the weight ratio of divaricate saposhnikovia root =5, extracting with the divaricate saposhnikovia root by refluxing for 3-5 times, combining the ethanol extract, cooling, precipitating and layering, and taking supernatant to obtain a divaricate saposhnikovia root extract;
further, the preparation method of the astragalus extract comprises the following steps: according to the weight ratio of ethanol: the preparation method comprises the following steps of (1) taking ethanol with the mass concentration of 50% as a solvent, heating and extracting the astragalus membranaceus with ethanol for 3-5 times, combining ethanol extract, cooling and precipitating for layering, and taking supernatant to obtain an astragalus membranaceus extract;
further, the preparation method of the figwort root extract comprises the following steps: according to the weight percentage of ethanol: figwort =7, using 90% ethanol of mass concentration as a solvent, heating and extracting figwort with ethanol for 2-3 times, merging ethanol extract, cooling and precipitating for layering, and taking supernatant to obtain the figwort extract.
Preferably, the blackhead removing traditional Chinese medicine composition comprises the following components in percentage by weight: 1% of cyperus rotundus extract, 1% of divaricate saposhnikovia root extract, 0.8% of white paeony root extract, 1% of astragalus extract, 0.5% of radix scrophulariae extract, 1-2% of 1, 3-butanediol, 0.5-1% of glycerol, 0.1-0.2% of sodium hyaluronate, 0.1-0.2% of arginine, 0.1-0.2% of carbomer, 0.5-1% of panthenol, 0.3-0.5% of betaine, 0.1-0.15% of dipotassium glycyrrhizinate, 0.5-1% of preservative and the balance of water, wherein the balance is added to 100%.
Wherein the preservative is a mixture of p-hydroxyacetophenone and hexanediol.
The invention also provides a preparation method of the blackhead removing traditional Chinese medicine composition, which comprises the following steps:
(1) Heating the water phase to 80-85 ℃, sequentially adding 1, 3-butanediol, glycerol, carbomer, dipotassium glycyrrhizinate and sodium hyaluronate in the process of heating, and emulsifying and homogenizing for 90s when adding one component each;
(2) Cooling to 40-45 ℃, and sequentially adding panthenol, betaine, dipotassium glycyrrhizinate, p-hydroxyacetophenone, cyperus rotundus extract, radix sileris extract, white peony root extract, astragalus extract and figwort root extract;
(3) Adding arginine, and adjusting the pH value to 5.5-6.0 to obtain the blackhead removing traditional Chinese medicine composition.
The invention also provides application of the blackhead removing traditional Chinese medicine composition in skin external cosmetics.
Preferably, the external skin cosmetic comprises essence, cream, lotion and gel.
The invention has the following beneficial effects:
the blackhead removing traditional Chinese medicine composition disclosed by the invention has the main components of traditional Chinese medicine raw material extracts, can effectively remove blackheads on the face of a user, does not contain irritant substances, is compounded with sodium hyaluronate, panthenol and the like, can be mutually matched and synergized, has good blackhead leading-out and convergence relieving effects, namely can effectively remove accumulated cutin, dredge blocked sebaceous glands, dissolve and float the blackheads, and can clean and control oil, inhibit bacteria and remove acnes, converge pores and restore the problem skin to be fresh and transparent.
Detailed Description
The invention is described below by means of specific embodiments. Unless otherwise specified, the technical means used in the present invention are well known to those skilled in the art. In addition, the embodiments should be considered illustrative, and not restrictive, of the scope of the invention, which is defined solely by the claims. It will be apparent to those skilled in the art that various changes or modifications in the components and amounts of the materials used in these embodiments can be made without departing from the spirit and scope of the invention.
The invention uses some components and manufacturers as follows:
table 1 part of the reagents and the manufacturers used in the examples
1, 3-butanediol Shandong Haikexin Source Material Technology Co., Ltd.
Hyaluronic acid sodium salt Shandong Focus Furuida Biological Co., Ltd.
Glycerol P.T.Musim Mas
Panthenol BASF CHINA Co.,Ltd.
Betaine Jinan Rui Shell Biotechnology Ltd
Glycyrrhizic acid dipotassium salt GANSU FANZHI PHARMACEUTICAL Co.,Ltd.
P-hydroxyacetophenone SHANGHAI HOPE-TEC BIOTECHNOLOGY Inc.
Carbomer LUBRIZOL ADVANCED MATERIALS, Inc.
Arginine WUXI JINGHAI AMINO ACID Co.,Ltd.
In some preferred embodiments of the present invention, the composition comprises the following components in percentage by weight:
Figure RE-GDA0003933506880000041
Figure RE-GDA0003933506880000051
example 1
The preparation method of the traditional Chinese medicine extract comprises the following steps:
the preparation method of the cyperus rotundus extract comprises the following steps: according to the weight percentage of ethanol: taking ethanol with the mass concentration of 50% as a solvent, heating and extracting 50g of cyperus rotundus powder by ethanol at 80 ℃, refluxing and extracting for 3 times, combining the ethanol extract, cooling for 30min, precipitating and layering, and taking supernatant to obtain a cyperus rotundus extract;
the preparation method of the divaricate saposhnikovia root extract comprises the following steps: according to the weight percentage of ethanol: divaricate saposhnikovia root =5, ethanol with the mass concentration of 70% is used as a solvent, 50g of divaricate saposhnikovia root is heated and extracted by ethanol at 80 ℃, the reflux extraction is carried out for 5 times, the ethanol extract is combined, the mixture is cooled for 20min, the precipitate is layered, and the supernatant is taken to obtain the divaricate saposhnikovia root extract;
the preparation method of the astragalus extract comprises the following steps: according to the weight percentage of ethanol: the weight ratio of astragalus =8, taking 50% ethanol with mass concentration as a solvent, heating and extracting 50g of astragalus with ethanol at 80 ℃, refluxing and extracting for 3 times, combining ethanol extract, cooling for 20min, precipitating and layering, and taking supernate to obtain an astragalus extract;
the preparation method of the figwort root extract comprises the following steps: according to the weight percentage of ethanol: the weight ratio of radix scrophulariae =7 and 90% ethanol in mass concentration as a solvent is adopted, 10g of radix scrophulariae is heated and extracted by ethanol at 80 ℃, reflux extraction is carried out for 2 times, ethanol extract is combined, cooling is carried out for 60min, precipitation and layering are carried out, and supernate is taken, so that the radix scrophulariae extract is obtained.
The preparation method of the blackhead removing traditional Chinese medicine composition comprises the following steps:
the "%" is weight percentage.
(1) Heating the water phase to 80 deg.C, sequentially adding 1, 3-butanediol, 0.5% glycerol, 0.1% carbomer, 0.1% dipotassium glycyrrhizinate, and 0.15% sodium hyaluronate, emulsifying and homogenizing for 90s;
(2) Cooling to 40 deg.C, sequentially adding 2% panthenol, 0.3% betaine, 0.5% p-hydroxyacetophenone, 0.2% hexanediol, 1% rhizoma Cyperi extract, 1% radix Saposhnikoviae extract, 0.8% radix Paeoniae alba extract, 1% radix astragali extract, and 0.5% radix scrophulariae extract;
(3) Adding arginine, and adjusting pH to 5.5 to obtain the blackhead removing traditional Chinese medicine composition.
The preparation method of the blackhead removing traditional Chinese medicine composition only needs to mix the components, and the process flow is simple and easy to operate. The moisturizing thickening component is cooperated with the traditional Chinese medicine extract, so that the stability of the system is enhanced, the active ingredients are slowly released for a long time, and the permeability, the mildness and the efficacy of the product are improved.
The amount of each component is not limited to the specific value, and the ratio of the corresponding components is within the protection scope of the present invention.
Example 2
The preparation method of the blackhead removing traditional Chinese medicine composition comprises the following steps:
the "%" is weight percent.
(1) Heating the water phase to 85 deg.C, sequentially adding 1% (by weight) of 1, 3-butanediol, 1% glycerol, 0.15% carbomer, 0.1% dipotassium glycyrrhizinate, and 0.15% sodium hyaluronate, emulsifying and homogenizing for 90s;
(2) Cooling to 45 deg.C, sequentially adding 1% panthenol, 0.3% betaine, 0.5% p-hydroxyacetophenone, 0.2% hexanediol, 1.5% rhizoma Cyperi extract, 1% radix Saposhnikoviae extract, 0.8% radix Paeoniae alba extract, 1.5% radix astragali extract, and 0.2% radix scrophulariae extract;
(3) Adding arginine, and adjusting pH to 5.6 to obtain the blackhead removing traditional Chinese medicine composition.
The extraction procedure of the herb extracts was the same as in example 1.
Example 3
The preparation method of the blackhead removing traditional Chinese medicine composition comprises the following steps:
the "%" is weight percent.
(1) Heating the water phase to 85 deg.C, sequentially adding 1% (by weight) of 1, 3-butanediol, 1% glycerol, 0.15% carbomer, 0.1% dipotassium glycyrrhizinate, and 0.15% sodium hyaluronate, emulsifying and homogenizing for 90s;
(2) Cooling to 45 deg.C, sequentially adding 1% panthenol, 0.3% betaine, 0.5% p-hydroxyacetophenone, 0.2% hexanediol, 1% rhizoma Cyperi extract, 1.5% radix Saposhnikoviae extract, 1% radix Paeoniae alba extract, 1.5% radix astragali extract, and 0.2% radix scrophulariae extract;
(3) Adding arginine, and adjusting the pH value to 5.6 to obtain the blackhead removing traditional Chinese medicine composition.
The extraction procedure of the herb extracts was the same as in example 1.
Comparative example 1
Except that all the traditional Chinese medicine extracts are not added, the formula components and the preparation steps of the traditional Chinese medicine composition for removing blackheads in the comparative example 1 are the same as those in the example 1, and the traditional Chinese medicine extracts are supplemented by water in percentage by weight.
Comparative example 2
Except that the white paeony root extract is not added, the formula components and the preparation steps of the traditional Chinese medicine composition for removing blackheads in the comparative example 2 are the same as those in the example 1, and the white paeony root extract accounts for the weight percentage which is supplemented by water.
Comparative example 3
The preparation method of the blackhead removing traditional Chinese medicine composition comprises the following steps:
the "%" is weight percentage.
(1) Heating the water phase to 85 deg.C, adding 1% of 1, 3-butanediol, 1% glycerol in sequence during heating process, emulsifying and homogenizing for 90s each component;
(2) Cooling to 45 deg.C, sequentially adding 0.5% p-hydroxyacetophenone, 0.2% hexanediol, 1% rhizoma Cyperi extract, 3% radix Saposhnikoviae extract, 0.5% radix Paeoniae alba extract, 0.1% radix astragali extract, and 0.2% radix scrophulariae extract;
(3) Adding arginine, and adjusting pH to 5.6 to obtain the blackhead removing traditional Chinese medicine composition.
The extraction procedure of the herb extracts was the same as in example 1.
The main component of the comparative example 3 is a traditional Chinese medicine extract, and the water replenishing and moisturizing components are reduced.
Evaluation of blackhead-removing efficacy
1. Black head clearance test: the blackhead removing rate test is carried out on the blackhead removing traditional Chinese medicine compositions obtained in the examples 1 to 3 and the comparative examples 1 to 3.
The experimental method comprises the following steps:
26 volunteers with oily skin and blackheads on the nose are selected, the age is 20-36 years, and the male and female are half-old. The volunteers could not use any blackhead removing product such as cosmetics, external medicines or health products for oral administration 30 days before the start of the test. Before the test, the nose is placed in a constant temperature and humidity room with the temperature of 22 +/-2 ℃ and the humidity of 45 +/-5% for standing for 30min, and then the nose part of the volunteer is photographed on the first day (D1). Randomly selecting the left and right noses of a volunteer, requiring the test subject to randomly use samples on one side of the left and right noses respectively, wherein one side is an embodiment and the other side is a comparative example, cleaning after applying for 15min, lightly scraping for a plurality of times by using a cotton swab, taking a picture on the same part of the volunteer again, and then performing labeling comparison by using pictures taken twice. The product was subsequently used 1 time per week and the test was asked to be carried out on day 7 (D7) and day 12 (D12) of the test.
And recording the number of the black heads and calculating the change rate.
Rate of change = (initial number of black spots-number of black spots after cleaning)/initial number of black spots × 100%
The results of the rate of change tests for the above application examples and comparative application examples are shown in table 3:
table 3 black head removing effect of the black head removing Chinese medicinal composition of each example and comparative example
Using sample/test cycle D1 D7 D12
Example 1 75.3% 85.4% 87.2%
Example 2 76.5% 83.5% 84.3%
Example 3 75.1% 81.3% 83.6%
Comparative example 1 35.8% 36.2% 36.5%
Comparative example 2 50.4% 64.0% 72.1%
Comparative example 3 62.4% 67.8% 78.3%
According to the trial test data, the blackhead removing traditional Chinese medicine composition prepared in the embodiments 1-3 has the advantages of high blackhead removing rate on skin, obvious blackhead removing effect, mild medicinal effect and no side effect, the components in the comparative example 1 lack traditional Chinese medicine extracts, the traditional Chinese medicine active substance has no efficacy, the blackhead removing effect is obviously reduced, the traditional Chinese medicine extracts in the comparative example 2 lack white paeony root extracts, the obtained blackhead removing composition has a poor effect, and the comparative example 1 and the comparative example 2 are combined, so that the synergistic effect is realized among the components of the composite traditional Chinese medicine; the formula in the comparative example 3 adjusts the dosage of the moisturizing thickening component and the traditional Chinese medicine extract component, which is not in the scope of the invention, so that the compatibility of the traditional Chinese medicine components is changed, the synergistic effect disappears, and the blackhead removing effect is obviously reduced.
Evaluation of product safety
The products of the examples 1 to 3 and the comparative examples 1 to 3 meet the relevant requirements of QB/T1857-2013, the sensory indexes (color, aroma and structure) meet the industrial regulations, and the physical and chemical indexes (pH, heat resistance, cold resistance and active substances) meet the industrial regulations.
The human skin patch test is as follows:
test products: the blackhead removing traditional Chinese medicine composition is prepared in each embodiment and comparative examples 1-2;
number of test population: 25 people, female;
age: between 25 and 48 years old;
health conditions are as follows: the skin of the subject is healthy, has no allergic history of skin diseases, and meets the volunteer selection standard of the subject;
grouping: 5 groups of 5 people each, mean age 33 years.
The spot pasting method comprises the following steps: a qualified spot tester is selected, about 1mL of a tested object is dripped into the spot tester in a closed spot patch test mode, a special adhesive tape is externally applied to the back of a tested object, the tested object is removed after 24 hours, skin reactions are observed for 0.5 hour, 6 hour, 12 hour, 24 hour and 48 hour after the tested object is removed respectively, and the results are recorded according to the skin reaction grading standard in the cosmetic sanitation Specification.
The experimental results are as follows: the result of the human body skin patch test shows that: each group of subjects can observe skin reactions at 0.5, 6, 12, 24 and 48h through the spot sticking test of the blackhead removing traditional Chinese medicine composition in the embodiment 1 to 3, wherein 0 case has adverse skin reactions, which indicates that the blackhead removing traditional Chinese medicine composition is safe to use.
The consumer questionnaire is specific for the product of the invention as follows:
the questionnaire survey of 35 subjects is selected, wherein the effective subjects are 33 subjects, the age range is 18-60 years, and the average age is 25 years; the 33 subjects used the product as required at the specified time without any adverse reaction.
Evaluation was performed using 7 days:
TABLE 5 questionnaire survey of Subjects
Figure RE-GDA0003933506880000111
Note: 5. 4, 3, 2, 1 points are respectively good, normal, poor
As can be seen from the above table, the blackhead removing traditional Chinese medicine compositions of embodiments 1 to 3 of the present invention are widely accepted by the subjects, and the subjects all show that the blackhead removing traditional Chinese medicine compositions of the present invention have good permeability, are easy to absorb, and have a good blackhead removing effect after use, and the embodiments 1 to 3 have advantages, and the users can select various formulations according to different situations.
The product in the comparative example 1 lacks the traditional Chinese medicine extract components in the invention, and the blackhead removing effect is inferior to that in the examples 1-3, which shows that the traditional Chinese medicine extract components are the main components of the blackhead removing effect, and the product in the comparative example 3 is obviously affected in blackhead removing capability after lacking the synergistic moisturizing and moisturizing components, mainly because the traditional Chinese medicine extract is not easily absorbed by skin and needs to be cooperated with other components of the formula of the invention to play a role.
Meanwhile, no allergy phenomenon occurs in all the subjects, and the conditions of skin itch, stabbing pain, red swelling and the like do not occur. Therefore, the blackhead removing composition is mild and safe and can be used for a long time.

Claims (10)

1. The blackhead removing traditional Chinese medicine composition is characterized by comprising the following components in percentage by weight: 1 to 1.5 percent of cyperus rotundus extract, 1 to 1.5 percent of divaricate saposhnikovia root extract, 0.8 to 1 percent of white paeony root extract, 1 to 1.5 percent of astragalus extract, 0.2 to 0.5 percent of figwort root extract, 1 to 2 percent of 1, 3-butanediol, 0.5 to 1 percent of glycerol, 0.1 to 0.2 percent of sodium hyaluronate, 0.1 to 0.2 percent of arginine, 0.1 to 0.2 percent of carbomer, 0.5 to 0.2 percent of panthenol, 0.3 to 0.5 percent of betaine, 0.1 to 0.15 percent of dipotassium glycyrrhizinate, 0.5 to 1 percent of preservative, and the balance of water added to 100 percent.
2. The blackhead removing traditional Chinese medicine composition as claimed in claim 1, wherein the preparation method of the cyperus rotundus extract comprises the following steps: according to the weight percentage of ethanol: the method comprises the following steps of (1) taking ethanol with the mass concentration of 50% as a solvent, heating and extracting cyperus rotundus in an alcohol manner, carrying out reflux extraction for 3-5 times, combining alcohol extract, cooling and precipitating for layering, and taking supernate to obtain the cyperus rotundus extract.
3. The blackhead removing traditional Chinese medicine composition as claimed in claim 1, wherein the preparation method of the divaricate saposhnikovia root extract comprises the following steps: according to the weight percentage of ethanol: the preparation method comprises the following steps of (1) taking ethanol with the mass concentration of 70% as a solvent according to the weight ratio of divaricate saposhnikovia root =5, heating, extracting the divaricate saposhnikovia root by ethanol, refluxing and extracting for 3-5 times, combining ethanol extract, cooling and precipitating for layering, and taking supernate to obtain the divaricate saposhnikovia root extract.
4. The blackhead removing traditional Chinese medicine composition as claimed in claim 1, wherein the preparation method of the astragalus extract comprises the following steps: according to the weight ratio of ethanol: the weight ratio of astragalus =8, taking 50% ethanol of mass concentration as a solvent, heating and extracting the astragalus membranaceus with ethanol, refluxing and extracting for 3-5 times, combining ethanol extract, cooling and precipitating for layering, and taking supernatant to obtain the astragalus membranaceus extract.
5. The blackhead-removing traditional Chinese medicine composition as claimed in claim 1, wherein the preparation method of the radix scrophulariae extract comprises the following steps: according to the weight percentage of ethanol: figwort =7, using 90% ethanol of mass concentration as a solvent, heating and extracting figwort with ethanol for 2-3 times, merging ethanol extract, cooling and precipitating for layering, and taking supernatant to obtain the figwort extract.
6. The blackhead removing traditional Chinese medicine composition according to claim 1, which comprises the following components in percentage by weight: 1% of cyperus rotundus extract, 1% of divaricate saposhnikovia root extract, 0.8% of white paeony root extract, 1% of astragalus extract, 0.5% of radix scrophulariae extract, 1-2% of 1, 3-butanediol, 0.5-1% of glycerol, 0.1-0.2% of sodium hyaluronate, 0.1-0.2% of arginine, 0.1-0.2% of carbomer, 0.5-1% of panthenol, 0.3-0.5% of betaine, 0.1-0.15% of dipotassium glycyrrhizinate, 0.5-1% of preservative and the balance of water, wherein the balance is added to 100%.
7. The blackhead removing traditional Chinese medicine composition as claimed in claim 1, wherein the preservative is a mixture of p-hydroxyacetophenone and hexanediol.
8. The method for preparing the blackhead removing traditional Chinese medicine composition according to any one of claims 1 to 7, which is characterized by comprising the following steps of:
(1) Heating the water phase to 80-85 ℃, sequentially adding 1, 3-butanediol, glycerol, carbomer, dipotassium glycyrrhizinate and sodium hyaluronate in the process of heating, and emulsifying and homogenizing for 90s when adding one component each;
(2) Cooling to 40-45 ℃, and sequentially adding panthenol, betaine, p-hydroxyacetophenone, cyperus rotundus extract, radix sileris extract, radix paeoniae alba extract, astragalus extract and figwort root extract;
(3) Adding arginine, and adjusting the pH value to 5.5-6.0 to obtain the blackhead removing traditional Chinese medicine composition.
9. The use of the blackhead removing traditional Chinese medicine composition as claimed in any one of claims 1 to 7 in a skin external cosmetic.
10. The use according to claim 9, wherein the cosmetic skin preparation comprises a serum, a cream, a lotion, a gel.
CN202210779861.9A 2022-07-04 2022-07-04 Blackhead-removing traditional Chinese medicine composition and application thereof Pending CN115487126A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106798693A (en) * 2017-02-14 2017-06-06 石家庄市中医院 A kind of Chinese medicine Face-protecting mask
CN110693780A (en) * 2019-10-31 2020-01-17 广东密尚生物科技有限公司 Skin nourishing composition and application thereof, and skin nourishing mask liquid
US20210093724A1 (en) * 2019-09-30 2021-04-01 Concept Matrix Solutions Topical anti-acne composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106798693A (en) * 2017-02-14 2017-06-06 石家庄市中医院 A kind of Chinese medicine Face-protecting mask
US20210093724A1 (en) * 2019-09-30 2021-04-01 Concept Matrix Solutions Topical anti-acne composition
CN110693780A (en) * 2019-10-31 2020-01-17 广东密尚生物科技有限公司 Skin nourishing composition and application thereof, and skin nourishing mask liquid

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