CN115461064A - 针对移植物抗宿主病的预防或治疗用组合物 - Google Patents

针对移植物抗宿主病的预防或治疗用组合物 Download PDF

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Publication number
CN115461064A
CN115461064A CN202080082543.6A CN202080082543A CN115461064A CN 115461064 A CN115461064 A CN 115461064A CN 202080082543 A CN202080082543 A CN 202080082543A CN 115461064 A CN115461064 A CN 115461064A
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China
Prior art keywords
dna
bacteroides
bacteria
unclassified
genus
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Pending
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CN202080082543.6A
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English (en)
Chinese (zh)
Inventor
垣花和彦
稻本恭子
本田贤也
竹下梢
切通优子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keio School
Tokyo Metropolitan Hospital Institution A Local Independent Administrative Legal Entity
JSR Corp
Original Assignee
Keio School
Floating Kyoto
JSR Corp
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Application filed by Keio School, Floating Kyoto, JSR Corp filed Critical Keio School
Publication of CN115461064A publication Critical patent/CN115461064A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202080082543.6A 2019-11-26 2020-11-25 针对移植物抗宿主病的预防或治疗用组合物 Pending CN115461064A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019213436 2019-11-26
JP2019-213436 2019-11-26
PCT/JP2020/043883 WO2021106952A1 (ja) 2019-11-26 2020-11-25 移植片対宿主病に対する予防又は治療用組成物

Publications (1)

Publication Number Publication Date
CN115461064A true CN115461064A (zh) 2022-12-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080082543.6A Pending CN115461064A (zh) 2019-11-26 2020-11-25 针对移植物抗宿主病的预防或治疗用组合物

Country Status (5)

Country Link
US (2) US20230024068A1 (https=)
EP (1) EP4085916A4 (https=)
JP (1) JPWO2021106952A1 (https=)
CN (1) CN115461064A (https=)
WO (1) WO2021106952A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118987051A (zh) * 2024-09-13 2024-11-22 南方医科大学南方医院 粪副拟杆菌在制备治疗移植物抗宿主病药物中的应用
CN120305292A (zh) * 2024-09-13 2025-07-15 南方医科大学南方医院 粪副拟杆菌在制备分离移植物抗白血病效应与移植物抗宿主病药物中的应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7783588B2 (ja) * 2021-07-21 2025-12-10 国立大学法人東海国立大学機構 腸内細菌叢に占めるコリンセラ属の情報を提供する方法、当該情報を用いたｃｏｖｉｄ－１９重症化予測方法およびサイトカインストーム重症化予測方法
US20240415900A1 (en) * 2021-10-20 2024-12-19 City Of Hope Clostridium butyricum compositions and methods of using the same
WO2025104216A1 (en) * 2023-11-15 2025-05-22 Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Bacteriophage compositions
JP2025174745A (ja) * 2024-05-17 2025-11-28 株式会社バイオパレット 人工腸内細菌叢の製造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160235792A1 (en) * 2014-11-25 2016-08-18 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
US20170258854A1 (en) * 2014-11-25 2017-09-14 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61282440A (ja) 1985-06-07 1986-12-12 マルチ−テツクス　プロダクツ　コ−ポレ−シヨン 複合糸製品
PH12013500224A1 (en) 2010-08-04 2013-04-08 Borody Thomas J Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
CA2896795A1 (en) 2012-11-26 2014-05-30 Thomas Julius Borody Compositions for the restoration of a fecal microbiota and methods for making and using them
US11167018B2 (en) * 2016-12-23 2021-11-09 Keio University Compositions and methods for the induction of CD8+ T-cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160235792A1 (en) * 2014-11-25 2016-08-18 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
US20170258854A1 (en) * 2014-11-25 2017-09-14 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
CN107249609A (zh) * 2014-11-25 2017-10-13 纪念斯隆-凯特琳癌症中心 肠道微生物群和gvhd
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SATOSHI KAITO等: "Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease", 《BLOOD ADV.》, vol. 2, no. 22, 27 November 2018 (2018-11-27), pages 3097 - 3101 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118987051A (zh) * 2024-09-13 2024-11-22 南方医科大学南方医院 粪副拟杆菌在制备治疗移植物抗宿主病药物中的应用
CN120305292A (zh) * 2024-09-13 2025-07-15 南方医科大学南方医院 粪副拟杆菌在制备分离移植物抗白血病效应与移植物抗宿主病药物中的应用
CN120531768A (zh) * 2024-09-13 2025-08-26 南方医科大学南方医院 粪副拟杆菌在制备治疗移植物抗宿主病药物中的应用

Also Published As

Publication number Publication date
US20250281549A1 (en) 2025-09-11
WO2021106952A1 (ja) 2021-06-03
JPWO2021106952A1 (https=) 2021-06-03
EP4085916A4 (en) 2024-03-27
EP4085916A1 (en) 2022-11-09
US20230024068A1 (en) 2023-01-26

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Applicant after: Tokyo Metropolitan Hospital Institution, a local independent administrative legal entity

Applicant after: Keio School

Applicant after: JSR Corp.

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Applicant before: Dong Jingdu

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Applicant before: JSR Corp.

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Application publication date: 20221209

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