CN115444909A - Composition for improving immunity and preparation method thereof - Google Patents

Composition for improving immunity and preparation method thereof Download PDF

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Publication number
CN115444909A
CN115444909A CN202211122195.8A CN202211122195A CN115444909A CN 115444909 A CN115444909 A CN 115444909A CN 202211122195 A CN202211122195 A CN 202211122195A CN 115444909 A CN115444909 A CN 115444909A
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parts
composition
deionized water
pregelatinized starch
immunity
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Inventor
陆继臣
吴淑霞
张玉凤
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Shandong Chuangshi Bioengineering Co ltd
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Shandong Chuangshi Bioengineering Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
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  • Botany (AREA)
  • Biotechnology (AREA)
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  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention provides a composition for improving immunity and a preparation method thereof, and relates to the technical field of health care products. The composition for improving immunity and the preparation method thereof comprise the following raw materials in parts by mass: seleno-carrageenan: 0.1-0.5 part, 10-30 parts of coix seed extract, 15-40 parts of dandelion extract, 5-20 parts of vitamin E powder, 10-30 parts of pregelatinized starch and 40-50 parts of deionized water, and comprises the following preparation steps: s1: the deionized water was divided into three portions, and one portion was mixed with pregelatinized starch to obtain a pregelatinized starch paste. By using simple health-care medicine collocation, useless additives are saved, the curative effect of the health-care product can be ensured, and the use of the types of the health-care medicine can be reduced, so that the medicine effect can be better absorbed by the human body, and the damage of the health-care medicine to the human body is reduced.

Description

Composition for improving immunity and preparation method thereof
Technical Field
The invention relates to the technical field of health care products, in particular to a composition for improving immunity and a preparation method thereof.
Background
The immunity is a defense mechanism of a human body, and the human body recognizes and eliminates any foreign matters (viruses, bacteria and the like) invaded from the outside; the capacity of treating aged, injured, dead and denatured self cells and recognizing and treating mutant cells and virus-infected cells in a human body, modern immunology considers that the immunity is a physiological reaction for recognizing and eliminating 'isohexia' of the human body, and the immunity of the human body is different according to the constitution of each person, so that the immunity of some people is high, and the immunity of some people is low.
At present, with the increase of working pressure of people, the time of rest exercise is correspondingly reduced, so that the immunity of people is reduced, and the health care product for improving the immunity of human bodies is born.
When the applicant applies the invention, through retrieval, chinese patents are found to disclose 'a pharmaceutical composition for improving immunity and a preparation method thereof', the application number of the pharmaceutical composition is '201110023849.7', 'a soft capsule for improving immunity', the application number of the soft capsule is '201410755392.2', 'a traditional Chinese medicine extract composition for improving immunity, a preparation method thereof and an application thereof in preparing a medicine for improving immunity', the application number of the soft capsule is '201410755392.2', 'a composition for improving immunity and a preparation method and an application thereof', and the application number of the composition is '201710103722.3'.
The above-mentioned Chinese patents related to health products are searched, wherein the health products adopt too many kinds of health drugs and cannot be well absorbed by human bodies, and although the immunity of the human bodies can be improved to a certain extent, the health products can cause certain damage to the human bodies after long-term use.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a composition for improving immunity and a preparation method thereof, and solves the problems that the existing health-care products adopt too many kinds of health-care medicines, can not be well absorbed by human bodies, can improve the immunity of the human bodies to a certain extent, but can cause certain damage to the human bodies after long-time use.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: the composition for improving immunity comprises the following raw materials in parts by mass: seleno carrageenan: 0.1-0.5 part of coix seed extract, 10-30 parts of coix seed extract, 15-40 parts of dandelion extract, 5-20 parts of vitamin E powder, 10-30 parts of pregelatinized starch and 40-50 parts of deionized water.
Preferably, the feed comprises the following raw materials in parts by mass: seleno-carrageenan: 0.3 part, 15 parts of coix seed extract, 25 parts of dandelion extract, 13 parts of vitamin E powder, 22 parts of pregelatinized starch and 45 parts of deionized water.
Preferably, the method comprises the following preparation steps:
s1: dividing deionized water into three parts, and mixing one part of the deionized water with pregelatinized starch to obtain pregelatinized starch paste;
s2: averagely dividing the pregelatinized starch paste into four parts, respectively mixing with the selenocarrageenan, the coix seed extract, the dandelion extract and the vitamin E powder, and successively adding deionized water for stirring to obtain four parts of pasty mixture;
s3: mixing the four parts of the pasty mixture together, and adding deionized water to fully mix the four parts of the pasty mixture together to obtain a final composition;
s4: the final composition is placed in a mold and dried to provide pellets of the composition.
Preferably, the mass ratio of the three parts of deionized water in the S1 is 5: 3: 2, and the deionized water is used sequentially from large to small according to the mass ratio.
Preferably, the stirring time in S2 is 30min, and the stirring speed is 180r/min.
Preferably, the final composition of the composition in S3 is in a fluid state.
(III) advantageous effects
The invention provides a composition for improving immunity and a preparation method thereof. The method has the following beneficial effects:
by using simple health-care medicine collocation, useless additives are saved, the curative effect of the health-care product can be ensured, and the use of the types of the health-care medicine can be reduced, so that the medicine effect can be better absorbed by the human body, and the damage of the health-care medicine to the human body is reduced.
Detailed Description
Technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The first embodiment is as follows:
the embodiment of the invention provides a composition for improving immunity, which comprises the following raw materials in parts by mass: seleno carrageenan: 0.1-0.5 part, 10-30 parts of coix seed extract, 15-40 parts of dandelion extract, 5-20 parts of vitamin E powder, 10-30 parts of pregelatinized starch and 40-50 parts of deionized water.
The feed comprises the following raw materials in parts by mass: seleno carrageenan: 0.3 part, 15 parts of coix seed extract, 25 parts of dandelion extract, 13 parts of vitamin E powder, 22 parts of pregelatinized starch and 45 parts of deionized water.
A preparation method of a composition for improving immunity comprises the following preparation steps:
s1: dividing deionized water into three parts, and mixing one part of the deionized water with pregelatinized starch to obtain pregelatinized starch paste;
s2: averagely dividing the pregelatinized starch paste into four parts, respectively mixing with the selenocarrageenan, the coix seed extract, the dandelion extract and the vitamin E powder, and successively adding deionized water for stirring to obtain four parts of pasty mixture;
s3: mixing the four parts of the pasty mixture together, and adding deionized water to fully mix the four parts of the pasty mixture together to obtain a final composition;
s4: the final composition is placed in a mold and dried to provide pellets of the composition.
The mass ratio of the three parts of deionized water in the S1 is 5: 3: 2, and the deionized water is used in sequence from large to small according to the mass ratio.
The stirring time in the S2 is 30min, and the stirring speed is 180r/min.
The state of the final composition of the composition in S3 is a fluid state.
Example two:
the embodiment of the invention provides a composition for improving immunity, which comprises the following raw materials in parts by mass: the Grifola frondosa extract: 5-50 parts of mushroom extract, 8-20 parts of mushroom extract, 8-30 parts of astragalus extract and 40-50 parts of deionized water.
The feed comprises the following raw materials in parts by mass: grifola frondosa extract: 30 parts of mushroom extract, 13 parts of astragalus extract and 46 parts of deionized water.
A method for preparing a composition for enhancing immunity comprises the following steps:
s1: mixing deionized water with Grifola frondosa extract, lentinus edodes extract and radix astragali extract, and stirring to obtain paste composition;
s2: placing the paste composition in a mold, and drying to obtain composition pill.
Example three:
randomly selecting 200 volunteers with low immunity, wherein the volunteers are 28-55 years old and all have the symptoms of physical weakness, malnutrition, listlessness, fatigue, weakness, appetite reduction, sleep disorder, susceptibility to diseases, difficulty in recovery, repeated infection and the like, randomly distributing the volunteers into 2 groups, distributing the pills prepared in the first embodiment into one group, and distributing the pills prepared in the second embodiment into two groups;
the dosage of the health care product for each group of volunteers is 1 granule per time, 30 days are a treatment course, and after 90 days, the investigation result is as follows:
Figure BDA0003847632670000041
Figure BDA0003847632670000051
although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A composition for enhancing immunity, comprising: the composite material comprises the following raw materials in parts by mass: seleno carrageenan: 0.1-0.5 part, 10-30 parts of coix seed extract, 15-40 parts of dandelion extract, 5-20 parts of vitamin E powder, 10-30 parts of pregelatinized starch and 40-50 parts of deionized water.
2. The composition for enhancing immunity of claim 1, wherein: the composite material comprises the following raw materials in parts by mass: seleno carrageenan: 0.3 part, 15 parts of coix seed extract, 25 parts of dandelion extract, 13 parts of vitamin E powder, 22 parts of pregelatinized starch and 45 parts of deionized water.
3. A method of preparing an immunity enhancing composition as claimed in any one of claims 1 to 2, wherein: the preparation method comprises the following preparation steps:
s1: dividing deionized water into three parts, and mixing one part of the deionized water with pregelatinized starch to obtain pregelatinized starch paste;
s2: averagely dividing the pregelatinized starch paste into four parts, respectively mixing with the selenocarrageenan, the coix seed extract, the dandelion extract and the vitamin E powder, and successively adding deionized water for stirring to obtain four parts of pasty mixture;
s3: mixing the four paste mixtures together and adding deionized water to mix them thoroughly to obtain the final composition;
s4: the final composition is placed in a mold and dried to provide pellets of the composition.
4. The method for preparing the composition for improving immunity according to claim 3, wherein the composition comprises the following components: the mass ratio of the three parts of deionized water in the S1 is 5: 3: 2, and the deionized water is used in sequence from large to small according to the mass ratio.
5. The method for preparing the composition for improving immunity according to claim 3, wherein the composition comprises the following components: the stirring time in the S2 is 30min, and the stirring speed is 180r/min.
6. The method of claim 3, wherein the step of preparing the composition for enhancing immunity comprises: the state of the final composition of the composition in S3 is a fluid state.
CN202211122195.8A 2022-09-15 2022-09-15 Composition for improving immunity and preparation method thereof Pending CN115444909A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050084530A1 (en) * 1999-12-01 2005-04-21 Natco Pharma Limited Rapid acting freeze dried oral pharmaceutical composition for treating migraine
CN103494203A (en) * 2013-10-18 2014-01-08 济南老来寿生物股份有限公司 Healthcare food with immunity boosting function
CN106310023A (en) * 2016-11-10 2017-01-11 林树芳 Drug for treating small cell lung cancer, and preparation method and application thereof
CN113171426A (en) * 2021-05-10 2021-07-27 养淬堂(北京)生物技术有限公司 Composition for improving immunity and preparation method and application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050084530A1 (en) * 1999-12-01 2005-04-21 Natco Pharma Limited Rapid acting freeze dried oral pharmaceutical composition for treating migraine
CN103494203A (en) * 2013-10-18 2014-01-08 济南老来寿生物股份有限公司 Healthcare food with immunity boosting function
CN106310023A (en) * 2016-11-10 2017-01-11 林树芳 Drug for treating small cell lung cancer, and preparation method and application thereof
CN113171426A (en) * 2021-05-10 2021-07-27 养淬堂(北京)生物技术有限公司 Composition for improving immunity and preparation method and application thereof

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