CN115414424B - Phyllanthus emblica spray for preventing and treating alopecia and promoting hair growth and preparation method thereof - Google Patents
Phyllanthus emblica spray for preventing and treating alopecia and promoting hair growth and preparation method thereof Download PDFInfo
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- CN115414424B CN115414424B CN202210395223.7A CN202210395223A CN115414424B CN 115414424 B CN115414424 B CN 115414424B CN 202210395223 A CN202210395223 A CN 202210395223A CN 115414424 B CN115414424 B CN 115414424B
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
The invention discloses an emblic leafflower fruit spray for preventing and curing alopecia and growing hair and a preparation method thereof, relating to the technical field of traditional Chinese medicines, and the technical scheme is as follows: the phyllanthus emblica spray is prepared from solute and solvent according to the proportion of 1:4; the solute comprises phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli, and the ratio of phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli is 5:2:1:0.5:0.25; the solvent is brewed white spirit with the alcohol content of more than 45 degrees. The phyllanthus emblica spray has the functions of preventing and treating alopecia, poor hair quality, loose hair roots, sparse hair, greasy hair, subjective itching, dandruff and the like, and has the function of hair care.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to an emblic leafflower fruit spray for preventing and treating alopecia and fertility and a preparation method thereof.
Background
Alopecia is mainly caused by unstable hair roots due to the quantity of bacon (badkan), blood (khrag), red (mkhrispa) and yellow water (chuser) which are the components of the head, and has alopecia symptoms of alopecia areata, unstable hair roots, poor hair quality, sparse hair, greasy hair, subjective itching, dandruff and other complications. At present, the cause of alopecia is not clear clinically, but Tibetan medicine considers that people are in a tired and staying up state for a long time along with the acceleration of life rhythm and pressure, and part of people frequently drink wine for relieving reasons such as pressure or bad life habits, and the other part of people are in a dysphoria with excessive pressure, so that the mood is unstable and the mood is difficult to become the cause of alopecia.
The rapid development of modern medicine and health market develops various hair-nourishing, hair-nourishing or hair-loss-preventing medicines and hair-washing products, and even Tibetan medicines develop a lot of dropoff and hair-nourishing products, but really have obvious effects on hair loss and hair-nourishing. The Western medicine has the functions of treating alopecia, including medicine treatment, nanometer technology, physical treatment, surgical operation, etc. The preferred medicines for treating the alopecia by western medicines are minoxidil and finasteride tablets, and the effects and side effects are obvious, but the influence of the alopecia is not completely solved at present or the treatment requirement is still difficult to meet. Compared with western medicines, the Chinese herbal medicine has the advantages of remarkable medicine effect, high compliance, less side effect, wide activity spectrum, low price, wide application range and the like.
Therefore, the invention aims to provide an emblic leafflower fruit spray for preventing and curing alopecia and growing hair and a preparation method thereof so as to solve the problems.
Disclosure of Invention
The invention aims to solve the problems and provide the emblic leafflower fruit spray for preventing and curing alopecia and growing hair and the preparation method thereof.
The technical aim of the invention is realized by the following technical scheme: an emblic leafflower fruit spray for preventing and curing alopecia and fertility hair is prepared from solute and solvent according to the proportion of 1:4; the solute comprises phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli, and the ratio of phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli is 5:2:1:0.5:0.25; the solvent is brewed white spirit with the alcohol content of more than 45 degrees.
In the scheme, according to the cause treatment and symptom improvement conditions of alopecia and hair growth and the efficacy of medicinal materials, the phyllanthus emblica in the formula of the phyllanthus emblica spray is a main medicine, has more efficacy, and has the effects of growing hair, cleaning hair root oily substances and deteriorating blood; the fructus Terminaliae Billericae has effects of long hair, drying head and hair root, deteriorating blood and yellow water, and has less effects than fructus Phyllanthi; the myrobalan is called as the monarch of Tibetan medicinal materials, and has the main effect of regulating metabolism, so that the medicine is less; the multi-pulse cat milk has only the treatment effects of dry yellow water and spoiled blood, so that the cat milk is relatively less; the pricklyash peel has the effects of sterilizing, relieving itching and opening pores, but the main formula is that pores are opened, and the efficacy is the least. The medicine has relatively large proportion of medicines with more curative effect and efficacy, less single efficacy and minimum medicine with efficacy guiding effect.
In addition, the brewing white spirit is used as a solvent, and has the following advantages: 1. the effective components in the medicinal materials can be conveniently extracted, and the effect is good; 2. can replace preservative and is safer; 3. the brewed white wine has higher nutrition than other solvents, and can supplement nutrition for the hair roots; 4. the brewed white spirit is easy to volatilize and is more convenient to use than the oily solvent; 5. has proper disinfection effect.
Further, the phyllanthus emblica, the Terminalia bellerica and the multi-vein cat milk are all concentrated paste.
Further, the myrobalan is obtained from the fruit of Tibet olive.
The invention also provides a preparation method of the emblic leafflower fruit spray for preventing and treating alopecia and fertility, which comprises the following steps:
s1, preparing paste:
a. cleaning the plaster material for 3 times;
b. soaking in warm water for 3 days, wherein the warm water is covered with 1-2cm, if the water is absorbed by the medicinal material at the 2 nd day until the water level is reduced to the medicinal material, continuously adding water until the medicinal material is covered, stirring for 2 times, and then performing filtering and liquid separation operation for 3 times;
c. filtering the filtrate with four layers of medical gauze again, heating and concentrating until the water is evaporated;
d. drying the heated paste for 3-7 days;
s2, pharmacy:
weighing the medicinal materials according to a proportion, placing the medicinal materials into a high-quality plastic barrel or a stainless steel barrel, adding brewed white spirit, stirring for 1 time, sealing and storing, stirring for 1 time on the 7 th day, stirring for 1 time on the 14 th day, diluting with filtered water to 45 degrees of alcoholic strength on the 21 st day, and stirring for one time; wherein, after each stirring, sealing and storing, filtering with 16 layers of medical gauze on the 24 th day, passing through a 200-mesh sieve, clarifying the filtrate, separating precipitate, and finally enabling the ratio of solute to solvent to reach 1:4, preparing the emblic leafflower fruit spray solution.
S3, packaging: and (5) bottling 90ml of liquid in each bottle of the prepared phyllanthus emblica spray solution to obtain the phyllanthus emblica spray.
Further, the ointment medicinal materials in the step S1 are phyllanthus emblica, terminalia bellerica and multi-vein cat milk.
Further, the medicinal materials in the step S2 comprise ointment, pepper and myrobalan after the ointment is prepared in the step S1.
Mechanism of action:
tibetan medicine considers that the direct cause of alopecia is that yellow water, blood volume or deterioration of body components affect the firmness of hair roots and alopecia, and the fusion head of the yellow water and the deteriorated blood generates greasiness, and the yellow water lesions have clinical manifestations of itching. The formulation of the invention has the functions of improving the hair root insecurity and the yellowing water and metamorphic blood of the dry head by aiming at the etiology treatment of phyllanthus emblica, terminalia chebula and multi-pulse cat milk, improving the head composition disorder by the fructus zandrae, regulating metabolism, treating the hair to absorb nutrition and dandruff, the phyllanthus emblica and the Terminalia bellerica fruit promote hair growth, the pepper disinfects and relieves itching, and meanwhile, the pore-opening medicines are opened to guide the hair cortex and the hair root, after the etiology of the hair root is removed, the hair cortex can normally provide nutrition for the hair, the hair quality can be improved, the hair can be promoted to grow normally, and the defect of the hair root can be changed.
In addition, the phyllanthus emblica has the effects of cooling blood and growing hair, and has the effects of growing hair and cleaning hair root oily substances and spoiled blood; the fructus Terminaliae Billericae has effects of clearing heat and detoxicating, drying yellow water, and growing hair, and can be used for growing hair, drying head and hair root, and deteriorating blood and yellow water; the medicine of the formula of the invention is prepared from one of five kinds of chebula, namely Tibetan olive, which is called the monarch of Tibetan medicine, and has the function of regulating metabolism, wherein the Tibetan olive is used for clinical treatment of brain diseases and difficult and complicated diseases; the multi-pulse cat milk has the effects of treating dry yellow water and metamorphic blood.
In summary, the invention has the following beneficial effects:
1. the emblic leafflower fruit spray has the functions of preventing and treating alopecia, poor hair quality, loose hair roots, greasy hair, subjective itching and dandruff, and has the function of hair care;
2. the phyllanthus emblica spray is in a liquid state, active ingredients of raw materials of the medicament are easier to dissolve completely in the preparation process, the prepared medicament is easier to absorb, and the use is convenient;
3. in the preparation method of the emblic leafflower fruit spray, the ointment preparation medicinal materials are concentrated into ointment and then are prepared, so that the prepared emblic leafflower fruit spray has better medicinal effect.
Drawings
FIG. 1 is a graph showing the therapeutic effect of Tibetan medicine according to the embodiment of the present invention;
FIG. 2 is a line graph of improvement of individual symptoms in an embodiment of the present invention;
FIG. 3 is a bar graph of a fertility status in an embodiment of the invention;
FIG. 4 is a graph showing the improvement of symptoms per course of treatment in the examples of the present invention;
fig. 5 is a graph of coefficient of variation data for symptoms per session in an embodiment of the invention.
Detailed Description
In order that those skilled in the art will better understand the present invention, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings, wherein it is to be understood that the illustrated embodiments are merely exemplary of some, but not all, of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, shall fall within the scope of the present invention.
It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other. The present invention will be described in detail with reference to examples.
Examples:
an emblic leafflower fruit spray for preventing and curing alopecia and fertility is prepared from solute (kg) and solvent (L) according to the proportion of 1:4; the solute comprises phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli, wherein the fructus Chebulae is obtained from fructus Chebulae, and the ratio of phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli is 5:2:1:0.5:0.25; the solvent is brewed white spirit with the alcohol content of more than 45 degrees.
Wherein, the phyllanthus emblica, the Terminalia bellerica and the multi-vein cat milk are all concentrated paste.
A preparation method of phyllanthus emblica spray for preventing and treating alopecia and fertility hair comprises the following steps:
s1, preparing paste:
a. cleaning the plaster material for 3 times;
b. soaking in warm water for 3 days, wherein the warm water is covered with 1-2cm, if the water is absorbed by the medicinal material at the 2 nd day until the water level is reduced to the medicinal material, continuously adding water until the medicinal material is covered, stirring for 2 times, and then performing filtering and liquid separation operation for 3 times;
c. filtering the filtrate with four layers of medical gauze again, heating and concentrating until the water is evaporated;
d. drying the heated paste for 3-7 days;
s2, pharmacy:
weighing the medicinal materials according to a proportion, placing the medicinal materials into a high-quality plastic barrel or a stainless steel barrel, adding brewed white spirit, stirring for 1 time, sealing and storing, stirring for 1 time on the 7 th day, stirring for 1 time on the 14 th day, diluting with filtered water to 45 degrees of alcoholic strength on the 21 st day, and stirring for one time; wherein, after each stirring, sealing and storing, filtering with 16 layers of medical gauze on the 24 th day, passing through a 200-mesh sieve, clarifying the filtrate, separating precipitate, and finally enabling the ratio of solute to solvent to reach 1:4, preparing the emblic leafflower fruit spray solution.
S3, packaging: and (5) bottling 90ml of liquid in each bottle of the prepared phyllanthus emblica spray solution to obtain the phyllanthus emblica spray.
Wherein the ointment medicinal materials in the step S1 are phyllanthus emblica, terminalia bellerica and multi-pulse cat milk.
Wherein the medicinal materials in the step S2 comprise the medicinal materials, the pepper and the myrobalan after the ointment preparation in the step S1.
In this embodiment, among the five kinds of chebula fruit called in Tibetan medicine, the configuration effect is better by using the Tibetan olive. The application method of the emblic leafflower fruit spray comprises the following steps: for external use, 2-3 times a day; spraying hair roots, massaging the head 15 minutes after the scalp is moistened to enable the hair roots to be fully absorbed, and cleaning and erasing after 30 minutes; it should be used with cautions for people with alcohol allergy.
The following is the observation of clinical efficacy of the emblic leafflower fruit spray:
1. data and methods:
1.1 analysis of the composition of the commonly used alopecia formulations
The Tibetan medicine, the Chinese and western medicine and the natural medicine which are clinically applied to treating alopecia have different characteristics, the common natural plant medicine for treating alopecia is ginger, biota orientalis, ginseng, polygonum multiflorum, turmeric, fennel, pumpkin, red cloves and the like, and the single medicine for treating alopecia with high frequency in the Tibetan medicine literature records is phyllanthus emblica, peach kernel, caltrop, terminalia bella, sesame, honey, butter, lard, milk, white spirit and the like in sequence. The Tibetan medicine treatment is based on the principle that hair loss is improved by treating the etiology of yellow water and the like of hairy roots, the hair loss is generated by improving the symptom of the hair loss, the traditional Chinese medicine treatment is based on the clinical treatment of clearing heat and removing dampness, cooling blood and dispelling wind and moistening dryness, nourishing liver and kidney, and the western medicine treatment is based on blood circulation and the like, so that the selected medicines are different.
1.2 sources of case data
The Tibetan medicine emblic spray is developed in Tibetan autonomous area Tibetan medicine hospital from 9 in 2021 to 2 in 2022 in 10 days, and the clinical curative effect observation study for preventing and treating seborrheic alopecia is carried out to collect the report form data of the case of patients suffering from seborrheic alopecia, and the effective cases are 63.
2. Method of
2.1 inclusion and exclusion criteria
2.1.1 inclusion criteria
(1) The patients who meet the Western diagnosis standard lose more than 100 hair loss per day, and have the following 1-2 symptoms: thinning hair, lightening hair, thinning hair, excessive grease, subjective itching, dandruff and the like; (2) Meets the Tibetan diagnostic standard, and determines the symptoms according to theoretical explanation of Tibetan classical huge 'four medical classics', and the like and the combination of clinical expert demonstration: seborrheic alopecia, poor hair quality, loose hair roots, sparse hair, greasy hair, subjective itching and dandruff, and can be diagnosed by adding more than 2 to 3 symptoms of the seborrheic alopecia. (3) the age is 18-45 years; (4) sign informed consent.
2.1.2 exclusion criteria
(1) Patients with alopecia; (2) patients with alopecia areata; (3) hair planting crowd; (4) physical hair loss; (5) chemical hair loss; (6) infectious alopecia; (7) symptomatic hair loss; (8) congenital alopecia; (9) alcohol allergic constitution; (10) pregnant, ready-to-gestate or lactating women; (11) those with history of drug allergy or allergic constitution; (12) psychotic patients; (13) Suspected or confirmed history of alcohol, drug abuse, or other lesions or conditions that reduce the likelihood of or complicate group entry, as judged by the study, such as conditions that are prone to missed visits, e.g., frequent changes in working environment, unstable living environment, etc.; (14) patients who were taking part in other clinical trials within 3 months.
2.2 clinical study methods
The patients with seborrheic alopecia are recruited to carry out the prospective study of the front and back contrast, and the patients with seborrheic alopecia are first treated, and 7 symptoms such as seborrheic alopecia, hair deterioration, unstable hair root, sparse hair, greasy hair, subjective pruritus, dandruff and the like are not integrated into 0 score, are not obvious into 2 scores, are obvious into 4 scores and are serious into 6 scores, and are administrated through the head for 2 to 3 times in 1 day. Spraying hair roots, massaging the head 15 minutes after the scalp is moistened to enable the hair roots to be fully absorbed, and cleaning and erasing after 30 minutes. The administration period is 1 course of treatment for 4 weeks + -3 days, and total is 3 courses of treatment. Each treatment course is subjected to follow-up scoring and picture collection of each symptom, each follow-up period is subjected to a Visual analogue scale visual simulation method (0 is divided into no alopecia, 1-3 is divided into 0-50 daily alopecia, 4-6 is divided into 51-100 daily alopecia, 7-10 is divided into daily alopecia exceeding 100), comparison of score changes before and after treatment of the maximum value of the NRS score of hair growing (0 is remarkable, 1-3 is obvious, 4-6 is not obvious, 7-9 is almost no, 10 is not obvious), other symptoms such as unstable hair roots, sparse hair, greasy hair, subjective pruritus, dandruff and the like score improvement conditions of the hair growing in 0-10 partition (0 is remarkable, 1-3 is obvious, 4-6 is not obvious, 7-9 is almost no, 10 is not obvious.)
2.3 statistical methods
2.3.1 Tibetan medicine symptom curative effect determination criterion
Calculated according to nimodipine method: the efficacy index (n) = [ (total integral before treatment-total integral after treatment)/(total integral before treatment ] ×100% (without hair-growing integral). The standard is formulated by referring to the guidelines of the national health Committee for health of the people's republic of China, and the recovery is realized by: symptoms and signs disappear or disappear basically, and the integral reduction is more than or equal to 95%; the effect is shown: the clinical symptoms and signs are obviously improved, and the integral is reduced by more than or equal to 70 percent and less than 95 percent; the method is effective: the clinical symptoms and signs are all improved, and the integral is reduced by more than or equal to 30 percent and less than 70 percent; invalidation: the clinical symptoms and signs are not obviously improved or even aggravated, and the integral is reduced by less than 30 percent.
2.3.2 Single symptom efficacy assessment criteria
According to the clinical symptom improvement condition, the score after single symptom treatment is changed to 0 score, the score after treatment is changed to 1-3, and the score after treatment is not changed to 4-10. The score of hair growth was assumed to be 10 points before treatment, significantly 0 points after treatment, significantly 1-3 points, and not changed to 4-10 points. Those without single symptoms have no score.
2.3.3 statistical analysis
All data are recorded in Microsoft Office Excel 2016 and are uniformly arranged, R64 statistical analysis software is imported to conduct data management and statistical analysis, and technical data adopt chi-square (chi-square) 2 ) The statistical data in the case report table are the age, sex, alopecia, hair growth, hair quality deterioration, hair root weakness, hair sparseness, hair greasiness, subjective pruritus, dandruff and other symptoms of the subject, and the improvement condition scoring and the Tibetan medicine comprehensive symptom curative effect judgment of each symptom during the treatment follow-up, and the picture is collected.
3. Safety evaluation
3.1 ethical examination
The study is examined by the ethical committee of Tibetan autonomous region Tibetan medicine, and accords with the ethical principles of the national Wei Jian Committee (the method of ethical examination for biomedical research involving human (2016), the pharmaceutical clinical trial quality management Specification (GCP) 2020, the medical instrument clinical trial quality management Specification (2016), the Chinese medical clinical research ethical examination management Specification (2010), the Hull octyl statement and the guidelines for ethical examination for pharmaceutical clinical trial (CFDA, 2010), and the acceptance number/the part number:
QZYY2021-IRBSL-12/QZYY2021-IRBPJ-12, approved File clinical study protocol version number/date: 202101001/20210720 subject informed consent version number/date: 202101001/20210720.
3.2 adverse reactions
Adverse events: recording at any time in detail, wherein no abnormal physical manifestation occurs in the research process.
Results 4 results
4.1 basic case
As a result of the study, the number of men and women was greater than that of the patients, P > 0.05, and there was no statistical significance for the age distribution, whereas the number of patients with age distribution between 26 and 35 years was the largest, the number between 36 and 45 years was relatively small, and the number between 18 and 25 years was the smallest, and P > 0.05 (see Table 1).
Table 1 sex, age base unit: example(s)
4.2 curative effect on Tibetan medicine symptoms
The comprehensive judgment of the curative effects of Tibetan medicine symptoms (Table 2) shows that the curative effects of 3 cases of the effective cases of the subjects are 4.8%, the effective effects of 36 cases are 57.1%, the effective effects of 21 cases are 33.3%, and the ineffective effects of 3 cases are 4.8%, and the scores of symptoms such as alopecia, hair quality deterioration, hair root weakness, hair thinning, hair greasiness, subjective pruritus and dandruff are improved. The significant effect and effectiveness are significant results (see fig. 1).
Table 2 Tibetan medicine syndrome curative effect determination unit: example(s)
4.3 improvement of the individual symptoms
The symptoms such as single symptom alopecia, poor hair quality, loose hair roots, sparse hair, greasy hair, subjective itching, dandruff and the like are all improved (table 3), and the disappearance and improvement of the symptoms are most obvious in 63 effective cases (see figure 2).
Table 3 unit of improvement of individual symptoms: EXAMPLE (%)
4.4 conditions for fertility
In 63 effective cases (Table 4) of the study, the number of the effective cases is shown to be 0, the number of the effective cases is obviously up to 65.1% in 41, the number of the effective cases is not changed into 22 cases, 34.9%, and the number of the effective cases is 4-10, so that the effective cases are calculated to be unchanged in hair growth (see figure 3).
Table 4 hair-growing symptom improvement unit: example(s)
4.5 mean value per treatment course
The single symptom score is analyzed to change from the first visit to the 3 rd visit by each visit data (table 5), the score of each symptom (hair-growing) at the 3 rd visit is about 1 minute, the score is improved from obvious and serious 4-6 minutes to 0 < to less than or equal to 3, the average score of the first visit of hair-growing is assumed to be 10 minutes, and the average value is reduced to 3.7 minutes at the 3 rd visit, which shows that the effect is achieved. The statistical significance before and after treatment was analyzed by R64 statistical software (p=0.0345 < 0.05).
Table 5 unit of symptom improvement per treatment course:
the symptoms were significantly changed by comparing the first visit, second visit, third visit, and integration from front to back (see fig. 4).
By coefficient of variation formulaAfter the data are processed, as shown in fig. 5, each symptom is improved, and the effects of improving the symptoms of alopecia, greasy hair, subjective itching and dandruff are more remarkable.
4.5 Picture analysis of representative fertility cases
The first visit of 10 representative hair-growing cases in the study is compared with the third follow-up picture after 3 treatment courses, the first visit is scored by a vegetation coverage measuring method, the first visit is assumed to be the head hair-free percentage of 0 percent, the percentage scoring is carried out after three months (table 6), and the average hair-growing value of 10 subjects is calculated by R64 to reach 21.55 percent.
TABLE 6 analysis chart of hair growth acquisition pictures
Conclusion:
with more and more patients suffering from seborrheic alopecia, various germinants are developed on the market, and at least 122 classical proved formulas for preventing alopecia and developing are recorded in Tibetan medicine. The Tibetan medicine emblic leafflower fruit spray of the invention also has certain curative effect on preventing and curing alopecia and hair-growing. The comprehensive determination result of the curative effect of the Tibetan medicine symptoms shows that the curative effect of the Tibetan medicine symptoms in 63 cases of effective cases of the subjects is that the curative effect of the Tibetan medicine symptoms is cured by 3 cases and is 4.8%, the effective rate is 57.1% for 36 cases, the effective rate is 33.3% for 21 cases, the ineffective rate is 4.8% for 3 cases, and the effective rate are obvious. The symptoms are eliminated and improved most obviously in the improvement situations of single symptom alopecia, poor hair quality, loose hair roots, sparse hair, greasy hair, subjective pruritus, dandruff and the like. The average score of the first visit of the hair care is assumed to be 10 minutes, the average value is reduced to 3.7 minutes at the 3 rd follow-up visit, and 65.1 percent of the hair care occurrence is obvious, thus indicating the effect. The representative picture scores are collected by a biological vegetation coverage measurement method, the average breeding of the subjects is developed to 21.55%, and adverse reactions are not found in the research process. Three of the 63 additional cases (numbers 0118, 0119, 0140) fed back this drug also had a hair darkening effect, which could be further studied for patients with white hair. Therefore, the Tibetan medicine emblic leafflower fruit spray can be applied to clinically treating alopecia and hair growth, and can solve a certain amount of seborrheic alopecia patients.
The present embodiment is only for explanation of the present invention and is not to be construed as limiting the present invention, and modifications to the present embodiment, which may not creatively contribute to the present invention as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present invention.
Claims (1)
1. An emblic leafflower fruit spray for preventing and curing alopecia and fertility, which is characterized in that: the phyllanthus emblica spray is prepared from solute and solvent according to the proportion of 1:4; the solute is composed of phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli, and the ratio of phyllanthus emblica, fructus Terminaliae Billericae, fructus Chebulae, multi-pulse cat milk and fructus Zanthoxyli is 5:2:1:0.5:0.25; the solvent is brewed white spirit with the alcohol content of more than 45 degrees;
the preparation method of the emblic leafflower fruit spray for preventing and treating alopecia and fertility comprises the following steps:
s1, preparing paste:
a. cleaning the plaster material for 3 times;
b. soaking in warm water for 3 days, wherein the warm water is covered with 1-2cm, if the water is absorbed by the medicinal material at the 2 nd day until the water level is reduced to the medicinal material, continuously adding water until the medicinal material is covered, stirring for 2 times, and then performing filtering and liquid separation operation for 3 times;
c. filtering the filtrate with four layers of medical gauze again, heating and concentrating until the water is evaporated;
d. drying the heated paste for 3-7 days;
s2, pharmacy:
weighing the medicinal materials according to a certain proportion, placing the medicinal materials into a plastic bucket or a stainless steel bucket, adding brewed white spirit, stirring for 1 time, sealing and storing, stirring for 1 time on the 7 th day, stirring for 1 time on the 14 th day, adding filtered water to dilute to 45 degrees of alcoholic strength on the 21 st day, and stirring for one time; wherein, after each stirring, sealing and storing, filtering with 16 layers of medical gauze on the 24 th day, passing through a 200-mesh sieve, clarifying the filtrate, separating precipitate, and finally enabling the ratio of solute to solvent to reach 1:4, preparing phyllanthus emblica spray solution;
s3, packaging: the prepared phyllanthus emblica spray solution is bottled with 90ml of liquid to obtain phyllanthus emblica spray;
the phyllanthus emblica, the Terminalia bellerica and the multi-vein cat milk are all concentrated paste; the fructus Chebulae is obtained from fructus Chebulae; the ointment preparation medicinal materials in the step S1 are phyllanthus emblica, terminalia bellerica and multi-vein cat milk;
the medicinal materials in the step S2 comprise the ointment, the pepper and the myrobalan after the ointment is prepared in the step S1.
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258437A (en) * | 2010-05-28 | 2011-11-30 | 旦巴颜排 | Hair nourishing liquid |
| CN102697938A (en) * | 2012-06-29 | 2012-10-03 | 乌鲁木齐哈孜巴义生发技术研究所（有限公司） | Natural hair growth promoting liquid and preparation method thereof |
| CN102784216A (en) * | 2012-09-11 | 2012-11-21 | 久美彭措 | Traditional Tibetan medicine for treating alopecia |
| CN103041042A (en) * | 2013-01-25 | 2013-04-17 | 西藏福田藏医药研究开发有限公司 | Tibetan medicine composition and application of composition in anti-off hair products |
| CN107485707A (en) * | 2017-08-03 | 2017-12-19 | 文成当智 | A kind of Tibetan medicinal composition and its application |
| CN108576812A (en) * | 2018-04-27 | 2018-09-28 | 西藏藏医学院 | Composition with fat melting refreshing effect and its processing method |
| CN110101776A (en) * | 2019-06-25 | 2019-08-09 | 西藏圣雪生物科技有限公司 | A kind of Tibetan medicinal composition of hair-growing and anti-hair loss and preparation method thereof |
| CN215938774U (en) * | 2021-05-31 | 2022-03-04 | 西藏自治区藏医院(西藏自治区藏医药研究院) | Intelligent Tibetan medicine miscellaneous vessel Chong pot therapeutic instrument |
-
2022
- 2022-04-15 CN CN202210395223.7A patent/CN115414424B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258437A (en) * | 2010-05-28 | 2011-11-30 | 旦巴颜排 | Hair nourishing liquid |
| CN102697938A (en) * | 2012-06-29 | 2012-10-03 | 乌鲁木齐哈孜巴义生发技术研究所（有限公司） | Natural hair growth promoting liquid and preparation method thereof |
| CN102784216A (en) * | 2012-09-11 | 2012-11-21 | 久美彭措 | Traditional Tibetan medicine for treating alopecia |
| CN103041042A (en) * | 2013-01-25 | 2013-04-17 | 西藏福田藏医药研究开发有限公司 | Tibetan medicine composition and application of composition in anti-off hair products |
| CN107485707A (en) * | 2017-08-03 | 2017-12-19 | 文成当智 | A kind of Tibetan medicinal composition and its application |
| CN108576812A (en) * | 2018-04-27 | 2018-09-28 | 西藏藏医学院 | Composition with fat melting refreshing effect and its processing method |
| CN110101776A (en) * | 2019-06-25 | 2019-08-09 | 西藏圣雪生物科技有限公司 | A kind of Tibetan medicinal composition of hair-growing and anti-hair loss and preparation method thereof |
| CN215938774U (en) * | 2021-05-31 | 2022-03-04 | 西藏自治区藏医院(西藏自治区藏医药研究院) | Intelligent Tibetan medicine miscellaneous vessel Chong pot therapeutic instrument |
Non-Patent Citations (3)
| Title |
|---|
| 六味明目丸治疗迎风流泪的临床疗效;朱业靖;邱进;;中国当代医药;19(24);第124、127页 * |
| 王长海.新编家庭食疗手册.世界图书出版西安公司,2001,第1058页第73小节. * |
| 试论对藏医现代化发展的认识;米玛卓嘎;;中医药管理杂志;14(08);第43-44页 * |
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