CN115397411A - 药物组合及其用途 - Google Patents
药物组合及其用途 Download PDFInfo
- Publication number
- CN115397411A CN115397411A CN202180027954.XA CN202180027954A CN115397411A CN 115397411 A CN115397411 A CN 115397411A CN 202180027954 A CN202180027954 A CN 202180027954A CN 115397411 A CN115397411 A CN 115397411A
- Authority
- CN
- China
- Prior art keywords
- derivative
- ascorbic acid
- inhibitor
- platinum
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
Abstract
一种用于预防和/或治疗肿瘤的药物组合，其包含：a)预防和/或治疗有效量的抗坏血酸或其衍生物；以及b)预防和/或治疗有效量的PDE4选择性抑制剂。
Description
PCT国内申请，说明书已公开。
Claims (73)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010329182 | 2020-04-23 | ||
| CN2020103291822 | 2020-04-23 | ||
| PCT/CN2021/088840 WO2021213455A1 (zh) | 2020-04-23 | 2021-04-22 | 药物组合及其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115397411A true CN115397411A (zh) | 2022-11-25 |
Family
ID=78270282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180027954.XA Pending CN115397411A (zh) | 2020-04-23 | 2021-04-22 | 药物组合及其用途 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230338345A1 (zh) |
| EP (1) | EP4140480A1 (zh) |
| CN (1) | CN115397411A (zh) |
| WO (1) | WO2021213455A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022156727A1 (zh) * | 2021-01-21 | 2022-07-28 | 浙江养生堂天然药物研究所有限公司 | 治疗肿瘤的组合物及方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2075148T3 (es) | 1989-05-19 | 1995-10-01 | Hayashibara Biochem Lab | Acido alfa-glicosil-l-ascorbico, y su preparacion y usos. |
| US5078989A (en) | 1990-03-28 | 1992-01-07 | Sunstar K.K. | Skin whitening cosmetics |
| CA2165192C (en) | 1993-07-02 | 2001-04-24 | Hermann Amschler | Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors |
| KR20040071764A (ko) | 2001-12-28 | 2004-08-12 | 산또리 가부시키가이샤 | ２―Ｏ―（β―Ｄ―글루코피라노실）아스코르브산, 그의제조, 및 이를 함유하는 조성물 포함 식품 및 화장품 |
| CN107007594A (zh) * | 2017-05-08 | 2017-08-04 | 中山大学肿瘤防治中心 | 维生素c和奥沙利铂联用在抗肿瘤中的作用 |
-
2021
- 2021-04-22 US US17/918,604 patent/US20230338345A1/en active Pending
- 2021-04-22 CN CN202180027954.XA patent/CN115397411A/zh active Pending
- 2021-04-22 WO PCT/CN2021/088840 patent/WO2021213455A1/zh unknown
- 2021-04-22 EP EP21793182.3A patent/EP4140480A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021213455A1 (zh) | 2021-10-28 |
| US20230338345A1 (en) | 2023-10-26 |
| EP4140480A1 (en) | 2023-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |