CN115381921A - Traditional Chinese medicine composition and medicinal wax for treating knee osteoarthritis and preparation method thereof - Google Patents
Traditional Chinese medicine composition and medicinal wax for treating knee osteoarthritis and preparation method thereof Download PDFInfo
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- CN115381921A CN115381921A CN202211030109.0A CN202211030109A CN115381921A CN 115381921 A CN115381921 A CN 115381921A CN 202211030109 A CN202211030109 A CN 202211030109A CN 115381921 A CN115381921 A CN 115381921A
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- parts
- wax
- chinese medicine
- traditional chinese
- knee osteoarthritis
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Classifications
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- Bioinformatics & Cheminformatics (AREA)
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Abstract
The invention belongs to the technical field of traditional Chinese medicine formulas, and particularly relates to a traditional Chinese medicine composition for treating knee osteoarthritis, medicinal wax and a preparation method thereof. The traditional Chinese medicine composition comprises, by weight, 2-4 parts of pericarpium zanthoxyli, 2-4 parts of fennel, 2-4 parts of garden balsam stem, 2-4 parts of clematis root, 2-4 parts of Chinese honeylocust fruit, 1-3 parts of rhizoma corydalis, 1-3 parts of ligusticum wallichii, 1-3 parts of radix angelicae pubescentis, 1-3 parts of dried ginger, 0.5-1.5 parts of frankincense and 0.5-1.5 parts of myrrh. The composition can obviously relieve the joint pain of patients and improve the life quality of the patients, and the clinical effective rate is as high as 86%; and the medicinal wax prepared by mixing the medicinal wax with the medical wax is simple to prepare, sanitary, safe and low in price.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine formulas, and particularly relates to a traditional Chinese medicine composition for treating knee osteoarthritis, medicinal wax and a preparation method thereof.
Background
Knee osteoarthritis is a common clinical chronic disease, pathological changes mainly include knee joint cartilage degeneration, subchondral ossification and synovitis, and the main clinical manifestations include knee joint swelling, pain and stiffness, and in severe cases, the knee joint varus deformity can be caused to cause walking disorder. At present, the pathogenesis of knee osteoarthritis is not completely clear, the knee osteoarthritis is considered to be caused by the interaction of mechanical factors and biological factors and is related to factors such as inflammatory infiltration, estrogen deficiency, cytokine synthesis and metabolic disturbance, and the like, and the traditional Chinese medicine belongs to the categories of knee arthralgia, bone arthralgia and the like. The disease is the syndrome of deficiency of the origin and marked excess, and the traditional Chinese medicine considers that the liver governs tendons and the kidney governs bones, if the liver and the kidney are full, the tendons and the bones are strong, the joints are smooth and the movement is flexible. The middle-aged and old people have the problems that the viscera yin and yang qi and blood gradually decline, the yang deficiency cannot warm up the channels, the qi deficiency cannot protect the channels, and the qi and blood circulation is weak, so that the channels are easy to suffer cold dampness; or the body's yang-qi deficiency caused by the damage of yang-qi in cold-damp environment, failing to promote its warming, the body's channels are induced by cold pathogen to stagnate, resulting in unsmooth circulation of qi and blood and pain due to obstruction.
According to statistics, the disease is better for middle-aged and old patients, women are higher than men, the disease rate of people over 45 years old reaches 13.8%, and the disease rate of obese patients is higher. Currently, knee osteoarthritis is one of the main burdens of medical treatment and economy at present, no thorough cure method for the knee osteoarthritis exists in clinic, and serious patients can cause disability along with the development of the disease condition.
Therefore, there is a need for a drug for treating knee osteoarthritis.
Disclosure of Invention
In view of the above problems, an object of the present invention is to provide a Chinese medicinal composition for treating knee osteoarthritis, which can significantly relieve joint pain of patients, improve the quality of life of patients, and achieve a clinical effective rate of 86%.
In order to achieve the purpose, the following technical scheme can be adopted:
the invention provides a traditional Chinese medicine composition for treating knee osteoarthritis, which comprises, by weight, 2-4 parts of pericarpium zanthoxyli, 2-4 parts of fennel, 2-4 parts of garden balsam stem, 2-4 parts of radix clematidis, 2-4 parts of Chinese honeylocust fruit, 1-3 parts of rhizoma corydalis, 1-3 parts of ligusticum wallichii, 1-3 parts of radix angelicae pubescentis, 1-3 parts of dried ginger, 0.5-1.5 parts of frankincense and 0.5-1.5 parts of myrrh.
The invention provides a medicinal wax for treating knee osteoarthritis, which comprises 440-460 parts of medical white wax, 90-110 parts of vaseline, 120-180 parts of water and a traditional Chinese medicine composition for treating knee osteoarthritis according to parts by mass.
In another aspect, the present invention provides a preparation method of the above medicinal wax for treating knee osteoarthritis, which comprises: mixing white wax, vaseline and water, heating to melt, mixing with the Chinese medicinal composition for treating knee osteoarthritis, and cooling to obtain the medicinal wax for treating knee osteoarthritis.
The beneficial effects of the invention at least comprise:
(1) The composition for treating knee osteoarthritis provided by the invention can obviously relieve joint pain of patients and improve the life quality of the patients, and the clinical effective rate is as high as 86%;
(2) The medicinal wax for treating knee osteoarthritis provided by the invention is simple to prepare, sanitary, safe and low in price.
Detailed Description
The examples are given for the purpose of better illustration of the invention, but the invention is not limited to the examples. Therefore, those skilled in the art should make insubstantial modifications and adaptations to the embodiments of the present invention in light of the above teachings and remain within the scope of the invention.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. Unless the context has a significantly different meaning, the singular forms of expressions include the plural forms of expressions. As used herein, it is understood that terms such as "comprising," "having," "including," and the like are intended to refer to the presence of features, numbers, operations, components, parts, elements, materials, or combinations thereof. The terms of the present invention are disclosed in the specification and are not intended to exclude the possibility that one or more other features, numbers, operations, components, parts, elements, materials or combinations thereof may be present or may be added. As used herein, "/" can be interpreted as "and" or "depending on the circumstances.
The embodiment of the invention provides a traditional Chinese medicine composition for treating knee osteoarthritis, which comprises, by weight, 2-4 parts of pericarpium zanthoxyli, 2-4 parts of fennel, 2-4 parts of garden balsam stem, 2-4 parts of radix clematidis, 2-4 parts of Chinese honeylocust fruit, 1-3 parts of rhizoma corydalis, 1-3 parts of ligusticum wallichii, 1-3 parts of radix angelicae pubescentis, 1-3 parts of dried ginger, 0.5-1.5 parts of frankincense and 0.5-1.5 parts of myrrh.
In some embodiments, the traditional Chinese medicine composition for treating knee osteoarthritis comprises, by weight, 3 parts of pericarpium zanthoxyli, 3 parts of fennel, 3 parts of garden balsam stem, 3 parts of clematis root, 3 parts of Chinese honeylocust fruit, 2 parts of rhizoma corydalis, 2 parts of ligusticum wallichii, 2 parts of radix angelicae pubescentis, 2 parts of rhizoma zingiberis, 1 part of frankincense and 1 part of myrrh.
In the traditional Chinese medicine composition for treating knee osteoarthritis, the radix angelicae pubescentis in the formula is used for removing chronic arthralgia and dispelling wind-cold-dampness between lower energizer and bones; clematis root and garden balsam stem can dispel wind-damp and dredge channels and collaterals; the pericarpium zanthoxyli, the fennel and the dried ginger are combined to play a role in warming meridians, dispelling cold and relieving pain; fructus Gleditsiae Abnormalis and rhizoma corydalis can relieve swelling and pain, and rhizoma Ligustici Chuanxiong, olibanum and Myrrha can promote blood circulation, remove obstruction in collaterals, and relieve arthralgia; the Chinese medicinal composition has effects of warming channels for dispelling cold, and relieving swelling and pain; in addition, the radix angelicae pubescentis can reduce the secretion of inflammatory mediators IL-1 in synovial fluid, relieve synovium inflammation, promote the secretion of TGF-beta and relieve the damage of chondrocytes; the clematis root and the garden balsam stem have obvious analgesic and anti-inflammatory effects.
The invention also provides medicinal wax for treating knee osteoarthritis, which comprises 440-460 parts of medicinal white wax, 90-110 parts of vaseline, 120-180 parts of water and a traditional Chinese medicine composition for treating knee osteoarthritis according to parts by mass. It should be noted that the above traditional Chinese medicine composition for treating knee osteoarthritis may be a traditional Chinese medicine composition known in the art, and is preferably the traditional Chinese medicine composition for treating knee osteoarthritis provided in the present invention, i.e., the above traditional Chinese medicine composition for treating knee osteoarthritis.
In some specific implementations, the medicinal wax for treating knee osteoarthritis comprises 450 parts of medicinal white wax, 100 parts of vaseline, 150 parts of water and a traditional Chinese medicine composition for treating knee osteoarthritis by mass parts.
Another embodiment of the present invention provides a preparation method of the above medicinal wax for treating knee osteoarthritis, comprising: mixing white wax, vaseline and water, heating for melting, mixing with the Chinese medicinal composition for treating knee osteoarthritis, and cooling to obtain medicinal wax for treating knee osteoarthritis. It should be noted that the purpose of heating and melting is to make it into paste, which is convenient for mixing with the Chinese medicinal composition powder. Similarly, the traditional Chinese medicine composition for treating knee osteoarthritis in the preparation method can be a traditional Chinese medicine composition known in the art, and preferably the traditional Chinese medicine composition for treating knee osteoarthritis provided by the invention, namely the traditional Chinese medicine composition for treating knee osteoarthritis.
It is to be noted that the traditional Chinese medicine accumulates abundant clinical experiences in internal and external therapies for treating knee osteoarthritis, such as traditional Chinese medicine inunction, wax therapy, acupoint application, traditional Chinese medicine fumigation and the like of the external therapy of the traditional Chinese medicine, and has good clinical effects. The 2001 edition of guidelines for diagnosis and treatment of osteoarthritis indicates that local external treatment is firstly suggested for the treatment of knee osteoarthritis, and wax treatment is recorded in the Beijing Simiao's Provisions of thousand gold wing, wherein it is mentioned that wax treatment is given after manual reduction of mandibular joint dislocation, which can promote joint reduction. The wax therapy has wide clinical application and good effect of treating knee osteoarthritis. The warm function of the pure medical paraffin after heating and dissolving can expand local capillary vessels, promote blood circulation to increase capillary permeability, accelerate epithelial cell growth to enable local exudation and absorption, and is beneficial to tissue regeneration and repair. Specifically, the paraffin wax is continuously reduced in volume in the cooling process, and the generated local mechanical compression effect can prevent lymph fluid and blood in the tissue from exuding, relieve tissue edema, make close contact with the skin, and transmit warm heat to deep tissues, thereby playing the roles of diminishing inflammation, relieving spasm and easing pain.
It should also be noted that the traditional Chinese medicine wax therapy is a traditional Chinese medicine characteristic therapy combining the modern technology and the traditional Chinese medicine, which is based on the guidance of the theory of traditional Chinese medicine, is applied to the affected part by combining the traditional Chinese medicine and the medical paraffin to achieve the effects of promoting blood circulation to remove blood stasis, eliminating dampness and cold, warming and dredging the channels and collaterals and the like. In addition, the traditional Chinese medicine composition can be fused with the warming effect and the mechanical compression effect of paraffin, so that the traditional Chinese medicine and the keritherapy are mutually enhanced to treat knee osteoarthritis. In a word, the traditional Chinese medicine wax therapy integrates the functions of traditional Chinese medicine transdermal absorption, acupoint stimulation, thermotherapy and the like, has quick, simple and convenient action, low price, safety and small toxic and side effects, and is a measure for commonly treating painful diseases in the rehabilitation department, the pain department and the rheumatism department at present.
In addition, the traditional Chinese medicine wax therapy in clinic mostly adopts the separation technology of traditional Chinese medicine and medical wax, the preparation of the medical wax needs to be equipped with a full-automatic wax making machine, the cost is high, the temperature of the wax block is not easy to master, the wax block needs to be repeatedly sterilized and reused, and the operation is complicated. The traditional Chinese medicine composition for treating knee osteoarthritis is uniformly mixed with the medical wax, and the preparation method is simple, one part is used by one person, and the traditional Chinese medicine composition is sanitary, safe and low in cost; moreover, after clinical curative effect evaluation, the medicinal wax can obviously relieve joint pain of patients and improve the life quality of the patients, and the clinical effective rate can reach 86%.
It is also noted that when the medicinal wax for treating knee osteoarthritis is used, the traditional Chinese medicine and the medicinal wax can directly contact the skin of an affected part, so that the operation is simple and the medicinal wax is convenient to master; it has no influence on the curative effect of Chinese medicine and the thermotherapy and mechanical action of wax, ensures the balance of medicine at the affected part, and enhances the curative effect of local treatment of Chinese medicine and wax; moreover, the operation flow method is simple, convenient, effective and cheap, and the satisfaction degree of the patient is improved.
For a better understanding of the present invention, the following further illustrates the contents of the present invention with reference to specific examples, but the contents of the present invention are not limited to the following examples.
1. Preparation of cerate
EXAMPLE 1 preparation of Chinese medicinal wax ointment
Grinding 3 parts of pericarpium zanthoxyli, 3 parts of fennel, 3 parts of garden balsam stem, 3 parts of clematis root, 3 parts of Chinese honeylocust fruit, 2 parts of rhizoma corydalis, 2 parts of ligusticum wallichii, 2 parts of radix angelicae pubescentis, 2 parts of rhizoma zingiberis, 1 part of frankincense and 1 part of myrrh into fine powder for later use; 450 g of medical white wax, 100 g of vaseline and 150 ml of water are put into a plastic microwave special preservation box (bag cover) with the specification of 1200 ml, the mixture is heated for 15 minutes by using a microwave oven with medium fire, 250 g of the medicinal powder is added after the white wax is melted, the mixture is uniformly mixed, and the prepared traditional Chinese medicine cerate is obtained after cooling.
Comparative example 1 preparation of ordinary cerate
450 g of medical white wax, 100 g of vaseline and 150 ml of water are taken and put into a plastic microwave special preservation box (bag cover) with the specification of 1200 ml, the mixture is heated for 15 minutes by using a microwave oven with medium fire, edible coloring agent is added after the white wax is melted, the mixture is uniformly mixed, and the prepared common cerate is obtained after cooling.
2. Wax ointment efficacy verification
In this validation experiment, the temperature was maintained in the treatment room at 24-30 ℃; warm boiled water is drunk in a proper amount before and after the wax therapy, and the bath is not needed 3 to 4 hours after the wax therapy, and cold air is not needed to blow; accurately controlling the temperature of the wax, uniformly applying the wax, quickly taking action medicine, and immediately checking if a patient feels pain; after the wax therapy, the patient must discard all old wax and replace the old wax with new wax block to reflect the skin discomfort; after the treatment is finished, people can go out after wearing the clothes for half an hour to prevent cold wind; 1 time every day, each time is about 30 minutes, 15 times are 1 treatment course, and rest is carried out for 2 days in the treatment course, and 2 treatment courses are total; the wax can be repeatedly used, one person can use the wax in one box, and the wax is recommended to be used for 20 times optimally, so that the wax and the optimal components of the traditional Chinese medicine can be exerted.
In the verification test, patients have pain induction and are immediately checked after wax therapy, and the treatment is stopped immediately when rash appears at the treatment part, so that the symptoms are relieved; when the wax therapy is carried out, the affected part can be covered with a layer of vaseline gauze for treatment if the skin of the affected part is cracked, and the local part has ulcer or wound, the affected part is firstly washed with potassium permanganate solution, and then is covered with a thin wax film for treatment; the small bleb appears in the area, which can help the patient to protect the bleb, avoid ulceration, allow the patient to absorb the bleb, and heal the bleb generally in 2-5 days. If the water bubble is large, the disinfecting needle can be used to puncture the water bubble, discharge water, and apply scald oil on the external surface to keep the wound clean, and the wound can be cured in several days.
In the verification test, 100 patients with knee osteoarthritis who come from the first clinical hospital of the department of traditional Chinese medicine academy of sciences in Jilin and the third subsidiary hospital of the university of vinpocetine, 1 month to 2021 month and 9 months are selected as study subjects. The treatment group and the control group are randomly divided into 50 cases. Treatment group 50, 16 men and 34 women; age minimum 51 years, maximum 77 years, mean (55.41 ± 7.61) years; the average course of disease is 3.71 + -2.12 years. A control group of 50, 18 men and 32 women; age minimum 50 years, maximum 74 years, mean (54.15 ± 8.01) years; the mean course of disease is 3.82 + -1.91 years. Both groups of patients were statistically insignificant in terms of gender, age, course of disease, etc. (P > 0.05). The research conforms to the ethical requirements of Helsinki declaration, and the ethical examination number is as follows: JLSZKYLL2020 examine character-016.
In the verification test, the diagnosis standard of the western medicine is as follows: referring to the bone fracture department division of the Chinese medical society, bone joint diagnosis and treatment guideline (2007 edition) (1), knee joint pain repeatedly occurs in nearly 1 month; (2) x-ray film (standing or loading position) shows joint space narrowing, subchondral bone sclerosis and/or cystic change, joint marginal osteophyte formation; (3) synovial fluid (at least 2 times) is clear, viscous, WBC < 2000/ml; (4) the patient is over 40 years of age; (5) morning stiffness of less than 30 minutes; (6) the bone rubbing feeling is generated during the activity; the diagnosis of knee osteoarthritis can be carried out according to the (1) + (2) or (1) + (3) + (5) + (6) or (1) + (4) + (5) + (6) by combining clinical, laboratory and X-ray examination.
In the verification test, the traditional Chinese medicine syndrome diagnosis standard is as follows: refer to the TCM diagnosis and treatment expert consensus for knee osteoarthritis (2015) and the Ministry of health of the people's republic of China in 1993 to formulate and issue the clinical research guidelines for new Chinese medicines [15] And (5) formulating. Traditional Chinese medicine syndrome differentiation and typing: syndrome of cold-dampness obstruction. The main symptoms are: cold pain of the knee joint; soreness and heaviness of the waist and knees; aggravated by cold, the pain relieved by heat. The secondary symptoms are as follows: joint swelling; the bending and stretching are not good; the local skin color is not larger than the great value and is not hot to touch; aversion to wind-cold. Tongue pulse: pale-red or purple-dark tongue with thin, white or white greasy coating and wiry, tense, deep, thready, astringent or soft-superficial slow pulse.
In the verification test, the volunteer accords with the Chinese and western medicine diagnosis standard, the patient with early and middle knee osteoarthritis is 45-80 years old and unlimited in sex, volunteers participate in the test study, and signs an informed consent; volunteers are not women in lactation and pregnancy, are not allergic patients, and are not patients with serious primary diseases and mental diseases such as heart, brain, liver, kidney, hematopoietic system, endocrine system and the like.
In the verification test, the therapeutic effect judgment standard is as follows: evaluation of painThe VAS score is adopted, the score is 10 points in total, and the high score indicates that the patient has severe pain. Knee joint function scoring using Lysholm [18] The functions of the patient such as support, squatting, knee softness, pain, lameness, twistlock, swelling, stair ascending and descending are evaluated, the total score is 100 points, and the high score indicates that the knee joint function of the patient is good. The standard of curative effect refers to the evaluation standard of curative effect of bone impediment in the diagnosis and treatment standard of traditional Chinese medicine diseases. And (3) curing: the calculation result is more than or equal to 90 percent, the arthralgia disappears, and the swelling, the activity function and the physical signs disappear completely; the effect is shown: the calculation result is more than or equal to 70 percent when the ratio is more than 90 percent, the joint pain disappears, and the swelling, the activity function and the physical signs are obviously reduced; the method has the following advantages: the calculation result is more than 70% and more than or equal to 30%, and the joint pain disappears, and the swelling, the activity function and the physical signs are reduced; and (4) invalidation: the calculated result is less than 30% and the joint pain disappears, swelling, activity function and physical signs are not improved.
In the verification test, SPSS20.0 statistical software is adopted for data processing and analysis, counting data is expressed in terms of rate and X is used 2 Checking and measuring data
It is shown that P <0.05 is statistically significant by t-test.
Example 2 experimental verification
Putting a box of prepared cerate into a microwave oven, dissolving the medicinal wax to about 50-60 degrees (no long-time high-temperature heating is needed to avoid wax damage when the wax is dissolved) by using a medium fire for 5 minutes, taking out the medicinal wax, uniformly turning over the dissolved medicinal wax by using a wooden shovel, smearing the medicinal wax at the knee joint of a patient when the medicinal wax is stably reduced to 40-45 degrees (the temperature can be properly adjusted according to different tolerance degrees of the patient and is subject to tolerance of the patient) and covering the whole knee joint of the patient as much as possible, wherein the thickness of the medicinal wax is about 1.5 cm; covering a disposable plastic film and a thick towel on the cerate for heat preservation; the treatment group used the herbal wax ointment prepared in example 1; the control group used the general cerate prepared in comparative example 1. Both groups used a basal treatment regimen: reference is made to the 2010 osteoarthritis diagnosis and treatment guide of the Chinese medical society rheumatology division; the treatment is performed 1 time per day, each time is about 30 minutes, 1 treatment course is 10 times, and 2 treatment courses are performed with rest in the course of treatment for 2 days.
The treatment course effect is judged according to the treatment effect judgment standard, and the treatment course effect is as follows:
(1) Comparison of knee pain VAS scores
The results of comparison of the VAS scores for knee pain are shown in table 1 below, wherein the difference between the scores of two groups of patients before treatment is no statistical significance P >0.05, the difference between the scores of two groups after treatment is significantly lower than that before treatment, the difference is statistical significance P <0.05, and the difference between the scores of two groups is no statistical significance P >0.05.
Table 1 knee pain VAS scores (score,
)
| group of | Before treatment | After treatment |
| Treatment group | 6.29±1.23# | 3.51±1.22*△ |
| Control group | 6.18±1.21 | 3.89±1.34* |
Note: comparison of # P >0.05 between the two groups before treatment, # P <0.05 between the two groups before and after treatment, and comparison of Δ P >0.05 between the two groups after treatment.
(2) Knee function Lyshlom score
Knee joint function Lyshlom score results are shown in table 2 below, with no statistically significant P >0.05 for the two groups of patients before treatment, with statistically significant P <0.05 for both groups after treatment, and with a comparison between the two groups that is superior to the control group P <0.05.
Table 2Lyshlom knee function score (points,
)
| group of | Before treatment | After treatment |
| Treatment group | 43.14±2.51# | 67.35±2.23*▲ |
| Control group | 42.72±2.04 | 47.48±2.61* |
Note: comparison of # P >0.05 in the first two groups, comparison before and after treatment of two groups, # P <0.05, comparison between the two groups after treatment, a-P <0.05.
(3) Comparison of clinical efficacy
The clinical efficacy comparison results are shown in table 3 below, the total effective rate of the treatment group is 86%, and the total effective rate of the control group is 70%, which is higher than that of the control group (p < 0.05).
Table 3 comparison of clinical effects of the two groups (%)
Note: two groups compared,. P <0.05.
The following verification results show that the treatment group and the control group can obviously relieve the joint pain of the patient and improve the life quality of the patient, and both the VAS score and the Lysholm knee joint score before and after treatment have statistical significance; the clinical effective rate of the treatment group is 86 percent, the clinical effective rate of the control group is 70 percent, and the comparison treatment group between the two groups is superior to the control group.
Finally, the above embodiments are only intended to illustrate the technical solution of the present invention and not to limit the same, and although the present invention has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention, which shall be covered by the claims of the present invention.
Claims (6)
1. A traditional Chinese medicine composition for treating knee osteoarthritis is characterized by comprising, by weight, 2-4 parts of pericarpium zanthoxyli, 2-4 parts of fennel, 2-4 parts of garden balsam stem, 2-4 parts of radix clematidis, 2-4 parts of saponin, 1-3 parts of rhizoma corydalis, 1-3 parts of ligusticum wallichii, 1-3 parts of radix angelicae pubescentis, 1-3 parts of rhizoma zingiberis, 0.5-1.5 parts of frankincense and 0.5-1.5 parts of myrrh.
2. The traditional Chinese medicine composition for treating knee osteoarthritis according to claim 1, which comprises, by weight, 3 parts of pericarpium zanthoxyli, 3 parts of fennel, 3 parts of garden balsam stem, 3 parts of radix clematidis, 3 parts of Chinese honeylocust fruit, 2 parts of rhizoma corydalis, 2 parts of ligusticum wallichii, 2 parts of radix angelicae pubescentis, 2 parts of rhizoma zingiberis, 1 part of frankincense and 1 part of myrrh.
3. The medicinal wax for treating knee osteoarthritis is characterized by comprising 440-460 parts of medical white wax, 90-110 parts of vaseline, 120-180 parts of water and a traditional Chinese medicine composition for treating knee osteoarthritis in parts by mass.
4. The medicinal wax for treating knee osteoarthritis according to claim 3, which is characterized by comprising 450 parts of medical white wax, 100 parts of vaseline, 150 parts of water and a traditional Chinese medicine composition for treating knee osteoarthritis according to parts by mass.
5. The wax for treating knee osteoarthritis according to claim 3 or 4, wherein the traditional Chinese medicine composition for treating knee osteoarthritis is selected from the traditional Chinese medicine composition for treating knee osteoarthritis according to claim 1 or 2.
6. The method for preparing the medicinal wax for treating knee osteoarthritis according to any one of claims 3 to 4, comprising the following steps:
mixing white wax, vaseline and water, heating to melt, mixing with the Chinese medicinal composition for treating knee osteoarthritis, and cooling to obtain the medicinal wax for treating knee osteoarthritis.
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| CN105582514A (en) * | 2016-02-22 | 2016-05-18 | 宋庆国 | Medical physiotherapy wax and preparation technology thereof |
| CN111632096A (en) * | 2020-06-29 | 2020-09-08 | 临沂职业学院 | Biological wax composition for treating osteoarthritis and preparation method thereof |
| CN114869946A (en) * | 2022-06-15 | 2022-08-09 | 河南中医药大学第一附属医院 | Traditional Chinese medicine wax moxibustion phase change paste and preparation and use methods thereof |
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| CN105582514A (en) * | 2016-02-22 | 2016-05-18 | 宋庆国 | Medical physiotherapy wax and preparation technology thereof |
| CN111632096A (en) * | 2020-06-29 | 2020-09-08 | 临沂职业学院 | Biological wax composition for treating osteoarthritis and preparation method thereof |
| CN114869946A (en) * | 2022-06-15 | 2022-08-09 | 河南中医药大学第一附属医院 | Traditional Chinese medicine wax moxibustion phase change paste and preparation and use methods thereof |
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