CN115364135A - External inflammation treatment composition and preparation method and application thereof - Google Patents

External inflammation treatment composition and preparation method and application thereof Download PDF

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Publication number
CN115364135A
CN115364135A CN202211050232.9A CN202211050232A CN115364135A CN 115364135 A CN115364135 A CN 115364135A CN 202211050232 A CN202211050232 A CN 202211050232A CN 115364135 A CN115364135 A CN 115364135A
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CN
China
Prior art keywords
powder
inflammation
composition
cactus
stasis
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Application number
CN202211050232.9A
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Chinese (zh)
Inventor
刘海弘
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Xiangyun County Hospital Of Traditional Chinese Medicine
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Xiangyun County Hospital Of Traditional Chinese Medicine
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Publication date
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Priority to CN202211050232.9A priority Critical patent/CN115364135A/en
Publication of CN115364135A publication Critical patent/CN115364135A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/33Cactaceae (Cactus family), e.g. pricklypear or Cereus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Abstract

The invention discloses a composition of a traditional Chinese medicine external treatment method for inflammation and a preparation method and application thereof, the composition comprises antiphlogistic stasis-resolving powder and a blending medium, wherein the blending medium is fresh cactus juice, and the antiphlogistic stasis-resolving powder consisting of borneol, frankincense, myrrh and cactus powder is added, and the antiphlogistic stasis-resolving powder and the blending medium are mutually used and are mutually synergistic, so that the antiphlogistic stasis-resolving powder has the effects of promoting blood circulation and promoting qi circulation, and relieving swelling and pain obviously. The inflammation diminishing and stagnation eliminating powder and the fresh wild cactus are mixed according to a specific proportion and then are manufactured into acupuncture points for application and externally applied to the body surface of a focus, so that the effects of clearing heat, diminishing inflammation, promoting blood circulation and eliminating stagnation are achieved, the skin feeling is cool, the medicine is easy to accept, and the diagnosis and treatment effects of the diseases are improved.

Description

External treatment composition for inflammation as well as preparation method and application thereof
Technical Field
The invention relates to a traditional Chinese medicine composition for externally treating inflammation, in particular to an externally treating composition for inflammation and a preparation method and application thereof.
Background
Derived from a folk prescription of Bai nationality, namely pure Chinese herbal medicine, the cactus is recorded in the book to have the functions of clearing heat and detoxicating, and reducing swelling and eliminating stagnation, and the mashed cactus is taken as a juice, and a small amount of ice tablets are added for external use to treat parotitis, mastitis, carbuncle, furuncle and venomous snake bite. The modern research shows that the meat stems of cactus are rich in colloid starch, and the fruits contain components such as saccharides, proteins, various amino acids and the like. Has effects of clearing away heat and toxic materials and enhancing immunity. Has obvious inhibition effect on acute inflammation and chronic inflammation, and the cactus water extract can also improve digestion. The cactus is used by folk experience at present, is simply ground and externally used by single herb, is inconvenient to carry, does not prolong the day after storing medicines, has single effect, and has few reports on the effect of the plant on the antibacterial and antiseptic abilities.
Disclosure of Invention
The invention aims to provide a composition of a traditional Chinese medicine external treatment method for inflammation, a preparation method and application thereof aiming at the defects in the prior art. The blending medium of the invention is fresh cactus juice, and borneol, frankincense, myrrh and cactus powder are added, so that the invention has obvious effects of activating blood circulation, promoting qi circulation, and relieving swelling and pain. The functions of all the substances in the composition are similar, and no side effect of rejection of any medicine exists, all the substances are mutually reinforced and mutually cooperated, so that the effect of clearing heat, removing toxicity and diminishing inflammation of the formula is more obvious, the lump is treated at the same time, the adaptation diseases are widened, and the symptoms of sore throat and swelling of the body of a patient can be treated by using the composition. The invention prepares the inflammation diminishing and stagnation eliminating powder into the acupoint application, is convenient to carry and prolongs the medicine period. Clinical application shows that the formula has obvious effect on acute and chronic tonsillitis, parotitis, angina, lymphadenitis and benign mass of the whole body. The effective rate of hospitalization for acute tonsillitis and acute suppurative tonsillitis is 98% (calculated according to the discharge cure rate), and the effective rate of treatment for acute inflammatory lymphadenectasis and body surface mass is 60% (outpatient treatment rate). However, the medicine has short storage time after being prepared by taking fresh cactus and borneol.
The invention is realized by the following technical scheme: a composition for external treatment of inflammation traditional Chinese medicine comprises anti-inflammation and stasis-removing powder and a blending medium, wherein the anti-inflammation and stasis-removing powder comprises 4-6 parts by weight of cactus powder and 1-3 parts by weight of borneol, frankincense and myrrh respectively, the blending medium is fresh cactus juice, and the ratio of the blending medium to the anti-inflammation and stasis-removing powder is 1 part by weight.
Preferably, the anti-inflammatory and stasis-removing powder is composed of 5 parts of cactus powder and 2 parts of borneol, frankincense and myrrh respectively, and the proportion of the mixing medium to the anti-inflammatory and stasis-removing powder is 1.
Preferably, the fresh cactus juice is prepared by taking fresh wild cactus, removing spines, peeling, taking pulp, and mashing to obtain juice; grinding Borneolum Syntheticum, olibanum and Myrrha respectively with a powder grinding machine to obtain powder less than 120 mesh, mixing, adding radix et caulis Opuntiae Dillenii powder and radix et caulis Opuntiae Dillenii juice, blending to obtain viscous state without dripping, and adding patch applied on acupuncture point.
The invention discloses a preparation method of a composition for external treatment of inflammation, which is defined in claim 1, and comprises the following steps:
(1) Taking fresh wild cactus, removing spines and peels, taking pulp, and mashing to obtain juice;
(2) Respectively taking borneol, frankincense and myrrh, and grinding by using a grinding machine to obtain powder particles with a particle size less than 120 meshes;
(3) Mixing 5 parts of radix et caulis Opuntiae Dillenii powder and 2 parts of Borneolum Syntheticum, olibanum and Myrrha powder respectively to obtain a viscous state without dripping, and placing into an acupoint application container.
(4) The cactus juice and the Chinese medicinal powder are mixed and placed on a patch at normal temperature, so that the cactus powder is convenient to carry, is not added with any preservative, and can be preserved for 72 hours at 4-8 ℃ in a conventional preservation manner.
Preferably, the acupoint application container is a patch.
The invention relates to an application of a composition of a traditional Chinese medicine external treatment method for inflammation, which is used for treating acute and chronic tonsillitis, angina, parotitis, lymphadenitis and/or benign mass of the whole body by external application.
Preferably, it is applied to children aged 3-9 years.
The children physique is young in yin and yang, the lung is often insufficient, so the children physique is easy to be invaded by exogenous pathogenic factors, respiratory diseases are frequently generated, the throat is the place where the respiratory tract is to be blocked, and acute and chronic tonsillitis, angina and parotitis are frequently encountered in pediatric common diseases, but the children compliance is poor, and the treatment modes such as atomization, oral administration and the like cannot be completely matched.
Detailed Description
The following description of the preferred embodiments of the present invention is provided for the purpose of illustration and description, and is in no way intended to limit the invention.
The finished cactus powder, chinese herbal pieces borneol, frankincense and myrrh in the market are purchased in hospitals, wherein the borneol, the frankincense and the myrrh are ground by a grinding machine to obtain powder particles smaller than 120 meshes, and the powder particles are mixed according to the weight parts of 2 parts of the borneol powder, 2 parts of the frankincense powder, 2 parts of the myrrh powder and 5 parts of the cactus powder to obtain the inflammation diminishing and stasis removing powder;
taking fresh wild cactus, removing spines and peels, taking pulp, mashing and taking juice to obtain a blending medium;
the mixing medium and the anti-inflammatory and stagnation-removing powder are mixed according to the proportion of 1 part by weight to 2 parts by weight to achieve a moist and non-dripping viscous state, and the mixture can be used in patches purchased and supplied in hospital markets and is divided into three specifications of large, medium and small according to the application area. When in use, the paste is directly applied to the surface of a lesion body, and can be used after being mixed at normal temperature in the same day, and can be stored for 72 hours after being preserved at the temperature of 4-8 ℃.
The composition has remarkable curative effect on acute and chronic tonsillitis, angina, parotitis, lymphadenitis and benign mass of the whole body. For acute tonsillitis and acute suppurative tonsillitis, the effective rate of hospitalization is 98% (calculated by the discharge cure rate), and the applicant has received treatment on infantile tonsillitis (acute or chronic tonsillitis), with the cure rate of 98%. The effective rate of the treatment for acute inflammatory lymphadenectasis and body surface mass is 60 percent (outpatient treatment rate). The outpatient treatment frequency is increased from 3217 to 2021 in 2019 to 5530.
Some examples of effects are given below:
1. effect example 1: the invention provides a method for treating infantile tonsillitis (acute or chronic tonsillitis) 866 in 5-2022-15 days in 2018, wherein the cure rate is 98%, the composition is involved in 100% of treatment, the effect is obvious in 850 cases, the effect is effective in 12 cases, and the effective rate is 100%. The clinical application individual case of the inflammation diminishing and stasis removing powder for treating acute and chronic tonsillitis in the implementation of the item is provided.
Ruiyizi, hospitalization No. 82551, male, 3 years old, 2 groups of infants and young children admitted 3 days for fever and angina after completing relevant examination, diagnosed as acute tonsillitis, and applied to the double mandible of the external application of anti-inflammation and stasis-dissipating powder for 1 time a day and 5-8 hours each time after completing relevant examination, wherein the infants are not heated and angina, and are cured and discharged.
Lijiang, clinic No. 3723373, women, 5 years old, 20 groups of people in Dana village in Liu factory town of Ping county, anhui province, california, and diagnosed as chronic tonsillitis clinic treatment due to repeated tonsil infection for more than 2 months. The composition of the invention is externally applied to the mandible for 1 time a day, each time is 5-8 hours, the continuous treatment is carried out for 10 days, the pharyngalgia of the children patients is relieved, and the tonsil swelling on the two sides is relieved.
2. Effect example 2: the effect example provides an individual case of clinical application of the composition of the invention in treating facial cellulite infection. Hu, hospital admission 62642, woman, 6 years old, 4 groups of students of the yellow family village committee in auspicious town of auspicious cloud county, dali white nation of Yunnan province. The patient is admitted to the hospital for 1 day of double-side swelling and pain of the febrile school, and after the relevant examination is completed, the patient is diagnosed with the facial cellulitis and the acute tonsillitis, and the anti-inflammatory and stasis removing powder is externally applied to the facial swelling part for 1 time every day and 5-8 hours every time for 7 days of continuous treatment, so that the infant patient has no fever, and the facial swelling and pain disappear.
3. Effect example 3: the effect example provides a clinical application individual case of the composition for treating acute cervical lymphadenitis. Yangzhi, no. 77485, female, 9 years old, 4 groups of people in the yellow family village committee of the auspicious county of white city, university of Yunnan province, students, patients, because of finding that the left neck is swollen and painful to admit hospital for half a day, perfect relevant auxiliary inspection after admission, diagnose as acute neck lymphadenitis, give the antiphlogistic nodulation dissipating powder to externally apply to the bilateral progress swelling part, 1 time a day, 5-8 hours each time, treat for 7 days continuously, neck lymphadenectasis of the children is resolved, and the pain disappears.
4. Effect example 4: the effect example provides a clinical application individual case of the composition for treating parotitis, namely Jiangzhi, a hospital number 70029, a man, a 5-year-old person, 1 group of people of Xiang town Huang family village Commission in Xiang Yun county, calif. Yunnan, students, and children patients are admitted into the hospital for 1 day because of left-side face swelling and pain, and relevant auxiliary examination is perfected after admission, and the diagnosis is as follows: acute parotitis, and acute cervical lymphadenitis. The anti-inflammatory and stasis-removing powder is externally applied to the swelling areas on two sides, 1 time a day, 5-8 hours each time, and the treatment is continuously carried out for 7 days, so that the swelling on the face of the child patient is relieved, and the pain disappears.
5. Effect example 5: the effect example provides a clinical application individual case of the composition for treating parotitis, which is high, the hospital number is 86048, women are 7 years old for 2 months, 1 group in the urban south of auspicious county in auspicious county of white nationality in Yunnan province, students and children are admitted to the hospital for 2 days due to heat, relevant auxiliary examination is perfected after admission, acute angina is diagnosed, the anti-inflammation and stasis-removing powder is externally applied to the bilateral progress swelling part for 5 days, the treatment is carried out for 1 time every day and 5-8 hours every time, the face swelling of the children is removed, and the pain disappears.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or that equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. The composition of the traditional Chinese medicine external treatment method for inflammation is characterized by comprising 4-6 parts by weight of cactus powder and 1-3 parts by weight of each of borneol, frankincense and myrrh as well as a blending medium, wherein the blending medium is fresh cactus juice, and the blending medium and the inflammation diminishing and stasis dissipating powder are mixed according to the weight ratio of 1.
2. The composition of claim 1, wherein the powder of the anti-inflammatory and stasis-resolving powder comprises 5 parts of cactus powder, 2 parts of each of borneol, frankincense and myrrh, and the ratio of the mixing medium to the powder of the anti-inflammatory and stasis-resolving powder is 1.
3. The composition for the external treatment of inflammation according to claim 1, wherein the fresh cactus juice is prepared by taking fresh wild cactus, removing spines and peels, taking pulp, and mashing to obtain juice; grinding Borneolum Syntheticum, olibanum and Myrrha with a grinding machine to obtain powder with a particle size less than 120 meshes, mixing, adding radix et caulis Opuntiae Dillenii powder and radix et caulis Opuntiae Dillenii juice, blending to obtain viscous state without dripping, and adding patch applied on acupuncture point.
4. The preparation method of the composition for the traditional Chinese medicine external treatment of inflammation according to claim 1 is characterized by comprising the following steps:
(1) Taking fresh wild cactus, removing spines and peels, taking pulp, and mashing to obtain juice;
(2) Respectively taking borneol, frankincense and myrrh, and grinding by using a grinding machine to obtain powder particles with a particle size less than 120 meshes;
(3) Mixing 5 parts of radix et caulis Opuntiae Dillenii powder, and 2 parts of Borneolum Syntheticum, olibanum and Myrrha powder respectively to obtain a viscous state without dripping, and placing into an acupoint application container;
(4) The fresh-keeping agent can be used after being mixed at normal temperature in the day, and can be stored for 72 hours after being kept fresh for 4-8 ℃.
5. The method for preparing an external composition for treating inflammation as claimed in claim 4, wherein the acupoint application container is a patch.
6. The use of a composition for external treatment of inflammation with traditional Chinese medicine, which is characterized in that the composition for external treatment of inflammation with traditional Chinese medicine comprises the composition for external treatment of inflammation with traditional Chinese medicine of any one of claims 1 to 3, and is used for treating acute and chronic tonsillitis, angina, parotitis, lymphadenitis and/or benign mass of the whole body by external application.
CN202211050232.9A 2022-08-31 2022-08-31 External inflammation treatment composition and preparation method and application thereof Pending CN115364135A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211050232.9A CN115364135A (en) 2022-08-31 2022-08-31 External inflammation treatment composition and preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202211050232.9A CN115364135A (en) 2022-08-31 2022-08-31 External inflammation treatment composition and preparation method and application thereof

Publications (1)

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CN115364135A true CN115364135A (en) 2022-11-22

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1349821A (en) * 2001-11-01 2002-05-22 赵健忠 Pharyngitis treating Chinese medicine plaster
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN110302325A (en) * 2019-07-16 2019-10-08 刘本维 A kind of external use health cream and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1349821A (en) * 2001-11-01 2002-05-22 赵健忠 Pharyngitis treating Chinese medicine plaster
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN110302325A (en) * 2019-07-16 2019-10-08 刘本维 A kind of external use health cream and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张汝波;: "仙冰膏外敷治疗流行性腮腺炎80例", 实用中医药杂志, vol. 23, no. 03, pages 1 *

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