CN115363975A

CN115363975A - After-sun soothing and repairing composition and application thereof

Info

Publication number: CN115363975A
Application number: CN202211150330.XA
Authority: CN
Inventors: 陈家欢; 孟丽; 吴忠利; 聂舟; 王晓慧
Original assignee: Guangzhou Rui Sen Biotechnology Co ltd
Current assignee: Guangzhou Rui Sen Biotechnology Co ltd
Priority date: 2022-09-21
Filing date: 2022-09-21
Publication date: 2022-11-22

Abstract

The invention provides a post-basking soothing and repairing composition comprising: 0.5 to 3 parts by weight of DNA sodium; 0.4 to 1.5 parts by weight of plankton extract; 0.1 to 0.5 weight portion of resveratrol; 1 to 20 portions of ectoin. Compared with the prior art, the composition provided by the invention has the advantages that through mutual cooperation of the components, the skin can be relieved, the skin calming effect is realized, the effective water replenishing is realized on the skin, the symptoms of redness, stabbing pain, itching and the like after the skin is exposed to the sun are effectively improved, meanwhile, free radicals generated by ultraviolet irradiation can be timely eliminated, the generation of melanin is inhibited, and the skin is helped to recover health.

Description

After-sun soothing and repairing composition and application thereof

Technical Field

The invention belongs to the technical field of cosmetics, and particularly relates to a after-sun soothing and repairing composition and application thereof.

Background

In summer with inflammation, not only is protection before sunning required, but also after sunning, the protection is necessary, and even if the protection is good, the damage caused by ultraviolet rays cannot be isolated in a hundred percent. The long-term exposure to ultraviolet rays can cause the phenomena of pigmentation, sunburn, skin dehydration and aging, inflammation, reddening and burning, desquamation and the like, and if the ultraviolet rays invade the inside of the skin, active oxygen is generated inside and outside epidermal cells, so that abnormal cell activities are caused, and the skin aging is promoted. Repeated sunburn with UVB may cause a decrease in skin immunity, resulting in the development of skin cancer. Studies have shown that UVB irradiation is an important environmental factor in the development of skin cancer.

The after-sun soothing repair is mainly carried out from the following aspects: firstly, the skin needs to be relieved, the skin microcirculation is promoted, and the skin irritation is reduced, so that the symptoms of skin redness, fever, allergy, inflammation and the like are relieved, secondly, a large amount of water is needed to be supplemented, damaged cells are moistened, skin channels are opened again, the barrier function is repaired, and a large amount of free radicals generated by ultraviolet irradiation and excessive secretion of melanin need to be resisted.

Therefore, the key to overcoming various skin problems after the sun shines is the after-sun soothing repair, the after-sun time is 6-8 hours, and the after-sun repair product can be reasonably and effectively used for quickly relieving the after-sun problems of the skin.

Disclosure of Invention

In view of this, the technical problem to be solved by the present invention is to provide an after-sun soothing and repairing composition and an application thereof, wherein the after-sun soothing and repairing composition not only can soothe skin and play a role of calming skin, but also can effectively moisturize skin, and effectively improve symptoms of skin redness, prickling, itching and the like after being sun-cured.

The invention provides a post-basking soothing and repairing composition, which comprises:

preferably, the average molecular weight of the DNA sodium is 4 to 26 ten thousand daltons.

Preferably, the plankton extract is selected from one or more of artemia extract, chlorella extract, spirulina maxima extract and porphyridium extract.

Preferably, the method comprises the following steps:

the invention also provides a skin care product which comprises the after-sun soothing and repairing composition.

Preferably, the quality of the after-sun soothing and repairing composition is 0.01-3% of the quality of the skin care product.

The invention also provides an after-sun soothing repair cream which comprises the after-sun soothing repair composition.

Preferably, the mass of the after-sun soothing and repairing composition is 0.1-5% of that of the after-sun soothing and repairing cream;

the after-sun soothing and repairing cream also comprises a humectant, a chelating agent, a thickening agent, an emulsifier and grease;

the mass of the humectant is 4-8% of that of the after-sun soothing and repairing cream;

the mass of the chelating agent is 0.03-0.1% of that of the after-sun soothing repair cream;

the mass of the thickening agent is 2.5-4% of that of the after-sun soothing and repairing cream;

the mass of the emulsifier is 3-5% of that of the after-sun soothing and repairing cream;

the mass of the grease is 8-10% of the mass of the after-sun soothing and repairing cream.

Preferably, the humectant is selected from one or more of glycerin, butylene glycol, caprylyl glycol, betaine, hyaluronic acid and sodium hyaluronate;

the chelating agent is selected from disodium ethylene diamine tetraacetate;

the thickening agent is selected from one or more of xanthan gum, polyacrylate, carbomer, acryloyl dimethyl ammonium taurate/VP copolymer, acryloyl dimethyl ammonium taurate/behenyl polyether-25 methacrylate cross-linked polymer and polyacryl dimethyl sodium taurate;

the emulsifier is selected from one or more of polysorbate-20, sodium acrylate/lecithin, cetearyl alcohol/cetearyl glucoside, cetearyl alcohol and glyceryl stearate/PEG-100 stearate;

the grease is selected from one or more of dioctyl carbonate, isononyl isononanoate, hemp seed oil, mango seed fat, jojoba seed oil, shea butter, butylated hydroxytoluene, hydrogenated polyisobutene, cetyl ethylhexanoate and polydimethylsiloxane.

The invention also provides a preparation method of the after-sun soothing and repairing cream, which comprises the following steps:

s1) mixing water, a humectant, a chelating agent and a thickening agent to obtain a phase A;

mixing an emulsifier with grease to obtain a phase B;

and S2) respectively heating the phase A and the phase B, adding the phase B into the phase A for homogenization, cooling, and adding the after-sun soothing and repairing composition to obtain the after-sun soothing and repairing cream.

The invention provides a post-basking soothing and repairing composition, which comprises: 0.5 to 3 parts by weight of DNA sodium; 0.4 to 1.5 parts by weight of plankton extract; 0.1 to 0.5 weight portion of resveratrol; 1 to 20 portions of ectoin. Compared with the prior art, the composition provided by the invention has the advantages that through mutual cooperation of the components, the skin can be relieved, the skin calming effect is realized, the effective water replenishing is realized on the skin, the symptoms of redness, stabbing pain, itching and the like after the skin is exposed to the sun are effectively improved, meanwhile, free radicals generated by ultraviolet irradiation can be timely eliminated, the generation of melanin is inhibited, and the skin is helped to recover health.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.

The invention provides a post-basking soothing and repairing composition comprising:

wherein, the raw material of the DNA sodium is selected from deep-sea salmon milt from pollution-free zones in the North Pacific ocean, the maturation degree of the milt is high, and the content of DNA nucleic acid is rich. In the present invention, the average molecular weight of the DNA sodium is preferably 4 to 26 ten thousand daltons; the content of the DNA sodium in the after-sun soothing and repairing composition is preferably 1 to 3 parts by weight; in the examples provided herein, the DNA sodium is specifically present in the post-basking soothing and repairing composition in an amount of 0.5 parts by weight, 0.6 parts by weight, 0.8 parts by weight, 1 part by weight, 1.5 parts by weight, 2 parts by weight, or 3 parts by weight.

The plankton extract is derived from plankton. Plankton refers to an animal or a plant that is living on the water surface because it has no ability to move or is very weak in the living body in the water areas such as the sea, lake, and river, and thus cannot move against the water flow. Plankton is diverse, especially animals, and almost all zooplankton groups are visible: small protozoa, algae, bacteria, but also larvae of certain crustaceans, mollusks and certain animals. In the present invention, the plankton extract may be one or more of artemia extract, chlorella extract, spirulina maxima extract and porphyridium extract, and more preferably chlorella extract. In the examples provided herein, the plankton extract is specifically present in the post-basking soothing repair composition in an amount of 0.4 parts by weight, 0.5 parts by weight, 0.6 parts by weight, 0.8 parts by weight, 1 part by weight, 1.2 parts by weight, or 1.5 parts by weight.

Resveratrol is a natural plant polyphenol, and is present in various plants, such as grape, blueberry, mulberry, giant knotweed, and the like; the chemical structure of resveratrol is similar to human estrogen, and can relieve inflammation symptoms such as skin edema after exposure to ultraviolet rays, and avoid skin aging. In embodiments provided herein, the resveratrol is specifically included in the post-basking soothing and rejuvenating composition in an amount of 0.1 parts by weight, 0.15 parts by weight, 0.2 parts by weight, 0.25 parts by weight, 0.3 parts by weight, 0.35 parts by weight, 0.4 parts by weight, 0.45 parts by weight, or 0.5 parts by weight.

Ectoin, namely tetrahydromethyl pyrimidine carboxylic acid, is an important substance for maintaining osmotic pressure balance, and the unique molecular structure of the ectoin makes the ectoin have strong water molecule complexing ability. The ectoin can be used as a stabilizer to protect enzyme, DNA, cells and the like from adverse environments such as high salinity, drying, freezing, high temperature and the like, and has the effects of stress resistance assistance and the like. The skin care moisturizer is an excellent moisturizer for skin, can improve the immune protection capability of skin cells, increase the cell repair capability, effectively resist the invasion of microorganisms and allergens, play the roles of anti-allergy, anti-inflammation, repair and protection and strengthen the micro-ecological barrier. In the examples provided by the present invention, the content of ectoin in the after-sun soothing and repairing composition is specifically 1 part by weight, 2 parts by weight, 3 parts by weight, 4 parts by weight, 5 parts by weight, 6 parts by weight, 7 parts by weight, 8 parts by weight, 9 parts by weight, 10 parts by weight, 11 parts by weight, 12 parts by weight, 13 parts by weight, 14 parts by weight, 15 parts by weight, 16 parts by weight, 16.5 parts by weight, 17 parts by weight, 17.75 parts by weight, 18 parts by weight, 19 parts by weight, or 20 parts by weight.

In the present invention, preferably, the after-sun soothing and repairing composition comprises:

further preferably, the after-sun soothing repair composition comprises:

alternatively, the post-basking soothing repair composition comprises:

alternatively, the post-basking soothing repair composition comprises:

alternatively, the post-basking soothing repair composition comprises:

alternatively, the post-basking soothing repair composition comprises:

the composition provided by the invention can help each substance in the composition to better exert the effects through mutual cooperation of all the components, further improve the effects of antioxidation, after-sun moisture retention, repair and the like of the composition, so that the composition can relieve the skin, play a role in calming the skin, effectively supplement water for the skin, effectively improve the symptoms of redness, stabbing pain, itching and the like of the skin after sun exposure, and can timely clear free radicals generated by ultraviolet irradiation, inhibit the generation of melanin and help the skin to recover health.

The invention also provides an application of the after-sun soothing and repairing composition in a skin care product.

Such applications include, but are not limited to, the addition of the compositions provided herein with after-sun soothing treatments to skin care products, use in direct combination with skin care products, use in indirect combination with other skin care products.

The skin care products include, but are not limited to, water, milk, cream, essence, sunscreen cream, oils, body refreshing products, bath products, eye skin care products, facial masks, face washing products, makeup removing products, foundation products, pressed powder products, poplites, body painting cosmetics, eyebrow pencils, eye shadows, eyelids, eye hairs, eye color makeup remover, lip protecting creams, lip gloss oils, common lip creams and lip line pens.

The quality of the after-sun soothing and repairing composition is preferably 0.01-3% of that of the skin care product;

The mass of the after-sun soothing and repairing composition is preferably 0.01-3% of that of the after-sun soothing and repairing cream; in the present invention, the after-sun soothing and repairing composition in the after-sun soothing and repairing cream may specifically be 0.01%, 0.03%, 0.05%, 0.08%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.5%, 2%, 2.5%, 3% by mass.

In the invention, the after-sun soothing and repairing cream further comprises a humectant, a chelating agent, a thickener, an emulsifier and grease.

The mass of the humectant is preferably 4-8%, more preferably 4-7% and even more preferably 5-6% of the mass of the after-sun soothing and repairing cream; the humectant is well known to those skilled in the art, and is not particularly limited, and in the present invention, one or more of glycerin, butylene glycol, caprylyl glycol, betaine, hyaluronic acid, and sodium hyaluronate are preferred, and glycerin, butylene glycol, and sodium hyaluronate are more preferred; the mass ratio of the glycerin, the butanediol and the sodium hyaluronate is preferably (1-5): (1-5): 0.1, more preferably (2 to 4): (2-4): 0.1, more preferably (2.5 to 3.5): (2-3): 0.1, most preferably 2.9:2:0.1.

the mass of the chelating agent is preferably 0.03-0.1%, more preferably 0.03-0.08%, still more preferably 0.04-0.06%, and most preferably 0.05% of the mass of the after-sun soothing and repairing cream; the chelating agent is not particularly limited as long as it is a chelating agent well known to those skilled in the art, and disodium edetate is preferable in the present invention.

The mass of the thickener is preferably 2.5-4%, more preferably 2.5-3.5% and even more preferably 3% of the mass of the after-sun soothing and repairing cream; the thickener is a thickener known to those skilled in the art, and is not particularly limited, and in the present invention, one or more of xanthan gum, polyacrylate, carbomer, acryloyl dimethyl taurate/VP copolymer, acryloyl dimethyl taurate/behenyl polyether-25 methacrylate cross-linked polymer, and polyacryl dimethyl taurate are preferable.

The mass of the emulsifier is preferably 3-5%, more preferably 4-5%, and even more preferably 4.5% of the mass of the after-sun soothing and repairing cream; the emulsifier is well known to those skilled in the art, and is not particularly limited, and in the present invention, one or more of polysorbate-20, sodium/lecithin (acrylate copolymer), cetearyl alcohol/cetearyl glucoside, cetearyl alcohol and glyceryl stearate/PEG-100 stearate are preferred; in the examples provided by the present invention, the emulsifiers polysorbate-20, cetearyl/cetearyl glucoside and cetearyl alcohol are specifically exemplified, and the mass ratio of polysorbate-20, cetearyl/cetearyl glucoside and cetearyl alcohol is preferably 1: (2-4): (4 to 6), more preferably 1: (2.5-3.5): (4.5 to 5.5), and more preferably 1:3:5.

the mass of the grease is preferably 8-10%, more preferably 9-10%, and even more preferably 9.5% of the mass of the after-sun soothing and repairing cream; the oil is well known to those skilled in the art, and is not particularly limited, and in the present invention, one or more of dioctyl carbonate, isononyl isononanoate, hemp seed oil, mango seed fat, jojoba seed oil, shea butter, butylated hydroxytoluene, hydrogenated polyisobutene, cetyl ethylhexanoate, and polydimethylsiloxane are preferable; in the examples provided by the present invention, the grease is specifically exemplified by isononyl isononanoate, dioctyl carbonate, jojoba seed oil and cetyl ethyl hexanoate; the mass ratio of isononyl isononanoate, dioctyl carbonate, jojoba seed oil to cetyl ethylhexanoate is preferably (2-4): (3-5): 1: (1-2), more preferably (2.5-3.5): (3.5-4.5): 1: (1-2), more preferably 3:4:1:1.5.

in addition to the above components, the after-sun soothing cream preferably further comprises water.

The after-sun soothing and repairing composition provided by the invention has the advantages that the formula is mild, the proportion is optimized, the synergistic effect is realized, the matching and enhancing effects of all components are realized, the irritation is avoided, the most obvious after-sun soothing and repairing effect is realized under the combined action of other effective components, the after-sun instantaneous repairing effect of the skin care product is obvious, the market potential is great, the preparation method is simple, and the after-sun soothing and repairing composition can be applied to large-scale production.

The invention also provides a preparation method of the after-sun soothing and repairing cream, which comprises the following steps: s1) mixing water, a humectant, a chelating agent and a thickening agent to obtain a phase A; mixing an emulsifier with grease to obtain a phase B; and S2) respectively heating the phase A and the phase B, adding the phase B into the phase A for homogenizing, cooling, and adding the after-sun soothing and repairing composition to obtain the after-sun soothing and repairing cream.

Wherein, the sources of all raw materials are not specially limited and can be sold in the market; the type and content of the after-sun soothing and repairing composition, the humectant, the chelating agent, the thickener, the emulsifier and the oil are the same as those described above, and are not described again.

Mixing water, humectant, chelating agent and thickener to obtain phase A; mixing emulsifier with oil to obtain phase B.

Respectively heating the phase A and the phase B; preferably to 70 ℃ to 80 ℃ respectively.

Adding the phase B into the phase A for homogenization; the rotation speed of the homogenization is preferably 12000-15000 r/min; the time for homogenization is preferably 3 to 5min.

Homogenizing, cooling, and adding the above after-sun soothing and repairing composition; the cooling temperature is preferably 40-45 ℃; adding the after-sun soothing and repairing composition and preferably stirring; the rotating speed of the stirring is preferably 500-800 r/min; the stirring time is preferably 20 to 30min.

And finally, preferably cooling to room temperature to obtain the after-sun soothing repair cream.

To further illustrate the present invention, a post-basking soothing and repairing composition and its use, provided by the present invention, are described in detail below with reference to the examples.

The reagents used in the following examples are all commercially available.

The DNA-sodium is from Shanghai Huiwen company, and the commodity model is DNA-sodium;

the plankton extract is from SYMRISE, and is SYMCONTROL CARE;

the sodium polyacrylate is from Nikkaido, and the commercial model is COVACRYL AC;

polysorbate-20 is from Bisheng, and is available under the trade name SP TWEEN 20MBAL-LQ- (SG);

cetearyl alcohol/cetearyl glucoside is from Boehringer, model MONTANOV68MB;

JOJOBA seed OIL is from sanderi and has a commercial model of JOJOBA OIL PRESSED.

Example 1

This example provides a composition with after-sun soothing and repairing effects, wherein the composition comprises, by weight, 0.5 parts of sodium DNA, 0.4 parts of plankton extract, 0.1 parts of resveratrol, and 20 parts of ectoin.

Example 2

This example provides a composition with after-sun soothing and repairing effects, wherein the composition includes, by weight, 3 parts of DNA sodium, 1 part of plankton extract, 0.5 part of resveratrol, and 16.5 parts of ectoin.

Example 3

This example provides a composition with after-sun soothing and repairing effects, wherein the composition includes, by weight, 1.5 parts of DNA sodium, 1.5 parts of plankton extract, 0.25 part of resveratrol, and 17.75 parts of ectoin.

Example 4

The embodiment provides a composition with after-sun soothing and repairing functions, wherein the composition comprises 2 parts by weight of DNA sodium, 1.5 parts by weight of plankton extract, 0.5 part by weight of resveratrol and 10 parts by weight of ectoin.

Example 5

This example provides a composition with after-sun soothing and repairing functions, wherein the composition comprises, by weight, 3 parts of DNA sodium, 1.5 parts of plankton extract, 0.5 part of resveratrol, and 1 part of ectoin.

Comparative example 1

This comparative example provides a composition which differs from the formulation of example 1 only in that it does not contain DNA sodium, and the amount of reduction is increased proportionally to the mass ratio of plankton extract, resveratrol, ectoine over these four components.

Comparative example 2

This comparative example provides a composition which differs from the formulation of example 1 only in that it does not contain a plankton extract, the amount of reduction being increased proportionally to the mass ratio of sodium DNA, resveratrol, ectoin over these four components.

Comparative example 3

This comparative example provides a composition which differs from the formulation of example 1 only in that it does not contain resveratrol, the amount of which is reduced being increased proportionally to the mass ratio of sodium DNA, plankton extract, ectoine over these four components.

Comparative example 4

This comparative example provides a composition which differs from the formulation of example 1 only in that it does not contain ectoin, and the amount of reduction is increased proportionally to the mass ratio of sodium DNA, plankton extract, resveratrol over these four components.

Comparative examples 5 to 8

Comparative examples 5 to 8 provide a single material.

Comparative example 9

This comparative example provides a composition which, in comparison with example 1, consists in replacing resveratrol by astaxanthin, the remainder being unchanged.

Comparative example 10

This comparative example provides a composition which, in comparison with example 1, consists in replacing the plankton extract with retinol, the remaining substances remaining unchanged.

Application example 1 after-sun soothing repair cream

The preparation method comprises the following steps:

respectively heating phase A and phase B to 75 ℃, adding phase B into phase A, homogenizing at a homogenizing speed of 15000r/min for 3min, cooling to 45 ℃, adding phase C, stirring at a rotating speed of 500r/min for 30min, and cooling to room temperature to obtain the after-sun soothing and repairing cream.

Application examples 2 to 5

The "after-sun soothing and repairing composition 1% obtained in example 1" in application example 1 was replaced with "after-sun soothing and repairing composition 1% obtained in examples 2 to 5 of the present invention", respectively, and the other components and contents were the same as those in application example 1.

Comparative examples 1 to 8 of application

The composition 1% obtained in example 1 above was replaced with "composition 1% obtained in comparative examples 1 to 8" respectively, and the other components and contents were the same as those in example 1.

Comparative application examples 9 to 10

The composition 1% obtained in example 1 above was replaced with "composition 1% obtained in comparative examples 9 to 10" respectively, and the other components and contents were the same as those in example 1.

Comparative application example 11

In the application comparative example, the after-sun soothing and repairing composition prepared in the embodiment is not added, the reduced amount is complemented with water, and other components and contents are the same as those in application example 1.

In order to better illustrate the advantages of the present invention, the experimental effects of the technical solution provided by the present invention are given below:

test 1: safety test

The test substance: the after-sun soothing repair cream base of application examples 1-5 and application comparative examples 1-11.

The test method comprises the following steps: a qualified spot test device is selected, a skin closed type spot test method is adopted, about 0.020mL of a test object is placed in a spot test device chamber, and a control hole is a blank control (no substance is placed). The spot test device with the test substance is applied to the back or the forearm curve of the subject with hypoallergenic tape, and is applied to the skin uniformly by pressing with the palm for 24h.

The skin reactions were observed according to the standard of table 1 30min (after disappearance of the indentation), 24h and 48h after removal of the test article plaque test device, respectively, and the observation results were recorded.

TABLE 1 skin Enclosed Patch test skin response grading Standard

And (4) conclusion: according to the skin reaction grading standard of the skin closed patch test in the technical Specification for cosmetic safety (2015 edition), the results of the human skin patch test of the test object application examples 1-5 and the application comparative examples 1-11 show that: all of the skin of 30 subjects showed negative reactions (rating scale: 0).

And (3) testing 2: water replenishment repair test

1) Test samples: the after-sun soothing repair creams of application examples 1-5 and comparative examples 1-11 were applied.

2) The test method comprises the following steps: 80 volunteers of 20-45 years old are selected as trial objects, 70 volunteers are randomly divided into 14 groups, 5 volunteers in each group, and the skin of the test subject is healthy and meets the selection standard. 3 days before detection, no cosmetics are applied to the face, an appropriate amount of after-sun soothing cream is applied to the face skin by each group of test subjects, the after-sun soothing cream is used once every morning and evening and is continuously used for 4 weeks, a skin tester (Cutomer dual MPA 580) is used for detecting the water content of the skin and the skin percutaneous water loss rate at 0 week and 4 week, the detection is repeated for 5 times respectively to obtain an average value, and the water content of the skin and the percutaneous water loss condition of the skin before and after the after-sun soothing cream is used are evaluated. The results are shown in Table 2.

Table 2 moisturizing functional test

TABLE 3 percutaneous Water loss (TEWL)

Sample (I)	Week 0 TEWL level	Week 4 TEWL content	Rate of change
				Application example 1	27.16	14.84	-45.36％
Application example 2	25.95	14.23	-45.16％
				Application example 3	23.94	13.18	-44.95％
Application example 4	24.92	14.52	-41.73％
				Application example 5	23.81	14.06	-40.95％
Application comparative example 1	28.64	21.19	-26.01％
				Comparative application example 2	26.34	20.11	-23.65％
Comparative application example 3	25.84	18.64	-27.86％
				Comparative application example 4	27.64	20.68	-25.18％
Comparative application example 5	23.58	20.73	-12.09％
				Comparative application example 6	24.23	21.34	-11.93％
Application comparative example 7	25.31	21.67	-14.38％
				Comparative application example 8	26.83	22.54	-15.99％
Comparative application 9	24.65	16.37	-33.59％
				Comparative application example 10	25.76	16.51	-35.91％
Comparative application example 11	27.64	26.05	-5.75％

From the experimental results in table 2, it can be seen that the after-sun soothing cream using the application example of the invention can significantly improve the moisture content of the skin, the increase rate of the moisture content of the skin at 4 weeks of the after-sun soothing cream using the application examples 1-5 continuously can reach more than 35%, while the increase range of the moisture content of the skin using the after-sun soothing cream using the application comparative example is smaller; the experimental results in table 3 show that the continuous use of the after-sun soothing and repairing cream of application examples 1 to 5 has a transdermal moisture change rate of 40% or more for 4 weeks, while the change of the application comparative example is small, which indicates that the components in the composition of the present invention have a synergistic effect, and the components in the composition of the present invention can have good moisturizing effect by scientific compounding, provide moisture for dry skin cells, and enhance the skin barrier. Compared with application comparative examples 9-10, the moisturizing and repairing effects of application example 1 are better, which shows that better synergistic effects can be achieved only under the interaction of the four substances.

Test example 3: test for antioxidant efficacy

1) Test samples: deionized water for the after-sun soothing cream of application examples 1 to 5 and application comparative examples 1 to 11 was prepared into 4% aqueous solutions as test samples, respectively.

2) The test method comprises the following steps:

hydroxyl radical scavenging experiment: taking 0.5mL of absolute ethanol solution of o-diazaphenanthrene with the concentration of 0.75mmol/L into a test tube with a plug, respectively adding 2mL and 1mL of phosphate buffer solution with the pH of 7.4 and the concentration of 0.2mol/L into the test tube, fully and uniformly mixing the test samples, and adding 0.5mL of FeSO with the concentration of 0.75mmol/L into the test tube ₄ ·7H ₂ O solution, mixed again and then added with 0.5mL of 0.01% (v/v) H ₂ O ₂ After being put in a constant-temperature water bath at 37 ℃ for 60min, the absorbance values of the mixed solutions of each group are respectively measured at 536nm and recorded As As, and distilled water is used As air instead of a sample solutionWhite group absorbance value, recorded as Ab, and distilled water instead of H ₂ O ₂ And measuring the absorbance value An of the damage group, and calculating the hydroxyl radical clearance of the test sample according to the following formula: hydroxyl radical clearance (%) = [ (As-An)/(Ab-An)]X 100%, the average of three measurements was taken. The test results are shown in table 4.

DPPH free radical scavenging experiments: taking 3mL of DPPH-absolute ethyl alcohol solution with the concentration of 0.2mmol/L, putting the DPPH-absolute ethyl alcohol solution into a cuvette, adding 1mL of test sample, uniformly mixing, keeping out of the sun for 30min at room temperature, measuring the absorbance at the wavelength of 517nm, and marking the absorbance value as A1, adding 3mL of absolute ethyl alcohol solution and 1mL of test sample solution, and marking the absorbance value as A2, adding 3mL of DPPH-absolute ethyl alcohol solution and 1mL of absolute ethyl alcohol solution, and marking the absorbance value as A3. The DPPH radical clearance was calculated as follows: DPPH radical clearance (%) = [1- (A1-A2)/A3 ] × 100%, and the average of three measurements was taken. The results are shown in Table 4.

TABLE 4 antioxidant efficacy test results

From the experimental results in table 4, it can be seen that the after-sun soothing and repairing composition added in the application example of the present invention has a strong scavenging ability for hydroxyl radicals and DPPH radicals, while the composition added in the application comparative example has a weak scavenging ability for radicals, which indicates that the after-sun soothing and repairing composition of the present invention can effectively resist the activity of radicals and has a good antioxidant effect.

Test example 4: evaluation on trial product

1. The tested samples were: the tested samples are the after-sun soothing repair cream obtained in the application examples 1-5 and the after-sun soothing repair cream obtained in the application comparative examples 1-11.

2. The test method comprises the following steps: randomly selecting 80 female normal volunteers without skin allergy history, averagely dividing the volunteers into 16 groups, distributing 14 corresponding groups of after-sun soothing cream for each group of 5 women according to a normal sequence, selecting summer Qiyue as a test time, using the after-sun soothing cream for one month, particularly using the after-sun soothing cream after sun, using the after-sun soothing cream once in the morning and evening every day, and finally evaluating the using effect of the after-sun soothing cream for each group, wherein the scoring standard is as follows: the score is 0-10 as standard, and is divided into five grades, so the using effect is good: 9-10 minutes; preferably: 8-9 minutes; generally 7 to 8 minutes; poor: 5-6 minutes; difference: 3 to 4 minutes.

3. The evaluation indexes include final after-sun blushing repairing effect, relieving effect, moisturizing effect, absorption effect, after-sun calming effect and skin brightening effect.

4. The effect score after one month was used and the results are shown in table 5.

TABLE 5 test results of the products

As can be seen from Table 5, the overall after-sun soothing and repairing effect of the products of application examples 1-5 of the present application is significantly improved compared with that of application comparative examples 1-11, which shows that the combination of the four substances of the present invention has a synergistic promoting effect on the after-sun repairing effect.

Claims

1. A post-basking soothing repair composition comprising:

2. the sunless soothing conditioner composition of claim 1, wherein said DNA sodium has an average molecular weight of from 4 to 26 ten thousand daltons.

3. The sunless soothing restorative composition of claim 1, wherein the plankton extract is selected from one or more of artemia extract, chlorella extract, spirulina maxima extract, and porphyridium extract.

4. The sunless soothing restorative composition of claim 1, comprising:

5. a skin care product comprising the after-sun soothing repair composition of any one of claims 1 to 4.

6. The skin care product of claim 5, wherein the after-sun soothing and rejuvenating composition is present in an amount of from 0.01% to 3% by weight of the skin care product.

7. A post-basking soothing cream comprising the post-basking soothing cream of any one of claims 1-4.

8. The after-sun soothing repair cream of claim 7, wherein the mass of the after-sun soothing repair composition is 0.1% to 5% of the mass of the after-sun soothing repair cream;

9. The sunless soothing cream of claim 8, wherein the moisturizer is selected from the group consisting of glycerin, butylene glycol, caprylyl glycol, betaine, hyaluronic acid, and sodium hyaluronate;

the chelating agent is selected from disodium ethylene diamine tetraacetate;

10. A preparation method of the after-sun soothing repair cream is characterized by comprising the following steps:

mixing an emulsifier with grease to obtain a phase B;

s2) respectively heating the phase A and the phase B, adding the phase B into the phase A for homogenization, cooling, and adding the after-sun soothing and repairing composition of any one of claims 1 to 4 to obtain the after-sun soothing and repairing cream.