CN115361879A - 牛奶外泌体产品和方法、营养组合物和治疗方法 - Google Patents

牛奶外泌体产品和方法、营养组合物和治疗方法 Download PDF

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Publication number
CN115361879A
CN115361879A CN202180027612.8A CN202180027612A CN115361879A CN 115361879 A CN115361879 A CN 115361879A CN 202180027612 A CN202180027612 A CN 202180027612A CN 115361879 A CN115361879 A CN 115361879A
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China
Prior art keywords
exosome
whey
milk
exosomes
fraction
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Pending
Application number
CN202180027612.8A
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English (en)
Chinese (zh)
Inventor
J·M·洛佩兹佩德罗萨
R·鲁埃达卡布雷拉
J·加西亚马丁内斯
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Abbott Laboratories
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Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CN115361879A publication Critical patent/CN115361879A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1425—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/15—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins
    • A23C9/1512—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins containing isolated milk or whey proteins, caseinates or cheese; Enrichment of milk products with milk proteins in isolated or concentrated form, e.g. ultrafiltration retentate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1276—Globules of milk; Constituents thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pediatric Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Water Supply & Treatment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN202180027612.8A 2020-04-03 2021-04-01 牛奶外泌体产品和方法、营养组合物和治疗方法 Pending CN115361879A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20382267 2020-04-03
EP20382267 2020-04-03
EP20382934 2020-10-27
EP20382934 2020-10-27
PCT/US2021/025300 WO2021202824A1 (en) 2020-04-03 2021-04-01 Bovine milk exosome products and methods, nutritional compositions, and therapeutic methods

Publications (1)

Publication Number Publication Date
CN115361879A true CN115361879A (zh) 2022-11-18

Family

ID=75540090

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180027612.8A Pending CN115361879A (zh) 2020-04-03 2021-04-01 牛奶外泌体产品和方法、营养组合物和治疗方法

Country Status (8)

Country Link
US (1) US20230263178A1 (enExample)
EP (1) EP4125439A1 (enExample)
JP (1) JP2023520790A (enExample)
CN (1) CN115361879A (enExample)
CA (1) CA3172602A1 (enExample)
IL (1) IL296959A (enExample)
MX (1) MX2022011968A (enExample)
WO (1) WO2021202824A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113993526A (zh) * 2019-06-13 2022-01-28 忠北大学校产学协力团 包含源自牛奶的外泌体作为有效成分的用于治疗代谢性疾病的药物组合物
CN120859158A (zh) * 2025-09-28 2025-10-31 四平君乐宝乳业有限公司 一种调节睡眠的营养组合物及其制备方法和应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023076144A1 (en) * 2021-10-29 2023-05-04 Abbott Laboratories Methods and compositions for improving insulin production and secretion
WO2024015441A1 (en) * 2022-07-13 2024-01-18 Abbott Laboratories Bovine milk exosomes for delivering vitamin k2 and increasing bioavailability
ES2977833A1 (es) 2023-01-17 2024-08-30 Univ Madrid Autonoma Procedimiento para la obtención de exosomas a partir de mazada, exosomas obtenidos y aplicaciones de los mismos
CN120936250A (zh) 2023-03-29 2025-11-11 菲仕兰坎皮纳荷兰公司 包含乳细胞外囊泡和半乳糖的组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014134132A1 (en) * 2013-02-26 2014-09-04 University Of Louisville Research Foundation, Inc. Milk-derived microvesicle compositions and related methods
WO2016033695A1 (en) * 2014-09-05 2016-03-10 Exerkine Corporation Exosome isolation
JP6349405B2 (ja) * 2014-09-09 2018-06-27 森永乳業株式会社 抗炎症剤
US10874114B2 (en) * 2015-11-29 2020-12-29 Hadasit Medical Research Services And Development Ltd. Supplementation of milk formulas with microvesicles isolated from milk
AU2019297344A1 (en) * 2018-07-02 2021-01-28 Puretech Lyt, Inc. Milk vesicles for use in delivering biological agents
JP7769607B2 (ja) * 2019-11-08 2025-11-13 アボット・ラボラトリーズ ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113993526A (zh) * 2019-06-13 2022-01-28 忠北大学校产学协力团 包含源自牛奶的外泌体作为有效成分的用于治疗代谢性疾病的药物组合物
CN113993526B (zh) * 2019-06-13 2024-06-18 忠北大学校产学协力团 包含源自牛奶的外泌体作为有效成分的用于治疗代谢性疾病的药物组合物
CN120859158A (zh) * 2025-09-28 2025-10-31 四平君乐宝乳业有限公司 一种调节睡眠的营养组合物及其制备方法和应用
CN120859158B (zh) * 2025-09-28 2026-03-06 四平君乐宝乳业有限公司 一种调节睡眠的营养组合物及其制备方法和应用

Also Published As

Publication number Publication date
IL296959A (en) 2022-12-01
EP4125439A1 (en) 2023-02-08
WO2021202824A1 (en) 2021-10-07
JP2023520790A (ja) 2023-05-19
US20230263178A1 (en) 2023-08-24
CA3172602A1 (en) 2021-10-07
MX2022011968A (es) 2022-10-20

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PB01 Publication
PB01 Publication
CB02 Change of applicant information
CB02 Change of applicant information

Address after: Illinois, America

Applicant after: ABBOTT LABORATORIES

Address before: Illinois, USA

Applicant before: ABBOTT LABORATORIES

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20221118