JP2023520790A - ウシ乳エキソソーム生成物および方法、栄養組成物、ならびに治療方法 - Google Patents

ウシ乳エキソソーム生成物および方法、栄養組成物、ならびに治療方法 Download PDF

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Publication number
JP2023520790A
JP2023520790A JP2022559964A JP2022559964A JP2023520790A JP 2023520790 A JP2023520790 A JP 2023520790A JP 2022559964 A JP2022559964 A JP 2022559964A JP 2022559964 A JP2022559964 A JP 2022559964A JP 2023520790 A JP2023520790 A JP 2023520790A
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Japan
Prior art keywords
exosome
whey
exosomes
enriched product
fraction
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Pending
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JP2022559964A
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English (en)
Japanese (ja)
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JP2023520790A5 (enExample
Inventor
ペドロサ，ジョゼ マリア ロペス
カブレラ，リカルド ルエダ
マルティネス，ジョージ ガルシア
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Abbott Laboratories
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Abbott Laboratories
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Application filed by Abbott Laboratories filed Critical Abbott Laboratories
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Publication of JP2023520790A5 publication Critical patent/JP2023520790A5/ja
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1425—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/15—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins
    • A23C9/1512—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins containing isolated milk or whey proteins, caseinates or cheese; Enrichment of milk products with milk proteins in isolated or concentrated form, e.g. ultrafiltration retentate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1276—Globules of milk; Constituents thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pediatric Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Water Supply & Treatment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2022559964A 2020-04-03 2021-04-01 ウシ乳エキソソーム生成物および方法、栄養組成物、ならびに治療方法 Pending JP2023520790A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20382267 2020-04-03
EP20382267 2020-04-03
EP20382934 2020-10-27
EP20382934 2020-10-27
PCT/US2021/025300 WO2021202824A1 (en) 2020-04-03 2021-04-01 Bovine milk exosome products and methods, nutritional compositions, and therapeutic methods

Publications (2)

Publication Number Publication Date
JP2023520790A true JP2023520790A (ja) 2023-05-19
JP2023520790A5 JP2023520790A5 (enExample) 2024-04-10

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JP2022559964A Pending JP2023520790A (ja) 2020-04-03 2021-04-01 ウシ乳エキソソーム生成物および方法、栄養組成物、ならびに治療方法

Country Status (8)

Country Link
US (1) US20230263178A1 (enExample)
EP (1) EP4125439A1 (enExample)
JP (1) JP2023520790A (enExample)
CN (1) CN115361879A (enExample)
CA (1) CA3172602A1 (enExample)
IL (1) IL296959A (enExample)
MX (1) MX2022011968A (enExample)
WO (1) WO2021202824A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102223138B1 (ko) * 2019-06-13 2021-03-04 충북대학교 산학협력단 우유로부터 유래된 엑소좀을 유효성분으로 포함하는 대사성 질환 치료용 약학적 조성물
WO2023076144A1 (en) * 2021-10-29 2023-05-04 Abbott Laboratories Methods and compositions for improving insulin production and secretion
WO2024015441A1 (en) * 2022-07-13 2024-01-18 Abbott Laboratories Bovine milk exosomes for delivering vitamin k2 and increasing bioavailability
ES2977833A1 (es) 2023-01-17 2024-08-30 Univ Madrid Autonoma Procedimiento para la obtención de exosomas a partir de mazada, exosomas obtenidos y aplicaciones de los mismos
CN120936250A (zh) 2023-03-29 2025-11-11 菲仕兰坎皮纳荷兰公司 包含乳细胞外囊泡和半乳糖的组合物
CN120859158B (zh) * 2025-09-28 2026-03-06 四平君乐宝乳业有限公司 一种调节睡眠的营养组合物及其制备方法和应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014134132A1 (en) * 2013-02-26 2014-09-04 University Of Louisville Research Foundation, Inc. Milk-derived microvesicle compositions and related methods
WO2016039356A1 (ja) * 2014-09-09 2016-03-17 森永乳業株式会社 抗炎症剤
WO2017090049A1 (en) * 2015-11-29 2017-06-01 Hadasit Medical Research Services And Development Ltd. Supplementation of milk formulas with microvesicles isolated from milk
US20170296627A1 (en) * 2014-09-05 2017-10-19 Exerkine Corporation Exersomes, methods of producing and method of using
WO2020010161A1 (en) * 2018-07-02 2020-01-09 Pure Tech Health Llc Milk vesicles for use in delivering biological agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7769607B2 (ja) * 2019-11-08 2025-11-13 アボット・ラボラトリーズ ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014134132A1 (en) * 2013-02-26 2014-09-04 University Of Louisville Research Foundation, Inc. Milk-derived microvesicle compositions and related methods
US20170296627A1 (en) * 2014-09-05 2017-10-19 Exerkine Corporation Exersomes, methods of producing and method of using
WO2016039356A1 (ja) * 2014-09-09 2016-03-17 森永乳業株式会社 抗炎症剤
WO2017090049A1 (en) * 2015-11-29 2017-06-01 Hadasit Medical Research Services And Development Ltd. Supplementation of milk formulas with microvesicles isolated from milk
WO2020010161A1 (en) * 2018-07-02 2020-01-09 Pure Tech Health Llc Milk vesicles for use in delivering biological agents

Also Published As

Publication number Publication date
IL296959A (en) 2022-12-01
EP4125439A1 (en) 2023-02-08
WO2021202824A1 (en) 2021-10-07
US20230263178A1 (en) 2023-08-24
CA3172602A1 (en) 2021-10-07
MX2022011968A (es) 2022-10-20
CN115361879A (zh) 2022-11-18

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