CN115337972B - Split type ultrafiltration centrifuging tube device - Google Patents
Split type ultrafiltration centrifuging tube device Download PDFInfo
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- CN115337972B CN115337972B CN202211276869.XA CN202211276869A CN115337972B CN 115337972 B CN115337972 B CN 115337972B CN 202211276869 A CN202211276869 A CN 202211276869A CN 115337972 B CN115337972 B CN 115337972B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
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Abstract
The invention discloses a split type ultrafiltration centrifugal tube device, which comprises a filter cylinder, wherein the top end of the filter cylinder is provided with an end cover matched with the filter cylinder, a sealing component is arranged between the end cover and the filter cylinder, and an ultrafiltration membrane is arranged at the bottom in the filter cylinder; the bottom cover of cartridge filter is equipped with its matched with protective sheath, and the inside of protective sheath is provided with prevents the subassembly that flows backwards with milipore filter matched with, and the bottom of protective sheath is provided with its matched with collecting pipe. The invention not only can solve the problem of stock solution leakage caused by the loss of the sealing ring in the traditional sealing mode under the action of the sealing assembly, improve the sealing effect of the ultrafiltration centrifugal tube and avoid the waste of the stock solution, but also can prevent the backflow of the filtered liquid under the action of the backflow-preventing assembly, effectively ensure the filtering effect and efficiency of the stock solution and better meet the use requirements of people.
Description
Technical Field
The invention relates to the technical field of centrifugal tubes, in particular to a split type ultrafiltration centrifugal tube device.
Background
The ultrafiltration centrifugal tube has a rapid ultrafiltration function, can achieve a higher concentration coefficient, and is easy to recover concentrated solution from the combination of diluent and a complex sample. The ultrafiltration centrifugal tube is mainly used for concentrating biological samples containing antigens, antibodies, enzymes, nucleic acids (single-strain or double-strain DNA/RNA samples), microorganisms, eluate and purified samples; purifying macromolecular components in the tissue culture medium extract and the cell lysate, removing primers, linkages or molecular markers from the reaction mixture, and removing proteins prior to High Performance Liquid Chromatography (HPLC); desalting, buffer exchange or diafiltration, etc.
For example, chinese patent CN217368460U discloses an ultrafiltration centrifugal tube, which comprises an outer tube, a cap tube and an inner tube, wherein the cap tube is detachably connected with the outer tube and encloses with the outer tube to form an accommodating cavity; the inner tube joint is holding the intracavity, and wherein, the interior week of lid pipe sets up the first chimb of round, and the top periphery of inner tube sets up round second chimb, and second chimb joint is between the top terminal surface of first chimb and outer tube, and it can realize the stability of inner tube in centrifugal process, makes its difficult production rock, improves centrifugal effect.
However, when the ultrafiltration centrifugal tube performs accelerated centrifugal filtration on a stock solution through a centrifuge, due to the lack of a corresponding sealing component between the accommodating cavity and the cover tube, leakage is easy to occur at the tube opening, so that certain waste of the stock solution is easy to occur; in addition, this ultrafiltration centrifuging tube can't play the effect that prevents the liquid refluence after filtering in the centrifugation with higher speed filtration process to not only influence the filter effect of stoste easily, greatly reduced the filter effect of stoste moreover, can not satisfy the user demand in people well.
An effective solution to the problems in the related art has not been proposed yet.
Disclosure of Invention
Aiming at the problems in the related art, the invention provides a split type ultrafiltration centrifugal tube device to overcome the technical problems in the prior related art.
Therefore, the invention adopts the following specific technical scheme:
a split type ultrafiltration centrifugal tube device comprises a filter cylinder, wherein an end cover matched with the filter cylinder is arranged at the top end of the filter cylinder, a sealing assembly is arranged between the end cover and the filter cylinder, and an ultrafiltration membrane is arranged at the bottom in the filter cylinder; the bottom of the filter cartridge is sleeved with a protective sleeve matched with the filter cartridge, a backflow prevention component matched with the ultrafiltration membrane is arranged inside the protective sleeve, and a collecting pipe matched with the protective sleeve is arranged at the bottom of the protective sleeve.
Further, in order to facilitate the centrifugal filtration of the stock solution, the filter cartridge comprises a vertical part, and a conical filter part is arranged at the bottom end of the vertical part; all pass through threaded connection between the bottom of vertical portion and the top of protective sheath, between the bottom of protective sheath and the top of collecting pipe, the outside of toper filter house is run through and is seted up a plurality of and milipore filter matched with filtration pore.
Further, in order to facilitate the installation and the placement of the sealing assembly, the mounting groove matched with the filter cartridge and the sealing assembly is formed in the outer side of the bottom of the end cover, first external threads are formed in the inner wall of the mounting groove, and the outer wall of the mounting groove is in contact with the outer wall of the top end of the filter cartridge.
Further, in order to solve the emergence of the former liquid seepage phenomenon that brings because of the sealing washer consume in traditional sealing method effectively, improve the sealed effect of ultrafiltration centrifuging tube, avoid the emergence of the extravagant condition of former liquid, seal assembly is including installing the first sealing member in cartridge filter top, and the inboard of first sealing member is provided with matched with second sealing member with it, and the inboard of second sealing member and the interior wall connection of mounting groove. The first sealing element comprises a first connecting part fixedly connected with the side wall of the top in the filter cartridge, a first sealing part is arranged on the inner side of the bottom end of the first connecting part, and a first inclined part is arranged on the inner side of the first connecting part in a downward inclined mode. The second sealing element comprises a second connecting part connected with the inner wall of the mounting groove, a second sealing part is arranged on one side of the top end of the second connecting part, one end, far away from the second connecting part, of the second sealing part is in contact with the inner side of the top end of the first connecting part, and a second inclined part is obliquely arranged on one side of the second connecting part; first internal thread matched with first external screw thread is seted up to the inboard of second connecting portion, and the inboard bottom of second connecting portion is provided with the sealing washer, and the inboard bottom of mounting groove seted up with sealing washer matched with seal groove. First sealing portion is including installing in the inboard slope section in first connecting portion bottom, and the one end that first connecting portion were kept away from to the slope section is provided with the horizontal segment, and the horizontal segment is kept away from the one side of slope section and the bottom outside contact of second connecting portion. A first leakage-proof cavity is formed between the first inclined part and the first sealing part, and the second inclined part is obliquely arranged in the first leakage-proof cavity from the second connecting part to the first connecting part; a second leakage-proof cavity is formed between the second inclined part and the second sealing part, and the first inclined part is obliquely arranged in the second leakage-proof cavity from the first connecting part to the second connecting part; the cross section of second sealing portion is the right trapezoid structure, and the top of second sealing portion contacts with the interior top of mounting groove, and the top surface of second sealing portion is parallel with the interior top surface of mounting groove, and the bottom surface of second sealing portion is parallel with the top surface of first slope.
Furthermore, in order to facilitate the connection and the disassembly between the protective sleeve and the filter cartridge as well as between the protective sleeve and the collecting pipe, the outer side of the top end of the protective sleeve and the outer side of the top end of the collecting pipe are both provided with an extending part in an upward extending manner, and the inner wall of each extending part is provided with a second external thread; the bottom outer side of the vertical portion and the bottom outer side of the protective sleeve are both upwards provided with a sunken portion matched with the extending portion, and the inner wall of the sunken portion is provided with a second inner thread matched with the second outer thread.
Furthermore, in order to effectively prevent the backflow of the filtered liquid and ensure the filtering effect and efficiency of the stock solution, the backflow preventing component comprises a fixing ring which is arranged on the inner side of the top of the protective sleeve and is positioned below the extension part, a liquid collecting hopper which is matched with the conical filtering part is arranged on the inner side of the fixing ring, and the inner wall of the liquid collecting hopper is contacted with the outer wall of the conical filtering part; the inner wall of the liquid collecting bucket is uniformly provided with a plurality of liquid collecting tanks matched with the filtering holes, the size of each liquid collecting tank is the same as that of each filtering hole, and the bottom end of the liquid collecting bucket is uniformly provided with liquid collecting ports communicated with the bottom end of each liquid collecting tank.
The invention has the beneficial effects that:
1) Through being provided with seal assembly and anti-backflow assembly to not only can solve the former liquid seepage phenomenon's that brings because of the sealing washer consume emergence in the traditional sealing mode under seal assembly's effect, improve ultrafiltration centrifuging tube's sealed effect, avoid the emergence of the extravagant condition of former liquid, but also can play the emergence that prevents to filter back liquid refluence phenomenon under anti-backflow assembly's effect, guarantee the filter effect and the efficiency of former liquid effectively, satisfy in people's user demand better.
2) Through being provided with seal assembly, thereby not only can play the double seal effect under the effect of first seal and second seal, and can also be at first leakage-proof chamber, the second rake, the second leakage-proof chamber and the effect of first rake are down prevented, make even take place in the stoste seepage also can be with the stoste backward flow cartridge filter of seepage between first seal and the second connecting portion, thereby can solve the emergence of the stoste seepage phenomenon that brings because of the sealing washer consume among the traditional sealing mode effectively, and then can improve the sealed effect of ultrafiltration of centrifuging tube effectively, avoid the emergence of the extravagant condition of stoste, satisfy in people's user demand better.
3) Through being provided with the anti-backflow subassembly, make the stock solution after the milipore filter filters can flow in the collecting tank inside, and flow in the collecting pipe from a collection liquid mouth under the effect of gravity inside, realize the collection to the liquid after filtering, simultaneously because the liquid after filtering only flows in the collecting pipe by the collecting tank that the slope set up and narrow and small collection liquid mouth, thereby can play the emergence that prevents to filter back liquid refluence phenomenon effectively, the filter effect and the efficiency of stock solution have been guaranteed effectively, can satisfy in people's user demand better.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a split-type ultrafiltration centrifugal tube device according to an embodiment of the invention;
FIG. 2 is a perspective assembly view of a split-type eppendorf tube device according to an embodiment of the present invention;
FIG. 3 is a cross-sectional view of FIG. 2;
FIG. 4 is a schematic structural diagram of a filter cartridge in a split ultrafiltration centrifuge tube apparatus according to an embodiment of the present invention;
FIG. 5 is an enlarged partial schematic view of FIG. 4 at A;
FIG. 6 is a schematic structural diagram of an end cap of a split ultrafiltration centrifuge tube apparatus according to an embodiment of the present invention;
FIG. 7 is a schematic view of a seal assembly of a split-type eppendorf tube device according to an embodiment of the present invention;
FIG. 8 is a schematic structural diagram of an anti-backflow assembly in a split-type ultrafiltration centrifuge tube apparatus according to an embodiment of the present invention;
fig. 9 is a partial structural view at B in fig. 8.
In the figure:
1. a filter cartridge; 101. a vertical portion; 102. a conical filter section; 103. a filtration pore; 2. an end cap; 201. mounting grooves; 202. a first external thread; 203. a sealing groove; 3. a seal assembly; 301. a first seal member; 302. a second seal member; 303. a first connection portion; 304. a first seal portion; 3041. an inclined section; 3042. a horizontal segment; 305. a first inclined portion; 306. a second connecting portion; 307. a second seal portion; 308. a second inclined portion; 309. a first internal thread; 310. a seal ring; 311. a first leakage-proof cavity; 312. a second leakage-proof cavity; 4. ultrafiltration membranes; 5. a protective sleeve; 6. a backflow prevention assembly; 601. a fixing ring; 602. a liquid collecting hopper; 603. a liquid collecting tank; 604. a liquid collection port; 7. a collection pipe; 8. an extension portion; 9. a second external thread; 10. a recessed portion; 11. a second internal thread.
Detailed Description
For further explanation of the various embodiments, the drawings which form a part of the disclosure and which are incorporated in and constitute a part of this specification, illustrate embodiments and, together with the description, serve to explain the principles of operation of the embodiments, and to enable others of ordinary skill in the art to understand the various embodiments and advantages of the invention, and, by reference to these figures, reference is made to the accompanying drawings, which are not to scale and wherein like reference numerals generally refer to like elements.
According to an embodiment of the invention, a split-type eppendorf tube device is provided.
Referring to the drawings and the detailed description, as shown in fig. 1-3, a split ultrafiltration centrifugal tube apparatus according to an embodiment of the present invention includes a filter cartridge 1, an end cap 2 is disposed at a top end of the filter cartridge 1, a sealing assembly 3 is disposed between the end cap 2 and the filter cartridge 1, and an ultrafiltration membrane 4 is disposed at an inner bottom of the filter cartridge 1; the bottom cover of cartridge filter 1 is equipped with matched with protective sheath 5 with it, and the inside of protective sheath 5 is provided with prevents the subassembly 6 that flows backwards with 4 matched with of milipore filter, and the bottom of protective sheath 5 is provided with matched with collecting pipe 7 with it, and during the concrete application, cartridge filter 1, end cover 2, protective sheath 5, prevent that the raw and other materials of flowing backwards subassembly 6 and collecting pipe 7 in this embodiment all adopt medical grade polypropylene aggregate to make, have the incompatibility, have guaranteed the toughness of product body again simultaneously.
By means of the above-mentioned technical scheme, through being provided with seal assembly 3 and anti-backflow subassembly 6, thereby not only can solve the emergence of the former liquid seepage phenomenon that brings because of the sealing washer consume in traditional sealing mode under seal assembly 3's effect, improve the sealed effect of ultrafiltration centrifuging tube, avoid the emergence of the extravagant condition of former liquid, and can also play the emergence that prevents the liquid refluence phenomenon after filtering under the effect of anti-backflow subassembly 6, guarantee the filter effect and the efficiency of former liquid effectively, satisfy in people's user demand better.
In one embodiment, as shown in fig. 1 and 4, the filter cartridge 1 comprises a vertical part 101, and the bottom end of the vertical part 101 is provided with a conical filter part 102, so as to facilitate centrifugal filtration of the stock solution; between the bottom of vertical portion 101 and the top of protective sheath 5, all pass through threaded connection between the bottom of protective sheath 5 and the top of collecting pipe 7, thereby be convenient for realize installation and the dismantlement between protective sheath 5 and cartridge filter 1 and the collecting pipe 7, during the specific application, in order to improve the sealed effect between protective sheath 5 and the collecting pipe 7, the former liquid takes place the seepage from between the junction of protective sheath 5 and collecting pipe 7 in the avoidance of centrifugal filtration process, the sealed mode between cartridge filter 1 and the end cover 2 can be adopted in being connected between protective sheath 5 and the collecting pipe 7 and seal (adopt seal assembly 3's mode promptly to seal), the outside of toper filter portion 102 is run through and is seted up a plurality of and ultrafiltration membrane 4 matched with filtration pore 103, during the specific application, filtration pore 103 and ultrafiltration membrane 4 all adopt fan-shaped structure.
In an embodiment, as shown in fig. 2, 5 and 6, an installation groove 201 is formed on an outer side of a bottom of the end cap 2, the installation groove is matched with the filter cartridge 1 and the sealing assembly 3, a first external thread 202 is formed on an inner wall of the installation groove 201, and an outer wall of the installation groove 201 is in contact with an outer wall of a top end of the filter cartridge 1, so that the installation and placement of the sealing assembly 3 are facilitated, and in a specific application, a thickness of the installation groove 201 may be slightly smaller than a sum of thicknesses of the filter cartridge 1 and the sealing assembly 3, so that the sealing assembly 3 can achieve a better sealing effect.
In one embodiment, as shown in fig. 3 and fig. 6 to 7, the sealing assembly 3 includes a first sealing element 301 fixedly installed at the top portion in the filter cartridge 1, a second sealing element 302 matched with the first sealing element 301 is disposed on the inner side of the first sealing element 301, and the inner side of the second sealing element 302 is detachably connected with the inner wall of the installation groove 201 through a thread, in particular, when the sealing assembly is applied, the second sealing element 302 in this embodiment may also be fixedly connected with the end cover 2 (the end cover 2 and the second sealing element 302 are both an integral component and are detachably connected without a thread), and both the first sealing element 301 and the second sealing element 302 are made of rubber. The first sealing member 301 includes a first connecting portion 303 fixedly connected to the inner top side wall of the filter cartridge 1, a first sealing portion 304 is provided at the inner side of the bottom end of the first connecting portion 303, and a first inclined portion 305 is provided at the inner side of the first connecting portion 303 in a downward inclined manner. The second sealing member 302 comprises a second connecting part 306 connected with the inner wall of the mounting groove 201, a second sealing part 307 is arranged on one side of the top end of the second connecting part 306, one end of the second sealing part 307 far away from the second connecting part 306 is contacted with the inner side of the top end of the first connecting part 303, and a second inclined part 308 is arranged on one side of the second connecting part 306 in a downward inclined mode; the inner side of the second connecting portion 306 is provided with a first inner thread 309 matched with the first outer thread 202, the bottom of the inner side of the second connecting portion 306 is provided with a sealing ring 310, and the bottom of the inner side of the mounting groove 201 is provided with a sealing groove 203 matched with the sealing ring 310. The first sealing portion 304 includes an inclined section 3041 installed at the inner side of the bottom of the first connecting portion 303, one end of the inclined section 3041 away from the first connecting portion 303 is provided with a horizontal section 3042, and one side of the horizontal section 3042 away from the inclined section 3041 contacts with the outer side of the bottom end of the second connecting portion 306. A first leakage-proof cavity 311 is formed between the first inclined portion 305 and the first sealing portion 304, and a second inclined portion 308 is provided in the first leakage-proof cavity 311 to be inclined downward from the second connecting portion 306 toward the first connecting portion 303; a second leakage-proof cavity 312 is formed between the second inclined portion 308 and the second sealing portion 307, and the first inclined portion 305 is arranged in the second leakage-proof cavity 312 in a manner of inclining downwards from the first connecting portion 303 toward the second connecting portion 306; the cross section of the second sealing portion 307 is a right trapezoid structure, the top end of the second sealing portion 307 contacts with the inner top of the mounting groove 201, the top surface of the second sealing portion 307 is parallel to the inner top surface of the mounting groove 201, and the bottom surface of the second sealing portion 307 is parallel to the top surface of the first inclined portion 305. Through being provided with seal assembly 3, thereby not only can play the double seal effect under the effect of first sealing 304 and second sealing 307, and can also be at first leakage-proof chamber 311, second slope 308, under the effect of second leakage-proof chamber 312 and first slope 305, make even take place the stoste seepage between first sealing 304 and the second connecting portion 306 and also can be with in the backward flow cartridge filter 1 of stock solution of seepage, thereby can solve the emergence of the stock solution seepage phenomenon that brings because of the sealing washer consume among the traditional sealing mode effectively, and then can improve the sealed effect of ultrafiltration centrifuging tube effectively, avoid the emergence of the extravagant condition of stock solution, better satisfy in people's user demand.
In this embodiment, for the installation of the sealing assembly 3, the second connecting portion 306 is only fixed on the inner top side wall of the filter cartridge 1 in advance (which may be fixed by gluing or other methods), then the connection between the end cap 2 and the first sealing element 301 can be achieved by threads, and finally, the assembly of the sealing assembly 3 is completed only by inserting the first sealing element 301 into the second sealing element 302 and pressing the end cap 2 downward, so that the first inclined portion 305 is located inside the second leakage-proof cavity 312 and the second inclined portion 308 is located inside the first leakage-proof cavity 311, respectively;
in the application process, firstly, a double sealing effect can be achieved under the action of the first sealing portion 304 and the second sealing portion 307, after long-term use, due to a tiny gap between the first sealing portion 304 and the second connecting portion 306, the raw liquid is easy to enter the first leakage-proof cavity 311 from the gap in centrifugal filtration, and the raw liquid entering the first leakage-proof cavity 311 is in contact with the inclined section 3041 or the second inclined portion 308, and under the action of the gravity of the raw liquid, the raw liquid flows to the horizontal section 3042 along the top of the inclined section 3041 (or the bottom of the second inclined portion 308 flows to the inclined section 3041 and flows to the horizontal section 3042 from the top of the inclined section 3041, where it should be noted that the length of the horizontal section 3042 is one tenth of the length of the inclined section 3041, so that the backflow effect of the raw liquid is not affected while the horizontal section 3042 is in contact with the second connecting portion 306, and the backflow effect of the raw liquid is facilitated to backflow from the gap filter cartridge to the inside of the filter cartridge 1, thereby achieving the backflow of the raw liquid, and the sealing assembly can be effectively improved by the use of the two sets of the leakage-proof cavities and the inclined portions 307, thereby effectively matching sealing assembly 3.
In one embodiment, as shown in fig. 3-5 and 9, the top outer side of the protective sleeve 5 and the top outer side of the collecting pipe 7 are both extended upwards to form an extension portion 8, and the inner wall of the extension portion 8 is both provided with a second external thread 9; the bottom outside of vertical portion 101 and the bottom outside of protective sheath 5 all upwards seted up with extension 8 matched with depressed part 10, the inner wall of depressed part 10 seted up with second external screw thread 9 matched with second internal thread 11 to be convenient for realize being connected and dismantling between protective sheath 5 and cartridge filter 1 and the collecting pipe 7.
In one embodiment, as shown in fig. 3-4 and 8-9, the backflow prevention assembly 6 comprises a fixing ring 601 installed inside the top of the protection sleeve 5 and below the extension portion 8, the fixing ring 601 is provided with a liquid collecting hopper 602 at the inner side thereof, the liquid collecting hopper 602 is matched with the conical filter 102, and the inner wall of the liquid collecting hopper 602 contacts with the outer wall of the conical filter 102; a plurality of liquid collecting grooves 603 matched with the filter holes 103 are uniformly formed in the inner wall of the liquid collecting hopper 602, the size and the shape of the liquid collecting grooves 603 are completely the same as those of the filter holes 103, and liquid collecting ports 604 communicated with the bottom end of the liquid collecting grooves 603 are uniformly formed in the bottom end of the liquid collecting hopper 602. Through being provided with anti-backflow component 6, make inside the former liquid after ultrafiltration membrane 4 filters can flow into collecting tank 603, and flow into collecting pipe 7 inside from album liquid mouth 604 under the effect of gravity, realize the collection to the liquid after filtering, simultaneously because the liquid after filtering only flows into collecting pipe 7 by the collecting tank 603 that the slope set up and narrow and small album liquid mouth 604, thereby can play the emergence that prevents to filter the back liquid refluence phenomenon effectively, the filter effect and the efficiency of former liquid have been guaranteed effectively, can satisfy in people's user demand better.
In summary, by means of the above technical scheme of the present invention, the sealing assembly 3 and the backflow prevention assembly 6 are provided, so that the occurrence of a stock solution leakage phenomenon caused by the loss of the sealing ring in the conventional sealing manner can be solved under the action of the sealing assembly 3, the sealing effect of the ultrafiltration centrifugal tube can be improved, the occurrence of a stock solution waste situation can be avoided, the occurrence of a liquid backflow phenomenon after filtration can be prevented under the action of the backflow prevention assembly 6, the filtration effect and efficiency of the stock solution can be effectively ensured, and the use requirements of people can be better satisfied.
In addition, through being provided with seal assembly 3, thereby not only can play the double seal effect under the effect of first sealing 304 and second sealing 307, and can also be at first leakage-proof chamber 311, second slope 308, under the effect of second leakage-proof chamber 312 and first slope 305, make even take place the stoste seepage between first sealing 304 and the second connecting portion 306 and also can be with the stoste backward flow cartridge filter 1 of seepage, thereby can solve the emergence of the stoste seepage phenomenon that brings because of the sealing washer consume among the traditional sealing mode effectively, and then can improve the sealed effect of ultrafiltration centrifuging tube effectively, avoid the emergence of the extravagant condition of stoste, better satisfy in people's user demand.
In addition, through being provided with anti-backflow component 6, make the stock solution after ultrafiltration membrane 4 filters can flow into the catch basin 603 inside, and flow into collecting pipe 7 inside from a collection liquid mouth 604 under the effect of gravity, realize the collection to the liquid after filtering, simultaneously because the liquid after filtering only flows into collecting pipe 7 by the catch basin 603 that the slope set up and narrow and small collection liquid mouth 604 in, thereby can play the emergence that prevents to filter the back liquid refluence phenomenon effectively, the filter effect and the efficiency of stock solution have been guaranteed effectively, can satisfy in people's user demand better.
In the present invention, unless otherwise explicitly stated or limited, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be understood broadly, for example, as being fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and should not be taken as limiting the scope of the present invention, which is intended to cover any modifications, equivalents, improvements, etc. within the spirit and scope of the present invention.
Claims (4)
1. A split type ultrafiltration centrifugal tube device comprises a filter cylinder (1), and is characterized in that an end cover (2) matched with the filter cylinder (1) is arranged at the top end of the filter cylinder (1), a sealing component (3) is arranged between the end cover (2) and the filter cylinder (1), and an ultrafiltration membrane (4) is arranged at the inner bottom of the filter cylinder (1);
the bottom end of the filter cartridge (1) is sleeved with a protective sleeve (5) matched with the filter cartridge, a backflow preventing component (6) matched with the ultrafiltration membrane (4) is arranged inside the protective sleeve (5), and a collecting pipe (7) matched with the protective sleeve is arranged at the bottom end of the protective sleeve (5);
the bottom outer side of the end cover (2) is provided with a mounting groove (201) matched with the filter cylinder (1) and the sealing assembly (3), the inner wall of the mounting groove (201) is provided with a first external thread (202), the outer wall of the mounting groove (201) is contacted with the top outer wall of the filter cylinder (1), the sealing assembly (3) comprises a first sealing element (301) arranged at the inner top of the filter cylinder (1), the inner side of the first sealing element (301) is provided with a second sealing element (302) matched with the first sealing element, the inner side of the second sealing element (302) is connected with the inner wall of the mounting groove (201), the first sealing element (301) comprises a first connecting part (303) fixedly connected with the inner top side wall of the filter cylinder (1), the bottom inner side of the first connecting part (303) is provided with a first sealing part (304), the inner side of the first connecting part (303) is provided with a first inclined part (305), the second sealing element (302) comprises a second connecting part (306) connected with the inner wall of the mounting groove (201), the top side of the second connecting part (306) is provided with a second connecting part (307), and the top end of the second connecting part (307) is contacted with the second sealing part (307), one side of the second connecting part (306) is provided with a second inclined part (308) in an inclined way; a first internal thread (309) matched with the first external thread (202) is formed in the inner side of the second connecting portion (306), a sealing ring (310) is arranged at the bottom of the inner side of the second connecting portion (306), a sealing groove (203) matched with the sealing ring (310) is formed in the bottom of the inner side of the mounting groove (201), the first sealing portion (304) comprises an inclined section (3041) mounted on the inner side of the bottom of the first connecting portion (303), a horizontal section (3042) is arranged at one end, far away from the first connecting portion (303), of the inclined section (3041), one side, far away from the inclined section (3042), of the horizontal section (3042) is in contact with the outer side of the bottom end of the second connecting portion (306), a first leakage-proof cavity (311) is formed between the first inclined portion (305) and the first sealing portion (304), and the second inclined portion (308) is arranged in the first leakage-proof cavity (311) from the second connecting portion (306) in a direction of the first connecting portion (303) in a downward inclination direction; a second leakage-proof cavity (312) is formed between the second inclined part (308) and the second sealing part (307), and the first inclined part (305) is obliquely downwards arranged in the second leakage-proof cavity (312) from the first connecting part (303) to the direction of the second connecting part (306); the cross section of the second sealing part (307) is of a right-angled trapezoid structure, the top end of the second sealing part (307) is in contact with the inner top of the mounting groove (201), the top surface of the second sealing part (307) is parallel to the inner top surface of the mounting groove (201), and the bottom surface of the second sealing part (307) is parallel to the top surface of the first inclined part (305).
2. The split ultrafiltration centrifuge tube device according to claim 1, wherein the filter cartridge (1) comprises a vertical part (101), and a conical filter part (102) is arranged at the bottom end of the vertical part (101);
the bottom end of the vertical part (101) is connected with the top end of the protective sleeve (5) through threads, the bottom end of the protective sleeve (5) is connected with the top end of the collecting pipe (7) through threads, and a plurality of filtering holes (103) matched with the ultrafiltration membrane (4) are formed in the outer side of the conical filtering part (102) in a penetrating mode.
3. The split ultrafiltration centrifugal tube device according to claim 2, wherein an extension part (8) extends upwards from the top of the protective sleeve (5) and from the top of the collecting tube (7), and the inner wall of the extension part (8) is provided with a second external thread (9);
the bottom outside of vertical portion (101) reaches the bottom outside of protective sheath (5) all upwards seted up with extension (8) matched with depressed part (10), the inner wall of depressed part (10) seted up with second external screw thread (9) matched with second internal thread (11).
4. The split ultrafiltration centrifuge tube device according to claim 3, wherein the backflow prevention assembly (6) comprises a fixing ring (601) installed inside the top of the protection sleeve (5) and below the extension part (8), a liquid collecting hopper (602) matched with the conical filter part (102) is arranged inside the fixing ring (601), and the inner wall of the liquid collecting hopper (602) is in contact with the outer wall of the conical filter part (102);
the inner wall of the liquid collecting hopper (602) is uniformly provided with a plurality of liquid collecting grooves (603) matched with the filtering holes (103), the size of each liquid collecting groove (603) is the same as that of each filtering hole (103), and the bottom end of the liquid collecting hopper (602) is uniformly provided with a liquid collecting port (604) communicated with the bottom end of each liquid collecting groove (603).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211276869.XA CN115337972B (en) | 2022-10-19 | 2022-10-19 | Split type ultrafiltration centrifuging tube device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211276869.XA CN115337972B (en) | 2022-10-19 | 2022-10-19 | Split type ultrafiltration centrifuging tube device |
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| Publication Number | Publication Date |
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| CN115337972A CN115337972A (en) | 2022-11-15 |
| CN115337972B true CN115337972B (en) | 2023-01-03 |
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Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN205253154U (en) * | 2015-12-22 | 2016-05-25 | 杭州费尔过滤技术有限公司 | Ultra -filtration centrifuge tube |
| CN108896364B (en) * | 2018-06-19 | 2021-08-03 | 河北医科大学 | Centrifugal ultrafiltration device for pretreatment of feed, livestock manure and tissue sample |
| CN210261612U (en) * | 2019-04-25 | 2020-04-07 | 南京川博生物技术有限公司 | Ultrafiltration tube for RXR- α phosphorylated antibody |
| CN213669894U (en) * | 2020-10-13 | 2021-07-13 | 艾杰科（天津）生物科技有限公司 | Integrated ultrafiltration centrifugal tube |
| CN215559990U (en) * | 2021-09-01 | 2022-01-18 | 北京青藤谷禧干细胞科技研究院有限公司 | Ultrafiltration tube for protein separation and purification |
| CN113951882A (en) * | 2021-11-12 | 2022-01-21 | 吉林省养蜂科学研究所（吉林省蜂产品质量管理监督站、吉林省蜜蜂遗传资源基因保护中心） | Extraction method and device of worker bee hemolymph |
| CN216964168U (en) * | 2022-01-29 | 2022-07-15 | 杭州科百特过滤器材有限公司 | Ultrafiltration centrifuge tube assembly |
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