CN115322896A - Gene detection sampler with temperature control function - Google Patents
Gene detection sampler with temperature control function Download PDFInfo
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- CN115322896A CN115322896A CN202211245036.7A CN202211245036A CN115322896A CN 115322896 A CN115322896 A CN 115322896A CN 202211245036 A CN202211245036 A CN 202211245036A CN 115322896 A CN115322896 A CN 115322896A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/805—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis wherein the stirrers or the receptacles are moved in order to bring them into operative position; Means for fixing the receptacle
- B01F27/806—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis wherein the stirrers or the receptacles are moved in order to bring them into operative position; Means for fixing the receptacle with vertical displacement of the stirrer, e.g. in combination with means for pivoting the stirrer about a vertical axis in order to co-operate with different receptacles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/10—Maintenance of mixers
- B01F35/145—Washing or cleaning mixers not provided for in other groups in this subclass; Inhibiting build-up of material on machine parts using other means
- B01F35/146—Working under sterile conditions; Sterilizing the mixer or parts thereof
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/02—Internal fittings
- B65D25/10—Devices to locate articles in containers
- B65D25/101—Springs, elastic lips, or other resilient elements to locate the articles by pressure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
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Abstract
The invention discloses a gene detection sampler with a temperature control function, and relates to the technical field of medical inspection; the centrifugal type constant temperature box comprises a constant temperature box and a centrifugal tube, wherein an upper cover is rotatably arranged on the upper surface of the constant temperature box, a handle is fixedly arranged on one side of the upper cover, and a transparent window is fixedly arranged on one surface of the upper cover, which is far away from the constant temperature box; through the vertical decline of drive lift seat, the lift seat passes through the puddler and makes the vertical decline of fixed plate and stirring fan blade, and simultaneously, the first bevel gear of second bevel gear drive rotates, first bevel gear makes the puddler rotate through the dwang, the puddler makes stirring fan blade rotate through the fixed plate, after stirring fan blade descends to the inside of centrifuging tube, stirring fan blade rotates and stirs liquid sample and detection medicament in the centrifuging tube, thereby convenient realization the automatic stirring of liquid sample and detection medicament, and then the effectual convenience that improves stirring liquid sample and detection medicament, and simultaneously, the effectual stirring effect that has improved liquid sample and detection medicament.
Description
Technical Field
The invention relates to the technical field of medical examination, in particular to a gene detection sampler with a temperature control function.
Background
The gene is a genetic basic unit, carries DNA or RNA sequence of genetic information, transmits the genetic information to the next generation through replication, and guides the synthesis of protein to express the genetic information carried by the gene, thereby controlling the character expression of organism individuals. The gene detection is a technique for detecting DNA by blood, other body fluids or cells, and is a method for taking peripheral venous blood or other tissue cells of a detected person, amplifying the gene information, detecting the DNA molecular information in the cells of the detected person by a specific device, and analyzing whether the gene type, the gene defect and the expression function of the gene contained in the cells are normal or not, so that people can know the gene information of themselves, and can determine the cause of disease or predict the risk of the body to suffer from a certain disease. The gene detection sampler in the prior art has the following problems:
when carrying out gene detection to the liquid sample after gathering, need add the medicament that gene detection used to liquid sample in, and stir it, however prior art mostly stirs liquid sample and medicament in the centrifuge tube through artifical handheld tool, because the speed of manual stirring is slower, and can't stir liquid sample and detection medicament in the centrifuge tube evenly, thereby lead to the stirring of liquid sample and detection medicament comparatively inconvenient and the effect of stirring is relatively poor, and because artificial limitation, probably can leak the disinfection and the washing step of stirring tool, produce the sample easily and pollute and lead to the sample to become invalid, influence subsequent gene detection, to above-mentioned problem, the inventor provides a gene detection sample thief with temperature control function and is used for solving above-mentioned problem.
Disclosure of Invention
The stirring device aims to solve the problems that a liquid sample and a detection medicament are not convenient to stir and the stirring effect is poor; the invention aims to provide a gene detection sampler with a temperature control function.
In order to solve the technical problem, the invention adopts the following technical scheme: the utility model provides a gene detection sample thief with temperature control function, includes thermostated container and centrifuging tube, the upper surface of thermostated container rotates installs the upper cover, one side fixed mounting of upper cover has the handle, the one side fixed mounting that the thermostated container was kept away from to the upper cover has the transparent window, the one side fixed mounting that the thermostated container kept away from the upper cover has evenly distributed's base, the inner wall fixed mounting of thermostated container has heating device, heating device's last fixed surface installs places the board, place the board and keep away from the one side of heating device and set up evenly distributed's the hole of placing, the one end of centrifuging tube and the inner wall movable contact of placing the hole, place the board and keep away from heating device's one side fixed mounting and have clean pipe, it is equipped with fixed establishment to place between hole and the centrifuging tube, be equipped with moving mechanism in the upper cover, moving mechanism's surface is equipped with rabbling mechanism.
Preferably, fixed establishment is including the arc limiting plate, the inner wall fixed mounting of arc limiting plate has the slipmat, the inner wall of slipmat and the outer wall movable contact of centrifuging tube, place the inner wall of hole and seted up two through-holes, the inner wall fixed mounting of through-hole has the telescopic link, the piston end of telescopic link and the outer wall fixed connection of arc limiting plate, the outer wall movable sleeve of telescopic link is equipped with expanding spring, expanding spring's one end and the inner wall fixed connection of through-hole, expanding spring's the other end and the outer wall fixed connection of arc limiting plate.
Preferably, moving mechanism is including the movable plate, the upper surface of movable plate and the inner wall movable contact of upper cover, two first guide ways, two have been seted up to the inner wall of upper cover the equal sliding connection of inner wall of first guide way has first guide block, two the lower surface of first guide block and the last fixed surface of movable plate are connected, one side of upper cover is rotated and is installed two first lead screws, first lead screw runs through first guide way and rotates with first guide block screw and be connected, two the equal fixed mounting in one end of first lead screw has synchronizing wheel, two the transmission is connected with the hold-in range between the synchronizing wheel, one side of upper cover is fixed and is equipped with first motor, the drive output of first motor and the one end fixed connection of a first lead screw, the outer wall fixedly connected with first fixed block of first motor, one side of first fixed block and one side fixed connection of upper cover, the movable plate is kept away from the one side of first guide block and has seted up the second guide way, the inner wall sliding connection of second guide way has second guide block, one side of second motor fixed connection has second guide block and second guide block, second guide block and second guide block fixed connection are close to the outer wall and second guide block, second guide block and second guide screw fixed connection.
Preferably, the rabbling mechanism is including the montant, the one end of montant and the lower fixed surface of second guide block are connected, the montant is kept away from the one end of second guide block and has been seted up the cavity, two spouts have been seted up to the inner wall of cavity the equal sliding connection of inner wall of spout has the slider, two the outer wall fixed mounting of slider has the lifting sleeve, two the inner wall fixed mounting of slider has the lifting seat, the wearing groove has been seted up to the one end of lifting seat, be equipped with the dwang in the cavity, the dwang runs through the lifting seat and rotates with the lifting seat to be connected, the one end fixed mounting that the lifting seat was kept away from to the dwang has the puddler, the one end fixed mounting that the puddler was kept away from has the fixed plate, the fixed surface of fixed plate installs evenly distributed's stirring vane, the one end fixed mounting that the puddler was kept away from to the dwang has first bevel gear, the one end of lifting seat is equipped with the transfer line, the outer wall fixed mounting of transfer line has the second bevel gear, the one end fixed mounting of dwang has drive gear, the inner wall of cavity is equipped with pinion rack, the pinion rack runs through the wearing groove, pinion rack and drive gear meshes the connection, the outer wall of montant is equipped with the threaded rod, the one end of montant runs through the lifting sleeve and the output of the motor is connected with the lifting sleeve, the motor is close to the motor fixed connection of motor.
Preferably, the one end fixed mounting of seat goes up and down has first backup pad, the transfer line is kept away from one end of drive gear and one side of first backup pad and is rotated the connection, the inner wall fixed mounting of cavity has the bracing piece, the one end and the pinion rack fixed connection of bracing piece, the montant is kept away from the one end fixed mounting of second guide block and is had the second backup pad, the threaded rod is kept away from the one end of motor and the last fixed surface of second backup pad and is rotated the connection, the outer wall fixedly connected with third fixed block of motor, the lower fixed surface of third fixed block and second guide block is connected.
Compared with the prior art, the invention has the beneficial effects that:
1. the centrifuge tube is inserted into the placing hole, the arc-shaped limiting plates and the anti-slip pads are arranged in the placing hole, and the centrifuge tube is limited and fixed by the two arc-shaped limiting plates and the two anti-slip pads, so that the limitation and the fixation of the centrifuge tube are conveniently realized, the stability of the centrifuge tube during subsequent stirring operation is effectively improved, and meanwhile, the phenomenon that a liquid sample in the centrifuge tube overflows due to the fact that the centrifuge tube topples during stirring operation is avoided;
2. the movable plate is driven to move transversely, the movable plate enables the vertical rod to move transversely through the second guide block, and the second guide block drives the vertical rod to move longitudinally through driving the second guide block to slide longitudinally, so that transverse and longitudinal movement adjustment of the stirring fan blades is conveniently realized, and further, liquid samples and detection medicaments in centrifugal tubes at different positions can be conveniently stirred subsequently;
3. through the vertical decline of drive lift seat, the lift seat passes through the puddler and makes the vertical decline of fixed plate and stirring vane leaf, and simultaneously, the first bevel gear of second bevel gear drive rotates, first bevel gear makes the puddler rotate through the dwang, the puddler makes stirring vane leaf rotate through the fixed plate, after stirring vane leaf descends to the inside of centrifuging tube, stirring vane leaf rotates and stirs liquid sample and detection medicament in the centrifuging tube, thereby convenient realization the automatic stirring of liquid sample and detection medicament, and then the effectual convenience that improves stirring liquid sample and detection medicament, and simultaneously, the effectual stirring effect that improves liquid sample and detection medicament.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic view showing the external structure of an incubator according to the present invention;
FIG. 2 is a schematic sectional view of the incubator and the upper cover according to the present invention;
FIG. 3 is a schematic view showing the separation of the centrifuge tube and the placing hole according to the present invention;
FIG. 4 is a sectional view of the placing board of the present invention;
FIG. 5 is an enlarged view of portion A of FIG. 4 according to the present invention;
FIG. 6 is a sectional view of the upper cover of the present invention;
FIG. 7 is a schematic connection diagram of a moving plate stirring mechanism according to the present invention;
FIG. 8 is an enlarged view of portion B of FIG. 7 according to the present invention;
FIG. 9 is a schematic view of the connection of the stirring mechanism of the present invention;
FIG. 10 is a sectional view of the vertical bar of the present invention;
FIG. 11 is an enlarged view of section C of FIG. 10 according to the present invention;
FIG. 12 is an enlarged view of the portion D of FIG. 11 according to the present invention.
In the figure: 1. a thermostat; 11. an upper cover; 12. a handle; 13. a transparent window; 14. a base; 15. a heating device; 16. placing the plate; 161. cleaning the tube; 17. placing holes; 18. centrifuging the tube; 2. a fixing mechanism; 21. an arc limiting plate; 22. a non-slip mat; 23. a through hole; 24. a telescopic rod; 25. a tension spring; 3. a moving mechanism; 31. moving the plate; 32. a first guide groove; 33. a first guide block; 34. a first lead screw; 35. a synchronizing wheel; 36. a synchronous belt; 37. a first motor; 38. a first fixed block; 39. a second guide groove; 4. a second guide block; 41. a second motor; 42. a second fixed block; 43. a second lead screw; 5. a stirring mechanism; 51. a vertical rod; 52. a cavity; 53. a chute; 54. a slider; 55. a lifting sleeve; 56. a lifting seat; 561. penetrating a groove; 57. rotating the rod; 58. a stirring rod; 59. a fixing plate; 6. stirring fan blades; 61. a first bevel gear; 62. a first support plate; 63. a transmission rod; 64. a second bevel gear; 65. a transmission gear; 66. a support bar; 67. a toothed plate; 68. a threaded rod; 69. a second support plate; 7. a motor; 71. and a third fixing block.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example (b): as shown in fig. 1-12, the invention provides a gene detection sampler with a temperature control function, comprising an incubator 1 and a centrifugal tube 18, wherein a sampled and collected liquid sample can be placed in the centrifugal tube 18, an upper cover 11 is rotatably installed on the upper surface of the incubator 1, a heating device 15 is fixedly installed on the inner wall of the incubator 1, the heating device 15 can heat the liquid sample in the centrifugal tube 18 and keep the temperature constant (in practical use, the heating device 15 is a common heating device in the existing structure, and is provided with a heating wire, the liquid sample in the centrifugal tube 18 is kept at a proper temperature by heating of the heating device 15, in this embodiment, the temperature is kept at 25-40 ℃), a placing plate 16 is fixedly installed on the upper surface of the heating device 15, and a surface of the placing plate 16, which is far away from the heating device 15, is provided with evenly distributed placing holes 17, one end of a centrifugal tube 18 is in movable contact with the inner wall of the placing hole 17, the centrifugal tube 18 can be placed in the placing hole 17, a fixing mechanism 2 is arranged between the placing hole 17 and the centrifugal tube 18, when a liquid sample and a detection medicament in the centrifugal tube 18 need to be stirred, the fixing mechanism 2 can conveniently realize the fixation of the centrifugal tube 18, the stability of the centrifugal tube 18 during stirring operation is improved, a moving mechanism 3 is arranged in the upper cover 11, a stirring mechanism 5 is arranged on the surface of the moving mechanism 3, the moving mechanism 3 can conveniently realize the horizontal and longitudinal horizontal movement of the stirring mechanism 5, so that the liquid samples and the detection medicaments in the centrifugal tubes 18 can be stirred conveniently, the stirring mechanism 5 can stir the liquid sample and the detection medicament in the centrifugal tube 18, and the convenience of stirring the liquid sample and the detection medicament is improved, meanwhile, the working strength of inspectors is reduced.
Through adopting above-mentioned technical scheme, place behind a plurality of centrifuging tubes 18 inside when the many liquid sample after the collection and detect the medicament, through setting up fixed establishment 2, fixed establishment 2 is convenient for realize centrifuging tube 18 fixed, make stirring mechanism 5 absorb by fixed establishment 2 when stirring operation in-process and rabbling mechanism 5 break away from each centrifuging tube 18 disturbance of centrifuging tube 18, with the stability that improves centrifuging tube 18, through setting up moving mechanism 3, moving mechanism 3 is convenient for realize the horizontal and vertical horizontal migration of rabbling mechanism 5, thereby be convenient for stir the liquid sample in a plurality of centrifuging tubes 18 and detect the medicament, through setting up rabbling mechanism 5, rabbling mechanism 5 stirs the liquid sample in centrifuging tube 18 and detects the medicament, improve the convenience of stirring liquid sample and detection medicament, and simultaneously, reduce inspection personnel's working strength.
One side fixed mounting of upper cover 11 has handle 12, through pulling handle 12, can be convenient for the inspection personnel to open upper cover 11, one side fixed mounting that upper cover 11 kept away from thermostated container 1 has transparent window 13, through transparent window 13, be convenient for the inspection personnel to observe the collection condition of liquid sample, one side fixed mounting that thermostated container 1 kept away from upper cover 11 has evenly distributed's base 14, base 14 can improve thermostated container 1's stability, place one side fixed mounting that board 16 kept away from heating device 15 and have cleaning tube 161, the antiseptic solution can be deposited to cleaning tube 161's inside, and in the in-service use, the antiseptic solution in cleaning tube 161 can be changed, in an embodiment, antiseptic solution in cleaning tube 161 changes when rabbling mechanism 5 breaks away from cleaning tube 161 at every time (cleaning tube 161 bottom is provided with liquid pump and fluid-discharge tube, liquid pump and fluid-discharge tube and cleaning tube 161 all are provided with the solenoid valve, thereby control the opening of fluid-discharge tube through the solenoid valve, and inject liquid to cleaning tube 161 inside through liquid pump and solenoid valve, so as to reach the mesh of changing the antiseptic solution inside cleaning tube 161 when rabbling mechanism 5 gets into in cleaning tube, thereby when rabbling mechanism 5 gets into in cleaning tube, the cleaning tube's mechanism's 5 gets into, the inside is the cleaning tube 161 is the new gene detection of the antiseptic solution 161, thereby the detection mechanism 18 to avoid the contamination of the liquid sample in the detection mechanism, the detection mechanism of the inner of liquid sample 161.
Through adopting above-mentioned technical scheme, through setting up arc limiting plate 21, telescopic link 24 and expanding spring 25, when two telescopic links 24 and two expanding spring 25 extended, two telescopic links 24 and two expanding spring 25 made two adjacent arc limiting plates 21 remove in opposite directions, and two adjacent arc limiting plates 21 are spacing to placing centrifuging tube 18 in the hole 17, improve centrifuging tube 18's stability.
The inner wall fixed mounting of arc limiting plate 21 has slipmat 22, and the inner wall of slipmat 22 and the outer wall movable contact of centrifuging tube 18, arc limiting plate 21 can carry out spacing fixed through slipmat 22 to centrifuging tube 18, and simultaneously, slipmat 22 can improve the stability of the centrifuging tube 18 after spacing fixed.
Through adopting above-mentioned technical scheme, through setting up slipmat 22, arc limiting plate 21 carries out spacing fixed through slipmat 22 to centrifuging tube 18, and simultaneously, slipmat 22 improves the stability of centrifuging tube 18 after spacing fixed.
The moving mechanism 3 comprises a moving plate 31, the upper surface of the moving plate 31 is in movable contact with the inner wall of the upper cover 11, two first guide grooves 32 are formed in the inner wall of the upper cover 11, first guide blocks 33 are connected to the inner walls of the two first guide grooves 32 in a sliding mode, the first guide blocks 33 can slide transversely along the inner walls of the first guide grooves 32, the lower surfaces of the two first guide blocks 33 are fixedly connected with the upper surface of the moving plate 31, and the moving plate 31 can move transversely through the first guide blocks 33.
By adopting the above technical solution, when the first guide block 33 slides laterally along the inner wall of the first guide groove 32, the first guide block 33 moves the moving plate 31 laterally.
One side of the upper cover 11 is rotatably provided with two first lead screws 34, the first lead screws 34 penetrate through the first guide grooves 32 and are in threaded rotary connection with the first guide blocks 33, the first lead screws 34 can drive the first guide blocks 33 to transversely slide, one ends of the two first lead screws 34 are fixedly provided with synchronizing wheels 35, a synchronous belt 36 is in transmission connection between the two synchronizing wheels 35, one first lead screw 34 can enable the other first lead screw 34 to synchronously rotate in the same direction through the two synchronizing wheels 35 and the synchronous belt 36, one side of the upper cover 11 is fixedly provided with a first motor 37, the driving output end of the first motor 37 is fixedly connected with one end of one first lead screw 34, and the driving shaft of the first motor 37 can enable one first lead screw 34 to rotate by starting the first motor 37, the side, far away from the first guide block 33, of the moving plate 31 is provided with a second guide groove 39, the inner wall of the second guide groove 39 is connected with a second guide block 4 in a sliding manner, the second guide block 4 can slide longitudinally along the inner wall of the second guide groove 39, one side of the moving plate 31 is fixedly provided with a second motor 41, the driving output end of the second motor 41 is fixedly provided with a second lead screw 43, the second lead screw 43 can be rotated by starting the second motor 41 through the driving shaft of the second motor 41, one end, close to the second motor 41, of the second lead screw 43 is rotatably connected with one side of the moving plate 31, the second lead screw 43 penetrates through the second guide groove 39 and is in threaded rotary connection with the second guide block 4, and the second lead screw 43 can drive the second guide block 4 to slide longitudinally.
By adopting the above technical solution, by starting the first motor 37, the driving shaft of the first motor 37 rotates one first lead screw 34, one first lead screw 34 rotates the other first lead screw 34 synchronously and in the same direction through the two synchronizing wheels 35 and the timing belt 36, the two first lead screws 34 slide the two first guide blocks 33 transversely, by starting the second motor 41, the driving shaft of the second motor 41 rotates the second lead screw 43, and the second lead screw 43 drives the second guide block 4 to slide longitudinally along the inner wall of the second guide groove 39.
The outer wall of the first motor 37 is fixedly connected with a first fixing block 38, one side of the first fixing block 38 is fixedly connected with one side of the upper cover 11, the first fixing block 38 can support and fix the first motor 37, the outer wall of the second motor 41 is fixedly connected with a second fixing block 42, one side of the second fixing block 42 is fixedly connected with one side of the moving plate 31, and the second fixing block 42 can support and fix the second motor 41.
By adopting the above technical solution, by arranging the first fixing block 38 and the second fixing block 42, the first fixing block 38 supports and fixes the first motor 37, and the second fixing block 42 supports and fixes the second motor 41.
Rabbling mechanism 5 is including montant 51, the one end of montant 51 and the lower fixed surface connection of second guide block 4, second guide block 4 can make montant 51 longitudinal movement, montant 51 keeps away from the one end of second guide block 4 and has seted up cavity 52, two spout 53 have been seted up to the inner wall of cavity 52, the equal sliding connection of inner wall of two spout 53 has slider 54, slider 54 can slide along the vertical direction of inner wall of spout 53, the outer wall fixed mounting of two slider 54 has lifting cover 55, lifting cover 55 can drive the vertical direction of slider 54 and slide, the inner wall fixed mounting of two slider 54 has lift seat 56, slider 54 can make the vertical direction of lift seat 56 remove, wear groove 561 has been seted up to the one end of lift seat 56, be equipped with dwang 57 in the cavity 52, dwang 57 runs through lift seat 56 and rotates with lift seat 56 and is connected, the one end fixed mounting that the dwang 57 kept away from lift seat 56 has stirring rod 58, the one end fixed mounting that stirring rod 58 kept away from dwang 57 has fixed plate 59, the fixed surface mounting of fixed plate 59 has evenly distributed's, lift seat 56 can make fixed plate 59 and stirring fan blade 6 direction remove through dwang 57 and stirring blade 6 direction through dwang 58.
By adopting the above technical scheme, through driving the lifting sleeve 55 to move in the vertical direction, the lifting sleeve 55 drives the slider 54 to slide along the vertical direction of the inner wall of the chute 53, the slider 54 enables the lifting seat 56 to move in the vertical direction, the lifting seat 56 enables the fixing plate 59 and the stirring fan blades 6 to move in the vertical direction through the rotating rod 57 and the stirring rod 58, it should be noted that, after the fixing plate 59 and the stirring fan blades 6 stir the liquid sample in one centrifuge tube 18, the stirring rod 58 is enabled to move to the position right above the cleaning tube 161 and enables the stirring rod 58 to descend, the stirring rod 58 enables the fixing plate 59 and the stirring fan blades 6 to descend into the cleaning tube 161 and contact with the disinfectant in the cleaning tube 161, and at the same time, the stirring rod 58 is enabled to rotate, the stirring rod 58 enables the fixing plate 59 and the stirring fan blades 6 to rotate, thereby realizing the automatic disinfection of the stirring rod 58, the fixing plate 59 and the stirring fan blades 6, and facilitating the stirring of the liquid sample and the detection reagent in the next centrifuge tube 18.
One end of the rotating rod 57 far away from the stirring rod 58 is fixedly provided with a first bevel gear 61, the first bevel gear 61 can enable the rotating rod 57 to rotate, one end of the lifting seat 56 is provided with a transmission rod 63, the outer wall of the transmission rod 63 is fixedly provided with a second bevel gear 64, the transmission rod 63 can enable the second bevel gear 64 to rotate, the second bevel gear 64 is in meshed connection with the first bevel gear 61, the second bevel gear 64 can drive the first bevel gear 61 to rotate, one end of the transmission rod 63 is fixedly provided with a transmission gear 65, the transmission gear 65 can enable the transmission rod 63 to rotate, the inner wall of the cavity 52 is fixedly provided with a toothed plate 67, when the lifting seat 56 moves in the vertical direction, the transmission rod 63 and the transmission gear 65 synchronously move up and down, the toothed plate 67 can drive the transmission gear 65 to rotate, the toothed plate 67 penetrates through a through groove 561, the toothed plate 67 is in meshed connection with the transmission gear 65, the outer wall of the vertical rod 51 is provided with a threaded rod 68, the threaded rod 68 penetrates through the lifting sleeve 55 and is in threaded connection with the lifting sleeve 55, the threaded rod 68 can drive the lifting sleeve 55 to move in the vertical direction, one side of the second guide block 4 close to the vertical rod 51 is fixedly provided with a motor 7, the drive output end of the motor 7 is fixedly connected with one end of the threaded rod 68 of the motor 7 fixedly connected with the threaded rod 68.
By adopting the above technical scheme, by turning on the motor 7, the drive shaft of the motor 7 rotates the threaded rod 68, the threaded rod 68 drives the lifting sleeve 55 to move in the vertical direction, the lifting sleeve 55 enables the lifting base 56 to move in the vertical direction through the sliding block 54, when the lifting base 56 moves in the vertical direction, the transmission rod 63 and the transmission gear 65 synchronously move up and down, the toothed plate 67 drives the transmission gear 65 to rotate, the transmission gear 65 enables the transmission rod 63 to rotate, the transmission rod 63 enables the second bevel gear 64 to rotate, the second bevel gear 64 drives the first bevel gear 61 to rotate, the first bevel gear 61 enables the rotation rod 57 to rotate, the rotation rod 57 enables the stirring rod 58 to rotate, the stirring rod 58 enables the stirring blades 6 to rotate through the fixing plate 59, so that the stirring blades 6 move in the vertical direction and synchronously rotate, and when the stirring blades 6 descend to the interior of the centrifuge tube 18, the stirring blades 6 stir the liquid sample and the detection reagent in the centrifuge tube 18.
One end of the lifting seat 56 is fixedly provided with a first supporting plate 62, one end of the transmission rod 63, which is far away from the transmission gear 65, is rotatably connected with one side of the first supporting plate 62, when the lifting seat 56 moves in the vertical direction, the lifting seat 56 enables the transmission rod 63 to synchronously move up and down through the first supporting plate 62, meanwhile, the first supporting plate 62 can support the transmission rod 63, the stability of the transmission rod 63 is improved, the inner wall of the cavity 52 is fixedly provided with a supporting rod 66, one end of the supporting rod 66 is fixedly connected with the toothed plate 67, the supporting rod 66 can fixedly support the toothed plate 67, one end of the vertical rod 51, which is far away from the second guide block 4, is fixedly provided with a second supporting plate 69, one end of the threaded rod 68, which is far away from the motor 7, is rotatably connected with the upper surface of the second supporting plate 69, the second supporting plate 69 can support the threaded rod 68, the stability of the threaded rod 68 is improved, the outer wall of the motor 7 is fixedly connected with a third fixing block 71, the third fixing block 71 is fixedly connected with the lower surface of the second guide block 4, and the third fixing block 71 can support and fix the motor 7.
Through adopting above-mentioned technical scheme, through setting up first backup pad 62, when lift seat 56 vertical direction removes, lift seat 56 makes the transfer line 63 reciprocate in step through first backup pad 62, and simultaneously, first backup pad 62 supports transfer line 63, improve the stability of transfer line 63, through setting up bracing piece 66, bracing piece 66 carries out the fixed stay to pinion rack 67, through setting up second backup pad 69, second backup pad 69 supports threaded rod 68, improve the stability of threaded rod 68, through setting up third fixed block 71, fixed motor 7 is supported to third fixed block 71.
The working principle is as follows: when a liquid sample and a detection reagent in a centrifuge tube 18 need to be stirred, a plurality of centrifuge tubes 18 containing the liquid sample and the detection reagent are vertically inserted into a plurality of placing holes 17 one by one, two arc-shaped limiting plates 21, two anti-slip pads 22, two telescopic rods 24 and two telescopic springs 25 are arranged in the plurality of placing holes 17, and two adjacent arc-shaped limiting plates 21 and two anti-slip pads 22 limit and fix one centrifuge tube 18, so that the limit and the fixation of the centrifuge tube 18 are conveniently realized, the stability of the centrifuge tube 18 in the subsequent stirring operation is effectively improved, and meanwhile, the phenomenon that the liquid sample in the centrifuge tube 18 overflows due to the toppling of the centrifuge tube 18 in the stirring operation is avoided;
subsequently, by starting the first motor 37, the driving shaft of the first motor 37 rotates one first lead screw 34, one first lead screw 34 rotates the other first lead screw 34 synchronously and simultaneously through two synchronizing wheels 35 and a synchronizing belt 36, the two first lead screws 34 make the two first guide blocks 33 slide laterally along the inner walls of the two first guide grooves 32, the two first guide blocks 33 make the moving plate 31 move laterally, and the moving plate 31 makes the vertical rod 51 move laterally through the second guide block 4;
by starting the second motor 41, the driving shaft of the second motor 41 rotates the second lead screw 43, the second lead screw 43 drives the second guide block 4 to longitudinally slide along the inner wall of the second guide groove 39, and the second guide block 4 longitudinally moves the vertical rod 51, so that the transverse and longitudinal movement adjustment of the stirring fan blades 6 is conveniently realized, and further, the subsequent stirring of liquid samples and detection medicaments in centrifuge tubes 18 at different positions is facilitated;
finally, after the vertical rod 51 moves transversely and longitudinally to a position right above one centrifugal tube 18, by turning on the motor 7, the drive shaft of the motor 7 rotates the threaded rod 68, the threaded rod 68 drives the lifting sleeve 55 to move vertically downwards, the lifting sleeve 55 drives the lifting seat 56 to move vertically downwards through the two sliders 54, when the lifting seat 56 moves vertically downwards, the transmission rod 63 and the transmission gear 65 synchronously move downwards, at this time, the toothed plate 67 drives the transmission gear 65 to rotate, the transmission gear 65 rotates the transmission rod 63, the transmission rod 63 rotates the second bevel gear 64, the second bevel gear 64 drives the first bevel gear 61 to rotate, the first bevel gear 61 rotates the rotating rod 57, the rotating rod 57 rotates the stirring rod 58, the stirring rod 58 rotates the stirring fan blades 6 through the fixing plate 59, after the stirring fan blades 6 descend into the centrifugal tube 18, the stirring fan blades 6 rotate and stir the liquid sample and the detection reagent in one centrifugal tube 18, so that automatic stirring of the liquid sample and the detection reagent is conveniently realized, and convenience of stirring the liquid sample and the detection reagent is effectively improved;
after the fixing plate 59 and the stirrer blade 6 stir the liquid sample and the detection reagent in one centrifuge tube 18, the stirrer rod 58 is moved to a position right above the cleaning tube 161, and the stirrer rod 58 is lowered, so that the fixing plate 59 and the stirrer blade 6 are lowered into the cleaning tube 161 by the stirrer rod 58 and are contacted with the disinfectant in the cleaning tube 161, and at the same time, the stirrer rod 58 is rotated, the fixing plate 59 and the stirrer blade 6 are rotated by the stirrer rod 58, and the stirring mechanism 5 is cleaned inside the cleaning tube 161, and in actual use, the disinfectant in the cleaning tube 161 is replaced each time the stirring mechanism 5 is separated from the cleaning tube 161, so that the automatic disinfection of the stirrer rod 58, the fixing plate 59 and the stirrer blade 6 is realized, the liquid sample and the detection reagent in the next centrifuge tube 18 are stirred, the pollution of the liquid sample in the centrifuge tube 18 is fully avoided, and the gene detection effect is ensured.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (10)
1. The utility model provides a gene detection sample thief with temperature control function, includes thermostated container (1) and centrifuging tube (18), its characterized in that, the upper surface of thermostated container (1) rotates installs upper cover (11), the inner wall fixed mounting of thermostated container (1) has heating device (15), the last fixed surface of heating device (15) installs places board (16), place the one side that board (16) kept away from heating device (15) and set up evenly distributed place hole (17), the one end of centrifuging tube (18) and the inner wall movable contact of placing hole (17), it is equipped with fixed establishment (2) to place between hole (17) and centrifuging tube (18), be equipped with moving mechanism (3) in upper cover (11), the surface of moving mechanism (3) is equipped with rabbling mechanism (5).
2. The gene detection sampler with temperature control function according to claim 1, wherein a handle (12) is fixedly installed on one side of the upper cover (11), a transparent window (13) is fixedly installed on one surface of the upper cover (11) far away from the incubator (1), uniformly distributed bases (14) are fixedly installed on one surface of the incubator (1) far away from the upper cover (11), and cleaning tubes (161) are fixedly installed on one surface of the placing plate (16) far away from the heating device (15).
3. The gene detection sampler with the temperature control function according to claim 1, wherein the fixing mechanism (2) comprises an arc-shaped limiting plate (21), two through holes (23) are formed in the inner wall of the placing hole (17), an expansion link (24) is fixedly mounted on the inner wall of each through hole (23), the piston end of each expansion link (24) is fixedly connected with the outer wall of the arc-shaped limiting plate (21), an expansion spring (25) is movably sleeved on the outer wall of each expansion link (24), one end of each expansion spring (25) is fixedly connected with the inner wall of each through hole (23), and the other end of each expansion spring (25) is fixedly connected with the outer wall of each arc-shaped limiting plate (21).
4. The gene detection sampler with the temperature control function as claimed in claim 3, wherein the inner wall of the arc-shaped limiting plate (21) is fixedly provided with a non-slip mat (22), and the inner wall of the non-slip mat (22) is in movable contact with the outer wall of the centrifuge tube (18).
5. The gene detection sampler with the temperature control function according to claim 1, wherein the moving mechanism (3) comprises a moving plate (31), the upper surface of the moving plate (31) is movably contacted with the inner wall of the upper cover (11), the inner wall of the upper cover (11) is provided with two first guide grooves (32), the inner walls of the two first guide grooves (32) are both slidably connected with first guide blocks (33), and the lower surfaces of the two first guide blocks (33) are fixedly connected with the upper surface of the moving plate (31).
6. The gene detection sampler with the temperature control function according to claim 5, wherein two first lead screws (34) are rotatably mounted on one side of the upper cover (11), the first lead screws (34) penetrate through the first guide grooves (32) and are rotatably connected with the first guide blocks (33) in a threaded manner, one end of each of the two first lead screws (34) is fixedly mounted with a synchronizing wheel (35), a synchronizing belt (36) is connected between the two synchronizing wheels (35) in a transmission manner, one side of the upper cover (11) is fixedly provided with a first motor (37), a driving output end of the first motor (37) is fixedly connected with one end of one first lead screw (34), a second guide groove (39) is formed in one side of the movable plate (31) far away from the first guide blocks (33), a second guide block (4) is slidably connected with the inner wall of the second guide groove (39), one side of the movable plate (31) is fixedly provided with a second motor (41), a driving output end of the second motor (41) is fixedly mounted with a second lead screw (43), one end of the second lead screw (43) close to the second guide groove (41) is rotatably connected with one end of the second lead screw (41), and the second guide block (39) penetrates through the movable plate (43).
7. The gene assaying sampler with temperature control function according to claim 6, wherein a first fixing block (38) is fixedly connected to an outer wall of the first motor (37), one side of the first fixing block (38) is fixedly connected to one side of the upper cover (11), a second fixing block (42) is fixedly connected to an outer wall of the second motor (41), and one side of the second fixing block (42) is fixedly connected to one side of the moving plate (31).
8. The gene detection sampler with the temperature control function according to claim 6, wherein the stirring mechanism (5) comprises a vertical rod (51), one end of the vertical rod (51) is fixedly connected with the lower surface of the second guide block (4), one end of the vertical rod (51) far away from the second guide block (4) is provided with a cavity (52), the inner wall of the cavity (52) is provided with two sliding grooves (53), the inner wall of the two sliding grooves (53) is slidably connected with a sliding block (54), the outer wall of the two sliding blocks (54) is fixedly provided with a lifting sleeve (55), the inner wall of the two sliding blocks (54) is fixedly provided with a lifting seat (56), one end of the lifting seat (56) is provided with a penetrating groove (561), a rotating rod (57) is arranged in the cavity (52), the rotating rod (57) penetrates through the lifting seat (56) and is rotatably connected with the lifting seat (56), one end of the rotating rod (57) far away from the lifting seat (56) is fixedly provided with a stirring rod (58), one end of the stirring rod (58) far away from the fixing plate (59) is fixedly provided with a fixing plate (59), and the stirring blades (6) are uniformly distributed on the surface of the fixing plate (6).
9. The gene detection sampler with the temperature control function according to claim 8, wherein a first bevel gear (61) is fixedly installed at one end of the rotating rod (57) far away from the stirring rod (58), a transmission rod (63) is arranged at one end of the lifting seat (56), a second bevel gear (64) is fixedly installed on the outer wall of the transmission rod (63), the second bevel gear (64) is meshed with the first bevel gear (61), a transmission gear (65) is fixedly installed at one end of the transmission rod (63), a toothed plate (67) is fixedly installed on the inner wall of the cavity (52), the toothed plate (67) penetrates through the through groove (561), the toothed plate (67) is meshed with the transmission gear (65), a threaded rod (68) is arranged on the outer wall of the vertical rod (51), the threaded rod (68) penetrates through the lifting sleeve (55) and is in threaded rotating connection with the lifting sleeve (55), a motor (7) is fixedly installed on one side of the second guide block (4) close to the vertical rod (51), and a driving output end of the motor (7) is fixedly connected with one end of the threaded rod (68).
10. The gene detection sampler with the temperature control function according to claim 9, wherein a first supporting plate (62) is fixedly mounted at one end of the lifting seat (56), one end of the transmission rod (63) far away from the transmission gear (65) is rotatably connected with one side of the first supporting plate (62), a supporting rod (66) is fixedly mounted on the inner wall of the cavity (52), one end of the supporting rod (66) is fixedly connected with the toothed plate (67), one end of the vertical rod (51) far away from the second guide block (4) is fixedly mounted with a second supporting plate (69), one end of the threaded rod (68) far away from the motor (7) is rotatably connected with the upper surface of the second supporting plate (69), a third fixing block (71) is fixedly connected with the outer wall of the motor (7), and the third fixing block (71) is fixedly connected with the lower surface of the second guide block (4).
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116159458A (en) * | 2023-02-14 | 2023-05-26 | 海安荣祥化纤有限公司 | Preparation facilities of high-efficient nylon conductive fiber |
| CN116250563A (en) * | 2022-11-23 | 2023-06-13 | 浙江星星冷链集成股份有限公司 | Yoghurt machine |
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| CN111304290A (en) * | 2020-03-16 | 2020-06-19 | 通用生物系统（安徽）有限公司 | Nucleic acid extraction method for gene sequencing |
| CN113337388A (en) * | 2021-06-22 | 2021-09-03 | 南京中科拜尔医学技术有限公司 | Full-automatic nucleic acid extraction instrument and operation method thereof |
| CN115144608A (en) * | 2022-07-02 | 2022-10-04 | 罗灵光 | Diabetes clinical sampling device and method for endocrine department |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111304290A (en) * | 2020-03-16 | 2020-06-19 | 通用生物系统（安徽）有限公司 | Nucleic acid extraction method for gene sequencing |
| CN113337388A (en) * | 2021-06-22 | 2021-09-03 | 南京中科拜尔医学技术有限公司 | Full-automatic nucleic acid extraction instrument and operation method thereof |
| CN115144608A (en) * | 2022-07-02 | 2022-10-04 | 罗灵光 | Diabetes clinical sampling device and method for endocrine department |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116250563A (en) * | 2022-11-23 | 2023-06-13 | 浙江星星冷链集成股份有限公司 | Yoghurt machine |
| CN116159458A (en) * | 2023-02-14 | 2023-05-26 | 海安荣祥化纤有限公司 | Preparation facilities of high-efficient nylon conductive fiber |
| CN116159458B (en) * | 2023-02-14 | 2023-11-14 | 海安荣祥化纤有限公司 | Preparation facilities of high-efficient nylon conductive fiber |
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