CN102854050A - Fully-automatic double-rail staining instrument for frozen sections - Google Patents

Fully-automatic double-rail staining instrument for frozen sections Download PDF

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Publication number
CN102854050A
CN102854050A CN2012103779418A CN201210377941A CN102854050A CN 102854050 A CN102854050 A CN 102854050A CN 2012103779418 A CN2012103779418 A CN 2012103779418A CN 201210377941 A CN201210377941 A CN 201210377941A CN 102854050 A CN102854050 A CN 102854050A
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staining
cylinder
provided
frozen sections
dyeing
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CN2012103779418A
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Chinese (zh)
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梁建中
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梁建中
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Priority to CN2012103779418A priority Critical patent/CN102854050A/en
Publication of CN102854050A publication Critical patent/CN102854050A/en

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Abstract

The invention discloses a fully-automatic double-rail staining instrument for frozen sections, comprising a box body, a control system, and a reagent cylinder arranged in the box body, wherein a first guide rail and a second guide rail are arranged in the long edge directions of the both sides of the box body respectively, and a first staining device and a second staining device are arranged on the first guide rail and the second guide rail respectively. The double-rail staining instrument for frozen sections provided by the invention can be used for staining two groups of the frozen sections respectively, and meet the requirement of rapid staining on the frozen sections; secondly, the quality difference caused by a manual operation is avoided by setting a standard operation time to normalize the staining process; reagents can be uniformly mixed via the up-and-down movement of a mechanical arm, thus reinforcing the staining effect; and replacement for the reagents is prompted by performing the alarm of the use critical points of the reagents, thus ensuring the quality of the stained sections. Therefore, the efficiency of staining the present clinical frozen sections in hospitals is increased, and the quality of staining the frozen sections is improved.

Description

全自动双轨道冷冻切片染色仪 Automatic dual-track frozen section Stainer

技术领域 FIELD

[0001] 本发明涉及一种医疗设备,具体涉及一种全自动冷冻切片染色仪。 [0001] The present invention relates to a medical device, particularly to an automatic analyzer stained cryosections.

背景技术 Background technique

[0002] 冷冻切片染色是一种向医生提供病理诊断切片的良好方法,然而,冷冻切片染色需要实现快速(一般整个过程只需要在5-10分钟内即可完成),即不断进行切片染色的过程。 [0002] Frozen sections were stained to provide a pathological diagnosis of the doctor sections a good method, however, requires fast staining cryosections (the whole process takes typically can be completed in 5-10 minutes), i.e., the ongoing stained process. 传统的冷冻切片染色均为人工操作过程,染色效果取决于操作人员的经验和习惯。 Frozen sections were stained traditional manual process, dyeing effect depends on the experience and habits of the operator. 而且,所使用的染色试剂涉及易挥发的有毒化学物质,操作人员长期接触身体会产生不良反应,损害身体健康,再者,也增加了人工成本和时间。 Moreover, staining reagents used involving volatile toxic chemicals, the operator of long-term contact with the body will produce adverse reactions, damage to health, moreover, also increased labor costs and time.

[0003] 虽然目前出现了用于常规切片染色的全自动的染色仪,但其染色方式是单轨染色,染色玻片数量固定,仪器体积大,同时单轨染色时因为上下的机械运动和计算机智能判另O,未能短时间内进行染色步骤的切换,容易造成染色效果的偏差。 [0003] Although there have been used in conventional automatic stainer stained, but the staining pattern monorail stained, fixed number of stained slides, a large volume of equipment, the same time as the mechanical motion of dyeing monorail down judgment and computer intelligence another O, failed to carry out a short time to switch staining procedure, likely to cause deviation dyeing. 因此,为保证冷冻切片染色质量和冷冻切片染色的工作效率,实现省力、省时、优质的效果,有必要研发一种可以符合冷冻切片染色原理的染色仪。 Therefore, to ensure the quality of frozen sections were stained frozen and efficiency, to achieve labor-saving, time-saving, high-quality results, it is necessary to develop a way consistent with the principles of frozen sections were stained instrument.

发明内容 SUMMARY

[0004] 为了克服现有技术的不足,本发明旨在于提供一种全自动双轨染色仪,通过机械化控制实现自动检测,一方面降低了人工成本,减少测试人员受污染的可能性,另一方面,提高了染色的质量,为医生判断疾病提出了良好的依据。 [0004] In order to overcome the deficiencies of the prior art, the present invention is intended to provide an automated stainer-track, detected by the mechanized automatic control, while reducing labor costs, reduce the possibility of contamination of the tester, on the other hand improve the quality of dyeing, presented a good basis for doctors to determine the disease.

[0005] 为了实现上述目的,本发明采用的技术方案如下: [0005] To achieve the above object, the present invention employs the following technical solutions:

[0006] 全自动双轨道冷冻切片染色仪,包括箱体,自动控制系统以及设置在所述箱体中的试剂缸,在所述箱体两侧的长边方向分别设有第一导轨和第二导轨,所述第一导轨和第二导轨上分别设有第一染色装置和第二染色装置。 [0006] Frozen sections automatic stainer double track, comprising a housing, an automatic control system, and a reagent disposed in said case cylinder, are provided in the longitudinal direction of the housing on both sides of the first and second guide rails two rails, respectively, with first and second means dyeing means dyeing said first and second rails.

[0007] 作为一种优选方案,所述第一染色装置包括底座,与所述底座电气连接的伺服电机,染色气缸,以及第一机械臂,所述气缸设置在所述底座的顶部,所述第一机械臂设置在所述气缸上,所述第一机械臂前端设有挂钩,所述底座设有与第一导轨相匹配的滚轮。 [0007] As a preferred embodiment, the first means includes a dye base, a servo motor connected to the electrical base, dyeing cylinder, and a first robot arm, a cylinder disposed on top of the base, the a first cylinder provided on the robot arm, the robot arm front end with a first hook, the base is provided with a first guide roller matches.

[0008] 作为一种优选方案,所述第二染色装置包括底座,与所述底座电气连接的伺服电机,染色气缸,以及第二机械臂,所述气缸设置在所述底座的顶部,所述第一机械臂设置在所述气缸上,所述第二机械臂前端设有挂钩,所述底座设有与第二导轨相匹配的滚轮。 [0008] As a preferred embodiment, the second dyeing apparatus includes a base, a servo motor connected to the electrical base, dyeing cylinder, and a second arm, the cylinder disposed on top of the base, the a first robot arm provided on said cylinder, with the front end of the second arm link, the base is provided with a second guide roller matches.

[0009] 作为一种优选方案,所述试剂缸顶部设有开合部件,所述开合部件由开盖、转动拉杆以及开合气缸组成,其中,所述转动拉杆的一端与开盖活动连接,其另一端连接于气缸。 [0009] As a preferred embodiment, the agent cylinder is provided with a top closure member, the closure member from the open end, and an opening closing cylinder rod is rotated, where the rotation of one end of the lid opening lever movably connected , the other end connected to the cylinder.

[0010] 作为一种优选方案,所述试剂缸设有5-25个。 [0010] As a preferred embodiment, the agent is provided with cylinder 5-25.

[0011] 相对于现有技术,本发明提供了一种双轨道冷冻切片染色仪,可分别进行双组冰冻切片染色,满足冷冻切片快速染色的要求;一方面通过设定标准操作时间规范染色过程,避免因为手工操作所带来的质量差异;另一方面还通过进行试剂使用失效临界点的报警,提示试剂更换而保证切片染色的质量。 [0011] with respect to the prior art, the present invention provides a two-track cryosections stainer, can be double-stained frozen sections were set to meet the requirements of rapid dyeing cryosections; by setting an aspect of the standard operating time specification dyeing process , avoid the quality difference caused by manual operation; quality is guaranteed also by another aspect of the stained using a reagent failure alarm critical point, suggesting reagent replacement. 通过机械臂的上下移动,使试剂能够混合均匀,加强染色效果。 Moved up and down by a robot arm, the reagent can be mixed to enhance the effect of dyeing. 从而提高现有医院临床冷冻切片染色的效率,改善冷冻切片染色的质量。 Thereby increasing the existing hospital clinical staining of frozen sections of efficiency, improve the quality of frozen sections were stained.

附图说明 BRIEF DESCRIPTION

[0012] 图I本发明的结构示意图; [0012] Figure I is a schematic structural diagram of the present invention;

[0013] 图2为图I中第一机械臂的结构示意图; [0013] FIG. 2 is a schematic structural view of a first manipulator in Figure I;

[0014] 图3为图I中试剂缸的截面示意图。 [0014] FIG. 3 is a schematic sectional view of a cylinder I reagent.

具体实施方式 Detailed ways

[0015] 下面将结合附图对本发明作进一步的描述。 [0015] The following with reference to the present invention will be further described.

[0016] 如图I所示,本发明包括箱体,自动控制系统以及设置在所述箱体中的试剂缸4,所述试剂缸4顺序排列在所述箱体中,在所述箱体两侧的长边方向分别设有第一导轨5和第二导轨6,所述第一导轨5和第二导轨6上分别活动连接有第一染色装置2和第二染色装置3。 [0016] As shown in FIG I, the present invention includes a case, an automatic control system, and a reagent disposed in the cylinder housing 4, the reagent in the cylinder housing 4 in order, in the housing on both sides of the longitudinal direction of the rail 5 are provided a first and second guide rails 6, are movably connected with a first and a second dyeing means dyeing device 2 3 5 on the first rail and the second rail 6.

[0017] 如图2所不,所述第一染色装置2由底座21,伺服电机22,染色气缸26以及第一机械臂23构成,其中,所述底座21电气连接于所述伺服电机22,所述染色气缸26设置于所述底座21的顶部,所述第一机械臂23固定连接在所述气缸26上的活塞杆上,所述第一机械臂23前端设有挂钩24,所述底座21底部设有与所述第一导轨5相匹配的滚轮25,相对于第二染色装置,其结构与第一染色装置相同,且位置相对设置。 [0017] FIG. 2 is not the first staining device 221, the servo motor 22, the cylinder 26 and the dyeing manipulator 23 consists of a first base, wherein the base 21 is electrically connected to the servo motor 22, the dyeing cylinder on the piston rod 26 is provided on the top 21 of the base, the first robot arm 23 is fixedly connected to the cylinder 26, the distal end of the arm 23 has a first hook 24, the base 21 is provided with a bottom rail 5 to match the first roller 25 relative to the second dyeing apparatus, its structure is the same as the first dyeing apparatus, and the position opposite.

[0018] 如图3所示,所述试剂缸4顶部设有开合部件,所述开合部件由开盖41、转动拉杆42以及开合气缸43组成,其中,所述转动拉杆42的一端与开盖41活动连接,其另一端连接于气缸43上的活塞杆。 [0018] As shown in FIG. 3, the agent cylinder 4 is provided with a top closure member, the closure member from the open end 41, rotation of the rod 42 and the opening and closing cylinder 43, where, one end of the rod 42 is rotated open end 41 connected to the activities which the other end is connected to the piston rod of the cylinder 43.

[0019] 进行检测时,首先将被测样品挂在第一机械臂的挂钩上,启动伺服电机,第一染色装置沿第一导轨运行至试剂缸上方,此时,设置在试剂缸顶部的开合部件开始运作,具体的说,通过开合气缸带动转动拉杆使开盖打开,然后,第一染色装置上的染色气缸启动,利用活塞杆的升降使第一机械臂降入试剂缸中对样品进行染色处理,此时,自动控制系统开始对染色时间进行计时,当染色时间到达设定值时,染色气缸动作升起后,第一染色装置沿第一导轨往下一个试剂缸运动,按照上述步骤重复,并按照所设置的试剂缸数进行重复,直至最后一个试剂缸结束后,自动控制系统将发出提示音,提示染色完毕。 [0019] When detected, the test sample is first hung on the hook of the first manipulator, servo motor starts, first staining run to the first rail means along the upper cylinder reagents, this time, the cylinder is provided at the top opening reagent operational engagement member, specifically, by rotation of the lever opening and closing drive cylinder so that opening the lid open, and then, dyeing the first cylinder to start dyeing apparatus, using a lifting rod of the first cylinder in the robot arm is lowered into the sample reagent dyeing process, this time, the automatic control system for timing the start of the dyeing time, dyeing when the time reaches the set value, the operation of the cylinder rises after dyeing, dyeing the first means along a first guide cylinder moving down a reagent, according to the above steps are repeated, and repeated by the number of cylinders provided in the reagent, a reagent until after the end of the last cylinder, the automatic control system will issue a beep, indicating completion of the dyeing. 而第二染色装置也是重复上述步骤,并且可以实现双轨并联,同时对不同样品进行染色,提高检测效率。 And the second means is dyed repeating the above steps, and may be implemented in parallel with the two-track, while the different samples were stained to improve the detection efficiency.

[0020] 对于本领域的技术人员来说,可根据以上描述的技术方案以及构思,做出其它各种相应的改变以及变形,而所有的这些改变以及变形都应该属于本发明权利要求的保护范围之内。 [0020] to those skilled in the art, the technical solution according to the above described and contemplated, that various other changes and modifications appropriate, and all such changes and modifications should fall into the scope of the claims of the invention within.

Claims (5)

1.全自动双轨道冷冻切片染色仪,包括箱体,自动控制系统以及设置在所述箱体中的试剂缸,其特征在于:在所述箱体两侧的长边方向分别设有第一导轨和第二导轨,所述第一导轨和第二导轨上分别设有第一染色装置和第二染色装置。 1. Automatic two-track cryosections stainer, includes a case, an automatic control system, and a reagent disposed in said case cylinder, wherein: the first are provided in the longitudinal direction of the housing sides and second rails, respectively provided with first and second means dyeing means dyeing said first and second rails.
2.根据权利要求I所述的染色仪,其特征在于:所述第一染色装置包括底座,与所述底座电气连接的伺服电机,染色气缸,以及第一机械臂,所述气缸设置在所述底座的顶部,所述第一机械臂设置在所述气缸上,所述第一机械臂前端设有挂钩,所述底座设有与第一导轨相匹配的滚轮。 The stainer I according to claim, wherein: said first means includes a servo motor mount staining, and electrically connected to the base, dyeing cylinder, and a first robot arm provided by the cylinder the top of said base, the first robot arm provided on said cylinder, the front end of the robot arm is provided with a first hook, the base is provided with a first guide roller matches.
3.根据权利要求I所述的染色仪,其特征在于:所述第二染色装置包括底座,与所述底座电气连接的伺服电机,染色气缸,以及第二机械臂,所述气缸设置在所述底座的顶部,所述第二机械臂设置在所述气缸上,所述第二机械臂前端设有挂钩,所述底座设有与第二导轨相匹配的滚轮。 According to claim I of the stainer, wherein: said second means includes a servo motor mount staining, and electrically connected to the base, dyeing cylinder, and a second arm, being provided on the cylinder the top of said base, a second arm provided on said cylinder, with the front end of the second arm link, the base is provided with a second guide roller matches.
4.根据权利要求I所述的染色仪,其特征在于:所述试剂缸顶部设有开合部件,所述开合部件由开盖、转动拉杆以及开合气缸组成,其中,所述转动拉杆的一端与开盖活动连接,其另一端连接于气缸。 According to claim I of the stainer, wherein: said cylinder is provided with a top closure member reagent, the closure member from the open end, and an opening closing cylinder rod is rotated, where the rotation of the rod the lid opening and movably connected at one end, the other end connected to the cylinder.
5.根据权利要求I或4所述的染色仪,其特征在于:所述试剂缸设有5-25个。 I according to claim 4 or claim stainer, wherein: said cylinder is provided with reagent 5-25.
CN2012103779418A 2012-09-29 2012-09-29 Fully-automatic double-rail staining instrument for frozen sections CN102854050A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103207106A (en) * 2013-04-24 2013-07-17 梁建中 Turntable type frozen slice dyeing machine
WO2018145386A1 (en) * 2017-02-08 2018-08-16 爱威科技股份有限公司 Sample staining device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103207106A (en) * 2013-04-24 2013-07-17 梁建中 Turntable type frozen slice dyeing machine
WO2018145386A1 (en) * 2017-02-08 2018-08-16 爱威科技股份有限公司 Sample staining device

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