CN111808923A - Gene detection method and device - Google Patents

Gene detection method and device Download PDF

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Publication number
CN111808923A
CN111808923A CN202010701174.6A CN202010701174A CN111808923A CN 111808923 A CN111808923 A CN 111808923A CN 202010701174 A CN202010701174 A CN 202010701174A CN 111808923 A CN111808923 A CN 111808923A
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gene
culture dish
box
fixedly connected
gene detection
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CN111808923B (en
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魏瑷琳
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West China Hospital of Sichuan University
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West China Hospital of Sichuan University
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/36Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by using brushes

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  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention belongs to the technical field of biological engineering, and particularly relates to a gene detection method, which comprises the following steps: detect and prepare, add reagent, upset and wash, the device that uses in the gene testing process includes the box, box sliding connection has the apron, apron fixedly connected with liquid supply box, the box is equipped with the baffle, the baffle can be dismantled and be connected with the multiunit culture dish, liquid supply box and culture dish cooperation set up, the culture dish passes through tilting mechanism and baffle swing joint, box fixedly connected with driving motor, driving motor's output shaft has wiper mechanism through driving medium swing joint, wiper mechanism and box sliding connection, wiper mechanism and tilting mechanism transmission are connected. The invention can realize the integral automatic reagent adding work of the culture dish, reduce the labor intensity of manual operation of workers, improve the gene detection efficiency, and meanwhile, the device has the automatic cleaning function and is suitable for popularization in a range.

Description

Gene detection method and device
Technical Field
The invention belongs to the technical field of biological engineering, and particularly relates to a gene detection method and a gene detection device.
Background
The gene detection is a technique for detecting DNA by blood, other body fluids or cells, and is a method for detecting DNA molecular information in cells of a detected person by a specific device after the peripheral venous blood or other tissue cells of the detected person are amplified, and analyzing whether the gene type, the gene defect and the expression function contained in the DNA molecular information are normal or not. Gene detection is one of the detection methods commonly used in bioengineering, but as the detection requirements of bioengineering are continuously improved, the defects of gene detection work in the actual operation process are urgently needed to be perfected.
In the prior art, most of gene detection work in bioengineering still adds reagent through artifical manual mode, increases the intensity of labour that the staff operated, especially when facing big batch detection sample, need consume a large amount of manpower and materials, reduces gene detection work efficiency, and the culture dish cleaning work after the completion of detecting simultaneously is comparatively complicated, is not convenient for putting into use rapidly of culture dish, reduces the utilization of resources of equipment.
Therefore, we propose a gene detection method and apparatus thereof to solve the above problems.
Disclosure of Invention
The invention aims to solve the problems, and provides a gene detection method and a gene detection device which can automatically add a reagent to improve the detection efficiency, can realize automatic cleaning after gene detection is finished, and can quickly carry out secondary use on a culture dish.
In order to achieve the purpose, the invention adopts the following technical scheme:
a gene detection method mainly comprises the following steps:
s1 detection preparation: stably placing a container for storing a gene sample to be detected through the device, and carrying out preparation work of gene detection;
s2 reagent addition: integrally and automatically adding a reagent into the stably placed gene sample by a mechanical means, and performing gene detection;
s3 turning: after the gene detection work of S2 is finished, the container for storing the gene sample is directly turned over by the device, so that the cleaning work of the container is facilitated;
s4 cleaning: the turned gene detection container is cleaned by rotation so as to facilitate subsequent detection work.
Still adopted a gene detection device, the power distribution box comprises a box body, box sliding connection has the apron, apron fixedly connected with liquid supply box, the box is equipped with the baffle, the baffle can be dismantled and be connected with the multiunit culture dish, liquid supply box and culture dish cooperation setting, the culture dish passes through tilting mechanism and baffle swing joint, box fixedly connected with driving motor, driving motor's output shaft has wiper mechanism through driving medium swing joint, wiper mechanism and box sliding connection, wiper mechanism and tilting mechanism transmission are connected.
In the gene detection device, one end of the cover plate is fixedly connected with the handle, the other end of the cover plate is symmetrically provided with the sliding blocks, the box body is provided with the sliding groove, and the sliding blocks are in rolling connection with the sliding groove through the rolling balls.
In the gene detection device, the cover plate is provided with a water distribution pipe, one end of the water distribution pipe is communicated with the liquid supply tank, the other end of the water distribution pipe is matched with the culture dish through a rubber taper pipe, and the rubber taper pipe is positioned right above the culture dish.
In foretell gene testing device, the feed tank includes feed tank and reagent box, feed tank and reagent box all set up through transfer line and water distributor intercommunication, the one end that the feed tank was kept away from to the box is equipped with the drain pipe, drain pipe and transfer line all are equipped with control flap.
In foretell gene testing device, the baffle adopts circular structure, the baffle is equipped with the multiunit and places the hole, the culture dish with place the hole cooperation and connect, the one end that the box is close to the baffle is equipped with the heater, the other end that the box is close to the baffle is equipped with ultraviolet lamp, the box is equipped with the observation window.
In the above gene detection device, the turnover mechanism includes a rotating shaft, a toothed ring and a clamping member, the rotating shaft is rotatably connected with the box body, the rotating shaft at one end of the toothed ring is fixedly connected, and the other end of the toothed ring is movably connected with the clamping member through a first gear.
In the above gene detection device, the clamping member includes a guide rod, a sleeve and a clamping block, one end of the guide rod is fixedly connected with the first gear, the other end of the guide rod is slidably connected with the sleeve through a spring, the sleeve is fixedly connected with the clamping block, the culture dish is provided with a cross groove, and the clamping block is connected with the cross groove in a matching manner.
In the above gene detection device, the sleeve is provided with a limiting groove, the guide rod is provided with a limiting block, and the limiting block is slidably connected with the limiting groove.
In the above gene detection device, the cleaning mechanism comprises a support frame and cleaning cotton, the cleaning cotton is rotatably connected with the support frame through a cleaning motor, and the support frame is in threaded connection with the rotating shaft through a threaded sleeve.
In the above gene detection device, the transmission member includes a second gear and a rack that are engaged with each other, the second gear is fixedly connected with an output shaft of the driving motor, one end of the support frame is fixedly connected with the rack, and the other end of the support frame is slidably connected with the box body through a telescopic rod.
Compared with the prior art, the gene detection method and the device thereof have the advantages that:
1. according to the gene detection method and the device thereof, the liquid supply box is arranged, and the culture dish on the partition plate is matched for automatically adding the reagent, so that a worker does not need to manually add the reagent for detection in the gene detection work of the bioengineering, the gene detection efficiency is effectively improved, the labor intensity of the worker in operation is reduced, and the gene detection method and the device are suitable for popularization.
2. According to the gene detection method and the device, the cover plate is arranged, so that the device can perform sealing work in the gene detection process, and the liquid supply box is matched for integrally adding the reagent, so that the influence degree of foreign matters such as dust and bacteria in the air in the culture dish detection process on the gene detection is effectively reduced, the gene detection accuracy is improved, and the practicability of the device is improved.
3. According to the gene detection method and the device, the turnover mechanism is arranged, so that the culture dish automatically turns over after the gene detection work is finished, the cleaning mechanism is matched for cleaning the culture dish, workers do not need to clean in a disassembly and cleaning mode, the culture dish can be rapidly reused, the resource utilization of the device is effectively improved, the gene detection efficiency is improved, meanwhile, the contact between the workers and a gene sample is avoided, and the safety of the gene detection is improved.
Drawings
FIG. 1 is a schematic view of the flow structure of a gene detection method provided by the present invention;
FIG. 2 is a schematic view showing the external structure of a gene assaying device according to the present invention;
FIG. 3 is a schematic view of the internal structure of a gene assaying device according to the present invention;
FIG. 4 is an enlarged schematic view at A in FIG. 3;
FIG. 5 is an enlarged schematic view at B in FIG. 3;
FIG. 6 is a schematic view showing the structure of a partition plate in the gene assaying device according to the present invention.
In the figure, 1 a box body, 11 chutes, 12 water discharge pipes, 13 heaters, 14 ultraviolet lamps, 15 observation windows, 2 cover plates, 21 handles, 22 sliders, 221 balls, 23 water distribution pipes, 24 rubber taper pipes, 3 liquid supply tanks, 31 water supply tanks, 32 reagent tanks, 33 liquid conveying pipes, 34 control valves, 4 partition plates, 41 placement holes, 5 culture dishes, 51 cross grooves, 6 turnover mechanisms, 61 rotating shafts, 62 toothed rings, 63 clamping pieces, 631 guide rods, 632 sleeves, 633 clamping blocks, 634 springs, 64 first gears, 7 driving motors, 8 transmission pieces, 81 second gears, 82 racks, 9 cleaning mechanisms, 91 support frames, 92 cleaning cotton, 93 cleaning motors, 94 thread sleeves and 95 telescopic rods.
Detailed Description
The following examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
As shown in FIG. 1, a gene detection method mainly comprises the following steps:
s1 detection preparation: stably placing a container for storing a gene sample to be detected through the device, and carrying out preparation work of gene detection;
s2 reagent addition: integrally and automatically adding a reagent into the stably placed gene sample by a mechanical means, and performing gene detection;
s3 turning: after the gene detection work of S2 is finished, the container for storing the gene sample is directly turned over by the device, so that the cleaning work of the container is facilitated;
s4 cleaning: the turned gene detection container is cleaned by rotation so as to facilitate subsequent detection work.
The detection method can directly clean the container by overturning and cleaning after the gene sample container finishes gene detection work, avoids manual collection and cleaning of workers, improves the work efficiency of the gene detection process, reduces the contact between the workers and the gene sample, and improves the safety of gene detection.
As shown in fig. 2-6, a gene detection device comprises a box body 1, a cover plate 2 is slidably connected to the box body 1, it should be noted that a handle 21 is fixedly connected to one end of the cover plate 2, so that an operator can conveniently open and close the box body 1, sliders 22 are symmetrically arranged at the other end of the cover plate 2, a chute 11 is arranged on the box body 1, and the sliders 22 are in rolling connection with the chute 11 through balls 221, so that the friction coefficient of the cover plate 2 in the opening and closing process is reduced.
2 fixedly connected with liquid supply tank 3 of apron, box 1 are equipped with baffle 4, and baffle 4 can be dismantled and be connected with multiunit culture dish 5, and liquid supply tank 3 and culture dish 5 cooperation set up.
Specifically, apron 2 is equipped with water distributor 23, and the one end and the 3 intercommunication settings of feed tank of water distributor 23, the other end of water distributor 23 pass through rubber taper pipe 24 and the cooperation setting of culture dish 5, and rubber taper pipe 24 is located culture dish 5 directly over for the device can carry out integral automatic reagent work of adding, need not the staff and carries out detection achievement through the mode of manual reagent that adds, effectively improves gene detection efficiency.
More specifically, the liquid supply tank 3 comprises a water supply tank 31 and a reagent tank 32, the water supply tank 31 and the reagent tank 32 are both communicated with the water distribution pipe 23 through a liquid conveying pipe 33, a water discharging pipe 12 is arranged at one end of the tank body 1 far away from the liquid supply tank 3, the water discharging pipe 12 and the liquid conveying pipe 33 are both provided with control valves 34, it should be noted that the water supply tank 31 is used for storing cleaning liquid, and the reagent tank 32 is used for storing detection reagent, so that the device can be cleaned and detected conveniently.
Baffle 4 adopts circular structure, baffle 4 is equipped with the multiunit and places hole 41, culture dish 5 with place hole 41 cooperation and connect, the one end that box 1 is close to baffle 4 is equipped with heater 13, it needs to explain, heater 13 adopt common heater on the market can, make box 1 carry out normal detection achievement under the lower operational environment of temperature, box 1 is close to the other end of baffle 4 and is equipped with ultraviolet lamp 14, ultraviolet lamp 14 is used for the device to the disinfection and sterilization work of culture dish 5 clean in-process after detecting the completion, guarantee the sterile environment of box 1 and culture dish 5, be convenient for the continuous detection achievement of device, box 1 is equipped with observation window 15, observation window 15 and box 1 can dismantle the connection, be convenient for staff's observation work, be used for wiper mechanism 9's change work simultaneously.
The culture dish 5 is movably connected with the partition board 4 through a turnover mechanism 6, and the specific movable connection process is as follows: tilting mechanism 6 includes pivot 61, ring gear 62 and clamping piece 63, and pivot 61 rotates through bearing and box 1 and is connected, and the one end of ring gear 62 is through support pivot 61 fixed connection, and the one end and the first gear 64 meshing connection of ring gear 62 far away from pivot 61, first gear 64 and clamping piece 63 swing joint.
More specifically, clamping member 63 includes guide arm 631, sleeve 632 and clamp piece 633, the one end and the first gear 64 fixed connection of guide arm 631, the other end of guide arm 631 passes through spring 634 and sleeve 632 sliding connection, guide arm 631 is equipped with the stopper, sleeve 632 is equipped with the spacing groove, stopper and spacing groove sliding connection, it can not appear rotating in the normal clamping operation to guarantee to press from both sides tight piece 633, sleeve 632 and clamp piece 633 fixed connection, culture dish 5 is equipped with cross recess 51, press from both sides tight piece 633 and cross recess 51 cooperation connection, it needs to be noted that, press from both sides tight piece 633 and adopt cross structure, improve the stability of culture dish 5 clamping process, the one end that culture dish 5 kept away from guide arm 631 is fixed through the clamp piece 633 who rotates the connection, improve the steadiness in the culture dish 5 detection work.
The box body 1 is fixedly connected with a driving motor 7, an output shaft of the driving motor 7 is movably connected with a cleaning mechanism 9 through a transmission piece 8, the cleaning mechanism 9 is in sliding connection with the box body 1, and the cleaning mechanism 9 is in transmission connection with the turnover mechanism 6.
Specifically, wiper mechanism 9 includes support frame 91 and washs cotton 92, it rotates through washing motor 93 and support frame 91 to wash cotton 92 and connect, washing motor 93 adopts the model to be ZGA37RG micro motor, wash cotton 92 and the output shaft detachable connection of washing motor 93, be convenient for the staff regularly changes and washs cotton 92, the clean effect of assurance device use, support frame 91 passes through thread bush 94 and pivot 61 threaded connection, pivot 61 only local position is equipped with the external screw thread, make culture dish 5 wash cotton 92 and can continuously rise after the upset is accomplished, until with culture dish 5 contact laminating, improve culture dish 5's clean effect, it adopts bilayer structure to wash cotton 92, be convenient for absorb cleaning work to the cleaning solution that the feed water tank 31 flows.
More specifically, box 1 is equipped with the activity groove, driving motor 7 and activity groove 1 fixed connection, driving motor 7 adopts the model to be SJGB-57 gear motor, driving medium 8 includes intermeshing's second gear 81 and rack 82, second gear 81 and driving motor 7's output shaft fixed connection, the one end and the rack 82 fixed connection of support frame 91, the other end of support frame 91 passes through telescopic link 95 and box 1 sliding connection, improves the stability of support frame 91 lift in-process.
The operating principle of the present invention will now be described as follows:
when the invention is used, a worker places the culture dish 5 which is sampled in the placing hole 41 of the partition plate 4, the clamping operation is carried out through the clamping block 633, the sleeve 632 slides through the spring 634 and the guide rod 631 in the clamping process of the culture dish 5, the clamping block 633 is matched with the cross groove 51 to clamp and fix the culture dish 5, the stability of the culture dish 5 in the detection operation is ensured, after the culture dish 5 is placed, the cover plate 2 is pulled through the handle 21 to carry out certain sealing operation on the culture dish 5, the degree of gene detection caused by foreign matters such as dust, bacteria and the like in the air is avoided, and at the moment, the slide block 22 fixedly connected with the cover plate 2 slides through the ball 221 and the chute 11, so that the preparation operation of the gene detection is completed. Open the transfer line 33 of reagent case 32 through control valve 34 for the detect reagent in the reagent case 32 drips into culture dish 5 through rubber taper pipe 24 through water distributor 23 and carries out integral reagent interpolation work, closes control valve 34 after reagent interpolation is accomplished, and then expandes culture dish 5's gene detection work, and the staff can pass through the inside detection temperature of heater 13 adjustment box 1 according to the detection demand in the testing process, improves the detection effect of device. After the gene detection work is completed, the power supply is started, the driving motor 7 drives the meshed rack 82 to move through the second gear 81, the rack 82 drives the support frame 91 to ascend, at the moment, one end, far away from the rack 82, of the support frame 91 slides through the telescopic rod 95 and the box body 1, the threaded sleeve 94 drives the rotating shaft 61 to rotate through the external thread of the rotating shaft 61 in the ascending process of the support frame 91, the toothed ring 62 fixedly connected with the rotating shaft 61 drives the guide rod 631 to rotate through the first gear 64, the guide rod 631 drives the culture dish 5 to turn over through the clamping block 633, the control valve 34 of the water supply box 31 is opened, so that the cleaning solution can perform infusion work on the culture dish 5 through the rubber cone 24, the liquid is absorbed by the cleaning cotton 92 under flowing, the cleaning work can be performed on the culture dish 5 through the driving of the cleaning cotton 92 through the rotation of the cleaning motor 93, and the, in the cleaning process, ultraviolet lamp 14 carries out certain disinfection and sterilization work to box 1 and culture dish 5, guarantees the sterile environment of box 1 and culture dish 5, makes culture dish 5 overturn and replies the east action under driving motor 7's drive after accomplishing the cleaning work, and the staff changes or continuously uses culture dish 5 according to the user demand, improves the detection efficiency of device.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (10)

1. A gene detection method is characterized by mainly comprising the following steps:
s1 detection preparation: stably placing a container for storing a gene sample to be detected through the device, and carrying out preparation work of gene detection;
s2 reagent addition: integrally and automatically adding a reagent into the stably placed gene sample by a mechanical means, and performing gene detection;
s3 turning: after the gene detection work of S2 is finished, the container for storing the gene sample is directly turned over by the device, so that the cleaning work of the container is facilitated;
s4 cleaning: the turned gene detection container is cleaned by rotation so as to facilitate subsequent detection work.
2. The utility model provides a gene detection device, its characterized in that, includes box (1), box (1) sliding connection has apron (2), apron (2) fixedly connected with liquid supply tank (3), box (1) is equipped with baffle (4), baffle (4) can be dismantled and be connected with multiunit culture dish (5), liquid supply tank (3) and culture dish (5) cooperation setting, culture dish (5) are through tilting mechanism (6) and baffle (4) swing joint, box (1) fixedly connected with driving motor (7), the output shaft of driving motor (7) has wiper mechanism (9) through driving medium (8) swing joint, wiper mechanism (9) and box (1) sliding connection, wiper mechanism (9) and tilting mechanism (6) transmission are connected.
3. The gene detecting device according to claim 2, wherein one end of the cover plate (2) is fixedly connected with a handle (21), the other end of the cover plate (2) is symmetrically provided with sliding blocks (22), the box body (1) is provided with a sliding groove (11), and the sliding blocks (22) are connected with the sliding groove (11) in a rolling manner through balls (221).
4. The gene detecting device according to claim 2, wherein the cover plate (2) is provided with a water distribution pipe (23), one end of the water distribution pipe (23) is communicated with the liquid supply tank (3), the other end of the water distribution pipe (23) is matched with the culture dish (5) through a rubber taper pipe (24), and the rubber taper pipe (24) is positioned right above the culture dish (5).
5. The gene detecting device according to claim 4, wherein the liquid supply tank (3) comprises a water supply tank (31) and a reagent tank (32), the water supply tank (31) and the reagent tank (32) are both communicated with the water distribution pipe (23) through a liquid conveying pipe (33), a water discharging pipe (12) is arranged at one end of the tank body (1) far away from the liquid supply tank (3), and the water discharging pipe (12) and the liquid conveying pipe (33) are both provided with a control valve (34).
6. The gene detecting device according to claim 2, wherein the partition board (4) is of a circular structure, the partition board (4) is provided with a plurality of sets of placing holes (41), the culture dish (5) is matched and connected with the placing holes (41), one end of the box body (1) close to the partition board (4) is provided with the heater (13), the other end of the box body (1) close to the partition board (4) is provided with the ultraviolet lamp (14), and the box body (1) is provided with the observation window (15).
7. The gene detecting device according to claim 2, wherein the turnover mechanism (6) comprises a rotating shaft (61), a gear ring (62) and a clamping member (63), the rotating shaft (61) is rotatably connected with the box body (1), one end of the gear ring (62) is fixedly connected with the rotating shaft (61), and the other end of the gear ring (62) is movably connected with the clamping member (63) through a first gear (64).
8. The gene detecting device according to claim 7, wherein the clamping member (63) comprises a guide rod (631), a sleeve (632) and a clamping block (633), one end of the guide rod (631) is fixedly connected with the first gear (64), the other end of the guide rod (631) is slidably connected with the sleeve (632) through a spring (634), the sleeve (632) is fixedly connected with the clamping block (633), the culture dish (5) is provided with a cross groove (51), and the clamping block (633) is in fit connection with the cross groove (51).
9. The gene detecting device according to claim 6, wherein the cleaning mechanism (9) comprises a support frame (91) and cleaning cotton (92), the cleaning cotton (92) is rotatably connected with the support frame (91) through a cleaning motor (93), and the support frame (91) is in threaded connection with the rotating shaft (61) through a threaded sleeve (94).
10. The gene detecting device according to claim 9, wherein the transmission member (8) comprises a second gear (81) and a rack (82) which are engaged with each other, the second gear (81) is fixedly connected with an output shaft of the driving motor (7), one end of the supporting frame (91) is fixedly connected with the rack (82), and the other end of the supporting frame (91) is slidably connected with the box body (1) through a telescopic rod (95).
CN202010701174.6A 2020-07-20 2020-07-20 Gene detection method and device Active CN111808923B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113073049A (en) * 2021-04-21 2021-07-06 河南亚都实业有限公司 Bioreactor for artificial skin tissue culture

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CN110894460A (en) * 2019-11-24 2020-03-20 南通市第一人民医院 Anti-pollution formula bacteria culture device of clinical laboratory
CN110951602A (en) * 2019-12-06 2020-04-03 王佳琪 Biological medicine culture dish
CN210528953U (en) * 2019-06-14 2020-05-15 上海君实生物医药科技股份有限公司 Kit for biological cell culture

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Publication number Priority date Publication date Assignee Title
CN107338190A (en) * 2017-07-26 2017-11-10 青岛市海慈医疗集团 A kind of clinical laboratory's anti-pollution type germ culturing device
CN110157605A (en) * 2018-04-16 2019-08-23 青岛瑞思德生物科技有限公司 A kind of bioengineering gene assaying device
CN208960548U (en) * 2018-08-13 2019-06-11 杭州木木生物科技有限公司 A kind of Plant Tissue Breeding ware chlorination equipment
CN210528953U (en) * 2019-06-14 2020-05-15 上海君实生物医药科技股份有限公司 Kit for biological cell culture
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Publication number Priority date Publication date Assignee Title
CN113073049A (en) * 2021-04-21 2021-07-06 河南亚都实业有限公司 Bioreactor for artificial skin tissue culture

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