CN115317731A - Device for stable injection of lateral ventricle of animal experiment - Google Patents
Device for stable injection of lateral ventricle of animal experiment Download PDFInfo
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- CN115317731A CN115317731A CN202210479931.9A CN202210479931A CN115317731A CN 115317731 A CN115317731 A CN 115317731A CN 202210479931 A CN202210479931 A CN 202210479931A CN 115317731 A CN115317731 A CN 115317731A
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- injection
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- fixing plate
- animal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/427—Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a device for lateral stable brain injection in animal experiments, which relates to the technical field of animal experiment injection equipment and comprises a rail frame, wherein a positioning assembly is arranged in the middle of the rail frame, scale marks are arranged on the inner side of the upper surface of the rail frame, a supporting mechanism consists of a sliding block, a supporting rod and a fixing plate, the upper surface of the sliding block is connected with the lower surface of the supporting rod, the upper end of the supporting rod is connected with the lower end of the fixing plate, an indicating needle is arranged in the middle of the inner side of the supporting rod, an arc rod facing outwards is arranged at the upper end of the indicating needle, evenly distributed angle lines are arranged on the arc rod, and the fixing plate is obliquely arranged at the upper end of the supporting rod. In the using process, the rapid and accurate injection to the lateral cerebral ventricle in the animal experiment process is improved through the position data of the animal head relative to the positioning component, the data of the angle line and the coincidence angle of the fixed plate and the data of the pointer pointing to the scale mark.
Description
Technical Field
The invention relates to the technical field of animal experiment injection equipment, in particular to a device for stable injection of lateral ventricles of an animal experiment.
Background
The final aim of the scientific development of experimental animals is to promote the life of human beings by researching the life phenomena of the animals and prolong the life of the human beings. With the rapid development of medical science and bioscience, it is recognized that the public hazard problem not only becomes a serious social problem of food, population, the elderly, etc., but also relates to the survival problem of animals living on the earth, such as industrial hazard, food hazard, drug toxicity, etc., which directly affect human health, and the research on the problems is finally inevitably solved through animal experiments (including the development of animal disease models, etc.).
When the lateral ventricle injection of an animal experiment is carried out, the injection is finished by adopting an injector to hold the injector in hand in the existing operation mode, and the specific injection position in the injection process is judged by the injector according to experience, so the lateral ventricle injection device has the following defects: firstly, when the same animal is injected for multiple times and the injection personnel are different, the injection position fails due to different injection experiences, and further the failure of the whole experiment process is caused; secondly, when the same animal performs lateral ventricle injection on two sides, the injection personnel needs to operate by experience, and rapid injection on the other side cannot be performed according to the lateral ventricle injection result on one side. To this end, we propose a device for stable intracerebroventricular injection in animals for experimental work.
Disclosure of Invention
The invention aims to solve the defects in the prior art, and provides the device for stable lateral ventricle injection in the animal experiment, which can complete the lateral ventricle injection of animals according to a mode of directly reading data when injecting the same animal and different injectors in the whole injection process, can complete the rapid injection without being influenced by injection experience, and is convenient to operate; when carrying out the injection of different animals, can inject after judging animal side ventricle position through locating component, and can use supporting mechanism to support the syringe body in the quick adjustment shift position of rail frame among the injection process, the injection is comparatively accurate.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a device that is used for animal experiment side ventricle to stabilize injection, includes the rack, the middle part of rack is provided with locating component, evenly distributed's scale mark is seted up to the inboard of rack upper surface, slidable mounting has supporting mechanism on the rack, supporting mechanism comprises slider, bracing piece and fixed plate, the upper surface of slider is connected with the lower surface of bracing piece, the upper end of bracing piece is connected with the lower extreme of fixed plate, the inboard mid-mounting of bracing piece has the pointer, the upper end fixed mounting of pointer has the arc pole towards the outside, set up evenly distributed's angle line on the arc pole, the fixed plate is the slope and sets up in the upper end of bracing piece, one side upper end fixed mounting that the fixed plate was kept away from to the bracing piece has arc shell fragment, the upper end fixed mounting that arc shell fragment is close to bracing piece one side has the syringe body, the lower extreme fixed mounting of syringe body has the pjncture needle, the one end that the pjncture needle was kept away from to the syringe body is inserted and is established and is installed the propelling movement pole.
Preferably, the upper end of the arc rod penetrates through the fixing plate and extends to the upper part, and the upper end of the arc rod and the inner side of the arc-shaped elastic sheet are close to each other but not in contact.
Preferably, an arc plate is fixedly mounted on the inner side of the upper end of the arc-shaped elastic sheet, and the upper surface of the arc plate is connected with the lower end of the outer annular surface of the injector body.
Preferably, the middle part of the upper surface of the rail frame is provided with a sliding groove, and the sliding block is matched with the sliding groove.
Preferably, the magnifying lens ring is fixedly mounted on the inner side of one end, away from the supporting rod, of the fixing plate, and the plate body part, corresponding to the magnifying lens ring, of the fixing plate is in an opening shape.
Preferably, the pointer corresponds to a graduation mark.
Preferably, the puncture needle corresponds to the opening on the fixing plate.
Preferably, one end, far away from the supporting rod, of the fixing plate is in a semicircular shape, and the fixing plate is made of an aluminum plate.
Preferably, the injector body is made of an iron material, the arc plate is made of a magnet, and the arc plate is connected with the iron material in an attracting mode.
The invention provides a device for stable injection of lateral ventricles of an animal experiment, which has the beneficial effects that:
this technical scheme is at the in-process of using, under the condition that has accomplished the side ventricle to animal head one side and inject, when injecting the side ventricle to the animal opposite side, the side ventricle based on animal is the symmetric distribution, under the unchangeable condition of angle coincidence data, based on the data of the directional scale mark record of pointer, remove the slider to the symmetric position department of the rail frame other end, can directly carry out the injection to animal opposite side ventricle this moment, and then realized the quick injection to animal both sides side ventricle.
When the injection needs to be tested for the same animal for multiple times, the application reference can be carried out according to the position data of the animal head relative positioning assembly, the angle line and fixed plate coincidence angle data and the data of the pointer pointing to the scale mark recorded in the first injection process, so that the subsequent multiple injections can be carried out quickly, the success rate of the injection can still be ensured under the condition of different experiences of injection personnel, and the injection is favorable for popularization and use.
Drawings
FIG. 1 is a schematic structural diagram of a device for stable lateral ventricle injection in an animal experiment according to the present invention;
FIG. 2 is a schematic diagram of a disassembled structure of a device for stable lateral ventricle injection in an animal experiment, which is provided by the invention;
FIG. 3 is a schematic structural diagram of an injection mechanism of the device for stable lateral ventricle injection in an animal experiment according to the present invention;
FIG. 4 is a schematic structural diagram of a supporting mechanism of the device for stable lateral ventricle injection in an animal experiment provided by the invention;
FIG. 5 is a schematic view of the injector body of the device for stable lateral ventricle injection in an animal experiment according to the present invention;
fig. 6 is a structural sectional view of a rail frame of the device for lateral stable ventricular injection in an animal experiment.
In the figure: 1. a rail frame; 2. a slider; 3. a support bar; 4. scale lines; 5. an arc-shaped elastic sheet; 6. an arc plate; 7. an injector body; 8. puncturing needle; 9. a fixing plate; 10. a magnifier ring; 11. a push rod; 12. an arc rod; 13. a chute; 14. an indicator needle; 15. an angle line; 16. and a positioning component.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example 1
Referring to fig. 1-6, a device for stable injection of animal experiment lateral ventricle, includes rail frame 1, and the middle part of rail frame 1 is provided with locating component 16, and evenly distributed's scale mark 4 is seted up to the inboard of rail frame 1 upper surface, and slidable mounting has a supporting mechanism on rail frame 1, and the supporting mechanism comprises slider 2, bracing piece 3 and fixed plate 9, and the upper surface of slider 2 is connected with the lower surface of bracing piece 3, and the upper end of bracing piece 3 is connected with the lower extreme of fixed plate 9.
The slide block 2 moves in the sliding groove 13 on the rail frame 1, so as to drive the whole composed of the support rod 3 and the fixing plate 9 to move, and further realize the movement of the injector body 7.
The utility model discloses a syringe, including bracing piece 3, the inboard mid-mounting of bracing piece has pointer 14, the upper end fixed mounting of pointer 14 has arc pole 12 towards the outside, set up evenly distributed's angle line 15 on arc pole 12, fixed plate 9 is the slope and sets up in the upper end of bracing piece 3, one side upper end fixed mounting that fixed plate 9 was kept away from to bracing piece 3 has arc shell fragment 5, arc shell fragment 5 is close to the upper end fixed mounting on bracing piece 3 one side has syringe body 7, the lower extreme fixed mounting of syringe body 7 has pjncture needle 8, syringe body 7 is kept away from the one end of pjncture needle 8 and is inserted and establish and install push rod 11, change the inclination of syringe body 7 through the arc shell fragment 5 that can pull, thereby the concrete puncture position of adaptation animal side ventricle, make pjncture needle 8 on the syringe body 7 correspond the magnifying glass ring 10 on the fixed plate 9, it is located magnifying glass ring 10 to reach puncture in-process pjncture needle 8, and convenient to operate.
Fixed plate 9 is run through and extends to the upper side in the upper end of arc pole 12, be close to each other but contactless between the upper end of arc pole 12 and the inboard of arc shell fragment 5, inboard fixed mounting of arc shell fragment 5 upper end has arc board 6, the upper surface of arc board 6 is connected with the outer anchor ring lower extreme of syringe body 7, spout 13 has been seted up at the middle part of 1 upper surface of track frame, slider 2 and spout 13 phase-match, the inboard fixed mounting that bracing piece 3 one end was kept away from to fixed plate 9 has magnifier ring 10, the plate body part that fixed plate 9 corresponds magnifier ring 10 is the opening form, magnifier ring 10's setting, when the animal head outside is arranged in to pjncture needle 8 of being convenient for, accomplish the picture amplification to puncture needle 8 through magnifier ring 10, the experimenter of being convenient for observes, accurate definite puncture position.
In the invention, when the device is used for injecting the lateral ventricle of an animal experiment, the head of the animal is rested on the positioning component 16 in the middle of the rail frame 1 after the animal is completely numb, the head of the animal is relatively positioned on the positioning component 16 and the position is recorded according to the specific position of the head of the animal on the positioning component 16, the position of the slide block 2 in the chute 13 is moved according to the specific position of the lateral ventricle of the animal, and when the injector body 7 on the arc-shaped elastic sheet 5 points to the lateral ventricle of the animal, the number pointing to the scale mark 4 according to the indicating needle 14 is recorded;
then slightly adjusting the relative position between the injector body 7 and the magnetic arc plate 6, simultaneously adjusting the inclination angle between the fixing plate 9 and the supporting rod 3, recording the coincidence angle data of the angle line 15 on the arc rod 12 and the fixing plate 9, and ensuring that the middle part of the magnifier ring 10 is aligned with the part to be injected on one side of the ventricles of the animal side, under the condition, the puncture needle 8 on the injector body 7 penetrates through the middle part of the magnifier ring 10 and punctures into the ventricles of the animal side, and the injection can be completed through the injector body 7;
immediately, under the condition of injecting the ventricles on the other side of the animal, the ventricles on the side of the animal are symmetrically distributed, under the condition of keeping the angle coincidence data unchanged, the slide block 2 is moved to the symmetrical position at the other end of the rail frame 1 based on the data recorded by the pointer 14 pointing to the scale mark 4, and at the moment, the ventricles on the other side of the animal can be directly injected, so that the rapid injection of the ventricles on the two sides of the animal is realized;
when the same animal needs to be subjected to multiple experimental injections, the application reference can be carried out according to the position data of the animal head relative positioning assembly 16, the coincidence angle data of the angle line 15 and the fixing plate 9 and the data of the indicating needle 14 pointing to the scale mark 4 recorded in the first injection process, so that the subsequent multiple injections can be carried out quickly, the success rate of the injections can still be ensured under the condition of different experiences of injection personnel, and the popularization and the use are facilitated.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered as the technical solutions and the inventive concepts of the present invention within the technical scope of the present invention.
Claims (9)
1. A device for stable injection of lateral ventricles of an animal experiment comprises a rail frame (1), it is characterized in that the middle part of the rail frame (1) is provided with a positioning component (16), the inner side of the upper surface of the rail frame (1) is provided with evenly distributed scale marks (4), the rail frame (1) is provided with a supporting mechanism in a sliding way, the supporting mechanism consists of a sliding block (2), a supporting rod (3) and a fixing plate (9), the upper surface of the sliding block (2) is connected with the lower surface of the supporting rod (3), the upper end of the supporting rod (3) is connected with the lower end of the fixing plate (9), the middle part of the inner side of the support rod (3) is provided with an indicating needle (14), the upper end of the indicator needle (14) is fixedly provided with an arc rod (12) which faces outwards, the arc rod (12) is provided with evenly distributed angle lines (15), the fixing plate (9) is obliquely arranged at the upper end of the supporting rod (3), the upper end of one side of the support rod (3) far away from the fixing plate (9) is fixedly provided with an arc-shaped elastic sheet (5), the upper end of one side of the arc-shaped elastic sheet (5) close to the support rod (3) is fixedly provided with an injector body (7), the lower end of the injector body (7) is fixedly provided with a puncture needle (8), and a pushing rod (11) is inserted and installed at one end, far away from the puncture needle (8), of the injector body (7).
2. The device for lateral ventricle stabilization injection of animal experiments according to claim 1, wherein the upper end of the arc rod (12) penetrates through the fixing plate (9) and extends to the upper side, and the upper end of the arc rod (12) and the inner side of the arc shrapnel (5) are close to each other but not in contact.
3. The device for lateral cerebral ventricle stabilization injection in animal experiments as claimed in claim 1, wherein an arc plate (6) is fixedly installed on the inner side of the upper end of the arc-shaped elastic sheet (5), and the upper surface of the arc plate (6) is connected with the lower end of the outer annular surface of the injector body (7).
4. The device for lateral ventricle stabilization injection of animal experiment as claimed in claim 1, wherein the middle of the upper surface of the rail frame (1) is provided with a sliding groove (13), and the sliding block (2) is matched with the sliding groove (13).
5. The device for lateral cerebral ventricle steady injection in animal experiments as claimed in claim 1, wherein the magnifying lens ring (10) is fixedly installed on the inner side of one end of the fixing plate (9) far away from the supporting rod (3), and the plate body part of the fixing plate (9) corresponding to the magnifying lens ring (10) is in an open shape.
6. A device for stable lateral animal ventriculo-ventricular injection according to claim 1, wherein the indicator needle (14) corresponds to the graduation marks (4).
7. Device for stable intracerebroventricular injection on a laboratory side of an animal according to claim 1, characterized in that said puncture needle (8) corresponds to an opening in the fixing plate (9).
8. Device for lateral ventriculo-stabilized injection in animals according to claim 1, characterized in that the end of the fixing plate (9) remote from the support bar (3) is semicircular in shape, the fixing plate (9) being made of aluminum plate.
9. A device for lateral laboratory stable injection of animals according to claim 3, characterized in that said injector body (7) is made of ferrous material, said arc plate (6) is made of magnet, said arc plate (6) is connected by means of mutual attraction between magnet and ferrous material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210479931.9A CN115317731A (en) | 2022-05-05 | 2022-05-05 | Device for stable injection of lateral ventricle of animal experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210479931.9A CN115317731A (en) | 2022-05-05 | 2022-05-05 | Device for stable injection of lateral ventricle of animal experiment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115317731A true CN115317731A (en) | 2022-11-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210479931.9A Withdrawn CN115317731A (en) | 2022-05-05 | 2022-05-05 | Device for stable injection of lateral ventricle of animal experiment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115317731A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116327416A (en) * | 2023-05-22 | 2023-06-27 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
-
2022
- 2022-05-05 CN CN202210479931.9A patent/CN115317731A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116327416A (en) * | 2023-05-22 | 2023-06-27 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
| CN116327416B (en) * | 2023-05-22 | 2023-08-25 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
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Application publication date: 20221111 |