CN115243715B - 保护以对抗血清型9、序列型16的猪链球菌的疫苗 - Google Patents

保护以对抗血清型9、序列型16的猪链球菌的疫苗

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Publication number
CN115243715B
CN115243715B CN202180020627.1A CN202180020627A CN115243715B CN 115243715 B CN115243715 B CN 115243715B CN 202180020627 A CN202180020627 A CN 202180020627A CN 115243715 B CN115243715 B CN 115243715B
Authority
CN
China
Prior art keywords
streptococcus suis
vaccine
serotype
igm protease
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202180020627.1A
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English (en)
Chinese (zh)
Other versions
CN115243715A (zh
Inventor
A·A·C·雅各布斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV filed Critical Intervet International BV
Publication of CN115243715A publication Critical patent/CN115243715A/zh
Application granted granted Critical
Publication of CN115243715B publication Critical patent/CN115243715B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN202180020627.1A 2020-03-14 2021-03-12 保护以对抗血清型9、序列型16的猪链球菌的疫苗 Active CN115243715B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20163206.4 2020-03-14
EP20163206 2020-03-14
PCT/EP2021/056285 WO2021185680A1 (en) 2020-03-14 2021-03-12 A vaccine for protection against streptococcus suis serotype 9, sequence type 16

Publications (2)

Publication Number Publication Date
CN115243715A CN115243715A (zh) 2022-10-25
CN115243715B true CN115243715B (zh) 2025-12-16

Family

ID=69844613

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180020627.1A Active CN115243715B (zh) 2020-03-14 2021-03-12 保护以对抗血清型9、序列型16的猪链球菌的疫苗

Country Status (6)

Country Link
US (1) US12383610B2 (https=)
EP (1) EP4117721A1 (https=)
JP (1) JP7728784B2 (https=)
CN (1) CN115243715B (https=)
BR (1) BR112022017316A2 (https=)
WO (1) WO2021185680A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024528172A (ja) * 2021-08-03 2024-07-26 インターベット インターナショナル ベー． フェー． 様々な血清型のストレプトコッカス・スイスに対する防御のためのワクチン
CN113832068B (zh) * 2021-10-14 2023-07-25 河南兴华生物技术有限公司 链球菌菌株及防治猪链球菌病的疫苗

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019115741A1 (en) * 2017-12-15 2019-06-20 Intervet International B.V. A vaccine for protection against streptococcus suis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201402264D0 (en) 2014-02-10 2014-03-26 Wellstream Int Ltd Composite
EP2949340A1 (en) * 2014-05-30 2015-12-02 IDT Biologika GmbH Vaccine composition against Streptococcus suis infection
US11155585B2 (en) 2015-07-09 2021-10-26 Intervacc Ab Vaccine against S. suis infection
EP3723794A1 (en) * 2017-12-15 2020-10-21 Intervet International B.V. A vaccine for protection against streptococcus suis
WO2020094762A1 (en) 2018-11-08 2020-05-14 Intervet International B.V. A vaccine for protection against streptococcus suis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019115741A1 (en) * 2017-12-15 2019-06-20 Intervet International B.V. A vaccine for protection against streptococcus suis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Streptococcus suis serotype 9 bacterin immunogenicity and protective efficacy";Nadine Büttner等;《Veterinary Immunology and Immunopathology》;20121231;第191-200页 *
"The immunoglobulin M-degrading enzyme of Streptococcus suis, IdeSsuis, is a highly protective antigen against serotype 2";Jana Seele等;《Vaccine》;20151231;第2207-2212页 *

Also Published As

Publication number Publication date
US20240197851A1 (en) 2024-06-20
US12383610B2 (en) 2025-08-12
JP7728784B2 (ja) 2025-08-25
EP4117721A1 (en) 2023-01-18
CN115243715A (zh) 2022-10-25
BR112022017316A2 (pt) 2022-10-11
JP2023517684A (ja) 2023-04-26
WO2021185680A1 (en) 2021-09-23

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