CN115119837B - Flonicamid-spirotetramat mixed preparation and application thereof - Google Patents

Flonicamid-spirotetramat mixed preparation and application thereof Download PDF

Info

Publication number
CN115119837B
CN115119837B CN202210893969.0A CN202210893969A CN115119837B CN 115119837 B CN115119837 B CN 115119837B CN 202210893969 A CN202210893969 A CN 202210893969A CN 115119837 B CN115119837 B CN 115119837B
Authority
CN
China
Prior art keywords
acid
spirotetramat
flonicamid
weight
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202210893969.0A
Other languages
Chinese (zh)
Other versions
CN115119837A (en
Inventor
吴承骏
张登科
吴克孟
毛春晖
赵显冰
鲁帝
韦高雄
程佳乐
张子翱
钟振文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YONGNONG BIOSCIENCES CO Ltd
Original Assignee
YONGNONG BIOSCIENCES CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YONGNONG BIOSCIENCES CO Ltd filed Critical YONGNONG BIOSCIENCES CO Ltd
Priority to CN202210893969.0A priority Critical patent/CN115119837B/en
Publication of CN115119837A publication Critical patent/CN115119837A/en
Application granted granted Critical
Publication of CN115119837B publication Critical patent/CN115119837B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00—Arthropodicides
    • A01P7/04—Insecticides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a flonicamid-spirotetramat mixed preparation and application thereof, which belong to the filed of pesticides, and comprise the following raw materials in parts by weight: 1-50% of flonicamid, 1-50% of spirotetramat, a stabilizer and formulation auxiliary materials; the preparation is an aqueous suspension agent; the stabilizer comprises acid and carboxylic acid dispersing agent, wherein the acid accounts for 0.1-20% of the total mass of the preparation, and the carboxylic acid dispersing agent accounts for 0.1-20% of the total mass of the preparation. According to the flonicamid-spirotetramat mixed water suspending agent, the stabilizer (acid and carboxylic acid dispersing agent are matched) is introduced, so that the reduction of the spirotetramat content of the suspending liquid after storage can be effectively inhibited.

Description

Flonicamid-spirotetramat mixed preparation and application thereof
The invention relates to a Chinese application division application with the application name of 'flonicamid and spirotetramat mixed preparation and application', wherein the application date is 2021, 08 and 10, and the application number is 202110912586.9.
Technical Field
The invention relates to the field of pesticides, in particular to a flonicamid-spirotetramat mixed preparation and application thereof.
Background
The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art.
The novel low-toxicity pyridine amide insect growth regulator pesticide developed by Nippon rock original industries, inc. has unique action mechanism, extremely high biological activity, is particularly effective on piercing-sucking mouthpart pests, has high safety and is effective on other pests with resistance to pesticides. Molecular formula C9H6F3N3O; molecular weight: 229, melting point: 157.5 ℃, vapor pressure: 2.55X10-6 Pa, solubility in water: 5.2g/L.
The spirotetramat has unique action characteristics and is one of modern pesticides with double inward suction conductivity. It can be used for preventing and treating various piercing-sucking mouthparts pests such as aphid, thrips, psyllid, mealybugs, whiteflies, scale insects, etc.
The pesticide water suspending agent (Suspension Concentrate, SC) refers to a multiphase dispersion system formed by dispersing solid raw pesticide insoluble in water with a particle size of about 0-5 microns after being processed by a certain mechanical means (sand milling or ball milling). The aqueous suspension concentrate is suitable for being processed into an original drug of an aqueous suspension concentrate, generally requires stable content in water, water solubility of less than 100mg/L and melting point of more than 60 ℃.
The dispersible oil suspending agent (oil-based suspension concentrate, OD) is a high-efficiency and environment-friendly green preparation which is pushed out by the United nations grain and agriculture organization (FAO) in recent years, and is a liquid preparation which takes environment-friendly oil as a medium and stably suspends active ingredients in the oil; common carriers of the dispersible oil suspending agent are methyl oleate, soybean oil methyl ester, 150# solvent oil and 200# solvent oil, and common emulsifying agents are calcium dodecyl benzene sulfonate, fatty alcohol polyoxyethylene ether and the like. The pesticidal active ingredients suitable for processing into dispersible oil suspensions generally have at least two characteristics: firstly, the melting point of the raw medicine is high (preferably more than 60 ℃), and secondly, the raw medicine is basically insoluble in an oil medium; otherwise, the production and processing difficulties are very high; the processing technology is grinding, namely grinding materials into particles with certain fineness by a grinding medium in a sand mill, and uniformly dispersing the particles in an oil medium by the dispersion action of a surfactant.
The soluble agent is a clear uniform liquid formed by mixing and dissolving pesticide, solvent and emulsifier, and can be infinitely mixed with water when in use.
The storage stability of the effective components of the pesticide (14 days for 54 DEG, 7 days for 0 DEG and 2 years for normal temperature storage) is a necessary condition for registering, selling and using pesticide products, and the unstable products after storage, especially pesticide products with the content decomposition rate of more than 5% after storage, cannot pass the registration permission of the pesticide inspection department in the rural area and cannot be circulated and sold on the market.
The flonicamid and spirotetramat developed and mixed water suspending agent (SC) can reduce the content of spirotetramat by 8-30% after long-time heat storage, besides the problems of particle growth and precipitation crystallization (see figure 1 and figure 2). The flonicamid and the spirotetramat are developed and mixed into a Solution (SL) and a dispersible oil suspension (OD), and the problem that the content of the spirotetramat is obviously reduced after storage is also caused.
Disclosure of Invention
Object of the Invention
The invention aims to provide a flonicamid-spirotetramat mixed preparation and application thereof, and solves the problem of reduced spirotetramat content after long-time storage.
Solution scheme
In order to achieve the aim of the invention, the embodiment of the invention provides a flonicamid-spirotetramat mixed preparation, which comprises the following raw materials in parts by weight:
1-50% of flonicamid, 1-50% of spirotetramat, a stabilizer and formulation auxiliary materials;
the preparation is an aqueous suspending agent, a soluble agent or a dispersible oil suspending agent; wherein:
when the preparation is an aqueous suspension agent, the stabilizer comprises acid and carboxylic acid dispersing agents, wherein the acid accounts for 0.1-20% of the total mass of the preparation, and the carboxylic acid dispersing agents account for 0.1-20% of the total mass of the preparation;
when the preparation is a soluble agent, the stabilizer is one or more selected from rosin, tea polyphenol, octadecyl propionate, epoxidized soybean oil, 2, 6-di-tert-butyl-p-cresol, epichlorohydrin, tert-butyl-4-hydroxyanisole, isoamyl alcohol, benzyl alcohol, phenethyl alcohol and phenoxyethanol; the stabilizer accounts for 1 to 20 percent of the total weight of the preparation;
when the preparation is a dispersible oil suspending agent, the stabilizer is one or more selected from diisooctyl succinate sodium sulfonate, 2, 6-di-tert-butyl-p-cresol, epoxidized soybean oil, triglyceryl oleate, triglyceryl linoleate, vitamin E, vitamin B3, benzyl alcohol, phenoxyethanol and hexadecanol; the stabilizer accounts for 3-60% of the total weight of the preparation.
Alternatively, when the formulation is a soluble or dispersible oil suspension, the stabilizer is benzyl alcohol and/or phenoxyethanol.
Further, when the formulation is an aqueous suspension, the aqueous suspension comprises the following ingredients in weight fraction: 1-40% of flonicamid, 1-40% of spirotetramat, 0.3-5% of acid and 1-15% of carboxylic acid dispersing agent;
optionally, the aqueous suspension comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 0.5-2% of acid and 3-8% of carboxylic acid dispersing agent.
Further, the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 0.5-2% of acid and 5% of carboxylic acid dispersing agent.
Further, the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 4-6% of carboxylic acid dispersing agent.
Further, the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of organic acid and 5% of carboxylic acid dispersing agent.
Further, the acid is one or more of dodecylbenzene sulfonic acid, dilute hydrochloric acid, dilute sulfuric acid, phosphoric acid, lactic acid, taurine, succinic acid, glycyrrhizic acid, methylsulfonic acid, chloroacetic acid, glacial acetic acid, benzoic acid, salicylic acid, citric acid, malic acid, tartaric acid and ascorbic acid;
optionally, the acid is selected from one or more of dilute hydrochloric acid, phosphoric acid, lactic acid, methanesulfonic acid and citric acid.
Optionally, the carboxylic acid dispersant is methacrylic acid-methacrylate-polyethylene glycol terpolymer and ATLOX TM 4913 One or more of (CRODA), agrilan 755 (Nouryon), tersperse 2500 (Indoroma), and EMULSON AG/TRN 14105; optionally, the carboxylic acid dispersant is methacrylic acid-methacrylate-polyethylene glycol terpolymer.
Further, the water suspending agent comprises the following raw materials in parts by weight: 15-20% of flonicamid, 10-20% of spirotetramat, 1-2% of acid and 5% of carboxylic acid dispersing agent, wherein the acid is selected from one of phosphoric acid, dilute lactic acid hydrochloride and methylsulfonic acid, and the carboxylic acid dispersing agent is methacrylic acid-methacrylate-polyethylene glycol terpolymer.
Further, the preparation also contains the following auxiliary materials in parts by weight: 0.1 to 1 percent of xanthan gum, 0.5 to 2 percent of magnesium aluminum silicate, 0.01 to 0.5 percent of isothiazolinone, 2 to 8 percent of glycol and 0.1 to 0.5 percent of defoamer.
Further, the preparation also contains the following auxiliary materials in parts by weight: 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol and 0.2% of defoamer; optionally, the defoamer is simethicone polyether.
Preferably: the water suspending agent comprises the following raw materials in parts by weight: 15-20% of flonicamid, 10-20% of spirotetramat, 1-2% of acid, 5% of carboxylic acid dispersing agent, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol and 0.2% of simethicone polyether; optionally, the acid is selected from one of phosphoric acid, dilute hydrochloric acid, lactic acid and methanesulfonic acid, preferably, the acid is an organic acid, the organic acid can be lactic acid or methanesulfonic acid, and the carboxylic acid dispersant is methacrylic acid-methacrylate-polyethylene glycol terpolymer.
Further, when the formulation is a soluble formulation, the soluble formulation comprises the following raw materials in weight fraction: 1-40% of flonicamid, 1-40% of spirotetramat, 1-20% of stabilizer and 10-80% of solvent;
optionally, the soluble agent comprises the following raw materials in parts by weight: 10-20% of flonicamid, 8-20% of spirotetramat, 1-20% of stabilizer and 10-80% of solvent.
Further, the solvent is selected from one or more of propylene glycol methyl ether, propylene glycol ethyl ether, N-methylpyrrolidone, N-ethylpyrrolidone, N-butylpyrrolidone, N-octylpyrrolidone, N-dimethylformamide, N-dimethylacetamide, N-dimethyldecanoamide, gamma-butyrolactone and 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate; optionally, the solvent is selected from one or more of propylene glycol diethyl ether, N-methylpyrrolidone, N-ethylpyrrolidone, N-butylpyrrolidone, N-octylpyrrolidone, N-dimethylformamide, N-dimethylacetamide and N, N-dimethyldecanoamide; optionally, the solvent is selected from one or more of propylene glycol diethyl ether, N-methyl pyrrolidone, N-ethyl pyrrolidone, N-octyl pyrrolidone and N, N-dimethyl decyl amide.
Optionally, the soluble agent comprises the following raw materials in parts by weight: 12-15% of flonicamid, 8-12% of spirotetramat, 10-15% of stabilizer and 20-30% of solvent; optionally, the soluble agent comprises the following raw materials in parts by weight: 12-15% of flonicamid, 8-12% of spirotetramat, 15% of stabilizer and 20% of solvent; optionally, the solvent is selected from one or more of propylene glycol diethyl ether, N-octyl pyrrolidone and N, N-dimethyl decyl amide; optionally, the stabilizer is one or more of benzyl alcohol, phenethyl alcohol and phenoxyethanol.
Further, the preparation also comprises the following emulsifying agent and filling medium in parts by weight: 1-8% of propylene glycol block polyether, 3-8% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate; optionally propylene glycol block polyether 3%, fatty alcohol polyoxyethylene ether 5%, propylene glycol methyl ether acetate 100%;
optionally, the preparation further comprises the following emulsifying agent and filling medium in parts by weight: 1-8% of butanol block polyether, 3-8% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate; optionally 5% of butanol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Preferably, the soluble agent comprises the following raw materials in parts by weight: 12-15% of flonicamid, 8-12% of spirotetramat, 15% of stabilizer, 20% of solvent, 3% of propylene glycol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate; optionally, the solvent is selected from one or more of propylene glycol diethyl ether, N-octyl pyrrolidone and N, N-dimethyl decyl amide; optionally, the stabilizer is one or more of benzyl alcohol, phenethyl alcohol and phenoxyethanol.
Preferably, the soluble agent comprises the following raw materials in parts by weight: 12-15% of flonicamid, 8-12% of spirotetramat, 15% of stabilizer, 20% of solvent, 5% of butanol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate; optionally, the solvent is selected from one or more of propylene glycol diethyl ether, N-octyl pyrrolidone and N, N-dimethyl decyl amide; optionally, the stabilizer is one or more of benzyl alcohol, phenethyl alcohol and phenoxyethanol.
Further, when the formulation is a dispersible oil suspension agent, the dispersible oil suspension agent comprises the following raw materials in parts by weight: 1-30% of flonicamid, 1-30% of spirotetramat, 3-60% of stabilizer, 10-30% of emulsifier and 10-60% of medium oil;
optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 3-40% of stabilizer, 10-30% of emulsifier and 10-59% of medium oil (medium oil is preferably 19-59%);
optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 3-40% of stabilizer, 16-23% of emulsifier and 10-51% of medium oil (medium oil is preferably 19-51%);
optionally, the stabilizer is one or more selected from sodium diisooctyl succinate, 2, 6-di-tert-butyl-p-cresol, epoxidized soybean oil, triglyceryl oleate, triglyceryl linoleate, benzyl alcohol, phenoxyethanol and hexadecanol.
Optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 20-40% of stabilizer, 23% of emulsifier and 10-31% of medium oil (medium oil is preferably 19-31%); optionally, the stabilizer is one or more of oleic acid triglyceride, linoleic acid triglyceride, cetyl alcohol, benzyl alcohol and epoxidized soybean oil.
Optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 20% of stabilizer, 23% of emulsifier and 19-31% of medium oil; optionally, the stabilizer is one or more of oleic acid triglyceride, linoleic acid triglyceride, cetyl alcohol, benzyl alcohol and epoxidized soybean oil; further optionally, the stabilizer is benzyl alcohol and/or epoxidized soybean oil; further alternatively, when the stabilizer is a triglyceride linoleate, the medium oil comprises methyl linolenate, the methyl linolenate comprising at least 20% of the formulation.
Optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 40% of stabilizer, 23% of emulsifier and 10-19% of medium oil; optionally, the stabilizer is a triglyceride of linoleic acid.
Optionally, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 3-7% of stabilizer, 23% of emulsifier and 36-54% of medium oil; the stabilizer is selected from diisooctyl sodium sulfosuccinate and/or 2, 6-di-tert-butyl-p-cresol.
Alternatively, the medium oil is a medium oil in a common sense, including methyl oleate, methyl linoleate, methyl stearate, solvent oil, pine ester oil, mineral oil and the like which are common carrier medium oils in the industry; optionally, the medium oil is selected from one or two of methyl oleate, methyl linoleate, methyl stearate, corn oil and soybean oil;
optionally, the emulsifier is one or more selected from calcium dodecyl benzene sulfonate, castor oil polyoxyethylene ether, tristyrylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, polyoxyethylene ether oleoyl ricinoleate and sorbitan monooleate polyoxyethylene ether. Wherein, the fatty alcohol polyoxyethylene ether, polyoxyethylene ether oleoyl ricinoleate and sorbitan monooleate polyoxyethylene ether belong to vegetable oil emulsifier.
Optionally, the preparation also contains the following auxiliary materials in parts by weight: 1% of organic bentonite and 1% of gas-phase white carbon black.
Preferably, the dispersible oil suspending agent comprises the following raw materials in parts by weight: 10-16% of flonicamid, 8-16% of spirotetramat, 20-40% of stabilizer, 23% of emulsifier and 19-31% of medium oil, and optionally, one or more of linoleic acid triglyceride, benzyl alcohol and epoxidized soybean oil. The emulsifier is at least two selected from calcium dodecyl benzene sulfonate, polyoxyethylene ether oleoyl ricinoleate, fatty alcohol polyoxyethylene ether and polyoxyethylene ether oleoyl ricinoleate.
The emulsifier comprises the following raw materials in total weight of the preparation: 8% of calcium dodecyl benzene sulfonate, 5% of polyoxyethylene ether oleoyl ricinoleate and 8% of fatty alcohol polyoxyethylene ether.
Alternatively, the emulsifier comprises the following materials in total weight of the formulation: 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether and 5% of castor oil polyoxyethylene ether.
Alternatively, the emulsifier comprises the following materials in total weight of the formulation: 8-8% of calcium dodecyl benzene sulfonate and 15% of polyoxyethylene ether oleoyl ricinoleate.
Further, the water suspending agent, the soluble agent or the dispersible oil suspending agent preparation also contains a coloring agent; such as azo dyes or triphenylmethane dyes.
On the other hand, the preparation method of the flonicamid-spirotetramat mixed preparation is characterized in that,
when the preparation is an aqueous suspension, the preparation method comprises the following steps: firstly, mixing the flonicamid raw material, the spirotetramat raw material, the auxiliary material and water in proportion, shearing and sanding until the particle size is smaller than 5 microns to obtain a suspending agent with uniform appearance and dispersibility in water;
when the preparation is a soluble agent, the preparation method comprises the following steps: firstly, mixing the flonicamid raw material, the spirotetramat raw material, the auxiliary material and the solvent in proportion, heating and stirring for 10-20 minutes at 30-40 ℃ until the mixture is clear and transparent;
when the preparation is a dispersible oil suspending agent, the preparation method comprises the following steps: the preparation method comprises the steps of mixing the flonicamid raw material, the spirotetramat raw material, the emulsifying agent and the auxiliary materials in proportion, and grinding the mixture by a sand mill to obtain the dispersible oil suspending agent.
In still another aspect, the application of the flonicamid-spirotetramat mixed preparation in controlling plant insect pests is provided.
Further, the plant diseases and insect pests are piercing-sucking mouthparts pests.
The equipment of the processing technology of the preparation of the invention is publicly known.
Advantageous effects
According to the flonicamid-spirotetramat mixed water suspending agent, the stabilizer (acid and carboxylic acid dispersing agent are matched) is introduced, so that the reduction of the spirotetramat content of the suspending liquid after storage can be effectively inhibited. The flonicamid and spirotetramat are mixed into a soluble solution, and a stabilizer is introduced to further screen a solvent, so that the content reduction of spirotetramat can be effectively inhibited. The flonicamid and spirotetramat are mixed with the dispersible oil suspending agent, and the corresponding emulsifying agent is screened by screening the stabilizer and the medium oil type, so that the content reduction of spirotetramat can be effectively inhibited.
Drawings
One or more embodiments are illustrated by way of example and not limitation in the figures of the accompanying drawings. The word "exemplary" is used herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.
FIG. 1 is a content chromatogram of spirotetramat after 14 days of storage at normal temperature in the prior art;
FIG. 2 is a chromatogram of the content of the spirotetramat after 14 days of heat storage at 54 ℃.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention. Throughout the specification and claims, unless explicitly stated otherwise, the term "comprise" or variations thereof such as "comprises" or "comprising", etc. will be understood to include the stated element or component without excluding other elements or components.
In addition, numerous specific details are set forth in the following description in order to provide a better illustration of the invention. It will be understood by those skilled in the art that the present invention may be practiced without some of these specific details. In some embodiments, materials, elements, methods, means, etc. well known to those skilled in the art are not described in detail in order to highlight the gist of the present invention. The percentages in all the formulas of the invention are weight ratios.
The flonicamid and spirotetramat of the invention can be obtained in a commercial mode.
1. Preparation of a Water-dispersible suspension agent:
preparation of a Water-dispersible suspension agent: firstly, the flonicamid, the spirotetramat raw medicine, the auxiliary agent and water are weighed and mixed, sheared for a certain time, and sanded until the particle size is smaller than 5 microns, so as to obtain the suspending agent which has uniform appearance and can be dispersed in water. Specific formulation examples are as follows:
example 1 (no stabilizer):
15% of flonicamid, 10% of spirotetramat, 5% of tritolyl polyether phosphate triethanolamine salt, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoamer and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 2:
15% of flonicamid, 10% of spirotetramat, 0.5% of methylsulfonic acid, 5% of trisstyrol polyether phosphate triethanolammonium salt, 2% of EO-PO block polyether dispersant, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of glycol, 0.2% of defoamer and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 3:
15% of flonicamid, 10% of spirotetramat, 1.5% of methylsulfonic acid, 5% of trisstyrol polyether phosphate triethanolammonium salt, 2% of EO-PO block polyether dispersant, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of glycol, 0.2% of defoamer and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 4:
15% of flonicamid, 10% of spirotetramat, 1.5% of methylsulfonic acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoamer and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 5:
15% of flonicamid, 10% of spirotetramat, 2% of phosphoric acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 6:
10% of flonicamid, 8% of spirotetramat, 2% of dilute hydrochloric acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension agent.
Example 7:
18% of flonicamid, 12% of spirotetramat, 1.5% of lactic acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension.
Example 8:
8% of flonicamid, 15% of spirotetramat, 1% of citric acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension agent.
Example 9:
20% of flonicamid, 20% of spirotetramat, 1% of methylsulfonic acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension agent.
Example 10:
20% of flonicamid, 20% of spirotetramat, 2% of methylsulfonic acid, 5% of methacrylic acid-methacrylate-polyethylene glycol terpolymer, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol, 0.2% of defoaming agent and the balance of water, and grinding the materials by a sand mill to prepare the water suspension agent.
The defoamer of the above embodiment is simethicone polyether.
The contents of flonicamid and spirotetramat after 14 days of storage at 54℃in each of the above examples of the aqueous suspension are shown in the following table. In table 1, example 2..the term "example 10" refers to example 1, example 2..the term "example 10".
TABLE 1 Water suspending agent content and decomposition Rate after heat storage
As can be seen from Table 1, the dissolution rate of spirotetramat is as high as 32% after 14 days of heat storage at 54 ℃ without using the stabilizer of the invention in example 1; in the examples 2 and 3, the organic acid stabilizer provided by the invention is only used, and after 14 days of heat storage at 54 ℃, the decomposition rate of the spirotetramat is respectively 21% and 14%, and compared with the example 1, the decomposition rate is obviously improved, but the decomposition rate is still higher; the combination scheme of the invention is adopted in examples 4-10, and the decomposition rate of spirotetramat after 14 days of heat storage at 54 ℃ can be controlled below 5%, which accords with the content quality standard requirement of the pesticide preparation product after heat storage.
2. Preparation of the soluble agent:
preparation of the soluble agent: firstly, the flonicamid and the spirotetramat are used as raw materials, the auxiliary agent and the solvent are weighed and mixed, and then the mixture is heated and stirred for 10 to 20 minutes at the temperature of between 30 and 40 ℃ until the mixture is clear and transparent. Specific formulation examples are as follows:
example 1:
15% of flonicamid, 10% of spirotetramat, 20% of N-octyl pyrrolidone, 3% of propylene glycol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 2:
15% of flonicamid, 10% of spirotetramat, 30% of N-octyl pyrrolidone, 3% of propylene glycol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 3:
15% of flonicamid, 10% of spirotetramat, 20% of N-octyl pyrrolidone, 10% of benzyl alcohol, 3% of propylene glycol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 4:
15% of flonicamid, 10% of spirotetramat, 20% of N-octyl pyrrolidone, 15% of benzyl alcohol, 3% of propylene glycol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 5:
15% of flonicamid, 10% of spirotetramat, 20% of N, N-dimethyl capramide, 15% of phenoxyethanol, 5% of butanol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 6:
14% of flonicamid, 12% of spirotetramat, 20% of N-octyl pyrrolidone, 15% of phenethyl alcohol, 5% of butanol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
Example 7:
12% of flonicamid, 8% of spirotetramat, 20% of propylene glycol diethyl ether, 15% of phenethyl alcohol, 5% of butanol block polyether, 5% of fatty alcohol polyoxyethylene ether and 100% of propylene glycol methyl ether acetate.
After 14 days of storage of the samples of the above examples at 54℃the flonicamid and spirotetramat contents are as shown in the following table. In table 2, example 1, example 2..example 7 refers to example 1, example 2..example 7.
TABLE 2 Table of the contents and decomposition rates of the solutions after heat storage
From Table 2, examples 1 to 2, in which the stabilizer of the present invention was not used, showed that the decomposition rate of spirotetramat was as high as 12 to 18% after 14 days of heat storage at 54℃and the solvent did not exert an obvious stabilizing effect; examples 3-7 use the stabilizer scheme of the invention, the decomposition rate of spirotetramat is obviously reduced after 14 days of heat storage at 54 ℃, and except example 3, the decomposition rate can be controlled below 5%, and the requirements of the quality standard of the content of the heat storage pesticide preparation products are met.
3. Dispersible oil suspension agent
Preparation of dispersible oil suspending agent: the flonicamid, spirotetramat technical, emulsifying agent, dispersing agent, thickening agent, methyl ester oil and the like are weighed and mixed, and then the mixture is ground by a sand mill to prepare the dispersible oil suspending agent. Specific formulation examples are as follows:
example 1:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 2:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 1% of organic bentonite, 1% of gas-phase white carbon black, 20% of methyl palmitate and 100% of methyl oleate.
Example 3:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 1% of organic bentonite, 1% of gas-phase white carbon black, 20% of methyl stearate and 100% of methyl oleate.
Example 4:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 1% of organic bentonite, 1% of gas-phase white carbon black, 20% of methyl linolenate and 100% of methyl oleate.
Example 5:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 20% of linoleic acid triglyceride, 1% of organic bentonite, 1% of gas-phase white carbon black, 20% of linolenic acid methyl ester and 100% of oleic acid methyl ester.
Example 6:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of polyoxyethylene ether oleoyl ricinoleate, 20% of linoleic acid triglyceride, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of oleic acid methyl ester.
Example 7:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 5% of polyoxyethylene ether oleoyl ricinoleate, 8% of fatty alcohol polyoxyethylene ether, 20% of oleic acid triglyceride, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 8:
10% of flonicamid, 8% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 5% of polyoxyethylene ether oleoyl ricinoleate, 8% of fatty alcohol polyoxyethylene ether, 40% of linoleic acid triglyceride, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of methyl oleate.
Example 9:
16% of flonicamid, 10% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of castor oil polyoxyethylene ether, 20% of benzyl alcohol, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 10:
16% of flonicamid, 10% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 20% of cetyl alcohol, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 11:
16% of flonicamid, 10% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of diisooctyl succinate sodium sulfonate, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 12:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 7% of sodium diisooctyl succinate, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 13:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 3% of 2, 6-di-tert-butyl-p-cresol, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of methyl oleate.
Example 14:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 5% of 2, 6-di-tert-butyl-p-cresol, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of methyl oleate.
Example 15:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 8% of fatty alcohol polyoxyethylene ether, 20% of epoxidized soybean oil, 1% of organic bentonite, 1% of gas-phase white carbon black and 100% of methyl oleate.
Example 16:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 15% of polyoxyethylene ether oleoyl ricinoleate, 20% of epoxidized soybean oil, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of soybean oil.
Example 17:
16% of flonicamid, 16% of spirotetramat, 8% of calcium dodecyl benzene sulfonate, 15% of polyoxyethylene ether oleoyl ricinoleate, 20% of epoxidized soybean oil, 1% of organic bentonite, 1% of gas phase white carbon black and 100% of corn oil.
After 14 days of storage of the samples of the above examples at 54℃the flonicamid and spirotetramat contents are as shown in the following table. In table 3, example 1, example 2..example 17 refers to example 1, example 2..example 17.
TABLE 3 Table 3 content and decomposition Rate of dispersible oil suspending agent after heat storage
/>
As can be seen from Table 3, in example 1, the decomposition rate of spirotetramat was as high as 18% after heat-storing at 54℃for 14 days without using the stabilizer of the present invention, while in examples 2 to 4, the decomposition rate of spirotetramat was varied to a different extent after heat-storing at 54℃for 14 days while increasing or changing the kind of medium oil, but still a relatively high decomposition rate was present; except for example 6 and example 12 (the content of the spirotetramat is obviously improved in comparison with example 1), the decomposition rate of spirotetramat can be controlled below 5% after the spirotetramat is thermally stored for 14 days at 54 ℃ by using the stabilizer scheme of the invention in examples 5-17, and the requirements of the quality standard of the content of the pesticide preparation products after the heat storage are met. The inventors of the present invention have also found an interesting phenomenon: the stabilizers used in examples 5, 6 and 8 are all linoleic acid triglyceride, but the decomposition rate of example 6 is obviously higher than that of examples 8 and 5, and the medium oil methyl linolenate in example 5 probably plays a certain role in stabilizing, but the decomposition rate of spirotetramat can be obviously reduced when methyl linolenate is replaced by linoleic acid triglyceride (namely example 8).
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (23)

1. The flonicamid-spirotetramat mixed preparation is characterized by comprising the following raw materials in parts by weight:
the preparation is an aqueous suspending agent, and the aqueous suspending agent comprises the following raw materials in parts by weight: 1-40% of flonicamid, 1-40% of spirotetramat, 0.3-5% of acid, 1-15% of carboxylic acid dispersing agent and formulation auxiliary materials;
the carboxylic acid dispersing agent is methacrylic acid-methacrylate-polyethylene glycol terpolymer and ATLOX TM 4913. One or more of Agrilan 755, tersperse 2500 and EMULSON AG/TRN 14105;
the acid is one or more of dodecylbenzene sulfonic acid, dilute hydrochloric acid, dilute sulfuric acid, phosphoric acid, lactic acid, taurine, succinic acid, glycyrrhizic acid, methanesulfonic acid, chloroacetic acid, glacial acetic acid, benzoic acid, salicylic acid, citric acid, malic acid, tartaric acid and ascorbic acid.
2. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 0.5-2% of acid and 3-8% of carboxylic acid dispersing agent.
3. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 3-8% of carboxylic acid dispersing agent.
4. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 5-8% of carboxylic acid dispersing agent.
5. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 0.5-2% of acid and 5% of carboxylic acid dispersing agent.
6. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 4-6% of carboxylic acid dispersing agent.
7. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 5-6% of carboxylic acid dispersing agent.
8. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 8-20% of flonicamid, 8-20% of spirotetramat, 1-2% of acid and 5% of carboxylic acid dispersing agent.
9. The flonicamid-spirotetramat mixed formulation of claim 1, wherein the water suspending agent comprises the following raw materials in parts by weight: 15-20% of flonicamid, 10-20% of spirotetramat, 1-2% of acid and 5% of carboxylic acid dispersing agent.
10. The flonicamid-spirotetramat formulation of claim 1, wherein the carboxylic acid dispersant is a methacrylic acid-methacrylate-polyethylene glycol terpolymer.
11. The flonicamid-spirotetramat mixed formulation according to any one of claims 1 to 10, wherein the acid is one or more selected from the group consisting of dilute hydrochloric acid, phosphoric acid, lactic acid, methylsulfonic acid and citric acid.
12. The flonicamid-spirotetramat mixed formulation according to any one of claims 1 to 10, further comprising the following auxiliary materials in parts by weight: 0.1 to 1 percent of xanthan gum, 0.5 to 2 percent of magnesium aluminum silicate, 0.01 to 0.5 percent of isothiazolinone, 2 to 8 percent of glycol and 0.1 to 0.5 percent of defoamer.
13. The flonicamid-spirotetramat formulation of claim 12, wherein the defoamer is simethicone polyether.
14. The flonicamid-spirotetramat mixed formulation according to any one of claims 1 to 10, further comprising the following auxiliary materials in parts by weight: xanthan gum 0.2%, magnesium aluminum silicate 1%, isothiazolinone 0.1%, ethylene glycol 4% and simethicone polyether 0.2%.
15. The flonicamid-spirotetramat mixed formulation according to any one of claims 1 to 10, wherein the aqueous suspension comprises the following raw materials in parts by weight: 15-20% of flonicamid, 10-20% of spirotetramat, 1-2% of acid, 5% of carboxylic acid dispersing agent, 0.2% of xanthan gum, 1% of magnesium aluminum silicate, 0.1% of isothiazolinone, 4% of ethylene glycol and 0.2% of simethicone polyether.
16. The flonicamid-spirotetramat formulation of claim 15, wherein the acid is selected from one of phosphoric acid, dilute hydrochloric acid, lactic acid and methylsulfonic acid.
17. The flonicamid-spirotetramat formulation of claim 15, wherein the acid is an organic acid.
18. The flonicamid-spirotetramat formulation of claim 17, wherein the organic acid is lactic acid or methylsulfonic acid and the carboxylic acid dispersant is methacrylic acid-methacrylate-polyethylene glycol terpolymer.
19. The flonicamid-spirotetramat mixed formulation according to any one of claims 1 to 10, further comprising a coloring agent.
20. The flonicamid-spirotetramat formulation of claim 19, wherein the coloring agent is an azo dye or a triphenylmethane dye.
21. A process for preparing the flonicamid-spirotetramat compound formulation of any one of claims 1 to 20, characterized in that:
when the preparation is an aqueous suspension, the preparation method comprises the following steps: the flonicamid raw material, the spirotetramat raw material, the auxiliary material and water are mixed according to a proportion, sheared and sanded until the particle size is smaller than 5 microns, and the suspending agent with uniform appearance and dispersibility in water is obtained.
22. Use of the flonicamid-spirotetramat compound formulation of any one of claims 1 to 20 or the flonicamid-spirotetramat compound formulation prepared by the preparation method of claim 21 for controlling plant pests.
23. The use of claim 22, wherein the plant pest is a piercing-sucking mouth gag pest.
CN202210893969.0A 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof Active CN115119837B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210893969.0A CN115119837B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202210893969.0A CN115119837B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof
CN202110912586.9A CN113508819B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN202110912586.9A Division CN113508819B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof

Publications (2)

Publication Number Publication Date
CN115119837A CN115119837A (en) 2022-09-30
CN115119837B true CN115119837B (en) 2023-12-26

Family

ID=78068935

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202210893969.0A Active CN115119837B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof
CN202110912586.9A Active CN113508819B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202110912586.9A Active CN113508819B (en) 2021-08-10 2021-08-10 Flonicamid-spirotetramat mixed preparation and application thereof

Country Status (1)

Country Link
CN (2) CN115119837B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115956567A (en) * 2022-10-10 2023-04-14 上海生农生化制品股份有限公司 Flonicamid-spirotetramat insecticidal composition and application thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578121A (en) * 2011-12-19 2012-07-18 河南金田地农化有限责任公司 Pesticide insecticidal and acaricidal composition containing spiroteramat
CN102696582A (en) * 2012-04-23 2012-10-03 广东中迅农科股份有限公司 Flonicamid suspension concentrate and method for preparing same
CN103858899A (en) * 2012-12-12 2014-06-18 王丽君 Pesticide composition containing spirotetramat and amide insecticide
CN106417330A (en) * 2016-09-19 2017-02-22 佛山市盈辉作物科学有限公司 Insecticidal composition containing cyclaniliprole and spirotetramat
CN109452267A (en) * 2018-11-22 2019-03-12 深圳诺普信农化股份有限公司 The preparation method and aqueous pesticide formulations of aqueous pesticide formulations
CN111328819A (en) * 2020-04-20 2020-06-26 六夫丁作物保护有限公司 Low-temperature-resistant suspending agent containing spirotetramat and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103609585B (en) * 2012-05-24 2015-03-04 永农生物科学有限公司 Composite pesticide composition containing spirodiclofen and clothianidin and preparation thereof
CN106489964A (en) * 2016-10-21 2017-03-15 青岛瀚生生物科技股份有限公司 Spiral shell worm ethyl ester containing mineral oil dispersibles oil-suspending agent and preparation method thereof, application

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578121A (en) * 2011-12-19 2012-07-18 河南金田地农化有限责任公司 Pesticide insecticidal and acaricidal composition containing spiroteramat
CN102696582A (en) * 2012-04-23 2012-10-03 广东中迅农科股份有限公司 Flonicamid suspension concentrate and method for preparing same
CN103858899A (en) * 2012-12-12 2014-06-18 王丽君 Pesticide composition containing spirotetramat and amide insecticide
CN106417330A (en) * 2016-09-19 2017-02-22 佛山市盈辉作物科学有限公司 Insecticidal composition containing cyclaniliprole and spirotetramat
CN109452267A (en) * 2018-11-22 2019-03-12 深圳诺普信农化股份有限公司 The preparation method and aqueous pesticide formulations of aqueous pesticide formulations
CN111328819A (en) * 2020-04-20 2020-06-26 六夫丁作物保护有限公司 Low-temperature-resistant suspending agent containing spirotetramat and preparation method thereof

Also Published As

Publication number Publication date
CN113508819A (en) 2021-10-19
CN113508819B (en) 2022-09-02
CN115119837A (en) 2022-09-30

Similar Documents

Publication Publication Date Title
EP1742533B1 (en) Use of alkykl carboxylic acid amides as penetration promoters
JP7205835B2 (en) Fat-soluble nutrient microcapsules and method for producing the same
EP1916998B1 (en) Sterol ester powder
US11278856B2 (en) Lutein microcapsule formulation and preparation method thereof
CN115119837B (en) Flonicamid-spirotetramat mixed preparation and application thereof
CN103858861B (en) A kind of environmentally friendly emamectin-benzoate aqua and preparation method thereof
CN103858936A (en) Multifunctional environment-friendly emamectin benzoate aqueous solution and preparation method thereof
CN104872115A (en) Dispersible oil suspending agent additive for soybean oil system and dispersible oil suspending agent
CN108208763B (en) Acid-stable emulsion composition and preparation method thereof
CN101129331A (en) Method of preparing transparent water dispersion type lycopene concentrated liquor
EP1916912B1 (en) Powdery sterol formulations comprising colloid-forming agents
CN102224934A (en) Preparation method of vitamin A microcapsule nutrition enhancer for beverage
WO2005046361A1 (en) Protein powder and protein-containing drink obtained therefrom
EP2099320A1 (en) Method for producing sterol formulations
CN108552168A (en) A kind of high stability imidacloprid liquor
CN103907643A (en) Multifunctional environment-friendly acetamiprid aqua and preparation method thereof
CN113615687B (en) Pyraclostrobin nano microcapsule and preparation method and application thereof
CN110934253B (en) Preparation method of nano transparent water dispersed curcumin
CN107494528B (en) Epoxiconazole suspension concentrate and preparation method thereof
WO2008138155A2 (en) Emulsion preconcentrates and micellar formulations containing wood resins
CN110150283A (en) A kind of Envidor suspending agent and preparation method thereof
CN108112702A (en) A kind of baby formula milk powder and preparation method thereof
EP3487319A1 (en) Propyl gallate-containing vitamin preparations
EP2838375B1 (en) Production of biomass hetero-colloidal systems
CN117136971B (en) Wheat growth regulator and preparation method and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant