CN115105445A - PEG-emulsifier-free skin moistening cream composition for infants and children and preparation method thereof - Google Patents

Abstract

The invention discloses a PEG emulsifier-free baby skin cream composition and a preparation method thereof, belonging to the technical field of cosmetics, wherein the PEG emulsifier-free baby skin cream composition comprises an emulsifier, a thickening stabilizer, a emollient, a moisturizer, a humectant, a co-emulsifier, a skin conditioner, an antioxidant and a pH regulator; the emulsifier comprises polyglyceryl-3-methylglucose distearate, polyglyceryl-3 distearate, glyceryl stearate citrate; the skin care cream disclosed by the invention abandons the traditional PEG emulsifier, forms a stable oil-in-water cream by using a plant-derived degradable polyglycerol emulsifier, is mild and non-irritant, effectively strengthens and consolidates the skin barrier by adopting the matching of a natural emollient and active substances such as the echium japonicum seed oil and the sunflower seed oil unsaponifiable substance, and reduces the reaction of the skin to external stimulation by adding the ardisia japonica extract and rhamnose, so that the effects of preventing the skin of infants and children from being excessively sensitive and providing instant relief for the skin are achieved.

Description

PEG-emulsifier-free skin moistening cream composition for infants and children and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a skin-moistening cream composition for infants without a PEG emulsifier and a preparation method thereof.

Background

The infant product is one of the fastest growing products in the daily chemical industry, and in view of the characteristics of thin skin epidermal layer, small keratinocyte, low sebum content, high percutaneous water loss rate and the like of the infant, the barrier function and the immune system of the infant are imperfect, the defense capability is poor, and the infant product is easy to be attacked by external stimuli, so that the positioning of the infant product is mainly safe and mild, the matching of the emulsifying agent is particularly important when the formula of the cream is designed for the infant, and the stability of the cream is effectively ensured by using the conventional PEG emulsifying agent, but the safety and the naturalness of the product are slightly deficient for the sensitive skin of the infant.

Disclosure of Invention

The invention aims to provide a skin-moistening cream composition for infants without a PEG emulsifier and a preparation method thereof, so as to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a skin caring cream composition for infants without PEG emulsifier comprises emulsifier, thickening stabilizer, emollient, thickener, humectant, auxiliary emulsifier, skin conditioner, antioxidant, pH regulator, aromatic, and solvent;

the emulsifier comprises polyglyceryl-3-methylglucdistearate, polyglyceryl-3-distearate, glyceryl stearate citrate.

As a further scheme of the invention: the skin conditioning agent comprises allantoin, octyldodecanol, echium oil, sunflower oil unsaponifiable matter, extract of fructus seu radix camptothecae acuminatae, tocopherol, and rhamnose.

As a further scheme of the invention: the emollient comprises palmitic acid and stearic acid.

As a further scheme of the invention: the emollient comprises shea butter, glyceryl tri (ethyl hexanoate), isopropyl myristate, phytosterol isostearate, coco-caprylate/caprate, dimethicone.

As a further scheme of the invention: the humectant comprises butanediol, glycerol, sodium hyaluronate and 1, 2-hexanediol.

As a further scheme of the invention: the thickening stabilizing agent is cetostearyl alcohol, the thickening agent is carbomer, the co-emulsifier is hydrogenated lecithin, the antioxidant is p-hydroxyacetophenone, the pH regulator is tromethamine, and the solvent is water.

As a further scheme of the invention: the composition is prepared from the following components in percentage by weight: 2.5 to 3.8 percent of polyglycerol-3-methyl glucose distearate, 0.89 to 1.14 percent of polyglycerol-3 distearate, 0.04 to 0.06 percent of glycerol stearate citrate, 1.0 to 1.5 percent of thickening stabilizer, 0.4 to 0.6 percent of palmitic acid, 0.3 to 0.4 percent of stearic acid, 0.8 to 2 percent of shea butter, 3.8 to 5 percent of glycerol tri (ethyl hexanoate), 2.3 to 4 percent of isopropyl myristate, 0.35 to 0.5 percent of phytosterol isostearate, 1.8 to 3 percent of coco-caprylate/caprate, 2.9 to 3 percent of polydimethylsiloxane, 0.11 to 0.25 percent of thickening agent, 4.3 to 5 percent of butanediol, 5 to 9 percent of glycerol, 0.06 to 0.07 percent of sodium hyaluronate, and 0.48 to 0.5 percent of 1, 2-hexanediol, 0.2 to 0.3 percent of co-emulsifier, 0.01 to 0.2 percent of allantoin, 0.05 to 0.9385 percent of octyldodecanol, 0.04 to 0.05 percent of cynara scolymus seed oil, 0.01 to 0.05 percent of sunflower seed oil unsaponifiable matter, 0.001 percent of ardisia japonica extract, 0.0005 percent of tocopherol, 0.01 to 0.9 percent of rhamnose, 0.2 to 0.5 percent of antioxidant, 0.01 to 0.18 percent of pH regulator, 0.01 to 0.15 percent of aromatic agent and the balance of solvent.

As a further scheme of the invention: the composition is prepared from the following components in percentage by weight: polyglycerol-3-methylglucdistearate 2.5%, polyglycerol-3-distearate 1.14%, glycerol stearate citrate 0.06%, thickening stabiliser 1.5%, palmitic acid 0.6%, stearic acid 0.4%, shea butter 2%, glycerol tri (ethylhexanoate) 5%, isopropyl myristate 4%, phytosterol isostearate 0.5%, coco-caprylate/caprate 3%, polydimethylsiloxane 3%, thickener 0.25%, butylene glycol 5%, glycerol 5%, sodium hyaluronate 0.06%, 1, 2-hexanediol 0.5%, co-emulsifier 0.3%, allantoin 0.2%, octyldodecanol 0.9385%, echium oil 0.05%, sunflower seed oil unsaponifiable 0.01%, illicium extract 0.001%, tocopherol 0.0005%, rhamnose 0.9%, antioxidant 0.5%, pH adjuster 0.18%, fragrance 0.15%, and, The solvent is the rest.

The preparation method of the PEG-free skin-moistening cream composition for infants comprises the following steps:

s1, adding the emulsifier, the thickening stabilizer, the emollient and the emollient into an oil pan, stirring and heating to 80-85 ℃ until the emulsifier, the thickening stabilizer, the emollient and the emollient are completely dissolved and no particles exist for later use;

s2, adding a thickening agent, a solvent accounting for 10% of the total amount of the solvent, butanediol accounting for 15% of the total amount of the butanediol, an auxiliary emulsifier, glycerol, allantoin and sodium hyaluronate into an emulsifying pot, uniformly dispersing, stirring and heating to 85-88 ℃, and homogenizing for 3-5 minutes until the components are completely and uniformly dissolved without particles;

s3, adding the mixture obtained in the S1 into the emulsifying pot, homogenizing for 3-5 minutes, preserving heat for 20 minutes, stirring and cooling to 65 ℃;

s4, independently heating the residual butanediol and the antioxidant to 60-65 ℃, stirring and dissolving the residual butanediol and the antioxidant completely and transparently without particles, adding the mixture into an emulsifying pot when the temperature of a material body in the emulsifying pot is reduced to 65 ℃, uniformly stirring, adding a mixed solution of a pH regulator and a partial solvent which are dissolved completely and transparently without particles in advance, and uniformly stirring;

s5, continuously stirring and cooling to below 45 ℃, sequentially adding 1, 2-hexanediol, octyldodecanol, echeveria oil, sunflower seed oil unsaponifiable matter, ardisia japonica extract, tocopherol and aromatic, and uniformly stirring;

s6, adding a mixture of 9: 1, and uniformly stirring the mixture of rhamnose and the solvent to obtain the product.

Compared with the prior art, the invention has the beneficial effects that: the traditional PEG emulsifier is abandoned, the plant-source degradable polyglycerol emulsifier is used for forming the stable oil-in-water cream, the system is organic and natural, mild and non-irritant, the natural emollients such as shea butter, phytosterol, coco oil alcohol-caprylate/caprate and the like are matched with the active substances such as the echium japonicum seed oil and the sunflower seed oil unsaponifiable substance, the skin barrier is effectively strengthened and consolidated, the reaction of the skin to external irritation is reduced by the addition of the ardisia japonica extract and rhamnose, and the effects of preventing the skin of infants from being hypersensitive and providing the skin with instant relief are achieved.

Drawings

Fig. 1 is a picture of a finished baby skin cream composition without a PEG emulsifier.

Detailed Description

The technical solution of the present patent will be described in further detail with reference to the following embodiments.

The raw material sources of the components in the PEG-free emollient cream composition for infants and children are shown in Table 1

TABLE 1

Example 1

A PEG emulsifier-free skin moistening cream composition for infants and children is prepared from the following components in percentage by weight: polyglycerol-3-methylglucose distearate 2.5%, polyglycerol-3-distearate 1.14%, glycerol stearate citrate 0.06%, thickening stabiliser 1.5%, palmitic acid 0.6%, stearic acid 0.4%, shea butter 2%, glycerol tri (ethylhexanoate) 5%, isopropyl myristate 4%, phytosterol isostearate 0.5%, coco-caprylate/caprate 3%, polydimethylsiloxane 3%, thickener 0.25%, butylene glycol 5%, glycerin 5%, sodium hyaluronate 0.06%, 1, 2-hexanediol 0.5%, co-emulsifier 0.3%, allantoin 0.2%, octyldodecanol 0.9385%, echium oil 0.05%, sunflower seed oil unsaponifiable 0.01%, illicium extract 0.001%, tocopherol 0.0005%, rhamnose 0.9%, antioxidant 0.5%, pH adjuster 0.18%, fragrance 0.15%, and, The solvent is the rest.

The preparation method of the PEG-free skin-moistening cream composition for infants comprises the following steps:

s1, adding the emulsifier, the thickening stabilizer, the emollient and the emollient into an oil pan, stirring and heating to 80 ℃ until the emulsifier, the thickening stabilizer, the emollient and the emollient are completely dissolved and no particles exist for later use;

s2, adding a thickening agent, a solvent accounting for 10% of the total amount of the solvent, butanediol accounting for 15% of the total amount of the butanediol, an auxiliary emulsifier, glycerol, allantoin and sodium hyaluronate into an emulsifying pot, uniformly dispersing, stirring and heating to 85 ℃, and homogenizing for 3 minutes until the components are completely and uniformly dissolved and no particles exist;

s3, adding the mixture obtained in the S1 into the emulsifying pot, homogenizing for 3 minutes, preserving heat for 20 minutes, stirring and cooling to 65 ℃;

s4, independently heating the residual butanediol and the antioxidant to 60 ℃, stirring and dissolving the residual butanediol and the antioxidant completely and transparently without particles, adding the mixture into an emulsifying pot when the temperature of a material body in the emulsifying pot is reduced to 65 ℃, uniformly stirring the mixture, adding a mixed solution of a pH regulator and a partial solvent which are dissolved completely and transparently without particles in advance, and uniformly stirring the mixture;

s5, continuously stirring and cooling to below 45 ℃, sequentially adding 1, 2-hexanediol, octyldodecanol, echeveria oil, sunflower oil unsaponifiable matter, fructus seu radix camptothecae acuminatae extract, tocopherol and aromatic, and uniformly stirring;

s6, adding a mixture of 9: 1, and uniformly stirring the mixture of rhamnose and the solvent to obtain the product.

Example 2

A PEG-emulsifier-free skin-moistening cream composition for infants and children is prepared from the following components in percentage by weight: polyglycerol-3-methylglucdistearate 2.5%, polyglycerol-3-distearate 0.89%, glycerol stearate citrate 0.04%, thickening stabiliser 1.0%, palmitic acid 0.4%, stearic acid 0.3%, shea butter 0.8%, glycerol tri (ethylhexanoate) 3.8%, isopropyl myristate 2.3%, phytosterol isostearate 0.35%, coco-caprylate/caprate 1.8%, dimethicone 2.9%, thickener 0.11%, butylene glycol 4.3%, glycerol 5%, sodium hyaluronate 0.06%, 1, 2-hexanediol 0.48%, co-emulsifier 0.2%, allantoin 0.01%, octyldodecanol 0.05%, echium oil 0.04%, sunflower seed oil unsaponifiable 0.01%, retrogradation extract 0.001%, tocopherol 0.0005%, rhamnose 0.01%, antioxidant 0.2%, pH regulator 0.01%, fragrance 0.01% >, fragrance, The solvent is the rest.

The preparation method of the PEG-free skin-moistening cream composition for infants comprises the following steps:

s1, adding the emulsifier, the thickening stabilizer, the emollient and the emollient into an oil pan, stirring and heating to 80 ℃ until the emulsifier, the thickening stabilizer, the emollient and the emollient are completely dissolved and have no particles for later use;

s2, adding a thickening agent, a solvent accounting for 10% of the total amount of the solvent, butanediol accounting for 15% of the total amount of the butanediol, an auxiliary emulsifier, glycerol, allantoin and sodium hyaluronate into an emulsifying pot, uniformly dispersing, stirring and heating to 85 ℃, and homogenizing for 3 minutes until the components are completely and uniformly dissolved and no particles exist;

s3, adding the mixture obtained in the S1 into the emulsifying pot, homogenizing for 3 minutes, preserving heat for 20 minutes, stirring and cooling to 65 ℃;

s4, independently heating the residual butanediol and the antioxidant to 60 ℃, stirring and dissolving the residual butanediol and the antioxidant completely and transparently without particles, adding the mixture into an emulsifying pot when the temperature of a material body in the emulsifying pot is reduced to 65 ℃, uniformly stirring the mixture, adding a mixed solution of a pH regulator and a partial solvent which are dissolved completely and transparently without particles in advance, and uniformly stirring the mixture;

s5, continuously stirring and cooling to below 45 ℃, sequentially adding 1, 2-hexanediol, octyldodecanol, echeveria oil, sunflower seed oil unsaponifiable matter, ardisia japonica extract, tocopherol and aromatic, and uniformly stirring;

s6, adding a mixture of 9: 1, and uniformly stirring the mixture of rhamnose and the solvent to obtain the product.

Example 3

A PEG-emulsifier-free skin-moistening cream composition for infants and children is prepared from the following components in percentage by weight: polyglycerol-3-methylglucdistearate 3.8%, polyglycerol-3-distearate 1.14%, glycerol stearate citrate 0.06%, thickening stabiliser 1.5%, palmitic acid 0.6%, stearic acid 0.4%, shea butter 2%, glycerol tri (ethylhexanoate) 5%, isopropyl myristate 4%, phytosterol isostearate 0.5%, coco-caprylate/caprate 3%, polydimethylsiloxane 3%, thickener 0.25%, butylene glycol 5%, glycerol 9%, sodium hyaluronate 0.07%, 1, 2-hexanediol 0.5%, co-emulsifier 0.3%, allantoin 0.2%, octyldodecanol 0.9385%, echium oil 0.05%, sunflower seed oil unsaponifiable 0.01%, illicium extract 0.001%, tocopherol 0.0005%, rhamnose 0.9%, antioxidant 0.5%, pH adjuster 0.18%, fragrance 0.15%, and, The solvent is the rest.

The preparation method of the PEG-free skin-moistening cream composition for infants comprises the following steps:

s1, adding the emulsifier, the thickening stabilizer, the emollient and the emollient into an oil pan, stirring and heating to 80 ℃ until the emulsifier, the thickening stabilizer, the emollient and the emollient are completely dissolved and no particles exist for later use;

s2, adding a thickening agent, a solvent accounting for 10% of the total amount of the solvent, butanediol accounting for 15% of the total amount of the butanediol, an auxiliary emulsifier, glycerol, allantoin and sodium hyaluronate into an emulsifying pot, uniformly dispersing, stirring and heating to 85 ℃, and homogenizing for 3 minutes until the components are completely and uniformly dissolved and no particles exist;

s3, adding the mixture obtained in the S1 into the emulsifying pot, homogenizing for 3 minutes, preserving heat for 20 minutes, stirring and cooling to 65 ℃;

s4, independently heating the residual butanediol and the antioxidant to 60 ℃, stirring and dissolving the residual butanediol and the antioxidant completely and transparently without particles, adding the mixture into an emulsifying pot when the temperature of a material body in the emulsifying pot is reduced to 65 ℃, uniformly stirring the mixture, adding a mixed solution of a pH regulator and a partial solvent which are dissolved completely and transparently without particles in advance, and uniformly stirring the mixture;

s5, continuously stirring and cooling to below 45 ℃, sequentially adding 1, 2-hexanediol, octyldodecanol, echeveria oil, sunflower oil unsaponifiable matter, fructus seu radix camptothecae acuminatae extract, tocopherol and aromatic, and uniformly stirring;

s6, adding a mixture of 9: 1, and uniformly stirring the mixture of rhamnose and the solvent to obtain the product.

Test detection

The product obtained in example 1 was tested according to the technical specifications for cosmetic safety (2015 edition) and the results are as follows: and (3) microbial detection: the total number of bacterial colonies, the total number of moulds and yeasts, the heat-resistant coliform group and the staphylococcus aureus pseudomonas aeruginosa meet the requirements of technical specifications for cosmetic safety (2015 edition).

(II) physical and chemical inspection: the contents of mercury, lead, arsenic, cadmium and dioxane meet the requirements of technical Specification for safety of cosmetics (2015 edition).

(III) toxicology test

Experimental animals: 2 common-grade New Zealand rabbits, 2 male rabbits and 22 female rabbits, the weight of 2.0-2.2kg, the production license number of experimental animals: SCXK (zhe) 2018-: 20211114Cdez 0606999889.

The experimental method comprises the following steps: the rabbits were allowed to adapt to the animal house for 4 days before the test, and 4 healthy rabbits with no skin damage were removed, and both sides of the spinal column of the back were shaved 24 hours before the test, each of the left and right was 3cm × 3cm, 0.5mL of the test substance was directly applied to the skin on the left side, the application area was 2.5cm × 2.5cm, and the skin on the other side was not treated as a control. The product is applied once a day for 14 days. From the next day, the remaining test substance was removed with warm water before each application, and the newly grown hairs were cut off. The skin reaction at the applied site was observed after 1 hour after the removal of the residual test substance, and was scored according to "skin irritation response score" in "skin irritation/corrosion test" of technical Specification for cosmetic safety (2015 edition). The control and test zones were treated the same way and the results are shown in Table 2.

TABLE 2

The working principle is as follows: the invention provides a PEG-emulsifier-free baby skin-moistening cream composition and a preparation method thereof, the traditional PEG emulsifier is abandoned, the plant-source degradable polyglycerol emulsifier is used for forming stable oil-in-water cream, the system is organic, natural, mild and non-irritant, the natural emollients of shea butter, phytosterol, coconut oil alcohol-caprylate/caprate and the like are matched with the active substances of Echium oil, sunflower seed oil unsaponifiable substances and the like, the skin barrier is effectively strengthened and consolidated, and the reaction of skin to external stimulation is reduced by the addition of the ardisia japonica extract and rhamnose, so that the effects of preventing the skin of babies from being hypersensitive and providing the skin with instant relief are achieved.

Claims (8)

1. The PEG-emulsifier-free skin cream composition for infants and children is characterized by comprising the following components: emulsifiers, thickening stabilizers, emollients, thickeners, humectants, co-emulsifiers, skin conditioners, antioxidants, pH adjusters, fragrances, solvents;

the emulsifier comprises polyglyceryl-3-methylglucdistearate, polyglyceryl-3-distearate, glyceryl stearate citrate.

2. The PEG emulsifier free baby skin cream composition as claimed in claim 1, wherein the skin conditioning agent comprises allantoin, octyldodecanol, echium oil, sunflower oil unsaponifiable matter, extract of Ardisia japonica, tocopherol, rhamnose.

3. The PEG emulsifier free skin cream composition for infants and children according to claim 2, wherein the emollient comprises palmitic acid, stearic acid.

4. A PEG emulsifier free baby skin cream composition according to claim 3, wherein the emollient comprises shea butter, glycerol tri (ethyl hexanoate), isopropyl myristate, phytosterol isostearate, coco-caprylate/caprate, dimethicone.

5. The PEG emulsifier free skin cream composition for infants and children according to claim 4, wherein the humectant comprises butylene glycol, glycerin, sodium hyaluronate, 1, 2-hexanediol.

6. The PEG emulsifier-free baby skin cream composition according to claim 5, which is prepared from the following components in percentage by weight: 2.5 to 3.8 percent of polyglycerol-3-methyl glucose distearate, 0.89 to 1.14 percent of polyglycerol-3 distearate, 0.04 to 0.06 percent of glycerol stearate citrate, 1.0 to 1.5 percent of thickening stabilizer, 0.4 to 0.6 percent of palmitic acid, 0.3 to 0.4 percent of stearic acid, 0.8 to 2 percent of shea butter, 3.8 to 5 percent of glycerol tri (ethyl hexanoate), 2.3 to 4 percent of isopropyl myristate, 0.35 to 0.5 percent of phytosterol isostearate, 1.8 to 3 percent of coco-caprylate/caprate, 2.9 to 3 percent of polydimethylsiloxane, 0.11 to 0.25 percent of thickening agent, 4.3 to 5 percent of butanediol, 5 to 9 percent of glycerol, 0.06 to 0.07 percent of sodium hyaluronate, and 0.48 to 0.5 percent of 1, 2-hexanediol, 0.2-0.3% of co-emulsifier, 0.01-0.2% of allantoin, 0.05-0.9385% of octyl dodecanol, 0.04-0.05% of cynara scolymus seed oil, 0.01% of sunflower seed oil unsaponifiable matter, 0.001% of ardisia japonica extract, 0.0005% of tocopherol, 0.01-0.9% of rhamnose, 0.2-0.5% of antioxidant, 0.01-0.18% of pH regulator, 0.01-0.15% of aromatic and the balance of solvent.

7. The PEG emulsifier free skin cream composition for infants and children according to claim 6, which is prepared from the following components in percentage by weight: polyglycerol-3-methylglucdistearate 2.5%, polyglycerol-3-distearate 1.14%, glycerol stearate citrate 0.06%, thickening stabiliser 1.5%, palmitic acid 0.6%, stearic acid 0.4%, shea butter 2%, glycerol tri (ethylhexanoate) 5%, isopropyl myristate 4%, phytosterol isostearate 0.5%, coco-caprylate/caprate 3%, polydimethylsiloxane 3%, thickener 0.25%, butylene glycol 5%, glycerol 5%, sodium hyaluronate 0.06%, 1, 2-hexanediol 0.5%, co-emulsifier 0.3%, allantoin 0.2%, octyldodecanol 0.9385%, echium oil 0.05%, sunflower seed oil unsaponifiable 0.01%, illicium extract 0.001%, tocopherol 0.0005%, rhamnose 0.9%, antioxidant 0.5%, pH adjuster 0.18%, fragrance 0.15%, and, The solvent is the rest.

8. A method of preparing a PEG emulsifier free skin cream composition for infants and children according to any one of claims 6 to 7, comprising the steps of:

s1, adding the emulsifier, the thickening stabilizer, the emollient and the emollient into an oil pan, stirring and heating to 80-85 ℃ until the emulsifier, the thickening stabilizer, the emollient and the emollient are completely dissolved and no particles exist for later use;

s2, adding a thickening agent, a solvent accounting for 10% of the total amount of the solvent, butanediol accounting for 15% of the total amount of the butanediol, an auxiliary emulsifier, glycerol, allantoin and sodium hyaluronate into an emulsifying pot, uniformly dispersing, stirring and heating to 85-88 ℃, and homogenizing for 3-5 minutes until the components are completely and uniformly dissolved without particles;

s3, adding the mixture obtained in the S1 into the emulsifying pot, homogenizing for 3-5 minutes, preserving heat for 20 minutes, stirring and cooling to 65 ℃;

s4, independently heating the residual butanediol and the antioxidant to 60-65 ℃, stirring and dissolving the residual butanediol and the antioxidant completely and transparently without particles, adding the mixture into an emulsifying pot when the temperature of a material body in the emulsifying pot is reduced to 65 ℃, uniformly stirring, adding a mixed solution of a pH regulator dissolved completely and transparently without particles and 10 parts of solvent, and uniformly stirring;

s5, continuously stirring and cooling to below 45 ℃, sequentially adding 1, 2-hexanediol, octyldodecanol, echeveria oil, sunflower seed oil unsaponifiable matter, ardisia japonica extract, tocopherol and aromatic, and uniformly stirring;

s6, adding a mixture of 9: 1 and uniformly stirring the mixture of rhamnose and the solvent to obtain the product.

Images