CN115054641A - Scraping medicinal oil and preparation method thereof - Google Patents

Scraping medicinal oil and preparation method thereof Download PDF

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Publication number
CN115054641A
CN115054641A CN202210718760.0A CN202210718760A CN115054641A CN 115054641 A CN115054641 A CN 115054641A CN 202210718760 A CN202210718760 A CN 202210718760A CN 115054641 A CN115054641 A CN 115054641A
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parts
scraping
traditional chinese
chinese medicine
raw materials
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CN115054641B (en
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来玉芹
郭钦源
牛聪
覃周韦
薛丹
覃彩芳
覃璇
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Liuzhou Maternity and Child Healthcare Hospital
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Liuzhou Maternity and Child Healthcare Hospital
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H7/00—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
    • A61H7/002—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing
    • A61H7/004—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing power-driven, e.g. electrical
    • A61H7/005—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing power-driven, e.g. electrical hand-held
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/537—Salvia (sage)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation, and provides a scraping medicinal oil and a preparation method thereof, wherein the effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials comprise the following raw materials in parts by weight: 25-35 parts of bighead atractylodes rhizome, 25-35 parts of poria cocos, 25-35 parts of Chinese angelica, 25-35 parts of astragalus membranaceus, 18-22 parts of ligusticum wallichii, 25-35 parts of radix rehmanniae recen, 8-12 parts of cassia twig, 18-22 parts of radix paeoniae alba, 18-22 parts of semen cuscutae, 18-22 parts of eucommia ulmoides, 18-22 parts of salvia miltiorrhiza and 18-22 parts of liquorice. The medicinal oil disclosed by the invention has the effects of tonifying spleen and qi, nourishing blood and essence, whitening and removing freckles, and can effectively assist in improving the female facial stain problem.

Description

Scraping medicinal oil and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a scraping medicinal oil and a preparation method thereof.
Background
The skin scraping is guided by the theory of traditional Chinese medicine meridian and acupoints, and is performed by repeatedly scraping and rubbing the body surface with a special scraping device and corresponding manipulations to make local skin appear red marbled grains or dark red bleeding spots and other 'eruption changes', thereby achieving the effect of activating blood circulation and promoting eruption. Because of its characteristics of simplicity, convenience, low cost and effectiveness, it has extensive clinical application, and is suitable for medical treatment and family health care. The scraping therapy has the effects of promoting blood circulation, removing blood stasis, dredging channels and collaterals, and regulating immunity, and is suitable for various diseases of internal, external, women, children, etc., especially pain diseases.
The skin is damaged by the scraping therapy, so before scraping, a layer of lubricating oil is coated on the surface of the skin to prevent the skin from being scratched. The main two types of lubricating oil for scraping therapy are provided, one type is a scraping therapy medium which has a simple lubricating effect, such as vegetable oil; the other is the scraping medicinal oil with medical treatment effect, such as safflower oil, traumatic injury oil, rheumatism oil and the like, and the scraping medicinal oil has the lubricating effect, prevents the skin from being damaged by the scraping plate, and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, diminishing inflammation, relieving pain and the like.
With the accelerated pace of life, the women who stay up and age up tend to have chloasma, which is called liver spots and blackish black spots in traditional Chinese medicine, mainly appear on the yellow brown and black pigmentation of the face, which not only affects the beauty of the face, but also brings troubles and pains in various aspects of physiology, psychology, spirit and the like. Although chloasma is a facial disease, the chloasma is mostly related to dysfunction of the liver, spleen and kidney, and the traditional Chinese medicine considers that the liver fails to reach the state, the qi activity is stagnated, the stagnation is changed into fire for a long time, yin and blood are burned, the blood circulation is unsmooth, and the facial qi-blood disharmony can be caused; spleen qi is weak, transportation and transformation fail to generate essence, so qi and blood can not moisten face; chloasma can be caused on the face due to pathological changes such as kidney yang deficiency and kidney essence deficiency.
The scraping therapy can not only make qi and blood flow smoothly, strengthen the performance of viscera, further enhance the immunity of skin, but also improve the problem skin. However, the types of the existing scraping medicinal oil are few, the basic function of the oil as a medium for lubrication is the main, and the scraping medicinal oil for promoting blood circulation, whitening and removing freckles in gynecological clinical application is few.
Disclosure of Invention
The invention aims to: aiming at the problems, the invention provides the scraping medicinal oil and the preparation method thereof, and the medicinal oil has the effects of tonifying spleen and qi, nourishing blood and replenishing vital essence, and whitening and removing freckles, and can effectively assist in improving the female facial color spots.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, wherein the traditional Chinese medicine raw materials comprise the following raw materials in parts by weight: 25-35 parts of bighead atractylodes rhizome, 25-35 parts of poria cocos, 25-35 parts of Chinese angelica, 25-35 parts of astragalus membranaceus, 18-22 parts of ligusticum wallichii, 25-35 parts of radix rehmanniae recen, 8-12 parts of cassia twig, 18-22 parts of radix paeoniae alba, 18-22 parts of semen cuscutae, 18-22 parts of eucommia ulmoides, 18-22 parts of salvia miltiorrhiza and 18-22 parts of liquorice.
The preparation method of the scraping medicinal oil comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials in parts by weight;
(2) pulverizing the Chinese medicinal materials into powder to obtain Chinese medicinal powder;
(3) soaking the Chinese medicinal powder in oleum Camelliae for extraction;
(4) filtering and removing filter residues to obtain the scraping medicinal oil.
Preferably, the traditional Chinese medicine powder is powder sieved by a sieve of 80-120 meshes.
Preferably, in the step (3), the mass-to-volume ratio of the traditional Chinese medicine powder to the tea oil is 450-550 g: 4L of the reaction solution.
Preferably, in step (3), the soaking extraction time is 12 hours or more.
In the formula, the action principle of each medicine is as follows:
bighead atractylodes rhizome is warm in nature, sweet and bitter in taste, and has the functions of tonifying spleen and invigorating stomach, eliminating dampness and promoting diuresis, stopping sweating and preventing miscarriage and the like. The book of drug properties states that the recipe is "main facial pleasing, youthful looks and wild. Modern pharmacological studies have also confirmed the cosmetic effects of white atractylodes rhizome: atractylodis rhizoma can enhance immunity and dilate blood vessel. It has inhibitory effect on dermatophytosis such as dermatophytosis. Ancient book "medical property treatise": "have beautiful main face, retain youthful looks and remove spots. White atractylodes rhizome is dipped in wine (or vinegar) in the form of ground ink and is uniformly applied to the face, so that the face-beautifying wine can whiten the skin, clear heat and dry dampness, kill mites and remove acnes, and can treat freckles and black spots.
Bai Fu Ling is sweet and bland in flavor. Promoting diuresis, eliminating dampness, invigorating spleen, regulating stomach function, calming heart, and tranquilizing mind. Meanwhile, the medicine also has the effects of clearing away heat and toxic materials, removing some necrotic cells of a human body and promoting the metabolic cycle of the human body. The white poria has the effects of removing freckles and acnes, whitening and moistening skin and the like. The book of materia medica Hui Jing Yao records that white poria is powder and mixed with honey, and the powder is applied on a face to treat face sores and puerpera black blisters like sparrow eggs. "
The angelica sinensis is sweet and pungent in flavor and warm in nature, enters liver, heart and spleen channels, and has the effects of enriching and activating blood, regulating menstruation and relieving pain, and relaxing bowel. Astragalus root, radix astragali, sweet in flavor, slightly warm in nature, enters lung and spleen channels, and has effects of invigorating qi, invigorating yang, promoting fluid production, nourishing blood, consolidating superficial resistance, arresting sweating, activating stagnancy, relieving arthralgia, inducing diuresis, relieving swelling, expelling pus, healing sore and promoting granulation. Radix astragali mainly contains compounds such as flavonoids, saponins and polysaccharides, and radix Angelicae sinensis mainly contains volatile oils and organic acids represented by lactones. Radix astragali has effects of relieving inflammation, regulating immunity, resisting aging and virus, protecting cardiovascular and cerebrovascular, inhibiting proliferation of cells such as hepatocarcinoma and lung cancer, and lowering blood sugar. The angelica has good functions of improving anemia, protecting liver, regulating immunity, resisting tumor, resisting inflammation, promoting blood circulation and the like. The inhibition effect of the angelica essential oil and the ligustilide on bacteria is better than that of fungi, and the inhibition effect on gram-positive bacteria is better than that of gram-negative bacteria; the two substances have basically consistent antibacterial effect, and ligustilide has important effect on antibacterial property of radix Angelicae sinensis essential oil. The astragalus-angelica has the functions of regulating immunity, improving blood circulation, resisting oxidation, resisting organ fibrosis, resisting inflammation, resisting tumor and the like, has wide clinical application, is mainly used for treating kidney syndrome, diabetic lesion, anemia and the like, and obtains good curative effect.
Chuan Xiong is listed as the top grade in Shen nong Ben Cao Jing (Shen nong's herbal). It has thick fragrance, warm nature, bitter and pungent taste, and has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind, relieving pain, dispersing stagnated liver qi, and relieving qi stagnation. Chuan Xiong from Ben Cao Hui Yan (materia Medica) is a herb for descending and regulating menstruation, resolving stagnation and regulating qi in blood. When tasting Dang Gui, it is not the first to treat blood and active, but also to treat qi, it is also verified that … … is pungent and yang-natured, and qi moves well without yin congealing and sticky stagnation, and although entering blood system, it can remove one wind and regulate all qi. The summary of the Chinese materia medica shows that the chuanxiong rhizome, pungent in flavor and warm in nature, enters liver, gallbladder and pericardium channels, has the effects of activating blood and promoting qi circulation, dispelling wind and relieving pain, and has the action characteristics of activating blood and dissolving stasis, promoting qi and blood circulation, and promoting qi circulation and relieving pain, and is a qi medicine in blood.
Radix rehmanniae is cold in nature and sweet in taste, and has the effects of clearing heat and cooling blood, and nourishing yin and promoting the production of body fluid. Modern pharmacology indicates that radix rehmanniae has good effects of reducing blood sugar, resisting aging, protecting liver and the like. Studies show that the dried rehamnnia root-tree peony bark-liquorice root is the core compatibility for treating psoriasis vulgaris. Research shows that the radix rehmanniae, the tree peony bark and the liquorice can play roles of inducing apoptosis, resisting inflammation and resisting oxidation through flavonoid active component monomers such as quercetin, kaempferol and the like, and play a role in treating psoriasis vulgaris through signal channels such as STAT3, TNF and the like.
Cassia twig, pungent, sweet and warm in property, entering heart, lung and bladder meridians, has the functions of inducing sweat, relieving muscles, warming and dredging channels and collaterals, supporting yang, regulating qi and calming the Chong and descending qi, and is recorded in the herbal refreshment for treating symptoms of cold numbness of hands and feet, pain of tendons and muscles, cold and cool external infection and the like. The traditional Chinese medicine composition is mainly used for treating wind-cold-dampness arthralgia clinically, and has the effects of expelling wind and clearing away cold, clearing heat and eliminating phlegm, and stimulating the menstrual flow and activating blood circulation. The main effective component is volatile oil, the main component of the oil is cinnamaldehyde, and the oil has pharmacological effects of expanding blood vessels, promoting sweating, relieving fever and pain, resisting inflammation, resisting allergy and the like through research. It is used for preventing influenza and rheumatic arthritis. The chemical component research on the cassia twig so far shows that 121 compounds are separated and identified from the cassia twig, and the main chemical components are phenylpropanoids, terpenoids, flavones, glycosides thereof, volatile oil, organic acids, steroids, phenolic acids and lactones. The research on the pharmacological activity of the cassia twig at home and abroad shows that the cassia twig has the functions of anti-inflammation, antibiosis, anti-tumor, anti-obesity, antivirus, anti-depression, neuroprotection and vasodilation.
White peony root, radix Paeoniae alba is bitter, sour and slightly cold in taste, enters liver and spleen meridians, nourishes blood and regulates menstruation, calms the liver to relieve pain, astringes yin and stops sweating. The main effective components are paeoniflorin, paeonol, paeoniflorin and the like, and the paeoniflorin has pharmacological effects of resisting inflammation, regulating immunity, tranquilizing, resisting convulsion, relieving fever, relieving spasm and the like through research. The total glucosides of paeony capsules belong to a glucoside immunoregulation medicament, are extracted from Chinese medicinal white paeony roots, consist of active ingredients such as albiflorin, hydroxy paeoniflorin and the like, have the effects of immunoregulation, inflammation resistance, pain relief and the like, and have a certain liver protection effect. Studies find that the total glucosides of paeony can improve the clinical symptoms of osteoarthritis and reduce inflammatory reaction.
The dodder seed is pungent and sweet in flavor and slightly warm in nature, enters liver and kidney channels, and has the effects of tonifying kidney and replenishing vital essence, nourishing liver and improving eyesight, preventing miscarriage and stopping diarrhea. It is a good herb for tonifying liver and kidney, beginning with the Shen nong Ben Cao Jing, its property of medicine is neutral, sweet and pungent with mild temperature, entering liver, kidney and spleen meridians. The semen Cuscutae mainly comprises flavonoids, polysaccharides, alkaloids, terpenes, steroids, volatile oil and lignin. Has good clinical curative effects in preventing miscarriage, relieving reproductive toxicity, and treating oligospermia, asthenospermia, premature ovarian failure, kidney-yang deficiency, osteoporosis and the like, and has certain curative effects on vitiligo and senile dementia.
Du Zhong is slightly qi and slightly bitter in taste, recorded in Ben Cao gang mu, it has the actions of treating pain in waist and knees, tonifying middle-jiao and replenishing essence, strengthening tendons and bones, and strengthening will. Eucommia ulmoides contains various active ingredients, namely eucommia ulmoides bark, eucommia ulmoides leaves and eucommia ulmoides flowers. Researches show that the eucommia bark mainly contains lignans compounds, the eucommia leaves are rich in iridoids, phenols and flavonoids compounds, and the eucommia flower mainly contains flavonoids compounds. Eucommia bark contains rich chemical components including iridoid, lignanoid, flavonoid, phenylpropanoids, polysaccharide and the like, and has obvious effects of reducing blood sugar, blood pressure and blood fat, resisting osteoporosis, resisting oxidation, regulating immunity, resisting inflammation, inhibiting bacteria and the like. The cortex Eucommiae extract can be used for enhancing osteogenic differentiation of bone marrow mesenchymal stem cells by regulating serum Osteoprotegerin (OPG) and receptor activator of nuclear factor ligand (RANKL) level.
Salvia miltiorrhiza has the effects of removing blood stasis, promoting tissue regeneration, promoting blood circulation, regulating menstruation and the like, is a key gynecological medicine and is mainly used for treating metrorrhagia, irregular menstruation, blood stasis, abdominal pain, menstrual pain, amenorrhea and temple pain.
Licorice root, radix Glycyrrhizae is sweet and neutral in nature, and enters heart, lung, spleen and stomach meridians. Has effects in invigorating spleen, invigorating qi, clearing away heat and toxic materials, expelling phlegm, relieving cough, relieving spasm and pain, and harmonizing the drugs. In the Shen nong Ben Cao Jing, the herb is listed as the superior of the herbs, and the Tao hong Jing honors the liquorice as the "aged", which says that the herb is the most popular herb and rarely used in the Jing Fang. Research proves that the peony and licorice decoction has the functions of spasmolysis, analgesia, anti-inflammation, anti-allergic reaction and the like.
The tea oil is also called camellia oil and camellia seed oil, is high-grade edible oil obtained by processing camellia seeds which are fruits of woody oil plants camellia in China, is known as 'east olive oil', has the contents of oleic acid and vitamin E which are respectively 7 percent higher and 1 time higher than that of the olive oil, and has the reputations of 'longevity oil', 'king in oil' and the like. The tea oil has good medical care function.
Through clinical observation, the inventor of the application finds that the pathogenesis of chloasma is liver dysfunction, qi stagnation, long-time stagnation, fire transformation, yin blood burn and unsmooth blood circulation, and facial qi and blood disharmony can be caused; spleen qi is weak, transportation and transformation are disabled, and essence cannot be generated, so that qi and blood cannot moisten face; chloasma can be caused on the face due to pathological changes such as kidney yang deficiency and kidney essence deficiency. The traditional Chinese medicine composition has the advantages that through the mutual matching of the medicines in the prescription, the spleen and the qi are strengthened and supplemented through the bighead atractylodes rhizome, the poria cocos, the astragalus mongholicus and the liquorice, the transportation and transformation capacity of the spleen is improved, the essence and the tiny are provided for improving qi and blood, and the qi and the blood are transported and distributed to the whole body through invigorating qi and invigorating yang; the Chinese angelica, the white paeony root, the dried rehmannia root and the eucommia bark can nourish blood and replenish vital essence and replenish qi and blood; the blood circulation is promoted and the blood stasis is removed through the hemlock parsley, the cassia twig and the salvia miltiorrhiza, so that the blood circulation is smooth; tonifying kidney and replenishing vital essence through semen cuscutae; a plurality of medicines jointly achieve the effects of improving the body function, removing stasis, whitening and removing freckles. Combined with the scraping therapy, the effective components can be effectively absorbed, the skin irritation is reduced, the skin circulation is improved, and the curative effect is enhanced.
The scraping medicinal oil is used for scraping color spots of patients, and is matched with back, face and limbs for 1-3 times per week. 7-10 times of treatment is one treatment course, and two treatment courses are used, so that remarkable effect is achieved.
In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:
1. the skin scraping medicinal oil disclosed by the invention can play a good lubricating role in the skin scraping process, has good effects of tonifying spleen and qi, nourishing blood and replenishing vital essence, enhancing local blood circulation and whitening and removing freckles through a transdermal effect, is externally used without toxic or side effect, can be used as a skin scraping medium to synergistically enhance the curative effect of the skin scraping, and is a good product for preventing and treating diseases; solves the technical problem of limited curative effect of the scraping medical oil which only plays a role of lubrication in the prior art.
2. The invention provides a new treatment scheme for treating chloasma, has no gastrointestinal reaction caused by oral administration of traditional Chinese medicines, and can enhance the curative effect by scraping.
Detailed Description
In order that the invention may be more clearly expressed, the invention is further illustrated by the following specific examples.
Example 1
The effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials comprise the following raw materials in parts by weight: 25g of bighead atractylodes rhizome, 35g of poria cocos, 25g of Chinese angelica, 35g of astragalus membranaceus, 18g of ligusticum wallichii, 35g of radix rehmanniae recen, 8g of cassia twig, 22g of radix paeoniae alba, 18g of semen cuscutae, 22g of eucommia ulmoides, 18g of salvia miltiorrhiza and 22g of liquorice.
The preparation method of the scraping medicinal oil comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials in parts by weight;
(2) pulverizing the Chinese medicinal materials into powder, and sieving with 80 mesh sieve to obtain Chinese medicinal powder;
(3) soaking and extracting traditional Chinese medicine powder by using tea oil, wherein the mass volume ratio of the traditional Chinese medicine powder to the tea oil is 450 g: 4L, soaking and extracting for 24 h;
(4) filtering and removing filter residues to obtain the scraping medicinal oil.
Example 2
The effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials comprise the following raw materials in parts by weight: 30g of bighead atractylodes rhizome, 30g of poria cocos, 30g of Chinese angelica, 30g of astragalus membranaceus, 20g of ligusticum wallichii, 30g of radix rehmanniae recen, 10g of cassia twig, 20g of radix paeoniae alba, 20g of semen cuscutae, 20g of eucommia ulmoides, 20g of salvia miltiorrhiza and 20g of liquorice.
The preparation method of the scraping medicinal oil comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials in parts by weight;
(2) pulverizing the Chinese medicinal materials into powder, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(3) soaking and extracting traditional Chinese medicine powder by using tea oil, wherein the mass volume ratio of the traditional Chinese medicine powder to the tea oil is 400 g: 4L, soaking and extracting for 36 h;
(4) filtering and removing filter residues to obtain the scraping medicinal oil.
Example 3
The effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials comprise the following raw materials in parts by weight: 35g of bighead atractylodes rhizome, 25g of poria cocos, 35g of Chinese angelica, 25g of astragalus membranaceus, 22g of ligusticum wallichii, 35g of radix rehmanniae recen, 8g of cassia twig, 22g of radix paeoniae alba, 18g of semen cuscutae, 22g of eucommia ulmoides, 22g of salvia miltiorrhiza and 18g of liquorice.
The preparation method of the scraping medicinal oil comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials in parts by weight;
(2) pulverizing the traditional Chinese medicine raw materials into powder, and sieving the powder with a 120-mesh sieve to obtain traditional Chinese medicine powder;
(3) soaking and extracting traditional Chinese medicine powder by using tea oil, wherein the mass volume ratio of the traditional Chinese medicine powder to the tea oil is 500 g: 4L, soaking and extracting for 48 h;
(4) filtering and removing filter residues to obtain the scraping medicinal oil.
Comparative example 1
The effective components of the scraping medicinal oil are from traditional Chinese medicine raw materials, and the medicinal oil is composed of the following raw materials in parts by weight: 30g of bighead atractylodes rhizome, 30g of poria cocos, 30g of Chinese angelica, 30g of astragalus membranaceus, 20g of ligusticum wallichii, 30g of radix rehmanniae recen, 20g of radix paeoniae alba, 20g of semen cuscutae and 20g of salvia miltiorrhiza. Compared with example 2, no radix astragali, ramulus Cinnamomi, and cortex Eucommiae were added. The preparation method is the same as that of example 2.
Comparative example 2
The effective components of the scraping medicinal oil are from traditional Chinese medicine raw materials, and the medicinal oil is composed of the following raw materials in parts by weight: 20g of bighead atractylodes rhizome, 20g of poria cocos, 20g of Chinese angelica, 20g of astragalus membranaceus, 20g of ligusticum wallichii, 30g of radix rehmanniae recen, 10g of cassia twig, 20g of radix paeoniae alba, 20g of semen cuscutae, 20g of eucommia ulmoides and 20g of salvia miltiorrhiza. The amounts of Atractylodis rhizoma, Poria, radix Angelicae sinensis, and radix astragali were all reduced compared to example 2. The preparation method is the same as that of example 2.
The following are clinical data
From 1 month in 2020 to 12 months in 2021, the inventor applies the skin scraping medicinal oil prepared by the invention to skin scraping treatment of 160 cases of chloasma patients in women and young health care hospitals in Liuzhou city, and the skin scraping medicinal oil has a better effect, and the report is as follows.
1. Clinical data
1.1, diagnostic criteria: chinese Association of Chinese and Western medicine for skin diseases pigmentary pathology group, clinical diagnosis and therapeutic effect standard of chloasma (2003 Ministry of revision)
The patches with clear boundaries are generally distributed symmetrically and have no inflammatory expression and scales. ② no obvious subjective symptom. ③ women have more hair, mainly after puberty. 4 the disease condition may be seasonal, usually severe in summer and mild in winter. 5 the removal of pigmentation caused by other diseases (such as naevus bruguinus, Rieh melanosis-grade pigmented actinic lichen planus, etc.).
1.3, clinical data: 160 patients were selected for treatment and observation, and the 160 patients were all selected from gynecologic clinic patients in Liuzhou city women-young health care institute in 1-2021 in 2020. The 160 cases are patients with chloasma, and are all screened strictly according to the standard.
2. The treatment method comprises the following steps:
2.1, encourages the patient to see the disease, increases the confidence of the patient in overcoming the disease, "eat, sleep, be happy", forms a good living habit, has dinner on time, has sufficient sleep, does not stay up all night, is relaxed, cooperates with the treatment.
2.2 the scraping medicinal oil is matched with the scraping treatment;
2.3 randomized into three groups of 40 people each
Test group one: the skin scraping medicinal oil prepared in example 2 was used.
Comparison group one: the skin scraping medicinal oil prepared in comparative example 1 was used.
Comparative group two: the skin scraping medicinal oil prepared in comparative example 2 was used.
And a third comparison group: tea oil is used as the scraping medicinal oil.
The scraping medicinal oil is used for scraping chloasma patients by matching with back, face and limbs, 2 times per week, 8 times as a treatment course, and two treatment courses are used.
3. The therapeutic effect judgment standard is as follows:
the basic cure is that firstly, the area of the visual color spot is faded by naked eyes to be more than 90 percent, and the color basically disappears;
the effect is shown that the area of the color spot is faded by naked eyes to be more than 60 percent, and the color is obviously lightened;
the improvement is that the area of the color spot is faded by more than 30 percent when the color is seen by naked eyes, and the color becomes light;
the color fading of the area of the visual color spot is less than 30 percent, and the color change is not obvious.
4. As a result: the results of treatment for four groups of patients after two treatment sessions are shown in table 1 below.
TABLE 1
The number of people who are basically cured Number of effective people Number of people who improve Number of invalid persons Effective rate (%) Recovery rate (%)
Test set one 18 15 6 1 97.5 45.0
Comparison group one 10 15 12 3 92.5 25.0
Comparison group two 13 14 11 2 95 32.5
Comparative group III 8 13 14 5 85 20.0
As can be seen from table 1, the effective rate of the traditional Chinese medicine composition of example 2 of the present invention can reach 95.8% by matching with corresponding acupoint scraping therapy. The traditional Chinese medicine formula in the comparative example group 1 lacks astragalus, cassia twig and eucommia bark, the effective rate is not obviously reduced, but the cure rate is greatly reduced. In the formula of the comparative example 2, the amount of the bighead atractylodes rhizome, the tuckahoe, the angelica and the astragalus is reduced, and the effective rate and the cure rate are also reduced. The traditional Chinese medicine has reasonable formula, has better treatment effect on chloasma patients, and obtains better clinical treatment effect by combining the scraping effect.
The above description is intended to describe in detail the preferred embodiments of the present invention, but the embodiments are not intended to limit the scope of the claims of the present invention, and all equivalent changes and modifications made within the technical spirit of the present invention should fall within the scope of the claims of the present invention.

Claims (5)

1. The effective components of the scraping medicinal oil comprise extracts of traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials are characterized by comprising the following raw materials in parts by weight: 25-35 parts of bighead atractylodes rhizome, 25-35 parts of poria cocos, 25-35 parts of Chinese angelica, 25-35 parts of astragalus membranaceus, 18-22 parts of ligusticum wallichii, 25-35 parts of radix rehmanniae recen, 8-12 parts of cassia twig, 18-22 parts of radix paeoniae alba, 18-22 parts of semen cuscutae, 18-22 parts of eucommia ulmoides, 18-22 parts of salvia miltiorrhiza and 18-22 parts of liquorice.
2. The method for preparing a scraping medicinal oil according to claim 1, which comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials in parts by weight;
(2) pulverizing the Chinese medicinal materials into powder to obtain Chinese medicinal powder;
(3) soaking the Chinese medicinal powder in oleum Camelliae for extraction;
(4) filtering and removing filter residues to obtain the scraping medical oil.
3. The method of claim 2, wherein: the traditional Chinese medicine powder is powder which is sieved by a sieve of 80-120 meshes.
4. The method of claim 2, wherein: in the step (3), the mass-to-volume ratio of the traditional Chinese medicine powder to the tea oil is 450-550 g: 4L of the reaction solution.
5. The method of claim 2, wherein: in the step (3), the soaking and extracting time is more than 12 h.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101518614A (en) * 2009-04-03 2009-09-02 杜继珍 Chinese patent medicine for treating chloasma
CN105687359A (en) * 2016-04-06 2016-06-22 王春霞 Composition for treating chloasma and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101518614A (en) * 2009-04-03 2009-09-02 杜继珍 Chinese patent medicine for treating chloasma
CN105687359A (en) * 2016-04-06 2016-06-22 王春霞 Composition for treating chloasma and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
彭先荣: "当归芍药散在妇科病中的运用", vol. 25, no. 11, pages 842 - 843 *
郝芬兰;: "自拟消斑养颜汤治疗黄褐斑114例疗效观察", vol. 28, no. 09, pages 91 - 92 *

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