CN115047194B - Fluorescent quantitative detection reagent card - Google Patents
Fluorescent quantitative detection reagent card Download PDFInfo
- Publication number
- CN115047194B CN115047194B CN202210659816.XA CN202210659816A CN115047194B CN 115047194 B CN115047194 B CN 115047194B CN 202210659816 A CN202210659816 A CN 202210659816A CN 115047194 B CN115047194 B CN 115047194B
- Authority
- CN
- China
- Prior art keywords
- pad
- shell
- air
- loading
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
Abstract
The utility model relates to a detect reagent card field specifically discloses a fluorescence ration detect reagent card, and it includes shell and detection module, detection module includes the bottom plate and sets gradually the loading pad on the bottom plate, combines pad, detection pad and inhales the sample pad, the shell corresponds the loading hole has been seted up to the position of loading pad, the shell corresponds the observation hole has been seted up to the position of combining pad, in the shell loading pad keep away from the one end that inhales the sample pad is equipped with the cover and locates the windbox of loading pad head end, be equipped with in the shell be used for to supply air in the windbox supply air mechanism. The method has the effects of high sampling liquid chromatography speed and high detection efficiency, and is suitable for instant screening of high-traffic areas.
Description
Technical Field
The application relates to the field of detection reagent cards, in particular to a fluorescent quantitative detection reagent card.
Background
The novel coronavirus IgM antibody detection kit generally has the following components according to the action principle: colloidal gold method, fluorescence immunochromatography, enzyme-linked immunosorbent assay, chemiluminescence method, etc. The principle of the fluorescent immunochromatography is based on a dry fluorescent labeling technology and an immunochromatography technology, a sample is dripped on a sample pad, and the sample moves forwards along a detection card under the capillary action. The novel coronavirus (SARS-CoV-2) antigen in the sample is combined with the labeled novel coronavirus (SARS-CoV-2) nucleocapsid protein monoclonal antibody to form an antigen-antibody complex. This complex migrates upward on the membrane by capillary effect until it is captured at the detection line (T-line) by the pre-coated novel coronavirus (SARS-CoV-2) nucleocapsid protein monoclonal antibody. As a quality control, the fluorescent immunoassay recognizes that the C-line signal indicates that an appropriate volume of sample has been added and that membrane chromatography has occurred.
The Chinese patent with publication number of CN206804667U in the related art proposes a multi-index time-resolved fluorescence immunochromatography kit for rapid quantitative detection of renal failure, which comprises a detection card, wherein the detection card comprises a sample loading pad, a combination pad, a detection pad with a detection line T and a quality control line C, a sample absorbing pad and a bottom plate.
With respect to the related art in the above, the inventors consider that there are the following drawbacks: after the sampling liquid is dripped into the sample adding hole of the reagent card, the sampling liquid permeates into the binding pad containing the detection antigen by virtue of capillary action in the sample adding pad and then permeates into the detection pad, even if the sample sucking pad is arranged at the other end of the reagent card so as to promote the chromatographic speed of the sampling liquid in the binding pad and the detection pad, 10-15 minutes still need to be consumed in the actual detection, the detection efficiency is low, and the detection device is not suitable for timely sampling detection in some areas with large human flow; in the process, the bonding pad and the sampling pad are exposed in the air, so that the detection result is easily affected due to secondary pollution.
Disclosure of Invention
In order to solve the problem that the detection rate is low because the reagent card needs to stand for a long time in self-test use, the application provides a fluorescent quantitative detection reagent card.
The application provides a fluorescence quantitative determination reagent card adopts following technical scheme:
the utility model provides a fluorescence ration detect reagent card, includes shell and detection module, detection module includes the bottom plate and sets gradually the loading pad on the bottom plate, combines the pad, detects the pad and inhale the sample pad, the shell corresponds the loading hole has been seted up to the position that the loading was filled up, the shell corresponds the observation hole has been seted up to the position that the combination was filled up, in the shell loading pad keep away from the one end that inhales the sample pad is equipped with the cover and locates the windbox of loading pad head end, be equipped with in the shell be used for to supply air in the windbox supply air mechanism.
Through adopting above-mentioned technical scheme, after dropping into the sampling pad with the sampling liquid of more number of drops in the loading hole, supply fresh air in the fan feed mechanism to the fan housing, this air forms the air current and is filled up to inhaling the sample pad circulation by the loading in the shell, can make the sampling liquid sample pad, combine pad and detect to fill up in the chromatography more rapidly, improved detection efficiency to can reduce the detection time of this application to a certain extent. Particularly in high-traffic areas such as airports, passenger stations, railway stations and the like needing landing detection, the device can be used for instant screening of passenger flows, is quick in detection timeliness, is small in passenger flow dead time, and can effectively and timely warn so as to prevent infection from further spreading after passenger flow is scattered.
Optionally, an air-slowing block is arranged at the air inlet of the air sleeve, and a plurality of air holes penetrate through the air-slowing block.
Through adopting above-mentioned technical scheme, the setting of slow wind piece can make the air current that gets into from the fan housing inlet milder, smooth and easy to the air current that is close to fan housing inlet department is too big, blows off the sampling liquid easily, has ensured the effective reaction duration of sampling liquid and combination pad and sampling pad in the material as far as possible.
Optionally, the air supply mechanism includes one end with the inflator of fan housing intercommunication, the inflator block in the shell, sealed slip is provided with the piston in the inflator, the rigid coupling has one end to extend to on the piston the outside push rod of shell.
Through adopting above-mentioned technical scheme, behind the handheld shell, the pull push rod can drive piston reciprocating motion in the inflator, and then can carry out continuous air feed to the fan housing to the speed of push rod is controllable, can make the air current velocity of flow of fan housing output controllable.
Optionally, a first sealing plate is fixedly connected to one end of the push rod, which is positioned outside the shell;
when the push rod pushes the piston to be closest to the loading pad, the first sealing plate completely seals the loading hole.
By adopting the technical scheme, when the push rod is pushed, the first sealing plate can be driven to slide on the shell, and as the airflow in the air sleeve blows the sample liquid detection module to perform chromatography, a certain probability exists that more sample liquid adsorbed at the sample loading pad is blown out from the sample loading hole, so that pollution is caused; at the moment, the first sealing plate can seal the sample loading hole when sliding along with the push rod, so that the phenomenon can be effectively avoided.
Optionally, the air supply mechanism includes with the air pocket of fan housing intercommunication, be provided with in the air pocket and be used for driving the air pocket inflation reset structure, be equipped with on the shell and be used for being convenient for extrude the extrusion structure of air pocket.
Through adopting above-mentioned technical scheme, after dripping the appearance and accomplishing, push away the structure through the squeeze and push down the air pocket for in the air pocket stores the air output to the gas pocket, after stopping pressing down the air pocket, reset structure further orders about by the expansion of the air pocket of flat and resumes to the former shape, thereby can last the air supply in the fan housing, with the chromatographic rate of accelerating sampling liquid in detection module.
Optionally, the return structure includes a return spring disposed along a direction in which the air bag contracts.
Through adopting above-mentioned technical scheme, after the air pocket is compressed, reset spring is compressed and is produced deformation, and after stopping external force and pressing, reset spring's deformation force drives the air pocket inflation reset to continue the suction air, in order to do benefit to the air feed in the gas pocket next time.
Optionally, the extruding structure includes a chute that is provided on the housing and is arranged along the length direction of the housing, a pressing plate that is positioned at one side of the air bag far away from the sample loading pad is provided in the housing, one end of the pressing plate penetrates through the chute and extends to the outside of the housing, and a second sealing plate is fixedly connected at the end;
when the pressing plate slides to be closest to the loading pad, the second sealing plate completely seals the loading hole.
Through adopting above-mentioned technical scheme, at the in-process through clamp plate extrusion air pocket, the second shrouding moves together along with the clamp plate to carry out the shutoff to the loading hole, when can effectively avoid the fan housing air feed too much, the sampling liquid in the loading pad is blown out and causes the pollution.
Optionally, the housing is covered with a transparent film at the observation hole.
Through adopting above-mentioned technical scheme, the setting of transparent film can carry out effective isolation to the detection pad of observation hole department, protection to prevent this application and unseal the back detection pad and place in the air for a long time and take place the pollution.
Optionally, a plurality of guard plates are fixedly connected in the shell, and the guard plates and the shell enclose to form a closed cavity for accommodating the detection module after the shell is closed.
Through adopting above-mentioned technical scheme, a plurality of backplate and the airtight chamber that the shell inner wall encloses the synthesis, can effectively ensure that the air current of output in the fan housing can flood in proper order in loading pad, combination pad and detection pad, promote the chromatographic rate of sampling liquid as high-efficient as possible.
Optionally, a plurality of fins are fixedly connected to the side walls, close to each other, of the two guard plates along the length direction of the shell at intervals, and the fins are obliquely arranged along the length direction of the shell.
By adopting the technical scheme, when the air flow output by the air sleeve circulates in the closed cavity, the air flows can be guided by the arrangement of the plurality of wing plates, so that the air flows can be gathered on one hand, and a better blowing effect on the sampling liquid is ensured; on the other hand, the two wing plates which are oppositely arranged reduce the sectional area of the air flow when the air flows through, and can play a role in accelerating the air flow.
In summary, the present application includes at least one of the following beneficial technical effects:
1. after more drop number's sampling liquid drops into the sample pad from the loading hole, supply fresh air in the fan feed mechanism to the fan housing, this air forms the air current and fills up to inhaling the sample pad circulation by the loading in the shell, can make the sampling liquid sample pad, combine pad and detect to fill up in the chromatography more rapidly, improved detection efficiency to can reduce the detection time of this application to a certain extent. Particularly in high-traffic areas such as airports, passenger stations, railway stations and the like needing landing detection, the method can be used for timely screening of passenger flows, is quick in detection timeliness, is small in passenger flow dead time, can effectively and timely warn, and is free from further spreading after passenger flow is scattered;
2. in the process of supplying air into the air sleeve, the first sealing plate and the second sealing plate can dynamically seal the sample loading holes, so that the phenomenon that sampling liquid in the sample loading pad is blown out to cause pollution when the air sleeve is excessively supplied with air is effectively avoided;
3. when the air flow output by the air sleeve circulates in the closed cavity, the air flows can be guided by the arrangement of the plurality of wing plates, so that on one hand, the air flows can be gathered, and a good blowing effect on the sampling liquid is ensured; on the other hand, the two wing plates which are oppositely arranged reduce the sectional area of the air flow when the air flows through, and can play a role in accelerating the air flow.
Drawings
Fig. 1 is a schematic overall structure of embodiment 1 of the present application.
Fig. 2 is a schematic structural view of a detection module of embodiment 1 of the present application.
Fig. 3 is a schematic cross-sectional structure of application example 1.
Fig. 4 is a schematic cross-sectional structure of application example 2.
Reference numerals illustrate: 1. a housing; 11. a sample loading hole; 12. an observation hole; 13. a transparent film;
20. a bottom plate; 21. a sample loading pad; 22. a bonding pad; 23. a detection pad; 24. a sample absorbing pad;
3. a wind sleeve;
4. a wind-slowing block;
51. an air cylinder; 52. a piston; 53. a push rod; 54. a first sealing plate;
61. an air bag; 62. a return spring; 63. a chute; 64. a pressing plate; 65. a second sealing plate; 66. a limiting plate;
71. a guard board; 72. a closed cavity; 73. an air outlet hole; 74. a wing panel.
Detailed Description
The present application is described in further detail below in conjunction with figures 1-4.
Example 1:
the embodiment of the application discloses a fluorescent quantitative detection reagent card. Referring to fig. 1 and 2, the fluorescent quantitative detection reagent card comprises a housing 1 and a detection module, wherein the housing 1 is formed by buckling a surface shell and a bottom shell, the detection module comprises a bottom plate 20, and a sample loading pad 21, a bonding pad 22, a detection pad 23 and a sample absorbing pad 24 which are sequentially arranged on the bottom plate 20, a sample loading hole 11 is formed in a position of the housing 1 corresponding to the sample loading pad 21, and an observation hole 12 is formed in a position of the housing 1 corresponding to the bonding pad 22. The one end that is kept away from in the sample loading pad 21 and absorbs sample pad 24 in shell 1 is equipped with the cover and locates the windward off cover 3 of sample loading pad 21 head end, and the air intake department of windward off cover 3 is provided with and delays wind piece 4, and it is in windward off cover 3 to slow wind piece 4 to pack, and it has a plurality of bleeder vents to run through in the slow wind piece 4, and during the concrete setting, slow wind piece 4 can be made for sponge, activated carbon layer, filter pulp etc. can play slow wind effect, can play again and carry out filterable effect to the air, is equipped with the air feed mechanism that is used for supplying air to in the windward off cover 3 in the shell 1.
After such setting, when carrying out quick self-checking, the person of being examined can drip into in the sample pad 21 with the sampling liquid of more number of drops from loading hole 11, supplies fresh air in the windband 3 through the air feed mechanism, and the setting of slow wind piece 4 can make the air current that gets into from windband 3 air intake milder, smooth and easy. The air flow circulates from the sample loading pad 21 to the sample absorbing pad 24 in the shell 1, so that the sample liquid can be rapidly analyzed in the sample loading pad 21, the combining pad 22 and the detecting pad 23, the detecting efficiency is improved, and the detecting time of the application can be shortened to a certain extent. Particularly in high-traffic areas such as airports, passenger stations, railway stations and the like needing landing detection, the device can be used for timely screening passenger flows, is quick in detection timeliness, is small in passenger flow dead time, can effectively and timely warn, and is used for preventing infection from further spreading after passenger flow is scattered.
Considering that the detection reagent card of the present application is a disposable product, and considering the processing cost and the assembly portability, referring to fig. 3, the air supply mechanism is configured to include an air cylinder 51 with one end communicated with the air sleeve 3, the air cylinder 51 is embedded in the housing 1 and is arranged along the length direction of the housing 1, a piston 52 is arranged in the air cylinder 51 in a sealing sliding manner, and a push rod 53 with one end extending to the outside of the housing 1 is fixedly connected to the piston 52; specifically designed, two baffles are integrally formed on the bottom shell of the shell 1, two ends of the length direction of the inflator 51 are clamped between the two baffles, a notch for inserting the push rod 53 is formed in the baffle which is away from the sample loading pad 21, and a hole for the push rod 53 to generate is reserved at the end part of the shell 1. The push rod 53 is located the outside one end rigid coupling of shell 1 and has first shrouding 54, and first shrouding 54 and inflator 51 overall structure are C, and when the push rod 53 promotes the piston 52 and is closest to the loading pad 21, first shrouding 54 shutoff loading hole 11 completely.
In this way, during the assembly of the present application, the piston 52 and the push rod 53 are assembled with the air cylinder 51, then the assembled air cylinder 51 is clamped between the two baffles on the bottom shell of the housing 1, and then the face shell of the housing 1 is covered, and at this time, the first sealing plate 54 is attached to the surface of the housing 1.
When the air blower is used, after the shell 1 is held by hand, the push rod 53 can be pulled to drive the piston 52 to reciprocate in the air cylinder 51, so that continuous air supply can be carried out on the air sleeve 3, the speed of pushing and pulling the push rod 53 can be controlled, and the flow rate of air flow output by the air sleeve 3 can be controlled; meanwhile, when the push rod 53 is pushed, the first sealing plate 54 can be driven to slide on the shell 1, so that even if more sampling liquid adsorbed at the sampling pad 21 is blown out from the sampling hole 11 by air flow, the first sealing plate 54 can also seal the sampling hole 11, and secondary pollution is effectively avoided.
Also in order to reduce secondary pollution during use of the present application, referring to fig. 3, the housing 1 is covered with a transparent film 13 at the observed hole 12. The transparent film 13 can effectively isolate and protect the detection pad 23 at the observation hole 12, so that the detection pad 23 is prevented from being polluted in the air for a long time after unsealing.
Moreover, in actual setting, the width of the bottom plate 20 can not reach the width of the casing 1, that is, the air flow output by the air sleeve 3 is dissipated in the inner cavity of the casing 1 with high probability, so that the promotion effect on the chromatographic speed of the sampling liquid in the detection module is weak, especially in the detection pad 23 far away from the sample loading pad 21, and the effect of improving the detection speed is less obvious.
In view of this, referring to fig. 3, a plurality of guard plates 71 surrounding the periphery of the bottom plate 20 are fixedly connected in the housing 1, and the guard plates 71 are integrally formed on the bottom shell of the housing 1, after the housing 1 is closed, the guard plates 71 and the housing 1 enclose a closed cavity 72 for accommodating the detection module, and an air outlet hole 73 for communicating with the closed cavity 72 is reserved at one end of the housing 1 far away from the sample loading hole 11; the side walls of the two guard plates 71 along the length direction of the shell 1, which are close to each other, are fixedly connected with a plurality of fins 74 at intervals, the fins 74 on the two guard plates 71 are arranged in a one-to-one correspondence manner, and the fins 74 are obliquely arranged along the length direction of the shell 1.
Therefore, the air flow output by the air sleeve 3 enters the closed cavity 72 formed by the plurality of guard plates 71 and the inner wall of the shell 1, so that the air flow output by the air sleeve 3 can be effectively ensured to be sequentially filled in the sample loading pad 21, the bonding pad 22 and the detection pad 23, and finally discharged from the air outlet holes 73, and the chromatographic speed of the sampling liquid can be promoted as efficiently as possible; in the process of circulating the air flow in the closed cavity 72, the air flows can be guided by the arrangement of the plurality of wing plates, so that on one hand, the air flows can be gathered, and a good blowing effect on the sampling liquid can be ensured; on the other hand, the two wing plates which are oppositely arranged reduce the sectional area of the air flow when passing through the two wing plates, form a Venturi effect, play a role in accelerating the air flow, and also promote the chromatographic speed of the air flow in the detection module after wrapping the sampling liquid, thereby improving the detection speed.
The implementation principle of the fluorescent quantitative detection reagent card in the embodiment of the application is as follows: when carrying out quick self-checking, the person of being examined can drop into the sample pad 21 with the sampling liquid of more number of drops from loading hole 11 after, and pull push rod 53 can drive piston 52 reciprocating motion in inflator 51, and then can carry out continuous air feed to fan housing 3, and the setting of slow fan block 4 can make the air current that gets into from fan housing 3 air intake milder, smooth and easy. The air flow circulates from the sample loading pad 21 to the sample absorbing pad 24 in the shell 1, so that the sample liquid can be rapidly analyzed in the sample loading pad 21, the combining pad 22 and the detecting pad 23, the detecting efficiency is improved, and the detecting time of the application can be shortened to a certain extent. Particularly in high-traffic areas such as airports, passenger stations, railway stations and the like needing landing detection, the device can be used for timely screening passenger flows, is quick in detection timeliness, is small in passenger flow dead time, can effectively and timely warn, and is used for preventing infection from further spreading after passenger flow is scattered.
Example 2:
the embodiment of the application discloses a fluorescent quantitative detection reagent card. Referring to fig. 4, the difference from embodiment 1 is that: the air supply mechanism comprises an air bag 61 communicated with the air sleeve 3, a reset structure for driving the air bag 61 to expand and reset is arranged in the air bag 61, and the reset structure comprises a reset spring 62 which is arranged in the air bag 61 and is arranged along the contraction direction of the air bag 61; when the air bag 61 is specifically arranged, the air bag 61 is cylindrical, two limiting plates 66 which are arranged in parallel are fixedly connected to the bottom shell of the shell 1, and the limiting plates 66 are axially arranged along the air bag 61. The shell 1 is provided with a squeezing structure for conveniently squeezing the air bag 61, the squeezing structure comprises a chute 63 which is arranged on the shell 1 and is arranged along the length direction of the shell 1, a pressing plate 64 which is positioned at one side of the air bag 61 far away from the sample loading pad 21 is arranged in the shell 1, one end of the pressing plate 64 penetrates through the chute 63 and extends to the outside of the shell 1, and a second sealing plate 65 is fixedly connected at the end part; when the platen 64 slides closest to the loading pad 21, the second closing plate 65 completely closes the loading hole 11.
Accordingly, after sample dripping is completed, the pressing plate 64 is pushed to press the air bag 61, so that air stored in the air bag 61 is output to the air sleeve 3, after the air bag 61 is stopped being pressed, the deformation force of the reset spring 62 drives the compressed air bag 61 to expand and restore to the original shape, and accordingly, air can be continuously supplied into the air sleeve 3 by repeatedly pushing the pressing plate 64, so that the chromatography speed of the sampling liquid in the detection module is increased. In this process, the second sealing plate 65 that is also provided can also effectively avoid the phenomenon that the sample liquid in the sample loading pad 21 is blown out to cause pollution when the air supply of the air jacket 3 is excessive.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.
Claims (2)
1. The utility model provides a fluorescence ration detect reagent card, includes shell (1) and detection module, detection module includes bottom plate (20) and sets gradually loading pad (21), combination pad (22), detection pad (23) and the sample absorbing pad (24) on bottom plate (20), shell (1) is corresponding loading hole (11) have been seted up in the position of loading pad (21), shell (1) is corresponding observation hole (12) have been seted up in the position of combination pad (22), its characterized in that: a wind sleeve (3) sleeved at the head end of the sample loading pad (21) is arranged at one end, far away from the sample absorbing pad (24), of the sample loading pad (21) in the shell (1), and a wind supply mechanism for supplying wind into the wind sleeve (3) is arranged in the shell (1);
an air slowing block (4) is arranged at the air inlet of the air sleeve (3), and a plurality of air holes penetrate through the air slowing block (4); the air-retarding block (4) is made of any one of sponge, active carbon layer and filter cotton;
the air supply mechanism comprises an air cylinder (51) with one end communicated with the air sleeve (3), the air cylinder (51) is embedded in the shell (1), a piston (52) is arranged in the air cylinder (51) in a sealing sliding manner, and a push rod (53) with one end extending to the outside of the shell (1) is fixedly connected to the piston (52); one end of the push rod (53) positioned outside the shell (1) is fixedly connected with a first sealing plate (54);
when the pushing rod (53) pushes the piston (52) to be closest to the loading pad (21), the first sealing plate (54) completely seals the loading hole (11);
a plurality of guard plates (71) are fixedly connected in the shell (1) and are arranged around the periphery of the bottom plate (20), and after the shell (1) is closed, the guard plates (71) and the shell (1) form a closed cavity (72) for accommodating the detection module;
a plurality of fins (74) are fixedly connected to the side walls, close to each other, of the two guard plates (71) in the length direction of the shell (1) at intervals, and the fins (74) are obliquely arranged in the length direction of the shell (1).
2. The fluorescent quantitative determination reagent card of claim 1, wherein: the housing (1) is covered with a transparent film (13) at the observation hole (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210659816.XA CN115047194B (en) | 2022-06-13 | 2022-06-13 | Fluorescent quantitative detection reagent card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210659816.XA CN115047194B (en) | 2022-06-13 | 2022-06-13 | Fluorescent quantitative detection reagent card |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115047194A CN115047194A (en) | 2022-09-13 |
| CN115047194B true CN115047194B (en) | 2023-06-30 |
Family
ID=83160788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210659816.XA Active CN115047194B (en) | 2022-06-13 | 2022-06-13 | Fluorescent quantitative detection reagent card |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115047194B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN207791640U (en) * | 2018-02-02 | 2018-08-31 | 宋树玲 | A kind of dept. of dermatology's sampling storage apparatus |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0421352D0 (en) * | 2004-09-24 | 2004-10-27 | City Tech | Sampling and analysis system and method |
| CN206214539U (en) * | 2016-08-24 | 2017-06-06 | 延安大学咸阳医院 | A kind of Medical oxygen bag pressue device |
| CN209356408U (en) * | 2018-11-21 | 2019-09-06 | 山东爱维德生物科技有限公司 | A kind of kit with time-resolved fluoroimmunoassay chromatography detection Ferritin Levels |
| US11730458B2 (en) * | 2019-02-14 | 2023-08-22 | Marshall Venture Partners LLC | Systems and methods for fluid sample collection and testing |
| CN210243507U (en) * | 2019-07-15 | 2020-04-03 | 呼和浩特职业学院 | Lateral flow sheet for detecting antibiotic residues |
| CN110275029A (en) * | 2019-07-30 | 2019-09-24 | 南通伊仕生物技术股份有限公司 | A kind of human chorionic gonadotrophin half-quantitative detection test paper, reagent cup and its preparation method and application |
| CN213337020U (en) * | 2020-10-13 | 2021-06-01 | 哈尔滨市农产品质量安全检验检测中心 | Lateral flow sheet for detecting mycotoxin |
-
2022
- 2022-06-13 CN CN202210659816.XA patent/CN115047194B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN207791640U (en) * | 2018-02-02 | 2018-08-31 | 宋树玲 | A kind of dept. of dermatology's sampling storage apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115047194A (en) | 2022-09-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6190822B2 (en) | Microfluidic reactor system | |
| US9140694B2 (en) | Assay system | |
| CN107238697B (en) | A method of it collects and detects sample | |
| CN107036847A (en) | A kind of applicator | |
| JP2015510111A5 (en) | ||
| ES2507092T3 (en) | Fluid test sensor that has vents to direct fluid flow | |
| CN115047194B (en) | Fluorescent quantitative detection reagent card | |
| WO2006046716A1 (en) | Reaction vessel | |
| CN107036848A (en) | The device that a kind of sample is collected and detected | |
| WO2023035617A1 (en) | Fast testing structure integrating sampling and testing and application thereof | |
| CN111351940A (en) | Novel coronavirus IgG detection reagent, reagent card, kit and preparation method thereof | |
| JP2011095164A (en) | Analysis chip and method of using the same | |
| CN109765363A (en) | Chemiluminescence-immune chromatography test paper and its detection method | |
| CN212222935U (en) | Detection system and liquid drop generating device thereof | |
| CN112858273A (en) | Detection kit for intelligent hospital, adaptive detection device and detection method | |
| CN206847996U (en) | Sample is collected and the device of detection | |
| US20120149093A1 (en) | Method and Apparatus for Automating Chemical and Biological Assays | |
| CN205484359U (en) | Card formula colloidal gold antibody detection device | |
| CN215986100U (en) | High efficiency lipoprotein associated phospholipase A2 check out test set | |
| CN206847995U (en) | Applicator | |
| US11353451B2 (en) | PoC test system and method | |
| JP2011095157A (en) | Collection instrument and method for using the same | |
| CN110691651B (en) | Fluid operation cartridge and control mechanism | |
| CN206456710U (en) | A kind of instant HP immunoblotting kit | |
| CN209979646U (en) | Enzyme-linked immunoassay kit for detecting toxins in food |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |