CN1150032C - Concentrated granular medicine for treating baby diarrhea and its preparing process - Google Patents
Concentrated granular medicine for treating baby diarrhea and its preparing process Download PDFInfo
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- CN1150032C CN1150032C CNB011067144A CN01106714A CN1150032C CN 1150032 C CN1150032 C CN 1150032C CN B011067144 A CNB011067144 A CN B011067144A CN 01106714 A CN01106714 A CN 01106714A CN 1150032 C CN1150032 C CN 1150032C
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- treating baby
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract
The present invention relates to a concentrated granular medicine for treating baby diarrhea and a preparing technology thereof, which provides a medicine for specially curing infantile diarrhea. The medicament is made of ten medicines of various enzymes, bismuth subcarbonate, folic acid, etc. and adjuvant materials, and the technology of concentrated granules for curing infantile diarrhea is prepared. The preparing technology is roughly divided into a process flow of sugar syrup deployment, soft wood granulation, hot air drying, weighing, packing, etc. The concentrated granular medicine for treating baby diarrhea has the advantages of scientific and reasonable proportion of the patent medicine preparation components, obvious supplement function, low cost, scientific fabrication process, simple administration, short treatment period, high curative effect and specially good effect on infantile sprue.
Description
The present invention treats the infantile diarrhea concentrated granular and preparation technology belongs to diarrhoea medicine and the preparation technology thereof that special for treating infant abdominal distention, enteritis, intestinal function wadding unrest and dyspepsia cause, relates in particular to a kind of treatment infantile diarrhea novel medicament prescription concentrated granular and preparation technology thereof.
Present domestic pharmacy corporation is produced special for treating children diarrheal preparation seldom, and market sale treatment infantile diarrhea drug formulation is outmoded, mostly is tablet and water preparation, and consumption is indicated not concrete, and the child takes inconvenience, DeGrain.
The present invention treats the infantile diarrhea concentrated granular and preparation technology provides fill a prescription reasonable, the significant new medicament of each prescription complementary action to suffering from the diarrhoea child.Not only craft science is easy for preparation treatment infantile diarrhea concentrated granular, and the codes and standards of temperature when having emphasized among the preparation technology that strict control operation chamber humidity and medicament are dry, noted the code requirement of medicament pH value again, guaranteed the stability of plurality of enzymes composition vigor and other saline crystallization bodies, make fully medicine composition reasonable combination, partner treatment, reached that gastrointestinal is ruled together, treating both the principal and the secondary aspects of a disease at the same time, the efficacy of a drug rapidly, through sick institute, evident in efficacy, with low cost, have no side effect.Infantile diarrhea is cured in soluble starch, the egg protein that solidifies and casein catapepsis and conversion that children's's stomach and intestinal portion are accumulated rapidly, makes children's's gastrointestinal recover normal digestive function.
In order to realize the foregoing invention purpose, its treatment infantile diarrhea concentrated granular and preparation technology thereof are as described below:
1, treatment infantile diarrhea concentrated granular is made up of pancreatin, pepsin, amylase, bismuth subcarbonate, acetomenadione, folic acid, white cane sugar powder, syrup, starch and food coloring prescription.Treatment infantile diarrhea each prescription of concentrated granular effective prescription amount, effectively degree is as shown in the table:
| The medicine name | Pancreatin | Pepsin | Amylase | Bismuth subcarbonate | Acetomenadione | Folic acid | White sucrose | Syrup 50% | Starch | Food coloring | Add up to |
| Formula ratio (gram) | 1200 | 400 | 1200 | 3000 | 20 | 50 | 1000 | 2300 | 500 | 330 | 10000 |
| Content (%) | 12.0 | 4.0 | 12.0 | 30.0 | 0.2 | 0.5 | 10.0 | 23.0 | 5.0 | 3.3 | 100 |
2, the preparation technology of treatment infantile diarrhea concentrated granular is as described below:
(1) prescription is equipped with medicine respectively weighing get all the ready, it is standby that solid medicine is crossed 80 mesh sieves respectively.
(2) except that syrup, with each prescription element by effective prescription amount assort in oscillating granulator do mix 10 minutes evenly the back add quantitative syrup and make soft material.
(3) soft material is granulated with 18 eye mesh screens, and through heat-wind circulate drying below 45 ℃ to water content below 2%, being distributed into 12 gram pouches is patent medicine.
(4) live for stabilized enzyme, will notice that humidity is controlled in 65% between the chamber when making, temperature can not be above 45 ℃ when dry.
(5) in order to make folic acid keep stable, the soft material pH value must be grasped between 6.0-9.8 when making, and the changeable bismuth subcarbonate makes the soft material pH value obtain adjusting in case of necessity.
Treatment infantile diarrhea concentrated granular instructions of taking: one day three times, each 4 restrained warm boiled water with interior children's in 6 months; 6 months to 1 years old children's, one day three times, each 6 grams, warm boiled water; 1-2 year, one day three times, each 12 grams, warm boiled water; More than 3 years old, one day three times, each 24 grams, warm boiled water.
Diarrhoea is common disease in children; be to cause dyspepsia after improper owing to pediatric diet, the hungry full variable or edible unclean food that goes bad; make starch adhere to gastrointestinal; egg protein solidifies in gastrointestinal; casein stops to transform, and the stimulating intestinal function wadding is random, and enterokinesia is accelerated; moisture content and nutrition can not absorb, and it is external directly to discharge children's.Infant abdominal distention and stool are the primary disease main clinical manifestation as water.Pancreatin, amylase and pepsin in this medicine prescription have the facilitating digestion function, and wherein amylase can make the soluble starch catapepsis, and pepsin can make the egg protein catapepsis of solidifying, and pancreatin can make casein be converted into peptone rapidly and be absorbed.Folic acid is enriched blood, is fitted blood and anti-inflammation and sterilization function, and children's's sprue is had specially good effect.Bismuth subcarbonate has convergence and protective effect for forming the alkali formula carbonate of indefinite bismuth to the intestines and stomach mucosa, can make infant abdominal distention after the gastrointestinal function wadding disorderly recover normal rapidly.Acetomenadione can participate in the liver intravascular coagulation, can prevent after the inflammation of children's's the intestines and stomach hemorrhagely, and loose intestinal smooth muscle is arranged, removes spasm, promotes the effect of moisture absorption, thereby reach the antidiarrheal purpose.White sucrose, syrup and starch not only are this medicine binding, and can make medicine improvement bitterness, increase children's's preference.
Modern pharmacology proves; more than each medicine share; after children's is oral; medicine promptly directly enters each medicine of gastrointestinal organ pipe and has complementary functions; make to accumulate in the gastrointestinal with adherent food body to obtain digestion rapidly, the pathogenic bacteria in the mucus is killed rapidly, and mucosa obtains convergence, replenishes and protection; diarrhoea is stopped, and children's's gastrointestinal function and stool recover normal.
Treatment infantile diarrhea concentrated granular prescription is through long-term clinical application and update, select for use all medicines in syrup, to be mixed, its effective ingredient is concentrated one, form even bonded particulate, compatibility is reasonable, the oral back of children's complementary action is remarkable, can treat infantile diarrhea, particularly treat the infantile diarrhea disease that enteritis, intestinal function wadding unrest and dyspepsia cause, easy to use, effect is obvious, effective percentage reaches 100%, and cure rate reaches 95%, and this children's oral medication diarrhoea concentrated granular is with low cost, the curative effect height, have no side effect, children's's sprue is had specially good effect.
Claims (1)
1, treatment infantile diarrhea concentrated granular, it is characterized in that making: pancreatin 12.0% by following raw materials according, pepsin 4.0%, amylase 12.0%, bismuth subcarbonate 30.0%, acetomenadione 0.2%, folic acid 0.5%, white sucrose 10.0%, syrup 23.0%, starch 5.0%, food coloring 3.3%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011067144A CN1150032C (en) | 2001-01-15 | 2001-01-15 | Concentrated granular medicine for treating baby diarrhea and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011067144A CN1150032C (en) | 2001-01-15 | 2001-01-15 | Concentrated granular medicine for treating baby diarrhea and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1329923A CN1329923A (en) | 2002-01-09 |
| CN1150032C true CN1150032C (en) | 2004-05-19 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011067144A Expired - Fee Related CN1150032C (en) | 2001-01-15 | 2001-01-15 | Concentrated granular medicine for treating baby diarrhea and its preparing process |
Country Status (1)
| Country | Link |
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| CN (1) | CN1150032C (en) |
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| US6632429B1 (en) | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
| US20070053895A1 (en) | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
| US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
| US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
| US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
| US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
| US9320780B2 (en) | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
| ES2732453T3 (en) | 2008-07-01 | 2019-11-22 | Curemark Llc | Methods and compositions for the treatment of symptoms of neurological and mental health disorders |
| US10776453B2 (en) | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
| US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
| AU2010203709B2 (en) | 2009-01-06 | 2014-05-22 | Galenagen, Llc | Compositions and methods for the treatment or prevention of Staphylococcus Aureus infections and for the Eradication or reduction of Staphylococcus Aureus on surfaces |
| WO2010080835A1 (en) | 2009-01-06 | 2010-07-15 | Curemark Llc | Compositions and methods for the treatment or the prevention oral infections by e. coli |
| US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
| US9511125B2 (en) | 2009-10-21 | 2016-12-06 | Curemark Llc | Methods and compositions for the treatment of influenza |
| DK2701733T3 (en) | 2011-04-21 | 2019-05-27 | Curemark Llc | CONNECTIONS FOR TREATMENT OF NEUROPSYCIATRIC DISORDERS |
| US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
| CN109620809A (en) * | 2019-02-25 | 2019-04-16 | 李潇 | A kind of preparation method of Instant Gefitinib tablet medicament composition |
| US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
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2001
- 2001-01-15 CN CNB011067144A patent/CN1150032C/en not_active Expired - Fee Related
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