CN114867846A - 多靶向效应细胞和其用途 - Google Patents

多靶向效应细胞和其用途 Download PDF

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Publication number
CN114867846A
CN114867846A CN202080080349.4A CN202080080349A CN114867846A CN 114867846 A CN114867846 A CN 114867846A CN 202080080349 A CN202080080349 A CN 202080080349A CN 114867846 A CN114867846 A CN 114867846A
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cells
cell
derived
car
bcma
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Chinese (zh)
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B·瓦拉梅尔
R·比乔戴尔
J·古德里奇
T·T·李
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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CN202080080349.4A 2019-09-25 2020-09-25 多靶向效应细胞和其用途 Pending CN114867846A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962906046P 2019-09-25 2019-09-25
US62/906,046 2019-09-25
US201962944187P 2019-12-05 2019-12-05
US62/944,187 2019-12-05
PCT/US2020/052890 WO2021062281A2 (en) 2019-09-25 2020-09-25 Multi-targeting effector cells and use thereof

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CN114867846A true CN114867846A (zh) 2022-08-05

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US (1) US20220378831A1 (https=)
EP (1) EP4034638A4 (https=)
JP (2) JP2022548943A (https=)
KR (1) KR20220085779A (https=)
CN (1) CN114867846A (https=)
AU (1) AU2020353166A1 (https=)
BR (1) BR112022005602A2 (https=)
CA (1) CA3149585A1 (https=)
IL (1) IL291484A (https=)
MX (1) MX2022003414A (https=)
WO (1) WO2021062281A2 (https=)

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CN108368520A (zh) * 2015-11-04 2018-08-03 菲特治疗公司 多能细胞的基因组工程改造
WO2024099265A1 (zh) * 2022-11-07 2024-05-16 上海先博生物科技有限公司 工程化嵌合抗原受体免疫细胞及其应用
WO2025021201A1 (en) * 2023-07-26 2025-01-30 BRL Medicine Inc. Method and composition for treating diseases

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US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
WO2019164930A1 (en) * 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
EP4097220A4 (en) * 2020-01-30 2024-03-20 ImmunityBio, Inc. ELIMINATION OF BCMA-POSITIVE MALIGNANCIES BY CAR-EXPRESSING NK CELLS
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
JP2024522756A (ja) * 2021-06-18 2024-06-21 オーエヌケイ セラピューティクス リミテッド ダブルノックアウトナチュラルキラー細胞
US20240316102A1 (en) 2021-07-01 2024-09-26 Indapta Therapeutics, Inc. Engineered natural killer (nk) cells and related methods
GB202110363D0 (en) * 2021-07-19 2021-09-01 Celyad S A NKG2D CAR cells expressing IL-18 for adoptive cell therapy
CN117835993A (zh) * 2021-08-18 2024-04-05 菲特治疗公司 作为单一疗法以及与抗体组合的现成的iPSC衍生的CAR-NK细胞
AU2022371471A1 (en) * 2021-10-20 2024-05-02 Fate Therapeutics, Inc. Effector cells and use thereof for allogeneic adoptive cell therapies in solid tumors
KR20240102994A (ko) * 2021-11-08 2024-07-03 페이트 세러퓨틱스, 인코포레이티드 고형 종양의 유비쿼터스 표적화를 향상시키는 조작된 이펙터 세포 및 방법
US20250228943A1 (en) * 2022-04-08 2025-07-17 Fate Therapeutics, Inc. Cells having solid tumor targeting backbone and use thereof
US20250222029A1 (en) 2022-04-08 2025-07-10 Fate Therapeutics, Inc. Chimeric antigen receptor for tumor targeting
JP2025525439A (ja) 2022-06-30 2025-08-05 インダプタ セラピューティクス インコーポレイテッド 操作されたナチュラルキラー（ｎｋ）細胞と抗体療法との組み合わせおよび関連する方法
WO2024068617A1 (en) * 2022-09-26 2024-04-04 Institut Curie Myeloid cells expressing il-2 and uses thereof for quick anticancer therapy
WO2025109493A1 (en) * 2023-11-21 2025-05-30 National University Of Singapore Chimeric Receptors with Binding Capacity for Antibodies

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CN117721084A (zh) * 2017-10-12 2024-03-19 美商生物细胞基因治疗有限公司 靶向多种抗原的复合嵌合抗原受体（cCAR）及其组成和使用方法
JP2021505131A (ja) * 2017-12-08 2021-02-18 フェイト セラピューティクス，インコーポレイテッド 増強されたｉＰＳＣ由来のエフェクター細胞を用いた免疫療法

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US20130156770A1 (en) * 2011-11-15 2013-06-20 Boehringer Ingelheim International Gmbh Binding molecules for bcma and cd3
CN106661109A (zh) * 2014-04-30 2017-05-10 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 抗cd269(bcma)人源化抗体
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CN109641012A (zh) * 2016-06-07 2019-04-16 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 与bcma结合的嵌合抗原受体和car-t细胞
WO2019126748A1 (en) * 2017-12-22 2019-06-27 Fate Therapeutics, Inc. Enhanced immune effector cells and use thereof

Cited By (4)

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WO2021062281A2 (en) 2021-04-01
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JP2022548943A (ja) 2022-11-22
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