CN114848735A - Traditional Chinese medicine composition and preparation method thereof - Google Patents

Traditional Chinese medicine composition and preparation method thereof Download PDF

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Publication number
CN114848735A
CN114848735A CN202210446858.5A CN202210446858A CN114848735A CN 114848735 A CN114848735 A CN 114848735A CN 202210446858 A CN202210446858 A CN 202210446858A CN 114848735 A CN114848735 A CN 114848735A
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chinese medicine
traditional chinese
medicine composition
chinese medicinal
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张海龙
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Central International Intellectual Property Services Baotou Co ltd
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Central International Intellectual Property Services Baotou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

The invention discloses a traditional Chinese medicine composition for treating gastritis, which consists of effective components or pharmaceutically acceptable carriers, wherein the effective components mainly comprise desmodium, scutellaria, coptis, dandelion, trichosanthes kirilowii maxim, ginger processed pinellia and the like, and the traditional Chinese medicine composition is prepared into any pharmaceutically acceptable dosage form.

Description

Traditional Chinese medicine composition and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine composition, and more particularly relates to a traditional Chinese medicine composition for treating gastritis and a preparation method of the traditional Chinese medicine composition.
Background
Reflux gastritis belongs to the categories of epigastric pain, gastric upset, vomiting gall and the like in the traditional Chinese medicine. It is usually caused by emotional impairment, adverse flow of qi of liver and gallbladder and dysfunction of qi in the liver and gallbladder, manifested as epigastric pain, vomiting of bile and bitter taste in mouth, with the pathogenesis of adverse flow of gallbladder and internal factors of weakness of spleen and stomach, and the main pathological product is damp-heat.
Reflux gastritis is a special type of chronic gastritis in clinical use, and the cause of the reflux of bile into the stomach. Under normal conditions, the pyloric sphincter, the exit of the stomach, relaxes to allow chyme in the stomach to pass into the duodenum, and if the pyloric sphincter is "ajar", bile in the duodenum can flow back into the stomach causing chronic gastritis. Bile salt in bile can weaken the protection mechanism of gastric mucosa, so that acid originally secreted into gastric cavity can be reversely diffused into gastric mucosa to cause damage of gastric mucosa, the bile salt stimulates gastrin to be released at the antrum of the stomach, the gastrin can stimulate gastric acid secretion, further damage of gastric mucosa is caused, gastric mucositis is caused, and a plurality of gastritis symptoms can appear.
According to the traditional Chinese medicine, the syndrome of liver depression invading the stomach, the qi movement of the middle energizer is unfavorable, the stomach is in harmony with the descending, the spleen qi is unfavorable, and the transportation and transformation are failure. The treatment mainly takes the principle of regulating qi and preferably descending, and takes soothing the liver and harmonizing the stomach as the fundamental treatment method.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating reflux gastritis, which comprises the following components: herba lysimachiae, scutellaria baicalensis, coptis chinensis, dandelion, fructus trichosanthis, ginger processed pinellia ternate, pericarpium citri reticulatae, medicated leaven, elecampane, fructus aurantii and radix codonopsis pilosulae.
Another preferred Chinese medicinal composition for treating reflux gastritis comprises: herba Lysimachiae, radix Scutellariae, rhizoma Coptidis, herba Taraxaci, fructus Trichosanthis, rhizoma Pinelliae Preparada, pericarpium Citri Reticulatae, Massa Medicata Fermentata, radix aucklandiae, fructus Aurantii, and radix astragali.
Another preferred Chinese medicinal composition for treating reflux gastritis comprises: herba Lysimachiae, radix Scutellariae, rhizoma Coptidis, herba Taraxaci, fructus Trichosanthis, rhizoma Pinelliae Preparada, pericarpium Citri Reticulatae, Massa Medicata Fermentata, radix aucklandiae, fructus Aurantii, radix Codonopsis, radix Glycyrrhizae, and radix astragali.
Another preferred Chinese medicinal composition for treating reflux gastritis of the invention comprises: herba Lysimachiae, radix Scutellariae, rhizoma Coptidis, herba Taraxaci, fructus Trichosanthis, rhizoma Pinelliae Preparada, pericarpium Citri Reticulatae, Massa Medicata Fermentata, radix aucklandiae, fructus Aurantii, radix Codonopsis, radix Glycyrrhizae, Poria, and radix astragali.
The invention also discloses another preferred traditional Chinese medicine composition for treating reflux gastritis, which comprises the following raw materials in parts by weight:
5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of elecampane, 3-80 parts of fructus aurantii, 3-50 parts of codonopsis pilosula and 3-80 parts of honey-fried licorice root.
Preferably, the composition comprises 5-80 parts by weight of desmodium, 5-50 parts by weight of scutellaria baicalensis, 3-50 parts by weight of coptis chinensis, 3-50 parts by weight of dandelion, 3-50 parts by weight of fructus trichosanthis, 3-50 parts by weight of ginger processed pinellia, 3-50 parts by weight of dried orange peel, 3-80 parts by weight of medicated leaven, 3-80 parts by weight of elecampane, 3-80 parts by weight of fructus aurantii, 3-50 parts by weight of codonopsis pilosula, 5-30 parts by weight of poria cocos and 3-80 parts by weight of honey-fried licorice root.
Preferably, the invention provides another traditional Chinese medicine composition for treating reflux gastritis, which comprises the following raw materials in parts by weight: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of elecampane, 3-80 parts of fructus aurantii, 3-50 parts of astragalus membranaceus and 3-80 parts of honey-fried licorice root.
According to the pathogenesis analysis of the reflux gastritis, the treatment method is determined to harmonize the stomach, descend the adverse flow and regulate the flow of qi. The effective components of the traditional Chinese medicine composition are prepared from the traditional Chinese medicine components for harmonizing the stomach, lowering adverse qi and regulating qi. According to one technical scheme, the traditional Chinese medicine materials for preparing the traditional Chinese medicine composition comprise desmodium, scutellaria baicalensis, coptis chinensis, dandelion, fructus trichosanthis, ginger processed pinellia ternate, pericarpium citri reticulatae, medicated leaven, elecampane, fructus aurantii, codonopsis pilosula and roasted liquorice. Wherein the use amount of the components is as follows by weight: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of elecampane, 3-80 parts of fructus aurantii, 3-50 parts of codonopsis pilosula and 3-80 parts of honey-fried licorice root.
Another preferred technical scheme of the traditional Chinese medicine composition is that the traditional Chinese medicine raw materials for preparing the traditional Chinese medicine composition comprise desmodium, scutellaria baicalensis, coptis chinensis, dandelion, fructus trichosanthis, ginger processed pinellia ternate, pericarpium citri reticulatae, medicated leaven, elecampane, fructus aurantii, astragalus mongholicus and radix glycyrrhizae preparata. Wherein the use amount of the components is as follows by weight: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of elecampane, 3-80 parts of fructus aurantii, 3-50 parts of astragalus membranaceus and 3-80 parts of honey-fried licorice root.
In another technical preferred scheme, a medicine with the stomach qi regulating effect can be added into the traditional Chinese medicine raw materials of the effective components of the traditional Chinese medicine composition, and the stomach qi regulating medicine is one or more selected from clove, calyx kaki, immature bitter orange and the like. The adding amount of the raw materials is 3-50 parts by weight of clove, 3-50 parts by weight of calyx kaki and 3-50 parts by weight of immature bitter orange.
In another preferred technical scheme, a medicine with the effect of strengthening spleen deficiency and tiredness can be added into the traditional Chinese medicine raw materials for preparing the effective components of the traditional Chinese medicine composition. The medicine for enhancing the spleen deficiency and the fatigue is selected from radix pseudostellariae, Chinese yam and bighead atractylodes rhizome. One or more of them may be added. The dosage of the traditional Chinese medicine composition is 3-50 parts by weight of radix pseudostellariae, 3-50 parts by weight of Chinese yam and 3-50 parts by weight of bighead atractylodes rhizome.
According to another preferred technical scheme, the traditional Chinese medicine raw materials for preparing the effective components of the traditional Chinese medicine composition can also be used as digestant, and the digestant is selected from malt, endothelium corneum gigeriae galli and radix pseudostellariae. One or more of them may be added. The dosage of the ingredients is 5-30 parts of malt, 5-30 parts of chicken's gizzard-membrane and 3-30 parts of heterophylly falsestarwort root.
In another preferable technical scheme, the traditional Chinese medicine raw materials for preparing the effective components of the traditional Chinese medicine composition can be added with medicines for treating bitter taste in the mouth and damp-heat in liver and gallbladder, and the medicines for treating bitter taste in the mouth and damp-heat in liver and gallbladder are selected from oriental wormwood and are used in an amount of 5-30 parts by weight of oriental wormwood.
According to another preferable technical scheme, the laxative can be added into the traditional Chinese medicine raw materials for preparing the effective components of the traditional Chinese medicine composition, and the laxative is selected from 6-20 g of raw rhubarb and tuber fleeceflower root. One or more of them may be added. The dosage of the raw rhubarb and the raw fleece-flower root is 6 to 20 weight parts of raw rhubarb and 6 to 20 weight parts of raw fleece-flower root.
In another preferred technical scheme, a medicine for neutralizing gastric acid can be added into the traditional Chinese medicine raw materials for preparing the effective components of the traditional Chinese medicine composition, and the medicine for neutralizing gastric acid is selected from cuttlebone, and the dosage of the medicine is 5-30 parts by weight of the cuttlebone.
The invention relates to a traditional Chinese medicine compound preparation for treating reflux gastritis, which takes the following raw materials or water extracts of the following raw materials or water extracts as active ingredients, and the raw materials comprise the following components in parts by weight:
5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of costustoot, 3-80 parts of fructus aurantii, 3-50 parts of codonopsis pilosula and 3-80 parts of honey-fried licorice root.
The invention also aims to provide a preparation method of the traditional Chinese medicine composition for treating reflux gastritis.
The effective components contained in the medicine of the invention can be prepared by the following steps: drying the above Chinese medicinal materials, grinding into powder, and mixing to obtain effective components.
The active ingredients contained in the medicine can also be prepared by the following steps: decocting the above Chinese medicinal materials with water, and filtering to obtain effective components.
The active ingredients contained in the medicament of the invention are preferably prepared by the following steps: decocting the Chinese medicinal composition with water for three times, mixing filtrates, filtering, mixing the filtrate with the steamed aqueous solution, concentrating to relative density of 1.0-2.0 at 50C, refrigerating, filtering, and concentrating to obtain soft extract with relative density of 1.0-2.0 at 50C; mixing with above soft extract, drying under reduced pressure to obtain dry extract, and mixing.
The preparation process of the effective components contained in the medicament of the invention can also preferably be prepared by the following steps: decocting the traditional Chinese medicine material composition with water for three times, combining filtrates, filtering, combining the filtrate with the steamed aqueous solution, concentrating until the relative density is 1.0-2.0 measured at 50C, refrigerating, filtering, and concentrating to obtain thick paste, wherein the relative density is 1.0-2.0 measured at 50C; mixing with above soft extract, drying under reduced pressure to obtain dry extract, pulverizing dry extract into fine powder, mixing with above fine powder, adding appropriate amount of adjuvant, mixing, granulating, drying, sieving, grading, and making into capsule.
The effective components of the invention can be prepared into any pharmaceutical dosage forms with pharmaceutically acceptable auxiliary materials, and the dosage forms comprise oral preparations such as tablets, capsules, oral liquid, granules and the like, and intravenous injection preparations such as injection, powder injection, infusion solutions and the like. Oral formulations are preferred.
Reflux gastritis, as described herein, includes reflux esophagitis, and reflux gastritis.
The invention has the beneficial effects that: the invention adopts a novel traditional Chinese medicine composition, and the method comprises the following steps: (1) no side effect; (2) has good effect of treating the reflux gastritis, and main symptoms are eliminated after 30-90 days of treatment. No obvious inflammation and bile are seen in the gastroscope review; (3) the raw medicinal materials are low in price, and the treatment cost of a patient can be effectively reduced.
Detailed Description
The present invention is further illustrated by the following examples, which are not intended to limit the invention in any way. The reagents, methods and apparatus employed in the present invention are conventional in the art, unless otherwise specified.
Example 1
Li Shi patient, male, 65 years old, has a gastric cavity inflated for more than 2 months. Distending and stuffy feeling in the stomach, hunger before meal, belching, gastric upset, nausea, acid regurgitation and greasy tongue coating. Electronic gastroscopy prompting: reflux gastritis. B-mode ultrasound showed that the gallbladder wall was slightly rough. And (3) Western diagnosis: reflux gastritis;
prescription: 30g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 15g of dandelion, 15g of fructus trichosanthis, 15g of ginger processed pinellia tuber, 10g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 15g of codonopsis pilosula and 6g of honey-fried licorice root.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, 2 times a day. Order to have a light diet, harmonize emotion and work and ease. After continuous taking for 50 days, the main symptoms are basically eliminated, and the result of repeated examination by a gastroscope is as follows: no obvious inflammation and bile are seen in gastroscopy, and no regurgitation is seen at pyloric opening. B-mode ultrasound showed that the gallbladder wall was slightly rough and disappeared.
Example 2
Yellow certain, female, 56 years old. Before 1 month, patients have gastric cavity, and the curative effect is poor after taking the medicine for promoting gastric motility and protecting gastric mucosa, dry mouth, acid regurgitation, belch, nausea, emesis, gastric upset, abdominal pain and greasy tongue coating. The gastroscopy is performed: reflux gastritis. B-mode ultrasound showed that the gallbladder wall was slightly rough. And (3) Western diagnosis: reflux gastritis.
Prescription: 50g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 15g of dandelion, 15g of fructus trichosanthis, 15g of ginger processed pinellia tuber, 10g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 10g of astragalus mongholicus and 3g of honey-fried licorice root.
The preparation is decocted in water of 400ml per day, 200ml per time and twice a day, and is orally taken 15-30 min before meals. And order that the diet is light and harmonize the emotion. After continuous taking for 40 days, the main symptoms are basically eliminated. And (5) gastroscopy result: no obvious inflammation and bile are seen in gastroscopy, and no regurgitation is seen at pyloric opening.
Example 3
Liu Zhi, female, 60 years old, the patient has distending pain and discomfort in the upper abdomen, mild and severe symptoms, and has had recurrent attacks for 2 months. The administration of morpholine and drugs for the treatment of gastropathy is frequent. Poor appetite, belching, domination of qi and stagnation of qi movement. Gastroscopy: in the gastric mucus pool, a large amount of yellow-green bile is stored, the gastric mucosa is congested and red, and a small amount of bile flows back into the stomach. And (3) diagnosing gastric environment: reflux gastritis. B ultrasonic wave showed that the gallbladder wall was slightly rough.
Prescription: 10g of desmodium, 30g of scutellaria baicalensis, 20g of coptis chinensis, 30g of dandelion, 30g of fructus trichosanthis, 30g of ginger processed pinellia tuber, 30g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 20g of codonopsis pilosula, 6g of honey-fried licorice root, 10g of clove, 10g of calyx kaki and 10g of immature bitter orange.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, twice a day. Order to harmonize emotion by its light diet. The symptoms are eliminated after continuous taking for 30 days. And (5) gastroscopy result: no obvious inflammation and bile are seen in the gastroscope. B ultrasonic wave shows that the gallbladder wall is slightly rough and disappears.
Example 4
Lie, male, age 68. The distending pain of the stomach can be recurrent for 5 years, and aggravated for half a year. Patients often have epigastric distending pain, bitter taste in mouth, belching, yellowish complexion and excessive damp-heat in liver and gallbladder for 5 years. Gastroscopy shows: gastric mucosa is congested, mucous lake is yellow and turbid, and bile flows back at pyloric opening. Reflux gastritis was diagnosed. B-mode ultrasound showed that the gallbladder wall was slightly rough.
Prescription: 5g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 10g of dandelion, 10g of fructus trichosanthis, 10g of ginger processed pinellia tuber, 10g of dried orange peel, 30g of medicated leaven, 30g of costustoot, 50g of fructus aurantii, 30g of codonopsis pilosula, 30g of honey-fried licorice root and 20g of oriental wormwood.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, twice a day. Advocate it not to overwork, so it is happy and emotional, and regulate diet. The main symptoms are eliminated after continuous taking for 60 days.
And (5) gastroscopy result: no obvious inflammation and bile are seen in gastroscopy, and no bile reflux is seen at the pyloric opening. B ultrasonic wave shows that the gallbladder wall is slightly rough and disappears.
Example 5
Zhongji, women, age 52, chief complaints are gastric distention and acid regurgitation for more than half a year. The distention and fullness of the stomach, pungent and pungent food or aggravated after qi generation, frequent belching and poor appetite can be mentioned. Inspection of gastroscopy shows that congestion and edema of gastric mucosa are obvious, and a large amount of bile-containing reflux liquid can be seen; b-mode ultrasound showed that the gallbladder wall was slightly rough. Omeprazole, domperidone and other medicines have poor effects once taken. The western medicine diagnoses bile reflux gastritis.
Prescription: 20g of desmodium, 10g of scutellaria baicalensis, 6g of coptis chinensis, 10g of dandelion, 50g of fructus trichosanthis, 50g of ginger processed pinellia tuber, 50g of dried orange peel, 5g of medicated leaven, 5g of costustoot, 5g of fructus aurantii, 5g of codonopsis pilosula, 6g of honey-fried licorice root, 5g of malt, 5g of endothelium corneum gigeriae galli and 10g of radix pseudostellariae.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, twice a day. Advocate it not to overwork and to be happy. The main symptoms are eliminated after continuous taking for 60 days. And (5) gastroscopy result: bile reflux is not seen. B ultrasonic wave shows that the gallbladder wall is slightly rough and disappears.
Example 6
Whichever, female, 55 years old. The patient has distending pain in the stomach, bitter taste in the mouth and belching. The symptoms are aggravated in the last half of the year, and the stomach is noisy, weak and weak. Gastroscopy shows: gastric mucosa is congested, the mucous lake is yellow and turbid, and bile flows back at the pyloric opening. B-mode ultrasound showed that the gallbladder wall was slightly rough. The western medicine diagnoses bile reflux gastritis.
Prescription: 10g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 50g of dandelion, 50g of fructus trichosanthis, 15g of ginger processed pinellia tuber, 10g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 5g of astragalus mongholicus, 6g of honey-fried licorice root, 15g of radix pseudostellariae, 15g of yam, 10g of bighead atractylodes rhizome and 8g of American ginseng.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, twice a day. Advocate it not to be overstrained and to be happy. After continuous taking for 50 days, the main symptoms are eliminated.
And (5) gastroscopy result: no obvious inflammation and bile are seen in gastroscopy. B ultrasonic wave shows that the gallbladder wall is slightly rough and disappears.
Example 7
Male, 53 years old, in certain weeks. The patient has distending pain in the stomach, belching, gastric upset, asthenia and hypodynamia. Gastroscopy shows: gastric mucosa is congested, mucous lake is yellow and turbid, and bile flows back at pyloric opening. B-mode ultrasonography shows that the gallbladder wall is slightly rough. The western medicine diagnoses bile reflux gastritis.
Prescription: 10g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 50g of dandelion, 50g of fructus trichosanthis, 15g of ginger processed pinellia tuber, 10g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 10g of astragalus membranaceus, 6g of honey-fried licorice root, 15g of radix pseudostellariae, 15g of yam, 10g of bighead atractylodes rhizome and 8g of American ginseng.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, twice a day. After continuous taking for 50 days, the main symptoms are eliminated. And (5) gastroscopy result: no obvious inflammation and bile are seen in the gastroscope. B ultrasonic wave shows that the gallbladder wall is slightly rough and disappears.
Example 8
In whichever patient, male, 69 years old, the epigastric region is distended and stuffy for more than 1 month. Distending and stuffy feeling in the stomach, hunger before meal, belching, gastric upset, nausea, acid regurgitation, white and greasy tongue coating, and asthenia. Electronic gastroscope prompting: reflux gastritis. B ultrasonic wave shows that the gallbladder wall is slightly rough. And (3) Western diagnosis: reflux gastritis;
prescription: 30g of desmodium, 15g of scutellaria baicalensis, 6g of coptis chinensis, 15g of dandelion, 15g of fructus trichosanthis, 15g of ginger processed pinellia tuber, 10g of dried orange peel, 10g of medicated leaven, 10g of costustoot, 10g of fructus aurantii, 15g of codonopsis pilosula, 15g of poria cocos and 6g of honey-fried licorice root.
The preparation is taken orally 15-30 min before meal, and 400ml of the decoction is taken in water every 1 dose/day, 200ml of the decoction is taken every time, 2 times a day. Order to have a light diet, harmonize emotion and work and ease. After continuous taking for 30 days, the main symptoms are basically eliminated, and the result of repeated examination by a gastroscope is as follows: no obvious inflammation and bile are seen in gastroscopy, and no regurgitation is seen at pyloric opening. B-ultrasonic wave shows that the gallbladder wall is slightly rough
Example 8
Preparation of powder
The following amounts of raw materials were weighed:
300g of desmodium, 150g of scutellaria baicalensis, 60g of coptis chinensis, 150g of dandelion, 150g of fructus trichosanthis, 150g of ginger processed pinellia tuber, 100g of dried orange peel, 100g of medicated leaven, 100g of costustoot, 100g of fructus aurantii, 150g of codonopsis pilosula and 60g of honey-fried licorice root.
Drying the above Chinese medicinal materials, pulverizing, grinding, and mixing.
Example 9
Preparation of tablets
The following amounts of Chinese medicinal materials are weighed:
600g of longhairy antenoron herb, 150g of baical skullcap root, 60g of golden thread, 150g of dandelion, 150g of complete snakegourd fruit, 150g of ginger processed pinellia tuber, 100g of dried orange peel, 100g of medicated leaven, 100g of costustoot, 100g of bitter orange, 150g of astragalus root and 60g of honey-fried licorice root.
Example 10
Preparation of capsules
The following amounts of Chinese medicinal materials are weighed:
300g of desmodium, 150g of scutellaria baicalensis, 60g of coptis chinensis, 150g of dandelion, 150g of fructus trichosanthis, 150g of ginger processed pinellia tuber, 100g of dried orange peel, 100g of medicated leaven, 100g of costustoot, 100g of fructus aurantii, 150g of astragalus mongholicus, 150g of poria cocos and 60g of honey-fried licorice root.
Pulverizing the above Chinese medicinal materials, mixing, adding water to submerge the powder, heating and decocting for l hr, filtering, decocting the residue with water for half an hour, mixing the decoctions, concentrating, adding starch, granulating, and making into capsule.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, and simplifications are intended to be included in the scope of the present invention.

Claims (10)

1. A traditional Chinese medicine composition for treating gastritis is characterized by comprising the following components: herba Lysimachiae, radix Scutellariae, rhizoma Coptidis, herba Taraxaci, fructus Trichosanthis, rhizoma Pinelliae Preparada, pericarpium Citri Reticulatae, Massa Medicata Fermentata, radix aucklandiae, fructus Aurantii, and radix Codonopsis.
2. The Chinese medicinal composition of claim 1, wherein the Chinese medicinal composition further comprises one or more of radix astragali, Poria, and radix Glycyrrhizae Preparata.
3. The traditional Chinese medicine composition of claim 1, wherein the traditional Chinese medicine composition comprises: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of costustoot, 3-80 parts of fructus aurantii and 3-50 parts of codonopsis pilosula.
4. The traditional Chinese medicine composition of claim 4, wherein the traditional Chinese medicine composition further comprises 3-80 parts by weight of radix astragali.
5. The traditional Chinese medicine composition of claim 5, wherein the traditional Chinese medicine composition comprises: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of elecampane, 3-80 parts of fructus aurantii, 3-50 parts of astragalus membranaceus and 3-80 parts of honey-fried licorice root.
6. The Chinese medicinal composition according to any one of claims 1 to 6, wherein the Chinese medicinal composition further comprises one or more of clove, calyx kaki and immature bitter orange.
7. The Chinese medicinal composition according to any one of claims 1 to 6, wherein the Chinese medicinal composition further comprises one or more of raw rhubarb and raw polygonum multiflorum.
8. The Chinese medicinal composition according to any one of claims 1 to 6, wherein the Chinese medicinal composition further comprises one or more of radix pseudostellariae, Chinese yam and bighead atractylodes rhizome.
9. The Chinese medicinal composition according to any one of claims 1 to 6, wherein the Chinese medicinal composition further comprises one or more of cuttlebone and oriental wormwood.
10. The invention relates to a traditional Chinese medicine compound preparation for treating reflux gastritis, which takes the following raw materials or water extracts of the following raw materials or water extracts as active ingredients, and the raw materials comprise the following components in parts by weight: 5-80 parts of desmodium, 5-50 parts of scutellaria baicalensis, 3-50 parts of coptis chinensis, 3-50 parts of dandelion, 3-50 parts of fructus trichosanthis, 3-50 parts of ginger processed pinellia, 3-50 parts of dried orange peel, 3-80 parts of medicated leaven, 3-80 parts of costustoot, 3-80 parts of fructus aurantii, 3-50 parts of codonopsis pilosula and 3-80 parts of honey-fried licorice root.
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Citations (3)

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CN101011557A (en) * 2007-01-24 2007-08-08 兰州大学 Chinese medicinal composition for treating gastroesophageal reflux disease
CN101757336A (en) * 2008-11-20 2010-06-30 赵欣 Formula of traditional Chinese medicine for treating chronic gastritis
CN103006954A (en) * 2013-01-18 2013-04-03 黑龙江中医药大学 Preparation method of traditional Chinese medicine for treating accumulation of phlegm-heat in chest

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