CN114832085A - 一种治疗腰椎间盘突出的中药组合物及其应用、中药热敷包及其制备方法 - Google Patents
一种治疗腰椎间盘突出的中药组合物及其应用、中药热敷包及其制备方法 Download PDFInfo
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- CN114832085A CN114832085A CN202210449884.3A CN202210449884A CN114832085A CN 114832085 A CN114832085 A CN 114832085A CN 202210449884 A CN202210449884 A CN 202210449884A CN 114832085 A CN114832085 A CN 114832085A
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- chinese medicine
- hot compress
- radix
- disc herniation
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Abstract
本发明属于中药技术领域,尤其为一种治疗腰椎间盘突出的中药组合物及其应用、中药热敷包及其制备方法,通过将甲珠、牛蒡子、独活、穿破石、蔓荆子、刘寄奴、红花、防风、甘草、没药、蜈蚣、川椒、白芷、川断、丹参、透骨草、当归、木香、冰片、土鳘虫、老姜加入鸸鹋油中浸泡、煎煮,然后将熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂加入搅拌均匀,制成膏状装袋,能够重复使用,在使用时,通过热敷方式治疗腰椎间盘突出病症,在热敷作用下,皮肤毛孔扩张,且鸸鹋油具有强渗透性,促进各中药成分进入体内并作用于患者病变部位,经过大量临床应用显示,该治疗腰椎间盘突出的中药热敷包疗效明显,并且为外用方式,使用比较方便。
Description
技术领域
本发明属于中药技术领域,具体涉及一种治疗腰椎间盘突出的中药组合物及其应用、中药热敷包及其制备方法。
背景技术
腰椎间盘突出病症是较为常见的疾患之一,腰椎间盘突出病症与生活和工作习惯有关,常发于25-50岁年龄段,主要是因为这个年龄段人群的生活、工作和活动较多,与此同时,该年龄段人群的腰椎间盘纤维环和髓核已经开始退化,特别是从事的工作存在久坐、弯腰很久现象的人群,更易出现腰椎间盘突出病症。
腰椎间盘突出会导致腰痛、大腿放射痛,甚至难以正常行走,严重影响工作和正常生活。目前常见的治疗腰椎间盘突出的方法有:(1)卧床休息,并加以牵引治疗进行保守治疗,该治疗方式对初发人群有一定治疗效果,但是治疗时间长,疗效不明显,容易复发;(2)通过硫酸软骨素改善患病腰间盘结构,以及采用注射皮质激素进行抗炎治疗,该方法具有一定风险,疗效因人而异;(3)采用手术治疗,该方法具有一定后遗症的风险,并且比较痛苦。
中医作为一种调理治疗的方式,治疗方式比较温和,能够降低治疗痛苦,并且合理的中药配方具有良好的疗效,为此,有必要提供一种用于治疗腰椎间盘突出的中药。目前也存在一些治疗腰间盘突出的中药药方,一般为饮剂,且各家有各自不同药方,疗效也难以考察。
发明内容
本发明旨在提供一种治疗腰椎间盘突出的中药组合物及其应用、中药热敷包及其制备方法,解决现有技术中腰椎间盘突出病症病程长、治疗痛苦、存在治疗副作用的技术问题。
为解决上述技术问题,本发明采用以下技术方案:
提供一种治疗腰椎间盘突出的中药组合物,所述中药组合物由以下药物原料制成:甲珠5~15克、牛蒡子10~20克、独活5~15克、穿破石10~20克、蔓荆子10~20克、刘寄奴10~20克、红花5~15克、防风5~15克、甘草2~5克、没药5~15克、蜈蚣2~4条、川椒10~20克、白芷5~15克、川断5~15克、丹参25~35克、透骨草5~15克、当归10~20克、木香15~25克、熊胆粉2~4克、冰片10~20克、土鳘虫15~25个、水杨酸甲脂5~15毫升、麝香草酚3~7克、老姜20~30克、托玛琳粉5~15克、鸸鹋油750~850克。
优选的,所述中药组合物由以下药物原料制成:甲珠10克、牛蒡子15克、独活10克、穿破石15克、蔓荆子15克、刘寄奴15克、红花10克、防风10克、甘草5克、没药10克、蜈蚣3条、川椒15克、白芷10克、川断10克、丹参30克、透骨草10克、当归15克、木香20克、熊胆粉3克、冰片15克、土鳘虫20个、水杨酸甲脂10毫升、麝香草酚5克、老姜25克、托玛琳粉10克、鸸鹋油800克。
本发明还提供上述中药组合物在制备用于治疗腰椎间盘突出的药物中的应用。
本发明还提供一种治疗腰椎间盘突出的中药热敷包,该中药热敷包采用上述的中药组合物制备成。
本发明还提供上述治疗腰椎间盘突出的中药热敷包的制备方法,包括以下步骤:
(1)将甲珠、牛蒡子、独活、穿破石、蔓荆子、刘寄奴、红花、防风、甘草、没药、蜈蚣、川椒、白芷、川断、丹参、透骨草、当归、木香、冰片、土鳘虫、老姜加入鸸鹋油中浸泡24~72小时;
(2)对步骤(1)浸泡后的混合药物文火煎煮30~90分钟;
(3)步骤(2)中煎煮后的混合药物自然冷却至40~60℃时,加入熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂,搅拌均匀,直至成膏状;
(4)将步骤(3)中煎煮后的混合药物装入热敷袋,冷却后即得中药热敷包。
与现有技术相比,本发明的有益效果是:
1、该治疗腰椎间盘突出的中药组合物精心筛选二十多味中药材加上鸸鹋油,鸸鹋油具有很强的渗透性,能够使中药有效成份作用于病患处,促进腰椎间盘突出位置的血液循环,增强自修复能力,逐步治疗腰椎间盘突出,避免手术、拉伸牵引等方式带来的痛苦及副作用。
2、该中药热敷包通过将甲珠、牛蒡子、独活、穿破石、蔓荆子、刘寄奴、红花、防风、甘草、没药、蜈蚣、川椒、白芷、川断、丹参、透骨草、当归、木香、冰片、土鳘虫、老姜加入鸸鹋油中浸泡、煎煮,然后将熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂加入搅拌均匀,制成膏状装袋,能够重复使用,在使用时,通过热敷方式治疗腰椎间盘突出病症,在热敷作用下,皮肤毛孔扩张,且鸸鹋油具有强渗透性,促进各中药成分进入体内并作用于患者病变部位,能够有效缓解腰椎间盘突出患者的疼痛,促进患病位置血液循环,经过大量临床应用显示,该治疗腰椎间盘突出的中药热敷包疗效明显,并且为外用方式,使用比较方便。
具体实施方式
下面将结合本发明实施例,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明止痛软膏剂中组分的药理分析:甲珠:攻毒散结,疏道经络;牛蒡子:疏风散热,散诸结节、筋骨烦热毒;独活:祛风排湿,散寒止痛,关节屈伸不利,腰膝酸软;穿破石:散瘀消肿,祛风通络,止麻痛,风冷疼痛;蔓荆子:疏散风热,清利头目;刘寄奴:破血通经,敛疮消肿,消食化积;红花:活血通经,散瘀止痛;防风:祛风,除湿,止痛,止痉;甘草:抗酸,镇咳化痰;没药:消肿生肌,理气止痛,活血祛瘀;蜈蚣:息风镇痉,通络止痛;川椒:温中止痛,止痒,散寒;白芷:除湿排脓,生肌,活血止痛;川断:补肝肾,强筋骨,调血脉;丹参:活血,祛瘀止痛,凉血安神;透骨草:祛风除湿,舒筋活血,筋骨挛缩;当归:温经散寒,补血养血,活血止痛;木香:保肝,抗菌,抗肿瘤,祛湿舒筋;熊胆粉:惊风抽搐,清热,平肝,明目,止痛消肿;冰片:消炎化癒;土鳘虫:化淤血,通乳,续筋,抗凝血,抗血栓,调血脂,活络筋骨;水杨酸甲脂:抗真菌,浅部真菌,抗瘙痒症;麝香草酚:汗疱疹及皮肤瘙痒症;老姜:新陈代谢,缓解疲劳,保养肾脏,足进血液流通;托玛琳:消炎镇痛,活血化瘀;鸸鹋油:具有深层渗透能力、止痛、对关节炎症消炎镇痛。
下面实施例中未注明具体条件的部分,按照常规条件或制造商建议的条件进行,所用试剂或仪器未注明生产厂商的,均为可以通过市售购买可获得的常规产品。
实施例1
一种治疗腰椎间盘突出的中药组合物,该中药组合物由以下药物原料制成:甲珠5克、牛蒡子10克、独活5克、穿破石10克、蔓荆子10克、刘寄奴10克、红花5克、防风5克、甘草2克、没药5克、蜈蚣2条、川椒10克、白芷5克、川断5克、丹参25克、透骨草5克、当归10克、木香15克、熊胆粉2克、冰片10克、土鳘虫15个、水杨酸甲脂5毫升、麝香草酚3克、老姜20克、托玛琳粉5克、鸸鹋油750克。
实施例2
一种治疗腰椎间盘突出的中药组合物,该中药组合物由以下药物原料制成:甲珠10克、牛蒡子15克、独活10克、穿破石15克、蔓荆子15克、刘寄奴15克、红花10克、防风10克、甘草5克、没药10克、蜈蚣3条、川椒15克、白芷10克、川断10克、丹参30克、透骨草10克、当归15克、木香20克、熊胆粉3克、冰片15克、土鳘虫20个、水杨酸甲脂10毫升、麝香草酚5克、老姜25克、托玛琳粉10克、鸸鹋油800克。
实施例3
一种治疗腰椎间盘突出的中药组合物,该中药组合物由以下药物原料制成:甲珠15克、牛蒡子20克、独活15克、穿破石20克、蔓荆子20克、刘寄奴20克、红花15克、防风15克、甘草5克、没药15克、蜈蚣4条、川椒20克、白芷15克、川断15克、丹参35克、透骨草15克、当归20克、木香25克、熊胆粉4克、冰片20克、土鳘虫25个、水杨酸甲脂15毫升、麝香草酚7克、老姜30克、托玛琳粉15克、鸸鹋油850克。
本发明还提供上述中药组合物在制备用于治疗腰椎间盘突出的药物中的应用,比如,可采用上述中药组合物制备治疗腰椎间盘突出的中药热敷包。
实施例4
一种治疗腰椎间盘突出的中药热敷包,该治疗腰椎间盘突出的中药热敷包采用实施例1中的中药组合物制备。
该治疗腰椎间盘突出的中药热敷包的制备方法包括以下步骤:
(1)将甲珠、牛蒡子、独活、穿破石、蔓荆子、刘寄奴、红花、防风、甘草、没药、蜈蚣、川椒、白芷、川断、丹参、透骨草、当归、木香、冰片、土鳘虫、老姜加入鸸鹋油中浸泡24小时。
(2)对步骤(1)浸泡后的混合药物文火煎煮30分钟。
(3)步骤(2)中煎煮后的混合药物自然冷却至40℃时,加入熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂,搅拌均匀,直至成膏状。
这里的赋形剂采用凡士林。
(4)将步骤(3)中煎煮后的混合药物装入热敷袋,冷却后即得中药热敷包。
这里的热敷袋采用透气的无纺布热敷袋,而冷却后的中药热敷包再次加热到45℃左右时处于柔软可塑形状态,能够被重复使用。
实施例5
一种治疗腰椎间盘突出的中药热敷包,本实施例中治疗腰椎间盘突出的中药热敷包采用实施例2中的中药组合物制备。
该治疗腰椎间盘突出的中药热敷包的制备方式与实施例4不同之处在于:在步骤(1)中浸泡时长为48小时;在步骤(2)中煎煮时长为60分钟;在步骤(3)中,对步骤(2)中煎煮后的混合药物自然冷却至45℃时加入熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂。
实施例6
一种治疗腰椎间盘突出的中药热敷包,本实施例中治疗腰椎间盘突出的中药热敷包采用实施例3中的中药组合物制备。
该治疗腰椎间盘突出的中药热敷包的制备方式与实施例4不同之处在于:在步骤(1)中浸泡时长为72小时;在步骤(2)中煎煮时长为90分钟;在步骤(3)中,对步骤(2)中煎煮后的混合药物自然冷却至60℃时加入熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂。
该治疗腰椎间盘突出的中药热敷包使用方式如下:将该治疗腰椎间盘突出的中药热敷包置于蒸锅加热,或者将该治疗腰椎间盘突出的中药热敷包浸水后置于微波炉加热,加热至45℃左右的中药热敷包敷在患者后腰位置。
中药热敷包加热后,外部温度一般不超过47℃,以防止烫伤皮肤。在对中药热敷包加热时,可在热敷包内部被充分加热后冷却到适宜温度再对人体进行热敷,避免热敷包外部温度过高而内部没有被加热。
采用该治疗腰椎间盘突出的中药热敷包热敷时,在热敷作用下,皮肤毛孔扩张,且鸸鹋油具有强渗透性,促进各中药成分进入体内并作用于患者病变部位,能够有效缓解腰椎间盘突出患者的疼痛,促进患病位置血液循环,增强自修复能力,逐步治疗腰椎间盘突出,避免手术、拉伸牵引等方式带来的痛苦及副作用。该治疗腰椎间盘突出的中药热敷包为外用方式,使用方便、疗效明显,相关临床试验资料如下:
共记录了60名腰椎间盘突出患者采用该中药热敷包治疗腰椎间盘突出的过程,年龄在30岁至65之间,男性45人,女性15人,经腰椎CT检查均确诊为腰椎间盘突出病症,其中病程最长的达10年之久,自诉中间有过间断性改善,多次复发;有患者采用牵引和倒走的方式治疗和锻炼,有一定改善,但仍然疼痛明显,且大腿有放射性疼痛。
以上患者共分为三组,20名一组,分别采用上述实施例4、5、6中的中药热敷包按照以下方式进行治疗:将中药热敷包加热敷于后腰上腰间盘所在位置,30分钟后取下,三天热敷两次,一个月为一个疗程,治疗效果如下表1所示:
表1-中药热敷包对腰椎间盘突出患者的治疗效果统计表
以上治疗效果统计表1中,治愈的评判标准为:治疗2个疗程之后,腰椎间盘突出带来的腰痛、腿痛等症状消失,抬腿伸膝无障碍;有显著疗效的评判标准为:治疗2个疗程之后,腰椎间盘突出带来的腰痛、腿痛等症状明显改善,抬腿伸膝稍有阻碍;病症得到缓解的评判标准为:治疗2个疗程之后,腰椎间盘突出带来的腰痛、腿痛等症状获得改善,还有比较明显痛感;无效的评判标准为:治疗2个疗程之后,腰椎间盘突出带来的腰痛、腿痛等症状没有任何变化。
由以上治疗效果统计表1可见,分组1和分组2的有效率为95%,分组3的有效率为90%,总有效率达93.3%,可见,该中药热敷包对腰椎间盘突出病症具有良好的治疗效果。
需要说明的是,在本文中,诸如术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含,从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素,而且还包括没有明确列出的其他要素,或者是还包括为这种过程、方法、物品或者设备所固有的要素。
尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解,在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。
Claims (5)
1.一种治疗腰椎间盘突出的中药组合物,其特征在于,所述中药组合物由以下药物原料制成:甲珠5~15克、牛蒡子10~20克、独活5~15克、穿破石10~20克、蔓荆子10~20克、刘寄奴10~20克、红花5~15克、防风5~15克、甘草2~5克、没药5~15克、蜈蚣2~4条、川椒10~20克、白芷5~15克、川断5~15克、丹参25~35克、透骨草5~15克、当归10~20克、木香15~25克、熊胆粉2~4克、冰片10~20克、土鳘虫15~25个、水杨酸甲脂5~15毫升、麝香草酚3~7克、老姜20~30克、托玛琳粉5~15克、鸸鹋油750~850克。
2.根据权利要求1所述的治疗腰椎间盘突出的中药组合物,其特征在于,所述中药组合物由以下药物原料制成:甲珠10克、牛蒡子15克、独活10克、穿破石15克、蔓荆子15克、刘寄奴15克、红花10克、防风10克、甘草5克、没药10克、蜈蚣3条、川椒15克、白芷10克、川断10克、丹参30克、透骨草10克、当归15克、木香20克、熊胆粉3克、冰片15克、土鳘虫20个、水杨酸甲脂10毫升、麝香草酚5克、老姜25克、托玛琳粉10克、鸸鹋油800克。
3.权利要求1或2所述的中药组合物在制备用于治疗腰椎间盘突出的药物中的应用。
4.一种治疗腰椎间盘突出的中药热敷包,其特征在于,该中药热敷包采用权利要求1或2所述的中药组合物制备成。
5.权利要求4所述的治疗腰椎间盘突出的中药热敷包的制备方法,其特征在于,包括以下步骤:
(1)将甲珠、牛蒡子、独活、穿破石、蔓荆子、刘寄奴、红花、防风、甘草、没药、蜈蚣、川椒、白芷、川断、丹参、透骨草、当归、木香、冰片、土鳘虫、老姜加入鸸鹋油中浸泡24~72小时;
(2)对步骤(1)浸泡后的混合药物文火煎煮30~90分钟;
(3)步骤(2)中煎煮后的混合药物自然冷却至40~60℃时,加入熊胆粉、托玛琳粉、麝香草酚、水杨酸甲脂以及赋形剂,搅拌均匀,直至成膏状;
(4)将步骤(3)中煎煮后的混合药物装入热敷袋,冷却后即得中药热敷包。
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