CN114797696A - Extreme manufacturing equipment of micro-droplet three-dimensional sphere structure and using method - Google Patents
Extreme manufacturing equipment of micro-droplet three-dimensional sphere structure and using method Download PDFInfo
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Abstract
The invention belongs to the technical field of soft condensed state substance manufacturing, and particularly relates to extreme manufacturing equipment of a micro-droplet three-dimensional sphere structure and a using method thereof. The system comprises a laser micro-nano processing system, a micro-fluidic chip system and a real-time observation system. The using method comprises the following steps: step 1: obtaining target micro-droplets, and enabling the tunable laser to emit laser spots; step 2: hitting the focused laser spot to the boundary of the target droplet; and step 3: exposing the interlayer cavity with laser for several seconds, injecting the aqueous solution into the target microdroplet to form a sub-droplet, and completing the assembly of the spherical structure of the target microdroplet in the interlayer cavity; and 4, step 4: synchronously with the step 3, illuminating by a light source and observing by a CCD camera; and 5: the injector moves the droplets of the processed soft substance into a droplet collector. The invention can control the self-assembly of the micro-nano particles into different three-dimensional morphological structures in the microdroplet, and has important scientific and technical value for promoting the progress of extreme manufacturing technology of microdroplet spherical structures.
Description
Technical Field
The invention belongs to the technical field of soft condensed state substance manufacturing, and particularly relates to extreme manufacturing equipment of a micro-droplet three-dimensional sphere structure and a using method thereof.
Background
The soft substance is also called as soft condensed substance, and includes liquid crystal, colloid, macromolecule, particulate substance, life system substance (such as DNA, protein, cell membrane), emulsion, etc., and is widely existed and far affected in nature, life, daily life and production. In recent decades, the micro-nano processing technology for solid materials realizes the integration of complex electronic functions on micron-scale electronic devices, and contributes to the rapid development of modern electronic industry, particularly semiconductor industry. As the macroscopic characteristics of the intelligent flexible material depend on chemical components and microstructures of the intelligent flexible material, the micro-nano processing technology for liquid and soft material has important scientific and technical values in the fields of photonics, optoelectronics, flexible electronics, intelligent sensing, chemical engineering, medicine, biopharmaceuticals and the like. But in contrast, its development is rather delayed.
However, at present, droplet microfluidic technology is generally adopted for micro-nano processing of fluids and soft substances, and the structural design of a microfluidic chip is limited by the special physical properties of the materials such as fluidity, interfacial tension, diffusion effect and the like, and only a few simpler droplet structures can be assembled by virtue of the droplet microfluidic technology: for example, a sub-droplet of one material nests within a droplet of another material, flexible assembly of droplet sphere structures is not possible.
The laser injection technology is a micro-nano processing technology aiming at fluid and soft substances emerging in recent years, and the main principle is that a Gaussian beam is utilized to irradiate the surface of a liquid crystal (soft substance) micro-droplet in an aqueous solution to form mechanical force to inject the aqueous solution into the liquid crystal micro-droplet to form a sub-droplet by virtue of the interaction between light and the substances. The technology expands laser micro-nano manufacturing to the extreme manufacturing field of fluid and soft substances, and shows flexibility and complexity far exceeding those of the traditional micro-fluidic process.
However, the droplet ball structure assembled by this technique is simple: the micro-nano particles are radially distributed along the sphere in the liquid crystal microdroplet, so that the possibility of subsequent application and development is greatly restricted. If the potential of material self-organization can be further developed, the self-assembly of the micro-nano particles in the micro-droplets into different three-dimensional morphological structures is controlled, and the method has important scientific and technical values for promoting the progress of extreme manufacturing technology and potential application development of the micro-droplet spherical structure.
Disclosure of Invention
Aiming at the problems in the prior art, the invention constructs an extreme manufacturing system of a microdroplet three-dimensional spherical structure, carries out micro-nano processing on soft substance microdroplets with different topological defect structures through a laser injection system, and leads injected micro-nano particles to be self-organized and arranged in the soft substance microdroplets to form a pre-designed three-dimensional crystal structure by virtue of the diversity of the topological defect structures of the soft substance microdroplets, thereby realizing the purpose of assembling the soft substance microdroplet complex spherical structure; the extreme manufacturing system of the droplet sphere structure can be used for processing polynuclear soft material droplets (water-in-oil-in-water), and the processing method can still be feasible when the aqueous solution and the soft material (oil phase) in the system are simply assembled to remove oil-in-water-in-oil (O/W/O) polynuclear droplets.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the utility model provides an extreme manufacture equipment of three-dimensional spheroid structure of droplet, includes that laser receives processing system, micro-fluidic chip system, real-time observation system a little, the processing system is received including tunable laser, aperture diaphragm, dichroic mirror and automatically controlled formula translation platform a little to laser, the aperture diaphragm sets up in tunable laser's left side, the dichroic mirror sets up in the left side of aperture diaphragm, automatically controlled formula translation platform sets up in the top of dichroic mirror, micro-fluidic chip system sets up on automatically controlled formula translation platform, real-time observation system includes light source subsystem and camera subsystem, the light source subsystem sets up in the top of micro-fluidic chip system, the camera subsystem communicates with each other with the dichroic mirror.
Preferably, the microfluidic chip system comprises an upper substrate and a lower substrate, a cavity interlayer channel is arranged between the upper substrate and the lower substrate, one end of the cavity interlayer channel is an injection port of the soft substance micro-droplet water solution, the injection port is connected with an injector through a connecting pipe, the other end of the cavity interlayer channel is an outlet end, and the outlet end is connected with a droplet collector through a connecting pipe.
Preferably, the camera subsystem includes a light source disposed at an uppermost end of the extreme manufacturing system and a collection mirror disposed between the light source and the microfluidic chip system.
Preferably, the camera subsystem comprises a microscope objective, a reflecting mirror and a CCD camera, the microscope objective is arranged between the electrically controlled translation stage and the dichroic mirror, the reflecting mirror is arranged below the dichroic mirror, and the CCD camera is arranged at the right side of the reflecting mirror.
A method of using an extreme manufacturing apparatus for droplet three-dimensional sphere structures, comprising the steps of:
step 1: the material of the soft substance microdroplet is E7 liquid crystal doped with different concentrations R811 to obtain target microdroplets, the micro-fluid peristaltic injection pump controls the injector to send the aqueous solution containing the target microdroplets into the micro-fluid control chip for processing, then the tunable laser emits a continuous laser beam with a large diameter, and the laser beam is focused by the aperture diaphragm, the dichroic mirror and the microscope objective to obtain laser spots with a small diameter;
and 2, step: the focused laser light spot is shot to the boundary of a target micro-droplet of an interlayer cavity of the micro-fluidic chip;
and step 3: exposing the laser for several seconds to generate mechanical force at the target droplet interface, injecting the aqueous solution around the target droplet into the target droplet interface to form sub-droplets, and spontaneously arranging the injected sub-droplets along the topological structure in the droplet so as to process the spherical structure of the target droplet in the interlayer cavity;
and 4, step 4: when the micro-fluidic chip is processed in the step 3, the dynamic structure appearance of the target micro-droplet in the micro-fluidic chip can be observed in real time through the CCD camera under the illumination of the light source;
and 5: the syringe is driven by a microfluidic peristaltic injection pump and droplets of processed soft matter are moved into a drop collector and processing continues with the next.
Preferably, in step 1, the target droplet is doped with 0.1 wt% of R811, and the target droplet is a first target soft substance droplet at a doping concentration at which a steady state is achieved, and the aqueous solution in step three is doped with 0.2 wt% of surfactant SDS, so that the first target soft substance droplet can be stably suspended in water, and the topological structure of the first target soft substance droplet at the steady state is a topological line uniformly distributed near the surface of the first target soft substance droplet, and the topological lines are connected end to form a circular ring;
in the third step, the aqueous solution is injected into the target soft substance droplet I through the laser injection system to form a first sub-droplet, the first sub-droplet is captured by the topological line and moves along the space geometric form of the first sub-droplet, and the topological line is completely occupied by the sub-droplet particles to form a particle necklace-shaped structure along with the injection of the laser.
Preferably, in step 1, the target droplet is doped with 0.05 wt% of R811, and the doping concentration is 0.05 wt% of the target soft substance droplet two when reaching a steady state, and the topological structure is a topological point, the aqueous solution in step three is doped with 0.2 wt% of surfactant SDS, and sodium lauryl sulfate can stably suspend the target soft substance droplet two in water;
in the third step, when the laser exposure is 5s, the aqueous solution is injected into the second droplet of the target soft substance to form a second sub-droplet, the second sub-droplets are influenced by the long-range elastic interaction force of the topological point, the first injected second sub-droplets are captured by the topological point and attract the rest of the second sub-droplets to form a droplet chain, meanwhile, the liquid crystal molecules in the second target soft matter droplet are arranged from the topological point to the surface of the second sphere vertical to the second target soft matter droplet, under the elastic action of the liquid crystal molecules, the injected sub-droplets can spontaneously organize to form droplet chains, and the arrangement direction of the droplet chain in the spherical space in the second target soft substance droplet is consistent with the arrangement direction of liquid crystal molecules, and the injected second sub-droplets form a spiral micro-nano particle chain along the arrangement direction of the molecules in the second target soft substance droplet along with the injection of the laser.
Preferably, the E7 liquid crystal is doped with a heat absorbing material.
Compared with the prior art, the invention has the beneficial effects that:
1. peripheral aqueous solution is injected into the closed soft substance microdroplet to form a specific number of sub-droplets (micro-nano size) by controlling parameters such as the exposure position, the exposure power, the time and the like of laser, and the arrangement of the sub-droplets in a pre-designed ordered structure in a three-dimensional space in the soft substance microdroplet is controlled and induced through the elastic action of soft substance molecules, so that the purpose of processing the spherical structure of the soft substance microdroplet is achieved;
2. the topological structure of the soft substance micro-drop in a stable state is stable, and the sub-drops (micro-nano scale) are induced and controlled by the topological structure to be distributed along a pre-designed crystal structure in a three-dimensional space (the sub-drops are arranged along the topological structure and the soft substance molecular direction);
3. the diversity of the topological defect structures of the microdroplets of the soft material (various topological points and various forms of staggered lines) under different doping concentrations is effectively utilized and used as a template to process microdroplet complex spherical structures;
4. the geometric form of the self-organized assembled droplet spherical structure by means of the materials is greatly expanded, and because each droplet can be observed and controlled independently and perform a specific function, the diversified spherical structure provides more possibilities for subsequent application development.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
In the drawings:
FIG. 1 is a schematic diagram of an overall optical path structure of a droplet three-dimensional sphere structure extreme manufacturing system according to the present invention;
FIG. 2 is a side view of a microfluidic chip portion of a droplet three-dimensional sphere structure extreme manufacturing system according to the present invention;
FIG. 3 is a schematic diagram of several typical topological defect structures possessed by droplets of soft matter and their corresponding microstructural texture maps;
FIG. 4 is a schematic diagram of the topological line-fitted droplet sphere within the droplet of soft substance according to example 2;
FIG. 5 is a schematic diagram of topological line-assembled droplet spheres within a droplet of soft substance according to example 3;
FIG. 6 is a flow chart of a method for using the droplet three-dimensional sphere structure extreme manufacturing system of the present invention;
in the figure: 1. a tunable laser; 2. an aperture diaphragm; 3. a dichroic mirror; 4. a microscope objective; 5. an electrically controlled translation stage; 6. a microfluidic chip; 7. a target droplet; 8. a condenser lens; 9. observing a light source; 10. a mirror; 11. a CCD camera; 12. an upper substrate; 13. a lower substrate; 14. a microfluidic chip cavity; 15. an injection port; 16. an outlet end; 17. droplets of soft material to be processed; 18. droplets of a soft substance of interest in the process; 19. droplets of processed soft matter; 20. a microfluidic peristaltic injection pump; 21. a connecting pipe; 22. an injector; 23. a droplet collector; 24. a first droplet of a target soft substance; 25. a target droplet-a topological defect structure; 26. a topological line; 27. injecting the processed microdroplet I by laser; 28. a first sub-droplet; 29. microdroplet-a laser processed sphere structure; 30. a second droplet of the target soft substance; 31. a topological point; 32. a target microdroplet two-topological defect structure; 33. injecting the processed microdroplet II by laser; 34. a micro-nano particle chain; 35. and a second sub-droplet.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
Example 1:
referring to attached figures 1 and 2, an extreme manufacturing device of a microdroplet three-dimensional sphere structure comprises a laser micro-nano processing system, a micro-fluidic chip system 6 and a real-time observation system, the laser micro-nano processing system comprises a tunable laser 1, an aperture diaphragm 2, a dichroic mirror 3 and an electric control type translation stage 5, the aperture stop 2 is arranged on the left side of the tunable laser 1, the dichroic mirror 3 is arranged on the left side of the aperture stop 2, the electric control type translation stage 5 is arranged above the dichroic mirror 3, the micro-fluidic chip system 6 is arranged on the electric control type translation stage 5, the soft matter micro-drop is positioned in the micro-fluidic chip system 6, the real-time observation system comprises a light source subsystem and a camera subsystem, the light source subsystem is arranged above the microfluidic chip system 6, and the camera subsystem is communicated with the dichroic mirror 3.
The microfluidic chip system 6 comprises an upper substrate 12 and a lower substrate 13, a cavity interlayer channel 14 is arranged between the upper substrate 12 and the lower substrate 13, as shown in fig. 1, a soft substance droplet 17 to be processed, a target soft substance droplet 18 in processing and a processed soft substance droplet 19 are arranged in the cavity interlayer channel 14, one end of the cavity interlayer channel 14 is an injection port 15 of a soft substance droplet water solution, the injection port 15 is connected with an injector 22 through a connecting pipe 21, the inner diameter of the connecting pipe 21 is 0.1mm-4mm, the injector 22 is connected with a microfluidic peristaltic injection pump 20, by means of which the make-and-break and the flow rate of the water solution in the injector into the microfluidic chip cavity are accurately controlled, in the embodiment, the model is Harvardpump 33, which accurately controls the make-and-break and the flow rate of the water solution in the injector 22 into the cavity of the microfluidic chip system 6, the other end of the cavity interlayer channel 14 is an outlet end 16, the outlet end 16 is connected with a droplet collector 23 through a connecting pipe 21, and the sample bottle XB-YPP with the model of Xiang glass is adopted in the embodiment to achieve the purpose of collecting the processed droplet solution.
The thickness of the cavity sandwich channel 14, the injection port 15 and the outlet port 16 is 0.3-2mm, which is larger than the diameter of the soft matter droplet 18 (typically 0.01-1 mm).
The camera subsystem comprises a light source 9 and a condenser lens 8, the light source 9 is arranged at the uppermost end of the extreme manufacturing system, and the condenser lens 8 is arranged between the light source 9 and the microfluidic chip system 6.
The camera subsystem comprises a microscope objective 4, a reflecting mirror 10 and a CCD camera 11, the microscope objective 4 is arranged between the electric control type translation stage 5 and the dichroic mirror 3, the reflecting mirror 10 is arranged below the dichroic mirror 3, and the CCD camera 11 is arranged on the front side of the reflecting mirror 10.
Example 2:
a method for assembling a droplet sphere with reference to topological lines in a soft material droplet as shown in figures 1, 2, 3, 4 and 6, comprising the steps of:
step 1: the soft matter microdroplets are made of E7 (Merck company) liquid crystal doped with R811(4- (4-hexyloxybenzoyloxy) benzoic acid-R- (+) -2-octyl ester and liquid crystal chiral additive) with different concentrations (Sige Delrich company) and target microdroplets 7, an injector 22 is controlled by a microfluid peristaltic injection pump 20 to send an aqueous solution containing the target microdroplets 7 into a microfluidic chip 6 for processing, then a tunable laser 1 emits a continuous laser beam with a large diameter, and the continuous laser beam is focused by an aperture diaphragm 2, a dichroic mirror 3 and a microscope objective 4 to obtain laser spots with small diameters, wherein the typical spot diameter is 5 microns;
step 2: the focused laser spot is shot to the boundary of a target micro-droplet 7 in an interlayer cavity 14 of the micro-fluidic chip 6;
and step 3: the laser exposure for several seconds generates mechanical force at the interface of the target droplet 7, the force injects the aqueous solution around the target droplet 7 into the interface to form sub-droplets, and the injected sub-droplets spontaneously align along the topology structure in the droplet 7, so as to process the spherical structure of the target droplet 7 in the interlayer cavity 14;
and 4, step 4: when the step 3 is carried out, the dynamic structure appearance of the target micro-droplet 7 in the micro-fluidic chip 6 can be observed through the CCD camera 11 under the illumination of the light source 9;
in step 1 of this embodiment 1, the target droplet 7 is doped with 0.1 wt% of R811, and the concentration of the doped target droplet is first 24 target soft substance droplets when reaching a steady state, the aqueous solution of step three is doped with 0.2 wt% of surfactant SDS (sodium dodecyl sulfate), and the SDS (sodium dodecyl sulfate) can make the first 24 target soft substance droplets stably suspend in water, the topology structure of the first 24 target soft substance droplets when reaching the steady state is a topology line 26 uniformly distributed near the surface of the first target soft substance droplets, and the topology line 26 is connected end to form a circular ring and uniformly distributed near the surface of the spheres of a structure 25 of the first target soft substance droplets;
the E7 liquid crystal was doped with 0.1 wt% of an endothermic material (columerin-6) to allow observation of a laser spot during operation of the laser spot in the laser operation region.
In the third step described in this embodiment 1, an aqueous solution is injected into the first droplet 24 of the target soft substance by using a laser injection system to form the first sub-droplet 28, the first sub-droplet 28 is captured by the topological line 26 and moves along the spatial geometry thereof, and as the laser injection progresses, more and more first sub-droplets 28 are injected into the first target droplet 24 until the topological line 26 completely occupies a sub-structure forming a particle chain by the first sub-droplets 28, and the first target droplet 24 becomes the first droplet-laser processed sphere structure 29 after the laser processing.
Example 3:
referring to fig. 1, 2, 3, 5 and 6, a method for topological-line assembly of microsphere spheres in soft material droplets, which is different from example 2, in this example 3, step 1, a target droplet 7 is doped with 0.05 wt% of R811(4- (4-hexyloxybenzoyloxy) benzoic acid-R- (+) -2-octyl ester, liquid crystal chiral additive) at a concentration which is a second 30 target soft material droplet at steady state and has a topological structure of one topological point 31, and an aqueous solution of step three is doped with 0.2 wt% of surfactant SDS (sodium dodecyl sulfate) which can stably suspend the second 30 target soft material droplet in water.
The E7 liquid crystal was doped with 0.1 wt% of an endothermic material (columerin-6) to allow observation of a laser spot during operation of the laser spot in the laser operation region.
In the third step, when the laser exposure is 5s, the aqueous solution is injected into the second target soft substance droplet 30 to form the second sub-droplet 35, the second sub-droplet 35 is affected by the long-range elastic interaction force of the topological point 31, the first injected second sub-droplet 35 is captured by the topological point 31, and the rest of the second sub-droplets are attracted to form a droplet chain, meanwhile, the liquid crystal molecules in the second target soft substance droplet 30 are arranged along the topological point 31 to the surface perpendicular to the spherical surface of the second target soft substance droplet 30 (as shown in fig. 5, and the black line in the circle of the second target droplet topological defect structure 32), the injected second sub-droplet 35 spontaneously organizes to form a droplet chain under the elastic action of the liquid crystal molecules, and the arrangement direction of the droplet chain in the spherical space in the second target soft substance droplet 30 is consistent with the arrangement direction of the liquid crystal molecules.
Along with the progress of laser injection, the injected second sub-droplets 35 form a spiral micro-nano particle chain 34 along the molecular arrangement direction in the second target soft substance droplet 30.
In the invention, the topological structure of the closed soft substance microdroplet is fixed, the sub-droplets are injected into the microdroplet by laser in a rhythm from different high boundary positions, and the loaded microdroplet is arranged along the topological structure of the soft substance microdroplet (the topological points and topological lines refer to 2 types, but not 2 types, and have various distributed topological points and topological lines in various forms), thereby realizing the purpose of assembling the spherical structure of the soft substance microdroplet (each sub-droplet is the substructure in the microdroplet, and the purpose of assembling the spherical structure of the microdroplet is realized by controlling the spatial distribution of the sub-droplets).
In conclusion, the invention controls the position and rhythm of injecting the micro-nano particles by controlling the laser, and injects the micro-nano particles into the stable closed soft matter microdroplets with different topological defect structures, so that the micro-nano particles can be spontaneously organized into a pre-designed particle crystal structure along with the geometrical structure of the topological defect structures (topological lines or molecular arrangement), and the extreme manufacture of the soft matter microdroplets with complex spherical structures is realized.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (8)
1. An extreme manufacturing apparatus for droplet three-dimensional sphere structures, characterized by: including laser micro-nano machining system, micro-fluidic chip system (6), real-time observation system, laser micro-nano machining system includes tunable laser (1), aperture diaphragm (2), dichroic mirror (3) and automatically controlled formula translation platform (5), aperture diaphragm (2) set up in the left side of tunable laser (1), dichroic mirror (3) set up in the left side of aperture diaphragm (2), automatically controlled formula translation platform (5) set up in the top of dichroic mirror (3), micro-fluidic chip system (6) set up on automatically controlled formula translation platform (5), real-time observation system includes light source subsystem and camera subsystem, the light source subsystem sets up in the top of micro-fluidic chip system (6), the camera subsystem communicates with each other with dichroic mirror (3).
2. An extreme manufacturing apparatus of a three-dimensional sphere structure of droplets according to claim 1, characterized in that: the micro-fluidic chip system (6) comprises an upper substrate (12) and a lower substrate (13), wherein a cavity interlayer channel (14) is arranged between the upper substrate (12) and the lower substrate (13), one end of the cavity interlayer channel (14) is an injection port (15) of a soft substance micro-droplet water solution, the injection port (15) is connected with an injector (22) through a connecting pipe (21), the other end of the cavity interlayer channel (14) is an outlet end (16), and the outlet end (16) is connected with a droplet collector (23) through the connecting pipe (21).
3. An extreme manufacturing apparatus of a three-dimensional sphere structure of droplets according to claim 2, characterized in that: the camera subsystem comprises a light source (9) and a condenser lens (8), the light source (9) is arranged at the uppermost end of the extreme manufacturing system, and the condenser lens (8) is arranged between the light source (9) and the microfluidic chip system (6).
4. An extreme manufacturing apparatus of a three-dimensional sphere structure of droplets according to claim 3, characterized in that: the camera subsystem comprises a microscope objective (4), a reflector (10) and a CCD camera (11), the microscope objective (4) is arranged between the electric control type translation stage (5) and the dichroic mirror (3), the reflector (10) is arranged below the dichroic mirror (3), and the CCD camera (11) is arranged on the front side of the reflector (10).
5. Use of an extreme manufacturing apparatus of a three-dimensional sphere structure of microdroplets according to any of claims 1-4, characterized in that: the method comprises the following steps:
step 1: the material of the soft substance microdroplet is E7 liquid crystal doped with different concentrations R811 to obtain target microdroplets (7), an injector (22) is controlled by a microfluid peristaltic injection pump (20) to send aqueous solution containing the target microdroplets (7) into a microfluidic chip (6) for processing, then a tunable laser (1) emits a beam of continuous laser beam with a large diameter, and the continuous laser beam is focused by an aperture diaphragm (2), a dichroic mirror (3) and a microobjective (4) to obtain laser spots with a small diameter;
step 2: the focused laser spot is shot to the boundary of a target micro-droplet (7) of an interlayer cavity (14) of the micro-fluidic chip (6);
and step 3: laser exposure for several seconds generates mechanical force at the target droplet (7) interface, the force injects aqueous solution around the target droplet to form sub-droplets, and the injected sub-droplets spontaneously align along the topological structure in the droplet (7), so as to process the spherical structure of the target droplet (7) in the interlayer cavity (14);
and 4, step 4: during the processing in the step 3, the dynamic structure appearance of the target micro-droplets (7) in the micro-fluidic chip (6) can be observed in real time through the illumination of the light source (9) by the CCD camera (11);
and 5: the syringe (22) is driven by a microfluidic peristaltic injection pump (20) and the droplets (19) of processed soft substance are moved into a droplet collector (23) and processing continues with the next one.
6. The method of using the extreme manufacturing equipment of droplet three-dimensional sphere structure of claim 5, wherein: in the step 1, the target droplet (7) is doped with 0.1 wt% of R811, and the target droplet is a first target soft substance droplet (24) when the steady state is achieved, the aqueous solution in the step three is doped with 0.2 wt% of surfactant SDS, so that the first target soft substance droplet (24) can be stably suspended in water, the topological structure of the first target soft substance droplet (24) when the steady state is achieved is a topological line (26) uniformly distributed near the surface of the first target soft substance droplet, and the topological lines (26) are connected end to form a circular ring;
in the third step, the aqueous solution is injected into the target soft substance micro-droplet one (24) through the laser injection system to form a sub-droplet one (28), the sub-droplet one (28) can be captured by the topological line (26) and moves along the spatial geometry of the topological line, and the topological line (26) is completely occupied by the sub-droplet particles (28) to form a particle item chain-shaped structure along with the injection of the laser.
7. The method of using the extreme manufacturing apparatus of droplet three-dimensional sphere structure of claim 6, wherein: in the step 1, the target droplet (7) is doped with 0.05 wt% of R811, the doping concentration is that the target soft substance droplet II (30) reaches a steady state, the topological structure is a topological point (31), and the aqueous solution in the step three is doped with 0.2 wt% of surfactant SDS, so that the target soft substance droplet II (30) can be stably suspended in the water;
in the third step, when the laser exposure is 5s, the aqueous solution is injected into the second target soft substance droplet (30) to form a second sub-droplet (35), the second sub-droplet (35) is influenced by the long-range elastic interaction force of the topological point (31), the first injected second sub-droplet (35) is captured by the topological point (31) and attracts the rest of the second sub-droplets to form a droplet chain, meanwhile, the liquid crystal molecules in the second target soft substance droplet (30) are arranged along the topological point (31) to the surface perpendicular to the spherical surface of the second target soft substance droplet (30), under the elastic action of the liquid crystal molecules, the injected second sub-droplet (35) spontaneously organizes to form a droplet chain, the arrangement direction of the droplet chain in the spherical space in the second target soft substance droplet (30) is consistent with the arrangement direction of the liquid crystal molecules, and as the laser injection progresses, the second injected sub-droplet (35) is formed along the arrangement direction of the molecules in the second target soft substance droplet (30) A spiral micro-nano particle chain (34).
8. The method of using the extreme manufacturing apparatus of droplet three-dimensional sphere structure of claim 7, wherein: the E7 liquid crystal is doped with a heat sink material.
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| CN202210202943.7A CN114797696B (en) | 2022-03-02 | 2022-03-02 | Extreme manufacturing equipment of three-dimensional sphere structure of microdroplet and use method |
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