CN114796839B - Microneedle needle insertion device based on gravity loading - Google Patents
Microneedle needle insertion device based on gravity loading Download PDFInfo
- Publication number
- CN114796839B CN114796839B CN202210410016.4A CN202210410016A CN114796839B CN 114796839 B CN114796839 B CN 114796839B CN 202210410016 A CN202210410016 A CN 202210410016A CN 114796839 B CN114796839 B CN 114796839B
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- China
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- inner cavity
- ejector rod
- machine body
- cavity
- vertical shell
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- 230000005484 gravity Effects 0.000 title claims abstract description 17
- 238000003780 insertion Methods 0.000 title abstract description 6
- 230000037431 insertion Effects 0.000 title abstract description 6
- 239000000696 magnetic material Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 description 3
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000013271 transdermal drug delivery Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Magnetic Treatment Devices (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The microneedle needle feeder based on gravity loading comprises a vertical shell with a hollow inner cavity, wherein the upper end of the vertical shell is in threaded connection with a machine body which can be screwed in or out relative to the vertical shell, and the inner cavity of the machine body is communicated with the inner cavity of the vertical shell; the top of the machine body is provided with a push switch, and the inner cavity of the machine body is provided with a power supply and an electromagnet which are arranged up and down; the inner cavity of the vertical shell is divided into an upper cavity and a lower cavity by the diaphragm plate, and the upper cavity of the pressure head is communicated with the inner cavity of the shell; the upper cavity of the pressure head is internally provided with a push rod tail, the push rod tail is provided with a connecting rod which downwards penetrates through the through hole, the connecting rod is connected with the head of the push rod, and the bottom surface of the head of the push rod is provided with an elastic gasket which can be attached to the outline of the skin and can press the microneedle patch into the skin. The invention has controllable force, can adapt to the radian of skin and can avoid manual needle insertion.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a microneedle injector based on gravity loading.
Background
The micro-needle is fine in size and can achieve percutaneous administration without touching subcutaneous nerves, so that the micro-needle can achieve the purpose of non-dysmenorrhea percutaneous administration. In order to deliver sufficient amounts of drug to the skin, microneedle patches are often used as carriers for drug delivery without dysmenorrhea.
The microneedles are typically distributed on the microneedle patch in a manner and the size of the microneedles is small, so that the microneedle patch needs to be penetrated into the skin with a certain force and speed, otherwise the microneedles on the microneedle patch are easily broken or bent, which affects the transdermal drug delivery effect of the microneedle patch.
The needle inserting force and time of the existing microneedle needle inserting device are controllable, but the existing microneedle needle inserting device is usually used for inserting needles in a manual mode, and the influence of uneven stress of the microneedle patch caused by skin radian and contour is hardly considered. Therefore, a microneedle needle insertion device with controllable force and can adapt to skin radian and avoid manual needle insertion is necessary to be developed.
Disclosure of Invention
To overcome the above problems, the present invention provides a microneedle injector based on gravity loading.
The technical scheme adopted by the invention is as follows: the microneedle needle feeder based on gravity loading comprises a vertical shell with a hollow inner cavity, wherein the upper end of the vertical shell is in threaded connection with a machine body which can be screwed in or out relative to the vertical shell, and the inner cavity of the machine body is communicated with the inner cavity of the vertical shell; the top of the machine body is provided with a push switch, the outer side wall of the machine body is provided with an indicator lamp, the inner cavity of the machine body is provided with a power supply and an electromagnet which are arranged up and down, a magnetic coil is wound around the electromagnet, and the power supply is connected with the electromagnet, the indicator lamp and the push switch in series in sequence;
A sliding block with a certain weight is connected in the inner cavity of the vertical shell and positioned below the machine body in a sliding way, and the sliding block is made of magnetic materials; the inner wall of the inner cavity of the vertical shell is provided with a plurality of sliding grooves extending along the vertical direction at intervals along the circumferential direction, the outer wall of the sliding block is provided with a groove at the position corresponding to the sliding groove, and the groove is internally provided with a roller which is in sliding connection with the sliding groove;
The lower end of the vertical shell is connected with a pressure head, the inner cavity of the pressure head is provided with a diaphragm plate, and the center of the diaphragm plate is provided with a through hole; the diaphragm plate divides the inner cavity of the pressure head into an upper cavity and a lower cavity, and the upper cavity of the pressure head is communicated with the inner cavity of the shell; the upper cavity of the pressure head is internally provided with a push rod tail which is circular plate-shaped; the center of the bottom surface of the tail part of the ejector rod is provided with a connecting rod, the connecting rod penetrates through a through hole of the diaphragm plate to extend into a lower cavity of the pressure head and is connected with the head part of the ejector rod, and a spring is sleeved on the connecting rod and positioned between the upper surface of the diaphragm plate and the lower surface of the tail part of the ejector rod; the head of the ejector rod is in a circular plate shape, the bottom surface of the head of the ejector rod is provided with an elastic gasket, the elastic gasket has elasticity, and the elastic gasket can adapt to the skin contour and press the microneedle patch into the skin;
When the electromagnet is electrified, magnetic force is generated to attract the sliding block to lift upwards, the spring is in a natural state, the tail part of the ejector rod is jacked up, and the head part of the ejector rod is contracted in the lower cavity of the pressure head; when the electromagnet is powered off, the magnetic force disappears, the sliding block moves downwards under the action of gravity and falls on the tail part of the ejector rod, the tail part of the ejector rod is pressed downwards, the spring is in a compressed state, and the head part of the ejector rod extends out of the pressure head to press the microneedle patch into the skin.
Further, the number of the sliding grooves is four, the four sliding grooves are arranged on the inner wall of the inner cavity of the vertical shell at intervals along the circumferential direction, and the upper end and the lower end of each sliding groove extend to the top surface and the bottom surface of the shell respectively.
Further, the inner wall of the inner cavity of the vertical shell is provided with an internal thread, and the outer wall of the machine body is provided with an external thread matched with the internal thread.
The beneficial effects of the invention are as follows:
1. The outer wall of the machine body is connected with the inner thread of the inner wall of the shell through the outer thread, and the scale marks of the force value are marked on the outer wall of the machine body, so that the machine body can control the feeding amount to the inside of the shell through the threads, the displacement stroke of the sliding block can be changed, and the force of the ejector rod pressing the microneedle patch is changed;
2. The electromagnet can be fixed when being electrified, the electromagnet can lose electromagnetic force when being powered off, the slider can be impacted downwards along the chute inside the shell under the action of gravity, kinetic energy obtained by the gravity is transferred to the tail part of the ejector rod, and the tail part of the ejector rod compresses the spring to move towards the outside of the pressure head, so that the elastic gasket at the head part of the ejector rod can press the microneedle patch into the skin surface, the skin radian can be adapted, and manual needle insertion is avoided.
Drawings
Fig. 1 is a cross-sectional view of the present invention prior to use.
Fig. 2 is a cross-sectional view of the invention in use.
Fig. 3 is a cross-sectional view of the present invention after use.
Fig. 4 is an exploded view of the present invention.
Detailed Description
The following description of the patent application will be made more complete and should be apparent to those skilled in the art that the embodiments described are some but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be noted that, as the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," "outer," and the like are used for convenience in describing the present invention and simplifying the description based on the azimuth or positional relationship shown in the drawings, it should not be construed as limiting the present invention, but rather should indicate or imply that the devices or elements referred to must have a specific azimuth, be constructed and operated in a specific azimuth. Furthermore, the terms "first," "second," "third," and the like, as used herein, are used for descriptive purposes only and are not to be construed as indicating or implying any relative importance.
In the description of the present invention, it should be noted that unless explicitly stated and limited otherwise, the terms "mounted," "connected," and "connected" should be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Referring to the drawings, a microneedle injector based on gravity loading comprises a vertical shell 12 with a hollow inner cavity, wherein the vertical shell 12 is cylindrical in whole; the upper end of the vertical shell 12 is in threaded connection with a machine body 5 which can be screwed in or out relative to the vertical shell 12, and the inner cavity of the machine body 5 is communicated with the inner cavity of the vertical shell 12; the inner wall of the inner cavity of the vertical shell 12 is provided with an internal thread, and the outer wall of the machine body 5 is provided with an external thread matched with the internal thread.
The top of the machine body 5 is provided with a press switch 8, the outer side wall of the machine body 5 is provided with an indicator lamp 7, the inner cavity of the machine body 5 is provided with a power supply 9 and an electromagnet 6 which are arranged up and down, a magnetic coil 61 is wound around the electromagnet 6, and the power supply 9 is connected with the electromagnet 6, the indicator lamp 7 and the press switch 8 in series in sequence; when the push switch 8 is pushed, the electromagnet 6 is in an electrified state, and the indicator lamp 7 lights a green light; when the pressing switch 8 is pressed again, the electromagnet 6 is in a power-off state, the electromagnet 6 loses electromagnetic force, and the indicator lamp 7 is extinguished; the control circuit is electrically connected with the power supply 9 and the electric quantity indicator lamp 7 respectively, and when the electric quantity of the power supply 9 is insufficient or before full charge, the control circuit sends a red light lighting instruction to the electric quantity indicator lamp 7;
A sliding block 10 is slidably connected in the inner cavity of the vertical shell 12 and positioned below the machine body 5, and the sliding block 10 is a magnetic column body with a certain weight; four sliding grooves extending in the vertical direction are arranged on the inner wall of the inner cavity of the vertical shell 12 at intervals along the circumferential direction, the four sliding grooves are arranged on the internal threads of the inner wall of the inner cavity of the vertical shell 12 at intervals along the circumferential direction, the upper end and the lower end of each sliding groove extend to the top surface and the bottom surface of the shell 12 respectively, and the sliding grooves do not influence the engagement of the internal threads and the external threads; a groove is arranged on the outer wall of the sliding block 10 at a position corresponding to the sliding groove, and a roller 11 which is in sliding connection with the sliding groove is arranged in the groove;
The lower end of the vertical shell 12 is connected with a pressure head 1, the inner cavity of the pressure head 1 is provided with a diaphragm plate, and the center of the diaphragm plate is provided with a through hole; the diaphragm plate divides the inner cavity of the pressure head 1 into an upper cavity and a lower cavity, and the upper cavity of the pressure head 1 is communicated with the inner cavity of the shell 12; the upper cavity of the pressure head 1 is internally provided with a push rod tail 2, and the push rod tail 2 is circular plate-shaped; the center of the bottom surface of the ejector rod tail 2 is provided with a connecting rod, the connecting rod penetrates through a through hole of the diaphragm plate to extend into a lower cavity of the pressure head 1 and is connected with the ejector rod head 21, and a spring 4 is sleeved on the connecting rod and positioned between the upper surface of the diaphragm plate and the lower surface of the ejector rod tail 2; the ejector rod head 21 is in a circular plate shape, and the bottom surface of the ejector rod head 21 is provided with an elastic gasket 3 which can adapt to the skin contour and can press the microneedle patch into the skin; under the action of the elastic force of the spring 4, the ejector rod head 21 is often contracted in the lower cavity of the pressure head 1, and only when the ejector rod tail 2 receives enough external force, the ejector rod head 21 can move to the outside of the pressure head 1, so that the microneedle patch is pressed into the skin surface.
When the electromagnet 6 is electrified, magnetic force is generated to attract the sliding block 10 to lift upwards, the spring 4 is in a natural state, the tail 2 of the ejector rod is jacked up, and the head 21 of the ejector rod is contracted in the lower cavity of the pressure head 1; when the electromagnet 6 is powered off, the magnetic force disappears, the sliding block 10 moves downwards under the action of gravity and falls on the ejector rod tail 2, the ejector rod tail 2 is pressed down, the spring 4 is in a compressed state, and the ejector rod head 21 stretches out of the pressure head 1 to press the microneedle patch into the skin.
In this embodiment, the microneedle patch is attached to the target skin before use, and the feeding amount of the body 5 into the housing 12 is adjusted to a desired value;
When in use, the first step is: pressing down the push switch 8 to enable the electromagnet 6 to be electrified and fix the sliding block 10, at the moment, the indicator lamp 7 lights a green light, then the pressure head 1 is placed on the skin, and the microneedle patch is positioned in the center of the pressure head 1, and as the tail 2 of the ejector rod is acted by the spring 4, the head 21 of the ejector rod is contracted in the lower cavity of the pressure head 1, and at the moment, the microneedle patch is not stressed;
and secondly, after the pressure head 1 is contacted with the skin stably, the pressing switch 8 is pressed down again, at the moment, the electromagnet 6 is cut off to lose electromagnetic force, the sliding block 10 slides downwards along the sliding groove in the shell 12 by virtue of the roller 11 under the action of gravity, kinetic energy generated by gravity is transferred to the ejector rod tail 2, the ejector rod tail 2 compresses the spring 4 and transfers the kinetic energy to the ejector rod head 21, at the moment, the ejector rod head 21 moves to the outside of the pressure head 1, and the elastic gasket 3 is used for attaching the skin contour and pressing the microneedle patch into the skin surface.
If the physical properties of the skin change, the force required to insert the microneedle patch will also change. In order to adapt to the skins with different physical properties, the displacement stroke of the sliding block 10 can be changed by adjusting the feeding amount of the machine body 5 to the inside of the shell 12, so that the effect of changing the needle inserting force of the ejector rod head 21 is achieved.
If the microneedle device is used, the machine body 5 can be completely contracted into the shell 12, so that the effects of protecting the machine body 5 and saving space can be achieved.
The embodiments described in the present specification are merely examples of implementation forms of the inventive concept, and the scope of protection of the present invention should not be construed as being limited to the specific forms set forth in the embodiments, and the scope of protection of the present invention and equivalent technical means that can be conceived by those skilled in the art based on the inventive concept.
Claims (3)
1. A microneedle injector based on gravity loading, characterized in that: the device comprises a vertical shell (12) with a hollow inner cavity, wherein the upper end of the vertical shell (12) is in threaded connection with a machine body (5) which can be screwed in or out relative to the vertical shell (12), and the inner cavity of the machine body (5) is communicated with the inner cavity of the vertical shell (12); the top of the machine body (5) is provided with a push switch (8), the outer side wall of the machine body (5) is provided with an indicator lamp (7), the inner cavity of the machine body (5) is provided with a power supply (9) and an electromagnet (6) which are arranged up and down, a magnetic coil (61) is wound around the electromagnet (6), and the power supply (9) is sequentially connected with the electromagnet (6), the indicator lamp (7) and the push switch (8) in series;
A sliding block (10) with a certain weight is connected in the inner cavity of the vertical shell (12) and positioned below the machine body (5) in a sliding way, and the sliding block (10) is made of a magnetic material; the inner wall of the inner cavity of the vertical shell (12) is provided with a plurality of sliding grooves extending along the vertical direction at intervals along the circumferential direction, the outer wall of the sliding block (10) is provided with a groove at the position corresponding to the sliding groove, and a roller (11) in sliding connection with the sliding groove is arranged in the groove;
The lower end of the vertical shell (12) is connected with a pressure head (1), the inner cavity of the pressure head (1) is provided with a diaphragm, and the center of the diaphragm is provided with a through hole; the diaphragm plate divides the inner cavity of the pressure head (1) into an upper cavity and a lower cavity, and the upper cavity of the pressure head (1) is communicated with the inner cavity of the shell (12); a push rod tail (2) is arranged in the upper cavity of the pressure head (1), and the push rod tail (2) is in a circular plate shape; the center of the bottom surface of the ejector rod tail part (2) is provided with a connecting rod, the connecting rod penetrates through a through hole of the diaphragm plate to extend into a lower cavity of the pressure head (1) and is connected with the ejector rod head (21), and a spring (4) is sleeved on the connecting rod and positioned between the upper surface of the diaphragm plate and the lower surface of the ejector rod tail part (2); the ejector rod head (21) is in a circular plate shape, the elastic gasket (3) is arranged on the bottom surface of the ejector rod head (21), and the elastic gasket (3) has elasticity and can adapt to the skin contour and press the microneedle patch into the skin;
When the electromagnet (6) is electrified, magnetic force is generated to attract the sliding block (10) to lift upwards, the spring (4) is in a natural state, the tail part (2) of the ejector rod is jacked, and the head part (21) of the ejector rod is contracted in the lower cavity of the pressure head (1); when the electromagnet (6) is powered off, the magnetic force disappears, the sliding block (10) moves downwards under the action of gravity and falls on the ejector rod tail (2), the ejector rod tail (2) is pressed down, the spring (4) is in a compressed state, and the ejector rod head (21) stretches out of the pressure head (1) to press the microneedle patch into the skin.
2. A gravity-based microneedle injector according to claim 1, wherein: the number of the sliding grooves is four, the four sliding grooves are arranged on the inner wall of the inner cavity of the vertical shell (12) at intervals along the circumferential direction, and the upper end and the lower end of each sliding groove extend to the top surface and the bottom surface of the shell (12) respectively.
3. A gravity-based microneedle injector according to claim 1, wherein: the inner wall of the inner cavity of the vertical shell (12) is provided with an internal thread, and the outer wall of the machine body (5) is provided with an external thread matched with the internal thread.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210410016.4A CN114796839B (en) | 2022-04-19 | 2022-04-19 | Microneedle needle insertion device based on gravity loading |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210410016.4A CN114796839B (en) | 2022-04-19 | 2022-04-19 | Microneedle needle insertion device based on gravity loading |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114796839A CN114796839A (en) | 2022-07-29 |
| CN114796839B true CN114796839B (en) | 2024-05-03 |
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ID=82506014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210410016.4A Active CN114796839B (en) | 2022-04-19 | 2022-04-19 | Microneedle needle insertion device based on gravity loading |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114796839B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011078711A (en) * | 2009-10-05 | 2011-04-21 | Kosumedei Seiyaku Kk | Microneedle array administration device using magnetic repulsion |
| CN103654949A (en) * | 2013-12-26 | 2014-03-26 | 重庆德马光电技术有限公司 | Radio frequency micro-needle therapeutic equipment |
| CN104955517A (en) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | Applicator |
| CN109432585A (en) * | 2018-11-08 | 2019-03-08 | 中科微针（北京）科技有限公司 | Microneedle transdermal delivery needle inserter |
| CN215231575U (en) * | 2021-07-01 | 2021-12-21 | 柔电芯云(珠海)科技有限公司 | Microneedle patch leading-in device |
| CN215309660U (en) * | 2021-04-21 | 2021-12-28 | 广东思敏医疗器械科技有限公司 | Microneedle puncture device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2654582B1 (en) * | 2010-12-22 | 2017-05-31 | Valeritas, Inc. | Microneedle patch applicator |
-
2022
- 2022-04-19 CN CN202210410016.4A patent/CN114796839B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011078711A (en) * | 2009-10-05 | 2011-04-21 | Kosumedei Seiyaku Kk | Microneedle array administration device using magnetic repulsion |
| CN104955517A (en) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | Applicator |
| CN103654949A (en) * | 2013-12-26 | 2014-03-26 | 重庆德马光电技术有限公司 | Radio frequency micro-needle therapeutic equipment |
| CN109432585A (en) * | 2018-11-08 | 2019-03-08 | 中科微针（北京）科技有限公司 | Microneedle transdermal delivery needle inserter |
| CN215309660U (en) * | 2021-04-21 | 2021-12-28 | 广东思敏医疗器械科技有限公司 | Microneedle puncture device |
| CN215231575U (en) * | 2021-07-01 | 2021-12-21 | 柔电芯云(珠海)科技有限公司 | Microneedle patch leading-in device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114796839A (en) | 2022-07-29 |
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