CN114796839A - Microneedle insertion device based on gravity loading - Google Patents
Microneedle insertion device based on gravity loading Download PDFInfo
- Publication number
- CN114796839A CN114796839A CN202210410016.4A CN202210410016A CN114796839A CN 114796839 A CN114796839 A CN 114796839A CN 202210410016 A CN202210410016 A CN 202210410016A CN 114796839 A CN114796839 A CN 114796839A
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- CN
- China
- Prior art keywords
- inner cavity
- ejector rod
- pressure head
- machine body
- cavity
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 230000005484 gravity Effects 0.000 title claims abstract description 15
- 230000037431 insertion Effects 0.000 title abstract description 5
- 238000003780 insertion Methods 0.000 title abstract description 5
- 238000005192 partition Methods 0.000 claims abstract description 12
- 239000000696 magnetic material Substances 0.000 claims description 2
- 238000005096 rolling process Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 238000013271 transdermal drug delivery Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
Abstract
A microneedle feeder based on gravity loading comprises a vertical shell with a hollow inner cavity, wherein the upper end of the vertical shell is in threaded connection with a machine body which can be screwed in or out relative to the vertical shell, and the inner cavity of the machine body is communicated with the inner cavity of the vertical shell; the top of the machine body is provided with a press switch, and the inner cavity of the machine body is provided with a power supply and an electromagnet which are arranged up and down; a magnetic slider is slidably connected in the inner cavity of the vertical shell and below the machine body, a pressure head is connected to the lower end of the vertical shell, a transverse partition plate is arranged in the inner cavity of the pressure head, the transverse partition plate divides the inner cavity of the pressure head into an upper cavity and a lower cavity, and the upper cavity of the pressure head is communicated with the inner cavity of the shell; the inner of the upper cavity of the pressure head is provided with a push rod tail part, the push rod tail part is provided with a connecting rod which downwards penetrates through the through hole, the connecting rod is connected with the head part of the push rod, and the bottom surface of the head part of the push rod is provided with an elastic gasket which can be attached to the contour of the skin and can press the microneedle patch into the skin. The invention has controllable force, can adapt to skin radian, and can avoid manual needle insertion.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a microneedle feeder based on gravity loading.
Background
The microneedle has a fine size and can be used for transdermal administration without touching subcutaneous nerves, so that the microneedle can achieve painless transdermal administration. Microneedle patches are often used as painless transdermal delivery vehicles in order to deliver a sufficient amount of drug to the skin.
The microneedles are generally distributed on the microneedle patch in a certain manner, and the microneedles are fine in size, so that the microneedle patch needs to penetrate into the skin with certain force and speed, otherwise, the microneedles on the microneedle patch are easy to break or bend, which affects the transdermal drug delivery effect of the microneedle patch.
Although the needle inserting force and time of the existing microneedle needle inserter are controllable, the existing microneedle needle inserter mainly adopts a manual needle inserting mode, and almost does not consider the influence of uneven stress of a microneedle patch caused by skin radian and contour. Therefore, a microneedle feeder which has controllable strength, can adapt to the radian of skin and can avoid manual needle insertion is needed to be developed.
Disclosure of Invention
In order to overcome the problems, the invention provides a microneedle feeder based on gravity loading.
The technical scheme adopted by the invention is as follows: a microneedle feeder based on gravity loading comprises a vertical shell with a hollow inner cavity, wherein the upper end of the vertical shell is in threaded connection with a machine body which can be screwed in or out relative to the vertical shell, and the inner cavity of the machine body is communicated with the inner cavity of the vertical shell; the top of the machine body is provided with a press switch, the outer side wall of the machine body is provided with an indicator light, the inner cavity of the machine body is provided with a power supply and an electromagnet which are arranged up and down, a magnetic coil is wound around the electromagnet, and the power supply is sequentially connected with the electromagnet, the indicator light and the press switch in series;
a sliding block with a certain weight is connected in the inner cavity of the vertical shell and is positioned below the machine body in a sliding manner, and the sliding block is made of a magnetic material; a plurality of sliding grooves extending in the vertical direction are formed in the inner wall of the inner cavity of the vertical shell at intervals along the circumferential direction, grooves are formed in the positions, corresponding to the sliding grooves, of the outer wall of the sliding block, and rolling wheels connected with the sliding grooves in a sliding mode are arranged in the grooves;
the lower end of the vertical shell is connected with a pressure head, a transverse partition plate is arranged in an inner cavity of the pressure head, and a through hole is formed in the center of the transverse partition plate; the diaphragm plate divides the inner cavity of the pressure head into an upper cavity and a lower cavity, and the upper cavity of the pressure head is communicated with the inner cavity of the shell; the tail part of the ejector rod is arranged in the upper cavity of the pressure head and is in a circular plate shape; a connecting rod is arranged in the center of the bottom surface of the tail part of the ejector rod, penetrates through the through hole of the transverse partition plate, extends into the lower cavity of the pressure head and is connected with the head part of the ejector rod, and a spring is sleeved on the connecting rod and positioned between the upper surface of the transverse partition plate and the lower surface of the tail part of the ejector rod; the head of the ejector rod is in a circular plate shape, the bottom surface of the head of the ejector rod is provided with an elastic gasket, the elastic gasket has elasticity, and the elastic gasket can adapt to the contour of skin and press the microneedle patch into the skin;
when the electromagnet is electrified, magnetic force is generated to attract the sliding block to lift upwards, the spring is in a natural state at the moment, the tail part of the ejector rod is jacked up, and the head part of the ejector rod is contracted in the lower cavity of the pressure head; when the electromagnet is powered off, the magnetic force disappears, the sliding block moves downwards under the action of gravity and falls on the tail part of the ejector rod, the tail part of the ejector rod is pressed down, the spring is in a compression state, and the head part of the ejector rod extends out of the pressure head to press the microneedle patch into the skin.
Further, the quantity of spout is four, and four spouts set up at the inner chamber inner wall of vertical casing along circumference interval, and the upper and lower both ends of spout extend to the top surface and the bottom surface of casing respectively.
Furthermore, the inner wall of the inner cavity of the vertical shell is provided with an internal thread, and the outer wall of the machine body is provided with an external thread matched with the internal thread.
The invention has the beneficial effects that:
1. the outer wall of the body is connected with the inner thread of the inner wall of the shell through an external thread, and scale marks of force values are marked on the outer wall of the body, so that the body can control the feeding amount to the inside of the shell through the thread, the displacement stroke of the sliding block can be changed, and the force of the ejector rod pressing the microneedle patch is changed;
2. the electromagnet can fix the sliding block when being powered on, the electromagnet loses electromagnetic force when being powered off, the sliding block is impacted downwards along the sliding groove in the shell under the action of gravity, kinetic energy obtained by the gravity is transmitted to the tail part of the ejector rod, the tail part of the ejector rod compresses the spring to move towards the outside of the pressure head, and therefore the elastic gasket at the head part of the ejector rod presses the microneedle patch into the surface of the skin, the skin radian is adapted, and manual needle insertion is avoided.
Drawings
Fig. 1 is a cross-sectional view of the present invention before use.
Fig. 2 is a cross-sectional view of the present invention in use.
Fig. 3 is a cross-sectional view of the present invention after use.
Fig. 4 is an exploded view of the present invention.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the orientations or positional relationships indicated as the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., appear based on the orientations or positional relationships shown in the drawings only for the convenience of describing the present invention and simplifying the description, but not for indicating or implying that the referred devices or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" as appearing herein are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" should be interpreted broadly, e.g., as being fixed or detachable or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to the drawings, a microneedle needle inserter based on gravity loading comprises a vertical shell 12 with a hollow inner cavity, wherein the vertical shell 12 is cylindrical as a whole; the upper end of the vertical shell 12 is in threaded connection with a machine body 5 which can be screwed in or out relative to the vertical shell 12, and the inner cavity of the machine body 5 is communicated with the inner cavity of the vertical shell 12; the inner wall of the inner cavity of the vertical shell 12 is provided with an internal thread, and the outer wall of the machine body 5 is provided with an external thread matched with the internal thread.
The top of the machine body 5 is provided with a press switch 8, the outer side wall of the machine body 5 is provided with an indicator light 7, the inner cavity of the machine body 5 is provided with a power supply 9 and an electromagnet 6 which are arranged up and down, a magnetic coil 61 is wound around the electromagnet 6, and the power supply 9 is sequentially connected with the electromagnet 6, the indicator light 7 and the press switch 8 in series; when the push switch 8 is pressed, the electromagnet 6 is in a power-on state, and the indicator light 7 is turned on; when the push switch 8 is pressed again, the electromagnet 6 is in a power-off state, at the moment, the electromagnet 6 loses the electromagnetic force, and the indicator light 7 is also turned off; the power supply control circuit is characterized by further comprising a control circuit and an electric quantity indicator light 7, wherein the control circuit is respectively electrically connected with a power supply 9 and the electric quantity indicator light 7, and when the electric quantity of the power supply 9 is insufficient or before the power supply is fully charged, the control circuit sends a red light lighting instruction to the electric quantity indicator light 7;
a sliding block 10 is connected in the inner cavity of the vertical shell 12 and below the machine body 5 in a sliding manner, and the sliding block 10 is a magnetic cylinder with a certain weight; the inner wall of the inner cavity of the vertical shell 12 is circumferentially provided with four sliding grooves extending in the vertical direction at intervals, the four sliding grooves are circumferentially arranged on the internal thread of the inner wall of the inner cavity of the vertical shell 12 at intervals, the upper end and the lower end of each sliding groove respectively extend to the top surface and the bottom surface of the shell 12, and the sliding grooves do not influence the meshing of the internal thread and the external thread; a groove is arranged at the position of the outer wall of the sliding block 10 corresponding to the sliding chute, and a roller 11 which is connected with the sliding chute in a sliding way is arranged in the groove;
the lower end of the vertical shell 12 is connected with a pressure head 1, the inner cavity of the pressure head 1 is provided with a transverse partition plate, and the center of the transverse partition plate is provided with a through hole; the diaphragm plate divides the inner cavity of the pressure head 1 into an upper cavity and a lower cavity, and the upper cavity of the pressure head 1 is communicated with the inner cavity of the shell 12; the upper cavity of the pressure head 1 is internally provided with a mandril tail part 2, and the mandril tail part 2 is in a circular plate shape; a connecting rod is arranged in the center of the bottom surface of the tail part 2 of the ejector rod, penetrates through a through hole of the diaphragm plate, extends into the lower cavity of the pressure head 1 and is connected with the head part 21 of the ejector rod, and a spring 4 is sleeved on the connecting rod and positioned between the upper surface of the diaphragm plate and the lower surface of the tail part 2 of the ejector rod; the ejector rod head 21 is in a disc shape, and the bottom surface of the ejector rod head 21 is provided with an elastic gasket 3 which can adapt to the contour of the skin and can press the microneedle patch into the skin; under the action of the elastic force of the spring 4, the head 21 of the ejector rod is always contracted in the lower cavity of the pressure head 1, and only when the tail 2 of the ejector rod is subjected to a large enough external force, the head 21 of the ejector rod can move to the outside of the pressure head 1, so that the microneedle patch is pressed into the skin surface.
When the electromagnet 6 is electrified, magnetic force is generated to attract the sliding block 10 to lift upwards, the spring 4 is in a natural state at the moment, the tail part 2 of the ejector rod is jacked up, and the head part 21 of the ejector rod is contracted in the lower cavity of the pressure head 1; when the electromagnet 6 is powered off, the magnetic force disappears, the sliding block 10 moves downwards under the action of gravity and falls on the tail part 2 of the ejector rod, the tail part 2 of the ejector rod is pressed downwards, the spring 4 is in a compressed state, and the head part 21 of the ejector rod extends out of the pressure head 1 to press the microneedle patch into the skin.
In this embodiment, before use, the microneedle patch is attached to the target skin, and the feeding amount of the body 5 into the housing 12 is adjusted to a desired value;
in use, the first step: pressing the press switch 8 to electrify the electromagnet 6 to fix the slide block 10, lighting the indicator light 7 at the moment, then placing the pressure head 1 on the skin, and enabling the microneedle patch to be positioned at the center of the pressure head 1, wherein the tail part 2 of the ejector rod is acted by the spring 4, the head part 21 of the ejector rod is contracted in the lower cavity of the pressure head 1, and the microneedle patch is not stressed at the moment;
the second step, treat that pressure head 1 and skin contact are stable after, press down push switch 8 once more, electro-magnet 6 is lost the electromagnetic force by the cut-off power supply this moment, slider 10 relies on gyro wheel 11 along the inside spout lapse of casing 12 because of the action of gravity, will be given ejector pin afterbody 2 by the kinetic energy transmission that gravity produced, ejector pin afterbody 2 then compression spring 4 and give ejector pin head 21 with kinetic energy transmission, ejector pin head 21 moves to the outside of pressure head 1 this moment, rely on 3 laminating skin contours of elastic gasket and impress the microneedle paster into the skin surface.
If the physical properties of the skin change, the force required to insert the microneedle patch into the needle also changes. In order to adapt to the skin with different physical properties, the displacement stroke of the slide block 10 can be changed by adjusting the feeding amount of the machine body 5 to the inside of the shell 12, so that the effect of changing the needle inserting force of the ejector rod head 21 is achieved.
If the microneedle needle inserter is used up, the body 5 can be completely retracted into the shell 12, so that the effects of protecting the body 5 and saving space can be achieved.
The embodiments described in this specification are merely illustrative of implementations of the inventive concept and the scope of the present invention should not be considered limited to the specific forms set forth in the embodiments but rather by the equivalents thereof as may occur to those skilled in the art upon consideration of the present inventive concept.
Claims (3)
1. A microneedle needle inserter based on gravity loading is characterized in that: the device comprises a vertical shell (12) with a hollow inner cavity, wherein the upper end of the vertical shell (12) is in threaded connection with a machine body (5) which can be screwed in or out relative to the vertical shell (12), and the inner cavity of the machine body (5) is communicated with the inner cavity of the vertical shell (12); the top of the machine body (5) is provided with a press switch (8), the outer side wall of the machine body (5) is provided with an indicator light (7), the inner cavity of the machine body (5) is provided with a power supply (9) and an electromagnet (6) which are arranged up and down, a magnetic coil (61) is wound around the electromagnet (6), and the power supply (9) is sequentially connected with the electromagnet (6), the indicator light (7) and the press switch (8) in series;
a sliding block (10) with a certain weight is connected in the inner cavity of the vertical shell (12) and is positioned below the machine body (5) in a sliding manner, and the sliding block (10) is made of a magnetic material; a plurality of sliding grooves extending in the vertical direction are formed in the inner wall of the inner cavity of the vertical shell (12) at intervals along the circumferential direction, grooves are formed in the positions, corresponding to the sliding grooves, of the outer wall of the sliding block (10), and rolling wheels (11) connected with the sliding grooves in a sliding mode are arranged in the grooves;
the lower end of the vertical shell (12) is connected with a pressure head (1), a transverse partition plate is arranged in an inner cavity of the pressure head (1), and a through hole is formed in the center of the transverse partition plate; the transverse clapboard divides the inner cavity of the pressure head (1) into an upper cavity and a lower cavity, and the upper cavity of the pressure head (1) is communicated with the inner cavity of the shell (12); an ejector rod tail part (2) is arranged in an upper cavity of the pressure head (1), and the ejector rod tail part (2) is in a circular plate shape; a connecting rod is arranged in the center of the bottom surface of the tail part (2) of the ejector rod, penetrates through the through hole of the transverse partition plate, extends into the lower cavity of the pressure head (1) and is connected with the head part (21) of the ejector rod, and a spring (4) is sleeved on the connecting rod and positioned between the upper surface of the transverse partition plate and the lower surface of the tail part (2) of the ejector rod; the ejector rod head (21) is in a disc shape, the bottom surface of the ejector rod head (21) is provided with an elastic gasket (3), and the elastic gasket (3) has elasticity and can adapt to the contour of the skin and press the microneedle patch into the skin;
the electromagnet (6) generates magnetic force when being electrified, the sliding block (10) is attracted to be lifted upwards, the spring (4) is in a natural state at the moment, the tail part (2) of the ejector rod is jacked up, and the head part (21) of the ejector rod is contracted in the lower cavity of the pressure head (1); when the electromagnet (6) is powered off, the magnetic force disappears, the sliding block (10) moves downwards under the action of gravity and falls on the tail part (2) of the ejector rod, the tail part (2) of the ejector rod is pressed downwards, the spring (4) is in a compressed state, and the head part (21) of the ejector rod extends out of the pressure head (1) to press the microneedle patch into the skin.
2. A gravity-loading-based microneedle needle inserter according to claim 1, wherein: the quantity of spout is four, and four spouts set up the inner chamber inner wall at vertical casing (12) along circumference interval, and the upper and lower both ends of spout extend to the top surface and the bottom surface of casing (12) respectively.
3. A gravity-loading based microneedle needle inserter according to claim 1, wherein: the inner wall of the inner cavity of the vertical shell (12) is provided with an internal thread, and the outer wall of the machine body (5) is provided with an external thread matched with the internal thread.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210410016.4A CN114796839B (en) | 2022-04-19 | Microneedle needle insertion device based on gravity loading |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210410016.4A CN114796839B (en) | 2022-04-19 | Microneedle needle insertion device based on gravity loading |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114796839A true CN114796839A (en) | 2022-07-29 |
| CN114796839B CN114796839B (en) | 2024-05-03 |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011078711A (en) * | 2009-10-05 | 2011-04-21 | Kosumedei Seiyaku Kk | Microneedle array administration device using magnetic repulsion |
| US20120184906A1 (en) * | 2010-12-22 | 2012-07-19 | Mcallister Devin V | Microneedle patch applicator |
| CN103654949A (en) * | 2013-12-26 | 2014-03-26 | 重庆德马光电技术有限公司 | Radio frequency micro-needle therapeutic equipment |
| CN104955517A (en) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | Applicator |
| CN109432585A (en) * | 2018-11-08 | 2019-03-08 | 中科微针（北京）科技有限公司 | Microneedle transdermal delivery needle inserter |
| CN215231575U (en) * | 2021-07-01 | 2021-12-21 | 柔电芯云(珠海)科技有限公司 | Microneedle patch leading-in device |
| CN215309660U (en) * | 2021-04-21 | 2021-12-28 | 广东思敏医疗器械科技有限公司 | Microneedle puncture device |
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011078711A (en) * | 2009-10-05 | 2011-04-21 | Kosumedei Seiyaku Kk | Microneedle array administration device using magnetic repulsion |
| US20120184906A1 (en) * | 2010-12-22 | 2012-07-19 | Mcallister Devin V | Microneedle patch applicator |
| CN104955517A (en) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | Applicator |
| CN103654949A (en) * | 2013-12-26 | 2014-03-26 | 重庆德马光电技术有限公司 | Radio frequency micro-needle therapeutic equipment |
| CN109432585A (en) * | 2018-11-08 | 2019-03-08 | 中科微针（北京）科技有限公司 | Microneedle transdermal delivery needle inserter |
| CN215309660U (en) * | 2021-04-21 | 2021-12-28 | 广东思敏医疗器械科技有限公司 | Microneedle puncture device |
| CN215231575U (en) * | 2021-07-01 | 2021-12-21 | 柔电芯云(珠海)科技有限公司 | Microneedle patch leading-in device |
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