CN114712250A - Crown and bridge repairing ceramic with efficient anti-deformation streptococcus and preparation and application thereof - Google Patents
Crown and bridge repairing ceramic with efficient anti-deformation streptococcus and preparation and application thereof Download PDFInfo
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- 239000000919 ceramic Substances 0.000 title claims abstract description 57
- 241000194017 Streptococcus Species 0.000 title claims abstract description 10
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims abstract description 72
- DNEHKUCSURWDGO-UHFFFAOYSA-N aluminum sodium Chemical compound [Na].[Al] DNEHKUCSURWDGO-UHFFFAOYSA-N 0.000 claims abstract description 47
- 239000011787 zinc oxide Substances 0.000 claims abstract description 36
- 238000000498 ball milling Methods 0.000 claims abstract description 21
- 239000000843 powder Substances 0.000 claims abstract description 19
- 241000194019 Streptococcus mutans Species 0.000 claims abstract description 17
- 238000001354 calcination Methods 0.000 claims abstract description 17
- 230000008439 repair process Effects 0.000 claims abstract description 17
- 239000000463 material Substances 0.000 claims abstract description 13
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000011230 binding agent Substances 0.000 claims abstract description 12
- 230000032683 aging Effects 0.000 claims abstract description 10
- 238000000465 moulding Methods 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 39
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 21
- 239000002131 composite material Substances 0.000 claims description 15
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 13
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 238000001035 drying Methods 0.000 claims description 9
- 238000000227 grinding Methods 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000004321 preservation Methods 0.000 claims description 7
- 238000007873 sieving Methods 0.000 claims description 7
- QPLDLSVMHZLSFG-UHFFFAOYSA-N Copper oxide Chemical compound [Cu]=O QPLDLSVMHZLSFG-UHFFFAOYSA-N 0.000 claims description 6
- 239000005751 Copper oxide Substances 0.000 claims description 6
- 229910000431 copper oxide Inorganic materials 0.000 claims description 6
- 238000003825 pressing Methods 0.000 claims description 4
- 238000009694 cold isostatic pressing Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000003389 potentiating effect Effects 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 16
- 230000008569 process Effects 0.000 abstract description 4
- 229940031008 streptococcus mutans Drugs 0.000 abstract description 3
- 239000000758 substrate Substances 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 5
- 238000000462 isostatic pressing Methods 0.000 description 5
- 239000002002 slurry Substances 0.000 description 5
- 235000012217 sodium aluminium silicate Nutrition 0.000 description 4
- 208000035143 Bacterial infection Diseases 0.000 description 3
- 229940115440 aluminum sodium silicate Drugs 0.000 description 3
- 208000022362 bacterial infectious disease Diseases 0.000 description 3
- 208000025157 Oral disease Diseases 0.000 description 2
- 208000002925 dental caries Diseases 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 208000030194 mouth disease Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 229910000503 Na-aluminosilicate Inorganic materials 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000000429 sodium aluminium silicate Substances 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
- C04B35/16—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on silicates other than clay
- C04B35/18—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on silicates other than clay rich in aluminium oxide
- C04B35/19—Alkali metal aluminosilicates, e.g. spodumene
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/20—Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/802—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
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- C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
- C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
- C04B2235/30—Constituents and secondary phases not being of a fibrous nature
- C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
- C04B2235/3281—Copper oxides, cuprates or oxide-forming salts thereof, e.g. CuO or Cu2O
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- C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
- C04B2235/3284—Zinc oxides, zincates, cadmium oxides, cadmiates, mercury oxides, mercurates or oxide forming salts thereof
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Abstract
The invention belongs to the technical field of crown and bridge repairing materials, and discloses crown and bridge repairing ceramic with efficient anti-deformation streptococcus, and preparation and application thereof. The method comprises the following steps: (1) carrying out ball milling on sodium aluminum silicate and nano zinc oxide to obtain sodium aluminum silicate powder doped with nano zinc oxide; by mass percentage, 97 to 99.5 percent of sodium aluminum silicate and 0.5 to 3 percent of nano zinc oxide; (2) and mixing the sodium aluminum silicate powder doped with the nano zinc oxide with a binder uniformly, aging, granulating, molding and calcining to obtain the efficient anti-streptococcus-mutans crown bridge repair ceramic. The crown bridge repairing ceramic with high-efficiency anti-streptococcus mutans has high-efficiency antibacterial efficiency on streptococcus mutans, and the added zinc oxide has no obvious hardness change on the sodium aluminum silicate ceramic substrate. The preparation method disclosed by the invention is simple in process, good in process controllability and high in repeatability, can be used for the crown and bridge repairing material, and has a relatively high popularization value.
Description
Technical Field
The invention belongs to the technical field of crown and bridge repairing materials, and particularly relates to a crown and bridge repairing ceramic with efficient anti-deformation streptococcus, and preparation and application thereof.
Background
Oral diseases, particularly dental caries and periodontal diseases are common frequently-occurring diseases and seriously affect the health of people. The crown bridge repairing material has made great progress with the continuous development, and the ceramic-based crown bridge repairing material and the forming technology have become a hot spot in recent ten years, wherein the sodium aluminum silicate ceramic is widely applied to the field of crown bridge repairing at present due to the matching of the mechanical property and the aesthetic property with natural teeth of a human body. However, the currently reported sodium aluminum silicate ceramics do not have antibacterial performance, and are easy to cause implantation failure due to bacterial infection in the early stage of implantation, so that the pain of a patient is further deepened, the time and the energy of the patient are wasted, and the treatment cost of the patient is increased. Streptococcus mutans is the largest proportion of the natural oral flora and has anaerobic properties, so that it is often aggregated to cause oral diseases such as dental caries. Therefore, the development of the sodium aluminosilicate ceramic with efficient anti-deformation streptococcus will greatly advance the field of crown bridge repair.
Disclosure of Invention
In order to overcome the defects and shortcomings in the prior art, the invention aims to provide a preparation method of high-efficiency anti-streptococcus-deformation sodium aluminum silicate/nano zinc oxide composite ceramic (namely, crown bridge repair ceramic with high-efficiency anti-streptococcus-deformation).
The invention also aims to provide the high-efficiency anti-streptococcus-mutans sodium aluminum silicate/nano zinc oxide composite ceramic (namely the crown bridge repair ceramic with high-efficiency anti-streptococcus-mutans) obtained by the preparation method. The material of the invention has obvious antibacterial effect.
The invention further aims to provide application of the high-efficiency anti-streptococcus aluminum sodium silicate/nano zinc oxide composite ceramic (namely the crown and bridge repair ceramic with the high-efficiency anti-streptococcus) in the field of crown and bridge repair.
The purpose of the invention is realized by the following technical scheme:
a preparation method of a crown bridge repairing ceramic with efficient anti-deformation streptococcus comprises the following steps:
(1) carrying out ball milling on sodium aluminum silicate and nano zinc oxide to obtain sodium aluminum silicate powder doped with nano zinc oxide; by mass percentage, 97 to 99.5 percent of sodium aluminum silicate and 0.5 to 3 percent of nano zinc oxide;
(2) mixing the sodium aluminum silicate powder doped with the nano zinc oxide with a binder uniformly, aging, granulating and molding to obtain molded sodium aluminum silicate/nano copper oxide;
(3) and calcining the formed sodium aluminum silicate/nano copper oxide to obtain the streptococcus mutans-resistant sodium aluminum silicate/nano copper oxide composite ceramic, namely the efficient streptococcus mutans-resistant crown and bridge repair ceramic.
In the step (1), absolute ethyl alcohol is added into sodium aluminum silicate and nano zinc oxide during ball milling; the ball milling time is 8-12h, and the ball milling speed is 300-450 rpm.
After ball milling, drying, grinding and sieving treatment are carried out.
The drying temperature is 40-75 ℃; the mesh number of the sieve is 60-100 meshes.
The dosage of the binder in the step (2) is 4-10% of the mass of the sodium aluminum silicate powder doped with the nano zinc oxide.
The binder consists of polyvinyl alcohol, glycerol and water; polyvinyl alcohol: glycerol: the mass ratio of water is (3-5): (1.5-2): 1.5: 30.
the aging time in the step (2) is 20-30 h.
The molding is to adopt a hand-pulling type press to perform primary pressing to form a blank body for molding, and then perform secondary pressing through cold isostatic pressing, wherein the pressure is 200-220 MPa; the molding time is 25-35 min.
The calcining conditions in the step (3) are as follows: the calcination temperature is 700 ℃ and 900 ℃, the heating rate is 5-10 ℃/min, and the heat preservation time is 2-4 h.
The efficient anti-deformation streptococcus aluminum sodium silicate/nano zinc oxide composite ceramic is prepared by the method.
The high-efficiency anti-deformation streptococcus aluminum sodium silicate/nano zinc oxide composite ceramic is used for a medical crown and bridge repairing material, in particular to a crown and bridge repairing material.
The invention utilizes the sodium aluminum silicate ceramic material as a good dental crown repair material. By introducing zinc oxide nano particles, under the condition of not generating excessive influence on the self physical and chemical properties of the sodium aluminum silicate ceramic, the nano zinc oxide is contacted with bacteria to destroy the bacterial membrane, so that intracellular substances of the bacteria flow out to kill the bacteria and destroy genetic factors by utilizing the ion release of the zinc oxide; in addition, the nano zinc oxide can kill bacteria by generating active oxygen. Therefore, the material can quickly and efficiently kill the specific streptococcus mutans in the oral cavity, thereby avoiding the repair failure caused by bacterial infection in the early repair stage of the crown bridge repair material.
Compared with the prior art, the invention has the following advantages and beneficial effects:
the preparation method of the invention has simple and convenient process; the process controllability is good, the repeatability is high, and the resources are saved; the ceramic provided by the invention can be used for quickly and efficiently killing streptococcus mutans, so that the repair failure caused by bacterial infection at the early stage of repair of the crown bridge repair material is avoided.
Drawings
FIG. 1 is a graph showing the antibacterial effect of sodium aluminum silicate (NAS) ceramics prepared in a comparative example on Streptococcus mutans;
FIG. 2 is a graph showing the antibacterial effect of 1 wt% ZnO-doped sodium aluminum silicate (NAS/1.0Zn) ceramic prepared in example 2 on Streptococcus mutans;
FIG. 3 is a graph showing the antibacterial effect of 3 wt% ZnO-doped sodium aluminum silicate (NAS/3.0Zn) ceramic prepared in example 4 on Streptococcus mutans;
FIG. 4 is a statistical chart of the count of the antibacterial plates of the ceramics prepared in comparative example, example 2 and example 4.
Detailed Description
The present invention will be described in further detail with reference to examples and drawings, but the embodiments of the present invention are not limited thereto.
Those who do not specify specific conditions in the examples of the present invention follow conventional conditions or conditions recommended by the manufacturer. The raw materials, reagents and the like which are not indicated for manufacturers are all conventional products which can be obtained by commercial purchase.
Comparative example
Performing ball milling on the sodium aluminum silicate powder for 8 hours (adding absolute ethyl alcohol when the ball milling is performed, wherein the mass ratio of the powder to the absolute ethyl alcohol is 1:1.3), rotating at the speed of 300rpm, drying the slurry at 40 ℃, and then adding a binder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water: 3:1.5:1.5:30) accounting for 4% of the mass of the powder; grinding and sieving again (100 mesh), aging at 25 deg.C for 24 hr, tabletting, and isostatic pressing at 200MPa for 30 min; and (3) calcining the obtained sodium aluminum silicate/nano zinc oxide sheet at high temperature to obtain the ceramic, wherein the calcining temperature is 700 ℃, the heating rate is 5 ℃/min, and the heat preservation time is 2 h. FIG. 1 is a graph showing the antibacterial effect of sodium aluminum silicate (NAS) ceramic on Streptococcus mutans.
Compared with the blank group, the number of bacteria in the sodium aluminum silicate ceramic obtained by the comparative example is not obviously reduced, which shows that the sodium aluminum silicate ceramic does not have good antibacterial performance.
Example 1
Ball-milling 99.5% of sodium aluminum silicate and 0.5% of nano zinc oxide for 9 hours (adding absolute ethyl alcohol during ball-milling, wherein the mass ratio of the composite powder to the absolute ethyl alcohol is 1:1.3), rotating at 350rpm, drying the slurry at 40 ℃, and adding a binder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water) with the mass ratio of 5% of the composite powder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water: 4:2:1.5: 30); grinding and sieving (100 mesh), aging at 25 deg.C for 24 hr, tabletting, and isostatic pressing at 200MPa for 30 min; and (3) calcining the obtained sodium aluminum silicate/nano zinc oxide sheet at high temperature to obtain the ceramic, wherein the calcining temperature is 750 ℃, the heating rate is 5 ℃/min, and the heat preservation time is 2.5 h.
Example 2
Ball-milling sodium aluminum silicate and nano zinc oxide according to the mass ratio of 99% to 1% for 10h (adding absolute ethyl alcohol during ball milling, wherein the mass ratio of the composite powder to the absolute ethyl alcohol is 1:1.3), rotating at 400rpm, drying the slurry at 40 ℃, and adding a binder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water) with the mass ratio of 6% of the composite powder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water is 4.5:2:1.5: 30); grinding and sieving (100 mesh), aging at 25 deg.C for 24 hr, tabletting, and isostatic pressing at 210MPa for 30 min; and (3) calcining the obtained sodium aluminum silicate/nano zinc oxide sheet at high temperature to obtain the ceramic, wherein the calcining temperature is 800 ℃, the heating rate is 7 ℃/min, and the heat preservation time is 3 h.
FIG. 2 is a graph showing the antibacterial effect of 1 wt% ZnO-doped sodium aluminum silicate (NAS/1.0Zn) ceramic prepared in example 2 on Streptococcus mutans.
The number of the NAS/1.0Zn ceramics obtained in the embodiment is obviously reduced compared with that of blank groups of bacteria, and the NAS/1.0Zn ceramics have certain antibacterial performance.
Example 3
Performing ball milling on sodium aluminum silicate and nano zinc oxide according to a mass ratio of 98% to 2% for 11 (adding absolute ethyl alcohol during ball milling, wherein the mass ratio of the composite powder to the absolute ethyl alcohol is 1:1.3) h, rotating at 450rpm, drying the slurry at 40 ℃, and adding a binder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water) accounting for 8% of the mass of the composite powder (the mass ratio of polyvinyl alcohol: glycerol: absolute ethyl alcohol: water is 5:2:1.5: 30); grinding and sieving (100 mesh), aging at 25 deg.C for 24 hr, tabletting, and isostatic pressing at 220MPa for 30 min; and (3) calcining the obtained sodium aluminum silicate/nano zinc oxide sheet at high temperature to obtain the ceramic, wherein the calcining temperature is 850 ℃, the heating rate is 8 ℃/min, and the heat preservation time is 3.5 h.
Example 4
Performing ball milling on sodium aluminum silicate and nano zinc oxide according to the mass ratio of 97% to 3% for 12 hours (adding absolute ethyl alcohol during ball milling, wherein the mass ratio of the composite powder to the absolute ethyl alcohol is 1:1.3), rotating at 450rpm, drying the slurry at 40 ℃, and adding a binder (polyvinyl alcohol: glycerol: absolute ethyl alcohol: water, wherein the mass ratio of the polyvinyl alcohol: glycerol: absolute ethyl alcohol: water is 5:2:1.5:30) accounting for 8% of the mass of the composite powder; grinding and sieving (100 mesh), aging at 25 deg.C for 24 hr, tabletting, and isostatic pressing at 220MPa for 30 min; and (3) calcining the obtained sodium aluminum silicate/nano zinc oxide sheet at high temperature to obtain the ceramic, wherein the calcining temperature is 800 ℃, the heating rate is 10 ℃/min, and the heat preservation time is 4 h.
FIG. 3 is a graph showing the antibacterial effect of sodium aluminum silicate (NAS/3.0Zn) ceramic doped with 3 wt% ZnO on Streptococcus mutans of example 4.
The NAS/3.0Zn ceramic obtained in the embodiment has a remarkably reduced number of bacteria compared with a blank group and kills all the bacteria, and shows that the NAS/3.0Zn ceramic has efficient antibacterial performance. Meanwhile, compared with the antibacterial effect of the NAS/1.0Zn ceramic on the streptococcus mutans of more than 80 percent, the NAS/3.0Zn ceramic has the antibacterial effect of 99 percent on the streptococcus mutans.
FIG. 4 is a statistical chart of the count of the antibacterial plates of the ceramics prepared in comparative example, example 2 and example 4.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (9)
1. A preparation method of a crown bridge repairing ceramic with efficient anti-deformation streptococcus is characterized by comprising the following steps: the method comprises the following steps:
(1) carrying out ball milling on sodium aluminum silicate and nano zinc oxide to obtain sodium aluminum silicate powder doped with nano zinc oxide; by mass percentage, 97 to 99.5 percent of sodium aluminum silicate and 0.5 to 3 percent of nano zinc oxide;
(2) mixing the sodium aluminum silicate powder doped with the nano zinc oxide with a binder uniformly, aging, granulating and molding to obtain molded sodium aluminum silicate/nano copper oxide;
(3) and calcining the formed sodium aluminum silicate/nano copper oxide to obtain the streptococcus mutans-resistant sodium aluminum silicate/nano copper oxide composite ceramic, namely the efficient streptococcus mutans-resistant crown and bridge repair ceramic.
2. The method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 1, wherein: the calcining conditions in the step (3) are as follows: the calcination temperature is 700 ℃ and 900 ℃, the heating rate is 5-10 ℃/min, and the heat preservation time is 2-4 h.
3. The method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 1, wherein:
the dosage of the binder in the step (2) is 4-10% of the mass of the sodium aluminum silicate powder doped with the nano zinc oxide;
the binder consists of polyvinyl alcohol, glycerol and water; polyvinyl alcohol: glycerol: the mass ratio of water is (3-5): (1.5-2): 1.5: 30.
4. the method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 1, wherein: in the step (1), absolute ethyl alcohol is added into sodium aluminum silicate and nano zinc oxide during ball milling; the ball milling time is 8-12h, and the ball milling speed is 300-450 rpm.
5. The method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 1, wherein: after ball milling, drying, grinding and sieving treatment are carried out.
6. The method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 5, wherein: the drying temperature is 40-75 ℃; the mesh number of the sieve is 60-100 meshes.
7. The method for preparing the crown bridge repairing ceramic with the highly efficient anti-streptococcus mutans according to claim 1, wherein: the aging time in the step (2) is 20-30 h;
the molding is to adopt a hand-pulling type press to perform primary pressing to form a blank body for molding, and then perform secondary pressing through cold isostatic pressing, wherein the pressure is 200-220 MPa; the molding time is 25-35 min.
8. A crown bridge repair ceramic having high-potency streptococcus mutans resistance obtained by the production method according to any one of claims 1 to 7.
9. The use of the crown-bridge repair ceramic with highly potent anti-streptococcus mutans according to claim 8, wherein: the crown and bridge repairing ceramic with the efficient anti-deformation streptococcus is used for preparing a crown and bridge repairing material.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115894001A (en) * | 2023-03-10 | 2023-04-04 | 湖南康纳新材料有限公司 | High-hardness wear-resistant resin-permeable ceramic composite material and preparation method and application thereof |
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| CN107721420A (en) * | 2017-09-06 | 2018-02-23 | 华南理工大学 | A kind of cupric oxide doped potassium-sodium niobate antibacterial piezoelectric ceramics implant and its preparation and application |
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Application publication date: 20220708 |