CN1146893A - Use in combination of alpha-hydroxy acid and titanium oxide for lightening skin - Google Patents
Use in combination of alpha-hydroxy acid and titanium oxide for lightening skin Download PDFInfo
- Publication number
- CN1146893A CN1146893A CN96111043A CN96111043A CN1146893A CN 1146893 A CN1146893 A CN 1146893A CN 96111043 A CN96111043 A CN 96111043A CN 96111043 A CN96111043 A CN 96111043A CN 1146893 A CN1146893 A CN 1146893A
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- Prior art keywords
- alpha
- acid
- hydroxy
- compositions
- titanium oxide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/068—Microemulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to the use of combination of at least one alpha-hydroxy acid and at least one titanium oxide for skin whitening.
Description
The present invention relates to 'alpha '-hydroxy acids and cooperate with titanium oxide and be used in or be used to prepare make-up composition or dermatological compositions, by this compositions part is coated on facial skin and/or the body skin, its purpose is to make skin pure white.This compositions can be nursing product or cosmetics.
Often, skin coloured or even very the dark colour people all wish to make skin show brilliance, use make-up composition or the dermatological compositions contain brightening agent for this purpose.
Using maximum materials as brightening agent is hydroquinone and derivant thereof, and their ether especially is as hydroquinone monomethyl ether and hydroquinone list ether, particularly kojic acid.
Hydroquinone and derivant thereof although they have some effect, because their toxicity has some side effect, make its use become very thorny unfortunately like this, or even dangerous.So, in addition also restriction to use hydroquinone concentration be 2%, hydroquinone is a kind of melanocyte to be had zest and Cytotoxic chemical compound especially, people expect to replace it whole or in part with many other chemical compounds.
Hydroquinone can be used with hydroxy acid.Therefore, file EP-A-273202 has described the effect of improving topical remedy's activating agent by the hydroxy acid that adds effective dose.List the activating agent of hydroquinone as the treatment senile plaque.But this cooperation has and uses the relevant defective of hydroquinone.
In addition, the defective that kojic acid and derivant thereof have is the cost height since this former thereby can not in " grand public " product, use heavy dose of, i.e. all uses.
Known other brightening agent.The US-A-5262153 patent document has illustrated that use lactic acid and salt thereof are used for skin whitening.But, it is believed that it is inadequate brightening the effect that is reached.
Therefore, also need nontoxic and effective brightening agent reasonable price, and this brightening agent can prepare " grand public " effectively Lightening compositions.
So content of the present invention is about when preparing cosmetic and/or dermatological compositions and/or be used for preparation cosmetic and/or dermatological compositions, and at least a 'alpha '-hydroxy acids and at least a titanium oxide are cooperated as skin whitener.
Coordination compound required for protection is made of existing product salable on the market, can access the Lightening compositions of various packings.In addition, the applicant is surprised to find, and coordination compound required for protection has the sure ability that brightens, this ability of brightening with use such as the prepared product of the more expensive product of kojic acid and so on close.
Really, by the JP-A-57-123824 file as can be known, but use the titanium dioxide skin whitening, also do not propose it is cooperated with 'alpha '-hydroxy acids, brighten so that reach effectively with rational cost but this file is both open.
In addition, the CH-684739 file description a kind of compositions that makes skin clean, this compositions contains flavonoid and the ascorbic acid that is fit form, this compositions also may contain the sunscreen just like titanium dioxide and so on.However, this part file is open is used as brightening agent with titanium dioxide and 'alpha '-hydroxy acids coordination compound.
The 'alpha '-hydroxy acids that the present invention uses can be saturated or undersaturated, straight chain, branching or cyclic.The hydrogen atom of carbochain can also be replaced by halogen, the halogeno-group with 2-28 carbon atom, alkyl, acyl group, acidic group, alkoxyl, carbonyl or alkoxyl.
The spendable 'alpha '-hydroxy acids of the present invention can be made of monocarboxylic acid or polybasic carboxylic acid, and these carboxylic acids have one or more hydroxyl-functionals, and wherein at least one is in the α position of described acid in these hydroxyl-functionals.
Preferably, 'alpha '-hydroxy acids of the present invention is the Alpha-hydroxy alkanoic acid with 2-18 carbon atom.
As the spendable 'alpha '-hydroxy acids of the present invention, can enumerate particularly that glycolic (or Alpha-hydroxy acetic acid), lactic acid (or α-Qiang Jibingsuan), maleic acid (or hydroxyl succinic acid), tartaric acid (or dyhydrobutanedioic acid), citric acid, mandelic acid, Alpha-hydroxy are sad, Alpha-hydroxy caproic acid, Alpha-hydroxy capric acid, Alpha-hydroxy dodecylic acid, Alpha-hydroxy tetradecanoic acid, Alpha-hydroxy hexadecanoic acid, Alpha-hydroxy octadecanoid acid, Alpha-hydroxy arachic acid, Alpha-hydroxy behenic acid, Alpha-hydroxy hexacosoic acid, Alpha-hydroxy octocosoic acid.
Preferably use lactic acid, glycolic, citric acid and/or tartaric acid according to the present invention.
These acid can be free acid form and/or be the form of a kind of salt in their the cooperation salt or be their ester or a kind of form in their corresponding amide in this compositions, perhaps may be corresponding lactide form (form that is obtained by the molecule autoemulsification).
Can prepare described salt by known method, for example with in the suitable alkali of sodium hydroxide, potassium hydroxide or ammonium hydroxide and so on and 'alpha '-hydroxy acids, or with organic base as triethanol ammonium and so on, or in the aminoacid (lysine, arginine) and 'alpha '-hydroxy acids.
When using the Alpha-hydroxy acid esters, can relate to methyl ester, ethyl ester, propyl ester, butyl ester, pentyl ester, own ester, monooctyl ester particularly.
In order to obtain gratifying whitening effect, it is 2.5-6 that compositions of the present invention preferably has last pH.
The amount of 'alpha '-hydroxy acids used according to the present invention, preferably 0.01-50% (weight) more preferably is 0.5-20% (weight), preferably 2-10% (weight).
According to the present invention, as titanium oxide, can use titanium dioxide particularly, surface treated titanium dioxide former state or possible, described titanium dioxide is pigment or ultramicro-pigment form.The granule mean size that is the pigment of ultra micro form for example is 5-100nm.
Untreated titanium oxide for example can be by TAYCA company with trade name " Micro-titanium Dioxide MT 500 B " or " Microtitanium DioxideMT 600 B " product sold, or by Tioxide company with trade name " SelectedTioxide A-HRC " product sold.
The surface-treated titanium oxide for example can be the oxide through following processing:
-silicon dioxide and aluminium oxide, as by TAYCA company with trade name " Micro-titanium Dioxide MT 100 SA " product sold, or by TIOXIDE company with trade name " Tioveil Fin ", " Tioveil OP ", " TioveilMOTG " and " Tioveil IPM " product sold
-aluminium oxide and aluminium stearate, as the product " Micro-titanium Dioxide MT 100 T " of TAYCA company,
-aluminium oxide and Aluminum trilaurate, as the product " Micro-titanium Dioxide MT 100 S " of TAYCA company,
-ferrum oxide and ferric stearate, as the product " Micro-titanium Dioxide MT 100 F " of TAYCA company,
-silicon dioxide, aluminium oxide and siloxanes, as the product " Micro-titanium Dioxide MT 100 SAS " of TAYCA company, " Microtitanium Dioxide MT 600 SAS " and " Microtitanium Dioxide MT 500 SAS ",
-sodium hexameta phosphate, as the product " MicrotitaniumDioxide MT 100 W " of TAYCA company,
-octyl group trimethoxy siloxane, as the product " T-805 " of DEGUSSA company,
-aluminium oxide and stearic acid, as the product " UVT-M160 " of KEMIRA company,
-aluminium oxide and glycerol, as the product " UVT-M212 " of KEMIRA company,
-aluminium oxide and siloxanes are as the product " UVT-M262 " of KEMIRA company.
-titanium oxide also can use with the pigment paste form, promptly for example uses with the paste mixture form, and this mixture also contains one or more oil and a kind of dispersants except that TiO 2 pigment.Use pigment paste to allow to add a kind of not causing and use difficulty than relatively large pigment.
According to the present invention, the use amount of titanium oxide is 0.05-20% (weight) preferably, more preferably is 0.5-10% (weight).
Being coated with the compositions that contains coordination compound of the present invention can reach and make skin significantly pure white.
So, it is about the cosmetic of skin whitening and/or the method for dermatological that the present invention also has a content, this method is to be coated with a kind of compositions on skin, this compositions contains at least a 'alpha '-hydroxy acids and at least a titanium oxide cooperates as unique skin whitener.Use the 'alpha '-hydroxy acids and at least a titanium oxide of effective dose, so that can see intuitively that skin is brightened after the described compositions of coating.The present composition especially is fit to non-Caucasian, specifically is Black people's skin and Asian skin.
The compositions that contains coordination compound of the present invention can be any lid human relations form that just is being usually used in local coating, for example be solution, gel, washing liquid or emulsion type dispersion liquid, milk type liquid or half-the stiff emulsifying of liquid is aqueous, they are to contain aqueous phase (H/E) by fat is dispersed in mutually, (E/H) prepares perhaps conversely, perhaps be soft, semisolid or the solid stiff suspension or the emulsion of butter or gel type, or be the blister dispersion liquid of microemulsion, microgranule or ion and/or nonionic type.These compositionss prepare according to usual way.
Known, cosmetic of the present invention or dermatological compositions can contain make up or dermatological field in common additive, as emulsifying agent, hydrophilic or lipophilic gellant, hydrophilic or lipophilic activating agent, antiseptic, antioxidant, spice, filler, sunscreen and the coloured material different with titanium oxide and 'alpha '-hydroxy acids.The amount of these different additive is normally used amount, for example 0.01-20% of composition total weight in cosmetic or dermatological field.These additives can add according to their character fat mutually in, contain the water neutralization/or the class fat vacuole in.
As emulsifying agent,, can use water-in-oil emulsifier (E/H) or oil-in-water (H/E) emulsifying agent according to desired final emulsion liquid situation.
As emulsifying agent, for example can enumerate the stearate mixture (by the Arlacel 165 of ICI company sale) of tristerin/PEG-100, the stearate (by the Myrj49 of ICI company sale) of PEG-20, the stearate (by the Myrj52 of ICI company sale) of PEG-40, three stearic acid (by the Span65 of ICI company sale) of sorbitan.
The ratio of emulsifying agent can be to count 0.1-15% (weight) with the gross weight of compositions, preferably 0.5-5% (weight).
Can add coemulsifier in the present composition, for example in the gross weight of said composition, its amount is 0.05-10% (weight).As auxilliary emulsifying agent, can enumerate tristerin.
In class fat vacuole dispersion liquid, emulsifying agent can be made of bubble itself, ion lipoid and/or nonionic class fat vacuole.
As spendable oil among the present invention, can enumerate mineral oil, vegetable oil (maize embryo oil), artificial oil (2-Methylpentadecane), silicone oil (Cyclom é thicone) and contain fluorocarbon oil.Can also use aliphatic alcohol (stearyl alcohol, hexadecanol), fatty acid (stearic acid) and wax.
As the hydrophilic active agent, for example can use protein or protein hydrolysate, aminoacid, polyhydric alcohol, specifically be glycerol or Sorbitol, carbamide, allantoin, sucrose and their derivant, glycyrrhetinic acid.
As lipophilic active agents, can enumerate tocopherol (vitamin E) and their derivant, basic fatty oil, ceramide, base oil.
In these compositionss, can also use UV (ultraviolet) sunscreen, the oxide of zinc with oleophylic or hydrophilic nmature.
These compositionss have constituted the butter of treatment or nursing face, hands or health particularly, washing liquid, the gel of tangible precursor emulsion, skin nursing or the treatment of protection or nursing or rub this.
The invention has been described for the following examples.In these embodiments, pointed ratio is a percetage by weight. embodiment 1:H/E emulsion: the facial milk oil phase A1:Arlacel 165 1.2%Myrj 49 1.2% maize germ 5%Cyclom é thicone 10% stearic acid 0.6% stearyl alcohol 0.6% hexadecanol 0.6% anticorrisive agent 0.3% oil phase A2 that brightens: isohexadecane 5% titanium dioxide (the Tioxide A-HRC of selection) 5% water: glycolic 3% NaOH in right amount to pH 3.8% glycerine 3% water in right amount to 100%
Mode of operation: oil phase A1 is heated to 80 ℃.In addition, titanium oxide is dispersed in the 2-Methylpentadecane preparation oil phase A2.Then phase A1 and A2 are mixed, again mixture is under agitation poured into aqueous phase.Cool off when keeping stirring.
Obtain having the white milk of the character of brightening.Embodiment 2:H/E emulsion: the facial milk that brightens
Embodiment 2 is identical with embodiment 1; Just contain surface-treated titanium dioxide (Microtitanium Dioxide MT 100 T, Tayca company) as titanium dioxide embodiment 3:H/E emulsion: hand and health are used brightens milk oil phase A1: hexadecanol 0.6%Span65 1.9%Myrj52 0.85% glyceryl stearate 2%Cyclom é thicone 8% tocopherol acetate 0.5% oil phase A2: isohexadecane 5% titanium dioxide (the Tioxide A-HRC Tioxide company product of selection) 5% water: glycolic 2.9% citric acid 0.9% lactic acid 3.1% tartaric acid 0.1% NaOH in right amount to pH 3 glycerine 4% anticorrisive agent 0.3% water in right amount to 100%
Mode of operation is identical with embodiment's 1.
The milk that coating obtains can reach good whitening effect.
Claims (16)
1. when preparing cosmetic and/or dermatological compositions and/or be used for preparation cosmetic and/or dermatological compositions, at least a 'alpha '-hydroxy acids and at least a titanium oxide are cooperated as skin whitener.
2. application according to claim 1 is characterized in that 'alpha '-hydroxy acids is the Alpha-hydroxy alkanoic acid.
3. application according to claim 1 and 2 is characterized in that 'alpha '-hydroxy acids is selected from the group that comprises following chemical compound: glycolic, lactic acid, maleic acid, tartaric acid, citric acid, mandelic acid, Alpha-hydroxy are sad, Alpha-hydroxy caproic acid, Alpha-hydroxy capric acid, Alpha-hydroxy dodecylic acid, Alpha-hydroxy tetradecanoic acid, Alpha-hydroxy hexadecanoic acid, Alpha-hydroxy octadecanoid acid, Alpha-hydroxy arachic acid, Alpha-hydroxy behenic acid, Alpha-hydroxy hexacosoic acid, Alpha-hydroxy octocosoic acid.
4. the described application of arbitrary claim in requiring according to aforesaid right is characterized in that titanium oxide is a titanium dioxide.
5. require described application according to aforesaid right, it is characterized in that titanium dioxide is surface treated.
6. the described application of arbitrary claim in requiring according to aforesaid right, it is characterized in that: the concentration of 'alpha '-hydroxy acids is to count 0.01-50% (weight) with the gross weight of compositions.
7. require described application according to aforesaid right, it is characterized in that: the concentration of 'alpha '-hydroxy acids is to count 0.5-20% (weight) with the gross weight of compositions.
8. the described application of arbitrary claim in requiring according to aforesaid right, it is characterized in that: the concentration of titanium oxide is to count 0.05-20% (weight) with the gross weight of compositions.
9. require described application according to aforesaid right, it is characterized in that: the concentration of titanium oxide is to count 0.5-10% (weight) with the gross weight of compositions.
10. the described application of arbitrary claim in requiring according to aforesaid right is characterized in that the last pH of compositions is 2.5-6.
11. according to the described application of arbitrary claim in the aforesaid right requirement, it is characterized in that: compositions is water-in-oil emulsion, oil-in-water emulsion, microemulsion, serum, blister dispersion liquid.
12. the method for skin whitening, this method is: be coated with a kind of compositions on skin, this compositions contains at least a 'alpha '-hydroxy acids and at least a titanium oxide matches as unique skin whitener.
13. method according to claim 12 is characterized in that compositions is coated on non-Caucasian's the skin.
14. according to claim 12 or 13 described methods, it is characterized in that: 'alpha '-hydroxy acids is the Alpha-hydroxy alkanoic acid.
15. according to the described method of arbitrary claim among the claim 12-14, it is characterized in that: 'alpha '-hydroxy acids is selected from the group that comprises following chemical compound: glycolic, lactic acid, maleic acid, tartaric acid, citric acid, mandelic acid, Alpha-hydroxy are sad, Alpha-hydroxy caproic acid, Alpha-hydroxy capric acid, Alpha-hydroxy dodecylic acid, Alpha-hydroxy tetradecanoic acid, Alpha-hydroxy hexadecanoic acid, Alpha-hydroxy octadecanoid acid, Alpha-hydroxy arachic acid, Alpha-hydroxy behenic acid, Alpha-hydroxy hexacosoic acid, Alpha-hydroxy octocosoic acid.
16., it is characterized in that titanium oxide is a titanium dioxide according to the described method of arbitrary claim among the claim 12-15.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9507664A FR2735688B1 (en) | 1995-06-26 | 1995-06-26 | USE IN COMBINATION OF AN ALPHA-HYDROXYACID AND A TITANIUM OXIDE FOR SKIN WHITENING |
| FR9507664 | 1995-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1146893A true CN1146893A (en) | 1997-04-09 |
Family
ID=9480399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96111043A Pending CN1146893A (en) | 1995-06-26 | 1996-06-25 | Use in combination of alpha-hydroxy acid and titanium oxide for lightening skin |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPH0912442A (en) |
| KR (1) | KR970000218A (en) |
| CN (1) | CN1146893A (en) |
| FR (1) | FR2735688B1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10265362A (en) * | 1997-03-19 | 1998-10-06 | Yakult Honsha Co Ltd | Cosmetic |
| CA2283574A1 (en) * | 1998-01-16 | 1999-07-22 | Color Access, Inc. | Stabilized whitening compositions and method of preparing same |
| US5980904A (en) * | 1998-11-18 | 1999-11-09 | Amway Corporation | Skin whitening composition containing bearberry extract and a reducing agent |
| GB0006867D0 (en) * | 2000-03-21 | 2000-05-10 | Unilever Plc | Method and composition for skin lightening |
| WO2001070190A2 (en) * | 2000-03-23 | 2001-09-27 | Unilever Plc | Cosmetic compositions |
| GB0102235D0 (en) * | 2001-01-29 | 2001-03-14 | Unilever Plc | Method and product for skin lightening |
| US7429391B2 (en) | 2004-01-30 | 2008-09-30 | Access Business Group International Llc | Holistic composition and method for reducing skin pigmentation |
| US20090317341A1 (en) * | 2008-06-18 | 2009-12-24 | Conopco, Inc., D/B/A Unilever | Compositions for Lightening Skin Color |
| DE102010051689A1 (en) * | 2010-11-17 | 2012-05-24 | Merck Patent Gmbh | Dihydroxyfumaric acid derivatives and their use for skin lightening |
| FR3002844B1 (en) | 2013-03-05 | 2016-08-12 | Sensient Cosmetic Tech | PULVERULENT COMPOSITION USEFUL FOR THE PREPARATION OF LAUNDRY COSMETIC COMPOSITIONS |
| KR101629368B1 (en) | 2014-08-13 | 2016-06-10 | (주)클레어스코리아 | Cosmetic composition for whitening skin and the manufacturing method therof |
| KR102248022B1 (en) * | 2020-07-13 | 2021-05-04 | (주)포인트엔지니어링 | Substrate for optical device package and optical device package comprising the same |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5091171B2 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
| JP2751965B2 (en) * | 1988-04-30 | 1998-05-18 | 川研ファインケミカル株式会社 | Cosmetics |
| JPH0699368B2 (en) * | 1988-08-26 | 1994-12-07 | ユニリーバー・ナームローゼ・ベンノートシヤープ | Cosmetic composition |
| JP2593714B2 (en) * | 1989-09-20 | 1997-03-26 | 株式会社 林原生物化学研究所 | Whitening agent |
| GB9109965D0 (en) * | 1991-05-07 | 1991-07-03 | Unilever Plc | Cosmetic composition |
| DE59209789D1 (en) * | 1991-06-14 | 2000-02-10 | Merck Patent Gmbh | Preparation of a neutral titanium oxide sol |
| IL99291A (en) * | 1991-08-23 | 1997-04-15 | Fischer Pharma Ltd | Cosmetic preparations |
| GB9218779D0 (en) * | 1992-09-04 | 1992-10-21 | Unilever Plc | Antiperspirant actives and compositions |
| JP3230327B2 (en) * | 1993-03-22 | 2001-11-19 | 株式会社ツムラ | Surface foaming bath agent |
| JP2831552B2 (en) * | 1993-12-24 | 1998-12-02 | ザ、プロクター、エンド、ギャンブル、カンパニー | Oily solid cosmetics containing acid dyes |
| US5393526A (en) * | 1994-02-07 | 1995-02-28 | Elizabeth Arden Company, Division Of Conopco, Inc. | Cosmetic compositions |
| JPH0827490A (en) * | 1994-07-18 | 1996-01-30 | Shiseido Co Ltd | Solid soap |
| JPH0853321A (en) * | 1994-08-10 | 1996-02-27 | Kao Corp | Oily solid cosmetic |
| DE4444237C2 (en) * | 1994-12-13 | 2000-08-24 | Beiersdorf Ag | Use of combinations of active ingredients to combat blemished skin caused by Propionibacterium acnes and mild forms of acne |
| FR2728167A1 (en) * | 1994-12-15 | 1996-06-21 | Cird Galderma | COSMETIC OR DERMATOLOGICAL COMPOSITION IN THE FORM OF WATER EMULSION IN OIL WITH HIGH HYDROXYACID CONTENT |
| JPH08283119A (en) * | 1995-04-07 | 1996-10-29 | Kao Corp | Skin lightener |
| JP3540432B2 (en) * | 1995-04-19 | 2004-07-07 | ライオン株式会社 | Detergent composition containing amidocarboxylic acid or salt thereof |
-
1995
- 1995-06-26 FR FR9507664A patent/FR2735688B1/en not_active Expired - Fee Related
-
1996
- 1996-06-14 KR KR1019960021595A patent/KR970000218A/en not_active Application Discontinuation
- 1996-06-25 CN CN96111043A patent/CN1146893A/en active Pending
- 1996-06-25 JP JP8164886A patent/JPH0912442A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2735688B1 (en) | 1997-08-14 |
| KR970000218A (en) | 1997-01-21 |
| JPH0912442A (en) | 1997-01-14 |
| FR2735688A1 (en) | 1996-12-27 |
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