CN114681579A - Traditional Chinese medicine granules for treating calf new roundworm intestinal obstruction and preparation method thereof - Google Patents
Traditional Chinese medicine granules for treating calf new roundworm intestinal obstruction and preparation method thereof Download PDFInfo
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- 239000008187 granular material Substances 0.000 title claims abstract description 20
- 208000003243 intestinal obstruction Diseases 0.000 title claims abstract description 13
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- 241000244203 Caenorhabditis elegans Species 0.000 title claims description 9
- 238000002360 preparation method Methods 0.000 title description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
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- 239000000047 product Substances 0.000 claims abstract description 11
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 5
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
A Chinese medicinal granule for treating neonatal ascaris intestinal obstruction in calves comprises radix aucklandiae, Arecae semen, rhizoma Cyperi, Curcumae rhizoma, radix Codonopsis, and Coptidis rhizoma. In the invention, the components are weighed according to the measurement, water is added for decoction twice, the filtrate is combined and concentrated, the mixture is dried and crushed, cane sugar is added, and the finished product is prepared after granulation, sieving, drying and sieving again. When in use, the feed is mixed with water according to a certain proportion, and then the feed is fed to the sick cattle with empty stomach, and after the feed is continuously used for 3 days, the clinical symptoms are obviously improved.
Description
Technical Field
The invention belongs to the field of veterinary medicines, and particularly relates to traditional Chinese medicine granules for treating calf new roundworm intestinal obstruction and a preparation method thereof.
Background
The calf ascaris Neoascaris ileus refers to intestinal infarction caused by entanglement of large amount of calf ascaris Neoascaris (Neoascaris vitulorum) parasitizing in calf intestine. The symptoms of the calf are abdominal pain, abdominal distension, diarrhea or constipation, when the calf is heavy, the abdomen has a water beating sound, and the feces have worm eggs or worm bodies. The diarrhea of the calf at the beginning of the calf, the milk is discharged in white or grey white cement sample, and the taste is fishy. The treatment with antibacterial agent and digestive agent is ineffective. The large insects mixed with milky white, cylindrical and tippy ends can be found by examining the feces in a few cases. And after 2-4 days, the appetite is lost. Abdominal distension and dull sensation. Nasal sweat is sometimes absent, and people do not want to walk and like to lie down. When abdominal pain is severe, sweating, lying on the side, groaning, opening the mouth, whetting a breath, and whitening the eyes. Dry and hard stools or constipation. A deep-red mouth with a white and greasy coating. Auscultation, accelerated heartbeat and enhanced heart sound. The stomach sounds were low or even stopped, and palpation was soft and elastic with noticeable "swooshing" like sloshing sounds. In severe cases, there is a sloshing sound in the right flank. The body temperature is 39-39.6 ℃.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides the traditional Chinese medicine granules for treating the calf new roundworm ileus, which are scientific in proportioning, good in treatment effect and free of toxic and side effects.
The technical scheme adopted by the invention is as follows:
a traditional Chinese medicine granule for treating calf new roundworm ileus is characterized in that: the composition comprises the following components in parts by weight:
10-13 parts of costustoot;
5-10 parts of betel nuts;
3-5 parts of rhizoma cyperi;
3-5 parts of curcuma zedoary;
3-5 parts of sophora flavescens;
3-5 parts of coptis chinensis.
And the composition comprises the following components mixed according to the parts by weight:
12 parts of costustoot;
7 parts of betel nuts;
3 parts of rhizoma cyperi;
4 parts of curcuma zedoary;
4 parts of sophora flavescens;
and 3 parts of coptis chinensis.
The invention also aims to provide a preparation method of the traditional Chinese medicine granules for treating calf neoascaris intestinal obstruction, which is characterized by comprising the following steps of: the method comprises the following steps:
weighing costustoot, areca nut, rhizoma cyperi, curcuma zedoary, codonopsis pilosula and coptis chinensis according to measurement, and adding 10 times of weight of clear water for decocting;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates, standing for 24 hours, and concentrating the supernatant to 80 ℃ until the relative density is 1.28;
fourthly, drying the product obtained in the step three at 60-70 ℃, then crushing, adding cane sugar, and uniformly stirring;
and fifthly, adding the product obtained in the step four and 85% ethanol into a granulator for granulation, sieving the granules with a 10-mesh sieve, then drying at 60 ℃, and sieving with the 10-mesh sieve to obtain the finished product.
The invention also aims to provide a use method of the traditional Chinese medicine granules for treating calf neoascaris intestinal obstruction, which is characterized by comprising the following steps: the medicament of claim is mixed with water at a weight ratio of 1:500, fed on an empty stomach, and administered continuously for 3 days.
The invention has the advantages and positive effects that:
according to the invention, costustoot, areca nut, rhizoma cyperi, curcuma zedoary, codonopsis pilosula and coptis are weighed according to the measurement, water is added for decoction twice, the filtrate is combined and concentrated, the mixture is dried and crushed, cane sugar is added, and the mixture is granulated, sieved, dried and sieved again to obtain the finished product. When in use, the feed is mixed with water according to a certain proportion and then fed to sick cattle, and after continuous administration for 3 days, the clinical symptoms are obviously improved.
Detailed Description
The present invention is further illustrated by the following examples, which are intended to be illustrative, not limiting and are not intended to limit the scope of the invention.
The invention discloses a traditional Chinese medicine granule for treating calf new roundworm intestinal obstruction, which is characterized in that: the composition comprises the following components in parts by weight:
10-13 parts of costustoot;
5-10 parts of betel nuts;
3-5 parts of rhizoma cyperi;
3-5 parts of curcuma zedoary;
3-5 parts of sophora flavescens;
3-5 parts of coptis chinensis.
More preferred embodiments are: the composition comprises the following components in parts by weight:
12 parts of costustoot;
7 parts of areca;
3 parts of rhizoma cyperi;
4 parts of curcuma zedoary;
4 parts of sophora flavescens;
and 3 parts of coptis chinensis.
The sick cattle are blocked by the intestinal excrement due to internal disturbance of the parasitic infestation, pain is caused by obstruction and obstruction of the intestine, the qi stagnation causes the swelling, and the food is stopped to generate hydrops. However, the young calves have incomplete blood and qi, are delicate and weak in young bodies, have long-term diseases, consume blood and damage essence, and are weak in spleen and stomach, and the clinical symptoms are the symptoms of deficiency in origin and excess pathogenic factors. So it is pungent, sweet, warm and moist, blood-nourishing, intestine-moistening and stir-baked with oil to enhance its moistening effect. Strengthen the body resistance and attack the body resistance, so that the pathogenic factors can descend without damaging the body resistance. Aucklandia lappa and Areca catechu can promote qi stagnation and expel and kill intestinal parasites; rhizoma Cyperi and Curcumae rhizoma for regulating qi and removing food retention; ku Shen and Huang Lian are bitter in flavor and can dry dampness and nourish parasites. The compatibility of the herbs can warm and moisten the middle, promote qi circulation, remove stagnation, attack accumulation and kill parasites.
Example 1
A Chinese medicinal granule for treating calf neoascaris intestinal obstruction and its preparation method are provided, which comprises the following components:
12 parts of costustoot, 7 parts of areca nut, 3 parts of rhizoma cyperi, 4 parts of curcuma zedoary, 4 parts of codonopsis pilosula and 3 parts of coptis chinensis
Weighing costustoot, areca nut, rhizoma cyperi, curcuma zedoary, codonopsis pilosula and coptis chinensis according to measurement, and adding 10 times of weight of clear water for decocting;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates, standing for 24 hours, and concentrating the supernatant to 80 ℃ until the relative density is 1.28;
fourthly, drying the product obtained in the third step at 60-70 ℃, then crushing, adding cane sugar, and uniformly stirring;
and fifthly, adding the product obtained in the step four and 85% ethanol into a granulator for granulation, sieving the granules with a 10-mesh sieve, then drying at 60 ℃, and sieving with the 10-mesh sieve to obtain the finished product.
Example 2
A Chinese medicinal granule for treating calf neoascaris intestinal obstruction comprises the following components:
10 parts of costustoot, 9 parts of areca nut, 4 parts of rhizoma cyperi, 4 parts of curcuma zedoary, 3 parts of codonopsis pilosula and 3 parts of coptis chinensis
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
Example 3
A Chinese medicinal granule for treating calf neoascaris intestinal obstruction comprises the following components:
11 parts of costustoot, 5 parts of areca nut, 3 parts of nutgrass galingale rhizome, 3 parts of zedoary, 4 parts of codonopsis pilosula and 4 parts of coptis chinensis
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
Example 4
A Chinese medicinal granule for treating calf neoascaris intestinal obstruction comprises the following components:
12 parts of costustoot, 5 parts of areca nut, 3 parts of nutgrass galingale rhizome, 3 parts of zedoary, 4 parts of codonopsis pilosula and 4 parts of coptis chinensis
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
And (3) clinical tests:
the administration mode comprises the following steps: administration by drinking water
Administration dose: 2g, adding 1kg of water, and administering on an empty stomach.
In 5 months in 2019, 12 calves diagnosed with the new ascaris intestinal obstruction in the calves are treated with the medicament in the example 1, and after continuous administration for 3 days, the clinical symptoms of the sick calves are obviously improved.
Claims (4)
1. A traditional Chinese medicine granule for treating calf new roundworm ileus is characterized in that: the composition comprises the following components in parts by weight:
10-13 parts of costustoot;
5-10 parts of betel nuts;
3-5 parts of rhizoma cyperi;
3-5 parts of curcuma zedoary;
3-5 parts of sophora flavescens;
3-5 parts of coptis chinensis.
2. The traditional Chinese medicine granule for treating calf new roundworm ileus according to claim 1, which is characterized in that: the composition comprises the following components in parts by weight:
12 parts of costustoot;
7 parts of areca;
3 parts of rhizoma cyperi;
4 parts of curcuma zedoary;
4 parts of sophora flavescens;
and 3 parts of coptis chinensis.
3. The traditional Chinese medicine granule for treating calf neoascaris intestinal obstruction according to claim 1 or 2, characterized in that: the method comprises the following steps:
weighing costustoot, areca nut, rhizoma cyperi, curcuma zedoary, codonopsis pilosula and coptis chinensis according to measurement, and adding 10 times of weight of clear water for decocting;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates, standing for 24 hours, and concentrating the supernatant to 80 ℃ until the relative density is 1.28;
fourthly, drying the product obtained in the step three at 60-70 ℃, then crushing, adding cane sugar, and uniformly stirring;
and fifthly, adding the product obtained in the step four and 85% ethanol into a granulator for granulation, sieving the granules with a 10-mesh sieve, then drying at 60 ℃, and sieving with the 10-mesh sieve to obtain the finished product.
4. A traditional Chinese medicine granule for treating calf new roundworm ileus is characterized in that: the medicament of claim 1 or 2 is mixed with water in a weight ratio of 1:500 and fed on an empty stomach for 3 consecutive days.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011611433.2A CN114681579A (en) | 2020-12-31 | 2020-12-31 | Traditional Chinese medicine granules for treating calf new roundworm intestinal obstruction and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011611433.2A CN114681579A (en) | 2020-12-31 | 2020-12-31 | Traditional Chinese medicine granules for treating calf new roundworm intestinal obstruction and preparation method thereof |
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