CN114669258A - A thick material reaction series production line for bio-pharmaceuticals - Google Patents
A thick material reaction series production line for bio-pharmaceuticals Download PDFInfo
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- CN114669258A CN114669258A CN202210308628.2A CN202210308628A CN114669258A CN 114669258 A CN114669258 A CN 114669258A CN 202210308628 A CN202210308628 A CN 202210308628A CN 114669258 A CN114669258 A CN 114669258A
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- 238000006243 chemical reaction Methods 0.000 title claims abstract description 73
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 17
- 229960000074 biopharmaceutical Drugs 0.000 title claims abstract description 16
- 239000000463 material Substances 0.000 title claims description 8
- 238000002425 crystallisation Methods 0.000 claims abstract description 57
- 230000008025 crystallization Effects 0.000 claims abstract description 57
- 239000000376 reactant Substances 0.000 claims abstract description 26
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000011345 viscous material Substances 0.000 claims abstract description 17
- 238000001514 detection method Methods 0.000 claims abstract description 14
- 230000006698 induction Effects 0.000 claims abstract description 11
- 238000007789 sealing Methods 0.000 claims abstract description 8
- 238000005096 rolling process Methods 0.000 claims abstract description 6
- 230000005540 biological transmission Effects 0.000 claims description 7
- 241000883990 Flabellum Species 0.000 claims description 3
- 230000006978 adaptation Effects 0.000 claims description 3
- 239000012780 transparent material Substances 0.000 claims description 3
- 239000000126 substance Substances 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 6
- 239000007787 solid Substances 0.000 abstract description 6
- 239000013078 crystal Substances 0.000 description 13
- 238000003756 stirring Methods 0.000 description 3
- 238000001816 cooling Methods 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000013547 stew Nutrition 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0063—Control or regulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0053—Details of the reactor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0053—Details of the reactor
- B01J19/0066—Stirrers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/001—Feed or outlet devices as such, e.g. feeding tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/08—Cleaning containers, e.g. tanks
- B08B9/087—Cleaning containers, e.g. tanks by methods involving the use of tools, e.g. brushes, scrapers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B9/00—Presses specially adapted for particular purposes
- B30B9/02—Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material
- B30B9/12—Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material using pressing worms or screws co-operating with a permeable casing
- B30B9/128—Vertical or inclined screw presses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B9/00—Presses specially adapted for particular purposes
- B30B9/02—Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material
- B30B9/12—Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material using pressing worms or screws co-operating with a permeable casing
- B30B9/14—Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material using pressing worms or screws co-operating with a permeable casing operating with only one screw or worm
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D2009/0086—Processes or apparatus therefor
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
The invention discloses a reaction series production line for viscous materials for bio-pharmaceuticals, which comprises a reaction kettle main body, a feeding port, a reactant inlet, a sealing valve, a one-way valve, a conveyor belt, a flood dragon plate, a sleeve, a standing reactor, a drainage channel plate, an accelerator, an inductor, an induction door and a rolling rod, wherein the feeding port and the reactant inlet are arranged on the reaction kettle main body, the sealing valve is also arranged on the reaction kettle main body, the one-way valve is arranged on the reaction kettle main body, and a detection push rod is correspondingly arranged at the port position of the one-way valve. The standing reactor arranged in the reaction kettle main body can fully react the sticky substances with the reactants, then the sticky substances and the reactants are separated into a solid state form and a liquid state form, and the liquid with higher purity is crystallized to obtain high-purity crystallized substances, so that the reactions are all in a safe and sealed environment, and the purity of the crystallized substances in the continuous crystallization process can be continuously detected.
Description
Technical Field
The invention relates to the technical field of viscous material reaction, in particular to a viscous material reaction series production line for bio-pharmaceuticals.
Background
The reaction and preparation of various sticky materials in the field of biological pharmacy are required to use the reaction kettle, and the reaction kettle is largely applied because of the vacuum and sterile environment in the kettle, but under the condition of ensuring sterile precursors, the reaction condition in the kettle can not be effectively observed, and finally obtained experimental data is influenced, so that in the process of reusing the reaction kettle, if the unfavorable observation on the reaction condition in the kettle can be overcome, the whole reaction series production line can be better improved.
The existing viscous material reaction production line only has the application of stirring, heating and cooling of a reaction kettle, the production line of the reaction is still imperfect, and intelligent and real-time purity detection of crystals cannot be achieved, for example, the viscous material cooling reaction kettle disclosed by application number 20110628810.1 cannot provide real-time parameter comparison of purity in the whole reaction production line, cannot convey extracts with qualified purity, and cannot intelligently and improve the working efficiency.
Therefore, it is necessary to invent a viscous material reaction series production line for biopharmaceuticals to solve the above problems.
Disclosure of Invention
The invention aims to provide a viscous material reaction series production line for bio-pharmaceuticals, and aims to solve the problems that the production line for viscous material reaction in the technology cannot detect the purity of crystals in real time, and the whole production line and reaction process cannot be intelligent and efficient.
In order to achieve the above purpose, the invention provides the following technical scheme: a viscous material reaction series production line for bio-pharmaceuticals comprises a reaction kettle main body, a feeding port, a reactant inlet, a sealing valve, a one-way valve, a conveyor belt, a flood dragon plate, a sleeve, a standing reactor, a drainage trough plate, an accelerator, an inductor, an induction door and a rolling rod, wherein the feeding port and the reactant inlet are formed in the reaction kettle main body, the sealing valve is further arranged on the reaction kettle main body, the one-way valve is arranged on the reaction kettle main body, a detection push rod is correspondingly arranged at the port position of the one-way valve, a display and a sensor are connected on the detection push rod, a crystallization outlet and a turbid liquid outlet are formed in the reaction kettle main body, the conveyor belt is correspondingly arranged at the outlet position of the crystallization, a flood dragon plate is arranged at the bottom in the reaction kettle main body, a drainage rod and a chain wheel are fixedly connected at the bottom of the flood dragon plate, the chain wheel is connected with a second chain wheel through a chain, no. two sprocket fixed settings are connected with the cylindrical cam, sliding connection has the sleeve on the cylindrical cam, install U type scraper blade on the sleeve, U type scraper blade and crystallization board sliding connection, crystallization board fixed connection is on the reactor of stewing, install on the drainage cell board flood dragon board bottom, install the accelerator on the flood dragon board, be provided with inductor and induction door in the crystallization export, evenly be provided with the roll bar in the crystallization export.
Preferably, the pan feeding mouth and the equal fixed connection of reactant entry are in the reation kettle main part, just pan feeding mouth and reactant entry's orientation is opposite, and all be provided with manual stop valve on pan feeding mouth and the reactant entry for the material volume in the reation kettle main part is by manual control.
Preferably, the power electric connection of detection push rod and sensor and display, just the detection push rod is automatic telescopic link, and the detection push rod tip is provided with the detector, realizes that reaction crystallization process and purity in the reation kettle main part are detected by real-time.
Preferably, the crystallization outlet is a funnel-shaped transparent material, the crystallization outlet is in sliding connection with the rectangular induction door, and the amount of the crystals can be directly observed through the crystallization outlet.
Preferably, the flood dragon plate has a diameter which changes from large to small from top to bottom, the maximum diameter of the flood dragon plate is twice of the minimum diameter, and under the action of the flood dragon plate, the solid after the solid-liquid separation of the reactants can be stirred for the second time.
Preferably, drainage stick fixed connection is on flood dragon board's transmission shaft, flood dragon board's transmission shaft passes through the bearing and installs on the drainage groove board, the length of cylindrical cam and the length looks adaptation of crystallization board, just there is the slide bar between cylindrical cam and the hollow sleeve.
Preferably, circular through holes are uniformly formed in the crystallization plate, and the surface of the crystallization plate is in contact with the U-shaped scraper.
Preferably, the reactor of stewing is last evenly to have seted up the rectangular hole, just the reactor of stewing is the figure that pitch arc and straight line are constituteed, be provided with the bar groove on the drainage channel board, and the size and the flood dragon board flabellum thickness of its bar groove are corresponding suitable.
In the technical scheme, the invention provides the following technical effects and advantages:
1. the sticky matter and the reactant can be fully reacted through a standing reactor arranged in the reaction kettle main body, then the reaction product is separated into a solid state form and a liquid state form, and then the liquid with higher purity is crystallized to obtain a high-purity crystal substance, so that the reactions in the series are all in a safe and sealed environment, and the purity of the crystal substance in the continuous crystallization process can be continuously detected;
2. the reacted solid and liquid can be respectively conveyed through the flood dragon plate and the drainage rod, under the acceleration effect, the stirring speed of the flood dragon plate is accelerated, the efficiency is higher, the centrifugal force applied to the drainage rod is larger, the liquid thrown out of the crystallization plate is quicker and more efficient, and the efficiency of obtaining crystals is higher;
3. through the high temperature crystallization on the crystallization board, will throw out the liquid quick crystallization on the crystallization board, the crystallization after the crystallization thing is constantly scraped by U type scraper blade, is carried the crystallization export, on being carried conveyer belt and ripe production line, whole reaction and the process of crystallization are intelligent and aseptic.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic perspective view of the rolling bar of the present invention;
FIG. 3 is a schematic view of the internal structure of the reaction vessel main body according to the present invention;
FIG. 4 is a perspective cross-sectional view of a reactor body according to the present invention;
FIG. 5 is a schematic view of a crystallization plate according to the present invention;
FIG. 6 is a schematic perspective view of the drainage rod of the present invention;
FIG. 7 is a reaction scheme of the present invention.
Description of reference numerals:
1. a reaction kettle main body; 2. a feeding port; 3. a reactant inlet; 4. a sealing valve; 5. a one-way valve; 6. detecting the push rod; 7. a display; 8. a sensor; 9. a crystallization outlet; 10. a turbid liquid outlet; 11. a conveyor belt; 12. a flood dragon plate; 13. a drainage rod; 14. a first chain wheel; 15. a chain; 16. a second sprocket; 17. a cylindrical cam; 18. a sleeve; 19. a U-shaped scraper; 20. crystallizing the plate; 21. standing the reactor; 22. a drainage channel plate; 23. an accelerator; 24. an inductor; 25. an induction door; 26. a roll bar.
Detailed Description
In order to make the technical solutions of the present invention better understood, those skilled in the art will now describe the present invention in further detail with reference to the accompanying drawings.
The invention provides a reaction series production line of viscous materials for bio-pharmaceuticals, which is shown in figures 1-7 and comprises a reaction kettle main body 1, a feeding port 2, a reactant inlet 3, a sealing valve 4, a one-way valve 5, a conveyor belt 11, a flood dragon plate 12, a sleeve 18, a standing reactor 21, a drainage trough plate 22, an accelerator 23, an inductor 24, an induction door 25 and a rolling rod 26, wherein the reaction kettle main body 1 is provided with the feeding port 2 and the reactant inlet 3, the reaction kettle main body 1 is also provided with the sealing valve 4, the reaction kettle main body 1 is provided with the one-way valve 5, the port position of the one-way valve 5 is correspondingly provided with a detection push rod 6, the detection push rod 6 is connected with a display 7 and a sensor 8, the reaction kettle main body 1 is provided with a crystallization outlet 9 and a turbid liquid outlet 10, the crystallization outlet 9 is correspondingly provided with the conveyor belt 11, the bottom of the reaction kettle main body 1 is provided with the flood dragon plate 12, flood dragon board 12 bottom fixedly connected with drainage stick 13 and sprocket 14, sprocket 14 is connected with sprocket 16 No. two through chain 15, fixed setting is connected with cylindrical cam 17 on sprocket 16 No. two, sliding connection has sleeve 18 on the cylindrical cam 17, install U type scraper blade 19 on the sleeve 18, U type scraper blade 19 and crystallization board 20 sliding connection, crystallization board 20 fixed connection is on reactor 21 that stews, install on drainage frid 22 flood dragon board 12 bottom, install accelerator 23 on the flood dragon board 12, be provided with inductor 24 and induction door 25 on the crystallization export 9, evenly be provided with roll bar 26 in the crystallization export 9.
Pan feeding mouth 2 and the equal fixed connection of reactant entry 3 are on reation kettle main part 1, and the orientation of pan feeding mouth 2 and reactant entry 3 is opposite to all be provided with manual stop valve on pan feeding mouth 2 and the reactant entry 3, detect the power electric connection of push rod 6 and sensor 8 and display 7, and detect that push rod 6 is automatic telescopic link, and detect that the 6 tip of push rod is provided with the detector.
Evenly be provided with circular through-hole on the crystallization board 20, and crystallization board 20 surface and the contact of U type scraper blade 19, evenly seted up the rectangular shape hole on the reactor 21 of stewing, and the reactor 21 of stewing is the figure that pitch arc and straight line are constituteed, is provided with the bar groove on the drainage frid 22, and the size in its bar groove suits with flood dragon board 12 flabellum thickness is corresponding.
The working principle of the invention is as follows:
referring to the attached drawings 1-3 of the specification, when the device is used, firstly, raw material sticky substances and reactants are conveyed into a reaction kettle main body 1 through a material inlet 2 and a reactant inlet 3, and stop valves on the material inlet 2 and the reactant inlet 3 can be opened and closed manually to open and close the conveying of the materials;
conveying the sticky matter and the reactant to a standing reactor 21 in a reaction kettle main body 1, separating solid from liquid after standing and reacting on the standing reactor 21, fixing and repeatedly stirring by a flood dragon plate 12, screening out effective components in the solid, flowing out along a notch of a drainage channel plate 22, and flowing out the residual turbid liquid along a turbid liquid outlet 10;
the reacted liquid is subjected to a great centrifugal force under the action of the drainage rod 13 and the accelerator 23, the liquid is continuously thrown out onto the crystallization plate 20, and the crystallization plate 20 rapidly heats and crystallizes the liquid to obtain a crystal with higher purity;
referring to the attached drawings 3-6 of the specification, when the device is used, crystals obtained through the crystallization plate 20 are driven by a first chain wheel 14, a chain 15 and a second chain wheel 16 which are connected to a transmission shaft of a flood dragon plate 12 rotating at a high speed, so that a cylindrical cam 17 rotates at a high speed, a sleeve 18 is driven to slide up and down along the direction of a surface groove of the cylindrical cam 17, and the crystals on the surface of the crystallization plate 20 are scraped and accumulated at a crystallization outlet 9;
after the crystallization outlet 9 is full, the sensor 24 obtains a signal, the sensor door 25 is opened, and the crystallized objects roll down onto the conveyor belt 11 along the rolling rod 26 and are conveyed to a mature production line;
certainly, in the process of continuously being reacted and crystallized in the reaction kettle main body 1, the sensor 8 can send a signal to the detection push rod 6, the detection push rod 6 is pushed towards the reaction kettle main body 1, the one-way valve 5 is opened and extends onto the crystallization plate 20, crystals on the crystallization plate 20 are detected, detected data are displayed by the display 7 in real time, and when the detection push rod 6 can detect crystals with proper purity, the crystals accumulated at the crystallization outlet 9 are judged to be qualified crystals.
Claims (8)
1. The utility model provides a thick material reaction series production line for bio-pharmaceuticals, includes reation kettle main part (1), pan feeding mouth (2), reactant entry (3), seal valve (4), check valve (5), conveyer belt (11), flood dragon board (12), sleeve (18), reactor (21), drainage frid (22), accelerator (23), inductor (24), induction door (25) and rolling rod (26) of stewing, its characterized in that: the reaction kettle comprises a reaction kettle body (1), a feeding port (2) and a reactant inlet (3) are arranged on the reaction kettle body (1), a sealing valve (4) is further arranged on the reaction kettle body (1), a check valve (5) is arranged on the reaction kettle body (1), a detection push rod (6) is correspondingly arranged at the port position of the check valve (5), a display (7) and a sensor (8) are connected onto the detection push rod (6), a crystallization outlet (9) and a turbid liquid outlet (10) are arranged on the reaction kettle body (1), a conveyor belt (11) is correspondingly arranged at the position of the crystallization outlet (9), a flood dragon plate (12) is arranged at the bottom of the reaction kettle body (1), a drainage rod (13) and a chain wheel (14) are fixedly connected at the bottom of the flood dragon plate (12), and the chain wheel (14) is connected with a second chain wheel (16) through a chain (15), no. two sprocket (16) are gone up fixed setting and are connected with cylindrical cam (17), sliding connection has sleeve (18) on cylindrical cam (17), install U type scraper blade (19) on sleeve (18), U type scraper blade (19) and crystallization board (20) sliding connection, crystallization board (20) fixed connection is on reactor (21) of stewing, install on drainage cell board (22) flood dragon board (12) bottom, install accelerator (23) on flood dragon board (12), be provided with inductor (24) and induction door (25) on crystallization export (9), evenly be provided with roll bar (26) in crystallization export (9).
2. The biopharmaceutical viscous material reaction train of claim 1, wherein said reaction train comprises: pan feeding mouth (2) and equal fixed connection of reactant entry (3) are on reation kettle main part (1), just pan feeding mouth (2) and the opposite orientation of reactant entry (3), and all be provided with manual stop valve on pan feeding mouth (2) and the reactant entry (3).
3. The biopharmaceutical viscous material reaction train of claim 1, wherein said reaction train comprises: detect push rod (6) and sensor (8) and display (7) power electric connection, just detect push rod (6) and be automatic telescopic link, and detect push rod (6) tip and be provided with the detector.
4. The biopharmaceutical viscous material reaction train of claim 1, wherein the at least one processing unit comprises: crystallization export (9) are the infundibulate of transparent material, crystallization export (9) and induction door (25) sliding connection of rectangle.
5. The biopharmaceutical viscous material reaction train of claim 1, wherein said reaction train comprises: the flood dragon board (12) is in the diameter from big to little change from top to little, and flood dragon board (12) maximum diameter is twice of minimum diameter.
6. The biopharmaceutical viscous material reaction train of claim 5, wherein said reaction train comprises: drainage stick (13) fixed connection is on flood dragon board's (12) transmission shaft, flood dragon board's (12) transmission shaft passes through the bearing and installs on drainage groove board (22), the length of cylindrical cam (17) and the length looks adaptation of crystallization board (20), just there is the slide bar between cylindrical cam (17) and hollow sleeve (18).
7. The biopharmaceutical viscous material reaction train of claim 6, wherein said reaction train comprises: circular through holes are uniformly formed in the crystallization plate (20), and the surface of the crystallization plate (20) is in contact with the U-shaped scraper (19).
8. The biopharmaceutical viscous material reaction train of claim 6, wherein said reaction train comprises: the reactor (21) of stewing is gone up and has evenly been seted up the rectangular hole, just reactor (21) of stewing is the figure that pitch arc and straight line are constituteed, be provided with the bar groove on drainage frid (22), and the size in its bar groove is suitable with flood dragon board (12) flabellum thickness is corresponding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210308628.2A CN114669258B (en) | 2022-03-25 | 2022-03-25 | A thick material reaction series production line for bio-pharmaceuticals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210308628.2A CN114669258B (en) | 2022-03-25 | 2022-03-25 | A thick material reaction series production line for bio-pharmaceuticals |
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| Publication Number | Publication Date |
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| CN114669258A true CN114669258A (en) | 2022-06-28 |
| CN114669258B CN114669258B (en) | 2024-05-14 |
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| CN202210308628.2A Active CN114669258B (en) | 2022-03-25 | 2022-03-25 | A thick material reaction series production line for bio-pharmaceuticals |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009151159A1 (en) * | 2008-06-10 | 2009-12-17 | Kndt&I Co., Ltd | Crystallization reaction apparatus for preparation of massive crystalline particles and crystalline separation processing system |
| CN205472715U (en) * | 2016-03-31 | 2016-08-17 | 青岛阿库卡稀有金属有限公司 | Rehenic acid ammonium crystallization purification device |
| KR20170093015A (en) * | 2016-02-04 | 2017-08-14 | 웰이앤씨 주식회사 | A reactor for crystallization |
| CN206701252U (en) * | 2017-03-22 | 2017-12-05 | 深圳市九明药业有限公司 | A kind of reactor of fully recovery crystallization |
| CN208426688U (en) * | 2018-06-20 | 2019-01-25 | 开封明仁药业有限公司 | Crystallizing tank is used in a kind of detection |
| CN209865362U (en) * | 2019-03-01 | 2019-12-31 | 盘锦百事达新材料有限公司 | Crystallization equipment for solid-liquid separation |
| CN211612710U (en) * | 2019-12-31 | 2020-10-02 | 湖北凌安科技有限公司 | Automatic centrifugal powder making device for raw materials of water reducing agent |
| CN113289372A (en) * | 2021-06-23 | 2021-08-24 | 江苏派克斯特纤维素有限公司 | Evaporative crystallization device for processing non-edible salt |
-
2022
- 2022-03-25 CN CN202210308628.2A patent/CN114669258B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009151159A1 (en) * | 2008-06-10 | 2009-12-17 | Kndt&I Co., Ltd | Crystallization reaction apparatus for preparation of massive crystalline particles and crystalline separation processing system |
| KR20170093015A (en) * | 2016-02-04 | 2017-08-14 | 웰이앤씨 주식회사 | A reactor for crystallization |
| CN205472715U (en) * | 2016-03-31 | 2016-08-17 | 青岛阿库卡稀有金属有限公司 | Rehenic acid ammonium crystallization purification device |
| CN206701252U (en) * | 2017-03-22 | 2017-12-05 | 深圳市九明药业有限公司 | A kind of reactor of fully recovery crystallization |
| CN208426688U (en) * | 2018-06-20 | 2019-01-25 | 开封明仁药业有限公司 | Crystallizing tank is used in a kind of detection |
| CN209865362U (en) * | 2019-03-01 | 2019-12-31 | 盘锦百事达新材料有限公司 | Crystallization equipment for solid-liquid separation |
| CN211612710U (en) * | 2019-12-31 | 2020-10-02 | 湖北凌安科技有限公司 | Automatic centrifugal powder making device for raw materials of water reducing agent |
| CN113289372A (en) * | 2021-06-23 | 2021-08-24 | 江苏派克斯特纤维素有限公司 | Evaporative crystallization device for processing non-edible salt |
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| Publication number | Publication date |
|---|---|
| CN114669258B (en) | 2024-05-14 |
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