CN114668006A - Biological disinfectant based on natural tartaric acid and preparation process thereof - Google Patents
Biological disinfectant based on natural tartaric acid and preparation process thereof Download PDFInfo
- Publication number
- CN114668006A CN114668006A CN202210413783.0A CN202210413783A CN114668006A CN 114668006 A CN114668006 A CN 114668006A CN 202210413783 A CN202210413783 A CN 202210413783A CN 114668006 A CN114668006 A CN 114668006A
- Authority
- CN
- China
- Prior art keywords
- parts
- fruit acid
- acid
- extract
- mixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/10—Animals; Substances produced thereby or obtained therefrom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
Abstract
The invention discloses a biological disinfectant based on natural tartaric acid and a preparation process thereof, belonging to the technical field of disinfectants and comprising the following components in parts by weight: 15-20 parts of fruit acid extract, 2-5 parts of chitosan, 3-6 parts of antibacterial peptide, 2-5 parts of acetic acid chloride, 2-5 parts of plant additive, 2-4 parts of glycine, 0.5-2.5 parts of surfactant, 2-5 parts of auxiliary agent and the balance of water. By adding the plant additive into the fruit acid extract, the plant additive and the fruit acid extract can activate the activity of the antibacterial peptide, and the invention has broad-spectrum and efficient disinfection and sterilization effects. The natural fruit acid and plant additive can kill harmful microbe and reduce corrosion pollution to the settled area. The invention extracts the fruit acid at low temperature during processing, reduces the loss of active substances after the temperature of the fruit acid is raised, and ensures the sterilizing treatment effect.
Description
Technical Field
The invention belongs to the technical field of disinfectants, and particularly relates to a biological disinfectant based on natural tartaric acid and a preparation process thereof.
Background
The air contains a plurality of microorganisms which have great influence on the life activities of human beings, viruses in the microorganisms breathed by the human beings enter the human bodies along with the air, physiological changes or pathological changes of different degrees can be generated for each human body along with different resistance of each human body, more viruses with drug resistance are discovered by people along with the development of medical science and technology, the viruses with stronger viability generally need to be disinfected by using a disinfectant, and the disinfectant is used for killing pathogenic microorganisms on a transmission medium to meet the harmless requirement, killing the pathogenic microorganisms outside the human bodies, cutting off the transmission path of infectious diseases and achieving the purpose of controlling the infectious diseases.
The traditional disinfectant generally realizes the disinfection treatment of viruses through self toxicity, but the disinfectant generally has certain toxicity, irritation and corrosivity, is easy to influence the environment and has certain harm to human bodies. For example, chinese patent document CN201310148425.2 discloses a disinfectant, which comprises an agent a and an agent B, wherein the agent a comprises, by weight: 90-93% of glacial acetic acid, 3-5% of one or two of sulfuric acid and phosphoric acid and the balance of water; the agent B comprises the following components in percentage by weight: 90-93% of hydrogen peroxide, 3-5% of hydroxyethylidene diphosphonic acid, 0.05-0.5% of 8-hydroxyquinoline and the balance of water. The glacial acetic acid, the sulfuric acid, the phosphoric acid and the hydrogen peroxide added in the invention have certain toxicity, irritation and corrosivity to human bodies, and can not well meet the actual treatment requirements.
Disclosure of Invention
The invention aims to: in order to solve the problems of toxicity, irritation and corrosivity of the traditional disinfectant and incapability of well meeting the treatment requirement, a biological disinfectant based on natural fruit acid and a preparation process thereof are provided.
In order to achieve the purpose, the invention adopts the following technical scheme:
a biological disinfectant based on natural fruit acid comprises the following components in parts by weight: 15-20 parts of fruit acid extract, 2-5 parts of chitosan, 3-6 parts of antibacterial peptide, 2-5 parts of acetic acid chloride, 2-5 parts of plant additive, 2-4 parts of glycine, 0.5-2.5 parts of surfactant, 2-5 parts of assistant and the balance of water.
As a further description of the above technical solution:
the fruit acid extract is one or more of lactic acid, citric acid and malic acid.
As a further description of the above technical solution:
the antibacterial peptide comprises lysostaphin and protamine, and the ratio of the lysostaphin to the protamine is 2: 1.
As a further description of the above technical solution:
the plant additive is a medicinal material extracting agent, and the medicinal material comprises folium Artemisiae Argyi, cortex Magnolia officinalis, rhizoma Atractylodis, herba Eupatorii and flos Magnoliae.
As a further description of the above technical solution:
the surfactant is selected from one or more of dodecyl benzene sulfonic acid, lecithin, rhamnolipid, polyoxyethylene castor oil and polyoxyethylene hydrogenated castor oil;
as a further description of the above technical solution:
the auxiliary agent is ethanol and glycerol, and the ratio of the ethanol to the glycerol is 1: 1.
A preparation process of a biological disinfectant based on natural fruit acid specifically comprises the following steps:
1. treating the raw materials, namely fully cleaning the fruit acid extract raw materials, standing to enable water drops on the surface to slide off, fully crushing the fruit acid extract, and keeping for later use;
2. extracting at low temperature, namely conveying the crushed fruit acid extract into a low-temperature extraction kettle, introducing liquid nitrogen, freeze-drying at low temperature, fully freezing the crushed material by the liquid nitrogen, waiting for the crushed material to be heated and melted, and performing ultrasonic emulsification treatment to obtain an extract liquor;
3. mixing materials, namely feeding chitosan, antibacterial peptide, chlorine acetate, glycine, a surfactant, an auxiliary agent and water into a mixing kettle, performing magnetic force on the materials in the mixing kettle, fully mixing, heating and stirring for 15-20min, waiting for temperature reduction and defoaming, feeding prepared extract liquid into the mixing kettle, fully mixing, and keeping for later use;
4. and adding the mixed solution after the mixing is finished into the corresponding plant additive, uniformly stirring and filling. As a further description of the above technical solution:
the preparation method of the plant additive specifically comprises the following steps:
(1) slicing the medicinal materials, fully cleaning the medicinal materials, airing and drying the medicinal materials, and then slicing the medicinal materials and sending the sliced medicinal materials into a fumigating machine;
(2) adding an extraction solvent into a fumigator, standing for precipitation of partial drug properties, fully pressurizing the fumigator, gradually depressurizing for multiple times of fumigation, mixing multiple distilled extracts, and standing to obtain an extract.
As a further description of the above technical solution:
the first pressure of the pressure distillation is 4mpa, and the pressure is reduced to 1mpa in sequence to obtain three times of distillate.
As a further description of the above technical solution:
in summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:
(1) by adding the plant additive into the fruit acid extract, the plant additive and the fruit acid extract can activate the activity of the antibacterial peptide, and the invention has broad-spectrum and efficient disinfection and sterilization effects.
(2) The natural tartaric acid and the plant additive can kill harmful microorganisms and reduce corrosion pollution to a settlement area, and the biological disinfectant based on the natural tartaric acid is safe, non-irritant and non-corrosive.
(3) The invention extracts the fruit acid at low temperature during processing, reduces the loss of active substances after the temperature of the fruit acid is raised, and ensures the sterilizing treatment effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The invention provides a technical scheme that: a biological disinfectant based on natural fruit acid comprises the following components in parts by weight: 15 parts of citric acid extract, 2 parts of chitosan, 3 parts of antibacterial peptide, 2 parts of acetic acid chloride, 2 parts of plant additive, 2 parts of glycine, 0.5 part of dodecylbenzene sulfonic acid, 2 parts of auxiliary agent and water to supplement the balance, wherein the antibacterial peptide comprises lysostaphin and protamine, the ratio of the lysostaphin to the protamine is 2:1, the plant additive is a medicinal material extracting agent, the medicinal material raw materials comprise folium artemisiae argyi, cortex magnoliae officinalis, rhizoma atractylodis, herba eupatorii and flos magnoliae, the auxiliary agent is ethanol and glycerol, and the ratio of the ethanol to the glycerol is 1: 1.
A preparation process of a biological disinfectant based on natural fruit acid specifically comprises the following steps:
1. processing raw materials, namely fully cleaning the citric acid extract raw materials, standing to enable water drops on the surface to slide off, fully crushing the fruit acid extract, and keeping for later use;
2. extracting at low temperature, namely feeding the citric acid extract powder into a low-temperature extraction kettle, introducing liquid nitrogen, performing low-temperature freeze-drying, fully freezing the crushed material by the liquid nitrogen, waiting for the crushed material to be heated and melted, and performing ultrasonic emulsification treatment to obtain an extract liquid;
3. mixing materials, namely feeding chitosan, antibacterial peptide, chlorine acetate, glycine, dodecylbenzene sulfonic acid, an auxiliary agent and water into a mixing kettle, performing magnetic force sufficient mixing on the materials in the mixing kettle, heating and stirring for 15-20min, waiting for temperature reduction and defoaming, feeding prepared extract liquid into the mixing kettle, and keeping for later use after sufficient mixing;
4. and adding the mixed solution after mixing into a plant additive, uniformly stirring and filling.
The preparation method of the plant additive specifically comprises the following steps:
(1) slicing the medicinal materials, fully cleaning the medicinal materials, airing and drying the medicinal materials, and then slicing the medicinal materials and sending the sliced medicinal materials into a fumigating machine;
(2) adding an extraction solvent into a fumigator, standing for precipitation of a part of drug properties, fully pressurizing the fumigator, gradually depressurizing for multiple times of fumigation, mixing multiple extracting solutions obtained by distillation, standing for obtaining an extracting solution, pressurizing for the first time to 4mpa by pressurized distillation, and sequentially depressurizing to 1mpa to obtain three times of distillate.
Example 2
The invention provides a technical scheme that: a biological disinfectant based on natural fruit acid comprises the following components in parts by weight: the antibacterial peptide comprises lysostaphin and protamine, wherein the ratio of the lysostaphin to the protamine is 2:1, the plant additive is a medicinal material extracting agent, medicinal material raw materials comprise folium artemisiae argyi, cortex magnoliae officinalis, rhizoma atractylodis, herba eupatorii and flos magnoliae, the auxiliary agent is ethanol and glycerol, and the ratio of the ethanol to the glycerol is 1: 1.
A preparation process of a biological disinfectant based on natural fruit acid specifically comprises the following steps:
1. treating the raw materials, namely fully cleaning the lactic acid extract raw materials, standing to enable water drops on the surface to slide off, fully crushing the fruit acid extract, and keeping for later use;
2. extracting at low temperature, namely feeding the crushed lactic acid extract into a low-temperature extraction kettle, introducing liquid nitrogen, performing low-temperature freeze-drying, fully freezing the crushed material by the liquid nitrogen, waiting for the crushed material to be heated and melted, and performing ultrasonic emulsification treatment to obtain an extract liquid;
3. mixing, namely feeding chitosan, antibacterial peptide, chlorine acetate, glycine, rhamnolipid, an auxiliary agent and water into a mixing kettle, performing magnetic force on the materials in the mixing kettle, fully mixing, heating and stirring for 15-20min, waiting for temperature reduction and defoaming, feeding prepared extract into the mixing kettle, fully mixing, and keeping for later use;
4. and adding the mixed solution after the mixing into a corresponding plant additive, uniformly stirring and filling.
The preparation method of the plant additive specifically comprises the following steps:
(1) slicing the medicinal materials, fully cleaning the medicinal materials, airing and drying the medicinal materials, and then slicing the medicinal materials and sending the sliced medicinal materials into a fumigating machine;
(2) adding an extraction solvent into a fumigator, standing for precipitation of a part of drug properties, fully pressurizing the fumigator, gradually depressurizing for multiple times of fumigation, mixing multiple distilled liquid, standing for obtaining an extracting solution, pressurizing for the first time to 4mpa by pressurized distillation, and sequentially depressurizing to 1mpa to obtain three times of distillate;
example 3
The invention provides a technical scheme that: a biological disinfectant based on natural fruit acid comprises the following components in parts by weight: malic acid extract 20 parts, 5 parts of chitosan, 6 parts of antibacterial peptide, 5 parts of acetic acid chloride, 5 parts of plant additive, 4 parts of glycine, 2.5 parts of polyoxyethylene castor oil, 5 parts of auxiliary agent, water make up the surplus, the antibacterial peptide includes lysostaphin and protamine, and the ratio of lysostaphin and protamine is 2:1, the plant additive is the medicinal material extractant, and the medicinal material raw materials include folium artemisiae argyi, cortex magnoliae officinalis, rhizoma atractylodis, herba eupatorii and flos magnoliae the addition auxiliary agent is ethanol, glycerine, and ethanol, glycerine ratio are 1: 1.
A preparation process of a biological disinfectant based on natural fruit acid specifically comprises the following steps:
1. treating the raw materials, namely fully cleaning the malic acid extract raw materials, standing to enable water drops on the surface to slide off, fully crushing the tartaric acid extract, and keeping for later use;
2. extracting at low temperature, namely feeding the crushed malic acid extract into a low-temperature extraction kettle, introducing liquid nitrogen, performing low-temperature freeze-drying, fully freezing the crushed malic acid extract by the liquid nitrogen, waiting for the crushed malic acid extract to be heated and melted, and performing ultrasonic emulsification treatment to obtain an extract;
3. mixing materials, namely feeding chitosan, antibacterial peptide, chlorine acetate, glycine, polyoxyethylene castor oil, an auxiliary agent and water into a mixing kettle, performing magnetic force sufficient mixing on the materials in the mixing kettle, heating and stirring for 15-20min, waiting for temperature reduction and defoaming, feeding prepared extract into the mixing kettle, and after sufficient mixing, reserving for later use;
4. and adding corresponding spice into the mixed solution after the mixing is finished, uniformly stirring and filling.
The preparation method of the plant additive specifically comprises the following steps:
(1) slicing the medicinal materials, fully cleaning the medicinal materials, airing and drying the medicinal materials, and then slicing the medicinal materials and sending the sliced medicinal materials into a fumigating machine;
(2) adding an extraction solvent into a fumigator, standing for precipitation of a part of drug properties, fully pressurizing the fumigator, gradually depressurizing for multiple times of fumigation, mixing multiple extracting solutions obtained by distillation, standing for obtaining an extracting solution, pressurizing for the first time to 4mpa by pressurized distillation, and sequentially depressurizing to 1mpa to obtain three times of distillate.
To further verify the technical effect of the biological disinfectant provided by the invention, the inventor tests according to the relevant requirements of the experiment in the technical Specification for disinfection (2002 edition).
1. Sterilization and disinfection effect test
The sterilization and disinfection effect test is carried out by a suspension quantitative method according to the requirements related to the second part 2.1.1 test in the disinfection technical specification (2002 edition), and the test results are shown in the table 1.
TABLE 1 germicidal effectiveness of disinfectants (action time: 10min)
The test result shows that: according to the evaluation regulation (the killing log value of a bacterial propagule is more than or equal to 5, the killing log value of fungi and viruses is more than or equal to 4 and the disinfection is judged to be qualified) of a suspension quantitative sterilization test in 2.1.1 in the disinfection technical specification (2002 edition), when the disinfection action time is 10min, the disinfectant prepared in the embodiment 1-3 has excellent killing effect on staphylococcus aureus, pseudomonas aeruginosa, escherichia coli and candida albicans (fungi) under the concentration of 1: 1000 in the dilution degree, and the evaluation standard of the disinfectant on the qualification of the killing rate is achieved; when the composition is used for treating black variety of Bacillus subtilis and poliovirus, the disinfection and killing effect can be achieved at a dilution ratio of 1: 300.
2. Skin irritation test and acute oral toxicity test
(1) Single skin irritation test
The test result shows that: the disinfectant stock solutions of examples 1 and 3 were non-irritating to new zealand rabbits in a single whole skin test.
(2) Acute oral toxicology test
The test result shows that: during the test on the disinfectant stock solutions of examples 1 and 3, all the test animals did not show significant toxic symptoms and death within the 14-day observation period; acute oral toxicity LD of disinfectant stock solution on SPF-grade KM mice50More than 5000mg/kg BW, which belongs to the actual nontoxic level.
3. Corrosion test of metals
Examples 1-3 were tested for metal corrosion according to the requirements associated with the second part 2.2.4 of the test in the Disinfection Specification (2002 edition) with stainless steel, carbon steel, copper and aluminum as test subjects and the results are given in Table 2.
TABLE 2 Corrosion test of disinfectants on metals (dilution: 1: 100)
The test result shows that: according to the classification standard for metal corrosivity in the second part 2.2.4 of the specification for disinfection (2002), when the disinfectant prepared in examples 1-3 of the present invention is diluted at a dilution of 1: 100, the corrosion rates for stainless steel, carbon steel, copper and aluminum are all less than 0.01mm/a, all of which are the lowest corrosion levels, and are assigned to the essentially non-corrosive levels.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (9)
1. A biological disinfectant based on natural fruit acid is characterized by comprising the following components in parts by weight: 15-20 parts of fruit acid extract, 2-5 parts of chitosan, 3-6 parts of antibacterial peptide, 2-5 parts of acetic acid chloride, 2-5 parts of plant additive, 2-4 parts of glycine, 0.5-2.5 parts of surfactant, 2-5 parts of auxiliary agent and the balance of water.
2. A biological disinfectant based on natural fruit acids according to claim 1, wherein said fruit acid extract is one or more of lactic acid, citric acid and malic acid.
3. The natural fruit acid based biological disinfectant as recited in claim 1, wherein said antimicrobial peptide comprises lysostaphin and protamine, and the ratio of lysostaphin to protamine is 2: 1.
4. The natural fruit acid-based biological disinfectant as claimed in claim 1, wherein the plant additive is a herbal medicine extracting agent, and the herbal medicine raw materials include folium artemisiae argyi, cortex magnoliae officinalis, rhizoma atractylodis, herba eupatorii and flos magnoliae.
5. A natural fruit acid based biological disinfectant as claimed in claim 1, wherein said surfactant is selected from one or more of dodecylbenzene sulfonic acid, lecithin, rhamnolipid, polyoxyethylene castor oil and polyoxyethylene hydrogenated castor oil.
6. The biological disinfectant based on natural fruit acid as claimed in claim 1, wherein said adjuvant is ethanol and glycerol, and the ratio of ethanol to glycerol is 1: 1.
7. The process for preparing a biological disinfectant based on natural fruit acids according to any one of claims 1 to 6, wherein the process comprises the following steps:
(1) treating the raw materials, namely fully cleaning the fruit acid extract raw materials, standing to enable water drops on the surface to slide off, fully crushing the fruit acid extract, and keeping for later use;
(2) extracting at low temperature, namely conveying the crushed fruit acid extract into a low-temperature extraction kettle, introducing liquid nitrogen, performing low-temperature freeze-drying, fully freezing the crushed material by the liquid nitrogen, waiting for the crushed material to be heated and melted, and performing ultrasonic emulsification treatment to obtain an extract liquid;
(3) mixing materials, namely feeding chitosan, antibacterial peptide, chlorine acetate, glycine, a surfactant, an auxiliary agent and water into a mixing kettle, performing magnetic force on the materials in the mixing kettle, fully mixing, heating and stirring for 15-20min, waiting for temperature reduction and defoaming, feeding prepared extract liquid into the mixing kettle, fully mixing, and keeping for later use;
(4) and adding the mixed solution after the mixing is finished into the corresponding plant additive, uniformly stirring and filling. As a further description of the above technical solution.
8. The process for preparing biological disinfectant based on natural fruit acid as claimed in claim 7, wherein said plant additive preparation method comprises the following steps:
(1) slicing the medicinal materials, fully cleaning the medicinal materials, airing and drying the medicinal materials, and then slicing the medicinal materials and sending the sliced medicinal materials into a fumigating machine;
(2) adding an extraction solvent into a fumigator, standing for precipitation of partial drug properties, fully pressurizing the fumigator, gradually depressurizing for multiple times of fumigation, mixing multiple distilled extracts, and standing to obtain an extract.
9. The process for preparing biological disinfectant based on natural fruit acid as claimed in claim 8, wherein said pressure distillation is performed for the first time at 4mpa, and the pressure is reduced to 1mpa to obtain three times of distillate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210413783.0A CN114668006A (en) | 2022-04-19 | 2022-04-19 | Biological disinfectant based on natural tartaric acid and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210413783.0A CN114668006A (en) | 2022-04-19 | 2022-04-19 | Biological disinfectant based on natural tartaric acid and preparation process thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114668006A true CN114668006A (en) | 2022-06-28 |
Family
ID=82078450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210413783.0A Pending CN114668006A (en) | 2022-04-19 | 2022-04-19 | Biological disinfectant based on natural tartaric acid and preparation process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114668006A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115769832A (en) * | 2022-11-01 | 2023-03-10 | 东莞理工学院 | Preparation method and application of nisin nano composite coacervate |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020066118A (en) * | 2001-02-09 | 2002-08-14 | (주) 바이오스킨테크 | Multifunctional natural antimicrobials including chitosan oligosaccharide chelator and natural extract |
| CN102405935A (en) * | 2011-10-28 | 2012-04-11 | 中山市康乃欣生物医疗科技有限公司 | Protamine compounded preparation, preparation method and application thereof |
| CN104524557A (en) * | 2014-12-16 | 2015-04-22 | 杨陈 | Lysostaphin compound disinfection gel |
| CN110946818A (en) * | 2018-09-25 | 2020-04-03 | 元穗生物科技(上海)有限公司 | Natural herbal skin mucosa disinfectant special for private parts of men |
| CN111543441A (en) * | 2020-04-09 | 2020-08-18 | 宁夏乙征生物工程有限公司 | Biological disinfectant |
| CN112438964A (en) * | 2020-11-30 | 2021-03-05 | 威兰德(山东)生物科技有限公司 | Composite antibacterial film spraying agent of lysostaphin and chitosan |
| CN112970752A (en) * | 2021-03-01 | 2021-06-18 | 中国日用化学研究院有限公司 | Environment-friendly efficient surface disinfectant and preparation method thereof |
-
2022
- 2022-04-19 CN CN202210413783.0A patent/CN114668006A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020066118A (en) * | 2001-02-09 | 2002-08-14 | (주) 바이오스킨테크 | Multifunctional natural antimicrobials including chitosan oligosaccharide chelator and natural extract |
| CN102405935A (en) * | 2011-10-28 | 2012-04-11 | 中山市康乃欣生物医疗科技有限公司 | Protamine compounded preparation, preparation method and application thereof |
| CN104524557A (en) * | 2014-12-16 | 2015-04-22 | 杨陈 | Lysostaphin compound disinfection gel |
| CN110946818A (en) * | 2018-09-25 | 2020-04-03 | 元穗生物科技(上海)有限公司 | Natural herbal skin mucosa disinfectant special for private parts of men |
| CN111543441A (en) * | 2020-04-09 | 2020-08-18 | 宁夏乙征生物工程有限公司 | Biological disinfectant |
| CN112438964A (en) * | 2020-11-30 | 2021-03-05 | 威兰德(山东)生物科技有限公司 | Composite antibacterial film spraying agent of lysostaphin and chitosan |
| CN112970752A (en) * | 2021-03-01 | 2021-06-18 | 中国日用化学研究院有限公司 | Environment-friendly efficient surface disinfectant and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115769832A (en) * | 2022-11-01 | 2023-03-10 | 东莞理工学院 | Preparation method and application of nisin nano composite coacervate |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5425944A (en) | Antimicrobial grapefruit extract | |
| CN107996622B (en) | Mosquito repellent containing plant essential oil | |
| CN107105672A (en) | Antimicrobial compositions and method | |
| JP2008534675A (en) | Antibacterial composition containing natural extract, nanosilver, and natural essential oil | |
| CN107028848A (en) | A kind of disinfection solution of disposable hand natural green | |
| CN106619309A (en) | Pet nursing agent and preparation method thereof | |
| CN106538629A (en) | A kind of livestock-raising disinfectant and preparation method thereof | |
| CN111493097A (en) | Collective disinfectant for inhibiting viruses and pathogenic bacteria and preparation method thereof | |
| CN114668006A (en) | Biological disinfectant based on natural tartaric acid and preparation process thereof | |
| CN108541722A (en) | A kind of livestock-raising disinfectant and preparation method thereof | |
| CN111264567A (en) | Sterilization disinfectant, preparation method and application thereof | |
| KR20120050592A (en) | Nano-emulsion composition and preliminary preparation composition for preventing plant disease using plant essential oil and method for producing the same | |
| CN106726871A (en) | Sweet wormwood mosquito-expelling and antipruritic floral water and preparation method thereof | |
| CN106259482A (en) | A kind of Chinese medicinal plant bactericidal composition and preparation method | |
| DE60124776T2 (en) | ANTIMICROBIAL COMPOSITION | |
| CN110973169B (en) | Biological pesticide of raspberry leaf alcohol extract and preparation method thereof | |
| CN112807237B (en) | Cosmetic containing natural bacteriostatic agent | |
| CN104435607A (en) | Chinese herbal medicine skin mucosa disinfectant | |
| CN111543442A (en) | Composite sterilization liquid based on traditional Chinese medicine volatile oil and preparation method thereof | |
| CN101480199B (en) | Pesticide composition containing bamboo vinegar as well as preparation method and use thereof | |
| CN1332605C (en) | High lipid membrane phytoncide contg. | |
| CN112807259B (en) | Safe and nontoxic mosquito-repellent composition and preparation method and application thereof | |
| CN108812707A (en) | One kind killing thrips plant essential oil composition, preparation and its application | |
| KR100456133B1 (en) | Composition of Bactericidal action and Disinfectant | |
| CN111821286B (en) | Liquid invisible mask with broad-spectrum bacteriostasis and preparation method and use method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |