CN114650828B - 药物组合物 - Google Patents

药物组合物 Download PDF

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Publication number
CN114650828B
CN114650828B CN202080064874.7A CN202080064874A CN114650828B CN 114650828 B CN114650828 B CN 114650828B CN 202080064874 A CN202080064874 A CN 202080064874A CN 114650828 B CN114650828 B CN 114650828B
Authority
CN
China
Prior art keywords
sulfate
nasal
sulfated
polysaccharide
chondroitin sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202080064874.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN114650828A (zh
Inventor
藤枝重治
高林哲司
吉田加奈子
渡部英基
藤川昂树
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruho Co Ltd
University of Fukui NUC
Original Assignee
Maruho Co Ltd
University of Fukui NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruho Co Ltd, University of Fukui NUC filed Critical Maruho Co Ltd
Priority to CN202411053759.6A priority Critical patent/CN118976045A/zh
Priority to CN202410519891.5A priority patent/CN118416094A/zh
Publication of CN114650828A publication Critical patent/CN114650828A/zh
Application granted granted Critical
Publication of CN114650828B publication Critical patent/CN114650828B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733—Fructosans, e.g. inulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CN202080064874.7A 2019-09-20 2020-09-18 药物组合物 Active CN114650828B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202411053759.6A CN118976045A (zh) 2019-09-20 2020-09-18 药物组合物
CN202410519891.5A CN118416094A (zh) 2019-09-20 2020-09-18 药物组合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019-170955 2019-09-20
JP2019170955 2019-09-20
PCT/JP2020/035438 WO2021054440A1 (ja) 2019-09-20 2020-09-18 医薬組成物

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN202411053759.6A Division CN118976045A (zh) 2019-09-20 2020-09-18 药物组合物
CN202410519891.5A Division CN118416094A (zh) 2019-09-20 2020-09-18 药物组合物

Publications (2)

Publication Number Publication Date
CN114650828A CN114650828A (zh) 2022-06-21
CN114650828B true CN114650828B (zh) 2024-08-06

Family

ID=74883058

Family Applications (3)

Application Number Title Priority Date Filing Date
CN202080064874.7A Active CN114650828B (zh) 2019-09-20 2020-09-18 药物组合物
CN202411053759.6A Pending CN118976045A (zh) 2019-09-20 2020-09-18 药物组合物
CN202410519891.5A Pending CN118416094A (zh) 2019-09-20 2020-09-18 药物组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN202411053759.6A Pending CN118976045A (zh) 2019-09-20 2020-09-18 药物组合物
CN202410519891.5A Pending CN118416094A (zh) 2019-09-20 2020-09-18 药物组合物

Country Status (10)

Country Link
US (1) US20220347093A1 (https=)
EP (1) EP4032535A4 (https=)
JP (1) JP7313019B2 (https=)
CN (3) CN114650828B (https=)
AU (1) AU2020349263B2 (https=)
BR (1) BR112022003464A2 (https=)
CA (1) CA3154360C (https=)
MY (1) MY206715A (https=)
PH (1) PH12022550661A1 (https=)
WO (1) WO2021054440A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3144752A1 (fr) * 2023-01-10 2024-07-12 Song Huang Utilisation de polysulfate de pentosane pour le traitement de la toux seche

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11335288A (ja) * 1998-05-20 1999-12-07 Maruho Co Ltd アレルギー性疾患の予防または治療薬

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3497209B2 (ja) 1993-08-24 2004-02-16 生化学工業株式会社 硫酸化糖の脱硫酸化方法
JP3512277B2 (ja) 1995-10-05 2004-03-29 有限会社ジーオーメディカルサービス 鼻茸治療・予防剤
JPH10203988A (ja) 1997-01-27 1998-08-04 Meiji Milk Prod Co Ltd 鼻茸および鼻粘膜の浮腫性病変の治療剤
WO2000069917A1 (fr) * 1999-05-18 2000-11-23 Maruho Kabushikikaisha Compositions medicinales destinees a inhiber le systeme kallikreine-kinine ou la phospholipase a¿2?
EP1922076A4 (en) 2005-08-03 2013-01-23 Morria Biopharmaceuticals USE OF LIPID CONJUGATES IN CYSTIC FIBROSIS AND ITS APPLICATIONS
US20140005115A1 (en) * 2005-11-17 2014-01-02 Yissum Research Development Company Lipid conjugates in the treatment of bronchitis
US8859524B2 (en) * 2005-11-17 2014-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Lipid conjugates in the treatment of chronic rhinosinusitis
CA2790682C (en) 2010-03-03 2020-11-24 Neocutis Sa Compositions and methods for the treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds
CN111437387B (zh) 2013-06-21 2024-10-01 赛诺菲生物技术公司 通过施用il-4r拮抗剂治疗鼻息肉症的方法
JP6637587B2 (ja) * 2015-08-04 2020-01-29 ズートツッカー アーゲー 副鼻腔炎に対するイヌリンの予防的使用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11335288A (ja) * 1998-05-20 1999-12-07 Maruho Co Ltd アレルギー性疾患の予防または治療薬

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
鼻息肉患者血清白细胞介素-5、白细胞介素-8、粒细胞-巨噬细胞集落刺激因子和嗜酸性粒细胞水平变化及相关性;赵艾君等;《新乡医学院学报》;第33卷(第2期);第145-147页，尤其是第146页右栏第1段 *

Also Published As

Publication number Publication date
EP4032535A1 (en) 2022-07-27
CN114650828A (zh) 2022-06-21
CA3154360C (en) 2024-01-23
WO2021054440A1 (ja) 2021-03-25
AU2020349263B2 (en) 2023-08-17
CA3154360A1 (en) 2021-03-25
BR112022003464A2 (pt) 2022-05-24
CN118976045A (zh) 2024-11-19
CN118416094A (zh) 2024-08-02
JPWO2021054440A1 (https=) 2021-03-25
US20220347093A1 (en) 2022-11-03
MY206715A (en) 2025-01-03
EP4032535A4 (en) 2023-10-25
JP7313019B2 (ja) 2023-07-24
AU2020349263A1 (en) 2022-04-14
PH12022550661A1 (en) 2023-03-27

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