CN114642763A - Preparation method and application of biomedical hydrogel composite material - Google Patents
Preparation method and application of biomedical hydrogel composite material Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/52—Water-repellants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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Abstract
The invention discloses a preparation method and application of a biomedical hydrogel composite material, and relates to the technical field of medical appliances. The invention comprises the following steps: preparing polyvinyl alcohol hydrogel; preparing hydrogel containing graphene; selecting proper phase-change microcapsules to prepare phase-change hydrogel; preparing hydrogel containing Chinese medicinal liquid; and coating the prepared hydrogels on the high-molecular medical non-woven fabric material layer by layer in sequence. The composite phase-change microcapsule is used for forming a medical polymer bandage capable of being subjected to cold compress or hot compress, has the advantages of simple structure, low cost, convenience in use, multiple functions, economy and environmental friendliness, and is suitable for being used in sports emergency, household temporary nursing and field first aid, so that the functionality of the bandage is improved.
Description
Technical Field
The invention belongs to the technical field of medical appliances, and particularly relates to a preparation method and application of a biomedical hydrogel composite material.
Background
The bandage is a gauze belt for bandaging wound or affected part, is a common medical article, has various types and various bandaging methods, needs to select proper types and bandaging methods according to the wound part, and typical bandage products comprise 100% all cotton plain bandage, spandex elastic bandage and viscose plaster bandage.
The medical bandage is mainly made of cotton cloth, gauze and elastic tape, and the medical bandage mainly has the functions of bandaging, fixing and protecting, but the bandage in the prior art has single function, can only be used for simple bandaging and fixing, and cannot be used for nursing wounds.
Disclosure of Invention
The invention aims to provide a preparation method and application of a biomedical hydrogel composite material, and solves the technical problem that the function of a bandage in the prior art is single.
In order to achieve the purpose, the invention is realized by the following technical scheme:
a preparation method and application of a biomedical hydrogel composite material comprise the following steps:
preparing polyvinyl alcohol hydrogel;
preparing hydrogel containing graphene;
selecting proper phase-change microcapsules to prepare phase-change hydrogel;
preparing hydrogel containing Chinese medicinal liquid;
and coating the prepared hydrogels on the high-molecular medical non-woven fabric material layer by layer in sequence.
Optionally, the preparation method of the polyvinyl alcohol hydrogel comprises the following steps:
s1, soaking polyvinyl alcohol powder in water, heating in a water bath and stirring to obtain a polyvinyl alcohol aqueous solution;
s2, preparing an aldehyde solution and an acid solution;
s3, slowly dropping an aldehyde solution and an acid solution into the polyvinyl alcohol solution, uniformly stirring to form a blended solution, and standing for 0.5-30h to obtain the polyvinyl alcohol hydrogel; wherein the adding amount of the aldehyde solution is controlled to be between 5 and 20 percent of the mass of the polyvinyl alcohol solution; the adding amount of the acid solution is controlled to be 1-20% of the mass of the polyvinyl alcohol solution;
s4, placing the prepared polyvinyl alcohol hydrogel in an oven until the weight is unchanged, wherein the concentration of the polyvinyl alcohol solution is 5-30 wt%; the aldehyde solution is hexanedial, and the concentration is 1-15 wt%; the acid solution is glacial acetic acid, and the concentration is 2-15 wt%; the soaking time is controlled to be 10-24 h; stirring for 2 h; the heating temperature is 40-80 ℃.
Optionally, the preparation method of the hydrogel containing graphene comprises the following steps:
preparing a graphene oxide suspension, mixing graphite with KMnO4, adding a mixed acid solution of sulfuric acid and phosphoric acid, and heating in a water bath;
cooling to room temperature, pouring into ice water containing H2O2 solution, washing after the solution turns golden yellow until the solution cannot be centrifuged, solidifying by ethyl ether, washing by distilled water until Ph is 7, and performing ultrasonic treatment to obtain suspension;
the substrate obtained in S4 was coated with 1: 10 is soaked in the finishing liquid, reacts for 8 to 12 hours at the temperature of between 25 and 60 ℃, and is washed and dried.
Optionally, the preparation method of the hydrogel containing the traditional Chinese medicine liquid comprises the following steps: preparing 5-10 wt% of saffron extract, soaking the base material obtained from S4 in the finishing liquid according to the ratio of 1: 10, reacting at 25-60 ℃ for 6-8 hours, washing and drying.
Use of a biomedical hydrogel composite comprising: the breathable antibacterial film is characterized in that a hydrogel layer containing graphene is attached to the breathable antibacterial film, a phase-change hydrogel layer is attached to the hydrogel layer containing graphene, a hydrogel layer containing traditional Chinese medicine liquid is attached to the phase-change hydrogel layer, the breathable antibacterial film is attached to the hydrogel layer containing traditional Chinese medicine liquid, and a base material is attached to the breathable antibacterial film.
Optionally, the substrate is a single-layer or 3-5-layer polymer medical non-woven fabric.
Optionally, a flame-retardant layer is arranged on the substrate, and a waterproof layer is arranged on the flame-retardant layer, wherein the waterproof layer is a polytetrafluoroethylene layer, and the flame-retardant layer is formed by adhering flame-retardant components.
Optionally, at least one of a wire mesh layer and a sterilization layer is arranged on the base material.
Optionally, the substrate is a fiber surface layer, the fiber surface layer comprises a plurality of polyester yarns which are arranged in a staggered mode, and air holes are formed between the polyester yarns which are arranged in the staggered mode.
The embodiment of the invention has the following beneficial effects:
the medical high-molecular bandage can be subjected to cold compress or hot compress by virtue of the composite phase-change microcapsules, has the advantages of simple structure, low cost, convenience in use, multiple functions, economy and environmental friendliness, and is suitable for use in sports emergencies, household temporary nursing and field first aid, so that the functionality of the bandage is improved.
Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the invention and, together with the description, serve to explain the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic cross-sectional view of a medical nonwoven fabric according to an embodiment of the present invention;
fig. 2 is a schematic front view of a medical nonwoven fabric according to an embodiment of the present invention;
fig. 3 is a flow chart of the preparation of the medical hydrogel according to an embodiment of the present invention.
Wherein the figures include the following reference numerals:
the breathable antibacterial film comprises a breathable antibacterial film 1, a hydrogel layer 2 containing graphene, a phase-change hydrogel layer 3, a hydrogel layer 4 containing traditional Chinese medicine liquid and a breathable antibacterial film 5.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses.
To maintain the following description of the embodiments of the present invention clear and concise, a detailed description of known functions and known components of the invention have been omitted.
Referring to fig. 1-3, in this embodiment, a method for preparing a biomedical hydrogel composite and an application thereof are provided, which includes the following steps:
the preparation method of the polyvinyl alcohol hydrogel comprises the following steps:
s1, soaking polyvinyl alcohol powder in water, heating in a water bath and stirring to obtain a polyvinyl alcohol aqueous solution;
s2, preparing an aldehyde solution and an acid solution;
s3, slowly dropping an aldehyde solution and an acid solution into the polyvinyl alcohol solution, uniformly stirring to form a blended solution, and standing for 0.5-30h to obtain the polyvinyl alcohol hydrogel, wherein the addition amount of the aldehyde solution is controlled to be 5-20% of the mass of the polyvinyl alcohol solution; the adding amount of the acid solution is controlled to be 1-20% of the mass of the polyvinyl alcohol solution;
s4, placing the prepared polyvinyl alcohol hydrogel in an oven until the weight is unchanged, wherein the concentration of the polyvinyl alcohol solution is 5-30 wt%; the aldehyde solution is hexanedial, and the concentration is 1-15 wt%; the acid solution is glacial acetic acid, and the concentration is 2-15 wt%; the soaking time is controlled to be 10-24 h; stirring for 2 h; heating to 40-80 deg.c;
the preparation method of the hydrogel containing graphene comprises the following steps:
preparing a graphene oxide suspension, mixing graphite with KMnO4, adding a mixed acid solution of sulfuric acid and phosphoric acid, and heating in a water bath;
cooling to room temperature, pouring into ice water containing H2O2 solution, washing after the solution turns golden yellow until the solution can not be centrifuged, solidifying by diethyl ether, washing by distilled water until Ph is 7, and performing ultrasonic treatment to obtain suspension;
the substrate obtained in S4 was coated with 1: 10, soaking the mixture in the finishing liquid, reacting for 8 to 12 hours at the temperature of between 25 and 60 ℃, and washing and drying the mixture;
selecting proper phase-change microcapsules to prepare phase-change hydrogel, wherein the cold compress effect adopts Croda Therm (TM) 5, 6.5 and 9.5 of British Poa Daco company, and the phase-change temperatures are respectively 4, 5 and 9 ℃; the hot compress effect adopts Croda Therm 37, 47 and 52 of British Poa Daco, the phase change temperature is 37, 47 and 52 ℃, and the phase change microcapsule is that Croda Therm PCM of British Poa Daco can be directly dissolved in aqueous solution;
the preparation method of the hydrogel containing the traditional Chinese medicine liquid comprises the following steps: preparing 5-10 wt% of saffron extract, soaking the base material obtained from S4 in the finishing liquid according to the ratio of 1: 10, reacting for 6-8 hours at the temperature of 25-60 ℃, washing and drying;
coating the prepared multiple hydrogels on a high polymer medical non-woven fabric material layer by layer in sequence, wherein the thickness of the medical hydrogel is about 0.2-4.0mm, the thickness of the medical non-drying adhesive is about 0.05-0.5mm, a single layer or 3-5 layers of high polymer medical non-woven fabric material (the surface of which is coated with an antibacterial material) is used as a base material, and a plastic film or release paper is used as a protective film.
The medical high-molecular bandage can be subjected to cold compress or hot compress by virtue of the composite phase-change microcapsules, has the advantages of simple structure, low cost, convenience in use, multiple functions, economy and environmental friendliness, and is suitable for use in sports emergencies, household temporary nursing and field first aid, so that the functionality of the bandage is improved.
Use of a biomedical hydrogel composite comprising: ventilative antibiotic membrane 1, the last laminating of ventilative antibiotic membrane 1 has the hydrogel layer 2 that contains graphite alkene, has the phase transition hydrogel layer 3 on the hydrogel layer 2 that contains graphite alkene, and the last laminating of phase transition hydrogel layer 3 has the hydrogel layer 4 that contains the liquid traditional chinese medicine, and the last laminating of hydrogel layer 4 that contains the liquid traditional chinese medicine has ventilative antibiotic membrane 5, and the last laminating of ventilative antibiotic membrane 5 has the substrate.
The base material of this embodiment is a single-layer or 3-5-layer polymer medical nonwoven fabric.
The base material of this embodiment is equipped with fire-retardant layer, is equipped with the waterproof layer on the fire-retardant layer, and wherein, the waterproof layer is the polytetrafluoroethylene layer, and fire-retardant layer has fire-retardant branch adhesion to form. Through the waterproof layer that sets up, enable the bandage and have waterproof impervious function to reduce the outside liquid invasion that is infected with the virus, through the fire-retardant layer that sets up, make the bandage have the deodorant function of fire prevention, the patient of being convenient for toasts and disinfects.
In the present embodiment, at least one of the metal mesh layer and the sterilization layer is provided on the substrate. Through the metal wire net layer that sets up, make the bandage have antistatic function to improve the toughness of bandage, reduced the cracked condition of bandage.
The substrate of this embodiment is the fibre surface course, and the fibre surface course includes a plurality of crisscross dacron silks that set up, is equipped with the bleeder vent between the dacron silk of crisscross setting.
The above embodiments may be combined with each other.
It should be noted that the terms "first," "second," and the like in the description and claims of this application and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used is interchangeable under appropriate circumstances such that the embodiments of the application described herein are capable of operation in sequences other than those illustrated or described herein.
In the description of the present invention, it is to be understood that the orientation or positional relationship indicated by the orientation words such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal" and "top, bottom", etc. are usually based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and in the case of not making a reverse description, these orientation words do not indicate and imply that the device or element being referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore, should not be considered as limiting the scope of the present invention; the terms "inner and outer" refer to the inner and outer relative to the profile of the respective component itself.
Claims (10)
1. A preparation method of a biomedical hydrogel composite material is characterized by comprising the following steps:
preparing polyvinyl alcohol hydrogel;
preparing hydrogel containing graphene;
selecting proper phase-change microcapsules to prepare phase-change hydrogel;
preparing hydrogel containing Chinese medicinal liquid;
and coating the prepared hydrogels on the high-molecular medical non-woven fabric material layer by layer in sequence.
2. The method of claim 1, wherein the polyvinyl alcohol hydrogel is prepared by the steps of:
s1, soaking polyvinyl alcohol powder in water, heating in a water bath and stirring to obtain a polyvinyl alcohol aqueous solution;
s2, preparing an aldehyde solution and an acid solution;
s3, slowly dropping an aldehyde solution and an acid solution into the polyvinyl alcohol solution, uniformly stirring to form a blended solution, and standing for 0.5-30h to obtain the polyvinyl alcohol hydrogel.
And S4, placing the prepared polyvinyl alcohol hydrogel in an oven until the weight is unchanged.
3. The method of claim 2, wherein the method of preparing the graphene-containing hydrogel comprises the steps of:
preparing a graphene oxide suspension, mixing graphite with KMnO4, adding a mixed acid solution of sulfuric acid and phosphoric acid, and heating in a water bath;
cooling to room temperature, pouring into ice water containing H2O2 solution, washing after the solution turns golden yellow until the solution can not be centrifuged, solidifying by diethyl ether, washing by distilled water until Ph is 7, and performing ultrasonic treatment to obtain suspension;
the substrate obtained in S4 was coated with 1: 10 is soaked in the finishing liquid, reacts for 8 to 12 hours at the temperature of between 25 and 60 ℃, and is washed and dried.
4. The method for preparing a biomedical hydrogel composite material as claimed in claim 2, wherein the method for preparing the hydrogel containing the Chinese medicinal solution comprises the following steps: preparing 5-10 wt% of saffron extract, soaking the base material obtained from S4 in the finishing liquid according to the ratio of 1: 10, reacting at 25-60 ℃ for 6-8 hours, washing and drying.
5. Use of a biomedical hydrogel composite comprising: the breathable antibacterial film comprises a breathable antibacterial film (1), wherein a hydrogel layer (2) containing graphene is attached to the breathable antibacterial film (1), a phase-change hydrogel layer (3) is attached to the hydrogel layer (2) containing graphene, a hydrogel layer (4) containing traditional Chinese medicine liquid is attached to the phase-change hydrogel layer (3), a breathable antibacterial film (5) is attached to the hydrogel layer (4) containing the traditional Chinese medicine liquid, and a base material is attached to the breathable antibacterial film (5).
6. The use of a biomedical hydrogel composite according to claim 5 wherein the substrate is a single layer or 3-5 layers of polymeric medical nonwoven.
7. The use of the biomedical hydrogel composite according to claim 5, wherein the substrate is provided with a flame retardant layer, and the flame retardant layer is provided with a waterproof layer, wherein the waterproof layer is a polytetrafluoroethylene layer, and the flame retardant layer is formed by adhering flame retardant components.
8. The use of a biomedical hydrogel composite according to claim 5 wherein the substrate is provided with a wire mesh layer.
9. The use of a biomedical hydrogel composite according to claim 5 wherein the substrate is provided with a biocidal layer.
10. The application of the biomedical hydrogel composite material as claimed in claim 5, wherein the substrate is a fiber surface layer, the fiber surface layer comprises a plurality of interlaced polyester yarns, and air holes are formed between the interlaced polyester yarns.
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| CN202210183632.0A CN114642763A (en) | 2022-02-28 | 2022-02-28 | Preparation method and application of biomedical hydrogel composite material |
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| CN202210183632.0A CN114642763A (en) | 2022-02-28 | 2022-02-28 | Preparation method and application of biomedical hydrogel composite material |
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| CN107913434A (en) * | 2017-11-21 | 2018-04-17 | 深圳大学 | A kind of preparation method of aerogel dressing |
| US20200330641A1 (en) * | 2019-04-17 | 2020-10-22 | Shulan Jiang | Biodegradable graphene oxide biocomposite fibrous membrane, preparation method and uses thereof |
| CN113637183A (en) * | 2021-08-17 | 2021-11-12 | 安徽大学 | Modified graphene-loaded nano-silver/polyvinyl alcohol antibacterial hydrogel and preparation method thereof |
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