CN1146416C - H+、k+-腺苷三磷酸酶抑制剂在制备治疗鼻息肉药物中的用途 - Google Patents

H+、k+-腺苷三磷酸酶抑制剂在制备治疗鼻息肉药物中的用途 Download PDF

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Publication number
CN1146416C
CN1146416C CNB971985847A CN97198584A CN1146416C CN 1146416 C CN1146416 C CN 1146416C CN B971985847 A CNB971985847 A CN B971985847A CN 97198584 A CN97198584 A CN 97198584A CN 1146416 C CN1146416 C CN 1146416C
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CN
China
Prior art keywords
enzyme inhibitor
adenosine triphosphate
treatment
enantiomer
basic salt
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Expired - Fee Related
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CNB971985847A
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English (en)
Chinese (zh)
Other versions
CN1232397A (zh
Inventor
P���ֵ±���
P·林德贝里
-
J·皮纳斯-马索
J·瑟拉-卡尔雷拉斯
J·特罗法斯特
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AstraZeneca AB
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AstraZeneca AB
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Publication of CN1232397A publication Critical patent/CN1232397A/zh
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Publication of CN1146416C publication Critical patent/CN1146416C/zh
Anticipated expiration legal-status Critical
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
CNB971985847A 1996-10-11 1997-10-01 H+、k+-腺苷三磷酸酶抑制剂在制备治疗鼻息肉药物中的用途 Expired - Fee Related CN1146416C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE96037254 1996-10-11
SE9603725A SE9603725D0 (sv) 1996-10-11 1996-10-11 New teatment

Publications (2)

Publication Number Publication Date
CN1232397A CN1232397A (zh) 1999-10-20
CN1146416C true CN1146416C (zh) 2004-04-21

Family

ID=20404214

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB971985847A Expired - Fee Related CN1146416C (zh) 1996-10-11 1997-10-01 H+、k+-腺苷三磷酸酶抑制剂在制备治疗鼻息肉药物中的用途

Country Status (33)

Country Link
EP (1) EP0946175B1 (enExample)
JP (1) JP4100713B2 (enExample)
KR (1) KR100510812B1 (enExample)
CN (1) CN1146416C (enExample)
AR (1) AR008886A1 (enExample)
AT (1) ATE230597T1 (enExample)
AU (1) AU738310B2 (enExample)
BR (1) BR9711896A (enExample)
CA (1) CA2268305C (enExample)
CZ (1) CZ298799B6 (enExample)
DE (1) DE69718347T2 (enExample)
DK (1) DK0946175T3 (enExample)
EE (1) EE04043B1 (enExample)
ES (1) ES2188995T3 (enExample)
HU (1) HUP0000036A3 (enExample)
ID (1) ID23692A (enExample)
IL (1) IL129324A0 (enExample)
IS (1) IS1930B (enExample)
MY (1) MY117918A (enExample)
NO (1) NO321007B1 (enExample)
NZ (1) NZ334786A (enExample)
PL (1) PL190902B1 (enExample)
PT (1) PT946175E (enExample)
RS (1) RS49599B (enExample)
RU (1) RU2197966C2 (enExample)
SA (1) SA97180641B1 (enExample)
SE (1) SE9603725D0 (enExample)
SK (1) SK284252B6 (enExample)
TR (1) TR199900770T2 (enExample)
TW (1) TW568784B (enExample)
UA (1) UA59374C2 (enExample)
WO (1) WO1998016228A1 (enExample)
ZA (1) ZA978842B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
HRP20010119B1 (hr) 1998-08-18 2008-05-31 The Regents Of The University Of California Sprječavanje stvaranja sluzi u dišnim putevima primjenom antagonista egf-r
US7354894B2 (en) 1998-08-18 2008-04-08 The Regents Of The University Of California Preventing airway mucus production by administration of EGF-R antagonists
US6846799B1 (en) * 1998-08-18 2005-01-25 The Regents Of The University Of California Preventing airway mucus production by administration of EGF-R antagonists
KR100692422B1 (ko) * 1999-03-03 2007-03-09 옵티노즈 에이에스 코 내부로 물질을 전달하는 장치
CA2467652A1 (en) * 2001-11-19 2003-05-30 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
JP2005522462A (ja) * 2002-03-14 2005-07-28 アルタナ ファルマ アクチエンゲゼルシャフト 気道疾患の治療のためのプロトンポンプ阻害剤の使用
HRP20041159A2 (en) * 2002-05-07 2005-08-31 Altana Pharma Ag Combination for the treatment of airway disorders
MXPA04011018A (es) * 2002-05-07 2005-01-25 Altana Pharma Ag Nueva combinacion de inhibidores reversibles de la bomba de protones y productos terapueticos para tratar trastornos de las vias respiratorias.
FR2845915B1 (fr) * 2002-10-21 2006-06-23 Negma Gild Utilisation du tenatoprazole pour le traitement du reflux gastro-oesophagien
AU2003293833B2 (en) 2002-12-12 2009-10-01 Covis Pharma B.V. Combination medicament
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
PT1670482E (pt) 2003-09-16 2014-03-12 Takeda Gmbh Utilização de ciclesonida para o tratamento de doenças respiratórias
RU2252025C1 (ru) * 2003-11-28 2005-05-20 Дальневосточный государственный медицинский университет Способ лечения избыточной грануляционной ткани гортани и трахеи
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN104408249B (zh) * 2014-11-24 2017-09-26 广州供电局有限公司 单芯电缆导体热性参数的确定方法及系统
KR101974504B1 (ko) * 2017-04-10 2019-05-03 재단법인 아산사회복지재단 호산구성 비용종 동물모델

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
GB1571629A (en) * 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate

Also Published As

Publication number Publication date
SE9603725D0 (sv) 1996-10-11
TW568784B (en) 2004-01-01
SK284252B6 (sk) 2004-12-01
UA59374C2 (uk) 2003-09-15
ZA978842B (en) 1998-04-14
DE69718347T2 (de) 2003-08-28
CZ298799B6 (cs) 2008-02-06
BR9711896A (pt) 1999-08-24
ATE230597T1 (de) 2003-01-15
DK0946175T3 (da) 2003-03-17
SA97180641B1 (ar) 2005-12-18
IS5021A (is) 1999-04-08
EP0946175B1 (en) 2003-01-08
SK38499A3 (en) 2000-03-13
EE04043B1 (et) 2003-06-16
DE69718347D1 (de) 2003-02-13
IS1930B (is) 2004-05-18
CZ122999A3 (cs) 1999-09-15
MY117918A (en) 2004-08-30
NO321007B1 (no) 2006-02-27
HUP0000036A2 (hu) 2002-05-29
HUP0000036A3 (en) 2003-02-28
ID23692A (id) 2000-05-11
JP4100713B2 (ja) 2008-06-11
YU16399A (sh) 2000-03-21
AU738310B2 (en) 2001-09-13
CN1232397A (zh) 1999-10-20
IL129324A0 (en) 2000-02-17
JP2001508034A (ja) 2001-06-19
KR100510812B1 (ko) 2005-08-31
HK1022848A1 (en) 2000-08-25
KR20000049046A (ko) 2000-07-25
PT946175E (pt) 2003-04-30
PL190902B1 (pl) 2006-02-28
AU4640997A (en) 1998-05-11
NO991619D0 (no) 1999-04-06
ES2188995T3 (es) 2003-07-01
RU2197966C2 (ru) 2003-02-10
WO1998016228A1 (en) 1998-04-23
PL332692A1 (en) 1999-09-27
CA2268305A1 (en) 1998-04-23
NZ334786A (en) 2000-12-22
NO991619L (no) 1999-04-06
RS49599B (sr) 2007-06-04
AR008886A1 (es) 2000-02-23
EE9900118A (et) 1999-10-15
EP0946175A1 (en) 1999-10-06
TR199900770T2 (xx) 1999-06-21
HU0000036D0 (enExample) 2002-05-29
CA2268305C (en) 2006-11-28

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