Automatic drug delivery device based on micro-displacement sensor
Technical Field
The invention belongs to the technical field of drug delivery, and particularly relates to an automatic drug delivery device based on a micro-displacement sensor.
Background
Clinically, when a specific medicine is applied to a severe patient, the administration speed needs to be strictly controlled to ensure uniform and extremely low-speed administration, so that an automatic administration device is required. After the injector is fixed, the tail position of the push rod of the injector changes along with different doses to be injected. The prior automatic drug delivery device needs medical personnel to manually push the drug delivery push head to be contacted with the tail part of the push rod of the injector, and then starts the drug delivery procedure, namely the whole process needs the intervention of the medical personnel, and the full-automatic drug delivery is not realized; if start the procedure of dosing promptly after fixed syringe, the pushing head of dosing still has a section distance apart from syringe push rod afterbody this moment, because of this distance is unknown, for guaranteeing to use medicine safety, if the pushing head of dosing moves with the speed of dosing, just really injects the medicine to the patient internal after moving to and contacting with syringe push rod afterbody, can't accomplish in time to use medicine, delays patient treatment opportunity.
Disclosure of Invention
The invention aims to solve the contradiction between timely medication and strictly controlling the medication speed when a severe patient applies a specific medicine, and provides an automatic medication device, so that a system is quickly started, the medication push head speed is changed to the set medication speed when the distance between the medication push head and an injector push rod reaches a range of several micrometers, the timely medication is met, the medication speed is strictly controlled, and the medication safety is ensured. The invention can realize the automatic measurement of the relative position information between the administration pushing head and the injector pushing rod, and automatically switch the operation speed of the administration pushing head after the distance between the administration pushing head and the injector pushing rod reaches the designated range, thereby improving the administration working efficiency.
The technical solution for realizing the purpose of the invention is as follows: an automatic drug delivery device based on a micro-displacement sensor comprises a base plate, and a motor mounting rack, a linear guide rail, an injector mounting rack, an end point photoelectric switch mounting seat and a zero position photoelectric switch mounting seat which are fixed on the base plate; the injector is fixed on the injector mounting rack, and a measured object of the eddy current sensor is mounted at the tail part of a push rod of the injector; a trapezoidal screw rod stepping motor is fixedly arranged on the motor mounting frame, a ball sliding block is arranged on the linear guide rail, a trapezoidal screw rod sliding seat is coaxially arranged on a trapezoidal screw rod of the stepping motor, and the ball sliding block and the trapezoidal screw rod sliding seat are both connected with a drug delivery pushing head; the zero photoelectric switch mounting seat and the end photoelectric switch mounting seat are sequentially arranged along the direction of pushing and injecting the medicine by the push rod of the injector, and the zero photoelectric switch and the end photoelectric switch are respectively mounted on the zero photoelectric switch mounting seat and the end photoelectric switch mounting seat;
the device is initialized after being electrified, the trapezoidal screw stepping motor is driven to rotate, the medicine feeding pushing head is driven to move towards the direction of the zero photoelectric switch along the linear guide rail through the trapezoidal screw sliding seat and the ball sliding block, and the device is initialized when the medicine feeding pushing head moves to the zero photoelectric switch; when the automatic drug delivery device is started to work, the trapezoidal lead screw stepping motor drives the drug delivery push head to move towards the direction of the push rod of the injector at a speed of V1, a micro-displacement sensor probe arranged in the drug delivery push head detects the distance between the end face of the drug delivery push head and a measured object of an eddy current sensor arranged at the tail part of the push rod of the injector in real time, namely the distance between the end face of the drug delivery push head and the end face of the push rod of the injector, and when the distance reaches a specified range, the drug delivery push head continues to push the push rod of the injector at a speed of V2 required for drug delivery; when the output level of the photoelectric switch at the end point is turned over, the movement direction of the stepping motor of the trapezoidal screw rod is changed, the stepping motor moves to the direction of the zero photoelectric switch at a speed of V1 and finally stops at the zero position, and the device finishes one-time automatic administration; wherein V1> > V2.
Furthermore, the device also comprises a system controller, wherein the system controller comprises a main controller, a user control module, an information display module, a stepping motor driver, a micro-displacement sensor processing board, a voltage comparator and a potentiometer;
the main controller drives the trapezoidal screw rod stepping motor to rotate by controlling the stepping motor driver;
the micro-displacement sensor probe is connected with the micro-displacement sensor processing board, an analog signal output by the micro-displacement sensor processing board is converted into a digital level by a voltage comparator and then enters a main controller, and the comparison voltage of the voltage comparator is adjusted by a potentiometer;
the digital signals output by the zero photoelectric switch and the terminal photoelectric switch directly enter the main controller;
the user control module is used for realizing the control of an operator on the whole device, including starting and starting;
the information display module is used for displaying related data information in the running process according to application requirements;
based on the system controller, when the device is electrified and initialized, the stepping motor controller drives the trapezoidal screw stepping motor to rotate under the control of the main controller; when the distance between the end face of the medicine push head and a measured object of an eddy current sensor arranged at the tail part of the push rod of the injector reaches a specified range, the output level of the voltage comparator is turned over, the main controller identifies the state change of the level, the movement speed of the medicine administration push head is reduced, and the push rod of the injector is pushed at the speed V2 required by medicine administration; when the output level of the photoelectric switch at the end point is turned over, the main controller changes the movement direction of the trapezoidal screw rod stepping motor, moves towards the direction of the zero photoelectric switch at the speed V1 and finally stops at the zero position.
Furthermore, the comparison voltage of the voltage comparator can be set by adjusting the potentiometer according to the distance between the probe end face of the micro displacement sensor and the end face of the drug delivery push head and the sensitivity information of the micro displacement sensor, so that the output level of the voltage comparator is turned over after the distance between the end face of the drug delivery push head and the end face of the push rod of the injector reaches a specified range.
Further, it has vertical direction slot hole as the motor mounting hole to open on the motor mounting bracket, and when trapezoidal lead screw step motor installed, the installation distance of the vertical direction of trapezoidal lead screw step motor was finely tuned to the vertical direction slot hole of accessible to realize that trapezoidal lead screw and linear guide parallel, then the card can not appear when dosing the pushing head and moving along linear guide.
Furthermore, the micro-displacement sensor probe is arranged in a mounting hole in the upper part of the drug delivery push head and is fixed through a locking device capable of being finely adjusted, and a certain distance is reserved between the end face of the micro-displacement sensor probe and the end face of the drug delivery push head.
Furthermore, the device also comprises a stroke blocking piece arranged on the side surface of the drug delivery pushing head, when the stroke blocking piece moves to the zero photoelectric switch or the end photoelectric switch, output signals of the zero photoelectric switch and the end photoelectric switch are changed, and the signals are transmitted to the main controller, so that the initial position and the end position of the motion of the drug delivery pushing head are judged.
Compared with the prior art, the invention has the following remarkable advantages:
1) the medicine can be fully automatically administered without the intervention of medical staff.
2) The automatic medicine feeding device adopts the high-precision non-contact micro-displacement sensor to detect the distance between the medicine feeding pushing head and the injector push rod in real time, and ensures the quick start of the system.
3) The automatic medicine feeding push head can automatically measure the relative position information between the medicine feeding push head and the injector push rod, and the medicine feeding push head can quickly reach the tail part of the injector push rod and switch to the medicine feeding speed aiming at different medicine dosages, so that the medicine feeding safety is ensured while the timely medicine feeding is met.
The present invention is described in further detail below with reference to the attached drawing figures.
Drawings
FIG. 1 is a mechanical block diagram of an embodiment of a micro-displacement sensor based automatic drug delivery device.
Figure 2 is a block diagram of the drive transmission of the drug delivery pusher in one embodiment.
Fig. 3 is a mounting structure diagram of a micro displacement sensor probe embedded in a drug delivery pushing head in one embodiment, wherein, a drawing (a) is a top view, and a drawing (b) is a side view.
FIG. 4 is a diagram of a structure of an object with a micro-displacement sensor embedded in a push rod of an injector in one embodiment.
FIG. 5 is a diagram of the structure of the object to be measured of the syringe plunger glued micro-displacement sensor in one embodiment.
FIG. 6 is a diagram of a structure of a micro-displacement sensor of a syringe plunger sheath in one embodiment.
FIG. 7 is a block diagram showing a system control circuit according to one embodiment.
FIG. 8 is a schematic diagram of the administration process in one embodiment, wherein FIG. (a) is a schematic diagram of the administration process at a velocity V1 and FIG. (b) is a schematic diagram of the administration process at a velocity V2.
Wherein: 1-a substrate; 2-a motor mounting rack; 3-a linear guide rail; 4-a syringe mounting rack; 5-terminal photoelectric switch mounting seat; 6-zero photoelectric switch mounting base; 7-linear guide rail fixing screws; 8-syringe mount set screw; 9-terminal photoelectric switch mounting seat fixing screw; a 10-zero position photoelectric switch mounting seat fixing screw; 11-trapezoidal lead screw stepping motor; 12-mounting screws for the stepping motor; 13-trapezoidal lead screw; 14-trapezoidal lead screw slide seat; 15-ball slide block; 16-administration pushing head; 17-zero photoelectric switch; 18-terminal opto-electronic switch; 19-stroke blocking piece; 20-stroke baffle plate fixing screws; 21-long hole; 22-micro displacement sensor probe; 23-sensor probe fixing screw; 24-micro displacement sensor probe end face; 25-administration pushing head end face; 26-a syringe; 27-injector pushrod; 28-measuring an object by the embedded micro displacement sensor; 29-measured object of the glued joint type micro-displacement sensor; 30-measured object of the accessory type micro displacement sensor; 31-vertically elongated hole.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
It should be noted that, if directional indications (such as up, down, left, right, front, and back … …) are involved in the embodiment of the present invention, the directional indications are only used for explaining the relative position relationship between the components, the motion situation, and the like under a certain posture (as shown in the drawing), and if the certain posture is changed, the directional indications are changed accordingly.
In one embodiment, as shown in fig. 1, an automatic drug delivery device based on a micro-displacement sensor is provided, which comprises a base plate 1, a motor mounting frame 2, a linear guide rail 3, a syringe mounting frame 4, an end photoelectric switch mounting seat 5 and a zero photoelectric switch mounting seat 6. The motor mounting frame 2, the linear guide rail 3, the injector mounting frame 4, the endpoint photoelectric switch mounting seat 5 and the zero position photoelectric switch mounting seat 6 are all fixed on the substrate 1; the injector 26 is fixed on the injector mounting rack 4, and the tail part of the injector push rod 27 is provided with a measured object of the eddy current sensor; the trapezoidal screw stepping motor 11 is fixed on the motor mounting frame 2, the linear guide rail 3 is provided with a ball slide block 15, a trapezoidal screw slide seat 14 is coaxially arranged on a trapezoidal screw 13 of the stepping motor, and the ball slide block 15 and the trapezoidal screw slide seat 14 are both connected with a drug delivery push head 16; the terminal photoelectric switch mounting base 5 and the zero photoelectric switch mounting base 6 on the substrate 1 are respectively provided with a terminal photoelectric switch 18 and a zero photoelectric switch 17. The motor mounting frame 2 is rectangular, a threaded hole is formed in the bottom of the motor mounting frame 2, a through hole is formed in the corresponding position of the base plate 1, and the motor mounting frame 2 is fixed on the base plate 1 through a fixing screw in the back of the base plate 1; the linear guide rail 3 and the injector mounting rack 4 are respectively fixed on the base plate 1 through a linear guide rail fixing screw 7 and an injector mounting rack fixing screw 8; the terminal photoelectric switch mounting base 5 and the zero photoelectric switch mounting base 6 are respectively fixed on the substrate 1 through a terminal photoelectric switch mounting base fixing screw 9 and a zero photoelectric switch mounting base fixing screw 10.
As shown in fig. 2, the trapezoidal lead screw stepping motor 11 is fixed on the motor mounting frame 2 by a stepping motor mounting screw 12. A trapezoidal screw slide seat 14 is coaxially arranged on a trapezoidal screw 13 of the stepping motor, and a ball slide block 15 is arranged on the linear guide rail 3. The ball slide block 15 is fixed with a drug administration push head 16 through a screw, and the trapezoidal screw slide 14 is fixed on the drug administration push head 16 through a screw. When the trapezoidal screw stepping motor 11 rotates, the trapezoidal screw 13 is driven to rotate together, so that the medicine feeding pushing head 16 is driven to reciprocate along the linear guide rail 3 through the trapezoidal screw sliding seat 14.
As shown in fig. 1 and 2, in this embodiment, the zero-position photoelectric switch 17 and the end-point photoelectric switch 18 are respectively fixed on the zero-position photoelectric switch mounting seat 6 and the end-point photoelectric switch mounting seat 5, the stroke blocking piece 19 is mounted on the side surface of the drug delivery pushing head 16 through the stroke blocking piece fixing screw 20, when the stroke blocking piece 19 moves to the zero-position photoelectric switch 17 or the end-point photoelectric switch 18, the output signals of the zero-position photoelectric switch 17 and the end-point photoelectric switch 18 will be inverted, and the signals are sent to the main controller so that the main controller is used for distinguishing the initial position and the end position of the motion of the drug delivery pushing head 16. The lower surface fixing hole of the terminal photoelectric switch mounting seat 5 is a long hole 21, so that the position of the terminal photoelectric switch mounting seat 5 can be conveniently finely adjusted, and the position of finally finishing the administration can be determined during the integral debugging.
As shown in fig. 3 and 4, the micro-displacement sensor probe 22 of the present embodiment is mounted in a mounting hole at the upper part of the drug delivery pusher head 16 and fixed by a sensor probe fixing screw 23 or a similar locking device capable of fine adjustment. The probe end face 24 of the micro displacement sensor is ensured to have a certain distance from the drug delivery push head end face 25 in the installation process, and the probe 22 of the micro displacement sensor is prevented from being damaged due to the fact that the probe end face 24 of the micro displacement sensor directly contacts with the tail of the injector push rod 27 in the drug delivery process. In order to avoid the influence of the material of the administration pushing head 16 on the measurement, the material of the administration pushing head 16 can be selected from non-metallic materials such as PEEK, PTFE, acrylic and the like.
As shown in fig. 4, 5 and 6, in the present embodiment, the syringe 26 is fixed on the syringe mounting rack 4, and the tail of the syringe push rod 27 is provided with the object to be measured by the eddy current sensor in the form of an embedded 28, an adhesive 29 or a fitting 30, and the material can be selected from aluminum alloy, titanium alloy and the like according to the practical application.
As shown in fig. 7, the automatic drug delivery device based on micro displacement sensor according to this embodiment further includes a system controller. The system controller comprises a main controller, a user control module, an information display module, a stepping motor driver, a micro-displacement sensor processing board, a voltage comparator and a potentiometer. The main controller drives the trapezoidal lead screw stepping motor 11 to rotate by controlling the stepping motor driver; the micro-displacement sensor probe 22 is connected with the micro-displacement sensor processing board, an analog signal output by the micro-displacement sensor processing board is converted into a digital level by a voltage comparator and then enters a main controller, and the comparison voltage of the voltage comparator can be adjusted by a potentiometer; the digital signals output by the zero photoelectric switch 17 and the destination photoelectric switch 18 directly enter the main controller; the user control module is used for controlling the whole device by an operator, and comprises functions of starting, starting and the like; and the information display module displays the related information in the running process according to the application requirement.
As shown in fig. 8, in the automatic drug delivery device based on the micro displacement sensor according to the present embodiment, when the system is started, if the drug delivery pushing head 16 is not yet in contact with the injector pushing rod 27, the running speed of the drug delivery pushing head 16 is V1; after the administration pusher 16 is moved into contact with the syringe plunger 27, the system adjusts the speed of the administration pusher 16 to the desired administration rate V2. In general, V1> > V2 improves the operation efficiency of the apparatus.
The working principle of the automatic drug delivery device based on the micro-displacement sensor is as follows: the end point opto-electronic switch mounting 5 is adjusted during installation of the device to ensure that the output level of the end point opto-electronic switch 18 will flip when the syringe plunger 27 reaches the bottom of the syringe 26. After the system is powered on, under the control of the main controller, the trapezoidal screw stepping motor 11 is driven to rotate by the stepping motor controller, and then the dosing pushing head 16 is driven by the trapezoidal screw sliding seat 14 to move along the linear guide rail 3 towards the direction of the zero photoelectric switch 17. When the medicine feeding pushing head 16 moves to the zero position, the stroke blocking piece 19 fixed on the medicine feeding pushing head 16 shields a transmitting and receiving light path of the zero position photoelectric switch 17, the main controller recognizes that the output level of the zero position photoelectric switch 17 is turned over, and stops the trapezoidal screw rod stepping motor 11 from rotating, so that the medicine feeding pushing head 16 stops at the zero position. When the operator presses the start button, the trapezoidal screw stepping motor 11 drives the administration pushing head 16 to move towards the injector pushing rod 27 at a higher speed V1. The micro-displacement sensor probe 22 arranged in the administration pushing head 16 detects the distance between the administration pushing head and the object to be detected of the eddy current sensor arranged at the tail part of the injector pushing rod 27 in real time, and the micro-displacement sensor processing board converts the distance information into a voltage signal and sends the voltage signal to the voltage comparator. The comparison voltage of the voltage comparator can be set by adjusting a potentiometer according to the information such as the distance between the probe end face 24 of the micro-displacement sensor and the administration pushing head end face 25, the sensitivity of the micro-displacement sensor and the like, so that the output level of the comparator is turned over after the distance between the administration pushing head end face 25 and the end face of the push rod of the injector reaches a specified range. The main controller recognizes the level state change and reduces the speed of the administration pusher to push the syringe pusher at the desired rate V2 for administration. When the output level of the end photoelectric switch 18 is turned over, the main controller changes the movement direction of the trapezoidal screw stepping motor 11, moves to the direction of the zero photoelectric switch 17 at a high speed V1, and finally stops at the zero position, so that the system finishes one-time automatic administration. The related information in the whole operation process is displayed by the information display module.
The automatic drug delivery device adopts the high-precision non-contact micro-displacement sensor to detect the distance between the drug delivery push head and the injector push rod in real time, thereby ensuring the quick start of the system. When the distance between the administration pushing head and the injector pushing rod reaches the range of several micrometers, the speed of the administration pushing head is changed to the set administration speed, so that the administration speed is strictly controlled while the requirement of timely administration is met, and the administration safety is ensured.
The above examples are merely illustrative for clarity and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the spirit or scope of the invention.