CN114573680A - Cd137特异性的蛋白 - Google Patents

Cd137特异性的蛋白 Download PDF

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Publication number
CN114573680A
CN114573680A CN202210118268.XA CN202210118268A CN114573680A CN 114573680 A CN114573680 A CN 114573680A CN 202210118268 A CN202210118268 A CN 202210118268A CN 114573680 A CN114573680 A CN 114573680A
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asp
glu
leu
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Chinese (zh)
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M·欣纳
C·罗特
S·奥威尔
A·艾乐斯道夫尔
R·S·贝莱巴
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Pieris Pharmaceuticals GmbH
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Pieris Pharmaceuticals GmbH
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202210118268.XA 2015-05-04 2016-05-04 Cd137特异性的蛋白 Pending CN114573680A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP15166184.0 2015-05-04
EP15166184 2015-05-04
PCT/EP2016/059959 WO2016177762A1 (en) 2015-05-04 2016-05-04 Proteins specific for cd137
CN201680025274.3A CN107820500B (zh) 2015-05-04 2016-05-04 Cd137特异性的蛋白

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201680025274.3A Division CN107820500B (zh) 2015-05-04 2016-05-04 Cd137特异性的蛋白

Publications (1)

Publication Number Publication Date
CN114573680A true CN114573680A (zh) 2022-06-03

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Application Number Title Priority Date Filing Date
CN202210118268.XA Pending CN114573680A (zh) 2015-05-04 2016-05-04 Cd137特异性的蛋白
CN201680025274.3A Active CN107820500B (zh) 2015-05-04 2016-05-04 Cd137特异性的蛋白

Family Applications After (1)

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CN201680025274.3A Active CN107820500B (zh) 2015-05-04 2016-05-04 Cd137特异性的蛋白

Country Status (18)

Country Link
US (2) US11261221B2 (https=)
EP (2) EP3292137B1 (https=)
JP (3) JP6884708B2 (https=)
KR (1) KR102734408B1 (https=)
CN (2) CN114573680A (https=)
AU (1) AU2016258952C1 (https=)
CA (1) CA2980839C (https=)
CL (1) CL2017002767A1 (https=)
DK (1) DK3292137T3 (https=)
ES (1) ES2932425T3 (https=)
IL (1) IL254516B (https=)
MX (1) MX2017014082A (https=)
NZ (1) NZ736560A (https=)
PH (1) PH12017501583B1 (https=)
RU (1) RU2736312C2 (https=)
SG (1) SG11201708339QA (https=)
WO (1) WO2016177762A1 (https=)
ZA (1) ZA201705960B (https=)

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Publication number Publication date
JP7149363B2 (ja) 2022-10-06
MX2017014082A (es) 2018-06-28
US11261221B2 (en) 2022-03-01
US12195503B2 (en) 2025-01-14
AU2016258952A1 (en) 2017-11-09
RU2736312C2 (ru) 2020-11-13
JP6884708B2 (ja) 2021-06-09
PH12017501583A1 (en) 2018-02-05
AU2016258952C1 (en) 2020-12-24
IL254516B (en) 2021-10-31
ES2932425T3 (es) 2023-01-19
PH12017501583B1 (en) 2023-01-20
WO2016177762A1 (en) 2016-11-10
CA2980839C (en) 2024-09-10
NZ736560A (en) 2021-12-24
ZA201705960B (en) 2023-03-29
US20180148484A1 (en) 2018-05-31
DK3292137T3 (da) 2022-10-17
KR20170142200A (ko) 2017-12-27
JP2018515084A (ja) 2018-06-14
EP4177262A1 (en) 2023-05-10
IL254516A0 (en) 2017-11-30
BR112017020426A2 (en) 2018-06-26
RU2017135599A3 (https=) 2019-09-27
KR102734408B1 (ko) 2024-11-27
JP7477905B2 (ja) 2024-05-02
CA2980839A1 (en) 2016-11-10
HK1249527A1 (en) 2018-11-02
EP3292137A1 (en) 2018-03-14
CN107820500B (zh) 2022-03-01
US20220144901A1 (en) 2022-05-12
CL2017002767A1 (es) 2018-07-20
CN107820500A (zh) 2018-03-20
SG11201708339QA (en) 2017-11-29
JP2022177231A (ja) 2022-11-30
EP3292137B1 (en) 2022-09-07
AU2016258952B2 (en) 2020-08-27
JP2021097695A (ja) 2021-07-01
RU2017135599A (ru) 2019-06-04

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