CN114569184A - Plugging instrument for human body cavity - Google Patents

Plugging instrument for human body cavity Download PDF

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Publication number
CN114569184A
CN114569184A CN202210174247.XA CN202210174247A CN114569184A CN 114569184 A CN114569184 A CN 114569184A CN 202210174247 A CN202210174247 A CN 202210174247A CN 114569184 A CN114569184 A CN 114569184A
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CN
China
Prior art keywords
plugging
diameter
adjusting
wire
bracket
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210174247.XA
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Chinese (zh)
Inventor
刘奕彤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Hiscal Medical Technology Co ltd
Original Assignee
Guangdong Hiscal Medical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Hiscal Medical Technology Co ltd filed Critical Guangdong Hiscal Medical Technology Co ltd
Priority to CN202210174247.XA priority Critical patent/CN114569184A/en
Publication of CN114569184A publication Critical patent/CN114569184A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/1204Type of occlusion temporary occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/1215Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable or resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0007Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting length
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/001Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting a diameter

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention relates to a plugging device used in a human cavity, which comprises: the plugging bracket can be stretched and changed in size, and provides mechanical support for the whole plugging device; adjusting the diameter and drawing a wire, adjusting and positioning the plugging bracket, and fixing the size of the plugging bracket; the sealing film surrounds the plugging bracket to seal and seal the airflow or liquid in the cavity; the plugging support is formed by encircling a plurality of supporting rods connected to the end part of the diameter-adjusting drawing wire, the diameter-adjusting drawing wire is provided with a drawing diameter-adjusting sheet, the outer edge of the drawing diameter-adjusting sheet is attached to the supporting rods of the plugging support, the position of the drawing diameter-adjusting sheet is adjusted, and the outer diameter of the plugging support is changed. The plugging device for the human body cavity disclosed by the invention can adjust the outer diameter and is suitable for different human body cavities caused by individual differences; the plugging device is suitable for cavities with different diameters and shapes, and can achieve an ideal plugging effect.

Description

Plugging instrument for human body cavity
Technical Field
The invention relates to the field of medical instruments, in particular to a plugging instrument for a human body cavity.
Background
In clinical operation treatment, doctors often need to perform blocking operation on certain body cavities to block gas or liquid fluid from passing through, balloon catheters can be used for temporary blocking, but no effective and reliable method is available for medium-long-term blocking, for example, emphysema patients need to block diseased trachea to prevent airflow from continuously flowing into diseased regions to further deteriorate the disease.
Blocking products in the market are generally products with standard specifications produced by manufacturers, for example, aiming at cavities with diameters of 6mm, 7mm, 8mm or 9mm, however, the cavities of human bodies are different due to individual differences of human bodies, and parts of the cavities are not regular circles and have unevenness or ellipses, so that the existing products are difficult to adapt to the cavities with different sizes and shapes.
Meanwhile, the anchoring material of the existing implanted plugging product is a metal non-degradable material, once the implanted plugging product is anchored, the plugging device is difficult to take out, and operations such as emphysema and the like for performing plugging operations need to be taken out after the plugging is finished for a period of time, and once the implanted plugging product is anchored and taken out, the existing implanted plugging product can seriously damage the body cavity and cause hemorrhage or embolism, thereby bringing serious complications to patients.
Disclosure of Invention
In order to overcome the problems, the invention provides a plugging device for human body cavities, which can adjust the outer diameter and is suitable for different human body cavities caused by individual difference; the plugging device is suitable for cavities with different diameters and shapes, and can achieve an ideal plugging effect. And the plugging device is provided with a drug coating to protect the intima of the cavity from causing inflammatory reaction or forming granulation, so that the plugging device is convenient to take out after treatment.
The technical scheme adopted by the invention for solving the technical problems is as follows: an occlusion device for use in a body lumen, comprising: the plugging bracket can be stretched and changed in size, and provides mechanical support for the whole plugging device; adjusting the diameter and drawing a wire, adjusting and positioning the plugging bracket, and fixing the size of the plugging bracket; the sealing film surrounds the plugging bracket for sealing and sealing the airflow or liquid in the cavity; the plugging support is formed by encircling a plurality of supporting rods connected to the end part of the diameter-adjusting drawing wire, the diameter-adjusting drawing wire is provided with a drawing diameter-adjusting sheet, the outer edge of the drawing diameter-adjusting sheet is attached to the supporting rods of the plugging support, the position of the drawing diameter-adjusting sheet is adjusted, and the outer diameter of the plugging support is changed.
Preferably, the diameter-adjusting drawing wire is provided with a plurality of diameter-adjusting drawing wire buckles adapted to the drawing wire diameter-adjusting sheets.
Preferably, the device further comprises a blocking one-way valve which is a one-way opening and closing control device and is used for controlling the one-way outflow of the air flow or the liquid.
Preferably, the blocking support is made of elastic metal and can continuously provide stable supporting force in the human body cavity.
Preferably, the material used for the occluding stent is nitinol or elastic stainless steel.
Preferably, the occlusion device further comprises an anchoring structure for mechanically securing the occlusion device within the lumen to prevent displacement of the occlusion device under pressure.
Preferably, the anchoring structure is arranged on the outer side of the plugging support.
Preferably, the anchoring structure is arranged on the bottom side.
Preferably, the outer surface of the plugging device is provided with a drug coating layer, so that the friction force and the contact surface between the covering film and the wall of the human body cavity channel are improved, and the inflammatory reaction is prevented.
Preferably, the occlusion device is loaded with paclitaxel by a spray or dip coating process.
The invention has the beneficial effects that: a blocking instrument for human body cavity channel can block liquid or gas in human body cavity channel, and the whole blocking instrument is pressed and held into a conveying conduit in the operation process, so that the skeleton and anchoring structure of the blocking instrument can be effectively prevented from damaging the human body cavity channel in the conveying process. Under the guide of endoscope, the catheter enters into the treatment area, the plugging device is pushed out of the catheter by pushing guide wire in the catheter, the plugging device is opened by self-expansion, the plugging diameter can be continuously and steplessly adjusted by adjusting the diameter and wire drawing disc, and the coated film has super elasticity by adding toughening agent, and can adapt to the cavities with different diameters and shapes. The contact surface of the plugging device and the lumen inner membrane can be improved by drilling a hole on the plugging framework and carrying medicine and coating the surface of the covering membrane, inflammatory reaction or endothelialization by the lumen inner membrane is avoided, the anchoring structure is made of degradable metal materials, the anchoring structure can be slowly degraded along with the rehabilitation of a patient, when the plugging device needs to be taken out, the plugging device is held by the biopsy forceps under the guidance of the endoscope, the endoscope is pushed forwards, the plugging device is slowly loaded into the lumen of the endoscope, and finally the plugging device is taken out along with the endoscope, so that the lumen of a human body is prevented from being damaged.
Drawings
The invention is further illustrated by the following examples in conjunction with the drawings.
FIG. 1 is a schematic structural diagram of an occlusion device for use in a body lumen according to embodiment 1 of the present invention;
FIG. 2 is a schematic structural diagram of an occlusion device for use in a body lumen according to embodiment 2 of the present invention;
FIG. 3 is a schematic structural diagram of an occlusion device for use in a body lumen according to embodiment 3 of the present invention;
FIG. 4 is a schematic structural diagram of an occlusion device for use in a body lumen according to embodiment 4 of the present invention;
figure 5 is a schematic top view of the occluding device used in a body lumen of a human body of the present invention.
Wherein, 1: adjusting the diameter and drawing; 2: adjusting the diameter of the wire drawing buckle; 3: plugging the stent; 4: an anchoring structure; 5: plugging the one-way valve; 6: a one-way valve shaft; 7: the retaining piece is opened and closed by the one-way valve; 8: wire drawing and diameter adjusting sheets; 9: sealing the film; 10: a drug coating; 31: a support base; 32: hollowing out the channel; 33: mounting hole
Detailed Description
The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic views illustrating only the basic structure of the present invention in a schematic manner, and thus show only the constitution related to the present invention.
Example 1
An occlusion device for use in a body lumen as shown in figure 1; the device comprises: the plugging support 3 is formed by encircling a plurality of supporting rods connected to the end part of the diameter-adjusting drawing wire 1, in the embodiment, the other end of each supporting rod is connected with a sliding sleeve (not shown), the sliding sleeve is sleeved at the other end of the diameter-adjusting drawing wire 1, so that the plugging support 3 forms an extensible lantern-shaped structure, and the diameter-adjusting drawing wire 1 is provided with a plurality of diameter-adjusting drawing wire buckles 2 adaptive to the drawing wire diameter-adjusting sheets 8, wherein the diameter-adjusting drawing wire buckles 2 are in a circular table-shaped structure, the bottom is a platform, the side part is an inclined hammer-shaped surface, so that the drawing wire diameter-adjusting sheets 8 can only move downwards in the adjusting process, and the structure is more reliable.
As shown in fig. 5, in the embodiment, fig. 5 is a schematic top sectional view, an end portion of the plugging support 3 has a support base 31, a mounting hole 33 is formed in a middle portion of the support base 31, the diameter-adjusting drawn wire 1 is mounted in the mounting hole 33 in the middle portion of the support base 31, and a plurality of hollow channels 32 are further formed between the support base 31 and the mounting hole, so that air or liquid can be introduced into the hollow channels. The plugging one-way valve 5 is fixed at the outer side end of the bracket seat 31, is connected or adhered in a sealing way by a buckle and is communicated with the hollow channel 32.
In the embodiment, the blocking bracket is made of superelastic nickel-titanium alloy materials, shaping and shape keeping are convenient, the bracket is umbrella-shaped, the blocking device is pressed and held in the conveying catheter in the operation process, after the blocking device reaches a target position, the pushing wire is used for ejecting the blocking device, the blocking bracket is opened and attached to the cavity wall, if the blocking bracket is not fully attached to the cavity, the diameter-adjusting wire drawing 1 is pulled through biopsy forceps, the diameter-adjusting wire drawing buckle 8 is pushed downwards, when the diameter-adjusting wire drawing buckle 8 is clamped into the diameter-adjusting wire drawing buckle 2, and the blocking bracket is further opened when the diameter-adjusting wire drawing buckle 8 moves towards the lower end, so that the effect of continuously adjusting the blocking bracket is realized, and the blocking bracket is better attached to the cavity. The diameter-adjusting wire drawing buckle 8 is used for adjusting the diameter of the plugging support so that the plugging support can be better attached to the cavity.
In this embodiment, the anchoring structure 4 is disposed on the beam of the plugging support 3, i.e. on the supporting rod, when the plugging support 3 is unfolded, the anchoring structure 4 is fastened on the cavity wall, the plugging support 3 is fixed on the cavity wall, and the plugging support 3 is prevented from moving in the cavity channel, wherein, the anchoring structure 4 is in the shape of a plurality of elastic supporting rods with hooks, one end is attached to the supporting rod of the plugging support 3, after the plugging support 3 is taken out, the anchoring structure 4 can fall off, and the anchoring structure 4 is made of degradable magnesium alloy or iron alloy, and after the plugging treatment is finished, the anchoring structure is naturally degraded, so that a doctor can conveniently take out the plugging apparatus, and avoid scratching the cavity channel. The sealing film 9 is covered on the plugging support, the material is one or a plurality of polyurethane, nylon or latex materials, the sealing film is used for sealing airflow or liquid in the cavity, the plugging one-way valve 5 is used for a one-way opening and closing control device and controlling the airflow or the liquid to flow out in a one-way mode, the medicine coating 10 is coated on the outer surface, the material is the composite of polyvinylpyrrolidone, heparin and nano silver ions, and the phenomenon that the coating is adhered to or has inflammatory reaction with the inner skin of the cavity is avoided.
Example 2
As shown in fig. 2, the present embodiment is different from embodiment 1 in that: the anchoring structure 4 in this embodiment is arranged at the tail end of the occlusion stent 3, the anchoring structure 4 is an umbrella-shaped structure with a plurality of open rods, and the end part is provided with a bulge towards the side part.
Example 3
As shown in fig. 3, the present embodiment is different from embodiment 1 in that: the plugging support 3 is formed by encircling a plurality of supporting rods connected to the end part of the diameter-adjusting drawing wire 1, one end of the plugging support is connected to the end part of the diameter-adjusting drawing wire 1, and the other end of the plugging support is of an open structure, so that the whole plugging device forms an umbrella-shaped structure. As shown in fig. 5, in this embodiment, fig. 5 is a schematic top view, an end portion of the plugging support 3 has a support base 31, a mounting hole 33 is formed in a middle portion of the support base 31, the diameter-adjusting drawn wire 1 is mounted in the mounting hole 33 in the middle portion of the support base 31, and a plurality of hollow channels 32 are further formed between the support base 31 and the mounting hole, so as to allow air or liquid to pass through. The plugging one-way valve 5 is fixed at the outer side end of the bracket seat 31, is connected by a buckle or is adhered in a sealing way, and is communicated with the hollow channel 32.
Example 4
As shown in fig. 4, the present embodiment is different from embodiment 3 in that: the anchoring structure 4 in this embodiment is disposed at the rear end of the plugging support 3 and is attached to the end of the plugging one-way valve 5, the anchoring structure 4 and the plugging one-way valve 5 are not fixedly attached to each other and are detachably attached to each other, when the plugging support 3 is taken out, the anchoring structure 4 is separated, the anchoring structure 4 is an umbrella-shaped structure with a plurality of struts open, and the end has a protrusion toward the side.
The blocking instrument in the cavity can block liquid or gas in the human cavity, and the whole blocking instrument is pressed and held into the conveying catheter in the operation process, so that the framework and the anchoring structure of the blocking instrument can be effectively prevented from damaging the human cavity in the conveying process. Under the guide of an endoscope, the catheter enters a treatment area, the plugging device is pushed out of the catheter by pushing a guide wire in the catheter, the plugging device is opened by self expansion, the plugging diameter can be continuously and steplessly adjusted by a diameter adjusting wire drawing disc, the toughening agent added into the covering film has superelasticity and can adapt to the lumens with different diameters and shapes, and the problems that the diameter of the traditional plugging device is fixed to be a plurality of specifications and cannot be well matched with the diameter of the lumen, when the diameter of the plugging device is small, plugging is not tight, the plugging device is displaced, when the diameter of the plugging device is large, the intima is damaged by over expansion, and when the intima of the plugging lumen is uneven, the wall adhesion cannot be well realized are avoided. The contact surface of the plugging device and the lumen inner membrane can be improved by drilling a hole on the plugging framework and carrying medicine and coating the surface of the covering membrane, inflammatory reaction or endothelialization by the lumen inner membrane is avoided, the anchoring structure is made of degradable metal materials, the anchoring structure can be slowly degraded along with the rehabilitation of a patient, when the plugging device needs to be taken out, the plugging device is held by the biopsy forceps under the guidance of the endoscope, the endoscope is pushed forwards, the plugging device is slowly loaded into the lumen of the endoscope, and finally the plugging device is taken out along with the endoscope, so that the lumen of a human body is prevented from being damaged.
In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.

Claims (10)

1. An occlusion device for use in a body lumen, comprising: the blocking device comprises a blocking bracket which can be stretched and changed in size to provide mechanical support for the whole blocking device;
adjusting the diameter and drawing a wire, adjusting and positioning the plugging bracket, and fixing the size of the plugging bracket;
the sealing film surrounds the plugging bracket to seal and seal the airflow or liquid in the cavity;
the plugging support is formed by encircling a plurality of supporting rods connected to the end part of the diameter-adjusting drawing wire, the diameter-adjusting drawing wire is provided with a drawing diameter-adjusting sheet, the outer edge of the drawing diameter-adjusting sheet is attached to the supporting rods of the plugging support, the position of the drawing diameter-adjusting sheet is adjusted, and the outer diameter of the plugging support is changed.
2. An occlusion device for use in a body lumen as claimed in claim 1, wherein: the diameter-adjusting wire drawing is provided with a plurality of diameter-adjusting wire drawing buckles adapted to the wire drawing diameter-adjusting sheets.
3. An occlusion device for use in a body lumen according to claim 2, wherein: the device also comprises a plugging one-way valve which is a one-way opening and closing control device and is used for controlling the one-way outflow of air flow or liquid.
4. An occlusion device according to claim 3, characterised in that: the plugging bracket is made of elastic metal and can continuously provide stable supporting force in a human body cavity.
5. An occlusion device for use in a body lumen as claimed in claim 4, wherein: the occluding stent is formed from nitinol or a resilient stainless steel.
6. An occlusion device for use in a body lumen as claimed in claim 3, wherein: the blocking instrument also comprises an anchoring structure, and the blocking instrument is fixed in the cavity, so that the blocking instrument is prevented from displacing under pressure.
7. An occlusion device according to claim 6, characterised in that: the anchoring structure is arranged on the outer side of the plugging support.
8. An occlusion device according to claim 6, characterised in that: the anchoring structure is arranged on the bottom side.
9. An occlusion device for use in a body lumen as claimed in claim 6, wherein: the outer surface of the plugging device is provided with a drug coating layer, so that the friction force and the contact surface between the covering film and the wall of the human body cavity canal are improved, and inflammatory reaction is prevented.
10. An occlusion device for use in a body lumen as claimed in claim 9, wherein: and carrying out drug loading by adopting a process of spraying or dip-coating the plugging device with paclitaxel.
CN202210174247.XA 2022-02-24 2022-02-24 Plugging instrument for human body cavity Pending CN114569184A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210174247.XA CN114569184A (en) 2022-02-24 2022-02-24 Plugging instrument for human body cavity

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Application Number Priority Date Filing Date Title
CN202210174247.XA CN114569184A (en) 2022-02-24 2022-02-24 Plugging instrument for human body cavity

Publications (1)

Publication Number Publication Date
CN114569184A true CN114569184A (en) 2022-06-03

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115634004A (en) * 2022-12-26 2023-01-24 北京久事神康医疗科技有限公司 Tumor internal filling device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080262518A1 (en) * 2006-10-05 2008-10-23 Franz Freudenthal Implantable device
CN105658148A (en) * 2013-06-26 2016-06-08 W.L.戈尔及同仁股份有限公司 Occlusive device
CN107233146A (en) * 2016-09-21 2017-10-10 沛嘉医疗科技(苏州)有限公司 It is applicable heart bicuspid valve and tricuspid valve band valve support replacement valve
US20190021741A1 (en) * 2015-12-29 2019-01-24 Shenzhen Kyd Biomedical Tehcnology Co. Ltd. Left atrial appendage closure apparatus
CN209827099U (en) * 2019-02-22 2019-12-24 北京大学深圳研究生院 Amplitude-adjustable rotary type ventricular isolation device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080262518A1 (en) * 2006-10-05 2008-10-23 Franz Freudenthal Implantable device
CN105658148A (en) * 2013-06-26 2016-06-08 W.L.戈尔及同仁股份有限公司 Occlusive device
US20190021741A1 (en) * 2015-12-29 2019-01-24 Shenzhen Kyd Biomedical Tehcnology Co. Ltd. Left atrial appendage closure apparatus
CN107233146A (en) * 2016-09-21 2017-10-10 沛嘉医疗科技(苏州)有限公司 It is applicable heart bicuspid valve and tricuspid valve band valve support replacement valve
CN209827099U (en) * 2019-02-22 2019-12-24 北京大学深圳研究生院 Amplitude-adjustable rotary type ventricular isolation device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115634004A (en) * 2022-12-26 2023-01-24 北京久事神康医疗科技有限公司 Tumor internal filling device

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Application publication date: 20220603

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