CN104771203B - Blood vessel cleaning device - Google Patents

Blood vessel cleaning device Download PDF

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Publication number
CN104771203B
CN104771203B CN201510107428.0A CN201510107428A CN104771203B CN 104771203 B CN104771203 B CN 104771203B CN 201510107428 A CN201510107428 A CN 201510107428A CN 104771203 B CN104771203 B CN 104771203B
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China
Prior art keywords
pipe unit
layer pipe
blood vessel
cleaning device
wall
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Expired - Fee Related
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CN201510107428.0A
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Chinese (zh)
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CN104771203A (en
Inventor
陈明惠
范云平
李�昊
张姣
徐花卉
陈珍
严华
陈志雄
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University of Shanghai for Science and Technology
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University of Shanghai for Science and Technology
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Priority to CN201510107428.0A priority Critical patent/CN104771203B/en
Publication of CN104771203A publication Critical patent/CN104771203A/en
Application granted granted Critical
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Expired - Fee Related legal-status Critical Current
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Abstract

The invention provides a blood vessel cleaning device. The blood vessel cleaning device is provided with a main body support part, a rotating shaft part and a cleaning part, wherein the main body support part comprises an inner-layer pipe unit, an intermediate pipe unit and an outer-layer pipe unit which are arranged in a concentric circle; the rotating shaft part is in screw connection with the inner-layer pipe unit and used for driving the inner-layer pipe unit to rotate; the cleaning part is used for cleaning sediments and comprises a cleaning brush arranged on the outer wall of the outer-layer pipe unit; the rotating shaft part extends outside; a plurality of balls are arranged on the intermediate pipe unit; one end of each ball is fit with the outer wall of the inner-layer pipe unit, and the other end of each ball is fit with the inner wall of the outer-layer pipe unit; and the inner-layer pipe unit drives the outer-layer pipe unit to rotate through the balls to further drive the cleaning brush to rotate so as to clean sediments in an intravascular stent. The blood vessel cleaning device can conveniently remove thrombi deposited on the intravascular stent, and a patient only needs to clean the stent periodically along with radiography, so that not only is convenience brought for the daily life, but also troubles caused by long-term medicine taking and physical injuries caused by side effects of medicines are avoided.

Description

A kind of blood vessel cleaning device
Technical field
The invention belongs to medical instruments field, and in particular to a kind of blood vessel cleaning device.
Background technology
Minimally invasive (minimally invasive), as the term suggests, it is exactly small wound, wound, is modern medicine surgery The characteristics of operative treatment application, microtrauma is only caused exactly in surgical procedure to patient, postoperative small wound is left behind The technology of mouth, is the scientific and technological achievement of relatively conventional operation.Minimally invasive is the word being specially connected with operation and surgery, such as minimally invasive Operation, minimally invasive surgery etc..It is minimally invasive that mainly there are four big advantages:Otch is little, wound is little, recovery is fast, pain is few.
The maturation of minimal invasive techniques creates the generation of stent-expansion iatrotechnics of depositing for blood vessel, and stent in the treatment art is now such as The modern optimal treatment method for blood vessel alluvial, support can release the hemadostewnosis of lesion, improve CBF and reach Alleviate the therapeutic purposes of human body ischemic.Common intravascular stent is the metal tube of various sizes of hollow out, as illustrated, which rises propping up The effect of support vascular wall, can release the narrow of lesion completely.Intravascular stent is attached to after being folded on the sacculus of retraction, by leading The conveying of pipe induction system, Jing femoral artery or trans-radial, conduit is sent at coronary ostium along arteries trend, then Guiding steel wire is delivered to into the coronary artery distal end of pathology along conduit, is finally that support is delivered to blood vessel coronarius along steel wire is narrow Narrow lesion;Then balloon expandable, intravascular stent is made gradually to recover tubular structure during balloon expandable with compression pump pressurization; Finally reduce pressure, sacculus is taken out, support retains there.
After metallic blood vessel bracket is successfully used to clinical treatment, second challenge is how to overcome human body to support " attack ".Originally, support was treated as foreign matter by body, and impingement is treated as at the position that support and artery film are contacted.There are wound, people Body will be repaired to which.Then, inflammatory reaction just occurs at the support of artery.Many patients especially diabetes patient, Occur serious scar tissue hyperplasia around metallic support, this scar tissue hyperplasia, it is serious in the case of can cause smooth The artery for having led to is again narrow, or even blocking.If after stenter to implant, patient fails to adhere to medication, does not change bad life Mode living, blood pressure, blood fat, glycemic control obtain undesirable, and normal blood vessel may produce new pathology, support portions originally It is likely to ISR occur.But intravascular stent once implants, just carried by patient throughout one's life, it is impossible to take out again.So, in advance The secondary alluvial of anti-support becomes a very important thing.
In order to reduce support postoperative restenosis, conventional method is at present:Patient need to uninterruptedly take medicine Existing hemadostewnosis, but long-time medication, not only bother but also can bring injury for patient body function.Second generation overlay film frame be by Medicine and support are combined together, i.e., in one layer of medicine film of metal support surface " plating ", after this stenter to implant body is interior, medicine is just Can slowly release, suppress scar tissue in support surrounding growth, keep coronary artery unobstructed.Although overlay film frame is certain The probability of postoperative secondary blocking is reduced in degree, but the medicine on overlay film frame can exhaust eventually, and the uncontrollability of medicine The therapeutic effect of overlay film frame is significantly limit, so, the secondary blockage problem after stenter to implant is still present.
The content of the invention
The present invention is carried out for solving the above problems, and by providing a kind of blood vessel cleaning device, will can be deposited in blood Thrombus that is on inside pipe wall and depositing on intravascular stent is removed.
Present invention employs following technical scheme:
The blood vessel cleaning device that the present invention is provided, with such technical characteristic, has:Main body rack portion, including with same The internal layer pipe unit of heart circle formula arrangement, middle pipe unit and outer layer pipe unit;Shaft, shaft and internal layer pipe unit spiral shell Connection is closed, for driving inner tube finite element rotation;And cleaning section, for clearing up drift, including being arranged at outer layer pipe unit Cleaning brush on outer wall.Wherein, shaft stretches out in vitro, is provided with a plurality of balls on middle pipe unit, one end of ball and The outer wall of internal layer pipe unit fits, and the inwall of the other end and outer layer pipe unit fits, and internal layer pipe unit is driven by ball Outer tube finite element rotation, and then drive cleaning brush rotation, the drift cleared up in intravascular stent.
The blood vessel cleaning device that the present invention is provided, can also have the feature that, also include:Expansion supporting part, including Structure is identical and is arranged at the first expansion supporting part on middle pipe unit outer wall and the second expansion supporting part with preset space length, For strutting vascular wall.Expansion supporting part includes the umbrella support being arranged on middle pipe unit outer wall and is covered in umbrella Filter membrane on frame, for intercepting drift.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:Umbrella support is by shape-memory material Prepare, recover shape in the presence of blood heat and launch, it is micro- to strut vascular wall.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:Middle pipe unit stretches out in vitro, can edge Axially with respect to internal layer pipe unit and the movement of outer layer pipe unit, for adjusting the position of expansion supporting part.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:Cleaning section also includes being arranged at outer layer Groove on pipe unit outer wall, and the bracing wire matched with groove and cleaning brush, bracing wire are used for controlling the lifting of cleaning brush.Clearly Clean brush is positioned in groove, and including the brush body that width ratio recess width is smaller, and one end is embedded in the bristle on brush body top.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:Divide on the outer wall of groove rear and front end Contour and the first cylinder with annular space is not provided with, the number of the first cylinder is 4, and the rear and front end of brush body is distinguished The second cylinder of annular space is provided with, the number of the second cylinder is 2.
In same one end of cleaning section, the second cylinder is located between two the first cylinders, and the position of the second cylinder Less than the first cylinder.One end of bracing wire is fixed in the annular space of one of them the first cylinder, and the other end is successively through second The lower end of the annular space of cylinder, the upper edge of the annular space of another the first cylinder, finally by being arranged on outer layer pipe unit The gap that through hole is entered between middle pipe unit and outer layer pipe unit, is brought out outside blood vessel cleaning device.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:Outer layer pipe unit and inner tube list The length of unit is 30~60mm, and the internal diameter of outer layer pipe unit is 2~6mm, and the internal diameter of internal layer pipe unit is 1~4mm, cleaning brush Length be 30~60mm, thickness be 1~2mm.
The blood vessel cleaning device that the present invention is provided, can also have the feature that:The outer wall of shaft carries external screw thread, The inwall of internal layer pipe unit carries internal thread, and internal layer pipe unit is matched by external screw thread and internal thread, in the band for rotating axle portion Dynamic lower rotation.
Further, present invention also offers a kind of blood vessel cleaning device remove Ink vessel transfusing drift method, including with Lower step:
Step one, blood vessel cleaning device under the protection of outer layer flexible conduit, and under the guiding of guiding catheter and seal wire, At intravasation alluvial;
Step 2, promotes middle pipe unit so that the first expansion supporting part and the second expansion supporting part are respectively enterd clearly It is in the blood of clean brush both sides, micro- to strut vascular wall;
Step 3, pulls bracing wire so that cleaning section rises, rotating shaft portion so that cleaning section in internal layer pipe unit and Rotate under the drive of outer layer pipe unit, remove drift.
Step 4, cleaning device is exited in vitro.
Invention effect and effect
The invention provides a kind of blood vessel cleaning device, with main body rack portion, including with concentric circles arrangement Layer pipe unit, middle pipe unit and outer layer pipe unit;Shaft, shaft and internal layer pipe unit are screwed together, for driving Inner tube finite element rotation;And cleaning section, for clearing up drift, including the cleaning brush being arranged on outer layer pipe unit outer wall, Shaft stretches out in vitro, and the outer wall for being provided with a plurality of balls, one end of ball and internal layer pipe unit on middle pipe unit is affixed Close, the inwall of the other end and outer layer pipe unit fits, internal layer pipe unit drives outer tube finite element rotation, and then band by ball Dynamic cleaning brush rotation, the drift cleared up in intravascular stent.Blood vessel cleaning device during this law is bright, can be by using the strength of machinery Endovascular thrombus and the drift deposited on intravascular stent are easily removed, and patient is only needed periodically with radiography cleaning support , both facilitated daily life and turn avoid the injury of the trouble and drug side-effect of Long-term taking medicine to body.
Description of the drawings
Fig. 1 is the top view of the blood vessel cleaning device of the present invention;
Fig. 2 is the front view of the blood vessel cleaning device of the present invention;
Fig. 3 be the present invention Fig. 2 in Section A-A structural representation;
Fig. 4 is the structural representation of the shaft of the present invention;
Fig. 5 is the structural representation of the blood vessel cleaning device of the expansion supporting part in stretch-like of the present invention;
Fig. 6 is the structural representation of the blood vessel cleaning device that the cleaning brush of the present invention stretches out;
Fig. 7 is the structural representation of the cleaning section of the present invention;
Fig. 8 is the method stream of the secondary drift produced after the blood vessel cleaning device of the present invention removes intravascular stent iatrotechnics Cheng Tu.
Specific embodiment
The specific embodiment of the present invention is illustrated below in conjunction with accompanying drawing.
Fig. 1 is the top view of the blood vessel cleaning device of the present embodiment.
Fig. 2 is the front view of the blood vessel cleaning device of the present embodiment.
Fig. 3 is the structural representation of the Section A-A in Fig. 2 of the present embodiment.
Fig. 4 is the structural representation of the shaft of the present embodiment.
As shown in Figures 1 to 4, blood vessel cleaning device 100 include main body rack portion 1, expansion supporting part 2, cleaning section 3 and Shaft 4, main body rack portion 1 is by the outer layer pipe unit 11 arranged with concentric circles, middle pipe unit 12 and inner tube list Unit 13 constitutes, and expansion supporting part 2 and middle pipe unit 12 connect, and cleaning section 3 is located in outer layer pipe unit 11, shaft and internal layer Pipe unit 13 connects.
A plurality of balls 121, one end of ball 121 and inner tube is provided with middle pipe unit 12 in main body rack portion The outer wall of unit 13 fits, and the inwall of the other end and outer layer pipe unit 11 fits;Carry on the inwall of internal layer pipe unit 13 On internal thread, and shaft 4, set external screw thread 41 matches, and cooperation of the internal layer pipe unit 13 by screw thread, in shaft 4 Drive under rotate, then drive outer layer pipe unit 11 to rotate by steel ball 121.The inwall of outer layer pipe unit 11 and inner tube Processed using frosted with the position of ball contact on the outer wall of unit 13, with the friction between increase and ball so that outer tube The driven rotation of unit 11 preferably can be driven.Meanwhile, middle pipe unit 12, can be axially with respect to by ball 121 Internal layer pipe unit 13 and outer layer pipe unit 11 are moved, to adjust the position of expansion supporting part 2.
Structural representations of the Fig. 5 for the blood vessel cleaning device of the expansion supporting part in stretch-like of the present embodiment.
As shown in figure 5, expansion supporting part 2 includes that structure is identical and is arranged on 12 outer wall of middle pipe unit with preset space length The first expansion supporting part 21 and the second expansion supporting part 22, the first expansion supporting part 21 and the second 22 points of supporting part of expansion The both sides vertically of cleaning section 4 are not arranged at.During first expansion supporting part 21 or the second expansion supporting part 22 include being surrounded on Between umbrella stull on 12 outer wall of pipe unit and the macromolecular filter membrane being covered on the umbrella stull, to allow normal blood flow to lead to Cross, and will be filtered by the solid particle such as the patch for coming off or the thrombus for being formed, so as to protect downstream blood vessel not to be blocked.
Umbrella support is prepared by medical shape-memory material, such as Nitinol, under conditions of less than blood heat, umbrella Support can be with arbitrary shape docile on the outer wall of middle pipe unit 12, and under conditions of blood heat, umbrella support can recover Shape, starts to surrounding to stretch, micro- to strut vascular wall.Umbrella support also can be prepared by elastomeric macromolecular material, utilize which Elastic reaction, it is micro- to strut vascular wall.
Fig. 6 is the structural representation of the blood vessel cleaning device that the cleaning brush of the present embodiment stretches out.
Fig. 7 is the structural representation of the cleaning section of the present embodiment.
As shown in Fig. 3, Fig. 6 and Fig. 7, cleaning section 3 is located in outer layer pipe unit 11, can be rotated with outer layer pipe unit 11. Cleaning section 3 includes the groove 31 being arranged in 11 wall of outer layer pipe unit, and the cleaning brush 32 that is positioned in groove 31 and draws Line, cleaning brush 32 can be lifted under the control of bracing wire.Cleaning brush 32 include the smaller brush body of width ratio recess width and The bristle on the embedded brush body top in one end, for removing the drift on vascular wall or intravascular stent.
Contour and the first cylinder 311 with annular space 3111 is respectively arranged with the outer wall of 31 rear and front end of groove, The number of the first cylinder 311 is four, and both sides respectively have two;The rear and front end of brush body is respectively provided with annular space 3211 Two cylinders 321, the number of the second cylinder 321 is two, and both sides are each one.
In same one end, the second cylinder 321 is located between two the first cylinders 311, and the position of the second cylinder 321 Less than the first cylinder 311.One end of bracing wire is fixed in the annular space 3111 of one of them the first cylinder 311, other end elder generation Afterwards through the lower end of the annular space 3211 of the second cylinder 321, the upper edge of the annular space 3111 of another the first cylinder 311, finally Gap between middle pipe unit 12 and outer layer pipe unit 11 is introduced into by through hole 111, blood vessel cleaning is then brought out Outside device.
Pull the other end of the bracing wire of cleaning section axial direction both sides, cleaning brush 32 rise in the presence of bracing wire, loosen Bracing wire, cleaning brush 32 are down in groove.
In the present embodiment, middle pipe unit 12, shaft 4 and bracing wire are extend out in vitro, in order to operation device.Outward The length of layer pipe unit 11 and internal layer pipe unit 13 is 30~60mm, and the internal diameter of outer layer pipe unit is 2~6mm, inner tube The internal diameter of unit is 1~4mm, and the length of cleaning brush is 30~60mm, and thickness is 1~2mm.
Blood vessel cleaning device in the present embodiment, the removing for being not only suitable for Intravascular Thrombus are treated suitable for intravascular stent again The removing of the secondary drift of postoperative generation.As the endovascular thrombus of non-implantable intravascular support is removed, also can select and take Thrombolytic drug rushes other more easily methods such as blood vessel and carries out thrombolysis, and these methods are for prevention or remove after implantation support Secondary drift generation, drawback is more, therefore, after this assembly first is used for implantable intravascular support, the secondary alluvial of Ink vessel transfusing The removing of thing.
Under by taking the removing of the secondary drift produced after based on intravascular stent iatrotechnics as an example, specifically with intracranial vessel support As a example by the secondary cleaning of thrombus at place, the method that the blood vessel cleaning device in the present embodiment removes Ink vessel transfusing drift is illustrated.For It is easy to description, below description has used term " near-end " and " distal end ", wherein " near-end " refers to the one end close to operating side, " distal end " refers to the one end away from operating side.
The side of the secondary drift that Fig. 8 is produced after removing intravascular stent iatrotechnics for the blood vessel cleaning device in the present embodiment Method flow chart.
As shown in figure 8, the method for the secondary drift produced after blood vessel cleaning device removing intravascular stent iatrotechnics, with clear As a example by except drift at intracranial vessel support, comprise the steps:
Step one, patient is applied general anaesthetic or continuous epidural anesthesia after, clinostatism of making even carries out radiography to intracranial vessel, Determine lesion locations;
Step 2, by 6F guiding catheters, 0.35, " under the guiding of superslide seal wire, head end imports blood vessel from femoral artery or arteria brachialis It is interior, then shown by angiogram, guide via microtubular, blood vessel cleaning device is sent to into occlusion near-end at support, its In, blood vessel cleaning device is under the protection of outer layer flexible conduit at intravasation support;
Step 3:After ready, intermediate conductor unit is promoted, cleaning brush is released into outer layer flexible conduit, when its distal end is entered When entering the distal end of Ink vessel transfusing intravascular stent, the expansion supporting part at cleaning brush two ends is respectively enterd in the blood at cleaning brush two ends, umbrella Shape support is progressively opened due to the elastic reaction of the SME or high resiliency macromolecular material of shape memory metal, micro- Strut vascular wall;
Step 4:By the pulling of bracing wire so that the second cylinder and be located at two first cylinders of the same side with which Concordantly, and fixed bracing wire, now, the miniature cleaning brush of strip at the bus of side is just drawn out outer layer pipe unit, is exposed to blood In;
Step 5, pulls shaft, makes cleaning brush clockwise or counterclockwise, be close to cradle wall and slowly rotate, instead After multiple operation for several times, the cleaning of intravascular stent is completed;
Step 6, after cleaning is complete, unclamps fixed bracing wire first, brushhead portion is returned in outer layer pipe unit, Then pipe unit in the middle of pulling so that cleaning section, expansion supporting part, outer layer pipe unit and internal layer pipe unit integrally return to outer In layer conveying flexible conduit, pull flexible conduit which is exited outside blood vessel along the track of superslide seal wire, finally exit superslide seal wire, it is whole Individual thrombus removing work is finished.
Above step is equally applicable to the blood vessel cleaning device of suitable dimension and removes the silt at other Ink vessel transfusing intravascular stents The secondary cleaning of product thing, is equally applicable to the removing of endovascular thrombus before non-implantable intravascular support.
The effect of embodiment and effect
A kind of blood vessel cleaning device is present embodiments provided, with main body rack portion, including what is arranged with concentric circles Internal layer pipe unit, middle pipe unit and outer layer pipe unit;Expansion supporting part is identical including structure and be arranged at preset space length The first expansion supporting part and the second expansion supporting part on the middle pipe unit outer wall, for strutting vascular wall;Shaft, It is screwed together with internal layer pipe unit, for driving inner tube to rotate;And cleaning section, for clearing up endovascular drift, bag Include the groove being arranged on internal layer pipe unit outer wall, the cleaning brush being positioned in groove and match with groove and cleaning brush Bracing wire, for controlling the lifting of cleaning brush, wherein, on middle pipe unit, be provided with a plurality of balls, one end and inner tube list The outer wall of unit fits, and the inwall of the other end and outer layer pipe unit fits, and middle pipe unit, can be axially opposed by ball Move in internal layer pipe unit and outer layer pipe unit, outer layer pipe unit is rotated under the drive of internal layer pipe unit by ball, and then Cleaning brush rotation is driven, endovascular drift is cleared up.Blood vessel cleaning device in the present embodiment, can be by using the strength of machinery Endovascular thrombus and the drift deposited on intravascular stent are easily removed, and patient is only needed periodically with radiography cleaning support , both facilitated daily life and turn avoid the injury of the trouble and drug side-effect of Long-term taking medicine to body.
The invention is not restricted to the scope of specific embodiment, for those skilled in the art, as long as respectively Kind of change described claim limit and the spirit and scope of the present invention that determine in, these changes be it will be apparent that All are using the innovation and creation of present inventive concept in the row of protection.

Claims (8)

1. a kind of blood vessel cleaning device, for the secondary drift produced after clearing up intravascular stent iatrotechnics, it is characterised in that bag Include:
Main body rack portion, including the internal layer pipe unit arranged with concentric circles, middle pipe unit and outer layer pipe unit;
Shaft, the shaft and the internal layer pipe unit are screwed together, for driving the inner tube finite element rotation;And
Cleaning section, for clearing up the drift, including the cleaning brush being arranged on the outer layer pipe unit outer wall,
Wherein, the end of the shaft extends in vitro,
The outer wall for being provided with a plurality of balls, one end of the ball and the internal layer pipe unit on the middle pipe unit is affixed Close, the inwall of the other end and the outer layer pipe unit fits,
The internal layer pipe unit drives the outer tube finite element rotation by the ball, and then drives the cleaning brush rotation, The drift cleared up in the intravascular stent.
2. blood vessel cleaning device according to claim 1, it is characterised in that also include:
Expansion supporting part, including structure it is identical and with preset space length be arranged on the middle pipe unit outer wall first expansion Support part and the second expansion supporting part, for strutting vascular wall,
The expansion supporting part includes the umbrella support being arranged on the middle pipe unit outer wall and is covered in the umbrella Filter membrane on support, the filter membrane are used for intercepting the drift.
3. blood vessel cleaning device according to claim 2, it is characterised in that:
Wherein, the umbrella support is prepared by shape-memory material, and the umbrella support recovers shape in the presence of blood heat Shape launches, micro- to strut the vascular wall.
4. blood vessel cleaning device according to claim 2, it is characterised in that:
The middle pipe unit stretches out in vitro, can move axially with respect to the internal layer pipe unit and the outer layer pipe unit, For adjusting the position of the expansion supporting part.
5. blood vessel cleaning device according to claim 1, it is characterised in that:
Wherein, the cleaning section also includes being arranged at groove on the outer layer pipe unit outer wall, and with the groove and institute The bracing wire that cleaning brush matches is stated,
The cleaning brush is positioned in the groove, and including the brush body that recess width described in width ratio is smaller, and one end is embedded in The bristle on the brush body top,
The bracing wire is used for controlling the lifting of the cleaning brush.
6. blood vessel cleaning device according to claim 5, it is characterised in that:
Wherein, contour and the first cylinder with annular space is respectively arranged with the outer wall of the groove rear and front end, it is described The number of the first cylinder is 4, and the rear and front end of the brush body is respectively provided with the second cylinder with annular space, described second The number of cylinder is 2,
In same one end of the cleaning section, second cylinder is located between two first cylinders, and described second The position of cylinder is less than first cylinder,
One end of the bracing wire is fixed in the annular space of one of them first cylinder, and the other end is successively through described second The lower end of the annular space of cylinder, the upper edge of the annular space of another first cylinder, finally by being arranged at The gap that the through hole on outer layer pipe unit is entered between the middle pipe unit and the outer layer pipe unit is stated, institute is brought out State outside blood vessel cleaning device.
7. blood vessel cleaning device according to claim 1, it is characterised in that:
Wherein, the length of the outer layer pipe unit and the internal layer pipe unit is 30~60mm, the outer layer pipe unit Internal diameter is 2~6mm, and the internal diameter of the internal layer pipe unit is 1~4mm,
The length of the cleaning brush is 30~60mm, and thickness is 1~2mm.
8. blood vessel cleaning device according to claim 1, it is characterised in that:
Wherein, the outer wall of the shaft carries external screw thread, and the inwall of the internal layer pipe unit carries internal thread, the inner tube Unit is matched by the external screw thread and the internal thread, is rotated under the drive of the shaft.
CN201510107428.0A 2015-03-11 2015-03-11 Blood vessel cleaning device Expired - Fee Related CN104771203B (en)

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CN104771203B true CN104771203B (en) 2017-03-22

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Publication number Priority date Publication date Assignee Title
CN108578023B (en) * 2018-04-25 2020-03-24 广西中医药大学 Graphene oxide heart blood vessel stent and preparation method thereof

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CN102573670A (en) * 2009-10-16 2012-07-11 心血管系统股份有限公司 Eccentric abrading and cutting head for high-speed rotational atherectomy devices
CN103717156A (en) * 2011-08-12 2014-04-09 W.L.戈尔及同仁股份有限公司 Systems for removal of atherosclerotic plaque or thrombus at a treatment site
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CN202397550U (en) * 2011-11-17 2012-08-29 祖茂衡 Clearer of thrombus in stent

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