CN106994204A - Double sacculus medicine-coated balloon dilating catheters - Google Patents
Double sacculus medicine-coated balloon dilating catheters Download PDFInfo
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- CN106994204A CN106994204A CN201710221352.3A CN201710221352A CN106994204A CN 106994204 A CN106994204 A CN 106994204A CN 201710221352 A CN201710221352 A CN 201710221352A CN 106994204 A CN106994204 A CN 106994204A
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- Prior art keywords
- sacculus
- chamber
- balloon
- push rod
- work
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
- A61M29/02—Dilators made of swellable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Abstract
The invention discloses a kind of pair of sacculus medicine-coated balloon dilating catheter, including push rod;The push rod distal end is respectively fixed with the work sacculus for adhering to medication coat and the occlusion balloon for blocking blood flow;Guidewire lumen, for being filled to work sacculus first full chamber and the second full chamber for being filled to occlusion balloon for being used to install seal wire are provided with the push rod, first full chamber and work balloon lumen UNICOM, the second full chamber and occlusion balloon inner chamber UNICOM.The present invention using double sacculus, on the one hand reduce blood flow to the scouring effect of medicine, reduce medicine and come off, on the other hand do not increase conduit diameter size, reduce operating difficulty and surgical injury.
Description
Technical field
The invention belongs to technical field of medical instruments, it is related to a kind of dilating catheter, more particularly to a kind of pair of sacculus medicine is applied
Layer sacculus dilating catheter.
Background technology
Narrow arteries is the class disease for perplexing the mankind all the time, in order to be passed through after curing this kind of disease, mankind elder generation
The treatment stages such as bare ball capsule, bare bracket, drug stent are gone through, the defect of various therapeutic schemes also exposes in follow-up practice
Come.Then medicine eluting balloon catheter arises at the historic moment, and it avoids the risk that in-stent restenosis is caused after implantation support, not only
It is that blood fortune sets up passage by balloon expandable, and the medicine that is loaded with of sacculus can effectively suppress the hyperplasia of smooth muscle cell and prevent
Hemostatic tube ISR.
Common single saccule conduit outer wall carries medicine in the prior art, as shown in figure 1, be a kind of single saccule conduit, medicine is defeated
Diseased region is sent to be expanded, but this medicine eluting balloon catheter has about more than 50% in course of conveying in the blood vessels
Medicine washed away and lost by quick artery blood flow, wherein the moment that about 30% medicine is opened in sacculus, blood vessel diameter
Do not reach 1 with balloon expandable diameter:When 1, the blood flow quickly flowed is washed away.These medicines lost do not only exist blocking
The risk of distal vessels, and these medicines being washed can increase the metabolism burden of body.
The improvement of prior art, mainly also on single saccule medicinal balloon catheter, certain effect is played in improvement, but still
In the presence of many problems, for example with the inner surface coating in sacculus flap, to avoid medicinal balloon catheter from passing in the blood vessels
Drug loss in journey, so incomplete load prescription formula of balloon surface, which does not only exist diseased region, can not receive effective treatment
The risk of medicine, and it is not avoided that sacculus can not reach 1 in expansion moment and sacculus with vascular wall diameter:Blood is to medicine when 1
Thing washes away.
It is to use many sacculus to also have a kind of improved procedure in addition, is respectively provided in the work sacculus both sides for carrying medicine few two
Blood vessel is blocked after distal balloon catheter and proximal balloon, distal balloon catheter and proximal balloon bulging, chamber is formed between two sacculus, adopts
Had the following disadvantages with the foley's tube of many sacculus:When blocking blood vessel after distal balloon catheter and proximal balloon bulging, in two sacculus
Between form in chamber, and chamber the blood that there is closing, then the blood closed during full work sacculus is nowhere flowed, and influence is expanded
Fill effect or cause balloon dilatation difficult and be likely to cause the damage of blood vessel, while there is also blood coagulation for closed static blood
Risk;Complex operation step, influence blood flow is unobstructed;Multiple full chambers are needed, the diameter of conduit is increased, and then needed to use big
The guiding catheter of diameter causes doctor's operation inconvenience, while also causing the puncturing hole increase at patient's puncture, adds patient's
Pain;There is the foley's tube of multiple sacculus in addition, the area of sacculus and contacts blood is big, and sacculus scratches calcification lesion and narrow
The risk increase of lesion.
The content of the invention
The technical problem to be solved in the present invention is that on the one hand the drawbacks described above for prior art is reduced there is provided a kind of
Blood flow to the scouring effect of medicine, reduce medicine and come off, on the other hand do not increase conduit diameter size, reduce operating difficulty and hand
Double sacculus medicinal balloon catheters of art damage.The technical solution adopted for the present invention to solve the technical problems is:A kind of pair of sacculus
Medicine-coated balloon dilating catheter, including push rod;
The push rod distal end is respectively fixed with the work sacculus for adhering to medication coat and the resistance for blocking blood flow
Fill in sacculus;
The interior guidewire lumen provided with for installing seal wire of the push rod, first for being filled to work sacculus fill
Chamber and the second full chamber for being filled to occlusion balloon, the first full chamber are filled with work balloon lumen UNICOM, second
Chamber and occlusion balloon inner chamber UNICOM.
In described double sacculus medicine-coated balloon dilating catheters, preferably described work sacculus is arranged on occlusion balloon near-end
In the push rod of side, or the work sacculus is arranged in the push rod of occlusion balloon distal end side.
In described double sacculus medicine-coated balloon dilating catheters, the diameter of preferably described work sacculus is slightly smaller than obstruction ball
Capsule diameter, or the work balloon diameter are identical with occlusion balloon diameter.
In described double sacculus medicine-coated balloon dilating catheters, the active section of preferably described work sacculus is cylinder,
A diameter of 2-15mm, the length of active section is 20-300mm.
In described double sacculus medicine-coated balloon dilating catheters, preferably described occlusion balloon is spherical, or the resistance
It is cylinder, a diameter of 2-20mm to fill in the active section of sacculus.
In described double sacculus medicine-coated balloon dilating catheters, between preferably described work sacculus and occlusion balloon between
Away from for 0-90mm.
In described double sacculus medicine-coated balloon dilating catheters, preferably described push rod near-end is provided with catheter block, described
Catheter block is provided with guidewire port, work balloon dilatation port and occlusion balloon expansion port;
Resistance is provided with the push rod being provided with push rod in work sacculus in the full mouth of work sacculus, the occlusion balloon
Fill in sacculus and fill mouth;
Guidewire port and guidewire lumen UNICOM;
First full chamber two ends difference UNICOM work balloon dilatation port and work sacculus fill mouth;
Second full chamber two ends difference UNICOM's occlusion balloon expansion port and occlusion balloon fill mouth.
In described double sacculus medicine-coated balloon dilating catheters, preferably described work sacculus, occlusion balloon effective length
In the range of corresponding push rod be provided be used for sacculus position development positioner.
In described double sacculus medicine-coated balloon dilating catheters, the multi-lumen tube that preferably described push rod is formed in one,
Push rod is along longitudinal direction provided with guidewire lumen spaced apart from each other, the first full chamber and the second full chamber.
In described double sacculus medicine-coated balloon dilating catheters, preferably described push rod is separable assembled structure;
The push rod includes two-chamber outer tube and inner tube, and said inner tube is sleeved in a tube chamber of two-chamber outer tube, described
The tube chamber of inner tube is guidewire lumen, and two tube chambers of two-chamber outer tube are respectively the first full chamber and the second full chamber;
Or the push rod includes an outer tube and two inner tubes, two inner tubes are sleeved in outer tube side by side, in two
Guan Zhong, inner tube tube chamber is guidewire lumen, and the cavity between another inner tube tube chamber and outer tube and inner tube is respectively first to fill
The chamber and second that is full of fills chamber;
Or the push rod is that three bodys are set with composition successively, central lumen is the cavity between guidewire lumen, three pipes
Respectively first full chamber and the second full chamber.
Washed away to solve the medicine on medicinal balloon catheter in expansion moment by blood, the present invention is using a kind of double
Sacculus medicinal balloon catheter, two sacculus are set in push rod, and one is work sacculus for adhering to medication coat, another
It is the occlusion balloon for blocking blood flow, occlusion balloon is first expanded in use, further expansion works after blocking blood flow
Blood flow can be reduced during work sacculus expansion effect is washed away to work balloon surface medicine after sacculus, blocking blood flow
Should, reduce medicine and come off, so as to increase reprinting rate, and then drugloading rate can be reduced, the poison for mitigating active medicine to normal cell is secondary
Effect and organism metabolism burden;The single blood flow for blocking balloon occlusion flowing will not form closed blood cavity, not interfere with
Work balloon dilatation effect causes balloon dilatation difficult, does not increase the risk of injury of blood vessel, does not increase the risk of blood coagulation;Using
Three cavities conduit pipe structure, it is ensured that the diameter of conduit is consistent with the diameter that common single saccule medicine applies foley's tube, not because conduit is straight
The increase in footpath and the use size for increasing sheath in surgical procedure, do not change doctor's operating habit and operation method, do not increase disease
Probability of the people by wound.
Brief description of the drawings
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing:
Fig. 1 is the operating diagram of single saccule conduit half expansion in the blood vessel of prior art;
Fig. 2 is the structural representation of the embodiment of the present invention;
Fig. 3 is double sacculus medicine-coated balloon dilating catheters of the invention half operating diagram expanded in the blood vessel;
Fig. 4-7 is the structural representation of the integrally formed push rod inner chamber of the embodiment of the present invention 1;
Fig. 8-9 is the structural representation of the push rod inner chamber of the separable assembled of the embodiment of the present invention 2.
Embodiment
In order to which technical characteristic, purpose and effect to the present invention are more clearly understood from, now compare accompanying drawing and describe in detail
The embodiment of the present invention.
Embodiment 1, as illustrated in figs. 2-7, a kind of pair of sacculus medicine-coated balloon dilating catheter, including push rod 3;It is described to push away
The distal end of bar 3 is sent to be respectively fixed with the work sacculus 1 for adhering to medication coat 5 and the occlusion balloon 2 for blocking blood flow;It is described
It is provided with for the guidewire lumen 6 for installing seal wire, for being filled to work sacculus 1 first full chamber 7 and is used in push rod 3
The the second full chamber 8 filled to occlusion balloon 2, the first full chamber 7 and work sacculus 1 inner chamber UNICOM, the second full chamber 8 with
The inner chamber UNICOM of occlusion balloon 2.
The effect one of push rod 3 is to be used to work sacculus 1 pushing to operating position, and another effect is to undertake conveying
The function of pipeline.Work sacculus 1 and occlusion balloon 2 are weldingly fixed in push rod 3, between work sacculus 1 and occlusion balloon 2
Mutual alignment is not construed as limiting, and only need to be both located within the distal end of push rod 3, i.e., described work sacculus 1 is arranged on occlusion balloon 2
In the push rod 3 of near-end side, or the work sacculus 1 is arranged in the push rod 3 of the distal end side of occlusion balloon 2.This reality
Apply in example, work sacculus 1 is located in the push rod 3 of the distal end side of occlusion balloon 2.
Push rod 3 has three function cavitys, and respectively guidewire lumen 6, first fills chamber 7 and second and fills chamber 8, three chambers
Ti Hubu UNICOMs.Realizing the structure of push rod 3 of three function cavitys has a variety of, and one kind is integrally formed multi-lumen tube, another
For separable assembled three function cavitys of formation.It is to use integrally formed multi-lumen tube as shown in figs. 4-7, push rod 3 is set along longitudinal direction
There is guidewire lumen 6, first spaced apart from each other to fill chamber 7 and second and fill chamber 8.The shape of cross section of multi-lumen tube is not construed as limiting, and is only needed
Three functional chamber bodies are spaced from each other, and guidewire lumen 6 is used to install seal wire, and therefore, guidewire lumen 6 needs cavity smooth and shape is sharp
The straight line tube chamber moved in seal wire, the cross section of general guidewire lumen 6 is from shapes such as circular or ellipses, the first full He of chamber 7
The shape of cross section of second full chamber 8 is not construed as limiting, and can be any shape, typically can according to the shape of cross section of push rod 3, lead
The silk location and shape of chamber 6, the first full chamber 7 and second of arrangement the maximum cross-section area fills chamber 8.And the first full He of chamber 7
The quantity of second full chamber 8 is not construed as limiting, and sets quantity can be at 1-3, as shown in Figure 4,5, guidewire lumen 6, first fills chamber 7
One, in Fig. 4 is respectively set with the second full chamber 8, guidewire lumen 6, first fills chamber 7 and second and fills the laid out in parallel of chamber 8, guidewire lumen
6 and first the cross section of full chamber 7 be circle, the second full chamber 8 is semilune.Guidewire lumen 6 is located at the second full chamber 8 in Fig. 5
In, the cross section of guidewire lumen 6 is circle, and the first full chamber 7 is ellipse, and the second full chamber 8 is arc.In Fig. 6, the first full chamber
7 set two, and guidewire lumen 6 and second fills chamber 8 and respectively sets one.In Fig. 7, the second full chamber 8 sets two, the He of guidewire lumen 6
First full chamber 7 sets one.In Fig. 6, the cross section of guidewire lumen 6 is circle, and the first full chamber 7 and second fills chamber 8 not advise
Then shape.In Fig. 7, the cross section of guidewire lumen 6 is circle, and it is arc surfaced that the first full chamber 7 and second, which fills chamber 8,.
As shown in Fig. 2 the both ends of the work sacculus 1 are pyramidal structure, middle active section is cylinder, it is a diameter of
2-15mm, the length of work sacculus 1 is generally 30-320mm, and effective length is that the length of active section is 20-300mm, effectively long
Degree refers to sacculus after full in cylindrical shape, the length played a supportive role in surgical procedure to blood vessel.The table of work sacculus 1
Face is coated with one layer of medication coat 5, and medication coat 5 is mainly disposed to active section.Medication coat 5 can have to suppress smooth muscle
Taxol drug, rapamycin drug of hyperplasia effect etc..The diameter of sacculus 1, the effective length of working select straight according to blood vessel
Footpath is selected.Medication coat 5 is applied to prior art, will not be repeated here.The active section selection cylinder of work sacculus 1, makes
Work sacculus 1 after must filling has good adherence quality, it is possible to have certain length to attach blood vessel, can be effectively by medicine
It is transferred on blood vessel wall.
The occlusion balloon 2 is spherical, or the active section of the occlusion balloon is cylinder, a diameter of 2-20mm.Resistance
The diameter of plug sacculus 2 is similarly selected according to blood vessel diameter.The diameter of the work sacculus 1 is slightly smaller than the diameter of occlusion balloon 2, or
The diameter of sacculus 1 that worked described in person is identical with the diameter of occlusion balloon 2.The diameter of occlusion balloon 2 is slightly larger than work sacculus 1, can cause
Occlusion balloon 2 can in advance expand after apparatus enters diseased region, blocking blood flow.
Spacing between the work sacculus 1 and occlusion balloon 2 is 0-90mm.Work between sacculus 1 and occlusion balloon 2
It can be close to, gap is not stayed therebetween, can also stay at regular intervals, for example:Spacing be 10,15,20,30,35,40,
90mm etc..
The near-end of push rod 3 is provided with catheter block 4, and the catheter block 4 is provided with guidewire port 12, work balloon dilatation port
14 and occlusion balloon expansion port 13;Work sacculus, which is provided with, in push rod 3 in work sacculus 1 fills mouth 9, the occlusion balloon
Occlusion balloon is provided with push rod 3 in 2 and fills mouth 10;Guidewire port 12 and the UNICOM of guidewire lumen 6;The first full two ends of chamber 7 point
Other UNICOM's work balloon dilatation port 14 and work sacculus fill mouth 9;The second full two ends of chamber 8 difference UNICOM occlusion balloon expands
Port 13 and occlusion balloon fill mouth 10.Seal wire, guidewire port 12 are installed by the passage of guidewire port 12, the formation of guidewire lumen 6
Just guidewire lumen 6 is set.The full chamber 7 in work balloon dilatation port 14, first and work sacculus fill mouth 9 and formed to work sacculus
1 passage filled, it is full for work sacculus 1.Second full chamber 8 and occlusion balloon fill mouth 10 and formed to occlusion balloon
2 passages filled, it is full for occlusion balloon 2.
Corresponding push rod 3, which is provided with, in the range of the work sacculus 1, the effective length of occlusion balloon 2 is used for sacculus positioning
Development positioner 11.Effective length scope refers to the length range of work sacculus 1 or the correspondence active section of occlusion balloon 2.Development
Positioner 11 can use developing ring, and its position can be shown under instrument detection.Positioner 11 develop respectively in work
Push rod 3 in sacculus 1 is set sets one or two to develop in the push rod 3 in one or more developing rings, occlusion balloon 2
Ring.
Embodiment 2, the basic structure be the same as Example 1 of the present embodiment, different structure is exactly that the push rod 3 is split group
Assembling structure;
As shown in figure 8, the push rod 3 includes two-chamber outer tube and inner tube, said inner tube is sleeved on one of two-chamber outer tube
In tube chamber, the tube chamber of said inner tube is guidewire lumen 6, and two tube chambers of two-chamber outer tube are respectively that the first full chamber 7 and second is filled
Chamber 8;
As shown in figure 9, the push rod 3 includes an outer tube and two inner tubes, two inner tubes are sleeved in outer tube side by side,
In two inner tubes, an inner tube tube chamber is guidewire lumen 6, and the cavity between another inner tube tube chamber and outer tube and inner tube is respectively
First full chamber 7 and second fills chamber 8;
In addition to said structure, push rod is that three bodys are set with composition successively, and central lumen is between guidewire lumen, three pipes
Cavity be respectively the first full chamber and the second full chamber.
Remaining structure be the same as Example 1, will not be repeated here.
Contrast test:By the foley's tube of the prior art contrast test related to the foley's tube progress of the present invention such as
Under:
1st, venting duration contrast is rushed
Any sacculus in commercially available traditional " sacculus of Bard 0.035 and embodiment 1 is done to the contrast for filling venting duration, for side
The double sacculus of face reflection fill venting duration and traditional single saccule fill venting duration indifference.Evaluation method:Noted in full device
Water, nominal pressure is filled by sacculus, and record is filled and the pressure release used time.
2nd, residue carrying drug ratio after simulation conveying is washed away
By any sacculus in commercially available traditional " sacculus of Bard 0.035 and embodiment 1,2 using same size, same recipe,
Medicinal balloon is made in same process, identical drugloading rate, and sacculus is delivered to target area half by in-vitro simulated use through same time
Full work sacculus, as shown in Figure 1,3, continuation simulation blood washes away sacculus to the set time, during this period by embodiment
The small sacculus of sacculus fill to blocking and simulate blood flow state, reach after fixed flushing time and work sacculus cut into HPLC tests
Remaining drugloading rate, calculates remaining carrying drug ratio.
3rd, simulation uses rear medicine reprinting rate
Commercially available traditional " sacculus of Bard 0.035 and any sacculus in embodiment are used into same size, same recipe, identical
Medicinal balloon is made in technique, identical drugloading rate, and extracorporeal blood vessel is removed and extracts blood with 50% methanol aqueous solution by in-vitro simulated use
Medicine in pipe, room temperature ultrasound 30min simultaneously centrifuges 10min, HPLC test doses, calculates reprinting rate.Correction data such as following table institute
Show:
Remarks:Data in table are means standard deviation
As shown in Table 1:
(1) this pair of sacculus and the " conventional balloons of tradition the Bard 0.035 almost indifference on venting duration is filled, illustrate this hair
Bright sacculus can reach that identical rushes venting duration after the design by lumenal cross-section with conventional balloon so that in apparatus in behaviour
The operating time same with traditional instruments is reached during work, does not increase the operating time of doctor, apparatus is reduced in patient's body
The potential risk that Shi Keneng is brought.
(2) this sacculus after equal flushing time drugloading rate apparently higher than conventional balloon drugloading rate, illustrate that small sacculus exists
There is blocking blood flow in operation overshoot, effectively prevent the medicine of work sacculus by the souring of blood flow, on increase work sacculus
The carrying drug ratio of attachment.
(3) the reprinting rate after this sacculus simulation use simulates the reprinting rate after use apparently higher than conventional balloon, illustrates
Prevented under the effect of small sacculus work sacculus by blood wash away increased attachment dose can with reprinting arrive diseased region, increase medicine
Effective reprinting rate of thing.
Claims (10)
1. a kind of pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that including push rod;
The push rod distal end is respectively fixed with the work sacculus for adhering to medication coat and the obstruction ball for blocking blood flow
Capsule;
Be provided with the push rod guidewire lumen for being used to installing seal wire, first for being filled to work sacculus fill chamber and
The second full chamber for being filled to occlusion balloon, the first full chamber and work balloon lumen UNICOM, the second full chamber with
Occlusion balloon inner chamber UNICOM.
2. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the work sacculus is set
Put in the push rod of occlusion balloon near-end side, or the work sacculus is arranged on the push rod of occlusion balloon distal end side
On.
3. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the work sacculus
Diameter is slightly smaller than occlusion balloon diameter, or the work balloon diameter is identical with occlusion balloon diameter.
4. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the work sacculus
Active section is cylindrical, a diameter of 2-15mm, and the length of active section is 20-300mm.
5. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the occlusion balloon is
It is spherical, or the active section of the occlusion balloon is cylinder, a diameter of 2-20mm.
6. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the work sacculus with
Spacing between occlusion balloon is 0-90mm.
7. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the push rod near-end
Provided with catheter block, the catheter block is provided with guidewire port, work balloon dilatation port and occlusion balloon expansion port;
Obstruction ball is provided with the push rod being provided with push rod in work sacculus in the full mouth of work sacculus, the occlusion balloon
Capsule fills mouth;
Guidewire port and guidewire lumen UNICOM;
First full chamber two ends difference UNICOM work balloon dilatation port and work sacculus fill mouth;
Second full chamber two ends difference UNICOM's occlusion balloon expansion port and occlusion balloon fill mouth.
8. according to claim 1 pair of sacculus medicine-coated balloon dilating catheter, it is characterised in that the work sacculus,
Corresponding push rod, which is provided with, in the range of occlusion balloon effective length is used for the development positioner that sacculus is positioned.
9. double sacculus medicine-coated balloon dilating catheters according to claim 1-8 any one, it is characterised in that described
The multi-lumen tube that push rod is formed in one, push rod is filled along longitudinal direction provided with guidewire lumen spaced apart from each other, the first full chamber and second
It is full of chamber.
10. double sacculus medicine-coated balloon dilating catheters according to claim 1-8 any one, it is characterised in that institute
Push rod is stated for separable assembled structure;
The push rod includes two-chamber outer tube and inner tube, and said inner tube is sleeved in a tube chamber of two-chamber outer tube, said inner tube
Tube chamber be guidewire lumen, two tube chambers of two-chamber outer tube are respectively the first full chamber and the second full chamber;
Or the push rod includes an outer tube and two inner tubes, two inner tubes are sleeved in outer tube side by side, in two inner tubes,
One inner tube tube chamber is guidewire lumen, the cavity between another inner tube tube chamber and outer tube and inner tube be respectively the first full chamber and
Second full chamber;
Or the push rod is that three bodys are set with composition successively, central lumen is the cavity difference between guidewire lumen, three pipes
For the first full chamber and the second full chamber.
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CN109938893A (en) * | 2017-12-18 | 2019-06-28 | 上海微创医疗器械(集团)有限公司 | Sacculus dilating catheter and its medicinal balloon |
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WO2019024726A1 (en) * | 2017-08-02 | 2019-02-07 | 杭州唯强医疗科技有限公司 | Balloon catheter with drug coating |
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CN109938893A (en) * | 2017-12-18 | 2019-06-28 | 上海微创医疗器械(集团)有限公司 | Sacculus dilating catheter and its medicinal balloon |
CN109091745A (en) * | 2018-06-13 | 2018-12-28 | 东莞科威医疗器械有限公司 | The operation intubation of the double sacculus of band |
CN109091745B (en) * | 2018-06-13 | 2021-07-16 | 东莞科威医疗器械有限公司 | Operation cannula with double saccules |
CN109621162A (en) * | 2019-01-16 | 2019-04-16 | 上海心玮医疗科技有限公司 | A kind of medicinal balloon and its application method |
CN109621162B (en) * | 2019-01-16 | 2024-01-05 | 上海心玮医疗科技股份有限公司 | Medicine balloon and application method thereof |
CN110464405A (en) * | 2019-08-01 | 2019-11-19 | 江苏义倍医疗科技股份有限公司 | A kind of Multifunctional triangle balloon-stent easy to operate |
CN110522990A (en) * | 2019-10-11 | 2019-12-03 | 上海申淇医疗科技有限公司 | A kind of dual balloon catheter |
CN110522990B (en) * | 2019-10-11 | 2020-12-22 | 上海申淇医疗科技有限公司 | Double-balloon catheter |
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