CN114558840A - Method for cleaning artificial lens - Google Patents
Method for cleaning artificial lens Download PDFInfo
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- CN114558840A CN114558840A CN202011360188.2A CN202011360188A CN114558840A CN 114558840 A CN114558840 A CN 114558840A CN 202011360188 A CN202011360188 A CN 202011360188A CN 114558840 A CN114558840 A CN 114558840A
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- 238000004140 cleaning Methods 0.000 title claims abstract description 213
- 238000000034 method Methods 0.000 title claims abstract description 39
- 239000007788 liquid Substances 0.000 claims abstract description 6
- 238000002360 preparation method Methods 0.000 claims abstract description 5
- 238000004506 ultrasonic cleaning Methods 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 238000005406 washing Methods 0.000 claims description 8
- 238000007710 freezing Methods 0.000 claims description 5
- 230000008014 freezing Effects 0.000 claims description 5
- 239000012153 distilled water Substances 0.000 claims description 3
- 229910021642 ultra pure water Inorganic materials 0.000 claims description 3
- 239000012498 ultrapure water Substances 0.000 claims description 3
- 239000012535 impurity Substances 0.000 abstract description 14
- 230000003749 cleanliness Effects 0.000 abstract description 8
- 208000035965 Postoperative Complications Diseases 0.000 abstract description 4
- 239000012634 fragment Substances 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000003287 optical effect Effects 0.000 description 21
- 239000007779 soft material Substances 0.000 description 12
- 239000013078 crystal Substances 0.000 description 10
- 239000002245 particle Substances 0.000 description 8
- 230000008569 process Effects 0.000 description 6
- 238000005265 energy consumption Methods 0.000 description 5
- 230000007704 transition Effects 0.000 description 5
- 239000000463 material Substances 0.000 description 3
- 206010036346 Posterior capsule opacification Diseases 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
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- 239000012530 fluid Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
- B08B3/12—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/048—Overflow-type cleaning, e.g. tanks in which the liquid flows over the tank in which the articles are placed
Abstract
The invention provides a method for cleaning an artificial lens, which sets the cleaning medium at a specific temperature, so that the artificial lens is in a hardening state during cleaning, the artificial lens is less prone to deformation during cleaning, the surface viscosity of the artificial lens in the hardening state is reduced, the adhesion to impurity fragments is weakened, the cleaning is facilitated, and the cleanliness of the artificial lens after cleaning is improved, thereby avoiding postoperative complications such as inflammation and the like caused by the impurity fragments on the surface of the artificial lens which is not cleaned after being implanted into eyes. The method for cleaning the artificial lens comprises the following steps: a preparation step of providing a cleaning tank with an opening at the upper part to contain a liquid cleaning medium, and fixedly arranging the artificial lens 1 in the cleaning tank to be soaked in the cleaning medium; a cleaning step of applying ultrasonic vibration to the cleaning tank to clean the intraocular lens, wherein, in the cleaning step, the cleaning medium is maintained at a specific temperature so as to put the intraocular lens in a hardened state.
Description
Technical Field
The invention mainly relates to the field of artificial lenses, in particular to a method for cleaning artificial lenses.
Background
An intraocular lens is an artificial lens that can be implanted in the eye to replace the natural lens in a human eye that has become clouded due to cataract disease, or for refractive surgery to correct the vision of the human eye. The intraocular lens is made of a transparent polymer material. These polymeric materials may be hard or soft. Intraocular lenses made of hard materials must be inserted into the eye through a large incision (usually larger than 6 mm), and the larger the insertion incision, the more likely various complications are to occur after the operation, and thus they have been substantially eliminated in developed countries. Intraocular lenses made of soft materials, also often referred to as foldable intraocular lenses, can be implanted into the eye through a small incision (typically 2-3 mm) after folding or crimping. The smaller the implantation incision, the less postoperative complications.
The soft materials currently used to make foldable intraocular lenses are mainly polyacrylates. The processing method is to carry out low-temperature milling on the polyacrylate coarse blank, and a plurality of impurities such as fine raw material particles and the like generated in the milling process are inevitably attached to the surface of the finished artificial crystal. In the prior art, a method of removing fine impurities adhering to the surface of an intraocular lens by rubbing the intraocular lens fixed to a cleaning device with dust removing particles, dust removing powder, a surfactant and water at ambient temperature has been mainly used.
However, when the intraocular lens is fixed with the cleaning device, the middle optical part is in a suspended state, and the intraocular lens is easily dropped downward due to the impact of the cleaning medium during cleaning, thereby causing the deformation and even the damage of the intraocular lens. In addition, the surface of the soft material has certain viscosity at normal temperature, and the fine impurities adhered to the surface of the artificial lens are difficult to remove by simple washing and friction. Therefore, the surface cleanliness of the artificial lens is poor, the quality of the finished artificial lens is affected, and even the risk of postoperative complications is high.
Disclosure of Invention
The invention aims to provide a method for cleaning an artificial lens, which can solve the problems that the artificial lens is easy to drop and deform when cleaned after being processed and the surface cleanliness of the artificial lens after being cleaned is poor due to the fact that fine particles are easy to adsorb on the surface because the surface viscosity of a soft material is high and complications such as Posterior Capsule Opacification (PCO) are easy to cause when the artificial lens enters eyes in the prior art.
The invention provides a method for cleaning an artificial lens. The intraocular lens includes: the optical part is formed into a circular sheet-shaped light-transmitting structure made of soft material at normal temperature, and the supporting loop extends from the edge of the optical part to the direction far away from the optical part. The method for cleaning the artificial lens comprises the following steps:
step S1: a preparation step, providing a cleaning tank with an opening at the upper part for containing a liquid cleaning medium, and fixedly arranging the artificial lens in the cleaning tank to be soaked in the cleaning medium;
step S2: a cleaning step of applying ultrasonic vibration to the cleaning tank to clean the intraocular lens, wherein in the cleaning step S2, the cleaning medium is maintained at a specific temperature so that the intraocular lens is in a hardened state.
It should be noted that the cleaning medium is maintained at a temperature that causes the intraocular lens to harden, i.e., the soft material of the intraocular lens reaches below its phase transition temperature as the temperature of the medium decreases, which varies depending on the soft material used for the intraocular lens.
According to the technical scheme of the invention, the artificial crystal is immersed in the cleaning medium, the ultrasonic wave is applied to the cleaning medium for cleaning, the cleaning medium subjected to the ultrasonic vibration uniformly generates small impact in all directions, and the artificial crystal can be prevented from falling off and deforming from the clamp due to unidirectional cleaning impact by cleaning in the mode. In addition, the cleaning medium is set to be not more than the phase transition temperature of the intraocular lens so that the intraocular lens immersed therein is kept in a hardened state, whereby deformation is less likely to occur at the time of cleaning and the surface tackiness is reduced, and the adhesion to foreign matter debris becomes weak, which is more advantageous for cleaning. Therefore, the cleanness of the cleaned artificial lens can be effectively improved, and postoperative complications such as inflammation and the like caused by impurity chips on the surface of the artificial lens which is not cleaned after being implanted into eyes are avoided.
As a preferred embodiment of the present invention, the cleaning step S2 is performed by an overflow method.
According to the technical scheme, the artificial lens in the hardening state is cleaned in an overflow cleaning mode. The overflow cleaning means that the cleaning medium is overflowed from the cleaning tank by continuously introducing the cleaning medium into the cleaning tank. Thereby keeping the cleaning medium in the vicinity of the intraocular lens in a renewed state during cleaning. This is because, in a general ultrasonic cleaning process, since the range of action of ultrasonic vibration is small, the foreign substance fragments washed off from the intraocular lens do not immediately move away from the intraocular lens but easily remain concentrated in the cleaning medium in the vicinity thereof, so that there is a risk that the foreign substance having been washed off secondarily adheres to the intraocular lens. Therefore, by adopting an overflow mode in the cleaning process, impurities and debris attached to the surface of the artificial lens are subjected to ultrasonic cleaning and then overflow from the cleaning tank along with the cleaning medium and are finally discharged, so that the risk of secondary attachment is reduced.
As a better technical scheme of the invention, the cleaning method further comprises the following steps:
step S21, a first ultrasonic cleaning step of cleaning the intraocular lens at a first cleaning frequency;
step S22, a second ultrasonic cleaning step, cleaning the intraocular lens at a second cleaning frequency after the first ultrasonic cleaning step.
According to the technical scheme, the artificial crystal is purposefully cleaned step by adjusting the frequency of ultrasonic cleaning, specifically, large particles are cleaned at a lower frequency, and then small particles which are difficult to remove are cleaned at a relatively higher frequency, so that the cleaning reliability is further improved.
Among them, preferably, the first ultrasonic cleaning step S21 is performed for 10 to 15 minutes, and the second ultrasonic cleaning step S22 is performed for 10 to 15 minutes. By controlling the time length of the first ultrasonic cleaning step S21 and the second ultrasonic cleaning step S22, the relationship between the cleanliness and the energy consumption is balanced, thereby reducing the energy consumption while ensuring the cleanliness of the artificial crystal.
As a preferred embodiment of the present invention, the overflow cleaning method is that in the cleaning step S2, the flowing cleaning medium is continuously introduced from the upper opening of the cleaning tank to the bottom of the cleaning tank, so that the cleaning medium in the cleaning tank is continuously increased and finally overflows from the upper opening of the cleaning tank.
According to the technical scheme, the mode of introducing the cleaning medium to the bottom of the cleaning tank can be that the cleaning medium is introduced into the bottom of the cleaning tank by extending the cleaning medium into the bottom of the cleaning tank through a pipeline, or a liquid inlet capable of being controlled to be opened and closed is arranged at the lower part of the cleaning tank so as to introduce the cleaning medium, and the mode is not limited herein. Through letting in cleaning medium and making it spill over from cleaning tank upper portion opening to the cleaning tank bottom, can need not to control the relation between top water inlet speed and the below play water speed and can guarantee that the intraocular lens soaks in cleaning medium to can avoid the top to intake the water flower that probably leads to and bring the impurity pollution cleaning medium in the air into.
In the preferred embodiment of the present invention, in the cleaning step S2, the temperature of the cleaning medium is maintained in a range of less than 11.5 ℃ and higher than the freezing point of the cleaning medium.
According to this solution, the temperature of the cleaning medium is further limited, and it will be understood by those skilled in the art that in the cleaning medium below 11.5 ℃, the intraocular lens (especially the more common intraocular lens made of polybenzoate) is at a temperature below the phase transition temperature and thus in a hardened state, and the lowest temperature of the cleaning medium is not lower than the zero point of the cleaning medium, so as to avoid the damage to the intraocular lens caused by the change of the properties of the cleaning medium due to too low temperature.
As a preferred embodiment of the present invention, the intraocular lens is fixed at a height from the bottom 1/3 of the cleaning bath. Therefore, the artificial crystal can be kept in a suspended state in the cleaning tank away from the bottom of the cleaning tank, and the artificial crystal cannot be polluted or damaged by touching the bottom of the cleaning tank and is always submerged by a cleaning medium.
Among them, the cleaning medium is preferably selected from any one of ultrapure water, triple distilled water and ionized water. Any one of the above sterile waters is selected as the cleaning medium, which avoids the risk of introducing impurities from the medium. Further, since water has a large thermal capacity and a property of gently changing temperature as the cleaning medium, it is easy to control the temperature, and the freezing point is lower than the phase transition temperature at which the soft material is hardened, so that the liquid state can be maintained during cleaning.
Drawings
FIG. 1 is a schematic view of an intraocular lens structure to which a method for cleaning an intraocular lens according to the present invention is applied;
FIG. 2 is a schematic flow chart of a method for cleaning an intraocular lens provided in a first embodiment of the present invention;
FIG. 3 is a schematic structural view showing a state in which an intraocular lens is fixed to a holder in a cleaning method for an intraocular lens provided in a second embodiment of the present invention;
FIG. 4 is a schematic view showing the structure of the cleaning state in the cleaning tank in the method for cleaning an intraocular lens according to the second embodiment of the present invention
Description of the reference numerals
1, an intraocular lens;
1a, an optic;
1b, a support tab;
2, clamping;
2a, a hollow portion;
2b, a fixed part;
3, cleaning a tank;
4, cleaning medium.
Detailed Description
The present invention will be described in detail with reference to specific examples. The following examples will aid those skilled in the art in further understanding the present invention, but are not intended to limit the invention in any manner. It should be noted that it would be obvious to those skilled in the art that various changes and modifications can be made without departing from the spirit of the invention. All falling within the scope of the present invention.
Fig. 1 is a schematic structural diagram of an intraocular lens to which an intraocular lens cleaning method according to the present invention is applied, and as shown in fig. 1, an intraocular lens 1 to which an intraocular lens cleaning method according to the present invention is applied includes: an optical portion 1a formed as a light-transmitting structure of a circular sheet shape which is a soft material at normal temperature; and a support loop 1b extending from the edge of the optical portion 1a in a direction away from the optical portion 1 a.
Specifically, the optical part 1a needs to be fixed in the eye after being implanted into the eye to ensure the stability of imaging, so a support loop 1b far away from the optical part is arranged at the edge of the optical part, so that the intraocular lens can be better fixed with the tissues in the eye after being implanted into the eye, and in addition, the support loop 1b can be fixed with a clamp during cleaning so that the optical part 1a is suspended, thereby avoiding friction from influencing the precision of the optical part 1 a.
It should be noted that, although fig. 1 shows an example in which the support loop 1b is formed in a C-shaped linear structure and is disposed opposite to the edge of the optical portion 1a, the present invention is not limited to this, and other support loops 1b that can engage with the intraocular tissue and fix the optical portion 1a, such as an L-shaped linear support loop 1b or a C-shaped sheet-like support loop 1b, extending from the edge of the optical portion 1a in a direction away from the optical portion 1a may be applied to the present invention.
In addition, although the optical portion 1a is exemplarily shown as a circular sheet-like light-transmitting structure in which both surfaces orthogonal to the axial direction are flat in fig. 1, it will be understood by those skilled in the art that the optical portion 1a may be formed as an optical portion 1a in which both surfaces orthogonal to the axial direction are spherical or one surface is spherical and the other surface is flat, depending on the soft material, and the intraocular lens having these optical portions 1a is also applicable to the present invention.
The following will further describe an intraocular lens cleaning method according to the present invention with reference to specific embodiments based on the intraocular lens 1.
In an embodiment of the present invention, a method for cleaning an intraocular lens is provided. The method of cleaning an intraocular lens may be applied to the intraocular lens 1 shown in fig. 1, and further, the method of cleaning an intraocular lens 1 may be applied to any intraocular lens 1 formed by processing a soft material.
Fig. 2 is a schematic flow chart of a method for cleaning an intraocular lens provided in the present embodiment, which is as follows in the present embodiment, as shown in fig. 2:
first, a preparation step S1 is performed. In the preparation step S1, the cleaning tank 3 is set in the ultrasonic apparatus in advance, and the cleaning tank 3 is an open container with an open upper part, and is a generally rectangular metal tank, and the shape and material thereof may be arbitrarily changed as necessary.
Next, a cleaning medium 4 is injected into the cleaning tank. As an initial state, the cleaning medium 4 may be injected throughout the cleaning bath at a location of height 2/3 to ensure that the intraocular lens is always immersed in the cleaning medium. It is of course also possible to not inject the cleaning medium 4 beforehand, but to inject the cleaning medium 4 by activating the overflow after that.
At the same time, the temperature of the cleaning medium needs to be controlled so that it remains stable at a temperature below the phase transition temperature of the intraocular lens and above the freezing point of the cleaning medium. By stable is meant that the temperature of the cleaning medium remains relatively stable without exceeding the above temperature range. Specifically, taking the more common intraocular lens made of polybenzoate as an example, the temperature of the cleaning medium is maintained in the range of 0 ℃ to 11.5 ℃.
The cleaning medium can be any one of sterile water such as ultrapure water, triple distilled water, ionized water and the like. Sterile water is selected as a cleaning medium, so that other impurities can be avoided, and the water has large thermal capacity, so that the temperature can be smoothly changed and is easy to control. In addition, since the freezing point of water is lower than the critical temperature for hardening the soft material, the water can be kept in a liquid state during cleaning. Therefore, the artificial lens is soaked in the cleaning medium which is kept within the specific temperature range, so that the artificial lens is always in a hardening state in the cleaning process, the possibility that the artificial lens is damaged due to the fact that the nature of the cleaning medium is changed due to too low temperature is avoided, and the method for cleaning the artificial lens in the hardening state is realized.
Examples of the means for controlling the temperature of the cleaning medium include various fluid temperature control devices known in the art, such as a constant temperature water bath and a water chiller, and the temperature control devices are not limited as long as the intraocular lens can be immersed in the cleaning medium maintained in the above temperature range and the cleaning medium can be cleaned by overflowing.
It should be noted that in the present embodiment, the case where the cooling step of the cleaning medium 4 is performed prior to the intraocular lens 1 placement step is exemplified, but the present invention is not limited thereto, and the cooling step may be performed after the intraocular lens 1 is immersed in the cleaning medium 4. It would not be departing from the scope of the invention as long as it enables the intraocular lens to be cleaned in a state of remaining hardened.
Next, a method of fixing the intraocular lens 1 to the jig 2 will be described. As shown in fig. 3 and 4, the jig 2 is formed in a plate shape and has a substantially elongated structure having a hollow portion 2 a. A plurality of sets of positioning projections are provided at equal intervals on a pair of long sides of the hollow portion 2a, and a pair of support tabs 1b of the intraocular lens 1 can be fitted correspondingly therein to perform a fixing function. Thus, the optical portion 1a of the intraocular lens 1 fixed to the jig 2 is positioned just above the hollow portion 2a and suspended, and the cleaning medium 4 can flow in the vertical direction of the intraocular lens 1. Screw holes are formed at both ends of the jig 2 so that the jig 2 can be fixed to the washing tub 3 by bolts 2 b. Both end portions of the jig 2 are formed to protrude upward relative to the hollow portion 2a, and the plurality of jigs 2 are engaged with each other when stacked in layers, so that the plurality of jigs 2 are positioned in the lateral direction. Meanwhile, the plurality of clamps 2 are longitudinally positioned by one bolt member vertically penetrating the screw holes of the respective clamps 2, so that the plurality of clamps 2 are completely overlapped in the vertical direction without being displaced. In the case where a plurality of jigs 2 are fixed in a stacked manner, the convex portions at both ends are in contact with each other and stacked, and the hollow portions 2a of the two jigs 2 in contact with each other from above and below are also in close contact with each other with a small gap therebetween, so that the intraocular lens 1 can be prevented from floating on the cleaning medium 4 and falling off from the gap during the cleaning process.
As shown in fig. 4, the bolts for fixing the jig 2 are provided at the bottom of the cleaning tank 3, and the jig 2 can be set in the cleaning tank 3 by screwing the bolts into the screw holes at the end of the jig 2. For example, the jig 2 is fixed at a height from the bottom 1/3 of the cleaning tank 3, but may be at any height as long as the jig 2 is not in contact with the bottom of the cleaning tank 3 and is not higher than the opening position of the cleaning tank 3.
In addition, it is preferable that the width of the holder 2 is larger than the length of the intraocular lens 1 including the support loop 1 b. In other words, it is preferable that the intraocular lens 1 provided on the jig 2 does not protrude outside the jig 2, so that contact between the intraocular lens 1 and the cleaning tank 3 can be prevented and contact damage can be avoided in the process of setting the jig 2 to which the intraocular lens 1 is fixed on the cleaning tank 3.
After the jig 2 on which the intraocular lens 1 is placed is fixed to the cleaning tank 3, a cleaning step S2 is performed. Specifically, the overflow device on the cleaning tank 3 is started and the ultrasonic vibration device is started.
The overflow means is a means for continuously introducing the cleaning medium 4 into the cleaning tank 3 so as to finally overflow from the upper opening of the cleaning tank 3. The overflow means may be a flow path for supplying the cleaning medium 4 to the cleaning tank 3 from any position such as an upper portion or a lower portion, but is preferably provided from the lower portion.
And simultaneously starting ultrasonic vibration equipment to apply ultrasonic vibration to the cleaning tank 3. Specifically, the lower frequency ultrasonic cleaning step S21 is performed first for 10 to 15 minutes. The cleaning medium 4 vibrates along with the vibration, small impact is generated uniformly in all directions, so that the phenomenon that the artificial lens 1 falls off and deforms from the clamp 2 due to unidirectional cleaning impact is avoided, the impact in all directions acts on the surface of the artificial lens 1 in a hardening state, and large impurity particles on the surface of the artificial lens 1 are taken away. Next, a relatively high frequency ultrasonic cleaning step S2 is performed for 10 to 15 minutes after adjusting the vibration frequency to clean the fine impurity particles on the surface of the artificial crystal 1.
In the embodiment, the artificial crystal is cleaned step by adjusting the frequency of ultrasonic cleaning, which is to clean large particles at a lower frequency and then clean small particles which are difficult to remove at a higher frequency in a targeted manner. Therefore, the cleanliness is ensured, the energy consumption is saved, and the influence of vibration on the surface precision of the artificial crystal is reduced. In addition, the relationship between the cleanliness and the energy consumption can be balanced by controlling the time length of the first ultrasonic cleaning step S21 and the second ultrasonic cleaning step S22, and the cleanliness energy consumption control of the intraocular lens is further considered.
At this time, since the cleaning medium 4 is in a hardened state within a specific temperature range, deformation is not easily generated at the time of cleaning, and the surface tackiness of the intraocular lens in the hardened state is reduced. Thereby weakening the adhesion to foreign debris and facilitating cleaning. In such a case, the intraocular lens in a hardened state is subjected to ultrasonic vibration cleaning in an overflow manner. The foreign matter debris attached to the surface of the intraocular lens 2 is subjected to ultrasonic vibration to float in the cleaning medium 3 away from the intraocular lens surface and overflow the cleaning tank 3 together with the flowing intraocular lens 2.
By continuously introducing the cleaning medium 4 into the cleaning tank 3, the cleaning medium 4 is gradually filled in the whole cleaning tank 3 and finally overflows from the upper opening, so that the cleaning medium near the artificial lens is always in a flowing state in the cleaning process, and the impurity chips separated from the artificial lens 2 are not stopped near the artificial lens 2 and are discharged along with the flowing of the cleaning medium 3.
And through letting in cleaning medium 4 to the washing tank 3 bottom and overflowing from the washing tank upper portion opening again, for in the washing mode of going into from the top down, need not control the relation between top influent velocity and the below play water velocity just can guarantee that intraocular lens 1 soaks in cleaning medium to can avoid the top to intake the water splash that probably leads to and bring into the impurity pollution cleaning medium in the air.
In the above embodiments of the present specification, although the steps are denoted by the numbers S1 to S2, the numbers are merely for convenience of description, and do not limit the execution timing of the steps.
In the above embodiments, the descriptions of the embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments or descriptions about cleaning.
It should be noted that the above are only some specific embodiments of the present invention, and should not be construed as limiting the scope of the present invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. A method of cleaning an intraocular lens, comprising:
the preparation method comprises the following steps: providing a cleaning tank with an opening at the upper part for containing a liquid cleaning medium, and fixedly arranging the artificial lens in the cleaning tank to be soaked in the cleaning medium;
a cleaning step: applying ultrasonic vibration to the cleaning tank to clean the intraocular lens,
in the cleaning step, the cleaning medium is maintained at a specific temperature so as to put the intraocular lens in a hardened state.
2. The method of cleaning an intraocular lens of claim 1,
and cleaning in an overflow mode in the cleaning step.
3. The method of cleaning an intraocular lens of claim 2,
the cleaning step further comprises:
a first ultrasonic cleaning step of cleaning the intraocular lens at a first cleaning frequency;
a second ultrasonic cleaning step of cleaning the intraocular lens at a second cleaning frequency after the first ultrasonic cleaning step,
the first cleaning frequency is less than the second cleaning frequency.
4. The method of cleaning an intraocular lens of claim 3,
the first ultrasonic cleaning step is carried out for 10 to 15 minutes,
the second ultrasonic cleaning step is carried out for 10 to 15 minutes.
5. The method of cleaning an intraocular lens of claim 3,
the overflow manner is that, in the cleaning step, the flowing cleaning medium is continuously introduced from the upper opening of the cleaning tank to the bottom of the cleaning tank, so that the cleaning medium in the cleaning tank is continuously increased and finally overflows from the upper opening of the cleaning tank.
6. The method for cleaning an intraocular lens according to any one of claims 1 to 5,
in the washing step, the temperature of the washing medium is maintained in a range of less than 11.5 ℃ and above the freezing point of the washing medium.
7. The method for cleaning an intraocular lens according to any one of claims 1 to 5,
the intraocular lens is fixed at a height from the bottom 1/3 of the cleaning tank.
8. The method for cleaning an intraocular lens according to any one of claims 1 to 5,
the cleaning medium is any one selected from ultrapure water, triple distilled water and ionized water.
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| CN202011360188.2A CN114558840B (en) | 2020-11-27 | 2020-11-27 | Method for cleaning artificial lens |
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|---|---|---|---|
| CN202011360188.2A CN114558840B (en) | 2020-11-27 | 2020-11-27 | Method for cleaning artificial lens |
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| CN114558840A true CN114558840A (en) | 2022-05-31 |
| CN114558840B CN114558840B (en) | 2023-11-28 |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946470A (en) * | 1988-04-01 | 1990-08-07 | Ceskoslovenska Akademie Ved | Hard intraocular lens with the shape memory |
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| CN110548725A (en) * | 2019-10-21 | 2019-12-10 | 上海加奇生物科技苏州有限公司 | Ultrasonic cleaning device system for implant raw material and method for cleaning implant raw material |
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| US5176686A (en) * | 1987-03-26 | 1993-01-05 | Poley Brooks J | Apparatus for packaging, folding, rigidifying and inserting an intraocular lens |
| US4946470A (en) * | 1988-04-01 | 1990-08-07 | Ceskoslovenska Akademie Ved | Hard intraocular lens with the shape memory |
| EP1138282A1 (en) * | 2000-03-30 | 2001-10-04 | Charles D. Kelman, M.D. | Intraocular lens assembly |
| JP2002050807A (en) * | 2000-08-02 | 2002-02-15 | Seiko Epson Corp | Manufacturing method of piezoelectric device and washing device |
| CN102599992A (en) * | 2012-03-16 | 2012-07-25 | 无锡蕾明视康科技有限公司 | Artificial lens with iris diaphragm |
| WO2014133413A1 (en) * | 2013-02-27 | 2014-09-04 | Velts Iakov Yakovlevich | Method for the ultrasonic cleaning of materials during the production of artificial crystals |
| CN105747393A (en) * | 2016-04-15 | 2016-07-13 | 嘉善天路达工贸有限公司 | Production technology for resin buttons |
| CN110548725A (en) * | 2019-10-21 | 2019-12-10 | 上海加奇生物科技苏州有限公司 | Ultrasonic cleaning device system for implant raw material and method for cleaning implant raw material |
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| CN114558840B (en) | 2023-11-28 |
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