CN114534997A - Point membrane device for preparing detection card - Google Patents

Point membrane device for preparing detection card Download PDF

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Publication number
CN114534997A
CN114534997A CN202210174936.0A CN202210174936A CN114534997A CN 114534997 A CN114534997 A CN 114534997A CN 202210174936 A CN202210174936 A CN 202210174936A CN 114534997 A CN114534997 A CN 114534997A
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CN
China
Prior art keywords
plate
conveying
groove
placing
moving
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Granted
Application number
CN202210174936.0A
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Chinese (zh)
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CN114534997B (en
Inventor
赵胜延
张盼盼
张磊
郑玉丽
魏静娟
王东
赵盼盼
杨长昆
李涛
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Henan Xianyan Biotech Co ltd
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Henan Xianyan Biotech Co ltd
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Priority to CN202210174936.0A priority Critical patent/CN114534997B/en
Publication of CN114534997A publication Critical patent/CN114534997A/en
Application granted granted Critical
Publication of CN114534997B publication Critical patent/CN114534997B/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/02Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
    • B05C5/0208Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C11/00Component parts, details or accessories not specifically provided for in groups B05C1/00 - B05C9/00
    • B05C11/10Storage, supply or control of liquid or other fluent material; Recovery of excess liquid or other fluent material
    • B05C11/1042Storage, supply or control of liquid or other fluent material; Recovery of excess liquid or other fluent material provided with means for heating or cooling the liquid or other fluent material in the supplying means upstream of the applying apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C13/00Means for manipulating or holding work, e.g. for separate articles
    • B05C13/02Means for manipulating or holding work, e.g. for separate articles for particular articles

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Abstract

The invention belongs to the technical field of preparation of laboratory detection cards, and particularly relates to a film dispensing device for preparation of a detection card. The film dispensing device for preparing the detection card comprises a shell, wherein the shell comprises a base and a top cover, a moving frame is arranged on the base and comprises a moving plate, point film plate placing grooves are sequentially and uniformly arranged along the length direction of the moving plate at intervals, a conveying through groove is arranged on the moving plate between every two adjacent point film plate placing grooves, and the positions of the conveying through grooves in the length direction of the moving plate correspond to each other and form a conveying channel; the moving frame further comprises a conveying mechanism, a driving mechanism and a vertical moving mechanism, wherein the conveying mechanism comprises a conveying belt, the conveying belt is arranged in the conveying channel, and a conveying groove is formed in the conveying belt; the top cover is provided with a point membrane plate placing opening, and the top cover is also provided with an injection device for dripping reagent on the point membrane plate in the placing groove. The film dispensing device for preparing the detection card is suitable for small-scale production of test strips in a laboratory and has high precision.

Description

Point membrane device for preparing detection card
Technical Field
The invention belongs to the technical field of preparation of laboratory detection cards, and particularly relates to a film dispensing device for preparation of a detection card.
Background
The immune colloidal gold technology is characterized in that an antigen or an antibody is marked by using colloidal gold, a corresponding paired antigen or antibody is coated on an NC membrane of a reagent, when a sample contains a corresponding specific antibody or antigen during detection, colloidal gold marked particles and a ligand in the sample are combined to form a compound, then chromatography is carried out on the NC membrane, the compound is spread by the coated antigen or antibody to form a detection T line visible to naked eyes, and the judgment of a result is realized through the existence of a detection line.
The test paper in the colloidal gold method diagnosis kit comprises a backing plate, an NC cellulose membrane arranged on the backing plate, a water absorption pad and the like, and the test paper (or the dot membrane plate) needs to be subjected to dot membrane and gold spraying treatment when being prepared. In the prior art, a point membrane machine for point membrane is generally operated in a winding mode by large-scale equipment, for example, the invention patent with the publication number of CN104096658A discloses a point membrane rolling machine which comprises a platform; the clamping groove device is arranged on the platform; the adjustable point membrane device is arranged on the platform and is positioned on one side of the clamping groove device; the film positioning device is arranged at the inlet of the clamping groove device and is positioned below one side of the platform; the constant-speed film rolling device is arranged at the outlet of the clamping groove device and is positioned below the other side of the platform. Such a large-scale apparatus is suitable for a factory for mass production, but in the development of a kit, when a small-scale test production is performed in a laboratory, it is generally not necessary to produce a large amount of kits, but a certain amount of kits or test strips must be produced for a wide range of tests, and the above apparatus is not suitable.
Disclosure of Invention
The invention aims to provide a point membrane device for preparing a detection card, which is suitable for small-scale production.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
a point membrane device for preparing a detection card comprises a shell, wherein the shell comprises a base and a top cover, a moving frame is arranged on the base and comprises a moving plate, a plurality of groups of placing grooves are formed in the moving plate, each group of placing grooves comprises point membrane placing grooves which are sequentially and uniformly arranged along the length direction of the moving plate at intervals, a conveying through groove is formed in the position, located between every two adjacent point membrane placing grooves, of the moving plate, the conveying through groove is a through groove and communicated with the two adjacent placing grooves, and the conveying through grooves corresponding to the placing grooves of each group correspond to each other in the length direction of the moving plate and form a conveying channel; the moving frame further comprises a conveying mechanism, a driving mechanism and a vertical moving mechanism, the conveying mechanism comprises a conveying belt, the whole or part of the conveying belt is arranged in a conveying channel and driven by the driving mechanism to move along the length direction of the moving plate, conveying grooves for placing the point membrane plates are sequentially arranged on the conveying belt at intervals along the length direction of the conveying belt, and the vertical moving mechanism can drive the conveying belt to move in the direction perpendicular to the moving plate when the conveying grooves correspond to the positions of the placing grooves so as to place the point membrane plates in the placing grooves or take the point membrane plates out of the placing grooves; the top cover is provided with a point membrane plate placing opening for placing the point membrane plate on the conveying belt through the point membrane plate placing opening, and the top cover is also provided with an injection device for dripping reagent on the point membrane plate in the placing groove.
And step surfaces of the placing grooves for supporting the point membrane plates placed in the point membrane plate placing grooves are arranged on the groove walls of the two ends of the point membrane plate placing grooves in the width direction of the moving plate.
The distance between the bottom of the through conveying groove and the step surface of the placing groove is larger than the thickness of the conveying belt.
Two groove side walls of the placing groove in the length direction of the moving plate are gradually inclined and close to each other in the direction from top to bottom.
The tank bottom of the point diaphragm plate standing groove is provided with a through hole.
The conveyer belt is endless conveyor, transport mechanism transfer gear and conveying axle, the transfer gear including be used for with conveyer belt complex initiative transfer gear and driven transfer gear, the conveying axle including respectively with the fixed initiative transfer gear and the driven transfer gear that set up of initiative transfer gear and driven transfer gear, the horizontal rotation of initiative transfer gear and driven transfer gear sets up the position that lies in the movable plate both ends on removing the frame, the part that lies in the conveying axle top of conveyer belt is in the movable plate top and follows pass through in the conveying passageway, the part that lies in the conveying axle below of conveyer belt is in the movable plate below.
The film dotting device also comprises a blanking device, the blanking device comprises a first guide plate and a second guide plate, the first guide plate comprises a first guide part matched with the shape of a transmission belt partially sleeved outside the driving transmission wheel or the driven transmission wheel, and a second guide part connected to the lower end of the first arc-shaped part and extending downwards; the second guide plate is matched with the second guide part of the first guide plate in shape and is arranged at intervals, and a sliding channel is formed by a gap between the second guide plate and the second guide part; an end portion of an upper end of the second guide plate is located higher in a vertical direction than a portion of the transmission belt located below the transmission shaft.
The second guide part and the second guide plate are arc-shaped plates, and the included angle between the tangent line of the arc surface of each arc plate and the horizontal direction is gradually increased from the top to the bottom.
The plate collecting device is arranged below the conveying belt and comprises a plate collecting box, a plate collecting groove which corresponds to the position of the sliding channel and is used for collecting the point film plates sliding downwards in the sliding channel is formed in the plate collecting box, the plate collecting box is in guide sliding fit with the moving frame or the base in the length direction of the conveying belt, and a plate collecting driving mechanism used for driving the plate collecting box to slide along the length direction of the conveying belt is connected to the plate collecting box.
The cover is provided with an air supply device used for supplying hot air into the shell, the air supply device comprises an air supply groove arranged in the top cover and a hot air nozzle arranged on the inner surface of the top cover and communicated with the air supply groove, and the injection device comprises a conveying groove arranged in the top cover and an injection pipe arranged on the inner surface of the top cover.
The invention has the beneficial effects that:
the film dispensing device for preparing the detection card is suitable for small-scale production of test strips in a laboratory, and during production, a film dispensing plate (comprising a backing plate box and an NC film) is only required to be placed on a conveying groove of a conveying belt, the conveying belt is moved to a proper position, the conveying belt moves downwards to enable the film dispensing plate to be placed in a placing groove, an injection device dispenses films to the film dispensing plate at a fixed position, the film dispensing plate stands still, and then the conveying belt takes away and collects the film dispensing plate.
Drawings
FIG. 1 is a schematic structural view of a spotting device for preparing a detection card;
FIG. 2 is a schematic structural view of a moving frame of a dispensing device for preparing a test card;
FIG. 3 is a schematic diagram showing the structure of a conveyor belt of the spot film device for preparing the test card;
FIG. 4 is a schematic structural view of a guide plate of the spotting device for preparing the detection card;
fig. 5 is a side view of a guide plate of the spot film device for preparing a test card.
Detailed Description
As shown in figures 1-5, the film dotting device for preparing the detection card is a small film dotting machine for a laboratory, and comprises a rack, wherein a film dotting mechanism is fixedly arranged on the rack, the film dotting mechanism comprises a supporting seat, and a film dotting table is arranged on the supporting seat. The film dispensing table comprises a base and a top cover, wherein the base comprises a bottom plate and four side plates arranged around the bottom plate. The bottom plate is the elongated structure, and the curb plate top that top cap and bottom plate are around can dismantle and be connected, and preferred here, top cap and the curb plate top lock around the bottom plate. After the top cover is connected with the bottom plate, an accommodating cavity is enclosed. The accommodating cavity is internally provided with a moving frame 1, the moving frame comprises an underframe and a moving plate 2 arranged on the underframe, and the moving plate is horizontally arranged.
The movable plate is provided with two groups of placing grooves, each group comprises a plurality of placing grooves 21, namely spot membrane plate placing grooves, and the two groups of placing grooves are distributed at intervals in the width direction (namely the front-back direction) of the movable plate. And the plurality of placing grooves of each group are sequentially arranged at intervals along the length direction of the moving plate. The standing groove is a rectangular long groove, and the length direction of the standing groove extends along the width direction (namely, the horizontal front-back direction) of the moving plate, so that more standing grooves can be arranged on the moving plate. The surface of two cell walls of standing groove along its width direction (direction about the level promptly) is the slope plane, and every cell wall is drawn close to in the direction of another cell wall gradually on the direction from last down for two cell walls have formed big-end-up's structure, when the diaphragm is placed to preventing and treating the groove, can receive blockking of cell wall and glide.
The through holes are formed in the groove bottom of each placing groove, so that the upper end and the lower end of each placing groove are opened, surrounding air can be in full contact with the membrane plate placed on the placing grooves, and the membrane plate is guaranteed to be uniform and stable. The width of the through hole at the bottom of the placing groove in the left-right direction is equal to the width of the placing groove, and the length of the through hole in the front-back direction is smaller than that of the placing groove in the same direction, so that steps are formed at the front end and the rear end of the placing groove, and the two ends of the membrane plate are placed on the horizontal step surfaces 22 of the steps. The distance value of the distance between the two groove walls of each placing groove in the left-right direction at the position with the same height as the horizontal step surface is equal to the width of the membrane plate, so that the membrane plate can accurately slide to a fixed position under the action of the groove walls when being placed in the placing groove, and the precise positioning of the membrane plate is realized.
In each group of the placing grooves, a conveying through groove is formed in the position, between two adjacent placing grooves, of the moving plate, and openings are formed in the left side and the right side of each conveying through groove except for an upper opening, so that the two adjacent placing grooves are communicated through the conveying through grooves. The front groove walls of all the conveying through grooves corresponding to each group of placing grooves are located on the same vertical plane extending along the left-right direction, and the rear groove walls of all the conveying through grooves are located on the same plane extending along the left-right direction. All the transfer through slots of each set of placement slots form one large channel. And the height position of the groove bottom of each group of the placing grooves in the vertical direction is lower than the positions of the horizontal step surfaces at the two ends of the placing grooves.
The moving frame is also provided with a conveying device. The conveying device comprises two endless conveyor belts 3 and two conveying shafts 31, each of which is provided with two conveying wheels 32. The two transmission shafts are a driving transmission shaft and a driven transmission shaft. The driving transmission shaft is connected with a driving motor, and the driven transmission shaft is rotatably connected to one end of the movable frame. Two conveying wheels on each conveying shaft are arranged at intervals along the axial direction of the conveying shaft, and the conveying belts are sleeved on the two corresponding conveying wheels on the two conveying shafts.
The conveying belt is provided with conveying grooves 33 at regular intervals along the length direction in sequence, the length direction of the conveying grooves extends along the front and back direction, and openings are formed in the front end and the back end of each conveying groove, so that the middle of the membrane plate can be placed in the conveying grooves and conveyed. The distance between the central lines of the two adjacent conveying grooves in the left-right direction is consistent with the distance between the central lines of the two adjacent placing grooves on the moving plate in the left-right direction, so that the membrane plates in the conveying grooves can be in one-to-one correspondence with the placing grooves. The width of the conveying groove is very close to that of the membrane plate, in other embodiments, the conveying groove can be arranged in a manner that the groove walls in the left and right directions are inclined, and only the conveying groove and the placing groove can be in one-to-one correspondence.
The thickness of conveyer belt is less, and still is little than the difference in height between the horizontal step face at the tank bottom of conveying through groove and standing groove both ends.
The driving transmission shaft and the driven transmission shaft are both arranged on the vertical moving plate, a sliding protrusion is arranged on the vertical moving plate, a sliding groove is arranged on the outer side of the vertical plate of the moving frame and matched with the sliding protrusion, and the vertical moving plate is controlled to move up and down through a gear and a rack. Make the conveyer belt when taking out the diaphragm plate from putting a board section of thick bamboo, be located higher position, the conveyer belt of being convenient for passes through smoothly from the movable plate top, and when all diaphragm plates all moved the standing groove that corresponds, vertical movable plate downwardly moving made the diaphragm plate place on the step at standing groove both ends to there is the space between messenger's diaphragm plate and the conveyer belt.
The chassis comprises two vertically arranged vertical plates, the upper ends of the two vertical plates are fixedly connected with the two ends of the movable plate respectively, and the lower ends of the two vertical plates are provided with sliding grooves respectively. The bottom plate of the base is provided with a sliding rail extending along the front-back direction, and the sliding groove is in sliding fit with the sliding rail, so that the moving frame can move in the front-back direction.
The vertical plate is provided with two large conveying holes, the conveying belt is annular and is tensioned by two conveying shafts and the conveying wheels, so that the conveying belt forms two horizontal belts which are respectively arranged up and down and circular-arc belts at two ends. One of the horizontal belts passes through the conveying through groove on the moving plate, and the other horizontal belt is arranged below the moving plate and passes through the conveying holes of the two vertical plates. Two conveying shafts are arranged on the outer side of the vertical plate.
Two feeding devices are arranged on the inner wall of one side plate of the substrate of the film dotting platform, each feeding device comprises a plate placing cylinder fixed on the inner wall of the corresponding side plate, and the plate placing cylinder is arranged above the moving plate. The plate placing cylinder is a square cylinder, one side wall of the square cylinder is fixedly connected with the inner wall of the corresponding side plate of the substrate, and the upper end and the lower end of the plate placing cylinder are open. Put the vertical setting of a board section of thick bamboo, and highly enough high in vertical direction makes and to place more diaphragm plates in putting a board section of thick bamboo. The upper end of the placing cylinder penetrates out of the top cover, a cover is arranged on an opening at the upper end, and the cover is covered after the membrane plate is placed in the plate placing cylinder.
The base is internally provided with a controller which is connected with a switch of the driving motor. The lower end of the plate placing cylinder is provided with a valve plate, a switch of the valve plate is connected with the controller and used for closing the lower end of the plate placing cylinder when the driving belt moves downwards under the driving of the vertical moving plate.
The lower end opening of the plate placing cylinder is attached to the corresponding conveying belt. The depth of the conveying groove on the conveying belt is set to be equal to the thickness of the membrane plate, so that only one membrane plate can be placed in the conveying groove on the conveying belt. Along with the motion of conveyer belt, the diaphragm plate is placed in next conveying recess, analogizes in proper order, makes gradually all place a diaphragm plate in each conveying recess of conveyer belt.
And a blanking device is arranged on a bottom plate of the substrate of the film dispensing table and comprises two groups of guide plates, and each group of guide plates comprises a first guide plate and two second guide plates 5. First deflector includes first arc portion 4, and the cross-section of the internal surface of first arc portion at its axis direction of perpendicular to (fore-and-aft direction) is the semicircle, and the appearance of first arc portion appearance and the circular arc area of conveyer belt is unanimous to the package is established in the outside in circular arc area, and the internal surface of first arc portion laminates with the surface in conveyer belt circular arc area almost, receives gravity and falls down when avoiding the lamina membranacea to convey on the circular arc area.
The lower extreme of the first arc portion of first deflector is connected with second arc portion 6, and the surface of second arc portion is the arc of quarter in the cross-section of perpendicular to fore-and-aft direction. The upper end of second arc portion and the lower extreme smooth connection of first arc portion, the tangent line vertical setting of lower extreme. The second guide plate is similar to the second arc-shaped part of the first guide plate in shape, the section of the second guide plate perpendicular to the front-back direction is also in the shape of a quarter arc, and the second guide plate and the second arc-shaped part are coaxially arranged. The spacing between the first guide plate and the second guide plate is approximately equal to the thickness of the membrane plate, but slightly greater than the thickness of the membrane plate.
The second deflector has two, sets up respectively in the both sides of the conveyer belt that corresponds, and the second deflector is close to the distance between the side of conveyer belt and the side of conveyer belt less, is less than the length that the diaphragm exposes the tip of conveyer belt far away. And the tip of the upper end of second deflector highly is higher than the tank bottom of the conveying recess on the lower horizontal band of conveyer belt on the vertical direction for the diaphragm plate on the lower horizontal band can slide along the second deflector when contacting the second deflector, and then when sliding to the second deflector lower extreme, the direction of diaphragm plate changes vertical setting into.
The position that is close to the lower extreme of two vertical boards that remove the frame is provided with the collecting board, and the collecting board level sets up, and both ends are close to the position fixed connection of lower extreme with two vertical boards respectively. Two plate collecting boxes are arranged on the collecting plate, each plate collecting box is of a long strip-shaped structure, a long groove is arranged in each plate collecting box, the width of each long groove is approximately equal to the length of the membrane plate, and the width of each long groove is slightly larger than the length of the membrane plate. Two sets of slide rails are arranged on the collecting plate and extend along the left and right directions. The length of the plate collecting box also extends along the left and right sides, and the lower surface of the bottom plate of the plate collecting box is provided with a sliding chute in sliding fit with the sliding rail. Two receipts plate box parallel interval sets up, and is provided with the connecting block on two relative lateral walls of two receipts plate box, is provided with the screw thread through-hole on the connecting block, and the axis of screw thread through-hole extends about following.
The lower extreme of two vertical boards of removal frame is provided with receives the board lead screw, and the both ends of receiving the board lead screw are rotated with two vertical boards through the bearing respectively and are connected, and the one end that receives the board lead screw and be close to loading attachment is provided with receives board step motor, and the control is received the board lead screw and is rotated and drive the connecting block and remove, and then drives and receive the board box and remove.
The length of receiving the board box slightly is less than the distance between two vertical boards, but the initial position setting of receiving the board box is in the one end that loading attachment was kept away from to the collecting plate, and the other end orientation of receiving the board box this moment is kept away from the direction extension of loading attachment. In the using process, the plate collecting screw rod is controlled to move step by step through the plate collecting stepping motor, and the membrane plate on the conveying belt is taken down from the conveying belt under the action of the first guide plate and the second guide plate and vertically falls into the plate collecting box. And setting the frequency of the plate collecting stepping motor to control the plate collecting screw rod to move for a distance of about one film plate thickness every time one film plate falls into the plate collecting box.
The inner box is sleeved with an inner box, the size of the inner box is basically consistent with that of the inner wall of the plate collecting box, and the inner box can be taken out of the plate collecting box to take out the membrane plate in the plate collecting box. One end of the lining box, which is close to the feeding device, is provided with an inclined block, and one end of the inclined block, which is far away from the feeding device, is provided with an inclined surface which inclines along a direction far away from the feeding device (namely towards the left) from top to bottom. When the film plate is lined with the box, the film plate is slightly inclined, so that the film plate is prevented from falling leftwards.
Be provided with injection apparatus on the top cap, injection apparatus is including dismantling the syringe pump that sets up at the top cap upper surface, and the entry of syringe pump passes through the pipe connection and treats the container of injection reagent, and the exit linkage of syringe pump has the conveyer pipe. The conveying pipe comprises a main conveying pipe and a branch conveying pipe.
The top cover is provided with a conveying groove, the conveying groove comprises a main conveying groove and a branch conveying groove, the length direction of the main conveying groove extends along the length direction of the top cover, namely extends along the left and right direction, and the main conveying groove is located at the position behind the width direction of the top cover. The length direction of the conveying branch groove extends along the width direction of the top cover, namely, along the front-back direction. The number and the position of the conveying branch grooves correspond to the placing grooves in the moving plate, and the rear end of each conveying branch groove is communicated with the conveying main groove.
The main conveying groove and the branch conveying groove are formed in the upper surface of the top cover, the main conveying pipe is arranged in the main conveying groove, and the branch conveying pipes are arranged in the branch conveying groove. Cover plates are arranged on the main conveying groove and the branch conveying groove, and the shape of each cover plate is matched with that of the main conveying groove and the branch conveying groove. After the cover plate is covered on the conveying groove, a space for accommodating the conveying pipe is formed in the conveying groove. The conveying branch pipe is provided with a plurality of conveying branch pipes, and the rear end of each conveying branch pipe is connected with the conveying main pipe.
And a conveying through hole is formed in the bottom wall of the front end groove of each conveying branch groove, and an injection pipe is arranged in each conveying through hole. The injection tube comprises a vertical section and a horizontal section, wherein the vertical section is large in top and small in bottom, the upper end of the vertical section penetrates through the conveying through hole and is fixedly connected with the top cover, the lower end of the vertical section extends downwards to a position close to the placing groove, one end of the horizontal section is connected with the upper end of the vertical section, and the other end of the horizontal section is connected with the front end of the conveying branch tube.
The top cover is provided with an air supply groove, and the air supply groove comprises an air supply main groove and an air supply branch groove. The air supply main groove is positioned at the position of the top cover close to the front end and extends along the left-right direction, and the air supply branch groove extends along the front-back direction. The positions of the air supply branch grooves correspond to the positions of the placing grooves on the moving plate one by one. The inner surface of the top cover is provided with a plurality of groups of air supply holes, and each group of air supply holes comprises a plurality of air supply holes which are sequentially and uniformly arranged at intervals along the front-back direction. Each group of air supply holes correspond to one air supply branch groove in position and are communicated with the air supply branch grooves. Specifically, the upper end opening of the air supply hole is arranged on the groove bottom wall of the air supply branch groove, and the lower end opening is arranged on the inner surface (on the lower surface) of the top cover.
An air supply groove cover is arranged on the air supply groove, the shape of the air supply groove cover is matched with that of the air supply groove, and the air supply groove cover is in sealing fit with the opening of the air supply groove on the top cover.
The outside of the posterior lateral plate of setting on the bottom plate is provided with air supply mechanism, and air supply mechanism includes the air pump that links to each other with the air supply, is connected with the heating pipe on the gas outlet of air pump, and the one end that the air pump was kept away from to the heating pipe links to each other with the notch of air supply owner groove to send into hot-blastly in the air supply owner groove. The heating pipe sets up to snakelike, and is concrete, and the heating pipe includes along many straight tubes that upper and lower direction parallel interval set up, is connected with the arc return bend between the corresponding tip of two adjacent straight tubes. The end of the straight pipe at the lowest side, which is not connected with the bent pipe, is connected with the air outlet of the air pump, and the end of the straight pipe at the highest side, which is not connected with the bent pipe, is connected with the notch of the air supply main groove. The heating pipe is fixed on the outer surface of the side plate through the fixing column, and an electric heating wire is wound outside the heating pipe and used for heating gas in the heating pipe.
The conveying branch groove is arranged between two adjacent air supply branch grooves, the lower end of the injection pipe is arranged between two adjacent air supply holes and just positioned between two corresponding air supply holes in the two adjacent air supply holes, so that hot air coming out of the air supply holes can heat liquid reserved in the injection pipe in time, and the temperature of the liquid dripped from the lower end of the injection pipe is not lower than a set temperature value.
A movable support frame is further arranged on a bottom plate of a base of the film dispensing table, an air cylinder is arranged on the movable support frame, and a piston of the air cylinder is connected with a movable lead screw. The lower surface of the collecting plate is also provided with a moving cylinder, the inner wall of the moving cylinder is provided with threads and is in threaded fit with the moving screw rod, so that the moving screw rod rotates to drive the moving frame to move upwards in the front-back direction. The membrane plate on the adjusting conveyor belt moves in the front-rear direction, so that different positions of the membrane plate correspond to the positions of the lower end ports of injection tubes, used for injecting reagents onto the membrane plate, on the top cover, and the requirements of different types of membrane plates are met. Furthermore, the length of the movable screw rod is set so that the two groups of placing grooves on the movable plate are positioned outside the base, and the plate collecting box filled with the film plates can be conveniently taken out from the rail.
When the film dotting device is used, the stacked film plates are added from the film preventing cylinder, and then the cover is covered. And opening a motor connected with a driving wheel of the conveying belt to enable the conveying belt to convey the membrane plate to a proper placing groove. Then the vertical moving plate drives the conveyor belt to move downwards, so that the membrane plate is placed on the steps at the two ends of the placing groove. The injection pipe of the conveying branch groove is provided with an electromagnetic valve, the electromagnetic valve is connected with the controller, and after the membrane plate is placed on the step, the injection pipe is controlled by the controller to dropwise add corresponding liquid onto the membrane plate. After the dripping, standing for a certain time, moving the conveyor belt upwards under the control of the controller to enable the membrane plate to fall into the conveying groove on the conveyor belt, then opening the conveyor belt, moving the membrane plate downwards, and enabling the membrane plate to be in a vertical state under the action of the guide plate and fall into the plate collecting box. And the plate collecting stepping motor is opened under the action of the controller, so that the plate collecting box moves rightwards, and the membrane plates gradually fall into the plate collecting box in sequence. After the board collecting box is full, the moving frame is conveyed outwards through the moving screw rod, then the lining box is taken out, meanwhile, another empty lining box is put in, and the moving frame is moved into the base again.
Further, the delivery branch grooves are not provided on the upper surface of the top cover, but are provided on the lower surface (inner surface) of the top cover. Specifically, one part of the groove body of the conveying branch groove of the top cover is positioned below the lower surface of the top cover, and the other part of the groove body is positioned above the lower surface of the top cover. The top cover is provided with a conveying branch groove, and the lower end of the conveying branch groove is provided with an opening on the lower surface of the top cover.
Be provided with the multiunit frid on the top cap lower surface, each transport branch groove corresponds a set of frid, and each group frid includes two perpendicular frids and a horizontal frid, and two perpendicular frids set up along the parallel interval of left right direction, set up respectively in the left and right sides in the transport branch groove that corresponds, erect frid length and extend along the fore-and-aft direction level, the lower fixed surface of the top side of perpendicular frid and top cap is connected. The left side and the right side of the transverse groove plate are respectively fixedly connected with the two corresponding vertical groove plates, so that a space enclosed by the two vertical groove plates and one transverse groove plate and the conveying branch groove part on the lower surface of the top cover jointly form a conveying branch groove, namely, a rectangular square cylinder is arranged on the lower surface of the top cover. Between two adjacent conveying branch grooves, two vertical groove plates corresponding to the two adjacent conveying branch grooves form a groove with a downward opening. The lower end opening of the air supply hole of the air supply branch groove is arranged at the groove bottom of the groove (namely the position of the corresponding lower surface of the top cover). The hot-blast that makes the supply-air outlet go out like this can directly be to the riser and the diaphragm effect of carrying the branch groove, heats the conveying liquid in the space that riser and diaphragm enclose, guarantees that the liquid in the transport branch groove flows to syringe department from the entrance of carrying the branch groove, just is heated to required temperature, and the temperature of the liquid that drips from the syringe is exactly required temperature.
Furthermore, the second arc-shaped part of the first guide plate and the lower end of the second guide plate are arranged to incline leftwards, so that the membrane plate is kept in a slightly inclined state after coming out and falls into the lining box, and the membrane plate is prevented from falling to the other side.

Claims (10)

1. A film dispensing device for preparing a detection card is characterized by comprising a shell, wherein the shell comprises a base and a top cover, a moving frame is arranged on the base and comprises a moving plate, a plurality of groups of placing grooves are formed in the moving plate, each group of placing grooves comprises film dispensing plate placing grooves which are sequentially and uniformly arranged along the length direction of the moving plate at intervals, a conveying through groove is formed in the position, located between two adjacent film dispensing plate placing grooves, of the moving plate, the conveying through groove is a through groove and communicated with the two adjacent placing grooves, and the conveying through grooves corresponding to the placing grooves of each group correspond to each other in the length direction of the moving plate and form a conveying channel; the moving frame further comprises a conveying mechanism, a driving mechanism and a vertical moving mechanism, the conveying mechanism comprises a conveying belt, the whole or part of the conveying belt is arranged in a conveying channel and driven by the driving mechanism to move along the length direction of the moving plate, conveying grooves for placing the point membrane plates are sequentially arranged on the conveying belt at intervals along the length direction of the conveying belt, and the vertical moving mechanism can drive the conveying belt to move in the direction perpendicular to the moving plate when the conveying grooves correspond to the positions of the placing grooves so as to place the point membrane plates in the placing grooves or take the point membrane plates out of the placing grooves; the top cover is provided with a point membrane plate placing opening for placing the point membrane plate on the conveying belt through the point membrane plate placing opening, and the top cover is also provided with an injection device for dripping reagent on the point membrane plate in the placing groove.
2. The spotting device for preparing a detection card according to claim 1, wherein a placing groove step surface for supporting the spotting plates placed in the spotting plate placing groove is provided on groove walls of both ends of the spotting plate placing groove in the moving plate width direction.
3. The spotting device for preparing a test card according to claim 2 characterized in that the distance between the bottom of the transfer groove and the step surface of the placing groove is larger than the thickness of the transfer belt.
4. The spotting device for preparing a detection card according to claim 3 wherein both slot side walls of the placement slot in the moving plate length direction are gradually inclined closer in the top-down direction.
5. The spotting device for preparing detection cards according to claim 4 characterized in that the groove bottom of the spotting plate placing groove is provided with a through hole.
6. The spotting device for preparing a detection card according to claim 1 characterized in that the conveyor is an endless conveyor, the transfer mechanism comprises a transfer wheel and a transfer shaft, the transfer wheel comprises a driving transfer wheel and a driven transfer wheel for cooperating with the conveyor, the transfer shaft comprises a driving transfer shaft and a driven transfer shaft fixedly arranged with the driving transfer wheel and the driven transfer wheel respectively, the driving transfer shaft and the driven transfer shaft are horizontally and rotatably arranged on the moving frame at positions at both ends of the moving plate, a portion of the conveyor above the transfer shaft is above the moving plate and passes through the transfer passage, and a portion of the conveyor below the transfer shaft is below the moving plate.
7. The spotting device for preparing the detection card according to claim 6, wherein the spotting device further comprises a blanking device, the blanking device comprises a first guide plate and a second guide plate, the first guide plate comprises a first guide portion matching with the shape of the portion of the driving belt sleeved on the driving transmission wheel or the driven transmission wheel, and a second guide portion connected to the lower end of the first arc portion and extending downward; the second guide plate is matched with the second guide part of the first guide plate in shape and is arranged at intervals, and a sliding channel is formed by a gap between the second guide plate and the second guide part; an end portion of an upper end of the second guide plate is located higher in a vertical direction than a portion of the transmission belt located below the transmission shaft.
8. The spotting device for preparing a detection card according to claim 7, wherein the second guide portion and the second guide plate are both arc-shaped plates, and an angle between a tangent of the arc-shaped surface of the arc-shaped plate and a horizontal direction gradually increases in a direction from top to bottom.
9. The spotting device for preparing a test card according to claim 7, wherein a plate collecting device is disposed below the conveyor belt, the plate collecting device comprises a plate collecting box, a plate collecting groove is disposed on the plate collecting box, the plate collecting groove is used for corresponding to the position of the slide passage to collect the spotted film plate sliding down in the slide passage, the plate collecting box is in guiding sliding fit with the moving frame or the base along the length direction of the conveyor belt, and a plate collecting driving mechanism is connected to the plate collecting box for driving the plate collecting box to slide along the length direction of the conveyor belt.
10. The spotting device for preparing the detection card according to any one of claims 1 to 9, characterized in that the top cover is provided with an air supply means for supplying hot air into the housing, the air supply means comprises an air supply groove provided in the top cover and a hot air ejection port provided on an inner surface of the top cover and communicating with the air supply groove, and the injection means comprises a transport groove provided in the top cover and an injection tube provided on an inner surface of the top cover.
CN202210174936.0A 2022-02-25 2022-02-25 Point membrane device is used in detection card preparation Active CN114534997B (en)

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CN112024278A (en) * 2020-08-13 2020-12-04 重庆数智源智能装备科技有限公司 LED lamp processing is with some adhesive deposite equipment that has adjustable route
CN213670195U (en) * 2020-09-23 2021-07-13 武汉瑞杰行智能科技有限公司 Three-axis glue dispensing mechanism for air conditioner base plate

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KR100465676B1 (en) * 2004-09-24 2005-01-13 디엔씨엔지니어링 주식회사 Apparatus for transporting a mold frame for back-light in mobile phone
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CN114264806B (en) * 2021-12-16 2024-03-29 苏州邦器生物技术有限公司 Membrane strip for immunoblotting and manufacturing method thereof

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